Publications by Pockes, Steffen

Nagl, Martin, Moennich, Denise, Rosier, Niklas , Schihada, Hannes, Sirbu, Alexei, Konar, Nergis, Reyes-Resina, Irene, Navarro, Gemma, Franco, Rafael, Kolb, Peter, Annibale, Paolo and Pockes, Steffen (2023) Fluorescent Tools for the Imaging of Dopamine D2‐Like Receptors. ChemBioChem.

Rosier, Niklas , Moennich, Denise, Nagl, Martin, Schihada, Hannes, Sirbu, Alexei, Konar, Nergis, Reyes-Resina, Irene, Navarro, Gemma, Franco, Rafael, Kolb, Peter, Annibale, Paolo and Pockes, Steffen (2023) Shedding Light on the D1‐Like Receptors: A Fluorescence‐Based Toolbox for Visualization of the D1 and D5 Receptors. ChemBioChem.

Forster, Lisa and Pockes, Steffen (2022) Investigating the ligand agonism and antagonism at the D2long receptor by dynamic mass redistribution. Scientific Reports 12 (1).

Bresinsky, Merlin, Strasser, Jessica M., Hubmann, Alexander, Vallaster, Bernadette, McCue, William M., Fuller, Jessica, Singh, Gurpreet, Nelson, Kathryn M., Cuellar, Matthew E., Finzel, Barry C., Ashe, Karen H., Walters, Michael A. and Pockes, Steffen (2022) Characterization of caspase‐2 inhibitors based on specific sites of caspase‐2‐mediated proteolysis. Archiv der Pharmazie 355 (9), p. 2200095.

Pockes, Steffen and Tropmann, Katharina (2021) Histamine H2 receptor radioligands: triumphs and challenges. Future Medicinal Chemistry 13 (12), pp. 1073-1081.

Rosier, Niklas, Grätz, Lukas, Schihada, Hannes, Möller, Jan, Işbilir, Ali, Humphrys, Laura J., Nagl, Martin, Seibel, Ulla, Lohse, Martin J. and Pockes, Steffen (2021) A Versatile Sub-Nanomolar Fluorescent Ligand Enables NanoBRET Binding Studies and Single-Molecule Microscopy at the Histamine H3 Receptor. Journal of Medicinal Chemistry 64 (15), pp. 11695-11708. Fulltext not available.

Tropmann, Katharina, Bresinsky, Merlin, Forster, Lisa, Mönnich, Denise, Buschauer, Armin , Wittmann, Hans-Joachim, Hübner, Harald, Gmeiner, Peter, Pockes, Steffen and Strasser, Andrea (2021) Abolishing Dopamine D2long/D3 Receptor Affinity of Subtype-Selective Carbamoylguanidine-Type Histamine H2 Receptor Agonists. Journal of Medicinal Chemistry 64 (12), pp. 8684-8709. Fulltext not available.

Gergs, Ulrich, Büxel, Maren L., Bresinsky, Merlin, Kirchhefer, Uwe, Fehse, Charlotte, Höring, Carina, Hofmann, Britt, Marušáková, Margaréta, Čináková, Aneta, Schwarz, Rebecca, Pockes, Steffen and Neumann, Joachim (2021) Cardiac Effects of Novel Histamine H2 Receptor Agonists. Journal of Pharmacology and Experimental Therapeutics 379 (3), pp. 223-234. Fulltext not available.

Biselli, Sabrina, Bresinsky, Merlin, Tropmann, Katharina , Forster, Lisa, Honisch, Claudia, Buschauer, Armin , Bernhardt, Günther and Pockes, Steffen (2021) Pharmacological characterization of a new series of carbamoylguanidines reveals potent agonism at the H2R and D3R. European Journal of Medicinal Chemistry 214, p. 113190. Fulltext not available.

Szczepańska, Katarzyna, Pockes, Steffen , Podlewska, Sabina, Höring, Carina , Mika, Kamil, Latacz, Gniewomir, Bednarski, Marek, Siwek, Agata, Karcz, Tadeusz, Nagl, Martin, Bresinsky, Merlin, Mönnich, Denise, Seibel, Ulla, Kuder, Kamil J., Kotańska, Magdalena, Stark, Holger, Elz, Sigurd and Kieć-Kononowicz, Katarzyna (2021) Structural modifications in the distal, regulatory region of histamine H3 receptor antagonists leading to the identification of a potent anti-obesity agent. European Journal of Medicinal Chemistry 213, p. 113041. Fulltext not available.

Höring, Carina , Seibel, Ulla , Tropmann, Katharina, Grätz, Lukas , Mönnich, Denise , Pitzl, Sebastian, Bernhardt, Günther , Pockes, Steffen and Strasser, Andrea (2020) A Dynamic, Split-Luciferase-Based Mini-G Protein Sensor to Functionally Characterize Ligands at All Four Histamine Receptor Subtypes. International Journal of Molecular Sciences 21 (22), p. 8440.

Grätz, Lukas, Tropmann, Katharina, Bresinsky, Merlin, Müller, Christoph, Bernhardt, Günther and Pockes, Steffen (2020) NanoBRET binding assay for histamine H2 receptor ligands using live recombinant HEK293T cells. Scientific Reports 10, p. 13288.

Forster, Lisa , Grätz, Lukas, Mönnich, Denise, Bernhardt, Günther and Pockes, Steffen (2020) A Split Luciferase Complementation Assay for the Quantification of β-Arrestin2 Recruitment to Dopamine D2-Like Receptors. International Journal of Molecular Sciences 21 (17), p. 6103.

Schihada, Hannes , Ma, Xiaoyuan, Zabel, Ulrike, Vischer, Henry F., Schulte, Gunnar , Leurs, Rob, Pockes, Steffen and Lohse, Martin J. (2020) Development of a Conformational Histamine H3 Receptor Biosensor for the Synchronous Screening of Agonists and Inverse Agonists. ACS Sensors 5 (6), pp. 1734-1742. Fulltext not available.

Tropmann, Katharina, Höring, Carina , Plank, Nicole and Pockes, Steffen (2020) Discovery of a G Protein-Biased Radioligand for the Histamine H2 Receptor with Reversible Binding Properties. Journal of Medicinal Chemistry 63 (21), pp. 13090-13102. Fulltext not available.

Pockes, Steffen, Wifling, David , Buschauer, Armin and Elz, Sigurd (2019) Structure‐Activity Relationship of Hetarylpropylguanidines Aiming at the Development of Selective Histamine Receptor Ligands †. ChemistryOpen 8 (3), pp. 285-297.

Rustler, Karin , Pockes, Steffen and König, Burkhard (2019) Light-Switchable Antagonists for the Histamine H1 Receptor at the Isolated Guinea Pig Ileum. ChemMedChem 14 (6), pp. 636-644. Fulltext not available.

Rustler, Karin , Pockes, Steffen and König, Burkhard (2019) Cover Feature: Light‐Switchable Antagonists for the Histamine H 1 Receptor at the Isolated Guinea Pig Ileum (ChemMedChem 6/2019). ChemMedChem 14 (6), p. 614. Fulltext not available.

Soliman, Beatrice, Wang, Ning, Zagotto, Giuseppe and Pockes, Steffen (2019) Synthesis and biological evaluation of heteroalicyclic cyanoguanidines at histamine receptors. Archiv der Pharmazie 352 (9), p. 1900107. Fulltext not available.

Pockes, Steffen , Wifling, David , Keller, Max, Buschauer, Armin and Elz, Sigurd (2018) Highly Potent, Stable, and Selective Dimeric Hetarylpropylguanidine-Type Histamine H2 Receptor Agonists. ACS Omega 2018 (3), pp. 2865-2882.

Pockes, Steffen (2018) Synthese und pharmakologische Charakterisierung von Heteroarylpropylguanidin-Derivaten an Histamin-Rezeptorsubtypen: Struktur-Wirkungsbeziehungen mono- und bivalenter Liganden. PhD, Universität Regensburg.

Sadek, Bassem, Khan, Nadia, Darras, Fouad H., Pockes, Steffen and Decker, Michael (2016) The dual-acting AChE inhibitor and H3 receptor antagonist UW-MD-72 reverses amnesia induced by scopolamine or dizocilpine in passive avoidance paradigm in rats. Physiology & Behavior 165, pp. 383-391. Fulltext not available.

Darras, Fouad, Pockes, Steffen , Huang, Guozheng, Wehle, Sarah, Strasser, Andrea, Wittmann, Hans-Joachim, Nimczick, Martin, Sotriffer, Christoph and Decker, Michael (2014) Synthesis, biological evaluation, and computational studies of tri- and tetracyclic nitrogen-bridgehead compounds as potent dual-acting AChE inhibitors and hH3 receptor antagonists. ACS Chemical Neuroscience 5 (3), pp. 225-242. Fulltext not available.