Anzahl der Einträge: 24.
2024
Hammon, Kathrin,
Renner, Kathrin,
Althammer, Michael,
Voll, Florian,
Babl, Nathalie,
Decking, Sonja-Maria,
Siska, Peter J. ,
Matos, Carina,
Conejo, Zugey Elizabeth Cárdenas,
Mendes, Karina ,
Einwag, Friederike,
Siegmund, Heiko,
Iberl, Sabine,
Berger, Raffaela S. ,
Dettmer, Katja,
Schoenmehl, Rebecca,
Brochhausen, Christoph ,
Herr, Wolfgang,
Oefner, Peter J. ,
Rehli, Michael ,
Thomas, Simone und
Kreutz, Marina
(2024)
D-2-hydroxyglutarate supports a tolerogenic phenotype with lowered major histocompatibility class II expression in non-malignant dendritic cells and acute myeloid leukemia cells.
Haematologica.
2023
2022
Harrer, Dennis Christoph,
Heidenreich, Martin,
Fante, Matthias Alexander,
Müller, Viktoria,
Hähnel, Viola,
Offner, Robert,
Burkhardt, Ralph ,
Herr, Wolfgang,
Edinger, Matthias,
Wolff, Daniel,
Thomas, Simone und
Brosig, Andreas
(2022)
Apheresis for chimeric antigen receptor T‐cell production in adult lymphoma patients.
Transfusion 62 (8), S. 1602-1611.
Zugang zum Volltext eingeschränkt.
Decking, Sonja-Maria,
Bruss, Christina,
Babl, Nathalie,
Bittner, Sebastian,
Klobuch, Sebastian,
Thomas, Simone ,
Feuerer, Markus,
Hoffmann, Petra,
Dettmer, Katja ,
Oefner, Peter J. ,
Renner, Kathrin und
Kreutz, Marina
(2022)
LDHB Overexpression Can Partially Overcome T Cell Inhibition by Lactic Acid.
International journal of molecular sciences 23 (11), S. 5970.
Krauter, Steffi,
Büscher, Nicole,
Bräuchle, Eric,
Ortega Iannazzo, Samira,
Penner, Inessa,
Krämer, Nadine,
Gogesch, Patricia,
Thomas, Simone,
Kreutz, Marina,
Dejung, Mario,
Freiwald, Anja,
Butter, Falk,
Waibler, Zoe und
Plachter, Bodo
(2022)
An Attenuated Strain of Human Cytomegalovirus for the Establishment of a Subviral Particle Vaccine.
Vaccines 10 (8), S. 1326.
Volltext nicht vorhanden.
Bethge, Wolfgang Andreas ,
Martus, Peter,
Schmitt, Michael,
Holtick, Udo,
Subklewe, Marion,
von Tresckow, Bastian ,
Ayuk, Francis,
Wagner-Drouet, Eva Maria,
Wulf, Gerald G,
Marks, Reinhard,
Penack, Olaf,
Schnetzke, Ulf,
Koenecke, Christian ,
von Bonin, Malte ,
Stelljes, Matthias,
Glass, Bertram,
Baldus, Claudia D,
Vucinic, Vladan ,
Mougiakakos, Dimitrios,
Topp, Max S,
Fante, Matthias Alexander,
Schroers, Roland,
Bayir, Lale May,
Borchmann, Peter,
Buecklein, Veit,
Hanoun, Christine,
Thomas, Simone,
Beelen, Dietrich W.,
Lengerke, Claudia,
Kroeger, Nicolaus,
Dreger, Peter und
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(2022)
GLA/DRST real-world outcome analysis of CAR-T cell therapies for large B-cell lymphoma in Germany.
Blood.
Volltext nicht vorhanden.
2021
Oefner, Peter J. ,
Dettmer, Katja ,
Berger, Raffaela Sarah,
Wachsmuth, Christian J.,
Waldhier, Magdalena C.,
Renner-Sattler, Kathrin,
Thomas, Simone,
Chaturvedi, Anuhar ,
Niller, Hans Helmut,
Bumes, Elisabeth,
Hau, Peter ,
Proescholdt, Martin A.,
Gronwald, Wolfram ,
Heuser, Michael und
Kreutz, Marina
(2021)
Lactonization of the Oncometabolite D-2-Hydroxyglutarate Produces a Novel Endogenous Metabolite.
Cancers 2021 (13), S. 1756.
Jetani, Hardikkumar,
Navarro-Bailón, Almudena,
Maucher, Marius,
Frenz, Silke,
Verbruggen, Christina,
Yeguas, Ana,
Vidriales, María Belén,
González, Marcos,
Rial Saborido, Judit,
Kraus, Sabrina,
Mestermann, Katrin,
Thomas, Simone,
Bonig, Halvard,
Luu, Maik,
Monjezi, Razieh,
Mougiakakos, Dimitrios,
Sauer, Markus,
Einsele, Hermann und
Hudecek, Michael
(2021)
Siglec-6 is a novel target for CAR T-cell therapy in acute myeloid leukemia.
Blood 138 (19), S. 1830-1842.
Volltext nicht vorhanden.
2020
Klobuch, Sebastian ,
Hammon, Kathrin,
Vatter-Leising, Sarah,
Neidlinger, Elisabeth,
Zwerger, Michael,
Wandel, Annika,
Neuber, Laura Maria,
Heilmeier, Bernhard,
Fichtner, Regina,
Mirbeth, Carina,
Herr, Wolfgang und
Thomas, Simone
(2020)
HLA-DPB1 Reactive T Cell Receptors for Adoptive Immunotherapy in Allogeneic Stem Cell Transplantation.
Cells 9 (1264), S. 1-15.
2019
2018
Heudobler, Daniel,
Rechenmacher, Michael,
Lüke, Florian,
Vogelhuber, Martin,
Klobuch, Sebastian,
Thomas, Simone,
Pukrop, Tobias,
Hackl, Christina,
Herr, Wolfgang,
Ghibelli, Lina,
Gerner, Christopher und
Reichle, Albrecht
(2018)
Clinical Efficacy of a Novel Therapeutic Principle, Anakoinosis.
Frontiers in Pharmacology 9 (1357), S. 1-26.
Klobuch, Sebastian,
Steinberg, Tim,
Bruni, Emanuele,
Mirbeth, Carina,
Heilmeier, Bernhard,
Ghibelli, Lina,
Herr, Wolfgang,
Reichle, Albrecht und
Thomas, Simone
(2018)
Biomodulatory Treatment With Azacitidine, All-trans Retinoic Acid and Pioglitazone Induces Differentiation of Primary AML Blasts Into Neutrophil Like Cells Capable of ROS Production and Phagocytosis.
Frontiers in Pharmacology 9 (1380), S. 1-11.
Heudobler, Daniel,
Klobuch, Sebastian,
Thomas, Simone ,
Hahn, Joachim,
Herr, Wolfgang und
Reichle, Albrecht
(2018)
Cutaneous leukemic infiltrates successfully treated with biomodulatory therapy in a rare case of therapy-related high risk MDS/AML.
Frontiers in Pharmacology 9 (1279), S. 1-5.
Renner, Kathrin,
Seilbeck, Anton,
Kauer, Nathalie,
Ugele, Ines,
Siska, Peter J.,
Brummer, Christina,
Bruss, Christina,
Decking, Sonja-Maria,
Fante, Matthias,
Schmidt, Astrid,
Hammon, Kathrin,
Singer, Katrin,
Klobuch, Sebastian,
Thomas, Simone ,
Gottfried, Eva,
Peter, Katrin und
Kreutz, Marina
(2018)
Combined Metabolic Targeting With Metformin and the NSAIDs Diflunisal and Diclofenac Induces Apoptosis in Acute Myeloid Leukemia Cells.
Frontiers in Pharmacology 9 (1258), S. 1-13.
Böttcher, Martin,
Renner, Kathrin,
Berger, Raffaela ,
Mentz, Kristin,
Thomas, Simone ,
Cardenas-Conejo, Zugey Elizabeth,
Dettmer, Katja,
Oefner, Peter J.,
Mackensen, Andreas,
Kreutz, Marina und
Mougiakakos, Dimitrios
(2018)
D-2-hydroxyglutarate interferes with HIF-1α stability skewing T-cell metabolism towards oxidative phosphorylation and impairing Th17 polarization.
OncoImmunology 7 (7), e1445454.
Jetani, Hardikkumar,
Garcia-Cadenas, Irene,
Nerreter, Thomas ,
Thomas, Simone ,
Rydzek, Julian,
Meijide, Javier Briones ,
Bonig, Halvard,
Herr, Wolfgang,
Sierra, Jordi,
Einsele, Hermann und
Hudecek, Michael
(2018)
CAR T-cells targeting FLT3 have potent activity against FLT3−ITD+ AML and act synergistically with the FLT3-inhibitor crenolanib.
Leukemia 32 (5), S. 1168-1179.
Volltext nicht vorhanden.
Kiener, Richard,
Fleischmann, Markus,
Wiegand, Marian Alexander,
Lemmermann, Niels A. W. ,
Schwegler, Christiane,
Kaufmann, Christine,
Renzaho, Angelique,
Thomas, Simone ,
Felder, Eva,
Niller, Hans Helmut,
Asbach, Benedikt,
Wagner, Ralf und
Jung, Jae U.
(2018)
Efficient Delivery of Human Cytomegalovirus T Cell Antigens by Attenuated Sendai Virus Vectors.
Journal of Virology 92 (15).
Volltext nicht vorhanden.
Vatter, Sarah,
Schmid, Maximilian,
Gebhard, Claudia,
Mirbeth, Carina,
Klobuch, Sebastian,
Rehli, Michael,
Herr, Wolfgang und
Thomas, Simone
(2018)
In-vitro blockade of the CD4 receptor co-signal in antigen-specific T-cell stimulation cultures induces the outgrowth of potent CD4 independent T-cell effectors.
Journal of Immunological Methods 454, S. 80-85.
Volltext nicht vorhanden.
Mathew, Nimitha R.,
Baumgartner, Francis,
Braun, Lukas,
O'Sullivan, David,
Thomas, Simone ,
Waterhouse, Miguel,
Müller, Tony A.,
Hanke, Kathrin,
Taromi, Sanaz,
Apostolova, Petya,
Illert, Anna L.,
Melchinger, Wolfgang,
Duquesne, Sandra,
Schmitt-Graeff, Annette,
Osswald, Lena,
Yan, Kai-Li,
Weber, Arnim,
Tugues, Sonia,
Spath, Sabine ,
Pfeifer, Dietmar,
Follo, Marie,
Claus, Rainer,
Lübbert, Michael,
Rummelt, Christoph,
Bertz, Hartmut,
Wäsch, Ralph,
Haag, Johanna,
Schmidts, Andrea ,
Schultheiss, Michael,
Bettinger, Dominik,
Thimme, Robert,
Ullrich, Evelyn ,
Tanriver, Yakup ,
Vuong, Giang Lam,
Arnold, Renate,
Hemmati, Philipp,
Wolf, Dominik,
Ditschkowski, Markus,
Jilg, Cordula,
Wilhelm, Konrad,
Leiber, Christian,
Gerull, Sabine,
Halter, Jörg,
Lengerke, Claudia ,
Pabst, Thomas,
Schroeder, Thomas,
Kobbe, Guido,
Rösler, Wolf,
Doostkam, Soroush,
Meckel, Stephan ,
Stabla, Kathleen,
Metzelder, Stephan K.,
Halbach, Sebastian ,
Brummer, Tilman ,
Hu, Zehan,
Dengjel, Joern ,
Hackanson, Björn,
Schmid, Christoph,
Holtick, Udo,
Scheid, Christof,
Spyridonidis, Alexandros,
Stölzel, Friedrich,
Ordemann, Rainer,
Müller, Lutz P.,
Sicre-de-Fontbrune, Flore,
Ihorst, Gabriele,
Kuball, Jürgen,
Ehlert, Jan E.,
Feger, Daniel,
Wagner, Eva-Maria,
Cahn, Jean-Yves,
Schnell, Jacqueline,
Kuchenbauer, Florian,
Bunjes, Donald,
Chakraverty, Ronjon ,
Richardson, Simon ,
Gill, Saar,
Kröger, Nicolaus,
Ayuk, Francis,
Vago, Luca ,
Ciceri, Fabio,
Müller, Antonia M.,
Kondo, Takeshi ,
Teshima, Takanori,
Klaeger, Susan,
Kuster, Bernhard,
Kim, Dennis (Dong Hwan),
Weisdorf, Daniel,
van der Velden, Walter,
Dörfel, Daniela,
Bethge, Wolfgang,
Hilgendorf, Inken,
Hochhaus, Andreas,
Andrieux, Geoffroy,
Börries, Melanie,
Busch, Hauke ,
Magenau, John,
Reddy, Pavan,
Labopin, Myriam,
Antin, Joseph H.,
Henden, Andrea S. ,
Hill, Geoffrey R.,
Kennedy, Glen A.,
Bar, Merav,
Sarma, Anita,
McLornan, Donal,
Mufti, Ghulam,
Oran, Betul,
Rezvani, Katayoun,
Shah, Omid,
Negrin, Robert S.,
Nagler, Arnon,
Prinz, Marco,
Burchert, Andreas,
Neubauer, Andreas,
Beelen, Dietrich,
Mackensen, Andreas,
von Bubnoff, Nikolas,
Herr, Wolfgang,
Becher, Burkhard,
Socié, Gerard,
Caligiuri, Michael A.,
Ruggiero, Eliana,
Bonini, Chiara,
Häcker, Georg,
Duyster, Justus,
Finke, Jürgen,
Pearce, Erika,
Blazar, Bruce R. und
Zeiser, Robert
(2018)
Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.
Nature Medicine 24 (3), S. 282-291.
Volltext nicht vorhanden.
2016
Knies, Diana,
Klobuch, Sebastian,
Xue, Shao-An,
Birtel, Matthias,
Echchannaoui, Hakim ,
Yildiz, Oezlem,
Omokoko, Tana,
Guillaume, Philippe,
Romero, Pedro ,
Stauss, Hans,
Sahin, Ugur ,
Herr, Wolfgang,
Theobald, Matthias,
Thomas, Simone und
Voss, Ralf-Holger
(2016)
An optimized single chain TCR scaffold relying on the assembly with the native CD3-complex prevents residual mispairing with endogenous TCRs in human T-cells.
Oncotarget 7 (16), S. 21199-21221.
Volltext nicht vorhanden.
2015
Nelson, Jay A. ,
Thomas, Simone,
Klobuch, Sebastian,
Podlech, Jürgen,
Plachter, Bodo,
Hoffmann, Petra,
Renzaho, Angelique,
Theobald, Matthias ,
Reddehase, Matthias J.,
Herr, Wolfgang und
Lemmermann, Niels A. W.
(2015)
Evaluating Human T-Cell Therapy of Cytomegalovirus Organ Disease in HLA-Transgenic Mice.
PLOS Pathogens 11 (7), e1005049.
Volltext nicht vorhanden.
Zupke, Oliver,
Distler, Eva,
Jürchott, Anna,
Paiphansiri, Umaporn,
Dass, Martin,
Thomas, Simone ,
Hartwig, Udo F ,
Theobald, Matthias,
Landfester, Katharina ,
Mailänder, Volker und
Herr, Wolfgang
(2015)
Nanoparticles and Antigen-Specific T-Cell Therapeutics: A Comprehensive Study on Uptake and Release.
Nanomedicine 10 (7), S. 1063-1076.
Volltext nicht vorhanden.
2014
Arens, Ramon,
Dörrie, Jan,
Krug, Christian,
Hofmann, Christian,
Müller, Ina,
Wellner, Verena,
Knippertz, Ilka,
Schierer, Stephan ,
Thomas, Simone,
Zipperer, Elke,
Printz, Dieter,
Fritsch, Gerhard,
Schuler, Gerold ,
Schaft, Niels und
Geyeregger, Rene
(2014)
Human Adenovirus-Specific γ/δ and CD8+ T Cells Generated by T-Cell Receptor Transfection to Treat Adenovirus Infection after Allogeneic Stem Cell Transplantation.
PLoS ONE 9 (10), e109944.
Volltext nicht vorhanden.
Thomas, Simone ,
Klobuch, Sebastian,
Sommer, Maria,
van Ewijk, Reyn,
Theobald, Matthias,
Meyer, Ralf G. und
Herr, Wolfgang
(2014)
Human CD8+ memory and EBV-specific T cells show low alloreactivity in vitro and in CD34+ stem cell–engrafted NOD/SCID/IL-2Rγcnull mice.
Experimental Hematology 42 (1), 28-38.e2.
Volltext nicht vorhanden.
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