Anzahl der Einträge: 25.
2022
Cigliano, Antonio,
Zhang, Shanshan,
Ribback, Silvia,
Steinmann, Sara,
Sini, Marcella,
Ament, Cindy E.,
Utpatel, Kirsten,
Song, Xinhua,
Wang, Jingxiao ![ORCID 0000-0002-6886-5698](/images/orcid_16x16.gif)
,
Pilo, Maria G.,
Berger, Fabian,
Wang, Haichuan ![ORCID 0000-0002-6886-5698](/images/orcid_16x16.gif)
,
Tao, Junyan,
Li, Xiaolei,
Pes, Giovanni M. ![ORCID 0000-0003-3265-2823](/images/orcid_16x16.gif)
,
Mancarella, Serena,
Giannelli, Gianluigi,
Dombrowski, Frank,
Evert, Matthias,
Calvisi, Diego F.,
Chen, Xin und
Evert, Katja
(2022)
The Hippo pathway effector TAZ induces intrahepatic cholangiocarcinoma in mice and is ubiquitously activated in the human disease.
Journal of Experimental & Clinical Cancer Research 41, art.no.192.
Mancarella, Serena,
Serino, Grazia,
Gigante, Isabella,
Cigliano, Antonio,
Ribback, Silvia,
Sanese, Paola ![ORCID 0000-0001-8872-7498](/images/orcid_16x16.gif)
,
Grossi, Valentina,
Simone, Cristiano,
Armentano, Raffaele,
Evert, Matthias,
Calvisi, Diego F. und
Giannelli, Gianluigi
(2022)
CD90 is regulated by notch1 and hallmarks a more aggressive intrahepatic cholangiocarcinoma phenotype.
Journal of Experimental & Clinical Cancer Research 41 (1).
Volltext nicht vorhanden.
Wang, Haichuan,
Zhang, Shanshan,
Zhang, Yi,
Jia, Jiaoyuan,
Wang, Jingxiao,
Liu, Xianqiong,
Zhang, Jie,
Song, Xinhua,
Ribback, Silvia,
Cigliano, Antonio,
Evert, Matthias,
Liang, Bingyong,
Wu, Hong,
Calvisi, Diego F.,
Zeng, Yong und
Chen, Xin
(2022)
TAZ is indispensable for c-MYC-induced hepatocarcinogenesis.
Journal of Hepatology 76 (1), S. 123-134.
Volltext nicht vorhanden.
Zhang, Yi,
Xu, Hongwei,
Cui, Guofei,
Liang, Binyong,
Chen, Xiangzheng,
Ko, Sungjin,
Affo, Silvia,
Song, Xinhua,
Liao, Yi,
Feng, Jianguo,
Wang, Pan ![ORCID 0000-0002-6886-5698](/images/orcid_16x16.gif)
,
Wang, Haichuan ![ORCID 0000-0002-6886-5698](/images/orcid_16x16.gif)
,
Xu, Meng,
Wang, Jingxiao ![ORCID 0000-0002-6886-5698](/images/orcid_16x16.gif)
,
Pes, Giovanni M. ![ORCID 0000-0003-3265-2823](/images/orcid_16x16.gif)
,
Ribback, Silvia,
Zeng, Yong,
Singhi, Aatur,
Schwabe, Robert F.,
Monga, Satdarshan P.,
Evert, Matthias,
Tang, Liling,
Calvisi, Diego F. und
Chen, Xin
(2022)
β-Catenin Sustains and Is Required for YES-associated Protein Oncogenic Activity in Cholangiocarcinoma.
Gastroenterology 163 (2), S. 481-494.
Volltext nicht vorhanden.
2021
Wang, Haichuan ![ORCID 0000-0002-6886-5698](/images/orcid_16x16.gif)
,
Wang, Jingxiao ![ORCID 0000-0002-6886-5698](/images/orcid_16x16.gif)
,
Zhang, Shanshan,
Jia, Jiaoyuan,
Liu, Xianqiong,
Zhang, Jie,
Wang, Pan ![ORCID 0000-0002-6886-5698](/images/orcid_16x16.gif)
,
Song, Xinhua,
Che, Li,
Liu, Ke,
Ribback, Silvia,
Cigliano, Antonio ![ORCID 0000-0002-6408-3613](/images/orcid_16x16.gif)
,
Evert, Matthias,
Wu, Hong,
Calvisi, Diego F.,
Zeng, Yong und
Chen, Xin
(2021)
Distinct and Overlapping Roles of Hippo Effectors YAP and TAZ During Human and Mouse Hepatocarcinogenesis.
Cellular and Molecular Gastroenterology and Hepatology 11 (4), S. 1095-1117.
Volltext nicht vorhanden.
Pocaterra, Arianna,
Scattolin, Gloria ![ORCID 0000-0002-4784-3932](/images/orcid_16x16.gif)
,
Romani, Patrizia,
Ament, Cindy,
Ribback, Silvia,
Chen, Xin,
Evert, Matthias,
Calvisi, Diego F. und
Dupont, Sirio ![ORCID 0000-0002-6869-1966](/images/orcid_16x16.gif)
(2021)
Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development.
Communications Biology 4 (1).
Volltext nicht vorhanden.
Song, Xinhua,
Xu, Hongwei,
Wang, Pan ![ORCID 0000-0002-6886-5698](/images/orcid_16x16.gif)
,
Wang, Jingxiao ![ORCID 0000-0002-6886-5698](/images/orcid_16x16.gif)
,
Affo, Silvia ![ORCID 0000-0002-9731-3913](/images/orcid_16x16.gif)
,
Wang, Haichuan ![ORCID 0000-0002-6886-5698](/images/orcid_16x16.gif)
,
Xu, Meng,
Liang, Binyong,
Che, Li,
Qiu, Wei ![ORCID 0000-0001-8093-3094](/images/orcid_16x16.gif)
,
Schwabe, Robert F.,
Chang, Tammy T.,
Vogl, Marion,
Pes, Giovanni M. ![ORCID 0000-0003-3265-2823](/images/orcid_16x16.gif)
,
Ribback, Silvia,
Evert, Matthias,
Chen, Xin und
Calvisi, Diego F.
(2021)
Focal adhesion kinase (FAK) promotes cholangiocarcinoma development and progression via YAP activation.
Journal of Hepatology 75 (4), S. 888-899.
Volltext nicht vorhanden.
Nuernberger, Vincent,
Mortoga, Sharif,
Metzendorf, Christoph,
Burkert, Christian,
Ehricke, Katrina,
Knuth, Elisa,
Zimmer, Jenny,
Singer, Stephan,
Nath, Neetika,
Karim, Majedul,
Yasser, Mohd,
Calvisi, Diego F.,
Dombrowski, Frank und
Ribback, Silvia
(2021)
Hormonally Induced Hepatocellular Carcinoma in Diabetic Wild Type and Carbohydrate Responsive Element Binding Protein Knockout Mice.
Cells 10 (10), S. 2787.
Volltext nicht vorhanden.
Wang, Haichuan ![ORCID 0000-0002-6886-5698](/images/orcid_16x16.gif)
,
Song, Xinhua,
Liao, Haotian,
Wang, Pan ![ORCID 0000-0002-6886-5698](/images/orcid_16x16.gif)
,
Zhang, Yi,
Che, Li,
Zhang, Jie,
Zhou, Yi,
Cigliano, Antonio,
Ament, Cindy,
Superville, Daphne,
Ribback, Silvia,
Reeves, Melissa,
Pes, Giovanni M. ![ORCID 0000-0003-3265-2823](/images/orcid_16x16.gif)
,
Liang, Binyong,
Wu, Hong,
Evert, Matthias,
Calvisi, Diego F.,
Zeng, Yong und
Chen, Xin
(2021)
Overexpression of Mothers Against Decapentaplegic Homolog 7 Activates the Yes‐Associated Protein/NOTCH Cascade and Promotes Liver Carcinogenesis in Mice and Humans.
Hepatology 74 (1), S. 248-263.
Volltext nicht vorhanden.
Lu, Xinjun,
Peng, Baogang,
Chen, Ge,
Pes, Mario G. ![ORCID 0000-0003-3265-2823](/images/orcid_16x16.gif)
,
Ribback, Silvia,
Ament, Cindy ![ORCID 0000-0002-0312-3116](/images/orcid_16x16.gif)
,
Xu, Hongwei,
Pal, Rajesh ![ORCID 0000-0001-9083-4030](/images/orcid_16x16.gif)
,
Rodrigues, Pedro M. ![ORCID 0000-0001-6193-7436](/images/orcid_16x16.gif)
,
Banales, Jesus M.,
Evert, Matthias,
Calvisi, Diego F.,
Chen, Xin,
Fan, Biao und
Wang, Jingxiao
(2021)
YAP Accelerates Notch-Driven Cholangiocarcinogenesis via mTORC1 in Mice.
The American Journal of Pathology 191 (9), S. 1651-1667.
Volltext nicht vorhanden.
2020
Mancarella, Serena,
Serino, Grazia,
Dituri, Francesco,
Cigliano, Antonio ![ORCID 0000-0002-6408-3613](/images/orcid_16x16.gif)
,
Ribback, Silvia,
Wang, Jingxiao,
Chen, Xin,
Calvisi, Diego F. und
Giannelli, Gianluigi
(2020)
Crenigacestat, a selective NOTCH1 inhibitor, reduces intrahepatic cholangiocarcinoma progression by blocking VEGFA/DLL4/MMP13 axis.
Cell Death & Differentiation 27 (8), S. 2330-2343.
Volltext nicht vorhanden.
Jia, Jiaoyuan,
Che, Li,
Cigliano, Antonio ![ORCID 0000-0002-6408-3613](/images/orcid_16x16.gif)
,
Wang, Xue,
Peitta, Graziella,
Tao, Junyan,
Zhong, Sheng,
Ribback, Silvia,
Evert, Matthias,
Chen, Xin ![ORCID 0000-0002-9588-0164](/images/orcid_16x16.gif)
und
Calvisi, Diego F.
(2020)
Pivotal Role of Fatty Acid Synthase in c-MYC Driven Hepatocarcinogenesis.
International Journal of Molecular Sciences 21 (22), S. 8467.
Volltext nicht vorhanden.
Metzendorf, Christoph ![ORCID 0000-0003-3891-2809](/images/orcid_16x16.gif)
,
Wineberger, Katharina,
Rausch, Jenny,
Cigliano, Antonio ![ORCID 0000-0002-6408-3613](/images/orcid_16x16.gif)
,
Peters, Kristin,
Sun, Baodong,
Mennerich, Daniela,
Kietzmann, Thomas,
Calvisi, Diego F.,
Dombrowski, Frank und
Ribback, Silvia
(2020)
Transcriptomic and Proteomic Analysis of Clear Cell Foci (CCF) in the Human Non-Cirrhotic Liver Identifies Several Differentially Expressed Genes and Proteins with Functions in Cancer Cell Biology and Glycogen Metabolism.
Molecules 25 (18), S. 4141.
Volltext nicht vorhanden.
2019
Che, Li,
Chi, Wenna,
Qiao, Yu,
Zhang, Jie,
Song, Xinhua,
Liu, Ye,
Li, Lei,
Jia, Jiaoyuan,
Pilo, Maria G.,
Wang, Jingxiao,
Cigliano, Antonio ![ORCID 0000-0002-6408-3613](/images/orcid_16x16.gif)
,
Ma, Zhilong,
Kuang, Wenhua,
Tang, Zefang,
Zhang, Zemin,
Shui, Guanghou,
Ribback, Silvia,
Dombrowski, Frank,
Evert, Matthias,
Pascale, Rosa Maria,
Cossu, Carla,
Pes, Giovanni Mario ![ORCID 0000-0003-3265-2823](/images/orcid_16x16.gif)
,
Osborne, Timothy F.,
Calvisi, Diego F.,
Chen, Xin ![ORCID 0000-0002-7893-7173](/images/orcid_16x16.gif)
und
Chen, Ligong ![ORCID 0000-0002-7893-7173](/images/orcid_16x16.gif)
(2019)
Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans.
Gut 69 (1), S. 177-186.
Volltext nicht vorhanden.
Wang, Jingxiao ![ORCID 0000-0002-6886-5698](/images/orcid_16x16.gif)
,
Wang, Haichuan ![ORCID 0000-0002-6886-5698](/images/orcid_16x16.gif)
,
Peters, Michele,
Ding, Ning,
Ribback, Silvia,
Utpatel, Kirsten,
Cigliano, Antonio,
Dombrowski, Frank,
Xu, Meng,
Chen, Xinyan,
Song, Xinhua,
Che, Li,
Evert, Matthias,
Cossu, Antonio,
Gordan, John,
Zeng, Yong,
Chen, Xin und
Calvisi, Diego F.
(2019)
Loss of Fbxw7 synergizes with activated Akt signaling to promote c-Myc dependent cholangiocarcinogenesis.
Journal of Hepatology 71 (4), S. 742-752.
Volltext nicht vorhanden.
Xu, Meng,
Wang, Jingxiao,
Xu, Zhong,
Li, Rong,
Wang, Pan,
Shang, Runze,
Cigliano, Antonio,
Ribback, Silvia,
Solinas, Antonio ![ORCID 0000-0002-5537-6692](/images/orcid_16x16.gif)
,
Pes, Giovanni Mario ![ORCID 0000-0003-3265-2823](/images/orcid_16x16.gif)
,
Evert, Katja,
Wang, Haichuan,
Song, Xinhua,
Zhang, Shu,
Che, Li,
Pascale, Rosa Maria,
Calvisi, Diego F.,
Liu, Qingguang und
Chen, Xin
(2019)
SNAI1 promotes the cholangiocellular phenotype, but not epithelial-mesenchymal transition, in a murine hepatocellular carcinoma model.
Cancer Research 79 (21), S. 5563-5574.
Volltext nicht vorhanden.
Xu, Zhong,
Xu, Meng,
Liu, Pin,
Zhang, Shu,
Shang, Runze,
Qiao, Yu,
Che, Li,
Ribback, Silvia,
Cigliano, Antonio,
Evert, Katja,
Pascale, Rosa M.,
Dombrowski, Frank,
Evert, Matthias,
Chen, Xi,
Calvisi, Diego F. und
Chen, Xin
(2019)
The mTORC2‐Akt1 Cascade Is Crucial for c‐Myc to Promote Hepatocarcinogenesis in Mice and Humans.
Hepatology 70 (5), S. 1600-1613.
Volltext nicht vorhanden.
2018
Song, Xinhua,
Liu, Xianqiong,
Wang, Haichuan ![ORCID 0000-0002-6886-5698](/images/orcid_16x16.gif)
,
Wang, Jingxiao ![ORCID 0000-0002-6886-5698](/images/orcid_16x16.gif)
,
Qiao, Yu,
Cigliano, Antonio,
Utpatel, Kirsten,
Ribback, Silvia,
Pilo, Maria G.,
Serra, Marina,
Gordan, John D.,
Che, Li,
Zhang, Shanshan,
Cossu, Antonio,
Porcu, Alberto,
Pascale, Rosa M.,
Dombrowski, Frank,
Hu, Hongbo,
Calvisi, Diego F.,
Evert, Matthias und
Chen, Xin
(2018)
Combined CDK4/6 and Pan-mTOR Inhibition Is Synergistic Against Intrahepatic Cholangiocarcinoma.
Clinical Cancer Research 25 (1), S. 403-413.
Volltext nicht vorhanden.
Dong, Mingjie,
Liu, Xianqiong,
Evert, Katja,
Utpatel, Kirsten,
Peters, Michele,
Zhang, Shanshan,
Xu, Zhong,
Che, Li,
Cigliano, Antonio ![ORCID 0000-0002-6408-3613](/images/orcid_16x16.gif)
,
Ribback, Silvia,
Dombrowski, Frank,
Cossu, Antonio,
Gordan, John,
Calvisi, Diego F.,
Evert, Matthias,
Liu, Yan und
Chen, Xin
(2018)
Efficacy of MEK inhibition in a K-Ras-driven cholangiocarcinoma preclinical model.
Cell Death & Disease 9 (2).
Volltext nicht vorhanden.
2017
Cigliano, Antonio ![ORCID 0000-0002-6408-3613](/images/orcid_16x16.gif)
,
Wang, Chunmei,
Pilo, Maria G.,
Szydlowska, Marta ![ORCID 0000-0002-4660-899X](/images/orcid_16x16.gif)
,
Brozzetti, Stefania ![ORCID 0000-0001-7440-4305](/images/orcid_16x16.gif)
,
Latte, Gavinella,
Pes, Giovanni M.,
Pascale, Rosa M.,
Seddaiu, Maria A.,
Vidili, Gianpaolo,
Ribback, Silvia,
Dombrowski, Frank,
Evert, Matthias,
Chen, Xin und
Calvisi, Diego F.
(2017)
Inhibition of HSF1 suppresses the growth of hepatocarcinoma cell lines <i>in vitro</i> and AKT-driven hepatocarcinogenesis in mice.
Oncotarget 8 (33).
Volltext nicht vorhanden.
Che, Li,
Pilo, Maria G.,
Cigliano, Antonio ![ORCID 0000-0002-6408-3613](/images/orcid_16x16.gif)
,
Latte, Gavinella ![ORCID 0000-0003-0728-8361](/images/orcid_16x16.gif)
,
Simile, Maria M.,
Ribback, Silvia,
Dombrowski, Frank,
Evert, Matthias,
Chen, Xin und
Calvisi, Diego F.
(2017)
Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma.
Cell Cycle 16 (6), S. 499-507.
Volltext nicht vorhanden.
Zhang, Shanshan,
Song, Xinhua,
Cao, Dan,
Xu, Zhong,
Fan, Biao,
Che, Li,
Hu, Junjie,
Chen, Bin,
Dong, Mingjie,
Pilo, Maria G.,
Cigliano, Antonio ![ORCID 0000-0002-6408-3613](/images/orcid_16x16.gif)
,
Evert, Katja,
Ribback, Silvia,
Dombrowski, Frank,
Pascale, Rosa M.,
Cossu, Antonio,
Vidili, Gianpaolo,
Porcu, Alberto,
Simile, Maria M.,
Pes, Giovanni M.,
Giannelli, Gianluigi,
Gordan, John,
Wei, Lixin,
Evert, Matthias,
Cong, Wenming,
Calvisi, Diego F. und
Chen, Xin
(2017)
Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice.
Journal of Hepatology 67 (6), S. 1194-1203.
Volltext nicht vorhanden.
2016
Wang, Chunmei,
Che, Li,
Hu, Junjie,
Zhang, Shanshan,
Jiang, Lijie,
Latte, Gavinella ![ORCID 0000-0003-0728-8361](/images/orcid_16x16.gif)
,
Demartis, Maria I.,
Tao, Junyan,
Gui, Bing,
Pilo, Maria G.,
Ribback, Silvia,
Dombrowski, Frank,
Evert, Matthias,
Calvisi, Diego F. und
Chen, Xin
(2016)
Activated mutant forms of PIK3CA cooperate with RasV12 or c-Met to induce liver tumour formation in mice via AKT2/mTORC1 cascade.
Liver International 36 (8), S. 1176-1186.
Volltext nicht vorhanden.
Hu, Junjie,
Che, Li,
Li, Lei,
Pilo, Maria G.,
Cigliano, Antonio ![ORCID 0000-0002-6408-3613](/images/orcid_16x16.gif)
,
Ribback, Silvia,
Li, Xiaolei,
Latte, Gavinella ![ORCID 0000-0003-0728-8361](/images/orcid_16x16.gif)
,
Mela, Marta,
Evert, Matthias,
Dombrowski, Frank,
Zheng, Guohua,
Chen, Xin und
Calvisi, Diego F.
(2016)
Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice.
Scientific Reports 6 (1).
Volltext nicht vorhanden.
Diese Liste wurde erzeugt am Fri Aug 16 22:58:15 2024 CEST.