Einträge von Littmann, Timo auf dem Publikationsserver

Grätz, Lukas, Müller, Christoph, Pegoli, Andrea , Schindler, Lisa, Bernhardt, Günther und Littmann, Timo (2022) Insertion of Nanoluc into the Extracellular Loops as a Complementary Method To Establish BRET-Based Binding Assays for GPCRs. ACS Pharmacology & Translational Science 5 (11), S. 1142-1155.

Tropmann, Katharina, Seibel-Ehlert, Ulla, Littmann, Timo und Strasser, Andrea (2021) Shining light on the histamine H2 receptor: Synthesis of carbamoylguanidine-type agonists as a pharmacological tool to study internalization. Bioorganic & Medicinal Chemistry Letters 52, S. 128388. Volltext nicht vorhanden.

Bartole, Edith, Grätz, Lukas, Littmann, Timo, Wifling, David , Seibel, Ulla, Buschauer, Armin und Bernhardt, Günther (2020) UR-DEBa242: A Py-5-Labeled Fluorescent Multipurpose Probe for Investigations on the Histamine H3 and H4 Receptors. Journal of Medicinal Chemistry 63 (10), S. 5297-5311. Volltext nicht vorhanden.

Keller, Max, Mahuroof, Shahani A., Hong Yee, Vivyanne, Carpenter, Jessica, Schindler, Lisa, Littmann, Timo, Pegoli, Andrea, Hübner, Harald, Bernhardt, Günther, Gmeiner, Peter und Holliday, Nicholas D. (2020) Fluorescence Labeling of Neurotensin(8–13) via Arginine Residues Gives Molecular Tools with High Receptor Affinity. ACS Medicinal Chemistry Letters 11 (1), S. 16-22. Volltext nicht vorhanden.

Biselli, Sabrina, Alencastre, Inês, Tropmann, Katharina, Erdmann, Daniela, Chen, Mengya, Littmann, Timo, Maia, André F. , Gomez-Lazaro, Maria, Tanaka, Miho, Ozawa, Takeaki, Keller, Max, Lamghari, Meriem, Buschauer, Armin und Bernhardt, Günther (2020) Fluorescent H2 Receptor Squaramide-Type Antagonists: Synthesis, Characterization, and Applications. ACS Medicinal Chemistry Letters 11 (8), S. 1521-1528. Volltext nicht vorhanden.

Schramm, Simon, Agnetta, Luca, Bermudez, Marcel, Gerwe, Hubert, Irmen, Matthias, Holze, Janine, Littmann, Timo, Wolber, Gerhard , Tränkle, Christian und Decker, Michael (2019) Novel BQCA‐ and TBPB‐Derived M 1 Receptor Hybrid Ligands: Orthosteric Carbachol Differentially Regulates Partial Agonism. ChemMedChem 14 (14), S. 1349-1358. Volltext nicht vorhanden.

Agnetta, Luca, Bermudez, Marcel , Riefolo, Fabio , Matera, Carlo , Claro, Enrique , Messerer, Regina, Littmann, Timo, Wolber, Gerhard , Holzgrabe, Ulrike und Decker, Michael (2019) Fluorination of Photoswitchable Muscarinic Agonists Tunes Receptor Pharmacology and Photochromic Properties. Journal of Medicinal Chemistry 62 (6), S. 3009-3020. Volltext nicht vorhanden.

Littmann, Timo, Buschauer, Armin und Bernhardt, Günther (2019) Split luciferase-based assay for simultaneous analyses of the ligand concentration- and time-dependent recruitment of β-arrestin2. Analytical Biochemistry 573, S. 8-16. Volltext nicht vorhanden.

Bartole, Edith, Littmann, Timo, Tanaka, Miho, Ozawa, Takeaki, Buschauer, Armin und Bernhardt, Günther (2019) [3H]UR-DEBa176: A 2,4-Diaminopyrimidine-Type Radioligand Enabling Binding Studies at the Human, Mouse, and Rat Histamine H4 Receptors. Journal of Medicinal Chemistry 62 (17), S. 8338-8356. Volltext nicht vorhanden.

Littmann, Timo, Ozawa, Takeaki, Hoffmann, Carsten, Buschauer, Armin und Bernhardt, Günther (2018) A split luciferase-based probe for quantitative proximal determination of Gαq signalling in live cells. Scientific Reports 8 (17179), S. 1-10.

Yang, Zhenlin, Han, Shuo, Keller, Max, Kaiser, Anette, Bender, Brain J., Bosse, Mathias, Burkert, Kerstin, Kögler, Lisa M., Wifling, David , Bernhardt, Günther, Plank, Nicole, Littmann, Timo, Schmidt, Peter, Yi, Cuiying, Li, Beibei, Ye, Sheng, Zhang, Rongguang, Xu, Bo, Larhammar, Dan, Stevens, Raymond C. , Huster, Daniel, Meiler, Jens, Zhao, Qiang, Beck-Sickinger, Annette G., Buschauer, Armin und Wu, Beili (2018) Structural basis of ligand binding modes at the
neuropeptide Y Y1 receptor. Nature 556, S. 520-524. Volltext nicht vorhanden.

Schramm, Andrea, Mueller-Thuemen, Philip, Littmann, Timo, Harloff, Manuela, Ozawa, Takeaki und Schlossmann, Jens (2018) Establishing a Split Luciferase Assay for Proteinkinase G (PKG) Interaction Studies. International Journal o f Molecular Sciences 19 (4), S. 1180.

Littmann, Timo, Ozawa, Takeaki, Hoffmann, Carsten, Buschauer, Armin und Bernhardt, Günther (2018) A split luciferase-based probe for quantitative proximal determination of Gαq signalling in live cells. Scientific Reports 8 (1), S. 17179.

Dukorn, Stefanie, Littmann, Timo, Keller, Max, Kuhn, Kilian K., Cabrele, Chiara , Baumeister, Paul, Bernhardt, Günther und Buschauer, Armin (2017) Fluorescence- and radio-labeling of Lys4,Nle17,30hPP yields molecular tools for the NPY Y4 receptor. Bioconjugate Chemistry. Volltext nicht vorhanden.

Kuhn, Kilian K., Littmann, Timo, Dukorn, Stefanie, Tanaka, Miho, Keller, Max, Ozawa, Takeaki, Bernhardt, Günther und Buschauer, Armin (2017) In Search of NPY Y4R Antagonists: Incorporation of Carbamoylated Arginine, Aza-Amino Acids, or d-Amino Acids into Oligopeptides Derived from the C-Termini of the Endogenous Agonists. ACS Omega 2 (7), S. 3616-3631.

Lieb, Sebastian, Littmann, Timo, Plank, Nicole, Felixberger, Johannes, Tanaka, Miho, Schäfer, Thorsten, Krief, Stéphane, Elz, Sigurd, Friedland, Kristina, Bernhardt, Günther, Wegener, Joachim, Ozawa, Takeaki und Buschauer, Armin (2016) Label-free versus conventional cellular assays: functional investigations on the human histamine H1 receptor. Pharmacological Research 114, S. 13-26. Volltext nicht vorhanden.

Reinartz, Michael T., Kälble, Solveig, Littmann, Timo, Ozawa, Takeaki, Dove, Stefan, Kaever, Volkhard, Wainer, Irving W. und Seifert, Roland (2015) Structure-bias relationships for fenoterol stereoisomers in six molecular and cellular assays at the β2-adrenoceptor. Naunyn-Schmiedeberg's archives of pharmacology 388 (1), S. 51-65. Volltext nicht vorhanden.

Littmann, Timo, Ozawa, Takeaki und Bernhardt, Günther (2021) 7. Quantitative Determination and Imaging of Gαq Signaling in Live Cells via Split-Luciferase Complementation. In: Kim, Dung-Bae, (ed.) Live Cell Imaging: Methods and Protocols. Methods in Molecular Biology, 2274 (7). Humana, Springer Science+Business Media, LLC, part of Springer Nature 2021, New York, S. 69-78. ISBN 978-1-0716-1257-6. Volltext nicht vorhanden.

Littmann, Timo (2020) Towards a method for the simultaneous quantification of Gαq activation β-arrestin2 recruitment. Dissertation, Universität Regensburg.