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Einträge von Lebek, Simon auf dem Publikationsserver
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Anzahl der Einträge: 31.
2025
Seydel, Bettina, Hegner, Philipp 
, Lauerer, Anna-Maria, Schildt, Sönke, Bayram, Fatma, Tafelmeier, Maria , Wermers, Dominik, Rupprecht, Leopold , Schmid, Christof, Wagner, Stefan , Maier, Lars Siegfried , Arzt, Michael und Lebek, Simon
(2025)
Increased Myocardial MARK4 Expression in Patients with Heart Failure and Sleep-Disordered Breathing.
International Journal of Molecular Sciences 26 (8), S. 3614.
Bayram, Fatma, Hegner, Philipp , Lauerer, Anna-Maria, Schildt, Sönke, Wermers, Dominik, Baier, Maria Johanna, Mustroph, Julian , Tafelmeier, Maria , Provaznik, Zdenek , Schmid, Christof, Maier, Lars Siegfried , Wagner, Stefan , Arzt, Michael und Lebek, Simon
(2025)
Myocardial DYRK1B Expression Is Increased in Patients with Impaired Cardiac Contractility and Sleep-Disordered Breathing.
Antioxidants 14 (2), S. 163.
2024
Lauerer, Anna-Maria, Caravia, Xurde M., Maier, Lars S., Chemello, Francesco und Lebek, Simon
(2024)
Gene editing in common cardiovascular diseases.
Pharmacology & Therapeutics 263, S. 108720.
Hegner, Philipp , Ofner, Florian, Schaner, Benedikt, Gugg, Mathias, Trum, Maximilian , Lauerer, Anna-Maria, Maier, Lars Siegfried , Arzt, Michael , Lebek, Simon und Wagner, Stefan
(2024)
CaMKIIδ-dependent dysregulation of atrial Na+ homeostasis promotes pro-arrhythmic activity in an obstructive sleep apnea mouse model.
Frontiers in Pharmacology 15.
Hegner, Philipp , Wester, Michael , Tafelmeier, Maria , Provaznik, Zdenek , Klatt, Susanne, Schmid, Christof, Maier, Lars Siegfried , Arzt, Michael , Wagner, Stefan und Lebek, Simon
(2024)
Systemic inflammation predicts diastolic dysfunction in patients with sleep disordered breathing.
European Respiratory Journal 63 (6), S. 2400579.
Trum, Maximilian , Riechel, Johannes, Schollmeier, Elisa, Lebek, Simon , Hegner, Philipp , Reuthner, Kathrin, Heers, Silvia, Keller, Karoline, Wester, Michael , Klatt, Susanne, Hamdani, Nazha, Provaznik, Zdenek , Schmid, Christof, Maier, Lars S. , Arzt, Michael und Wagner, Stefan
(2024)
Empagliflozin inhibits increased Na influx in atrial cardiomyocytes of patients with HFpEF.
Cardiovascular Research.
2023
Wester, Michael, Arzt, Michael, Sinha, Frederick, Maier, Lars S. und Lebek, Simon
(2023)
Insights into the Interaction of Heart Failure with Preserved Ejection Fraction and Sleep-Disordered Breathing.
Biomedicines 11 (11), S. 3038.
Hegner, Philipp , Lebek, Simon , Schaner, Benedikt, Ofner, Florian, Gugg, Mathias, Maier, Lars Siegfried, Arzt, Michael und Wagner, Stefan
(2023)
CaMKII-Dependent Contractile Dysfunction and Pro-Arrhythmic Activity in a Mouse Model of Obstructive Sleep Apnea.
Antioxidants 12 (2), S. 315.
Mustroph, Julian, Baier, Maria J., Unsin, Denise, Provaznik, Zdenek, Kozakov, Kostiantyn, Lebek, Simon , Tarnowski, Daniel, Schildt, Sönke , Voigt, Niels, Wagner, Stefan , Maier, Lars S. und Neef, Stefan
(2023)
Ethanol-Induced Atrial Fibrillation Results From Late I Na and Can Be Prevented by Ranolazine.
Circulation 148 (8), S. 698-700.
Volltext nicht vorhanden.
, Tarnowski, Daniel, Schildt, Sönke , Voigt, Niels, Wagner, Stefan , Maier, Lars S. und Neef, Stefan
(2023)
Ethanol-Induced Atrial Fibrillation Results From Late I Na and Can Be Prevented by Ranolazine.
Circulation 148 (8), S. 698-700.
Volltext nicht vorhanden.
Lebek, Simon , Chemello, Francesco , Caravia, Xurde M., Tan, Wei, Li, Hui, Chen, Kenian, Xu, Lin , Liu, Ning , Bassel-Duby, Rhonda und Olson, Eric N.
(2023)
Ablation of CaMKIIδ oxidation by CRISPR-Cas9 base editing as a therapy for cardiac disease.
Science 379 (6628), S. 179-185.
Volltext nicht vorhanden.
, Chemello, Francesco , Caravia, Xurde M., Tan, Wei, Li, Hui, Chen, Kenian, Xu, Lin , Liu, Ning , Bassel-Duby, Rhonda und Olson, Eric N.
(2023)
Ablation of CaMKIIδ oxidation by CRISPR-Cas9 base editing as a therapy for cardiac disease.
Science 379 (6628), S. 179-185.
Volltext nicht vorhanden.
Lebek, Simon , Caravia, Xurde M., Chemello, Francesco, Tan, Wei, McAnally, John R., Chen, Kenian, Xu, Lin, Liu, Ning, Bassel-Duby, Rhonda und Olson, Eric N.
(2023)
Elimination of CaMKIIδ Autophosphorylation by CRISPR-Cas9 Base Editing Improves Survival and Cardiac Function in Heart Failure in Mice.
Circulation 148 (19), S. 1490-1504.
Volltext nicht vorhanden.
, Caravia, Xurde M., Chemello, Francesco, Tan, Wei, McAnally, John R., Chen, Kenian, Xu, Lin, Liu, Ning, Bassel-Duby, Rhonda und Olson, Eric N.
(2023)
Elimination of CaMKIIδ Autophosphorylation by CRISPR-Cas9 Base Editing Improves Survival and Cardiac Function in Heart Failure in Mice.
Circulation 148 (19), S. 1490-1504.
Volltext nicht vorhanden.
2022
Lebek, Simon , Hegner, Philipp , Hultsch, Rosa, Rohde, Jonas, Rupprecht, Leopold, Schmid, Christof, Sossalla, Samuel, Maier, Lars Siegfried, Arzt, Michael und Wagner, Stefan
(2022)
Voltage-Gated Sodium Channel NaV1.8 Dysregulates Na and Ca, Leading to Arrhythmias in Patients with Sleep-Disordered Breathing.
American Journal of Respiratory and Critical Care Medicine 206 (11).
Zugang zum Volltext eingeschränkt.
, Hegner, Philipp , Hultsch, Rosa, Rohde, Jonas, Rupprecht, Leopold, Schmid, Christof, Sossalla, Samuel, Maier, Lars Siegfried, Arzt, Michael und Wagner, Stefan
(2022)
Voltage-Gated Sodium Channel NaV1.8 Dysregulates Na and Ca, Leading to Arrhythmias in Patients with Sleep-Disordered Breathing.
American Journal of Respiratory and Critical Care Medicine 206 (11).
Zugang zum Volltext eingeschränkt.
Lebek, Simon , Hegner, Philipp, Hultsch, Rosa, Rohde, Jonas, Rupprecht, Leopold , Schmid, Christof, Sossalla, Samuel , Maier, Lars Siegfried , Arzt, Michael und Wagner, Stefan
(2022)
Supplemental Material for "NaV1.8 dysregulates Na and Ca leading to arrhythmias in patients with sleep-disordered breathing".
(Unveröffentlicht)
Zugang zum Volltext eingeschränkt.
, Hegner, Philipp, Hultsch, Rosa, Rohde, Jonas, Rupprecht, Leopold , Schmid, Christof, Sossalla, Samuel , Maier, Lars Siegfried , Arzt, Michael und Wagner, Stefan
(2022)
Supplemental Material for "NaV1.8 dysregulates Na and Ca leading to arrhythmias in patients with sleep-disordered breathing".
(Unveröffentlicht)
Zugang zum Volltext eingeschränkt.
Wester, Michael, Pec, Jan , Lebek, Simon , Fisser, Christoph, Debl, Kurt, Hamer, Okka W., Poschenrieder, Florian, Buchner, Stefan, Maier, Lars S., Arzt, Michael und Wagner, Stefan
(2022)
Sleep-Disordered Breathing Is Associated With Reduced Left Atrial Strain Measured by Cardiac Magnetic Resonance Imaging in Patients After Acute Myocardial Infarction.
Frontiers in Medicine 2022 (9), S. 759361.
Arzt, Michael, Drzymalski, Marzena A., Ripfel, Sarah, Meindl, Sebastian, Biedermann, Alexander, Durczok, Melanie, Keller, Karoline, Mustroph, Julian, Katz, Sylvia, Tafelmeier, Maria, Lebek, Simon , Flörchinger, Bernhard, Camboni, Daniele, Wittmann, Sigrid, Backs, Johannes, Schmid, Christof, Maier, Lars S. und Wagner, Stefan
(2022)
Enhanced Cardiac CaMKII Oxidation and CaMKII-Dependent SR Ca Leak in Patients with Sleep-Disordered Breathing.
Antioxidants 11 (2), S. 331.
2021
Islam, M. M. Towhidul, Tarnowski, Daniel, Zhang, Min , Trum, Maximilian , Lebek, Simon, Mustroph, Julian, Daniel, Henriette, Moellencamp, Johanna, Pabel, Steffen, Sossalla, Samuel, El‐Armouche, Ali, Nikolaev, Viacheslav O., Shah, Ajay M., Eaton, Philip J. , Maier, Lars S., Sag, Can Martin und Wagner, Stefan
(2021)
Enhanced Heart Failure in Redox‐Dead Cys17Ser PKARIα Knock‐In Mice.
Journal of the American Heart Association 10 (19), 021985.
Hegner, Philipp, Lebek, Simon, Maier, Lars Siegfried, Arzt, Michael und Wagner, Stefan
(2021)
The Effect of Gender and Sex Hormones on Cardiovascular Disease, Heart Failure, Diabetes, and Atrial Fibrillation in Sleep Apnea.
Frontiers in Physiology 2121 (12), S. 1-8.
Lebek, Simon , Wester, Michael , Pec, Jan, Poschenrieder, Florian, Tafelmeier, Maria, Fisser, Christoph, Provaznik, Zdenek, Schopka, Simon, Debl, Kurt, Schmid, Christof, Buchner, Stefan, Maier, Lars S., Arzt, Michael und Wagner, Stefan
(2021)
Abnormal P‐wave terminal force in lead V 1 is a marker for atrial electrical dysfunction but not structural remodelling.
ESC Heart Failure 8 (5), S. 4055-4066.
Wagner, Stefan, Lebek, Simon, Hegner, Philipp, Tafelmeier, Maria, Rupprecht, Leopold, Schmid, Christof, Maier, Lars Siegfried und Arzt, Michael
(2021)
Female Patients With Sleep-Disordered Breathing Display More Frequently Heart Failure With Preserved Ejection Fraction.
Medicine 2021 (8), S. 675987.
(Eingereicht)
Hegner, Philipp, Lebek, Simon, Tafelmeier, Maria, Camboni, Daniele, Schopka, Simon, Schmid, Christof, Maier, Lars Siegfried, Arzt, Michael und Wagner, Stefan
(2021)
Sleep-disordered breathing is independently associated with reduced atrial connexin 43 expression.
Heart Rhythm 18 (12), S. 2187-2194.
Volltext nicht vorhanden.
2020
Lebek, Simon, Hegner, Philipp, Schach, Christian, Reuthner, Katrin, Tafelmeier, Maria , Maier, Lars S., Arzt, Michael und Wagner, Stefan
(2020)
A novel mouse model of obstructive sleep apnea by bulking agent-induced tongue enlargement results in left ventricular contractile dysfunction.
PLoS One 15 (12), e0243844.
(Im Druck)
Lebek, Simon, Tafelmeier, Maria, Messmann, Rebecca, Provaznik, Zdenek, Schmid, Christof, Maier, Lars S., Birner, Christoph, Arzt, Michael und Wagner, Stefan
(2020)
Angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker treatment and haemodynamic factors are associated with increased cardiac mRNA expression of angiotensin-converting enzyme 2 in patients with cardiovascular disease.
European Journal of Heart Failure 22, S. 2248-2257.
Trum, Maximilian , Riechel, Johannes, Lebek, Simon, Pabel, Steffen, Sossalla, Samuel T., Hirt, Stephan, Arzt, Michael, Maier, Lars S. und Wagner, Stefan
(2020)
Empagliflozin inhibits Na + /H + exchanger activity in human atrial cardiomyocytes.
ESC Heart Failure 2020, S. 1-9.
Trum, Maximilian, Islam, Towhidul, Lebek, Simon, Baier, Maria, Hegner, Philipp, Eaton, Phil, Maier, Lars Siegfried und Wagner, Stefan
(2020)
Supplemental Figures S1 and S2.
[Bild]
(Eingereicht)
Lebek, Simon, Pichler, Konstantin, Reuthner, Kathrin, Trum, Maximillian, Tafelmeier, Maria, Mustroph, Julian , Camboni, Daniele, Rupprecht, Leopold, Schmid, Christof, Maier, Lars S., Arzt, Michael und Wagner, Stefan
(2020)
Enhanced CaMKII-Dependent Late I Na Induces Atrial Proarrhythmic Activity in Patients With Sleep-Disordered Breathing.
Circulation Research 126 (5), S. 603-615.
Volltext nicht vorhanden.
, Camboni, Daniele, Rupprecht, Leopold, Schmid, Christof, Maier, Lars S., Arzt, Michael und Wagner, Stefan
(2020)
Enhanced CaMKII-Dependent Late I Na Induces Atrial Proarrhythmic Activity in Patients With Sleep-Disordered Breathing.
Circulation Research 126 (5), S. 603-615.
Volltext nicht vorhanden.
Bader, Michael, Lebek, Simon, Hegner, Philipp, Schach, Christian, Reuthner, Kathrin, Tafelmeier, Maria, Maier, Lars Siegfried, Arzt, Michael und Wagner, Stefan
(2020)
A novel mouse model of obstructive sleep apnea by bulking agent-induced tongue enlargement results in left ventricular contractile dysfunction.
PLOS ONE 15 (12), e0243844.
Volltext nicht vorhanden.
Sossalla, Samuel, Maier, Lars S. , Neef, Stefan, Wagner, Stefan, Rupprecht, Leopold, Keyser, Andreas, Dybkova, Nataliya, Lebek, Simon, Stehle, Thea, Mustroph, Julian und Pabel, Steffen
(2020)
Dantrolene reduces CaMKIIδC-mediated atrial arrhythmias.
EP Europace 22 (7), S. 1111-1118.
Volltext nicht vorhanden.
, Neef, Stefan, Wagner, Stefan, Rupprecht, Leopold, Keyser, Andreas, Dybkova, Nataliya, Lebek, Simon, Stehle, Thea, Mustroph, Julian und Pabel, Steffen
(2020)
Dantrolene reduces CaMKIIδC-mediated atrial arrhythmias.
EP Europace 22 (7), S. 1111-1118.
Volltext nicht vorhanden.
2019
Tafelmeier, Maria, Knapp, Marvin, Lebek, Simon, Floerchinger, Bernhard, Camboni, Daniele, Creutzenberg, Marcus, Wittmann, Sigrid, Zeman, Florian, Schmid, Christof, Maier, Lars Siegfried, Wagner, Stefan und Arzt, Michael
(2019)
Predictors of delirium after cardiac surgery in patients with sleep disordered breathing.
European Respiratory Journal 54 (2), S. 1900354.
Volltext nicht vorhanden.
2018
Mustroph, Julian, Wagemann, Olivia, Lücht, Charlotte M., Trum, Maximilian, Hammer, Karin P., Sag, Can Martin, Lebek, Simon, Tarnowski, Daniel, Reinders, Jörg, Perbellini, Filippo, Terracciano, Cesare, Schmid, Christof, Schopka, Simon, Hilker, Michael, Zausig, York, Pabel, Steffen, Sossalla, Samuel T., Schweda, Frank, Maier, Lars S. und Wagner, Stefan
(2018)
Empagliflozin reduces Ca/calmodulin-dependent kinase II activity in isolated ventricular cardiomyocytes.
ESC Heart Failure 5 (4), S. 642-648.
Neef, Stefan, Steffens, Alexander, Pellicena, Patricia, Mustroph, Julian, Lebek, Simon, Ort, Katharina R., Schulman, Howard und Maier, Lars S.
(2018)
Improvement of cardiomyocyte function by a novel pyrimidine-based CaMKII-inhibitor.
Journal of Molecular and Cellular Cardiology 115, S. 73-81.
Volltext nicht vorhanden.
Mustroph, Julian, Wagemann, Olivia, Lebek, Simon, Tarnowski, Daniel, Ackermann, Jasmin, Drzymalski, Marzena, Pabel, Steffen, Schmid, Christof, Wagner, Stefan , Sossalla, Samuel, Maier, Lars S. und Neef, Stefan
(2018)
SR Ca 2+ -leak and disordered excitation-contraction coupling as the basis for arrhythmogenic and negative inotropic effects of acute ethanol exposure.
Journal of Molecular and Cellular Cardiology 116, S. 81-90.
Volltext nicht vorhanden.
, Sossalla, Samuel, Maier, Lars S. und Neef, Stefan
(2018)
SR Ca 2+ -leak and disordered excitation-contraction coupling as the basis for arrhythmogenic and negative inotropic effects of acute ethanol exposure.
Journal of Molecular and Cellular Cardiology 116, S. 81-90.
Volltext nicht vorhanden.
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