Entries of Cigliano, Antonio on the publication server

Steinmann, Sara M. , Lazzari, Melania, Kleinle, Augustinus, Pischedda, Dora, Cigliano, Antonio , Galleri, Grazia, Siegmund, Heiko, Fischer, Claudia, Piscuoglio, Salvatore , Evert, Matthias and Calvisi, Diego F. (2026) The Novel HSF1 Inhibitor NXP800 Exhibits Robust Antitumor Activity in Hepatocellular Carcinoma. International Journal of Molecular Sciences 27 (6), p. 2781.

Cigliano, Antonio , Simile, Maria M., Vidili, Gianpaolo, Pes, Giovanni M., Dore, Maria P., Urigo, Francesco, Cossu, Eleonora, Che, Li, Feo, Claudio, Steinmann, Sara M. , Ribback, Silvia, Pascale, Rosa M., Evert, Matthias, Chen, Xin and Calvisi, Diego F. (2024) Fatty Acid Synthase Promotes Hepatocellular Carcinoma Growth via S-Phase Kinase-Associated Protein 2/p27KIP1 Regulation. Medicina 60 (7), p. 1160.

Steinmann, Sara M. , Sánchez-Martín, Anabel, Tanzer, Elisabeth, Cigliano, Antonio , Pes, Giovanni M. , Simile, Maria M., Desaubry, Laurent, Marin, Jose J.G. , Evert, Matthias and Calvisi, Diego F. (2023) eIF4A1 Is a Prognostic Marker and Actionable Target in Human Hepatocellular Carcinoma. International Journal of Molecular Sciences 24 (3), p. 2055. Fulltext not available.

Cigliano, Antonio, Zhang, Shanshan, Ribback, Silvia, Steinmann, Sara, Sini, Marcella, Ament, Cindy E., Utpatel, Kirsten, Song, Xinhua, Wang, Jingxiao , Pilo, Maria G., Berger, Fabian, Wang, Haichuan , Tao, Junyan, Li, Xiaolei, Pes, Giovanni M. , Mancarella, Serena, Giannelli, Gianluigi, Dombrowski, Frank, Evert, Matthias, Calvisi, Diego F., Chen, Xin and Evert, Katja (2022) The Hippo pathway effector TAZ induces intrahepatic cholangiocarcinoma in mice and is ubiquitously activated in the human disease. Journal of Experimental & Clinical Cancer Research 41, art.no.192.

Mancarella, Serena, Serino, Grazia, Gigante, Isabella, Cigliano, Antonio, Ribback, Silvia, Sanese, Paola , Grossi, Valentina, Simone, Cristiano, Armentano, Raffaele, Evert, Matthias, Calvisi, Diego F. and Giannelli, Gianluigi (2022) CD90 is regulated by notch1 and hallmarks a more aggressive intrahepatic cholangiocarcinoma phenotype. Journal of Experimental & Clinical Cancer Research 41 (1). Fulltext not available.

Wang, Haichuan, Zhang, Shanshan, Zhang, Yi, Jia, Jiaoyuan, Wang, Jingxiao, Liu, Xianqiong, Zhang, Jie, Song, Xinhua, Ribback, Silvia, Cigliano, Antonio, Evert, Matthias, Liang, Bingyong, Wu, Hong, Calvisi, Diego F., Zeng, Yong and Chen, Xin (2022) TAZ is indispensable for c-MYC-induced hepatocarcinogenesis. Journal of Hepatology 76 (1), pp. 123-134. Fulltext not available.

Scheiter, Alexander, Evert, Katja , Reibenspies, Lucas, Cigliano, Antonio , Annweiler, Katharina, Müller, Karolina , Pöhmerer, Laura-Maria-Giovanna, Xu, Hongwei, Cui, Guofei, Itzel, Timo, Materna-Reichelt, Silvia, Coluccio, Andrea, Honarnejad, Kamran, Teufel, Andreas, Brochhausen, Christoph , Dombrowski, Frank, Chen, Xin, Evert, Matthias, Calvisi, Diego F. and Utpatel, Kirsten (2021) RASSF1A independence and early galectin-1 upregulation in PIK3CA-induced hepatocarcinogenesis: new therapeutic venues. Molecular Oncology 16 (5), pp. 1091-1118.

Cigliano, Antonio, Chen, Xin and Calvisi, Diego F. (2021) Current challenges to underpinning the genetic basis for cholangiocarcinoma. Expert Review of Gastroenterology & Hepatology 15 (5), pp. 511-526. Fulltext not available.

Wang, Haichuan , Wang, Jingxiao , Zhang, Shanshan, Jia, Jiaoyuan, Liu, Xianqiong, Zhang, Jie, Wang, Pan , Song, Xinhua, Che, Li, Liu, Ke, Ribback, Silvia, Cigliano, Antonio , Evert, Matthias, Wu, Hong, Calvisi, Diego F., Zeng, Yong and Chen, Xin (2021) Distinct and Overlapping Roles of Hippo Effectors YAP and TAZ During Human and Mouse Hepatocarcinogenesis. Cellular and Molecular Gastroenterology and Hepatology 11 (4), pp. 1095-1117. Fulltext not available.

Wang, Haichuan , Song, Xinhua, Liao, Haotian, Wang, Pan , Zhang, Yi, Che, Li, Zhang, Jie, Zhou, Yi, Cigliano, Antonio, Ament, Cindy, Superville, Daphne, Ribback, Silvia, Reeves, Melissa, Pes, Giovanni M. , Liang, Binyong, Wu, Hong, Evert, Matthias, Calvisi, Diego F., Zeng, Yong and Chen, Xin (2021) Overexpression of Mothers Against Decapentaplegic Homolog 7 Activates the Yes‐Associated Protein/NOTCH Cascade and Promotes Liver Carcinogenesis in Mice and Humans. Hepatology 74 (1), pp. 248-263. Fulltext not available.

Shang, Runze, Song, Xinhua, Wang, Pan, Zhou, Yi, Lu, Xinjun, Wang, Jingxiao, Xu, Meng, Chen, Xinyan, Utpatel, Kirsten, Che, Li, Liang, Binyong, Cigliano, Antonio, Evert, Matthias, Calvisi, Diego F. and Chen, Xin (2020) Cabozantinib-based combination therapy for the treatment of hepatocellular carcinoma. Gut 70 (9), pp. 1746-1757. Fulltext not available.

Mancarella, Serena, Serino, Grazia, Dituri, Francesco, Cigliano, Antonio , Ribback, Silvia, Wang, Jingxiao, Chen, Xin, Calvisi, Diego F. and Giannelli, Gianluigi (2020) Crenigacestat, a selective NOTCH1 inhibitor, reduces intrahepatic cholangiocarcinoma progression by blocking VEGFA/DLL4/MMP13 axis. Cell Death & Differentiation 27 (8), pp. 2330-2343. Fulltext not available.

Cigliano, Antonio , Pilo, M. G., Mela, M., Evert, Matthias, Calvisi, Diego F., Utpatel, Kirsten , make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference and make_name_string expected hash reference (2020) Inhibition of MELK Protooncogene as an Innovative Treatment for Intrahepatic Cholangiocarcinoma. Medicina 56, p. 1.

Jia, Jiaoyuan, Che, Li, Cigliano, Antonio , Wang, Xue, Peitta, Graziella, Tao, Junyan, Zhong, Sheng, Ribback, Silvia, Evert, Matthias, Chen, Xin and Calvisi, Diego F. (2020) Pivotal Role of Fatty Acid Synthase in c-MYC Driven Hepatocarcinogenesis. International Journal of Molecular Sciences 21 (22), p. 8467. Fulltext not available.

Zhang, Shu, Zhang, Jie, Evert, Katja, Li, Xiaolei, Liu, Pin, Kiss, Andras, Schaff, Zsuzsa, Ament, Cindy , Zhang, Yi, Serra, Monica, Evert, Matthias, Chen, Nianyong, Xu, Feng, Chen, Xin, Tao, Junyan, Calvisi, Diego F. and Cigliano, Antonio (2020) The Hippo Effector Transcriptional Coactivator with PDZ-Binding Motif Cooperates with Oncogenic β-Catenin to Induce Hepatoblastoma Development in Mice and Humans. The American Journal of Pathology 190 (7), pp. 1397-1413. Fulltext not available.

Metzendorf, Christoph , Wineberger, Katharina, Rausch, Jenny, Cigliano, Antonio , Peters, Kristin, Sun, Baodong, Mennerich, Daniela, Kietzmann, Thomas, Calvisi, Diego F., Dombrowski, Frank and Ribback, Silvia (2020) Transcriptomic and Proteomic Analysis of Clear Cell Foci (CCF) in the Human Non-Cirrhotic Liver Identifies Several Differentially Expressed Genes and Proteins with Functions in Cancer Cell Biology and Glycogen Metabolism. Molecules 25 (18), p. 4141. Fulltext not available.

Che, Li, Paliogiannis, Panagiotis, Cigliano, Antonio , Pilo, Maria G., Chen, Xin and Calvisi, Diego F. (2019) Pathogenetic, Prognostic, and Therapeutic Role of Fatty Acid Synthase in Human Hepatocellular Carcinoma. Frontiers in Oncology 9 (1412), pp. 1-10.

Che, Li, Chi, Wenna, Qiao, Yu, Zhang, Jie, Song, Xinhua, Liu, Ye, Li, Lei, Jia, Jiaoyuan, Pilo, Maria G., Wang, Jingxiao, Cigliano, Antonio , Ma, Zhilong, Kuang, Wenhua, Tang, Zefang, Zhang, Zemin, Shui, Guanghou, Ribback, Silvia, Dombrowski, Frank, Evert, Matthias, Pascale, Rosa Maria, Cossu, Carla, Pes, Giovanni Mario , Osborne, Timothy F., Calvisi, Diego F., Chen, Xin and Chen, Ligong (2019) Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans. Gut 69 (1), pp. 177-186. Fulltext not available.

Wang, Jingxiao , Wang, Haichuan , Peters, Michele, Ding, Ning, Ribback, Silvia, Utpatel, Kirsten, Cigliano, Antonio, Dombrowski, Frank, Xu, Meng, Chen, Xinyan, Song, Xinhua, Che, Li, Evert, Matthias, Cossu, Antonio, Gordan, John, Zeng, Yong, Chen, Xin and Calvisi, Diego F. (2019) Loss of Fbxw7 synergizes with activated Akt signaling to promote c-Myc dependent cholangiocarcinogenesis. Journal of Hepatology 71 (4), pp. 742-752. Fulltext not available.

Wang, Pan, Song, Xinhua, Utpatel, Kirsten, Shang, Runze, Yang, Yoon Mee, Xu, Meng, Zhang, Jie, Che, Li, Gordan, John, Cigliano, Antonio, Seki, Ekihiro , Evert, Matthias, Calvisi, Diego F., Hu, Xiaosong and Chen, Xin (2019) MEK inhibition suppresses K-Ras wild-type cholangiocarcinoma in vitro and in vivo via inhibiting cell proliferation and modulating tumor microenvironment. Cell Death & Disease 10 (2). Fulltext not available.

Xu, Meng, Wang, Jingxiao, Xu, Zhong, Li, Rong, Wang, Pan, Shang, Runze, Cigliano, Antonio, Ribback, Silvia, Solinas, Antonio , Pes, Giovanni Mario , Evert, Katja, Wang, Haichuan, Song, Xinhua, Zhang, Shu, Che, Li, Pascale, Rosa Maria, Calvisi, Diego F., Liu, Qingguang and Chen, Xin (2019) SNAI1 promotes the cholangiocellular phenotype, but not epithelial-mesenchymal transition, in a murine hepatocellular carcinoma model. Cancer Research 79 (21), pp. 5563-5574. Fulltext not available.

Xu, Zhong, Xu, Meng, Liu, Pin, Zhang, Shu, Shang, Runze, Qiao, Yu, Che, Li, Ribback, Silvia, Cigliano, Antonio, Evert, Katja, Pascale, Rosa M., Dombrowski, Frank, Evert, Matthias, Chen, Xi, Calvisi, Diego F. and Chen, Xin (2019) The mTORC2‐Akt1 Cascade Is Crucial for c‐Myc to Promote Hepatocarcinogenesis in Mice and Humans. Hepatology 70 (5), pp. 1600-1613. Fulltext not available.

Song, Xinhua, Liu, Xianqiong, Wang, Haichuan , Wang, Jingxiao , Qiao, Yu, Cigliano, Antonio, Utpatel, Kirsten, Ribback, Silvia, Pilo, Maria G., Serra, Marina, Gordan, John D., Che, Li, Zhang, Shanshan, Cossu, Antonio, Porcu, Alberto, Pascale, Rosa M., Dombrowski, Frank, Hu, Hongbo, Calvisi, Diego F., Evert, Matthias and Chen, Xin (2018) Combined CDK4/6 and Pan-mTOR Inhibition Is Synergistic Against Intrahepatic Cholangiocarcinoma. Clinical Cancer Research 25 (1), pp. 403-413. Fulltext not available.

Dong, Mingjie, Liu, Xianqiong, Evert, Katja, Utpatel, Kirsten, Peters, Michele, Zhang, Shanshan, Xu, Zhong, Che, Li, Cigliano, Antonio , Ribback, Silvia, Dombrowski, Frank, Cossu, Antonio, Gordan, John, Calvisi, Diego F., Evert, Matthias, Liu, Yan and Chen, Xin (2018) Efficacy of MEK inhibition in a K-Ras-driven cholangiocarcinoma preclinical model. Cell Death & Disease 9 (2). Fulltext not available.

Cigliano, Antonio , Wang, Chunmei, Pilo, Maria G., Szydlowska, Marta , Brozzetti, Stefania , Latte, Gavinella, Pes, Giovanni M., Pascale, Rosa M., Seddaiu, Maria A., Vidili, Gianpaolo, Ribback, Silvia, Dombrowski, Frank, Evert, Matthias, Chen, Xin and Calvisi, Diego F. (2017) Inhibition of HSF1 suppresses the growth of hepatocarcinoma cell lines <i>in vitro</i> and AKT-driven hepatocarcinogenesis in mice. Oncotarget 8 (33). Fulltext not available.

Che, Li, Pilo, Maria G., Cigliano, Antonio , Latte, Gavinella , Simile, Maria M., Ribback, Silvia, Dombrowski, Frank, Evert, Matthias, Chen, Xin and Calvisi, Diego F. (2017) Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma. Cell Cycle 16 (6), pp. 499-507. Fulltext not available.

Zhang, Shanshan, Song, Xinhua, Cao, Dan, Xu, Zhong, Fan, Biao, Che, Li, Hu, Junjie, Chen, Bin, Dong, Mingjie, Pilo, Maria G., Cigliano, Antonio , Evert, Katja, Ribback, Silvia, Dombrowski, Frank, Pascale, Rosa M., Cossu, Antonio, Vidili, Gianpaolo, Porcu, Alberto, Simile, Maria M., Pes, Giovanni M., Giannelli, Gianluigi, Gordan, John, Wei, Lixin, Evert, Matthias, Cong, Wenming, Calvisi, Diego F. and Chen, Xin (2017) Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice. Journal of Hepatology 67 (6), pp. 1194-1203. Fulltext not available.

Hu, Junjie, Che, Li, Li, Lei, Pilo, Maria G., Cigliano, Antonio , Ribback, Silvia, Li, Xiaolei, Latte, Gavinella , Mela, Marta, Evert, Matthias, Dombrowski, Frank, Zheng, Guohua, Chen, Xin and Calvisi, Diego F. (2016) Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice. Scientific Reports 6 (1). Fulltext not available.