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Anzahl der Einträge: 14.
Artikel
Schramm, Simon, Agnetta, Luca, Bermudez, Marcel, Gerwe, Hubert, Irmen, Matthias, Holze, Janine, Littmann, Timo, Wolber, Gerhard 
, Tränkle, Christian und Decker, Michael
(2019)
Novel BQCA‐ and TBPB‐Derived M 1 Receptor Hybrid Ligands: Orthosteric Carbachol Differentially Regulates Partial Agonism.
ChemMedChem 14 (14), S. 1349-1358.
Volltext nicht vorhanden.
, Tränkle, Christian und Decker, Michael
(2019)
Novel BQCA‐ and TBPB‐Derived M 1 Receptor Hybrid Ligands: Orthosteric Carbachol Differentially Regulates Partial Agonism.
ChemMedChem 14 (14), S. 1349-1358.
Volltext nicht vorhanden.
Agnetta, Luca, Bermudez, Marcel , Riefolo, Fabio , Matera, Carlo , Claro, Enrique , Messerer, Regina, Littmann, Timo, Wolber, Gerhard , Holzgrabe, Ulrike und Decker, Michael
(2019)
Fluorination of Photoswitchable Muscarinic Agonists Tunes Receptor Pharmacology and Photochromic Properties.
Journal of Medicinal Chemistry 62 (6), S. 3009-3020.
Volltext nicht vorhanden.
, Riefolo, Fabio , Matera, Carlo , Claro, Enrique , Messerer, Regina, Littmann, Timo, Wolber, Gerhard , Holzgrabe, Ulrike und Decker, Michael
(2019)
Fluorination of Photoswitchable Muscarinic Agonists Tunes Receptor Pharmacology and Photochromic Properties.
Journal of Medicinal Chemistry 62 (6), S. 3009-3020.
Volltext nicht vorhanden.
Dolles, Dominik, Hoffmann, Matthias, Gunesch, Sandra, Marinelli, Oliviero, Möller, Jan , Santoni, Giorgio, Chatonnet, Arnaud, Lohse, Martin J. , Wittmann, Hans-Joachim, Strasser, Andrea, Nabissi, Massimo, Maurice, Tangui und Decker, Michael
(2018)
Structure–Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles.
Journal of Medicinal Chemistry 61 (4), S. 1646-1663.
Volltext nicht vorhanden.
, Santoni, Giorgio, Chatonnet, Arnaud, Lohse, Martin J. , Wittmann, Hans-Joachim, Strasser, Andrea, Nabissi, Massimo, Maurice, Tangui und Decker, Michael
(2018)
Structure–Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles.
Journal of Medicinal Chemistry 61 (4), S. 1646-1663.
Volltext nicht vorhanden.
Huang, Guozheng , Drakopoulos, Antonios , Saedtler, Marco, Zou, Huijuan, Meinel, Lorenz , Heilmann, Jörg und Decker, Michael
(2017)
Cytotoxic properties of the alkaloid rutaecarpine and its oligocyclic derivatives and chemical modifications to enhance water-solubility.
Bioorganic & Medicinal Chemistry Letters 27 (21), S. 4937-4941.
Volltext nicht vorhanden.
, Drakopoulos, Antonios , Saedtler, Marco, Zou, Huijuan, Meinel, Lorenz , Heilmann, Jörg und Decker, Michael
(2017)
Cytotoxic properties of the alkaloid rutaecarpine and its oligocyclic derivatives and chemical modifications to enhance water-solubility.
Bioorganic & Medicinal Chemistry Letters 27 (21), S. 4937-4941.
Volltext nicht vorhanden.
Sadek, Bassem, Khan, Nadia, Darras, Fouad H., Pockes, Steffen und Decker, Michael
(2016)
The dual-acting AChE inhibitor and H3 receptor antagonist UW-MD-72 reverses amnesia induced by scopolamine or dizocilpine in passive avoidance paradigm in rats.
Physiology & Behavior 165, S. 383-391.
Volltext nicht vorhanden.
und Decker, Michael
(2016)
The dual-acting AChE inhibitor and H3 receptor antagonist UW-MD-72 reverses amnesia induced by scopolamine or dizocilpine in passive avoidance paradigm in rats.
Physiology & Behavior 165, S. 383-391.
Volltext nicht vorhanden.
Dolles, Dominik, Nimczick, Martin, Scheiner, Matthias, Ramler, Jacqueline, Stadtmüller, Patricia, Sawatzky, Edgar, Drakopoulos, Antonios, Sotriffer, Christoph, Wittmann, Hans-Joachim, Strasser, Andrea und Decker, Michael
(2016)
Aminobenzimidazoles and structural isomers as templates for dual-acting butyrylcholinesterase inhibitors and hCB2R ligands to combat neurodegenerative disorders.
ChemMedChem 11 (12), S. 1270-1283.
Volltext nicht vorhanden.
Sawatzky, Edgar, Wehle, Sarah, Kling, Beata, Wendrich, Jan, Bringmann, Gerhard, Sotriffer, Christoph A., Heilmann, Jörg und Decker, Michael
(2016)
Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode.
Journal of Medicinal Chemistry 59 (5), S. 2067-2082.
Volltext nicht vorhanden.
Khan, Nadia, Saad, Ali, Nurulain, Syed M., Darras, Fouad H., Decker, Michael und Sadek, Bassem
(2016)
The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats.
Behavioural Brain Research 297, S. 155-164.
Volltext nicht vorhanden.
Huang, Guozheng , Schramm, Simon, Heilmann, Jörg, Biedermann, David, Křen, Vladimír und Decker, Michael
(2016)
Unconventional application of the Mitsunobu reaction: Selective flavonolignan dehydration yielding hydnocarpins.
Beilstein Journal of Organic Chemistry 12, S. 662-669.
Volltext nicht vorhanden.
, Schramm, Simon, Heilmann, Jörg, Biedermann, David, Křen, Vladimír und Decker, Michael
(2016)
Unconventional application of the Mitsunobu reaction: Selective flavonolignan dehydration yielding hydnocarpins.
Beilstein Journal of Organic Chemistry 12, S. 662-669.
Volltext nicht vorhanden.
Dolles, Dominik, Nimczick, Martin, Scheiner, Matthias, Ramler, Jacqueline, Stadtmüller, Patricia, Sawatzky, Edgar, Drakopoulos, Antonios , Sotriffer, Christoph, Wittmann, Hans-Joachim, Strasser, Andrea und Decker, Michael
(2015)
Aminobenzimidazoles and Structural Isomers as Templates for Dual-Acting Butyrylcholinesterase Inhibitors andhCB2R Ligands To Combat Neurodegenerative Disorders.
ChemMedChem 11 (12), S. 1270-1283.
Volltext nicht vorhanden.
, Sotriffer, Christoph, Wittmann, Hans-Joachim, Strasser, Andrea und Decker, Michael
(2015)
Aminobenzimidazoles and Structural Isomers as Templates for Dual-Acting Butyrylcholinesterase Inhibitors andhCB2R Ligands To Combat Neurodegenerative Disorders.
ChemMedChem 11 (12), S. 1270-1283.
Volltext nicht vorhanden.
Darras, Fouad, Pockes, Steffen , Huang, Guozheng, Wehle, Sarah, Strasser, Andrea, Wittmann, Hans-Joachim, Nimczick, Martin, Sotriffer, Christoph und Decker, Michael
(2014)
Synthesis, biological evaluation, and computational studies of tri- and tetracyclic nitrogen-bridgehead compounds as potent dual-acting AChE inhibitors and hH3 receptor antagonists.
ACS Chemical Neuroscience 5 (3), S. 225-242.
Volltext nicht vorhanden.
, Huang, Guozheng, Wehle, Sarah, Strasser, Andrea, Wittmann, Hans-Joachim, Nimczick, Martin, Sotriffer, Christoph und Decker, Michael
(2014)
Synthesis, biological evaluation, and computational studies of tri- and tetracyclic nitrogen-bridgehead compounds as potent dual-acting AChE inhibitors and hH3 receptor antagonists.
ACS Chemical Neuroscience 5 (3), S. 225-242.
Volltext nicht vorhanden.
Chen, Xinyu, Wehle, Sarah, Kuzmanovic, Natascha, Merget, Benjamin, Holzgrabe, Ulrike, König, Burkhard, Sotriffer, Christoph A. und Decker, Michael
(2014)
Acetylcholinesterase Inhibitors with Photoswitchable Inhibition of β‑Amyloid Aggregation.
ACS Chemical Neuroscience 5, S. 377-389.
Volltext nicht vorhanden.
Fang, Lei, Kraus, Birgit, Lehmann, Jochen, Heilmann, Jörg, Zhang, Yihua und Decker, Michael
(2008)
Design and synthesis of tacrine-ferulic acid hybrids as multi-potent anti-Alzheimer drug candidates.
Bioorganic & medicinal chemistry letters 18 (9), S. 2905-2909.
Volltext nicht vorhanden.
Decker, Michael, Kraus, Birgit und Heilmann, Jörg
(2008)
Design, synthesis and pharmacological evaluation of hybrid molecules out of quinazolinimines and lipoic acid lead to highly potent and selective butyrylcholinesterase inhibitors with antioxidant properties.
Bioorganic & medicinal chemistry 16 (8), S. 4252-4261.
Volltext nicht vorhanden.
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