Einträge von Amaral, Margarida D. auf dem Publikationsserver

Jo, Sungwoo, Centeio, Raquel, Park, Jinhong, Ousingsawat, Jiraporn, Jeon, Dong‐kyu, Talbi, Khaoula, Schreiber, Rainer, Ryu, Kunhi, Kahlenberg, Kristin, Somoza, Veronika , Delpiano, Livia , Gray, Michael A., Amaral, Margarida D. , Railean, Violeta, Beekman, Jeffrey M., Rodenburg, Lisa W., Namkung, Wan und Kunzelmann, Karl (2022) The SLC26A9 inhibitor S9‐A13 provides no evidence for a role of SLC26A9 in airway chloride secretion but suggests a contribution to regulation of ASL pH and gastric proton secretion. The FASEB Journal 36 (11), e22534.

Rodenburg, Lisa W., Delpiano, Livia , Railean, Violeta, Centeio, Raquel, Pinto, Madalena C., Smits, Shannon M. A., van der Windt, Isabelle S., van Hugten, Casper F. J., van Beuningen, Sam F. B. , Rodenburg, Remco N. P., van der Ent, Cornelis K., Amaral, Margarida D. , Kunzelmann, Karl, Gray, Michael A., Beekman, Jeffrey M. und Amatngalim, Gimano D. (2022) Drug Repurposing for Cystic Fibrosis: Identification of Drugs That Induce CFTR-Independent Fluid Secretion in Nasal Organoids. International Journal of Molecular Sciences 23 (20), S. 12657. Volltext nicht vorhanden.

Pinto, Madalena C. , Botelho, Hugo M. , Silva, Iris A.L. , Railean, Violeta, Neumann, Beate , Pepperkok, Rainer, Schreiber, Rainer, Kunzelmann, Karl und Amaral, Margarida D. (2022) Systems Approaches to Unravel Molecular Function: High-content siRNA Screen Identifies TMEM16A Traffic Regulators as Potential Drug Targets for Cystic Fibrosis. Journal of Molecular Biology 434 (5), S. 167436. Volltext nicht vorhanden.

Pereira, Catarina , Mazein, Alexander, Farinha, Carlos M., Gray, Michael A., Kunzelmann, Karl, Ostaszewski, Marek, Balaur, Irina, Amaral, Margarida D. und Falcao, Andre O. (2021) CyFi-MAP: an interactive pathway-based resource for cystic fibrosis. Scientific Reports 11 (1). Volltext nicht vorhanden.

Silva, Iris A. L., Duarte, Aires, Marson, Fernando A. L. , Centeio, Raquel, Doušová, Tereza, Kunzelmann, Karl und Amaral, Margarida D. (2020) Assessment of Distinct Electrophysiological Parameters in Rectal Biopsies for the Choice of the Best Diagnosis/Prognosis Biomarkers for Cystic Fibrosis. Frontiers in Physiology 11. Volltext nicht vorhanden.

Sousa, Luis , Pankonien, Ines , Clarke, Luka A. , Silva, Iris , Kunzelmann, Karl und Amaral, Margarida D. (2020) KLF4 Acts as a wt-CFTR Suppressor through an AKT-Mediated Pathway. Cells 9 (7), S. 1607. Volltext nicht vorhanden.

Silva, Iris A.L., Doušová, Tereza, Ramalho, Sofia, Centeio, Raquel, Clarke, Luka A. , Railean, Violeta, Botelho, Hugo M., Holubová, Andrea, Valášková, Iveta, Yeh, Jiunn-Tyng, Hwang, Tzyh-Chang, Farinha, Carlos M., Kunzelmann, Karl und Amaral, Margarida D. (2020) Organoids as a personalized medicine tool for ultra-rare mutations in cystic fibrosis: The case of S955P and 1717-2A>G. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1866 (11), S. 165905. Volltext nicht vorhanden.

Lérias, Joana R., Pinto, Madalena C. , Botelho, Hugo M. , Awatade, Nikhil T., Quaresma, Margarida C., Silva, Iris A.L. , Wanitchakool, Podchanart, Schreiber, Rainer, Pepperkok, Rainer, Kunzelmann, Karl und Amaral, Margarida D. (2018) A novel microscopy-based assay identifies extended synaptotagmin-1 (ESYT1) as a positive regulator of anoctamin 1 traffic. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1865 (2), S. 421-431. Volltext nicht vorhanden.

Botelho, Hugo M. , Uliyakina, Inna , Awatade, Nikhil T. , Proença, Maria C., Tischer, Christian, Sirianant, Lalida, Kunzelmann, Karl, Pepperkok, Rainer und Amaral, Margarida D. (2015) Protein Traffic Disorders: an Effective High-Throughput Fluorescence Microscopy Pipeline for Drug Discovery. Scientific Reports 5 (1). Volltext nicht vorhanden.

Tosoni, Kendra, Stobbart, Michelle, Cassidy, Diane M., Venerando, Andrea, Pagano, Mario A. , Luz, Simão, Amaral, Margarida D. , Kunzelmann, Karl , Pinna, Lorenzo A. , Farinha, Carlos M. und Mehta, Anil (2013) CFTR mutations altering CFTR fragmentation. Biochemical Journal 449 (1), S. 295-305. Volltext nicht vorhanden.

Almaça, Joana , Faria, Diana , Sousa, Marisa, Uliyakina, Inna , Conrad, Christian, Sirianant, Lalida, Clarke, Luka A. , Martins, José Paulo , Santos, Miguel , Heriché, Jean-Karim , Huber, Wolfgang , Schreiber, Rainer, Pepperkok, Rainer , Kunzelmann, Karl und Amaral, Margarida D. (2013) High-Content siRNA Screen Reveals Global ENaC Regulators and Potential Cystic Fibrosis Therapy Targets. Cell 154 (6), S. 1390-1400. Volltext nicht vorhanden.

Hartl, Dominik , Sousa, Marisa, Servidoni, Maria F., Vinagre, Adriana M. , Ramalho, Anabela S., Bonadia, Luciana C., Felício, Verónica , Ribeiro, Maria A. , Uliyakina, Inna , Marson, Fernando A., Kmit, Arthur, Cardoso, Silvia R. , Ribeiro, José D., Bertuzzo, Carmen S. , Sousa, Lisete , Kunzelmann, Karl , Ribeiro, Antônio F. und Amaral, Margarida D. (2012) Measurements of CFTR-Mediated Cl− Secretion in Human Rectal Biopsies Constitute a Robust Biomarker for Cystic Fibrosis Diagnosis and Prognosis. PLoS ONE 7 (10), e47708. Volltext nicht vorhanden.

Faria, Diana , Lentze, Nicolas, Almaça, Joana , Luz, Simão, Alessio, Luisa, Tian, Yuemin, Martins, José Paulo , Cruz, Pedro , Schreiber, Rainer, Rezwan, Mandana, Farinha, Carlos Miguel , Auerbach, Daniel, Amaral, Margarida D. und Kunzelmann, Karl (2012) Regulation of ENaC biogenesis by the stress response protein SERP1. Pflügers Archiv - European Journal of Physiology 463 (6), S. 819-827. Volltext nicht vorhanden.

Luz, Simão, Kongsuphol, Patthara, Mendes, Ana Isabel, Romeiras, Francisco, Sousa, Marisa, Schreiber, Rainer, Matos, Paulo , Jordan, Peter , Mehta, Anil, Amaral, Margarida D. , Kunzelmann, Karl und Farinha, Carlos M. (2011) Contribution of Casein Kinase 2 and Spleen Tyrosine Kinase to CFTR Trafficking and Protein Kinase A-Induced Activity. Molecular and Cellular Biology 31 (22), S. 4392-4404. Volltext nicht vorhanden.

Faria, Diana , Dahimène, Shehrazade, Alessio, Luisa, Scott-Ward, Toby, Schreiber, Rainer, Kunzelmann, Karl und Amaral, Margarida D. (2011) Effect of Annexin A5 on CFTR: regulated traffic or scaffolding? Molecular Membrane Biology 28 (1), S. 14-29. Volltext nicht vorhanden.

Martins, Joana Raquel , Kongsuphol, Patthara, Sammels, Eva, Dahimène, Shehrazade, AlDehni, Fadi, Clarke, Luka Alexander , Schreiber, Rainer, de Smedt, Humbert, Amaral, Margarida D. und Kunzelmann, Karl (2011) F508del-CFTR increases intracellular Ca2+ signaling that causes enhanced calcium-dependent Cl− conductance in cystic fibrosis. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1812 (11), S. 1385-1392. Volltext nicht vorhanden.

Almaça, Joana , Kongsuphol, Patthara, Hieke, Bernhard, Ousingsawat, Jiraporn, Viollet, Benoit , Schreiber, Rainer, Amaral, Margarida D. und Kunzelmann, Karl (2010) Erratum to: AMPK controls epithelial Na+ channels through Nedd4-2 and causes an epithelial phenotype when mutated. Pflügers Archiv - European Journal of Physiology 460 (6), S. 1105-1106. Volltext nicht vorhanden.

Almaça, Joana , Kongsuphol, Patthara, Hieke, Bernhard, Ousingsawat, Jiraporn, Viollet, Benoit , Schreiber, Rainer, Amaral, Margarida D. und Kunzelmann, Karl (2009) AMPK controls epithelial Na+ channels through Nedd4-2 and causes an epithelial phenotype when mutated. Pflügers Archiv - European Journal of Physiology 458 (4), S. 713-721. Volltext nicht vorhanden.

Bachhuber, Tanja, Almaça, Joana , Aldehni, Fadi, Mehta, Anil, Amaral, Margarida D. , Schreiber, Rainer und Kunzelmann, Karl (2008) Regulation of the Epithelial Na+ Channel by the Protein Kinase CK2. Journal of Biological Chemistry 283 (19), S. 13225-13232. Volltext nicht vorhanden.

Amaral, Margarida D. und Kunzelmann, Karl (2007) Molecular targeting of CFTR as a therapeutic approach to cystic fibrosis. Trends in Pharmacological Sciences 28 (7), S. 334-341. Volltext nicht vorhanden.

Sousa, Marisa, Ousingsawat, Jiraporn, Seitz, Roswitha, Puntheeranurak, Supaporn, Regalado, Ana , Schmidt, André, Grego, Tiago , Jansakul, Chaweewan, Amaral, Margarida D. , Schreiber, Rainer und Kunzelmann, Karl (2006) An Extract from the Medicinal PlantPhyllanthus acidusand Its Isolated Compounds Induce Airway Chloride Secretion: A Potential Treatment for Cystic Fibrosis. Molecular Pharmacology 71 (1), S. 366-376. Volltext nicht vorhanden.

Mendes, Filipa , Wakefield, John, Bachhuber, Tanja, Barroso, Margarida , Bebok, Zsuzsa, Penque, Deborah , Kunzelmann, Karl und Amaral, Margarida D. (2005) Establishment and Characterization of a Novel Polarized MDCK Epithelial Cellular Model for CFTR Studies. Cellular Physiology and Biochemistry 16 (4-6), S. 281-290. Volltext nicht vorhanden.

Hirtz, Stephanie, Gonska, Tanja, Seydewitz, Hans H., Thomas, Jörg, Greiner, Peter, Kuehr, Joachim, Brandis, Matthias, Eichler, Irmgard, Rocha, Herculano, Lopes, Ana—Isabel, Barreto, Celeste, Ramalho, Anabela , Amaral, Margarida D. , Kunzelmann, Karl und Mall, Marcus (2004) CFTR Cl− channel function in native human colon correlates with the genotype and phenotype in cystic fibrosis. Gastroenterology 127 (4), S. 1085-1095. Volltext nicht vorhanden.