Publikationen von 0000-0002-1326-4297
(ORCID: 0000-0002-1326-4297)

Kosch, Robin, Limm, Katharina, Staiger, Annette M., Kurz, Nadine S., Seifert, Nicole, Oláh, Bence, Solbrig, Stefan , Poeschel, Viola, Held, Gerhard, Ziepert, Marita, Schmitz, Norbert, Chteinberg, Emil, Siebert, Reiner, Spang, Rainer , Zacharias, Helena U., Ott, German, Oefner, Peter J. und Altenbuchinger, Michael (2025) Integration of high-throughput proteomic data and complementary omics layers with PriOmics. Genome Research, gr.279487.124. Volltext nicht vorhanden.

Simeth, Jakob , Engelmann, Simon, Mayr, Roman , Kaelble, Sebastian, Weber, Florian , Pichler, Renate, Dettmer, Katja , Oefner, Peter J. , Höring, Marcus , Symeou, Luisa, Freitag, Katharina, Wagner, Kilian, Burger, Maximilian, Herr, Wolfgang, Kreutz, Marina , Spang, Rainer , Liebisch, Gerhard und Siska, Peter J. (2025) Lipid metabolism of clear cell renal cell carcinoma predicts survival and affects intratumoral CD8 T cells. Translational Oncology 61, S. 102513.

Nozari, Zahra , Hüttl, Paul , Simeth, Jakob , Schön, Marian, Hutchinson, James A. , Spang, Rainer und Nikolski, Macha (2025) Harp: Data Harmonization for Computational Tissue Deconvolution across Diverse Transcriptomics Platforms. Bioinformatics.

Spang, Rainer und Ludwig, Bernd (2025) AI in Precision Medicine. KI - Künstliche Intelligenz 39, S. 3-6. Volltext nicht vorhanden.

Schill, Rudolf , Klever, Maren, Lösch, Andreas, Hu, Y. Linda , Vocht, Stefan, Rupp, Kevin, Grasedyck, Lars, Spang, Rainer und Beerenwinkel, Niko (2024) Correcting for Observation Bias in Cancer Progression Modeling. Journal of Computational Biology 31 (10), S. 927-945. Volltext nicht vorhanden.

Pfahler, Simon, Georg, Peter, Schill, Rudolf , Klever, Maren, Grasedyck, Lars, Spang, Rainer und Wettig, Tilo (2024) Taming numerical imprecision by adapting the KL divergence to negative probabilities. Statistics and Computing 34 (168).

Rupp, Kevin, Schill, Rudolf , Süskind, Jonas, Georg, Peter, Klever, Maren, Lösch, Andreas, Grasedyck, Lars, Wettig, Tilo und Spang, Rainer (2024) Differentiated uniformization: a new method for inferring Markov chains on combinatorial state spaces including stochastic epidemic models. Computational Statistics.

Schill, Rudolf , Klever, Maren, Rupp, Kevin, Hu, Y. Linda , Lösch, Andreas, Georg, Peter, Pfahler, Simon, Vocht, Stefan, Hansch, Stefan, Wettig, Tilo , Grasedyck, Lars und Spang, Rainer (2024) Reconstructing Disease Histories in Huge Discrete State Spaces. KI - Künstliche Intelligenz.

Schill, Rudolf, Klever, Maren, Lösch, Andreas, Hu, Y. Linda , Vocht, Stefan, Rupp, Kevin, Grasedyck, Lars, Spang, Rainer und Beerenwinkel, Niko (2023) Overcoming Observation Bias for Cancer Progression Modeling. bioRxiv. (Eingereicht)

Buck, Lena, Schmidt, Tobias, Feist, Maren, Schwarzfischer, Philipp, Kube, Dieter, Oefner, Peter J. , Zacharias, Helena U., Altenbuchinger, Michael , Dettmer, Katja , Gronwald, Wolfram und Spang, Rainer (2023) Anomaly detection in mixed high dimensional molecular data. Bioinformatics 39 (8), btad501.

Hu, Linda, Lösch, Andreas und Spang, Rainer (2023) Maschinelles lernen enthüllt den verborgenen Prozess der Tumorentstehung. Blick in die Wissenschaft : Forschungsmagazin der Universität Regensburg 31 (44/45), S. 52-53. Volltext nicht vorhanden.

Georg, Peter, Grasedyck, Lars, Klever, Maren, Schill, Rudolf , Spang, Rainer und Wettig, Tilo (2022) Low-rank tensor methods for Markov chains with applications to tumor progression models. Journal of Mathematical Biology 86 (7).

Schrod, Stefan, Schäfer, Andreas, Solbrig, Stefan, Lohmayer, Robert, Gronwald, Wolfram , Oefner, Peter J. , Beißbarth, Tim, Spang, Rainer , Zacharias, Helena und Altenbuchinger, Michael (2022) BITES: balanced individual treatment effect for survival data. Bioinformatics 38 (Suppl1), i60-i67.

Hassel, Jessica C., Schank, Timo E., Smetak, Heiko, Mühlbauer, Jasmin, Salzmann, Martin, Machiraju, Devayani, Menzer, Christian, Lang, Kristin, König, Laila, Haefner, Matthias F., Hülsmeyer, Ingrid, Kohler, Christian , Spang, Rainer , Enk, Alexander, Debus, Jürgen und Beckhove, Philipp (2022) Evaluation of radio-immunotherapy sequence on immunological responses and clinical outcomes in patients with melanoma brain metastases (ELEKTRA). Oncoimmunology 11 (1), S. 2066609.

Richter, Julia , John, Katharina, Staiger, Annette M., Rosenwald, Andreas, Kurz, Katrin, Michgehl, Ulf, Ott, German, Franzenburg, Sören, Kohler, Christian , Finger, Jasmin, Oschlies, Ilske, Paul, Ulrike, Siebert, Reiner, Spang, Rainer , Burkhardt, Birgit und Klapper, Wolfram (2021) Epstein-Barr virus status of sporadic Burkitt lymphoma is associated with patient age and mutational features. British journal of haematology 196 (3), S. 681-689.

Reinders, Jörg, Altenbuchinger, Michael, Limm, Katharina , Schwarzfischer, Philipp, Scheidt, Tamara, Strasser, Lisa, Richter, Julia, Szczepanowski, Monika, Huber, Christian G. , Klapper, Wolfram, Spang, Rainer und Oefner, Peter J. (2020) Platform independent protein-based cell-of-origin subtyping of diffuse large B-cell lymphoma in formalin-fixed paraffin-embedded tissue. Scientific Reports 10 (7876), S. 1-11.

Schoen, Marian, Simeth, Jakob , Heinrich, Paul, Goertler, F., Solbrig, Stefan, Wettig, Tilo, Oefner, Peter J., Altenbuchinger, Michael und Spang, Rainer (2020) DTD: An R Package for Digital Tissue Deconvolution. J. Comput. Biol.. Volltext nicht vorhanden.

Goertler, Franziska, Schoen, Marian, Simeth, Jakob , Solbrig, Stefan, Wettig, Tilo, Oefner, Peter J., Spang, Rainer und Altenbuchinger, Michael (2020) Loss-Function Learning for Digital Tissue Deconvolution. J. Comput. Biol.. Volltext nicht vorhanden.

Minderjahn, Julia, Schmidt, Andreas, Fuchs, Andreas , Schill, Rudolf, Raithel, Johanna, Babina, Magda , Schmidl, C. , Gebhard, Claudia, Schmidhofer, Sandra, Mendes, Karina , Ratermann, Anna, Glatz, Dagmar, Nützel, Margit, Edinger, Matthias, Hoffmann, Petra, Spang, Rainer , Längst, Gernot, Imhof, A. und Rehli, Michael (2020) Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1. Nat Commun 11, S. 402.

Schill, Rudolf, Solbrig, Stefan, Wettig, Tilo und Spang, Rainer (2020) Modelling cancer progression using Mutual Hazard Networks. Bioinformatics 36 (1), S. 241-249. Volltext nicht vorhanden.

Arlt, A., von Bonin, F., Rehberg, Thorsten, Perez-Rubio, Paula, Engelmann, Julia C. , Limm, Katharina , Reinke, S., Dullin, C., Sun, Xueni, Specht, R., Maulhardt, M., Linke, F. , Bunt, G., Klapper, W., Vockerodt, M., Wilting, J., Pukrop, T., Dettmer, Katja, Gronwald, Wolfram, Oefner, Peter J., Spang, Rainer und Kube, D. (2019) High CD206 levels in Hodgkin lymphoma-educated macrophages are linked to matrix-remodeling and lymphoma dissemination. Mol Oncol. Volltext nicht vorhanden.

Staiger, A. M., Altenbuchinger, Michael, Ziepert, M., Kohler, Christian, Horn, H., Huttner, Michael , Huttl, K. S., Glehr, Gunther , Klapper, W., Szczepanowski, M., Richter, J., Stein, H., Feller, A. C., Moller, P., Hansmann, M. L., Poeschel, V., Held, G., Loeffler, M., Schmitz, N., Trumper, L., Pukrop, T., Rosenwald, A., Ott, G., Spang, Rainer , Emed Demonstrator Project, und German High Grade Non-Hodgkin’s Lymphoma Study Group (DSHNHL), (2019) A novel lymphoma-associated macrophage interaction signature (LAMIS) provides robust risk prognostication in diffuse large B-cell lymphoma clinical trial cohorts of the DSHNHL. Leukemia 34, S. 543-552. Volltext nicht vorhanden.

Riquelme, Paloma , Haarer, Jan, Kammler, Anja, Walter, Lisa , Tomiuk, Stefan, Ahrens, Norbert , Wege, Anja K. , Goecze, Ivan, Zecher, Daniel, Banas, Bernhard , Spang, Rainer , Fändrich, Fred, Lutz, Manfred B., Sawitzki, Birgit, Schlitt, Hans J. , Ochando, Jordi , Geissler, Edward K. und Hutchinson, James A. (2018) TIGIT+ iTregs elicited by human regulatory macrophages control T cell immunity. Nature Communications 9 (2858), S. 1-18.