Anzahl der Einträge: 14.
2019
Schramm, Simon,
Agnetta, Luca,
Bermudez, Marcel,
Gerwe, Hubert,
Irmen, Matthias,
Holze, Janine,
Littmann, Timo,
Wolber, Gerhard ,
Tränkle, Christian und
Decker, Michael
(2019)
Novel BQCA‐ and TBPB‐Derived M 1 Receptor Hybrid Ligands: Orthosteric Carbachol Differentially Regulates Partial Agonism.
ChemMedChem 14 (14), S. 1349-1358.
Volltext nicht vorhanden.
Agnetta, Luca,
Bermudez, Marcel ,
Riefolo, Fabio ,
Matera, Carlo ,
Claro, Enrique ,
Messerer, Regina,
Littmann, Timo,
Wolber, Gerhard ,
Holzgrabe, Ulrike und
Decker, Michael
(2019)
Fluorination of Photoswitchable Muscarinic Agonists Tunes Receptor Pharmacology and Photochromic Properties.
Journal of Medicinal Chemistry 62 (6), S. 3009-3020.
Volltext nicht vorhanden.
2018
Dolles, Dominik,
Hoffmann, Matthias,
Gunesch, Sandra,
Marinelli, Oliviero,
Möller, Jan ,
Santoni, Giorgio,
Chatonnet, Arnaud,
Lohse, Martin J. ,
Wittmann, Hans-Joachim,
Strasser, Andrea,
Nabissi, Massimo,
Maurice, Tangui und
Decker, Michael
(2018)
Structure–Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles.
Journal of Medicinal Chemistry 61 (4), S. 1646-1663.
Volltext nicht vorhanden.
2017
Huang, Guozheng ,
Drakopoulos, Antonios ,
Saedtler, Marco,
Zou, Huijuan,
Meinel, Lorenz ,
Heilmann, Jörg und
Decker, Michael
(2017)
Cytotoxic properties of the alkaloid rutaecarpine and its oligocyclic derivatives and chemical modifications to enhance water-solubility.
Bioorganic & Medicinal Chemistry Letters 27 (21), S. 4937-4941.
Volltext nicht vorhanden.
2016
Dolles, Dominik,
Nimczick, Martin,
Scheiner, Matthias,
Ramler, Jacqueline,
Stadtmüller, Patricia,
Sawatzky, Edgar,
Drakopoulos, Antonios,
Sotriffer, Christoph,
Wittmann, Hans-Joachim,
Strasser, Andrea und
Decker, Michael
(2016)
Aminobenzimidazoles and structural isomers as templates for dual-acting butyrylcholinesterase inhibitors and hCB2R ligands to combat neurodegenerative disorders.
ChemMedChem 11 (12), S. 1270-1283.
Volltext nicht vorhanden.
Sawatzky, Edgar,
Wehle, Sarah,
Kling, Beata,
Wendrich, Jan,
Bringmann, Gerhard,
Sotriffer, Christoph A.,
Heilmann, Jörg und
Decker, Michael
(2016)
Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode.
Journal of Medicinal Chemistry 59 (5), S. 2067-2082.
Volltext nicht vorhanden.
Khan, Nadia,
Saad, Ali,
Nurulain, Syed M.,
Darras, Fouad H.,
Decker, Michael und
Sadek, Bassem
(2016)
The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats.
Behavioural Brain Research 297, S. 155-164.
Volltext nicht vorhanden.
Huang, Guozheng ,
Schramm, Simon,
Heilmann, Jörg,
Biedermann, David,
Křen, Vladimír und
Decker, Michael
(2016)
Unconventional application of the Mitsunobu reaction: Selective flavonolignan dehydration yielding hydnocarpins.
Beilstein Journal of Organic Chemistry 12, S. 662-669.
Volltext nicht vorhanden.
2015
Dolles, Dominik,
Nimczick, Martin,
Scheiner, Matthias,
Ramler, Jacqueline,
Stadtmüller, Patricia,
Sawatzky, Edgar,
Drakopoulos, Antonios ,
Sotriffer, Christoph,
Wittmann, Hans-Joachim,
Strasser, Andrea und
Decker, Michael
(2015)
Aminobenzimidazoles and Structural Isomers as Templates for Dual-Acting Butyrylcholinesterase Inhibitors andhCB2R Ligands To Combat Neurodegenerative Disorders.
ChemMedChem 11 (12), S. 1270-1283.
Volltext nicht vorhanden.
2014
Darras, Fouad,
Pockes, Steffen ,
Huang, Guozheng,
Wehle, Sarah,
Strasser, Andrea,
Wittmann, Hans-Joachim,
Nimczick, Martin,
Sotriffer, Christoph und
Decker, Michael
(2014)
Synthesis, biological evaluation, and computational studies of tri- and tetracyclic nitrogen-bridgehead compounds as potent dual-acting AChE inhibitors and hH3 receptor antagonists.
ACS Chemical Neuroscience 5 (3), S. 225-242.
Volltext nicht vorhanden.
Chen, Xinyu,
Wehle, Sarah,
Kuzmanovic, Natascha,
Merget, Benjamin,
Holzgrabe, Ulrike,
König, Burkhard,
Sotriffer, Christoph A. und
Decker, Michael
(2014)
Acetylcholinesterase Inhibitors with Photoswitchable Inhibition of β‑Amyloid Aggregation.
ACS Chemical Neuroscience 5, S. 377-389.
Volltext nicht vorhanden.
2008
Fang, Lei,
Kraus, Birgit,
Lehmann, Jochen,
Heilmann, Jörg,
Zhang, Yihua und
Decker, Michael
(2008)
Design and synthesis of tacrine-ferulic acid hybrids as multi-potent anti-Alzheimer drug candidates.
Bioorganic & medicinal chemistry letters 18 (9), S. 2905-2909.
Volltext nicht vorhanden.
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