Einträge von Jakob, Leonhard auf dem Publikationsserver

Willkomm, Sarah , Jakob, Leonhard, Kramm, Kevin, Graus, Veronika, Neumeier, Julia, Meister, Gunter und Grohmann, Dina (2022) Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2. Nature Communications 13, art.no.3825.

Wörle, Elisabeth, Jakob, Leonhard, Schmidbauer, Andreas, Zinner, Gabriel und Grohmann, Dina (2021) Decoupling the bridge helix of Cas12a results in a reduced trimming activity, increased mismatch sensitivity and impaired conformational transitions. Nucleic Acids Research 49 (9), S. 5278-5293. Volltext nicht vorhanden.

Aldag, Pierre, Welzel, Fabian, Jakob, Leonhard, Schmidbauer, Andreas, Rutkauskas, Marius, Fettes, Fergus, Grohmann, Dina und Seidel, Ralf (2021) Probing the stability of the SpCas9–DNA complex after cleavage. Nucleic Acids Research 49 (21), S. 12411-12421. Volltext nicht vorhanden.

Jakob, Leonhard, Gust, Alexander und Grohmann, Dina (2018) Evaluation and optimisation of unnatural amino acid incorporation and bioorthogonal bioconjugation for site-specific fluorescent labelling of proteins expressed in mammalian cells. Biochemistry and Biophysics Reports 2019 (17), S. 1-9.

Gust, Alexander, Jakob, Leonhard, Zeitler, Daniela M., Bruckmann, Astrid, Kramm, Kevin, Willkomm, Sarah, Tinnefeld, Philip, Meister, Gunter und Grohmann, Dina (2018) Site-Specific Labelling of Native Mammalian Proteins for Single-Molecule FRET Measurements. ChemBioChem 19 (8), S. 780-783. Volltext nicht vorhanden.

Jakob, Leonhard (2017) Structural and functional characterization of the RNA-binding proteins Loquacious and Brain tumor from Drosophila melanogaster. Dissertation, Universität Regensburg.

Heyam, Alex , Coupland, Claire E., Dégut, Clément, Haley, Ruth A., Baxter, Nicola J., Jakob, Leonhard, Aguiar, Pedro M. , Meister, Gunter, Williamson, Michael P., Lagos, Dimitris und Plevin, Michael J. (2017) Conserved asymmetry underpins homodimerization of Dicer-associated double-stranded RNA-binding proteins. Nucleic Acids Research 45 (21), S. 12577-12584. Volltext nicht vorhanden.

Jakob, Leonhard, Treiber, Thomas, Treiber, Nora, Gust, Alexander, Kramm, Kevin, Hansen, Kerrin, Stotz, Mathias, Wankerl, Ludwig, Herzog, Franz, Hannus, Stefan, Grohmann, Dina und Meister, Gunter (2016) Structural and functional insights into the fly microRNA biogenesis factor Loquacious. RNA 22 (3), S. 383-396. Volltext nicht vorhanden.

Hasler, Daniele, Lehmann, Gerhard, Murakawa, Yasuhiro, Klironomos, Filippos, Jakob, Leonhard, Grässer, Friedrich A., Rajewsky, Nikolaus, Landthaler, Markus und Meister, Gunter (2016) The Lupus Autoantigen La Prevents Mis-channeling of tRNA Fragments into the Human MicroRNA Pathway. Molecular Cell 63 (1), S. 110-124. Volltext nicht vorhanden.

Loedige, Inga, Jakob, Leonhard, Treiber, Thomas, Ray, Debashish, Stotz, Mathias, Treiber, Nora, Hennig, Janosch, Cook, Kate B. , Morris, Quaid, Hughes, Timothy R., Engelmann, Julia C. , Krahn, Michael P. und Meister, Gunter (2015) The Crystal Structure of the NHL Domain in Complex with RNA Reveals the Molecular Basis of Drosophila Brain-Tumor-Mediated Gene Regulation. Cell Rep (Cell Reports) 13 (6), S. 1206-1220.

Hauptmann, Judith, Schraivogel, Daniel , Bruckmann, Astrid, Manickavel, Sudhir, Jakob, Leonhard, Eichner, Norbert, Pfaff, Janina, Urban, Marc, Sprunck, Stefanie, Hafner, Markus , Tuschl, Thomas, Deutzmann, Rainer und Meister, Gunter (2015) Biochemical isolation of Argonaute protein complexes by Ago-APP. Proceedings of the National Academy of Sciences 112 (38), S. 11841-11845. Volltext nicht vorhanden.