Einträge von Thasler, Wolfgang E. auf dem Publikationsserver

Seitz, Tatjana, John, Nora, Sommer, Judith , Dietrich, Peter, Thasler, Wolfgang E., Hartmann, Arndt, Evert, Katja, Lang, Sven A., Bosserhoff, Anja und Hellerbrand, Claus (2022) Role of Fibroblast Growth Factors in the Crosstalk of Hepatic Stellate Cells and Uveal Melanoma Cells in the Liver Metastatic Niche. International Journal of Molecular Sciences 23 (19), S. 11524.

Gaza, Anne, Fritz, Valerie, Malek, Lara, Wormser, Laura, Treiber, Nora, Danner, Johannes, Kremer, Andreas E., Thasler, Wolfgang E., Siebler, Jürgen, Meister, Gunter, Neurath, Markus F., Hellerbrand, Claus, Bosserhoff, Anja K. und Dietrich, Peter (2021) Identification of novel targets of miR-622 in hepatocellular carcinoma reveals common regulation of cooperating genes and outlines the oncogenic role of zinc finger CCHC-type containing 11. Neoplasia 23 (5), S. 502-514. Volltext nicht vorhanden.

Sommer, Judith, Dorn, Christoph , Gäbele, Erwin, Bataille, Frauke, Freese, Kim, Seitz, Tatjana, Thasler, Wolfgang E., Büttner, Reinhard, Weiskirchen, Ralf , Bosserhoff, Anja und Hellerbrand, Claus (2020) Four-And-A-Half LIM-Domain Protein 2 (FHL2) Deficiency Aggravates Cholestatic Liver Injury. Cells 9 (1), S. 248.

Klag, Thomas, Thomas, Maria, Ehmann, Dirk, Courth, Lioba, Mailänder-Sanchez, Daniela, Weiss, Thomas S. , Dayoub, Rania , Abshagen, Kerstin, Vollmar, Brigitte, Thasler, Wolfgang E., Stange, Eduard F., Berg, Christoph P., Malek, Nisar P., Zanger, Ulrich M. und Wehkamp, Jan (2018) β-Defensin 1 Is Prominent in the Liver and Induced During Cholestasis by Bilirubin and Bile Acids via Farnesoid X Receptor and Constitutive Androstane Receptor. Frontiers in Immunology 9. Volltext nicht vorhanden.

Sommer, Judith, Mahli, Abdo , Freese, Kim, Schiergens, Tobias S., Kuecuekoktay, Fulya Suzan, Teufel, Andreas, Thasler, Wolfgang E., Müller, Martina, Bosserhoff, Anja K. und Hellerbrand, Claus (2017) Analysis of molecular mechanisms of 5-fluorouracil-induced steatosis and inflammation <i>in vitro</i> and in mice. Oncotarget 8 (8). Volltext nicht vorhanden.

Jeske, Judith, Bitter, Andreas, Thasler, Wolfgang E., Weiss, Thomas S. , Schwab, Matthias und Burk, Oliver (2017) Ligand-dependent and -independent regulation of human hepatic sphingomyelin phosphodiesterase acid-like 3A expression by pregnane X receptor and crosstalk with liver X receptor. Biochemical Pharmacology 136, S. 122-135. Volltext nicht vorhanden.

Diener, Markus K., Hüttner, Felix J., Kieser, Meinhard, Knebel, Phillip, Dörr-Harim, Colette, Distler, Marius, Grützmann, Robert, Wittel, Uwe A., Schirren, Rebekka, Hau, Hans-Michael, Kleespies, Axel, Heidecke, Claus-Dieter, Tomazic, Ales, Halloran, Christopher M., Wilhelm, Torsten J., Bahra, Marcus, Beckurts, Tobias, Börner, Thomas, Glanemann, Matthias, Steger, Ulrich, Treitschke, Frank, Staib, Ludger, Thelen, Karsten, Bruckner, Thomas, Mihaljevic, André L., Werner, Jens, Ulrich, Alexis, Hackert, Thilo, Büchler, Markus W., Rossion, Inga, Kunz, Alexandra, Hund, Evelin, Limprecht, Ronald, Schlitt, Hans Jürgen, Mössner, Joachim, Seiler, Christoph M., Ihorst, Gabriele, Di Sebastiano, Pierluigi, Witzigmann, Helmut, Klein, Fritz, Berthold, Heike, Körnlein, Heike, Hopt, Ulrich, Sick, Olivia, Keck, Tobias, Partecke, Lars Ivo, Peters, Sebastian, Lerch, Markus M., Maichle, Barbara, Erni, Birgit, Bunjes-Schmieger, Sabine, Igel, Sarah, Stemmle, Svenja, Neoptolemos, John P., Raraty, Michael G. T., Petric, Miha, Niedergethmann, Marco, Schwarzmeier, Claudia, Renz, Bernhard, Schreib, Brigitte, Thasler, Wolfgang E., Schoenberg, Michael H., Friess, Helmut, Reim, Daniel, Ceyhan, Güralp O., Diehl-Bein, Monika, Simon, Thomas, Gehrig, Tobias, Hoffer, Marion und Germer, Christoph Thomas (2017) Partial pancreatoduodenectomy versus duodenum-preserving pancreatic head resection in chronic pancreatitis: the multicentre, randomised, controlled, double-blind ChroPac trial. The Lancet 390 (10099), S. 1027-1037. Volltext nicht vorhanden.

Godoy, Patricio, Widera, Agata, Schmidt-Heck, Wolfgang, Campos, Gisela, Meyer, Christoph, Cadenas, Cristina, Reif, Raymond, Stöber, Regina, Hammad, Seddik, Pütter, Larissa, Gianmoena, Kathrin, Marchan, Rosemarie , Ghallab, Ahmed , Edlund, Karolina, Nüssler, Andreas, Thasler, Wolfgang E., Damm, Georg, Seehofer, Daniel, Weiss, Thomas S. , Dirsch, Olaf, Dahmen, Uta, Gebhardt, Rolf, Chaudhari, Umesh, Meganathan, Kesavan, Sachinidis, Agapios, Kelm, Jens, Hofmann, Ute , Zahedi, René P. , Guthke, Reinhard, Blüthgen, Nils, Dooley, Steven und Hengstler, Jan G. (2016) Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue. Archives of Toxicology 90 (10), S. 2513-2529. Volltext nicht vorhanden.

Engelmann, Julia C. , Amann, Thomas, Ott-Rötzer, Brigitta, Nützel, Margit, Reinders, Yvonne, Reinders, Jörg, Thasler, Wolfgang E., Kristl, Theresa, Teufel, Andreas, Huber, Christian G. , Oefner, Peter J. , Spang, Rainer und Hellerbrand, Claus (2015) Causal Modeling of Cancer-Stromal Communication Identifies PAPPA as a Novel Stroma-Secreted Factor Activating NFκB Signaling in Hepatocellular Carcinoma. PLoS Computational Biology 11 (5), S. 1-22.

Weiß, Frederik, Schnabel, Anke, Planatscher, Hannes, van den Berg, Bart H. J., Serschnitzki, Bettina, Nuessler, Andreas K., Thasler, Wolfgang E., Weiss, Thomas S. , Reuss, Matthias, Stoll, Dieter, Templin, Markus F., Joos, Thomas O., Marcus, Katrin und Poetz, Oliver (2015) Indirect protein quantification of drug-transforming enzymes using peptide group-specific immunoaffinity enrichment and mass spectrometry. Scientific Reports 5.

Mahli, Abdo , Thasler, Wolfgang E., Patsenker, Eleonora, Müller, Sebastian, Stickel, Felix, Müller, Martina, Seitz, Helmut K., Cederbaum, Arthur I. und Hellerbrand, Claus (2015) Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro. Oncotarget 6 (39), S. 41464-41478. Volltext nicht vorhanden.

Grinberg, Marianna, Stöber, Regina M., Edlund, Karolina, Rempel, Eugen, Godoy, Patricio, Reif, Raymond, Widera, Agata, Madjar, Katrin , Schmidt-Heck, Wolfgang, Marchan, Rosemarie , Sachinidis, Agapios, Spitkovsky, Dimitry, Hescheler, Jürgen, Carmo, Helena , Arbo, Marcelo D. , van de Water, Bob, Wink, Steven, Vinken, Mathieu , Rogiers, Vera, Escher, Sylvia, Hardy, Barry, Mitic, Dragana, Myatt, Glenn, Waldmann, Tanja, Mardinoglu, Adil, Damm, Georg , Seehofer, Daniel, Nüssler, Andreas, Weiss, Thomas S. , Oberemm, Axel , Lampen, Alfons, Schaap, Mirjam M., Luijten, Mirjam, van Steeg, Harry, Thasler, Wolfgang E., Kleinjans, Jos C. S., Stierum, Rob H., Leist, Marcel , Rahnenführer, Jörg und Hengstler, Jan G. (2014) Toxicogenomics directory of chemically exposed human hepatocytes. Archives of Toxicology 88, S. 2261-2287. Volltext nicht vorhanden.

Godoy, Patricio, Hewitt, Nicola J., Albrecht, Ute, Andersen, Melvin E., Ansari, Nariman, Bhattacharya, Sudin, Bode, Johannes Georg, Bolleyn, Jennifer, Borner, Christoph, Böttger, Jan, Braeuning, Albert, Budinsky, Robert A., Burkhardt, Britta, Cameron, Neil R., Camussi, Giovanni, Cho, Chong-Su, Choi, Yun-Jaie, Craig Rowlands, J., Dahmen, Uta, Damm, Georg, Dirsch, Olaf, Donato, María Teresa, Dong, Jian, Dooley, Steven, Drasdo, Dirk, Eakins, Rowena, Ferreira, Karine Sá, Fonsato, Valentina, Fraczek, Joanna, Gebhardt, Rolf, Gibson, Andrew, Glanemann, Matthias, Goldring, Chris E. P., Gómez-Lechón, María José, Groothuis, Geny M. M., Gustavsson, Lena, Guyot, Christelle, Hallifax, David, Hammad, Seddik, Hayward, Adam, Häussinger, Dieter, Hellerbrand, Claus, Hewitt, Philip, Hoehme, Stefan, Holzhütter, Hermann-Georg, Houston, J. Brian, Hrach, Jens, Ito, Kiyomi, Jaeschke, Hartmut, Keitel, Verena, Kelm, Jens M., Kevin Park, B., Kordes, Claus, Kullak-Ublick, Gerd A., LeCluyse, Edward L., Lu, Peng, Luebke-Wheeler, Jennifer, Lutz, Anna, Maltman, Daniel J., Matz-Soja, Madlen, McMullen, Patrick, Merfort, Irmgard, Messner, Simon, Meyer, Christoph, Mwinyi, Jessica, Naisbitt, Dean J., Nussler, Andreas K., Olinga, Peter, Pampaloni, Francesco, Pi, Jingbo, Pluta, Linda, Przyborski, Stefan A., Ramachandran, Anup, Rogiers, Vera, Rowe, Cliff, Schelcher, Celine, Schmich, Kathrin, Schwarz, Michael, Singh, Bijay, Stelzer, Ernst H. K., Stieger, Bruno, Stöber, Regina, Sugiyama, Yuichi, Tetta, Ciro, Thasler, Wolfgang E., Vanhaecke, Tamara, Vinken, Mathieu, Weiss, Thomas S. , Widera, Agata, Woods, Courtney G., Xu, Jinghai James, Yarborough, Kathy M. und Hengstler, Jan G. (2013) Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. Archives of Toxicology 87, S. 1315-1530.

Czech, Barbara, Dettmer, Katja , Valletta, Daniela, Saugspier, Michael Sebastian, Koch, Andreas, Stevens, Axel Peter, Thasler, Wolfgang E., Müller, Martina, Oefner, Peter J. , Bosserhoff, Anja-Katrin und Hellerbrand, Claus (2013) Expression and function of methylthioadenosine phosphorylase in chronic liver disease. PloS ONE 8 (12), e80703.

Valletta, Daniela, Czech, Barbara, Thasler, Wolfgang E., Müller, Martina, Bosserhoff, Anja-Katrin und Hellerbrand, Claus (2012) Expression and function of the atypical cadherin FAT1 in chronic liver disease. Biochemical and Biophysical Research Communications 426 (3), S. 404-408. Volltext nicht vorhanden.

Saugspier, Michael, Dorn, Christoph , Thasler, Wolfgang E., Gehrig, Manfred, Heilmann, Jörg und Hellerbrand, Claus (2012) Hop bitter acids exhibit anti-fibrogenic effects on hepatic stellate cells in vitro. Experimental and Molecular Pathology 92 (2), S. 222-228. Volltext nicht vorhanden.

Nussler, Andreas K., Zeilinger, Katrin, Schyschka, Lilianna, Ehnert, Sabrina, Gerlach, Jörg C., Yan, Xueying, Lee, Serene M. L. , Ilowski, Maren, Thasler, Wolfgang E. und Weiss, Thomas S. (2011) Cell therapeutic options in liver diseases: cell types, medical devices and regulatory issues. Journal of Materials Science: Materials in Medicine 22 (5), S. 1087-1099. Volltext nicht vorhanden.

Bucher, Joachim, Riedmaier, Stephan, Schnabel, Anke, Marcus, Katrin, Vacun, Gabriele, Weiss, Thomas S. , Thasler, Wolfgang E., Nüssler, Andreas K., Zanger, Ulrich M. und Reuss, Matthias (2011) A systems biology approach to dynamic modeling and inter-subject variability of statin pharmacokinetics in human hepatocytes. BMC systems biology 5 (1), S. 66.

Feidt, Diana M., Klein, Kathrin, Hofmann, Ute , Riedmaier, Stephan, Knobeloch, Daniel, Thasler, Wolfgang E., Weiss, Thomas S. , Schwab, Matthias und Zanger, Ulrich M. (2010) Profiling Induction of Cytochrome P450 Enzyme Activity by Statins Using a New Liquid Chromatography-Tandem Mass Spectrometry Cocktail Assay in Human Hepatocytes. Drug Metabolism and Disposition 38 (9), S. 1589-1597. Volltext nicht vorhanden.

Hoffart, Ella, Nuessler, Andreas K., Thasler, Wolfgang E., Weiss, Thomas S. , Schwab, Matthias und Burk, Oliver (2009) Molecular mechanism of cytochrome P450 induction by atorvastatin and atorvastatin metabolites. In: 16th North American Regional ISSX Meeting, OCT 18-22, 2009, Baltimore, MD. Volltext nicht vorhanden.

Jeschke, Marc G., Klein, Dagmar, Thasler, Wolfgang E., Bolder, Ulrich, Schlitt, Hans-Jürgen, Jauch, Karl-Walter und Weiss, Thomas S. (2008) Insulin Decreases Inflammatory Signal Transcription Factor Expression in Primary Human Liver Cells after LPS Challenge. Molecular Medicine 14, S. 11-19.

Brand, Stephan, Dambacher, Julia, Beigel, Florian, Zitzmann, Kathrin, Heeg, Malte H. J., Weiss, Thomas S. , Prüfer, Thomas, Olszak, Torsten, Steib, Christian J., Storr, Martin, Göke, Burkhard, Diepolder, Helmut, Bilzer, Manfred, Thasler, Wolfgang E. und Auernhammer, Christoph J. (2007) IL-22-mediated liver cell regeneration is abrogated by SOCS-1/3 overexpression in vitro. American Journal of Physiology-Gastrointestinal and Liver Physiology 292 (4), G1019-G1028.

Thasler, Wolfgang E., Schlott, Thilo, Kalkuhl, Arno, Plän, Thomas, Irrgang, Bernhard, Jauch, Karl-Walter und Weiss, Thomas S. (2006) Human Tissue for In Vitro Research as an Alternative to Animal Experiments: A Charitable “Honest Broker” Model to Fulfil Ethical and Legal Regulations and to Protect Research Participants. Alternatives to Laboratory Animals 34 (4), S. 387-392. Volltext nicht vorhanden.

Dayoub, Rania , Thasler, Wolfgang E., Bosserhoff, Anja K. , Singer, Thomas, Jauch, Karl-Walter, Schlitt, Hans J. und Weiss, Thomas S. (2006) Regulation of polyamine synthesis in human hepatocytes by hepatotrophic factor augmenter of liver regeneration. Biochemical and biophysical research communications 345 (1), S. 181-187. Zugang zum Volltext eingeschränkt.

Thasler, Wolfgang E., Dayoub, Rania , Mühlbauer, Marcus, Hellerbrand, Claus, Singer, Thomas, Gräbe, Anja, Jauch, Karl-Walter, Schlitt, Hans-Jürgen und Weiss, Thomas S. (2006) Repression of cytochrome P450 activity in human hepatocytes in vitro by a novel hepatotrophic factor, augmenter of liver regeneration. The Journal of pharmacology and experimental therapeutics 316 (2), S. 822-829. Zugang zum Volltext eingeschränkt.

Thasler, Wolfgang E., Weiss, Thomas S. , Letschert, K., Tausch, U., Jilg, Wolfgang, Hellerbrand, Claus und Jauch, K. W. (2006) The human liver in vitro model: Potential of primary human hepatocytes for experimental and clinical research. Langenbeck's Archives of Surgery 386 (6), S. 475-476. Volltext nicht vorhanden.

Mühlbauer, Marcus, Bosserhoff, Anja K., Hartmann, Arndt, Thasler, Wolfgang E., Weiss, Thomas S. , Herfarth, Hans, Lock, Guntram, Schölmerich, Jürgen und Hellerbrand, Claus (2005) A novel MCP-1 gene polymorphism is associated with hepatic MCP-1 expression and severity of HCV-related liver disease. Gastroenterology 125 (4), S. 1085-1093.

Boehm, Stephan, Thasler, Wolfgang E., Weiss, Thomas S. und Jilg, Wolfgang (2005) Primary Human Hepatocytes as an in vitro Model for Hepatitis B Virus Infection. Monographs in Virology / Models of Viral Hepatitis 25, S. 119-134. Volltext nicht vorhanden.

Mühlbauer, Marcus, Weiss, Thomas S. , Thasler, Wolfgang E., Gelbmann, Cornelia M., Schnabl, Bernd, Schölmerich, Jürgen und Hellerbrand, Claus (2004) LPS-mediated NFκB activation varies between activated human hepatic stellate cells from different donors. Biochemical and Biophysical Research Communications 325 (1), S. 191-197. Volltext nicht vorhanden.

Mühlbauer, Marcus, Weiss, Thomas S. , Thasler, Wolfgang E., Gelbmann, Cornelia M., Schnabl, Bernd, Schölmerich, Jürgen und Hellerbrand, Claus (2004) LPS-mediated NFκB activation varies between activated human hepatic stellate cells from different donors. Biochemical and Biophysical Research Communications 325 (1), S. 191-197. Volltext nicht vorhanden.

Thasler, Wolfgang E., Weiss, Thomas S. , Schillhorn, Kerrin, Stoll, Peter-Tobias, Irrgang, Bernhard und Jauch, Karl-Walter (2003) Charitable State-Controlled Foundation Human Tissue and Cell Research: Ethic and Legal Aspects in the Supply of Surgically Removed Human Tissue For Research in the Academic and Commercial Sector in Germany. Cell and Tissue Banking 4, S. 49-56. Volltext nicht vorhanden.

Weiss, Thomas S. , Pahernik, Sascha, Scheruebl, Irmgard, Jauch, Karl-Walter und Thasler, Wolfgang E. (2003) Cellular damage to human hepatocytes through repeated application of 5-aminolevulinic acid. Journal of Hepatology 38 (4), S. 476-482. Volltext nicht vorhanden.

Mühlbauer, Marcus, Thasler, Wolfgang E., Weiss, Thomas S. , Schölmerich, Jürgen und Hellerbrand, Claus (2002) An in vitro model with kryoconserved human activated hepatic stellate cells: Reflecting heterogeneity of profibrotic and proinflammatory gene expression. In: 53rd Annual Meeting of the Association-for-the-Study-of-Liver-Diseases (AASLD), NOV 01-05, 2002, BOSTON, MASSACHUSETTS. Volltext nicht vorhanden.

Orr, Samantha, Alexandre, Eliane, Clark, Brain, Combes, Robert, Fels, Lueder M., Gray, Neil, Jönsson-Rylander, Ann-Cathrine, Helin, Heikki, Koistinen, Jukka, Oinonen, Teija, Richert, Lysiane, Ravid, Rivka, Salonen, Jarmo, Teesalu, Tambet, Thasler, Wolfgang E., Trafford, Jacki, van der Valk, Jan, von Versen, Rudiger, Weiss, Thomas S. , Womack, Chris und Ylikomi, Timo (2002) The establishment of a network of European human research tissue banks. Cell and Tissue Banking 3, S. 133-137. Volltext nicht vorhanden.

Weiss, Thomas S. , Bernhardt, Günther, Buschauer, Armin, Thasler, Wolfgang E., Dolgner, Doris, Zirngibl, Hubert und Jauch, Karl-Walter (2002) Polyamine levels of human colorectal adenocarcinomas are correlate with tumor stage and grade,. International Journal of Colorectal Disease 17 (6), S. 381-387. Volltext nicht vorhanden.

Kalkuhl, Arno, Thasler, Wolfgang E., Krebsfaenger, N., Weiss, Thomas S. , Bader, R., Jauch, K. W. und Singer, T. (2001) Use of primary rat and human hepatocytes in early peclinical drug safety evaluation. Naunyn - Schmiedebergs Archives of Pharmacology 363 (4), R163. Volltext nicht vorhanden.

Anderson, Robert, Balls, Michael, Burke, M. Danny, Cummins, Marie, Fehily, Deirdre, Gray, Neil, de Groot, Marleen G., Helin, Heikki, Hunt, Charles, Jones, David, Price, David A. , Richert, Lysiane, Ravid, Rivka, Shute, David, Śladowski, Dariusz, Stone, Helena, Thasler, Wolfgang E., Trafford, Jacki, van der Valk, Jan, Weiss, Thomas S. , Womack, Chris und Ylikomi, Timo (2001) The Establishment of Human Research Tissue Banking in the UK and Several Western European Countries. In: ECVAM Workshop 44, 8–10 September 2000, The Belfry, Birmingham, UK. Volltext nicht vorhanden.

Thasler, Wolfgang E., Weiss, Thomas S. , Abels, C., Hellerbrand, Claus , Bolder, U., Wagner, J., Szeimies, R. M. und Jauch, Karl-Walter (1999) Oxidative cell damage induced by repeated application of 5-aminolevulinic acid in human hepatocyte cultures. Hepatology 30 (4), 400A. Volltext nicht vorhanden.

Thasler, Wolfgang E., Letschert, K. C., Weiss, Thomas S. , Weinberger, K. M., Bolder, U. und Jauch, Karl-Walter (1999) Vaccinia mediated gene transfer into human hepatocytes - Efficiency and function under transplant conditions in vitro. Langenbecks Archives of Surgery (1), S. 247-251. Volltext nicht vorhanden.