Anzahl der Einträge: 21.
Artikel
Wang, Haichuan ,
Wang, Jingxiao ,
Zhang, Shanshan,
Jia, Jiaoyuan,
Liu, Xianqiong,
Zhang, Jie,
Wang, Pan ,
Song, Xinhua,
Che, Li,
Liu, Ke,
Ribback, Silvia,
Cigliano, Antonio ,
Evert, Matthias,
Wu, Hong,
Calvisi, Diego F.,
Zeng, Yong und
Chen, Xin
(2021)
Distinct and Overlapping Roles of Hippo Effectors YAP and TAZ During Human and Mouse Hepatocarcinogenesis.
Cellular and Molecular Gastroenterology and Hepatology 11 (4), S. 1095-1117.
Volltext nicht vorhanden.
Song, Xinhua,
Xu, Hongwei,
Wang, Pan ,
Wang, Jingxiao ,
Affo, Silvia ,
Wang, Haichuan ,
Xu, Meng,
Liang, Binyong,
Che, Li,
Qiu, Wei ,
Schwabe, Robert F.,
Chang, Tammy T.,
Vogl, Marion,
Pes, Giovanni M. ,
Ribback, Silvia,
Evert, Matthias,
Chen, Xin und
Calvisi, Diego F.
(2021)
Focal adhesion kinase (FAK) promotes cholangiocarcinoma development and progression via YAP activation.
Journal of Hepatology 75 (4), S. 888-899.
Volltext nicht vorhanden.
Wang, Haichuan ,
Song, Xinhua,
Liao, Haotian,
Wang, Pan ,
Zhang, Yi,
Che, Li,
Zhang, Jie,
Zhou, Yi,
Cigliano, Antonio,
Ament, Cindy,
Superville, Daphne,
Ribback, Silvia,
Reeves, Melissa,
Pes, Giovanni M. ,
Liang, Binyong,
Wu, Hong,
Evert, Matthias,
Calvisi, Diego F.,
Zeng, Yong und
Chen, Xin
(2021)
Overexpression of Mothers Against Decapentaplegic Homolog 7 Activates the Yes‐Associated Protein/NOTCH Cascade and Promotes Liver Carcinogenesis in Mice and Humans.
Hepatology 74 (1), S. 248-263.
Volltext nicht vorhanden.
Shang, Runze,
Song, Xinhua,
Wang, Pan,
Zhou, Yi,
Lu, Xinjun,
Wang, Jingxiao,
Xu, Meng,
Chen, Xinyan,
Utpatel, Kirsten,
Che, Li,
Liang, Binyong,
Cigliano, Antonio,
Evert, Matthias,
Calvisi, Diego F. und
Chen, Xin
(2020)
Cabozantinib-based combination therapy for the treatment of hepatocellular carcinoma.
Gut 70 (9), S. 1746-1757.
Volltext nicht vorhanden.
Zhou, Yi,
Xu, Meng,
Liu, Pin,
Liang, Binyong,
Qian, Manning,
Wang, Haichuan ,
Song, Xinhua,
Nyshadham, Pranavanand,
Che, Li,
Calvisi, Diego F.,
Li, Feng,
Lin, Shumei und
Chen, Xin
(2020)
Mammalian Target of Rapamycin Complex 2 Signaling Is Required for Liver Regeneration in a Cholestatic Liver Injury Murine Model.
The American Journal of Pathology 190 (7), S. 1414-1426.
Volltext nicht vorhanden.
Wang, Pan ,
Song, Xinhua,
Cao, Dan,
Cui, Kairong,
Wang, Jingxiao ,
Utpatel, Kirsten,
Shang, Runze ,
Wang, Haichuan ,
Che, Li,
Evert, Matthias,
Zhao, Keji,
Calvisi, Diego F. und
Chen, Xin
(2020)
Oncogene-dependent function of BRG1 in hepatocarcinogenesis.
Cell Death & Disease 11 (2).
Volltext nicht vorhanden.
Jia, Jiaoyuan,
Che, Li,
Cigliano, Antonio ,
Wang, Xue,
Peitta, Graziella,
Tao, Junyan,
Zhong, Sheng,
Ribback, Silvia,
Evert, Matthias,
Chen, Xin und
Calvisi, Diego F.
(2020)
Pivotal Role of Fatty Acid Synthase in c-MYC Driven Hepatocarcinogenesis.
International Journal of Molecular Sciences 21 (22), S. 8467.
Volltext nicht vorhanden.
Xu, Meng,
Wang, Haichuan ,
Wang, Jingxiao ,
Burhan, Deviana ,
Shang, Runze ,
Wang, Pan ,
Zhou, Yi,
Li, Rong,
Liang, Bingyong,
Evert, Katja,
Utpatel, Kirsten,
Xu, Zhong,
Song, Xinhua,
Che, Li,
Calvisi, Diego F.,
Wang, Bruce ,
Chen, Xi,
Zeng, Yong und
Chen, Xin
(2020)
mTORC2 Signaling Is Necessary for Timely Liver Regeneration after Partial Hepatectomy.
The American Journal of Pathology 190 (4), S. 817-829.
Volltext nicht vorhanden.
Che, Li,
Paliogiannis, Panagiotis,
Cigliano, Antonio ,
Pilo, Maria G.,
Chen, Xin und
Calvisi, Diego F.
(2019)
Pathogenetic, Prognostic, and Therapeutic Role of Fatty Acid Synthase in Human Hepatocellular Carcinoma.
Frontiers in Oncology 9 (1412), S. 1-10.
Qiao, Yu,
Wang, Jingxiao,
Karagoz, Eylul,
Liang, Binyong,
Song, Xinhua,
Shang, Runze,
Evert, Katja,
Xu, Meng,
Che, Li,
Evert, Matthias,
Calvisi, Diego F.,
Tao, Junyan,
Wang, Bruce,
Monga, Satdarshan P. und
Chen, Xin
(2019)
Axis inhibition protein 1 (Axin1) Deletion–Induced Hepatocarcinogenesis Requires Intact β‐Catenin but Not Notch Cascade in Mice.
Hepatology 70 (6), S. 2003-2017.
Volltext nicht vorhanden.
Che, Li,
Chi, Wenna,
Qiao, Yu,
Zhang, Jie,
Song, Xinhua,
Liu, Ye,
Li, Lei,
Jia, Jiaoyuan,
Pilo, Maria G.,
Wang, Jingxiao,
Cigliano, Antonio ,
Ma, Zhilong,
Kuang, Wenhua,
Tang, Zefang,
Zhang, Zemin,
Shui, Guanghou,
Ribback, Silvia,
Dombrowski, Frank,
Evert, Matthias,
Pascale, Rosa Maria,
Cossu, Carla,
Pes, Giovanni Mario ,
Osborne, Timothy F.,
Calvisi, Diego F.,
Chen, Xin und
Chen, Ligong
(2019)
Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans.
Gut 69 (1), S. 177-186.
Volltext nicht vorhanden.
Wang, Jingxiao ,
Wang, Haichuan ,
Peters, Michele,
Ding, Ning,
Ribback, Silvia,
Utpatel, Kirsten,
Cigliano, Antonio,
Dombrowski, Frank,
Xu, Meng,
Chen, Xinyan,
Song, Xinhua,
Che, Li,
Evert, Matthias,
Cossu, Antonio,
Gordan, John,
Zeng, Yong,
Chen, Xin und
Calvisi, Diego F.
(2019)
Loss of Fbxw7 synergizes with activated Akt signaling to promote c-Myc dependent cholangiocarcinogenesis.
Journal of Hepatology 71 (4), S. 742-752.
Volltext nicht vorhanden.
Wang, Pan,
Song, Xinhua,
Utpatel, Kirsten,
Shang, Runze,
Yang, Yoon Mee,
Xu, Meng,
Zhang, Jie,
Che, Li,
Gordan, John,
Cigliano, Antonio,
Seki, Ekihiro ,
Evert, Matthias,
Calvisi, Diego F.,
Hu, Xiaosong und
Chen, Xin
(2019)
MEK inhibition suppresses K-Ras wild-type cholangiocarcinoma in vitro and in vivo via inhibiting cell proliferation and modulating tumor microenvironment.
Cell Death & Disease 10 (2).
Volltext nicht vorhanden.
Xu, Meng,
Wang, Jingxiao,
Xu, Zhong,
Li, Rong,
Wang, Pan,
Shang, Runze,
Cigliano, Antonio,
Ribback, Silvia,
Solinas, Antonio ,
Pes, Giovanni Mario ,
Evert, Katja,
Wang, Haichuan,
Song, Xinhua,
Zhang, Shu,
Che, Li,
Pascale, Rosa Maria,
Calvisi, Diego F.,
Liu, Qingguang und
Chen, Xin
(2019)
SNAI1 promotes the cholangiocellular phenotype, but not epithelial-mesenchymal transition, in a murine hepatocellular carcinoma model.
Cancer Research 79 (21), S. 5563-5574.
Volltext nicht vorhanden.
Xu, Zhong,
Xu, Meng,
Liu, Pin,
Zhang, Shu,
Shang, Runze,
Qiao, Yu,
Che, Li,
Ribback, Silvia,
Cigliano, Antonio,
Evert, Katja,
Pascale, Rosa M.,
Dombrowski, Frank,
Evert, Matthias,
Chen, Xi,
Calvisi, Diego F. und
Chen, Xin
(2019)
The mTORC2‐Akt1 Cascade Is Crucial for c‐Myc to Promote Hepatocarcinogenesis in Mice and Humans.
Hepatology 70 (5), S. 1600-1613.
Volltext nicht vorhanden.
Song, Xinhua,
Liu, Xianqiong,
Wang, Haichuan ,
Wang, Jingxiao ,
Qiao, Yu,
Cigliano, Antonio,
Utpatel, Kirsten,
Ribback, Silvia,
Pilo, Maria G.,
Serra, Marina,
Gordan, John D.,
Che, Li,
Zhang, Shanshan,
Cossu, Antonio,
Porcu, Alberto,
Pascale, Rosa M.,
Dombrowski, Frank,
Hu, Hongbo,
Calvisi, Diego F.,
Evert, Matthias und
Chen, Xin
(2018)
Combined CDK4/6 and Pan-mTOR Inhibition Is Synergistic Against Intrahepatic Cholangiocarcinoma.
Clinical Cancer Research 25 (1), S. 403-413.
Volltext nicht vorhanden.
Dong, Mingjie,
Liu, Xianqiong,
Evert, Katja,
Utpatel, Kirsten,
Peters, Michele,
Zhang, Shanshan,
Xu, Zhong,
Che, Li,
Cigliano, Antonio ,
Ribback, Silvia,
Dombrowski, Frank,
Cossu, Antonio,
Gordan, John,
Calvisi, Diego F.,
Evert, Matthias,
Liu, Yan und
Chen, Xin
(2018)
Efficacy of MEK inhibition in a K-Ras-driven cholangiocarcinoma preclinical model.
Cell Death & Disease 9 (2).
Volltext nicht vorhanden.
Che, Li,
Pilo, Maria G.,
Cigliano, Antonio ,
Latte, Gavinella ,
Simile, Maria M.,
Ribback, Silvia,
Dombrowski, Frank,
Evert, Matthias,
Chen, Xin und
Calvisi, Diego F.
(2017)
Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma.
Cell Cycle 16 (6), S. 499-507.
Volltext nicht vorhanden.
Zhang, Shanshan,
Song, Xinhua,
Cao, Dan,
Xu, Zhong,
Fan, Biao,
Che, Li,
Hu, Junjie,
Chen, Bin,
Dong, Mingjie,
Pilo, Maria G.,
Cigliano, Antonio ,
Evert, Katja,
Ribback, Silvia,
Dombrowski, Frank,
Pascale, Rosa M.,
Cossu, Antonio,
Vidili, Gianpaolo,
Porcu, Alberto,
Simile, Maria M.,
Pes, Giovanni M.,
Giannelli, Gianluigi,
Gordan, John,
Wei, Lixin,
Evert, Matthias,
Cong, Wenming,
Calvisi, Diego F. und
Chen, Xin
(2017)
Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice.
Journal of Hepatology 67 (6), S. 1194-1203.
Volltext nicht vorhanden.
Wang, Chunmei,
Che, Li,
Hu, Junjie,
Zhang, Shanshan,
Jiang, Lijie,
Latte, Gavinella ,
Demartis, Maria I.,
Tao, Junyan,
Gui, Bing,
Pilo, Maria G.,
Ribback, Silvia,
Dombrowski, Frank,
Evert, Matthias,
Calvisi, Diego F. und
Chen, Xin
(2016)
Activated mutant forms of PIK3CA cooperate with RasV12 or c-Met to induce liver tumour formation in mice via AKT2/mTORC1 cascade.
Liver International 36 (8), S. 1176-1186.
Volltext nicht vorhanden.
Hu, Junjie,
Che, Li,
Li, Lei,
Pilo, Maria G.,
Cigliano, Antonio ,
Ribback, Silvia,
Li, Xiaolei,
Latte, Gavinella ,
Mela, Marta,
Evert, Matthias,
Dombrowski, Frank,
Zheng, Guohua,
Chen, Xin und
Calvisi, Diego F.
(2016)
Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice.
Scientific Reports 6 (1).
Volltext nicht vorhanden.
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