Einträge von Pockes, Steffen auf dem Publikationsserver

Lier, Constantin, Kees, Frieder , Witowski, Andrea, Rahmel, Tim, Pockes, Steffen und Dorn, Christoph (2025) Simultaneous determination of ceftazidime and avibactam in patients by isocratic ion-pair liquid chromatography with photometric detection. Journal of Chromatography Open 7, S. 100212.

Walter, Melanie, Bresinsky, Merlin, Zimmer, Oliver , Pockes, Steffen und Goepferich, Achim (2024) Conditional Cell-Penetrating Peptide Exposure as Selective Nanoparticle Uptake Signal. ACS Applied Materials & Interfaces 16 (29), S. 37734-37747.

Nagl, Martin, Moennich, Denise, Rosier, Niklas , Schihada, Hannes, Sirbu, Alexei, Konar, Nergis, Reyes-Resina, Irene, Navarro, Gemma, Franco, Rafael, Kolb, Peter, Annibale, Paolo und Pockes, Steffen (2023) Fluorescent Tools for the Imaging of Dopamine D2‐Like Receptors. ChemBioChem.

Rosier, Niklas , Moennich, Denise, Nagl, Martin, Schihada, Hannes, Sirbu, Alexei, Konar, Nergis, Reyes-Resina, Irene, Navarro, Gemma, Franco, Rafael, Kolb, Peter, Annibale, Paolo und Pockes, Steffen (2023) Shedding Light on the D1‐Like Receptors: A Fluorescence‐Based Toolbox for Visualization of the D1 and D5 Receptors. ChemBioChem.

Cuellar, Matthew E., Yang, Mu , Karavadhi, Surendra, Zhang, Ya-Qin, Zhu, Hu, Sun, Hongmao, Shen, Min, Hall, Matthew D., Patnaik, Samarjit, Ashe, Karen H., Walters, Michael A. und Pockes, Steffen (2023) An electrophilic fragment screening for the development of small molecules targeting caspase-2. European Journal of Medicinal Chemistry 259, S. 115632. Volltext nicht vorhanden.

Bresinsky, Merlin, Shahraki, Aida , Kolb, Peter , Pockes, Steffen und Schihada, Hannes (2023) Development of Fluorescent AF64394 Analogues Enables Real-Time Binding Studies for the Orphan Class A GPCR GPR3. Journal of Medicinal Chemistry 66 (21), S. 15025-15041. Volltext nicht vorhanden.

Mönnich, Denise, Nagl, Martin, Forster, Lisa, Rosier, Niklas, Igel, Patrick und Pockes, Steffen (2023) Discovery of a Tritiated Radioligand with High Affinity and Selectivity for the Histamine H3 Receptor. ACS Medicinal Chemistry Letters 14 (11), S. 1589-1595. Volltext nicht vorhanden.

Szczepańska, Katarzyna, Karcz, Tadeusz, Dichiara, Maria, Mogilski, Szczepan, Kalinowska-Tłuścik, Justyna, Pilarski, Bogusław, Leniak, Arkadiusz, Pietruś, Wojciech , Podlewska, Sabina , Popiołek-Barczyk, Katarzyna, Humphrys, Laura J. , Ruiz-Cantero, M. Carmen, Reiner-Link, David , Leitzbach, Luisa, Łażewska, Dorota, Pockes, Steffen , Górka, Michał, Zmysłowski, Adam, Calmels, Thierry, Cobos, Enrique J., Marrazzo, Agostino, Stark, Holger, Bojarski, Andrzej J., Amata, Emanuele und Kieć-Kononowicz, Katarzyna (2023) Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain. Journal of Medicinal Chemistry 66 (14), S. 9658-9683. Volltext nicht vorhanden.

Jacob, Hannes, Braekow, Pauline, Hofmann, Britt, Kirchhefer, Uwe, Forster, Lisa, Mönnich, Denise, Humphrys, Laura J., Pockes, Steffen, Neumann, Joachim und Gergs, Ulrich (2023) Ergometrine stimulates histamine H2 receptors in the isolated human atrium. Naunyn-Schmiedeberg's Archives of Pharmacology 396 (12), S. 3809-3822. Volltext nicht vorhanden.

Pockes, Steffen , Walters, Michael A. und Ashe, Karen H. (2023) Targeting caspase-2 interactions with tau in Alzheimer's disease and related dementias. Translational Research 254, S. 34-40. Volltext nicht vorhanden.

Forster, Lisa und Pockes, Steffen (2022) Investigating the ligand agonism and antagonism at the D2long receptor by dynamic mass redistribution. Scientific Reports 12 (1).

Bresinsky, Merlin, Strasser, Jessica M., Hubmann, Alexander, Vallaster, Bernadette, McCue, William M., Fuller, Jessica, Singh, Gurpreet, Nelson, Kathryn M., Cuellar, Matthew E., Finzel, Barry C., Ashe, Karen H., Walters, Michael A. und Pockes, Steffen (2022) Characterization of caspase‐2 inhibitors based on specific sites of caspase‐2‐mediated proteolysis. Archiv der Pharmazie 355 (9), S. 2200095.

Singh, Gurpreet, Liu, Peng, Yao, Katherine R., Strasser, Jessica M., Hlynialuk, Chris, Leinonen-Wright, Kailee, Teravskis, Peter J., Choquette, Jessica M., Ikramuddin, Junaid, Bresinsky, Merlin, Nelson, Kathryn M., Liao, Dezhi, Ashe, Karen H., Walters, Michael A. und Pockes, Steffen (2022) Caspase-2 Inhibitor Blocks Tau Truncation and Restores Excitatory Neurotransmission in Neurons Modeling FTDP-17 Tauopathy. ACS Chemical Neuroscience 13 (10), S. 1549-1557. Volltext nicht vorhanden.

Szczepańska, Katarzyna, Podlewska, Sabina, Dichiara, Maria, Gentile, Davide, Patamia, Vincenzo, Rosier, Niklas, Mönnich, Denise, Ruiz Cantero, Ma Carmen, Karcz, Tadeusz, Łażewska, Dorota, Siwek, Agata, Pockes, Steffen, Cobos, Enrique J., Marrazzo, Agostino, Stark, Holger, Rescifina, Antonio, Bojarski, Andrzej J., Amata, Emanuele und Kieć-Kononowicz, Katarzyna (2022) Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H3 and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties. ACS Chemical Neuroscience 13 (1), S. 1-15. Volltext nicht vorhanden.

Pockes, Steffen und Tropmann, Katharina (2021) Histamine H2 receptor radioligands: triumphs and challenges. Future Medicinal Chemistry 13 (12), S. 1073-1081.

Rosier, Niklas, Grätz, Lukas, Schihada, Hannes , Möller, Jan, Işbilir, Ali , Humphrys, Laura J. , Nagl, Martin, Seibel, Ulla, Lohse, Martin J. und Pockes, Steffen (2021) A Versatile Sub-Nanomolar Fluorescent Ligand Enables NanoBRET Binding Studies and Single-Molecule Microscopy at the Histamine H3 Receptor. Journal of Medicinal Chemistry 64 (15), S. 11695-11708. Volltext nicht vorhanden.

Tropmann, Katharina, Bresinsky, Merlin, Forster, Lisa, Mönnich, Denise, Buschauer, Armin , Wittmann, Hans-Joachim, Hübner, Harald, Gmeiner, Peter, Pockes, Steffen und Strasser, Andrea (2021) Abolishing Dopamine D2long/D3 Receptor Affinity of Subtype-Selective Carbamoylguanidine-Type Histamine H2 Receptor Agonists. Journal of Medicinal Chemistry 64 (12), S. 8684-8709. Volltext nicht vorhanden.

Gergs, Ulrich, Büxel, Maren L., Bresinsky, Merlin, Kirchhefer, Uwe, Fehse, Charlotte, Höring, Carina, Hofmann, Britt, Marušáková, Margaréta, Čináková, Aneta, Schwarz, Rebecca, Pockes, Steffen und Neumann, Joachim (2021) Cardiac Effects of Novel Histamine H2 Receptor Agonists. Journal of Pharmacology and Experimental Therapeutics 379 (3), S. 223-234. Volltext nicht vorhanden.

Biselli, Sabrina, Bresinsky, Merlin, Tropmann, Katharina, Forster, Lisa , Honisch, Claudia , Buschauer, Armin, Bernhardt, Günther und Pockes, Steffen (2021) Pharmacological characterization of a new series of carbamoylguanidines reveals potent agonism at the H2R and D3R. European Journal of Medicinal Chemistry 214, S. 113190. Volltext nicht vorhanden.

Szczepańska, Katarzyna , Pockes, Steffen , Podlewska, Sabina, Höring, Carina, Mika, Kamil, Latacz, Gniewomir, Bednarski, Marek, Siwek, Agata , Karcz, Tadeusz, Nagl, Martin, Bresinsky, Merlin, Mönnich, Denise, Seibel, Ulla, Kuder, Kamil J. , Kotańska, Magdalena, Stark, Holger, Elz, Sigurd und Kieć-Kononowicz, Katarzyna (2021) Structural modifications in the distal, regulatory region of histamine H3 receptor antagonists leading to the identification of a potent anti-obesity agent. European Journal of Medicinal Chemistry 213, S. 113041. Volltext nicht vorhanden.

Höring, Carina , Seibel, Ulla , Tropmann, Katharina, Grätz, Lukas , Mönnich, Denise , Pitzl, Sebastian, Bernhardt, Günther , Pockes, Steffen und Strasser, Andrea (2020) A Dynamic, Split-Luciferase-Based Mini-G Protein Sensor to Functionally Characterize Ligands at All Four Histamine Receptor Subtypes. International Journal of Molecular Sciences 21 (22), S. 8440.

Grätz, Lukas, Tropmann, Katharina, Bresinsky, Merlin, Müller, Christoph, Bernhardt, Günther und Pockes, Steffen (2020) NanoBRET binding assay for histamine H2 receptor ligands using live recombinant HEK293T cells. Scientific Reports 10, S. 13288.

Forster, Lisa , Grätz, Lukas, Mönnich, Denise, Bernhardt, Günther und Pockes, Steffen (2020) A Split Luciferase Complementation Assay for the Quantification of β-Arrestin2 Recruitment to Dopamine D2-Like Receptors. International Journal of Molecular Sciences 21 (17), S. 6103.

Schihada, Hannes , Ma, Xiaoyuan, Zabel, Ulrike, Vischer, Henry F., Schulte, Gunnar , Leurs, Rob, Pockes, Steffen und Lohse, Martin J. (2020) Development of a Conformational Histamine H3 Receptor Biosensor for the Synchronous Screening of Agonists and Inverse Agonists. ACS Sensors 5 (6), S. 1734-1742. Volltext nicht vorhanden.

Tropmann, Katharina, Höring, Carina , Plank, Nicole und Pockes, Steffen (2020) Discovery of a G Protein-Biased Radioligand for the Histamine H2 Receptor with Reversible Binding Properties. Journal of Medicinal Chemistry 63 (21), S. 13090-13102. Volltext nicht vorhanden.

Pockes, Steffen, Wifling, David , Buschauer, Armin und Elz, Sigurd (2019) Structure‐Activity Relationship of Hetarylpropylguanidines Aiming at the Development of Selective Histamine Receptor Ligands †. ChemistryOpen 8 (3), S. 285-297.

Rustler, Karin , Pockes, Steffen und König, Burkhard (2019) Light-Switchable Antagonists for the Histamine H1 Receptor at the Isolated Guinea Pig Ileum. ChemMedChem 14 (6), S. 636-644. Volltext nicht vorhanden.

Rustler, Karin , Pockes, Steffen und König, Burkhard (2019) Cover Feature: Light‐Switchable Antagonists for the Histamine H 1 Receptor at the Isolated Guinea Pig Ileum (ChemMedChem 6/2019). ChemMedChem 14 (6), S. 614. Volltext nicht vorhanden.

Soliman, Beatrice, Wang, Ning, Zagotto, Giuseppe und Pockes, Steffen (2019) Synthesis and biological evaluation of heteroalicyclic cyanoguanidines at histamine receptors. Archiv der Pharmazie 352 (9), S. 1900107. Volltext nicht vorhanden.

Pockes, Steffen , Wifling, David , Keller, Max, Buschauer, Armin und Elz, Sigurd (2018) Highly Potent, Stable, and Selective Dimeric Hetarylpropylguanidine-Type Histamine H2 Receptor Agonists. ACS Omega 2018 (3), S. 2865-2882.

Pockes, Steffen (2018) Synthese und pharmakologische Charakterisierung von Heteroarylpropylguanidin-Derivaten an Histamin-Rezeptorsubtypen: Struktur-Wirkungsbeziehungen mono- und bivalenter Liganden. Dissertation, Universität Regensburg.

Sadek, Bassem, Khan, Nadia, Darras, Fouad H., Pockes, Steffen und Decker, Michael (2016) The dual-acting AChE inhibitor and H3 receptor antagonist UW-MD-72 reverses amnesia induced by scopolamine or dizocilpine in passive avoidance paradigm in rats. Physiology & Behavior 165, S. 383-391. Volltext nicht vorhanden.

Darras, Fouad, Pockes, Steffen, Huang, Guozheng , Wehle, Sarah, Strasser, Andrea, Wittmann, Hans-Joachim, Nimczick, Martin, Sotriffer, Christoph und Decker, Michael (2014) Synthesis, biological evaluation, and computational studies of tri- and tetracyclic nitrogen-bridgehead compounds as potent dual-acting AChE inhibitors and hH3 receptor antagonists. ACS Chemical Neuroscience 5 (3), S. 225-242. Volltext nicht vorhanden.