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, Petroff, David, Wrigge, Hermann, Dumps, Christian, Heller, Axel R. and Simon, Philipp
(2025)
Surgical Antibiotic Prophylaxis Dosing in Adult Patients with Obesity: A Comprehensive Review of Pharmacokinetic and Pharmacodynamic Data.
Anesthesiology 142 (5), pp. 929-948.
Fulltext not available.
Stommel, Alexandra-Maria
, Matzneller, Peter, al Jalali, Valentin, Wulkersdorfer, Beatrix, Lackner, Edith, Mueller, Matthias, Dorn, Christoph
, Holzer, Michael and Zeitlinger, Markus
(2025)
Impact of Hypothermic Temperature Control on Plasma and Soft Tissue Pharmacokinetics of Penicillin/Beta-Lactamase Inhibitor Combinations in Patients Resuscitated After Cardiac Arrest.
Clinical Pharmacokinetics.
Ahmed, Hifza, Dorn, Christoph
and Zeitlinger, Markus
(2025)
Interspecies differences in Plasma Protein Binding of Beta-Lactam Antibiotics.
International Journal of Antimicrobial Agents, p. 107476.
Bindellini, Davide, Simon, Philipp, Busse, David, Michelet, Robin, Petroff, David, Aulin, Linda B. S., Dorn, Christoph
, Zeitlinger, Markus, Huisinga, Wilhelm, Wrigge, Hermann and Kloft, Charlotte
(2025)
Evaluation of the need for dosing adaptations in obese patients for surgical antibiotic prophylaxis: a model-based analysis of cefazolin pharmacokinetics.
British Journal of Anaesthesia.
, Lier, Constantin, Adamzik, Michael, Nowak, Hartmuth and Rahmel, Tim
(2024)
Concentrations of ceftazidime and avibactam in bile fluid—a prospective phase IIb study.
Journal of Antimicrobial Chemotherapy 79 (12), pp. 3297-3302.
Fulltext not available.
Sanz-Codina, Maria, van Os, Wisse, Pham, Anh Duc, Jorda, Anselm, Wölf-Duchek, Michael, Bergmann, Felix, Lackner, Edith, Lier, Constantin, Coen van Hasselt, J. G., Minichmayr, Iris K., Dorn, Christoph
, Zeitlinger, Markus and al Jalali, Valentin
(2024)
Target-site cefiderocol pharmacokinetics in soft tissues of healthy volunteers.
Journal of Antimicrobial Chemotherapy 79 (12), pp. 3281-3288.
Hosmann, Arthur, Moser, Miriam M, van Os, Wisse, Gramms, Leon, al Jalali, Valentin, Sanz Codina, Maria, Plöchl, Walter, Lier, Constantin, Kees, Frieder
, Dorn, Christoph
, Rössler, Karl, Reinprecht, Andrea and Zeitlinger, Markus
(2024)
Linezolid brain penetration in neurointensive care patients.
Journal of Antimicrobial Chemotherapy, dkae025.
Wulkersdorfer, Beatrix, Bergmann, Felix, Amann, Lisa, Fochtmann-Frana, Alexandra, Al Jalali, Valentin, Kurdina, Elizaveta, Lackner, Edith, Wicha, Sebastian G, Dorn, Christoph
, Schäfer, Bruno, Ihra, Gerald, Rath, Thomas, Radtke, Christine and Zeitlinger, Markus
(2023)
Effect of albumin substitution on pharmacokinetics of piperacillin/tazobactam in patients with severe burn injury admitted to the ICU.
Journal of Antimicrobial Chemotherapy.
and Zeitlinger, Markus
(2022)
Comparison of ultrafiltration and microdialysis for ceftriaxone protein-binding determination.
Journal of Antimicrobial Chemotherapy.
Fulltext not available.
, Wulkersdorfer, Beatrix, Schoergenhofer, Christian, Matzneller, Peter, Jalali, Valentin A. L., Bauer, Martin
, Wölfl‐Duchek, Michael, Lackner, Edith, Dorn, Christoph, Jilma, Bernd and Zeitlinger, Markus
(2022)
Effect of the human endotoxin challenge on tedizolid tissue penetration.
British Journal of Clinical Pharmacology, (accept.art.).
Fulltext not available.
Dorn, Christoph
, Petroff, David, Kratzer, Alexander, Kees, Frieder, Kloft, Charlotte, Zeitlinger, Markus
, Wrigge, Hermann and Simon, Philipp
(2022)
Tigecycline Soft Tissue Penetration in Obese and Non-obese Surgical Patients Determined by Using In Vivo Microdialysis.
European Journal of Drug Metabolism and Pharmacokinetics 47, pp. 749-755.
, Wulkersdorfer, Beatrix, Schörgenhofer, Christian, Matzneller, Peter
, Al Jalali, Valentin, Bauer, Martin
, Wölf-Duchek, Michael, Lackner, Edith, Dorn, Christoph, Jilma, Bernd
and Zeitlinger, Markus
(2022)
Influence of tedizolid on the cytokine response to the endotoxin challenge in healthy volunteers: a cross-over trial.
Journal of Antimicrobial Chemotherapy.
Fulltext not available.
Busse, David, Simon, Philipp, Schmitt, Lisa, Petroff, David, Dorn, Christoph
, Dietrich, Arne, Zeitlinger, Markus, Huisinga, Wilhelm, Michelet, Robin, Wrigge, Hermann and Kloft, Charlotte
(2021)
Comparative Plasma and Interstitial Tissue Fluid Pharmacokinetics of Meropenem Demonstrate the Need for Increasing Dose and Infusion Duration in Obese and Non-obese Patients.
Clinical Pharmacokinetics.
Busse, David
, Simon, Philipp
, Petroff, David, Dorn, Christoph, Schmitt, Lisa, Bindellini, Davide, Kratzer, Alexander, Dietrich, Arne, Zeitlinger, Markus, Huisinga, Wilhelm
, Michelet, Robin
, Wrigge, Hermann and Kloft, Charlotte
(2021)
Similar Piperacillin/Tazobactam Target Attainment in Obese versus Nonobese Patients despite Differences in Interstitial Tissue Fluid Pharmacokinetics.
Pharmaceutics 13 (9), p. 1380.
, Petroff, David, Stoelzel, Melanie, Kees, Martin G.
, Kratzer, Alexander, Dietrich, Arne, Kloft, Charlotte, Zeitlinger, Markus, Kees, Frieder
, Wrigge, Hermann and Simon, Philipp
(2021)
Perioperative administration of cefazolin and metronidazole in obese and non-obese patients: a pharmacokinetic study in plasma and interstitial fluid.
Journal of Antimicrobial Chemotherapy.
Fulltext not available.
, Wölfl-Duchek, M., Taubert, M.
, Matzneller, P.
, Lackner, E., Dorn, Christoph
, Kratzer, A., Wulkersdorfer, B., Österreicher, Z and Zeitlinger, Markus
(2021)
Plasma and soft tissue pharmacokinetics of ceftolozane/tazobactam in healthy volunteers after single and multiple intravenous infusion: a microdialysis study.
Journal of Antimicrobial Chemotherapy.
Fulltext not available.
and Zeitlinger, Markus
(2021)
Protein binding of clindamycin in vivo by means of intravascular microdialysis in healthy volunteers.
Journal of Antimicrobial Chemotherapy.
Fulltext not available.
Dorn, Christoph
, Schießer, Selina, Wulkersdorfer, Beatrix, Hitzenbichler, Florian, Kees, Martin G.
and Zeitlinger, Markus
(2020)
Determination of free clindamycin, flucloxacillin or tedizolid in plasma: Keep attention to physiological conditions when using ultrafiltration.
Biomedical Chromatography 34, e4820.
Ullah, Sami, Beer, Ronny, Fuhr, Uwe, Taubert, Max
, Zeitlinger, Markus, Kratzer, Alexander, Dorn, Christoph, Arshad, Usman, Kofler, Mario and Helbok, Raimund
(2020)
Brain Exposure to Piperacillin in Acute Hemorrhagic Stroke Patients Assessed by Cerebral Microdialysis and Population Pharmacokinetics.
Neurocritical Care.
Simon, Philipp
, Busse, David
, Petroff, David
, Dorn, Christoph
, Ehmann, Lisa, Hochstädt, Sophie, Girrbach, Felix, Dietrich, Arne, Zeitlinger, Markus, Kees, Frieder, Kloft, Charlotte and Wrigge, Hermann
(2020)
Linezolid Concentrations in Plasma and Subcutaneous Tissue are Reduced in Obese Patients, Resulting in a Higher Risk of Underdosing in Critically Ill Patients: A Controlled Clinical Pharmacokinetic Study.
Journal of Clinical Medicine 9 (4), p. 1067.
Simon, Philipp, Petroff, David, Busse, David
, Heyne, Jana, Girrbach, Felix, Dietrich, Arne, Kratzer, Alexander Ludwig, Zeitlinger, Markus, Kloft, Charlotte, Kees, Frieder, Wrigge, Hermann and Dorn, Christoph
(2020)
Meropenem Plasma and Interstitial Soft Tissue Concentrations in Obese and Nonobese Patients—A Controlled Clinical Trial.
Antibiotics 9 (12), p. 931.
, Dietrich, Arne, Kloft, Charlotte, Zeitlinger, Markus
, Kees, Martin, Kees, Frieder, Wrigge, Hermann and Simon, Philipp
(2019)
Plasma and tissue pharmacokinetics of fosfomycin in morbidly obese and non-obese surgical patients: a controlled clinical trial.
Journal of Antimicrobial Chemotherapy.
Fulltext not available.
and Zeitlinger, Markus
(2019)
Low pH reduces the activity of ceftolozane/tazobactam in human urine, but confirms current breakpoints for urinary tract infections.
Journal of Antimicrobial Chemotherapy.
Fulltext not available.
and Rahmel, Tim
(2019)
Repeated determination of moxifloxacin concentrations in interstitial space fluid of muscle and subcutis in septic patients.
Journal of Antimicrobial Chemotherapy.
Fulltext not available.
, Schlossmann, Jens
, Kees, Frieder
and Dorn, Christoph
(2018)
Determination of Total and Free Ceftolozane and Tazobactam in Human Plasma and Interstitial Fluid by HPLC-UV.
Journal of Pharmaceutical and Biomedical Analysis.
Fulltext not available.
Dorn, Christoph
, Nowak, Hartmuth, Weidemann, Caroline, Martini, Stefan, Zeitlinger, Markus, Adamzik, Michael and Kees, Frieder K.
(2017)
Decreased protein binding of moxifloxacin in patients with sepsis?
GMS Infectious Diseases 2017 (5), Doc03.
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