Startseite UR
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Schweihofer, Verena, Schulz, Daniela
, Blazquez, Raquel
, Brockhoff, Gero
, Ettl, Tobias
, Fiedler, Mathias
, Heimer, Sina, Schikora, Juliane, Bauer, Richard J.
und Wege, Anja Kathrin
(2025)
Multiplexed immune profiling and 3D co-culture assays to assess the individual checkpoint therapy response in head and neck squamous cell carcinoma.
Frontiers in Oncology 15.
Goerg, Alina, Piendl, Gerhard, Albert, Veruschka, Ortmann, Olaf
, Wege, Anja Kathrin
und Brockhoff, Gero
(2025)
Mdm2 targeting via PROteolysis TArgeting Chimeras (PROTAC) is efficient in p53 wildtype, p53-mutated, and abemaciclib-resistant estrogen receptor-positive cell lines and superior to mdm2 inhibition.
BMC Cancer 25 (1).
Schweihofer, Verena, Bruss, Christina, Seitz, Stephan, Glehr, Gunther
, Hetterich, Madeleine, Weber, Florian
, Hatzipanagiotou, Maria Eleni
, Fernández-Pacheco Álvarez, Miriam, Ortmann, Olaf
, Brockhoff, Gero
, Bauer, Richard J.
und Wege, Anja Kathrin
(2025)
Breast cancer scoring based on a multiplexed profiling of soluble and cell-associated (immune) markers facilitates the prediction of pembrolizumab therapy.
Cancer Cell International 25, S. 120.
Albert, Veruschka, Bruss, Christina, Tümen, Deniz, Piendl, Gerhard, Weber, Florian
, Dahl, Edgar, Seitz, Stephan, Ortmann, Olaf
, Wege, Anja K.
und Brockhoff, Gero
(2024)
HER4 Affects Sensitivity to Tamoxifen and Abemaciclib in Luminal Breast Cancer Cells and Restricts Tumor Growth in MCF-7-Based Humanized Tumor Mice.
International Journal of Molecular Sciences 25 (13), S. 7475.
Bruss, Christina, Albert, Veruschka, Seitz, Stephan, Blaimer, Stephanie
, Kellner, Kerstin, Pohl, Fabian, Ortmann, Olaf
, Brockhoff, Gero
und Wege, Anja K.
(2024)
Neoadjuvant radiotherapy in ER+, HER2+, and triple-negative -specific breast cancer based humanized tumor mice enhances anti-PD-L1 treatment efficacy.
Frontiers in Immunology 15.
Schulz, Daniela
, Feulner, Laura, Rubenich, Dominique S.
, Heimer, Sina, Rohrmüller, Sophia, Reinders, Yvonne, Falchetti, Marcelo, Wetzel, Martin, Braganhol, Elizandra
, Lummertz da Rocha, Edroaldo, Schäfer, Nicole, Stöckl, Sabine, Brockhoff, Gero
, Wege, Anja K.
, Fritsch, Jürgen
, Pohl, Fabian, Reichert, Torsten E., Ettl, Tobias
und Bauer, Richard J.
(2023)
Subcellular localization of PD‐L1 and cell‐cycle‐dependent expression of nuclear PD‐L1 variants: implications for head and neck cancer cell functions and therapeutic efficacy.
Molecular Oncology.
Bruss, Christina, Kellner, Kerstin, Albert, Veruschka, Hutchinson, James A.
, Seitz, Stephan, Ortmann, Olaf
, Brockhoff, Gero
und Wege, Anja K.
(2023)
Immune Checkpoint Profiling in Humanized Breast Cancer Mice Revealed Cell-Specific LAG-3/PD-1/TIM-3 Co-Expression and Elevated PD-1/TIM-3 Secretion.
Cancers 15 (9), S. 2615.
Bruss, Christina, Kellner, Kerstin, Ortmann, Olaf
, Seitz, Stephan, Brockhoff, Gero
, Hutchinson, James A.
und Wege, Anja Kathrin
(2022)
Advanced Immune Cell Profiling by Multiparameter Flow Cytometry in Humanized Patient-Derived Tumor Mice.
Cancers 14 (9), S. 2214.
Albert, Veruschka, Piendl, Gerhard, Yousseff, Dali, Lammert, Hedwig, Hummel, Michael, Ortmann, Olaf
, Jagla, Wolfgang, Gaumann, Andreas, Wege, Anja K.
und Brockhoff, Gero
(2022)
Protein kinase C targeting of luminal (T-47D), luminal/HER2-positive (BT474), and triple negative (HCC1806) breast cancer cells in-vitro with AEB071 (Sotrastaurin) is efficient but mediated by subtype specific molecular effects.
Archives of Gynecology and Obstetrics.
Schulz, Daniela, Wetzel, Martin, Eichberger, Jonas, Piendl, Gerhard, Brockhoff, Gero
, Wege, Anja K.
, Reichert, Torsten, Ettl, Tobias und Bauer, Richard J.
(2021)
Differential Expression of PD-L1 during Cell Cycle Progression of Head and Neck Squamous Cell Carcinoma.
International Journal of Molecular Sciences 22 (23), S. 1-18.
Wege, Anja Kathrin
, Dreyer, Tobias F., Teoman, Attila, Ortmann, Olaf
, Brockhoff, Gero und Bronger, Holger
(2021)
CX3CL1 Overexpression Prevents the Formation of Lung Metastases in Trastuzumab-Treated MDA-MB-453-Based Humanized Tumor Mice (HTM).
Cancers 2021 (13), S. 2459.
(Eingereicht)
, Krautbauer, Sabrina, Liebisch, Gerhard
, Wege, Anja Kathrin
, Melter, Michael
und Weiss, Thomas S.
(2019)
Bile acid-induced apoptosis and bile acid synthesis are reduced by over-expression of Augmenter of Liver Regeneration (ALR) in a STAT3-dependent mechanism.
Experimental Cell Research 374 (1), S. 189-197.
Volltext nicht vorhanden.
Riquelme, Paloma
, Haarer, Jan, Kammler, Anja, Walter, Lisa
, Tomiuk, Stefan, Ahrens, Norbert
, Wege, Anja K.
, Goecze, Ivan, Zecher, Daniel, Banas, Bernhard
, Spang, Rainer
, Fändrich, Fred, Lutz, Manfred B., Sawitzki, Birgit, Schlitt, Hans J.
, Ochando, Jordi
, Geissler, Edward K.
und Hutchinson, James A.
(2018)
TIGIT+ iTregs elicited by human regulatory macrophages control T cell immunity.
Nature Communications 9 (2858), S. 1-18.
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