Anzahl der Einträge: 23.
2022
Cigliano, Antonio,
Zhang, Shanshan,
Ribback, Silvia,
Steinmann, Sara,
Sini, Marcella,
Ament, Cindy E.,
Utpatel, Kirsten,
Song, Xinhua,
Wang, Jingxiao ,
Pilo, Maria G.,
Berger, Fabian,
Wang, Haichuan ,
Tao, Junyan,
Li, Xiaolei,
Pes, Giovanni M. ,
Mancarella, Serena,
Giannelli, Gianluigi,
Dombrowski, Frank,
Evert, Matthias,
Calvisi, Diego F.,
Chen, Xin und
Evert, Katja
(2022)
The Hippo pathway effector TAZ induces intrahepatic cholangiocarcinoma in mice and is ubiquitously activated in the human disease.
Journal of Experimental & Clinical Cancer Research 41, art.no.192.
Wang, Haichuan,
Zhang, Shanshan,
Zhang, Yi,
Jia, Jiaoyuan,
Wang, Jingxiao,
Liu, Xianqiong,
Zhang, Jie,
Song, Xinhua,
Ribback, Silvia,
Cigliano, Antonio,
Evert, Matthias,
Liang, Bingyong,
Wu, Hong,
Calvisi, Diego F.,
Zeng, Yong und
Chen, Xin
(2022)
TAZ is indispensable for c-MYC-induced hepatocarcinogenesis.
Journal of Hepatology 76 (1), S. 123-134.
Volltext nicht vorhanden.
Zhang, Yi,
Xu, Hongwei,
Cui, Guofei,
Liang, Binyong,
Chen, Xiangzheng,
Ko, Sungjin,
Affo, Silvia,
Song, Xinhua,
Liao, Yi,
Feng, Jianguo,
Wang, Pan ,
Wang, Haichuan ,
Xu, Meng,
Wang, Jingxiao ,
Pes, Giovanni M. ,
Ribback, Silvia,
Zeng, Yong,
Singhi, Aatur,
Schwabe, Robert F.,
Monga, Satdarshan P.,
Evert, Matthias,
Tang, Liling,
Calvisi, Diego F. und
Chen, Xin
(2022)
β-Catenin Sustains and Is Required for YES-associated Protein Oncogenic Activity in Cholangiocarcinoma.
Gastroenterology 163 (2), S. 481-494.
Volltext nicht vorhanden.
2021
Xu, Hongwei,
Chen, Kefei,
Shang, Runze,
Chen, Xinyan,
Zhang, Yi,
Song, Xinhua,
Evert, Matthias,
Zhong, Sheng,
Li, Bo,
Calvisi, Diego F. und
Chen, Xin
(2021)
Alpelisib combination treatment as novel targeted therapy against hepatocellular carcinoma.
Cell Death & Disease 12 (10).
Volltext nicht vorhanden.
Wang, Haichuan ,
Wang, Jingxiao ,
Zhang, Shanshan,
Jia, Jiaoyuan,
Liu, Xianqiong,
Zhang, Jie,
Wang, Pan ,
Song, Xinhua,
Che, Li,
Liu, Ke,
Ribback, Silvia,
Cigliano, Antonio ,
Evert, Matthias,
Wu, Hong,
Calvisi, Diego F.,
Zeng, Yong und
Chen, Xin
(2021)
Distinct and Overlapping Roles of Hippo Effectors YAP and TAZ During Human and Mouse Hepatocarcinogenesis.
Cellular and Molecular Gastroenterology and Hepatology 11 (4), S. 1095-1117.
Volltext nicht vorhanden.
Wang, Haichuan ,
Wang, Pan ,
Xu, Meng,
Song, Xinhua,
Wu, Hong,
Evert, Matthias,
Calvisi, Diego F.,
Zeng, Yong und
Chen, Xin
(2021)
Distinct functions of transforming growth factor-β signaling in c-MYC driven hepatocellular carcinoma initiation and progression.
Cell Death & Disease 12 (2).
Volltext nicht vorhanden.
Song, Xinhua,
Xu, Hongwei,
Wang, Pan ,
Wang, Jingxiao ,
Affo, Silvia ,
Wang, Haichuan ,
Xu, Meng,
Liang, Binyong,
Che, Li,
Qiu, Wei ,
Schwabe, Robert F.,
Chang, Tammy T.,
Vogl, Marion,
Pes, Giovanni M. ,
Ribback, Silvia,
Evert, Matthias,
Chen, Xin und
Calvisi, Diego F.
(2021)
Focal adhesion kinase (FAK) promotes cholangiocarcinoma development and progression via YAP activation.
Journal of Hepatology 75 (4), S. 888-899.
Volltext nicht vorhanden.
Zhang, Yi,
Liang, Binyong,
Song, Xinhua,
Wang, Haichuan ,
Evert, Matthias,
Zhou, Yi,
Calvisi, Diego F.,
Tang, Liling und
Chen, Xin
(2021)
Loss of Apc Cooperates with Activated Oncogenes to Induce Liver Tumor Formation in Mice.
The American Journal of Pathology 191 (5), S. 930-946.
Volltext nicht vorhanden.
Wang, Haichuan ,
Song, Xinhua,
Liao, Haotian,
Wang, Pan ,
Zhang, Yi,
Che, Li,
Zhang, Jie,
Zhou, Yi,
Cigliano, Antonio,
Ament, Cindy,
Superville, Daphne,
Ribback, Silvia,
Reeves, Melissa,
Pes, Giovanni M. ,
Liang, Binyong,
Wu, Hong,
Evert, Matthias,
Calvisi, Diego F.,
Zeng, Yong und
Chen, Xin
(2021)
Overexpression of Mothers Against Decapentaplegic Homolog 7 Activates the Yes‐Associated Protein/NOTCH Cascade and Promotes Liver Carcinogenesis in Mice and Humans.
Hepatology 74 (1), S. 248-263.
Volltext nicht vorhanden.
Affo, Silvia ,
Nair, Ajay ,
Brundu, Francesco ,
Ravichandra, Aashreya ,
Bhattacharjee, Sonakshi,
Matsuda, Michitaka,
Chin, LiKang,
Filliol, Aveline ,
Wen, Wen ,
Song, Xinhua,
Decker, Aubrianna,
Worley, Jeremy,
Caviglia, Jorge Matias,
Yu, Lexing,
Yin, Deqi,
Saito, Yoshinobu ,
Savage, Thomas,
Wells, Rebecca G.,
Mack, Matthias,
Zender, Lars,
Arpaia, Nicholas,
Remotti, Helen E.,
Rabadan, Raul,
Sims, Peter,
Leblond, Anne-Laure,
Weber, Achim,
Riener, Marc-Oliver,
Stockwell, Brent R.,
Gaublomme, Jellert,
Llovet, Josep M. ,
Kalluri, Raghu ,
Michalopoulos, George K.,
Seki, Ekihiro ,
Sia, Daniela ,
Chen, Xin,
Califano, Andrea und
Schwabe, Robert F.
(2021)
Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations.
Cancer Cell 39 (6), 866-882.e11.
Volltext nicht vorhanden.
Liang, Binyong,
Zhou, Yi,
Qian, Manning,
Xu, Meng,
Wang, Jingxiao ,
Zhang, Yi,
Song, Xinhua,
Wang, Haichuan ,
Lin, Shumei,
Ren, Chuanli,
Monga, Satdarshan P.,
Wang, Bruce ,
Evert, Matthias,
Chen, Yifa,
Chen, Xiaoping,
Huang, Zhiyong,
Calvisi, Diego F. und
Chen, Xin
(2021)
TBX3 functions as a tumor suppressor downstream of activated CTNNB1 mutants during hepatocarcinogenesis.
Journal of Hepatology 75 (1), S. 120-131.
Volltext nicht vorhanden.
2020
Shang, Runze,
Song, Xinhua,
Wang, Pan,
Zhou, Yi,
Lu, Xinjun,
Wang, Jingxiao,
Xu, Meng,
Chen, Xinyan,
Utpatel, Kirsten,
Che, Li,
Liang, Binyong,
Cigliano, Antonio,
Evert, Matthias,
Calvisi, Diego F. und
Chen, Xin
(2020)
Cabozantinib-based combination therapy for the treatment of hepatocellular carcinoma.
Gut 70 (9), S. 1746-1757.
Volltext nicht vorhanden.
Zhou, Yi,
Xu, Meng,
Liu, Pin,
Liang, Binyong,
Qian, Manning,
Wang, Haichuan ,
Song, Xinhua,
Nyshadham, Pranavanand,
Che, Li,
Calvisi, Diego F.,
Li, Feng,
Lin, Shumei und
Chen, Xin
(2020)
Mammalian Target of Rapamycin Complex 2 Signaling Is Required for Liver Regeneration in a Cholestatic Liver Injury Murine Model.
The American Journal of Pathology 190 (7), S. 1414-1426.
Volltext nicht vorhanden.
Wang, Pan ,
Song, Xinhua,
Cao, Dan,
Cui, Kairong,
Wang, Jingxiao ,
Utpatel, Kirsten,
Shang, Runze ,
Wang, Haichuan ,
Che, Li,
Evert, Matthias,
Zhao, Keji,
Calvisi, Diego F. und
Chen, Xin
(2020)
Oncogene-dependent function of BRG1 in hepatocarcinogenesis.
Cell Death & Disease 11 (2).
Volltext nicht vorhanden.
Xu, Meng,
Wang, Haichuan ,
Wang, Jingxiao ,
Burhan, Deviana ,
Shang, Runze ,
Wang, Pan ,
Zhou, Yi,
Li, Rong,
Liang, Bingyong,
Evert, Katja,
Utpatel, Kirsten,
Xu, Zhong,
Song, Xinhua,
Che, Li,
Calvisi, Diego F.,
Wang, Bruce ,
Chen, Xi,
Zeng, Yong und
Chen, Xin
(2020)
mTORC2 Signaling Is Necessary for Timely Liver Regeneration after Partial Hepatectomy.
The American Journal of Pathology 190 (4), S. 817-829.
Volltext nicht vorhanden.
2019
Qiao, Yu,
Wang, Jingxiao,
Karagoz, Eylul,
Liang, Binyong,
Song, Xinhua,
Shang, Runze,
Evert, Katja,
Xu, Meng,
Che, Li,
Evert, Matthias,
Calvisi, Diego F.,
Tao, Junyan,
Wang, Bruce,
Monga, Satdarshan P. und
Chen, Xin
(2019)
Axis inhibition protein 1 (Axin1) Deletion–Induced Hepatocarcinogenesis Requires Intact β‐Catenin but Not Notch Cascade in Mice.
Hepatology 70 (6), S. 2003-2017.
Volltext nicht vorhanden.
Che, Li,
Chi, Wenna,
Qiao, Yu,
Zhang, Jie,
Song, Xinhua,
Liu, Ye,
Li, Lei,
Jia, Jiaoyuan,
Pilo, Maria G.,
Wang, Jingxiao,
Cigliano, Antonio ,
Ma, Zhilong,
Kuang, Wenhua,
Tang, Zefang,
Zhang, Zemin,
Shui, Guanghou,
Ribback, Silvia,
Dombrowski, Frank,
Evert, Matthias,
Pascale, Rosa Maria,
Cossu, Carla,
Pes, Giovanni Mario ,
Osborne, Timothy F.,
Calvisi, Diego F.,
Chen, Xin und
Chen, Ligong
(2019)
Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans.
Gut 69 (1), S. 177-186.
Volltext nicht vorhanden.
Liu, Xianqiong,
Hu, Junjie,
Song, Xinhua,
Utpatel, Kirsten,
Evert, Matthias und
Calvisi, Diego F.
(2019)
Combined treatment with MEK and mTOR inhibitors is effective in vitro and in vivo models of hepatocellular carcinoma.
Cancers 11, S. 930.
Wang, Jingxiao ,
Wang, Haichuan ,
Peters, Michele,
Ding, Ning,
Ribback, Silvia,
Utpatel, Kirsten,
Cigliano, Antonio,
Dombrowski, Frank,
Xu, Meng,
Chen, Xinyan,
Song, Xinhua,
Che, Li,
Evert, Matthias,
Cossu, Antonio,
Gordan, John,
Zeng, Yong,
Chen, Xin und
Calvisi, Diego F.
(2019)
Loss of Fbxw7 synergizes with activated Akt signaling to promote c-Myc dependent cholangiocarcinogenesis.
Journal of Hepatology 71 (4), S. 742-752.
Volltext nicht vorhanden.
Wang, Pan,
Song, Xinhua,
Utpatel, Kirsten,
Shang, Runze,
Yang, Yoon Mee,
Xu, Meng,
Zhang, Jie,
Che, Li,
Gordan, John,
Cigliano, Antonio,
Seki, Ekihiro ,
Evert, Matthias,
Calvisi, Diego F.,
Hu, Xiaosong und
Chen, Xin
(2019)
MEK inhibition suppresses K-Ras wild-type cholangiocarcinoma in vitro and in vivo via inhibiting cell proliferation and modulating tumor microenvironment.
Cell Death & Disease 10 (2).
Volltext nicht vorhanden.
Xu, Meng,
Wang, Jingxiao,
Xu, Zhong,
Li, Rong,
Wang, Pan,
Shang, Runze,
Cigliano, Antonio,
Ribback, Silvia,
Solinas, Antonio ,
Pes, Giovanni Mario ,
Evert, Katja,
Wang, Haichuan,
Song, Xinhua,
Zhang, Shu,
Che, Li,
Pascale, Rosa Maria,
Calvisi, Diego F.,
Liu, Qingguang und
Chen, Xin
(2019)
SNAI1 promotes the cholangiocellular phenotype, but not epithelial-mesenchymal transition, in a murine hepatocellular carcinoma model.
Cancer Research 79 (21), S. 5563-5574.
Volltext nicht vorhanden.
2018
Song, Xinhua,
Liu, Xianqiong,
Wang, Haichuan ,
Wang, Jingxiao ,
Qiao, Yu,
Cigliano, Antonio,
Utpatel, Kirsten,
Ribback, Silvia,
Pilo, Maria G.,
Serra, Marina,
Gordan, John D.,
Che, Li,
Zhang, Shanshan,
Cossu, Antonio,
Porcu, Alberto,
Pascale, Rosa M.,
Dombrowski, Frank,
Hu, Hongbo,
Calvisi, Diego F.,
Evert, Matthias und
Chen, Xin
(2018)
Combined CDK4/6 and Pan-mTOR Inhibition Is Synergistic Against Intrahepatic Cholangiocarcinoma.
Clinical Cancer Research 25 (1), S. 403-413.
Volltext nicht vorhanden.
2017
Zhang, Shanshan,
Song, Xinhua,
Cao, Dan,
Xu, Zhong,
Fan, Biao,
Che, Li,
Hu, Junjie,
Chen, Bin,
Dong, Mingjie,
Pilo, Maria G.,
Cigliano, Antonio ,
Evert, Katja,
Ribback, Silvia,
Dombrowski, Frank,
Pascale, Rosa M.,
Cossu, Antonio,
Vidili, Gianpaolo,
Porcu, Alberto,
Simile, Maria M.,
Pes, Giovanni M.,
Giannelli, Gianluigi,
Gordan, John,
Wei, Lixin,
Evert, Matthias,
Cong, Wenming,
Calvisi, Diego F. und
Chen, Xin
(2017)
Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice.
Journal of Hepatology 67 (6), S. 1194-1203.
Volltext nicht vorhanden.
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