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(2025)
Synkopendiagnostik im Notfallzentrum – Stellenwert der ESC-Leitlinien.
Medizinische Klinik - Intensivmedizin und Notfallmedizin.
Zugang zum Volltext eingeschränkt.
Kunst, Claudia
(2024)
Liver Cirrhosis and epithelial damage - The Gut-Liver Axis in Spontaneous Bacterial Peritonitis and Its Modulation by p53.
In: EASL Congress 2024.
Weber, Florian
, Jung, Rudolf, Treeck, Oliver und Buechler, Christa
(2023)
Chemerin and Chemokine-like Receptor 1 Are Not Prognostic in Colorectal Carcinoma.
Anticancer Research 43 (2), S. 831-839.
, Cosma, Lidia-Sabina, Gülow, K., Müller, M. und Jung, Ernst Michael
(2022)
Multimodal ultrasound imaging with conventional B-mode, elastography, and parametric analysis of contrast-enhanced ultrasound (CEUS): A novel approach to assess small bowel manifestation in severe COVID-19 disease.
Clinical Hemorheology and Microcirculation pre-press.
(Im Druck)
Zugang zum Volltext eingeschränkt.
Hölzl, Fabian, Steindl, Carina, Haderer, Marika, Neubert, Philip, Mester-Pavel, Patricia, Kandulski, Arne, Kunst, Claudia, Gülow, Karsten und Müller-Schilling, Martina
(2022)
Bacterial-epithelial interplay in liver cirrhosis – regulation of intestinal epithelial barrier function, p53 proteins and cell death as a novel pathomechanism of bacterial translocation.
In: EASL - International Liver Congress 2022.
Hölzl, Fabian, Steindl, Carina, Haderer, Marika, Neubert, Philip, Mester-Pavel, Patricia, Kandulski, Arne, Kunst, Claudia, Gülow, Karsten und Müller-Schilling, Martina
(2022)
Bacterial-epithelial interplay in liver cirrhosis – regulation of intestinal epithelial barrier function, p53 proteins and cell death as a novel pathomechanism of bacterial translocation.
In: AASLD The liver meeting.
Kaser, Lisa, Ungermann, Emily, Kunst, Claudia, Gülow, Karsten und Müller-Schilling, Martina
(2022)
Coordinating expression of tumorsuppressive microRNAs in hepatocellular carcinoma – a new role for p63 and p73 and their interaction with therapeutic agents.
In: EASL - International Liver Congress 2022.
Tümen, Deniz
(2022)
Introduction of a novel exon-specific isofrom expression reporter system to analyze in real-time treatment-dependent induction of various p53 isoforms.
In: AASLD The liver meeting, November 4 - 8, 2022, Washington, DC.
(Eingereicht)
Walz, Franziska, Michalski, Marlen, Bauer, Magdalena, Müller-Schilling, Martina und Gülow, Karsten
(2022)
New therapeutic approach for the treatment of hepatocellular carcinoma: Inhibition of anti-apoptotic molecules Bcl-2 and Mcl-1.
In: AASLD The liver meeting.
Walz, Franziska, Michalski, Marlen, Bauer, Magdalena, Müller-Schilling, Martina und Gülow, Karsten
(2022)
New therapeutic approach for the treatment of hepatocellular carcinoma: Inhibition of anti-apoptotic molecules Bcl-2 and Mcl-1.
In: EASL - International Liver Congress 2022.
, Köstler, Josef, Siegmund, Heiko, Ugele, Ines, Paulus, Michael, Dietl, Alexander, Kolodova, Kristina, Steines, Louisa
, Freitag, Katharina, Peuker, Alice, Schönhammer, Gabriele, Raithel, Johanna, Graf, Bernhard, Geismann, Florian, Lubnow, Matthias, Mack, Matthias, Hau, Peter, Bohr, Christopher, Burkhardt, Ralph
, Gessner, André
, Salzberger, Bernd, Wagner, Ralf, Hanses, Frank, Hitzenbichler, Florian, Heudobler, Daniel, Lüke, Florian, Pukrop, Tobias, Herr, Wolfgang, Wolff, Daniel, Spang, Rainer, Poeck, Hendrik, Hoffmann, Petra, Jantsch, Jonathan, Brochhausen, Christoph, Lunz, Dirk, Rehli, Michael, Kreutz, Marina und Renner, Kathrin
(2021)
Metabolic imbalance of T cells in COVID-19 is hallmarked by basigin and mitigated by dexamethasone.
Journal of Clinical Investigation 131 (22), e148225.
Zugang zum Volltext eingeschränkt.
, Weigand, Kilian
, Peschel, Georg, Junger, Henrik, Kupke, Paul, Lang, Hauke, Marquardt, Jens U., Zimmermann, Tim, Geissler, Edward K.
, Schlitt, Hans J.
und Werner, Jens M.
(2021)
Ribavirin Improves NK Cell IFNγ Response During Sofosbuvir-based DAA Therapy in HCV-infected Liver Transplant Recipients.
Transplantation 105 (10), S. 2226-2238.
Zugang zum Volltext eingeschränkt.
, Pohl, R., Rein-Fischboeck, L., Weiss, Thomas S.
und Buechler, Christa
(2017)
Hepatic tumour burden is reduced by endogenous overexpression of chemerin-157.
Journal of Hepatology 66 (1suppl), S226.
Volltext nicht vorhanden.
und Buechler, Christa
(2015)
Hepatic scavenger receptor BI is associated with type 2 diabetes but unrelated to human and murine non-alcoholic fatty liver disease.
Biochemical and Biophysical Research Communications 467 (2), S. 377-382.
Volltext nicht vorhanden.
, Weiss, Thomas S.
, Ruemmele, Petra, Kollmar, Otto, Hoffmann, Patrick, Grässer, Friedrich, Allgayer, Heike, Fabian, Jasmin, Weng, Hong Lei, Teufel, Andreas, Maass, Thorsten, Meyer, Christoph, Lehmann, Ulrich, Zhu, Cheng, Mertens, Peter R., Gao, Chun Fang, Dooley, Steven und Meindl-Beinker, Nadja M.
(2015)
Smad7 regulates compensatory hepatocyte proliferation in damaged mouse liver and positively relates to better clinical outcome in human hepatocellular carcinoma.
Clinical Science 128 (11), S. 761-774.
Volltext nicht vorhanden.
und Buechler, Christa
(2015)
Reduced serum chemerin in patients with more severe liver cirrhosis.
Experimental and Molecular Pathology 98 (2), S. 208-213.
Volltext nicht vorhanden.
und Buechler, Christa
(2013)
Manganese superoxide dismutase is reduced in the liver of male but not female humans and rodents with non-alcoholic fatty liver disease.
Experimental and Molecular Pathology 95 (3), S. 330-335.
Volltext nicht vorhanden.
, Bosserhoff, A. und Hellerbrand, C.
(2012)
316 FAT1 EXPRESSION IS INCREASED IN HEPATOCELLULAR CARCINOMA AND PROMOTES TUMORIGENESIS.
Journal of Hepatology 56 (2), S129.
Volltext nicht vorhanden.
, Wiest, Reiner, Schacherer, Doris, Hellerbrand, Claus, Farkas, Stefan, Scherer, Marcus N., Ritter, Mirko, Schmitz, Gerd
, Schäffler, Andreas und Buechler, Christa
(2012)
Corrigendum to “Soluble CD163 is not increased in visceral fat and steatotic liver and is even suppressed by free fatty acids in-vitro” [Exp. Mol. Pathol. 91-3 (2011) 733–739].
Experimental and Molecular Pathology 93 (2), S. 283.
Volltext nicht vorhanden.
, Walter, Roland, Hellerbrand, Claus, Schäffler, Andreas, Higuchi, Akiko, Walsh, Kenneth und Buechler, Christa
(2012)
Corrigendum to “Adiponectin upregulates hepatocyte CMKLR1 which is reduced in human fatty liver” [Molecular and Cellular Endocrinology 349 (2012) 248–254].
Molecular and Cellular Endocrinology 355 (1), S. 190.
Volltext nicht vorhanden.
, Walter, Roland, Hellerbrand, Claus, Schäffler, Andreas, Higuchi, Akiko, Walsh, Kenneth und Buechler, Christa
(2011)
Adiponectin upregulates hepatocyte CMKLR1 which is reduced in human fatty liver.
Molecular and Cellular Endocrinology 349 (2), S. 248-254.
Volltext nicht vorhanden.
, Amann, Thomas, Hellerbrand, Claus, Schäffler, Andreas, Schölmerich, Jürgen und Buechler, Christa
(2011)
Adiponectin reduces connective tissue growth factor in human hepatocytes which is already induced in non-fibrotic non-alcoholic steatohepatitis.
Experimental and Molecular Pathology 91 (3), S. 740-744.
Volltext nicht vorhanden.
, Wiest, Reiner, Schacherer, Doris, Hellerbrand, Claus, Farkas, Stefan, Scherer, Marcus N., Ritter, Mirko, Schmitz, Gerd
, Schäffler, Andreas und Buechler, Christa
(2011)
Soluble CD163 is not increased in visceral fat and steatotic liver and is even suppressed by free fatty acids in vitro.
Experimental and Molecular Pathology 91 (3), S. 733-739.
Volltext nicht vorhanden.
, Hellerbrand, Claus, Neumeier, Markus, Schäffler, Andreas und Buechler, Christa
(2011)
Systemic and hepatic vein galectin-3 are increased in patients with alcoholic liver cirrhosis and negatively correlate with liver function.
Cytokine 55 (3), S. 435-440.
Volltext nicht vorhanden.
, Hellerbrand, Claus
, Schoelmerich, Juergen und Buechler, Christa
(2011)
Antifibrotic effects of adiponectin include induction of BMP-activated and membrane bound inhibitor (Bambi) in liver cells which antagonizes TGF-beta activity.
Zeitschrift für Gastroenterologie 49 (2), P1_56.
Volltext nicht vorhanden.
(2011)
Does Hepatic Steatosis Affect Drug Metabolizing Enzymes in the Liver?
Current Drug Metabolism 12 (1), S. 24-34.
Volltext nicht vorhanden.
, Huber, Hanna, Schäffler, Andreas, Aslanidis, Charalampos, Schölmerich, Jürgen und Buechler, Christa
(2010)
Lipid accumulation impairs adiponectin-mediated induction of activin A by increasing TGFbeta in primary human hepatocytes.
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1811 (10), S. 626-633.
Volltext nicht vorhanden.
, Schneider, Ursula, Kopitz, Jürgen, Weiss, Thomas S.
, Hellerbrand, Claus, Weiskirchen, Ralf
, Knüchel, Ruth und Gassler, Nikolaus
(2010)
Lipid-induced up-regulation of human acyl-CoA synthetase 5 promotes hepatocellular apoptosis.
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1801 (9), S. 1025-1035.
Volltext nicht vorhanden.
, Weiss, Thomas S.
, Schlitt, Hans J., Geissler, Edward K., Hellerbrand, Claus und Stoeltzing, Oliver
(2009)
Effect of heat-shock protein-90 (HSP90) inhibition on human hepatocytes and on liver regeneration in experimental models.
Surgery 147 (5), S. 704-712.
Volltext nicht vorhanden.
, Haudek, Verena J., Zwickl, Hannes, Gundacker, Nina C., Grusch, Michael
, Weiss, Thomas S.
, Seir, Katja, Rodgarkia-Dara, Chantal, Hellerbrand, Claus und Gerner, Christopher
(2009)
Cell Characterization by Proteome Profiling Applied to Primary Hepatocytes and Hepatocyte Cell Lines Hep-G2 and Hep-3B.
Journal of Proteome Research 9 (1), S. 6-21.
Volltext nicht vorhanden.
, Wodarz, Norbert, Kiefer, Paul und Hellerbrand, Claus
(2009)
Elevated adiponectin serum levels in patients with chronic alcohol abuse rapidly decline during alcohol withdrawal.
Journal of Gastroenterology and Hepatology 24 (4), S. 558-563.
Volltext nicht vorhanden.
, Weiss, Thomas S.
, Schäffler, Andreas, Aslanidis, Charalampos, Schmitz, Gerd, Schölmerich, Jürgen und Buechler, Christa
(2008)
Metformin reduces cellular lysophosphatidylcholine and thereby may lower apolipoprotein B secretion in primary human hepatocytes.
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1781 (6-7), S. 321-325.
Volltext nicht vorhanden.
, Dobner, T., Groitl, P., Thasler, W. E., Hellerbrand, Claus
, Bosserhoff, A. K.
, Schlitt, H. J. und Weiss, Thomas S.
(2008)
510 THE FORKHEAD BOX A2 TRANSCRIPTION FACTOR REGULATES THE HEPATOTROPHIC PROTEIN ALR (AUGMENTER OF LIVER REGENERATION).
Journal of Hepatology 48 (2), S193.
Volltext nicht vorhanden.
, Schoelmerich, J. und Hellerbrand, Claus
(2008)
983 LIPID ACCUMULATION INDUCES PRODUCTION OF PRO-INFLAMMATORY INTERLEUKIN-8 IN HUMAN HEPATOCYTES VIA ACTIVATION OF JNK - A POTENTIAL STEP IN THE PROGRESSION TO NASH.
Journal of Hepatology 48 (2), S367.
Volltext nicht vorhanden.
, Schoelmerich, J. und Hellerbrand, Claus
(2008)
983 LIPID ACCUMULATION INDUCES PRODUCTION OF PRO-INFLAMMATORY INTERLEUKIN-8 IN HUMAN HEPATOCYTES VIA ACTIVATION OF JNK - A POTENTIAL STEP IN THE PROGRESSION TO NASH.
Journal of Hepatology 48 (2), S367.
Volltext nicht vorhanden.
, Bollheimer, C., Buettner, R., Schoelmerich, J. und Hellerbrand, Claus
(2007)
[772] LIPID ACCUMULATION IN HEPATOCYTES INDUCES ACTIVATION AND PRO-FIBROTIC GENE EXPRESSION IN HEPATIC STELLATE CELLS - A NEW IN VITRO MODEL TO STUDY FIBROGENESIS IN NASH.
Journal of Hepatology 46 (1), S290.
Volltext nicht vorhanden.
, Bollheimer, C., Buettner, R., Schoelmerich, J. und Hellerbrand, Claus
(2007)
[772] LIPID ACCUMULATION IN HEPATOCYTES INDUCES ACTIVATION AND PRO-FIBROTIC GENE EXPRESSION IN HEPATIC STELLATE CELLS - A NEW IN VITRO MODEL TO STUDY FIBROGENESIS IN NASH.
Journal of Hepatology 46 (1), S290.
Volltext nicht vorhanden.
, Netter, Susanne, Neumaier, Daniel
, Gaebele, Erwin, Wiest, Reiner, Schoelmerich, Juergen und Froh, Matthias
(2007)
Characterization of rat and human Kupffer cells after cryopreservation.
Cryobiology 54 (2), S. 164-172.
Volltext nicht vorhanden.
, Schaeffler, Andreas, Schlitt, Hans J., Aslanidis, Charalampos, Piso, Pompiliu, Langmann, Thomas, Schmitz, Gerd, Schölmerich, Jürgen und Buechler, Christa
(2006)
High molecular weight adiponectin reduces apolipoprotein B and E release in human hepatocytes.
Biochemical and Biophysical Research Communications 352 (2), S. 543-548.
Volltext nicht vorhanden.
, Weiss, Thomas S.
, Netter, Susanne, Gäbele, Erwin, Mühlbauer, Marcus, Wiest, Reiner
, Schölmerich, Jürgen und Froh, Matthias
(2006)
Cryopreservation of human kupffer cells.
In: 57th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, OCT 27-31, 2006, Boston, MA.
Volltext nicht vorhanden.
, Schmidl, Christian, Büttner, Roland, Bollheimer, Cornelius, Aslanidis, Charalampos, Schölmerich, Jürgen und Buechler, Christa
(2006)
Aldehyde oxidase 1 is highly abundant in hepatic steatosis and is downregulated by adiponectin and fenofibric acid in hepatocytes in vitro.
Biochemical and Biophysical Research Communications 350 (3), S. 731-735.
Volltext nicht vorhanden.
, Froh, Matthias, Blank, Christian, Schölmerich, Jürgen und Hellerbrand, Claus
(2006)
PD-L1 is induced in hepatocytes by viral infection and by interferon-α and -γ and mediates T cell apoptosis.
Journal of Hepatology 45 (4), S. 520-528.
Volltext nicht vorhanden.
, Gäbele, E., Bollheimer, C., Weigert, J., Weiss, Thomas S.
, Lichtenauer, M., Schölmerich, J. und Büchler, Christa
(2006)
Adiponectin and adiponectin receptors AdipoR1 and AdipoR2 in rodent models of fatty liver and liver cirrhosis.
Medizinische Klinik 101 (4), A15.
Volltext nicht vorhanden.
, Froh, Matthias, Schütz, C., Blank, C., Schölmerich, Jürgen und Hellerbrand, C.
(2006)
PD-L1 expression in human hepatocytes induces T-cell apoptosis.
Medizinische Klinik 101 (4), A23.
Volltext nicht vorhanden.
, Letschert, K., Tausch, U., Jilg, Wolfgang, Hellerbrand, Claus
und Jauch, K. W.
(2006)
The human liver in vitro model: Potential of primary human hepatocytes for experimental and clinical research.
Langenbeck's Archives of Surgery 386 (6), S. 475-476.
Volltext nicht vorhanden.
, Kirchner, Stefan, Laberer, Sabine, Schölmerich, Jürgen und Buechler, Christa
(2005)
Regulation of adiponectin receptor 1 in human hepatocytes by agonists of nuclear receptors.
Biochemical and Biophysical Research Communications 334 (3), S. 924-929.
Volltext nicht vorhanden.
(2005)
Expression of augmenter of liver regeneration (ALR) in human liver cirrhosis and carcinoma.
Histopathology 47 (1), S. 57-66.
Volltext nicht vorhanden.
, Gäbele, Erwin, Wünsch, Peter, Schölmerich, Jürgen und Hellerbrand, Claus
(2005)
Lack of association between the functional CX3CR1 polymorphism V249I and hepatocellular carcinoma.
Oncology Reports 13 (5), S. 957-963.
Volltext nicht vorhanden.
, Thasler, Wolfgang E., Gelbmann, Cornelia M., Schnabl, Bernd, Schölmerich, Jürgen und Hellerbrand, Claus
(2004)
LPS-mediated NFκB activation varies between activated human hepatic stellate cells from different donors.
Biochemical and Biophysical Research Communications 325 (1), S. 191-197.
Volltext nicht vorhanden.
, Thasler, Wolfgang E., Gelbmann, Cornelia M., Schnabl, Bernd, Schölmerich, Jürgen und Hellerbrand, Claus
(2004)
LPS-mediated NFκB activation varies between activated human hepatic stellate cells from different donors.
Biochemical and Biophysical Research Communications 325 (1), S. 191-197.
Volltext nicht vorhanden.
, Herfarth, H., Obermeier, F., Ouart, J., Vogl, D., Schölmerich, Jürgen, Jauch, K. W. und Rogler, G.
(2004)
Intracellular Polyamine Levels of Intestinal Epithelial Cells in Inflammatory Bowel Disease.
Inflammatory Bowel Diseases 10 (5), S. 529-535.
Volltext nicht vorhanden.
, Gregor, M. und Bitzer, M.
(2003)
Adenoviral gene transfer of tumor necrosis factor-related apoptosis-inducing ligand overcomes an impaired response of hepatoma cells but causes severe apoptosis in primary human hepatocytes.
Cancer Research 63 (10), S. 2369-2372.
Volltext nicht vorhanden.
, Schölmerich, Jürgen und Hellerbrand, Claus
(2002)
An in vitro model with kryoconserved human activated hepatic stellate cells: Reflecting heterogeneity of profibrotic and proinflammatory gene expression.
In: 53rd Annual Meeting of the Association-for-the-Study-of-Liver-Diseases (AASLD), NOV 01-05, 2002, BOSTON, MASSACHUSETTS.
Volltext nicht vorhanden.
, Bader, R., Jauch, K. W. und Singer, T.
(2001)
Use of primary rat and human hepatocytes in early peclinical drug safety evaluation.
Naunyn - Schmiedebergs Archives of Pharmacology 363 (4), R163.
Volltext nicht vorhanden.
, Abels, C., Hellerbrand, Claus
, Bolder, U., Wagner, J., Szeimies, R. M. und Jauch, Karl-Walter
(1999)
Oxidative cell damage induced by repeated application of 5-aminolevulinic acid in human hepatocyte cultures.
Hepatology 30 (4), 400A.
Volltext nicht vorhanden.
, Weinberger, K. M., Bolder, U. und Jauch, Karl-Walter
(1999)
Vaccinia mediated gene transfer into human hepatocytes - Efficiency and function under transplant conditions in vitro.
Langenbecks Archives of Surgery (1), S. 247-251.
Volltext nicht vorhanden.
, Bernhardt, G., Buschauer, Armin
, Spruss, Thilo, Dolgner, Doris, Jauch, K. W. und Zirngibl, H.
(1997)
An in vitro / in vivo model for studying the role of polyamines in human pancreatic carcinoma.
Gastroenterology 112 (4), A1485.
Volltext nicht vorhanden.
, Heinmoeller, E., Buschauer, Armin
, Bernhardt, Günther
, Gruber, R., Rueschoff, J. und Zirngibl, H.
(1996)
A new HPLC-method for the determination of polyamines (PA) in the subpicomolar range: PA and ornithine-decarboxylase (ODC) in human pancreatic carcinoma cell lines.
European Journal of Cell Biology 69 (42), S. 157.
Volltext nicht vorhanden.
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