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Anzahl der Einträge: 48.

2023

Klemm, Sophie, Evert, Katja , Utpatel, Kirsten , Muggli, Alexandra, Simile, Maria M., Chen, Xin, Evert, Matthias, Calvisi, Diego F. und Scheiter, Alexander (2023) Identification of DUSP4/6 overexpression as a potential rheostat to NRAS-induced hepatocarcinogenesis. BMC Cancer 23.

2022

Cigliano, Antonio, Zhang, Shanshan, Ribback, Silvia, Steinmann, Sara, Sini, Marcella, Ament, Cindy E., Utpatel, Kirsten, Song, Xinhua, Wang, Jingxiao , Pilo, Maria G., Berger, Fabian, Wang, Haichuan , Tao, Junyan, Li, Xiaolei, Pes, Giovanni M. , Mancarella, Serena, Giannelli, Gianluigi, Dombrowski, Frank, Evert, Matthias, Calvisi, Diego F., Chen, Xin und Evert, Katja (2022) The Hippo pathway effector TAZ induces intrahepatic cholangiocarcinoma in mice and is ubiquitously activated in the human disease. Journal of Experimental & Clinical Cancer Research 41, art.no.192.

Mancarella, Serena, Gigante, Isabella, Serino, Grazia, Pizzuto, Elena, Dituri, Francesco, Valentini, Maria F., Wang, Jingxiao, Chen, Xin, Armentano, Raffaele, Calvisi, Diego F. und Giannelli, Gianluigi (2022) Crenigacestat blocking notch pathway reduces liver fibrosis in the surrounding ecosystem of intrahepatic CCA viaTGF-β inhibition. Journal of Experimental & Clinical Cancer Research 41 (1). Volltext nicht vorhanden.

Zhou, Yi, Tao, Junyan, Calvisi, Diego F. und Chen, Xin (2022) Role of Lipogenesis Rewiring in Hepatocellular Carcinoma. Seminars in Liver Disease 42 (01), 077-086. Volltext nicht vorhanden.

Wang, Haichuan, Zhang, Shanshan, Zhang, Yi, Jia, Jiaoyuan, Wang, Jingxiao, Liu, Xianqiong, Zhang, Jie, Song, Xinhua, Ribback, Silvia, Cigliano, Antonio, Evert, Matthias, Liang, Bingyong, Wu, Hong, Calvisi, Diego F., Zeng, Yong und Chen, Xin (2022) TAZ is indispensable for c-MYC-induced hepatocarcinogenesis. Journal of Hepatology 76 (1), S. 123-134. Volltext nicht vorhanden.

Zhang, Yi, Xu, Hongwei, Cui, Guofei, Liang, Binyong, Chen, Xiangzheng, Ko, Sungjin, Affo, Silvia, Song, Xinhua, Liao, Yi, Feng, Jianguo, Wang, Pan , Wang, Haichuan , Xu, Meng, Wang, Jingxiao , Pes, Giovanni M. , Ribback, Silvia, Zeng, Yong, Singhi, Aatur, Schwabe, Robert F., Monga, Satdarshan P., Evert, Matthias, Tang, Liling, Calvisi, Diego F. und Chen, Xin (2022) β-Catenin Sustains and Is Required for YES-associated Protein Oncogenic Activity in Cholangiocarcinoma. Gastroenterology 163 (2), S. 481-494. Volltext nicht vorhanden.

2021

Scheiter, Alexander, Evert, Katja , Reibenspies, Lucas, Cigliano, Antonio , Annweiler, Katharina, Müller, Karolina , Pöhmerer, Laura-Maria-Giovanna, Xu, Hongwei, Cui, Guofei, Itzel, Timo, Materna-Reichelt, Silvia, Coluccio, Andrea, Honarnejad, Kamran, Teufel, Andreas, Brochhausen, Christoph , Dombrowski, Frank, Chen, Xin, Evert, Matthias, Calvisi, Diego F. und Utpatel, Kirsten (2021) RASSF1A independence and early galectin-1 upregulation in PIK3CA-induced hepatocarcinogenesis: new therapeutic venues. Molecular Oncology 16 (5), S. 1091-1118.

Xu, Hongwei, Chen, Kefei, Shang, Runze, Chen, Xinyan, Zhang, Yi, Song, Xinhua, Evert, Matthias, Zhong, Sheng, Li, Bo, Calvisi, Diego F. und Chen, Xin (2021) Alpelisib combination treatment as novel targeted therapy against hepatocellular carcinoma. Cell Death & Disease 12 (10). Volltext nicht vorhanden.

Cigliano, Antonio, Chen, Xin und Calvisi, Diego F. (2021) Current challenges to underpinning the genetic basis for cholangiocarcinoma. Expert Review of Gastroenterology & Hepatology 15 (5), S. 511-526. Volltext nicht vorhanden.

Wang, Haichuan , Wang, Jingxiao , Zhang, Shanshan, Jia, Jiaoyuan, Liu, Xianqiong, Zhang, Jie, Wang, Pan , Song, Xinhua, Che, Li, Liu, Ke, Ribback, Silvia, Cigliano, Antonio , Evert, Matthias, Wu, Hong, Calvisi, Diego F., Zeng, Yong und Chen, Xin (2021) Distinct and Overlapping Roles of Hippo Effectors YAP and TAZ During Human and Mouse Hepatocarcinogenesis. Cellular and Molecular Gastroenterology and Hepatology 11 (4), S. 1095-1117. Volltext nicht vorhanden.

Wang, Haichuan , Wang, Pan , Xu, Meng, Song, Xinhua, Wu, Hong, Evert, Matthias, Calvisi, Diego F., Zeng, Yong und Chen, Xin (2021) Distinct functions of transforming growth factor-β signaling in c-MYC driven hepatocellular carcinoma initiation and progression. Cell Death & Disease 12 (2). Volltext nicht vorhanden.

Pocaterra, Arianna, Scattolin, Gloria , Romani, Patrizia, Ament, Cindy, Ribback, Silvia, Chen, Xin, Evert, Matthias, Calvisi, Diego F. und Dupont, Sirio (2021) Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development. Communications Biology 4 (1). Volltext nicht vorhanden.

Song, Xinhua, Xu, Hongwei, Wang, Pan , Wang, Jingxiao , Affo, Silvia , Wang, Haichuan , Xu, Meng, Liang, Binyong, Che, Li, Qiu, Wei , Schwabe, Robert F., Chang, Tammy T., Vogl, Marion, Pes, Giovanni M. , Ribback, Silvia, Evert, Matthias, Chen, Xin und Calvisi, Diego F. (2021) Focal adhesion kinase (FAK) promotes cholangiocarcinoma development and progression via YAP activation. Journal of Hepatology 75 (4), S. 888-899. Volltext nicht vorhanden.

Wang, Haichuan , Chen, Xin und Calvisi, Diego F. (2021) Hepatocellular carcinoma (HCC): the most promising therapeutic targets in the preclinical arena based on tumor biology characteristics. Expert Opinion on Therapeutic Targets 25 (8), S. 645-658. Volltext nicht vorhanden.

Zhang, Yi, Liang, Binyong, Song, Xinhua, Wang, Haichuan , Evert, Matthias, Zhou, Yi, Calvisi, Diego F., Tang, Liling und Chen, Xin (2021) Loss of Apc Cooperates with Activated Oncogenes to Induce Liver Tumor Formation in Mice. The American Journal of Pathology 191 (5), S. 930-946. Volltext nicht vorhanden.

Zhang, Yi, Solinas, Antonio, Cairo, Stefano, Evert, Matthias, Chen, Xin und Calvisi, Diego F. (2021) Molecular Mechanisms of Hepatoblastoma. Seminars in Liver Disease 41 (01), 028-041. Volltext nicht vorhanden.

Wang, Haichuan , Calvisi, Diego F. und Chen, Xin (2021) Organoids for the Study of Liver Cancer. Seminars in Liver Disease 41 (01), 019-027. Volltext nicht vorhanden.

Wang, Haichuan , Song, Xinhua, Liao, Haotian, Wang, Pan , Zhang, Yi, Che, Li, Zhang, Jie, Zhou, Yi, Cigliano, Antonio, Ament, Cindy, Superville, Daphne, Ribback, Silvia, Reeves, Melissa, Pes, Giovanni M. , Liang, Binyong, Wu, Hong, Evert, Matthias, Calvisi, Diego F., Zeng, Yong und Chen, Xin (2021) Overexpression of Mothers Against Decapentaplegic Homolog 7 Activates the Yes‐Associated Protein/NOTCH Cascade and Promotes Liver Carcinogenesis in Mice and Humans. Hepatology 74 (1), S. 248-263. Volltext nicht vorhanden.

Affo, Silvia , Nair, Ajay , Brundu, Francesco , Ravichandra, Aashreya , Bhattacharjee, Sonakshi, Matsuda, Michitaka, Chin, LiKang, Filliol, Aveline , Wen, Wen , Song, Xinhua, Decker, Aubrianna, Worley, Jeremy, Caviglia, Jorge Matias, Yu, Lexing, Yin, Deqi, Saito, Yoshinobu , Savage, Thomas, Wells, Rebecca G., Mack, Matthias, Zender, Lars, Arpaia, Nicholas, Remotti, Helen E., Rabadan, Raul, Sims, Peter, Leblond, Anne-Laure, Weber, Achim, Riener, Marc-Oliver, Stockwell, Brent R., Gaublomme, Jellert, Llovet, Josep M. , Kalluri, Raghu , Michalopoulos, George K., Seki, Ekihiro , Sia, Daniela , Chen, Xin, Califano, Andrea und Schwabe, Robert F. (2021) Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations. Cancer Cell 39 (6), 866-882.e11. Volltext nicht vorhanden.

Lu, Xinjun, Paliogiannis, Panagiotis , Calvisi, Diego F. und Chen, Xin (2021) Role of the Mammalian Target of Rapamycin Pathway in Liver Cancer: From Molecular Genetics to Targeted Therapies. Hepatology 73 (S1), S. 49-61. Volltext nicht vorhanden.

Liang, Binyong, Zhou, Yi, Qian, Manning, Xu, Meng, Wang, Jingxiao , Zhang, Yi, Song, Xinhua, Wang, Haichuan , Lin, Shumei, Ren, Chuanli, Monga, Satdarshan P., Wang, Bruce , Evert, Matthias, Chen, Yifa, Chen, Xiaoping, Huang, Zhiyong, Calvisi, Diego F. und Chen, Xin (2021) TBX3 functions as a tumor suppressor downstream of activated CTNNB1 mutants during hepatocarcinogenesis. Journal of Hepatology 75 (1), S. 120-131. Volltext nicht vorhanden.

Lu, Xinjun, Peng, Baogang, Chen, Ge, Pes, Mario G. , Ribback, Silvia, Ament, Cindy , Xu, Hongwei, Pal, Rajesh , Rodrigues, Pedro M. , Banales, Jesus M., Evert, Matthias, Calvisi, Diego F., Chen, Xin, Fan, Biao und Wang, Jingxiao (2021) YAP Accelerates Notch-Driven Cholangiocarcinogenesis via mTORC1 in Mice. The American Journal of Pathology 191 (9), S. 1651-1667. Volltext nicht vorhanden.

2020

Chen, Xinyan, Kiss, Andras, Schaff, Zsuzsa, Evert, Katja, Zhang, Yi, Zhong, Sheng, Wang, Jingxiao, Evert, Matthias, Calvisi, Diego F. und Chen, Xin (2020) CDK9 is dispensable for YAP‐driven hepatoblastoma development. Pediatric Blood & Cancer 67 (5). Volltext nicht vorhanden.

Shang, Runze, Song, Xinhua, Wang, Pan, Zhou, Yi, Lu, Xinjun, Wang, Jingxiao, Xu, Meng, Chen, Xinyan, Utpatel, Kirsten, Che, Li, Liang, Binyong, Cigliano, Antonio, Evert, Matthias, Calvisi, Diego F. und Chen, Xin (2020) Cabozantinib-based combination therapy for the treatment of hepatocellular carcinoma. Gut 70 (9), S. 1746-1757. Volltext nicht vorhanden.

Mancarella, Serena, Serino, Grazia, Dituri, Francesco, Cigliano, Antonio , Ribback, Silvia, Wang, Jingxiao, Chen, Xin, Calvisi, Diego F. und Giannelli, Gianluigi (2020) Crenigacestat, a selective NOTCH1 inhibitor, reduces intrahepatic cholangiocarcinoma progression by blocking VEGFA/DLL4/MMP13 axis. Cell Death & Differentiation 27 (8), S. 2330-2343. Volltext nicht vorhanden.

Chen, Bin , Garmire, Lana, Calvisi, Diego F., Chua, Mei-Sze, Kelley, Robin K. und Chen, Xin (2020) Harnessing big ‘omics’ data and AI for drug discovery in hepatocellular carcinoma. Nature Reviews Gastroenterology & Hepatology 17 (4), S. 238-251. Volltext nicht vorhanden.

Zhou, Yi, Xu, Meng, Liu, Pin, Liang, Binyong, Qian, Manning, Wang, Haichuan , Song, Xinhua, Nyshadham, Pranavanand, Che, Li, Calvisi, Diego F., Li, Feng, Lin, Shumei und Chen, Xin (2020) Mammalian Target of Rapamycin Complex 2 Signaling Is Required for Liver Regeneration in a Cholestatic Liver Injury Murine Model. The American Journal of Pathology 190 (7), S. 1414-1426. Volltext nicht vorhanden.

Wang, Pan , Song, Xinhua, Cao, Dan, Cui, Kairong, Wang, Jingxiao , Utpatel, Kirsten, Shang, Runze , Wang, Haichuan , Che, Li, Evert, Matthias, Zhao, Keji, Calvisi, Diego F. und Chen, Xin (2020) Oncogene-dependent function of BRG1 in hepatocarcinogenesis. Cell Death & Disease 11 (2). Volltext nicht vorhanden.

Jia, Jiaoyuan, Che, Li, Cigliano, Antonio , Wang, Xue, Peitta, Graziella, Tao, Junyan, Zhong, Sheng, Ribback, Silvia, Evert, Matthias, Chen, Xin und Calvisi, Diego F. (2020) Pivotal Role of Fatty Acid Synthase in c-MYC Driven Hepatocarcinogenesis. International Journal of Molecular Sciences 21 (22), S. 8467. Volltext nicht vorhanden.

Zhang, Shu, Zhang, Jie, Evert, Katja, Li, Xiaolei, Liu, Pin, Kiss, Andras, Schaff, Zsuzsa, Ament, Cindy , Zhang, Yi, Serra, Monica, Evert, Matthias, Chen, Nianyong, Xu, Feng, Chen, Xin, Tao, Junyan, Calvisi, Diego F. und Cigliano, Antonio (2020) The Hippo Effector Transcriptional Coactivator with PDZ-Binding Motif Cooperates with Oncogenic β-Catenin to Induce Hepatoblastoma Development in Mice and Humans. The American Journal of Pathology 190 (7), S. 1397-1413. Volltext nicht vorhanden.

Xu, Meng, Wang, Haichuan , Wang, Jingxiao , Burhan, Deviana , Shang, Runze , Wang, Pan , Zhou, Yi, Li, Rong, Liang, Bingyong, Evert, Katja, Utpatel, Kirsten, Xu, Zhong, Song, Xinhua, Che, Li, Calvisi, Diego F., Wang, Bruce , Chen, Xi, Zeng, Yong und Chen, Xin (2020) mTORC2 Signaling Is Necessary for Timely Liver Regeneration after Partial Hepatectomy. The American Journal of Pathology 190 (4), S. 817-829. Volltext nicht vorhanden.

2019

Che, Li, Paliogiannis, Panagiotis, Cigliano, Antonio , Pilo, Maria G., Chen, Xin und Calvisi, Diego F. (2019) Pathogenetic, Prognostic, and Therapeutic Role of Fatty Acid Synthase in Human Hepatocellular Carcinoma. Frontiers in Oncology 9 (1412), S. 1-10.

Qiao, Yu, Wang, Jingxiao, Karagoz, Eylul, Liang, Binyong, Song, Xinhua, Shang, Runze, Evert, Katja, Xu, Meng, Che, Li, Evert, Matthias, Calvisi, Diego F., Tao, Junyan, Wang, Bruce, Monga, Satdarshan P. und Chen, Xin (2019) Axis inhibition protein 1 (Axin1) Deletion–Induced Hepatocarcinogenesis Requires Intact β‐Catenin but Not Notch Cascade in Mice. Hepatology 70 (6), S. 2003-2017. Volltext nicht vorhanden.

Che, Li, Chi, Wenna, Qiao, Yu, Zhang, Jie, Song, Xinhua, Liu, Ye, Li, Lei, Jia, Jiaoyuan, Pilo, Maria G., Wang, Jingxiao, Cigliano, Antonio , Ma, Zhilong, Kuang, Wenhua, Tang, Zefang, Zhang, Zemin, Shui, Guanghou, Ribback, Silvia, Dombrowski, Frank, Evert, Matthias, Pascale, Rosa Maria, Cossu, Carla, Pes, Giovanni Mario , Osborne, Timothy F., Calvisi, Diego F., Chen, Xin und Chen, Ligong (2019) Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans. Gut 69 (1), S. 177-186. Volltext nicht vorhanden.

Brown, Peter , Tan, Aik-Choon, El-Esawi, Mohamed A., Liehr, Thomas, Blanck, Oliver, Gladue, Douglas P., Almeida, Gabriel M. F., Cernava, Tomislav , Sorzano, Carlos O., Yeung, Andy W. K. , Engel, Michael S., Chandrasekaran, Arun Richard, Muth, Thilo, Staege, Martin S., Daulatabad, Swapna V., Widera, Darius, Zhang, Junpeng , Meule, Adrian , Honjo, Ken, Pourret, Olivier , Yin, Cong-Cong, Zhang, Zhongheng , Cascella, Marco, Flegel, Willy A., Goodyear, Carl S., van Raaij, Mark J., Bukowy-Bieryllo, Zuzanna, Campana, Luca G., Kurniawan, Nicholas A., Lalaouna, David, Hüttner, Felix J., Ammerman, Brooke A., Ehret, Felix, Cobine, Paul A., Tan, Ene-Choo, Han, Hyemin, Xia, Wenfeng , McCrum, Christopher, Dings, Ruud P. M., Marinello, Francesco, Nilsson, Henrik , Nixon, Brett, Voskarides, Konstantinos, Yang, Long , Costa, Vincent D., Bengtsson-Palme, Johan, Bradshaw, William, Grimm, Dominik G. , Kumar, Nitin, Martis, Elvis, Prieto, Daniel, Sabnis, Sandeep C., Amer, Said E. D. R., Liew, Alan W. C., Perco, Paul, Rahimi, Farid , Riva, Giuseppe, Zhang, Chongxing , Devkota, Hari P. , Ogami, Koichi , Basharat, Zarrin, Fierz, Walter, Siebers, Robert, Tan, Kok-Hian, Boehme, Karen A., Brenneisen, Peter, Brown, James A. L. , Dalrymple, Brian P., Harvey, David J., Ng, Grace, Werten, Sebastiaan , Bleackley, Mark, Dai, Zhanwu, Dhariwal, Raman, Gelfer, Yael, Hartmann, Marcus D., Miotla, Pawel, Tamaian, Radu, Govender, Pragashnie, Gurney-Champion, Oliver J., Kauppila, Joonas H., Zhang, Xiaolei , Echeverría, Natalia, Subhash, Santhilal , Sallmon, Hannes, Tofani, Marco, Bae, Taeok, Bosch, Oliver, Cuív, Páraic O., Danchin, Antoine, Diouf, Barthelemy, Eerola, Tuomas, Evangelou, Evangelos, Filipp, Fabian V. , Klump, Hannes, Kurgan, Lukasz, Smith, Simon S., Terrier, Olivier, Tuttle, Neil , Ascher, David B., Janga, Sarath C., Schulte, Leon N. , Becker, Daniel, Browngardt, Christopher, Bush, Stephen J. , Gaullier, Guillaume , Ide, Kazuki, Meseko, Clement, Werner, Gijsbert D. A., Zaucha, Jan, Al-Farha, Abd A., Greenwald, Noah F., Popoola, Segun I. , Rahman, Md Shaifur, Xu, Jialin , Yang, Sunny Y. , Hiroi, Noboru, Alper, Ozgul M., Baker, Chris I., Bitzer, Michael, Chacko, George, Debrabant, Birgit, Dixon, Ray, Forano, Evelyne, Gilliham, Matthew, Kelly, Sarah, Klempnauer, Karl-Heinz, Lidbury, Brett A., Lin, Michael Z., Lynch, Iseult, Ma, Wujun, Maibach, Edward W., Mather, Diane E., Nandakumar, Kutty S., Ohgami, Robert S., Parchi, Piero, Tressoldi, Patrizio, Xue, Yu, Armitage, Charles , Barraud, Pierre, Chatzitheochari, Stella, Coelho, Luis P. , Diao, Jiajie , Doxey, Andrew C., Gobet, Angélique, Hu, Pingzhao , Kaiser, Stefan, Mitchell, Kate M., Salama, Mohamed F. , Shabalin, Ivan G. , Song, Haijun, Stevanovic, Dejan, Yadollahpour, Ali, Zeng, Erliang , Zinke, Katharina, Alimba, C. G., Beyene, Tariku J., Cao, Zehong, Chan, Sherwin S., Gatchell, Michael, Kleppe, Andreas , Piotrowski, Marcin , Torga, Gonzalo, Woldesemayat, Adugna A., Cosacak, Mehmet I., Haston, Scott, Ross, Stephanie A., Williams, Richard, Wong, Alvin, Abramowitz, Matthew K., Effiong, Andem, Lee, Senhong, Abid, Muhammad Bilal, Agarabi, Cyrus, Alaux, Cedric , Albrecht, Dirk R., Atkins, Gerald J., Beck, Charles R., Bonvin, A. M. J. J., Bourke, Emer, Brand, Thomas, Braun, Ralf J. , Bull, James A. , Cardoso, Pedro , Carter, Dee, Delahay, Robin M., Ducommun, Bernard, Duijf, Pascal H. G., Epp, Trevor, Eskelinen, Eeva-Liisa , Fallah, Mazyar, Farber, Debora B., Fernandez-Triana, Jose, Feyerabend, Frank, Florio, Tullio, Friebe, Michael, Furuta, Saori, Gabrielsen, Mads, Gruber, Jens, Grybos, Malgorzata, Han, Qian, Heinrich, Michael, Helanterä, Heikki, Huber, Michael, Jeltsch, Albert, Jiang, Fan, Josse, Claire, Jurman, Giuseppe, Kamiya, Haruyuki, de Keersmaecker, Kim, Kristiansson, Erik, de Leeuw, Frank-Erik, Li, Jiuyong, Liang, Shide, Lopez-Escamez, Jose A., Lopez-Ruiz, Francisco J., Marchbank, Kevin J., Marschalek, Rolf, Martín, Carmen S., Miele, Adriana E., Montagutelli, Xavier, Morcillo, Esteban, Nicoletti, Rosario, Niehof, Monika, O’Toole, Ronan , Ohtomo, Toshihiko, Oster, Henrik , Palma, Jose-Alberto, Paterson, Russell, Peifer, Mark, Portilla, Maribel, Portillo, M. C., Pritchard, Antonia L., Pusch, Stefan, Raghava, Gajendra P. S., Roberts, Nicola J., Ross, Kehinde, Schuele, Birgitt, Sergeant, Kjell, Shen, Jun, Stella, Alessandro , Sukocheva, Olga, Uversky, Vladimir N., Vanneste, Sven, Villet, Martin H., Viveiros, Miguel , Vorholt, Julia A., Weinstock, Christof, Yamato, Masayuki, Zabetakis, Ioannis , Zhao, Xin, Ziegler, Andreas, Aizat, Wan M., Atlas, Lauren, Bridges, Kristina M., Chakraborty, Sayan, Deschodt, Mieke, Domingues, Helena S. , Esfahlani, Shabnam S., Falk, Sebastian, Guisado, J. L. , Kane, Nolan C., Kueberuwa, Gray, Lau, Colleen L. , Liang, Dai, Liu, Enwu , Luu, Andreas M., Ma, Chuang, Ma, Lisong, Moyer, Robert, Norris, Adam D., Panthee, Suresh, Parsons, Jerod R., Peng, Yousong, Pinto, Inês Mendes, Reschke, Cristina R., Sillanpää, Elina, Stewart, Christopher J., Uhle, Florian, Yang, Hui , Zhou, Kai , Zhu, Shu, Ashry, Mohamed, Bergsland, Niels, Berthold, Maximilian , Chen, Chang-Er , Colella, Vito, Cuypers, Maarten, Eskew, Evan A., Fan, Xiao, Gajda, Maksymilian, Gonzálezlez-Prendes, Rayner, Goodin, Amie, Graham, Emily B., Groen, Ewout J. N., Gutiérrez-Sacristán, Alba, Habes, Mohamad, Heffler, Enrico, Higginbottom, Daniel B., Janzen, Thijs, Jayaraman, Jayakumar, Jibb, Lindsay A. , Jongen, Stefan, Kinyanjui, Timothy , Koleva-Kolarova, Rositsa G., Li, Zhixiu, Liu, Yu-Peng , Lund, Bjarte A., Lussier, Alexandre A., Ma, Liping, Mier, Pablo , Moore, Matthew D., Nagler, Katja, Orme, Mark W., Pearson, James A., Prajapati, Anilkumar S., Saito, Yu, Tröder, Simon E., Uchendu, Florence, Verloh, Niklas, Voutchkova, Denitza D., Abu-Zaid, Ahmed, Bakkach, Joaira, Baumert, Philipp , Dono, Marcos, Hanson, Jack, Herbelet, Sandrine, Hobbs, Emma, Kulkarni, Ameya, Kumar, Narendra, Liu, Siqi , Loft, Nikolai D., Reddan, Tristan, Senghore, Thomas , Vindin, Howard, Xu, Haotian , Bannon, Ross, Chen, Branson , Cheung, Johnny T. K., Cooper, Jeffrey, Esnakula, Ashwini K., Feghali, Karine A., Ghelardi, Emilia, Gnasso, Agostino, Horbar, Jeffrey, Lai, Hei M., Li, Jian, Ma, Lan, Ma, Ruiyan, Pan, Zihang, Peres, Marco A., Pranata, Raymond , Seow, Esmond, Sydes, Matthew, Testoni, Ines, Westermair, Anna L., Yang, Yongliang , Afnan, Masoud, Albiol, Joan, Albuquerque, Lucia G., Amiya, Eisuke, Amorim, Rogerio M., An, Qianli, Andersen, Stig U., Aplin, John D., Argyropoulos, Christos, Asmann, Yan W., Assaeed, Abdulaziz M., Atanasov, Atanas G., Atchison, David A., Avery, Simon V., Avillach, Paul, Baade, Peter D., Backman, Lars, Badie, Christophe, Baldi, Alfonso, Ball, Elizabeth, Bardot, Olivier, Barnett, Adrian G., Basner, Mathias, Batra, Jyotsna, Bazanova, O. M., Beale, Andrew, Beddoe, Travis, Bell, Melanie L., Berezikov, Eugene, Berners-Price, Sue, Bernhardt, Peter, Berry, Edward, Bessa, Theolis B., Billington, Craig, Birch, John, Blakely, Randy D., Blaskovich, Mark A. T., Blum, Robert, Boelaert, Marleen, Bogdanos, Dimitrios, Bosch, Carles, Bourgoin, Thierry, Bouvard, Daniel, Boykin, Laura M. , Bradley, Graeme, Braun, Daniel , Brownlie, Jeremy, Brühl, Albert, Burt, Austin , Butler, Lisa M., Byrareddy, Siddappa N., Byrne, Hugh J. , Cabantous, Stephanie , Calatayud, Sara, Candal, Eva, Carlson, Kimberly, Casillas, Sònia , Castelvetro, Valter, Caswell, Patrick T., Cavalli, Giacomo, Cerovsky, Vaclav, Chagoyen, Monica, Chen, Chang-Shi , Chen, Dong F. , Chen, Hao , Chen, Hui , Chen, Jui-Tung , Chen, Yinglong , Cheng, Changxiu, Cheng, Jianlin, Chinapaw, Mai, Chinopoulos, Christos, Cho, William C. S., Chong, Lillian, Chowdhury, Debashish, Chwalibog, Andre, Ciresi, A., Cockcroft, Shamshad, Conesa, Ana, Cook, Penny A., Cooper, David N., Coqueret, Olivier, Corea, Enoka M., Costa, Elisio, Coupland, Carol, Crawford, Stephanie Y., Cruz, Aparecido D., Cui, Huijuan, Cui, Qiang, Culver, David C., D’Angiulli, Amedeo, Dahms, Tanya E. S., Daigle, France, Dalgleish, Raymond, Danielsen, Håvard E., Darras, Sébastien, Davidson, Sean M., Day, David A., Degirmenci, Volkan, Demaison, Luc, Devriendt, Koenraad, Ding, Jiandong, Dogan, Yunus, Dong, X. 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A., Williams, Brendan A., Workman, Alan D., Xiang, Tingxiu, Xie, Li-Xin, Xu, Jun , Xu, Taosheng , Yang, Chongjun , Yoon, Jihoon G., Yuan, Christina M., Zaritsky, Arno, Zhang, Yao , Zhao, Haochen, Zuckerman, Hannah, Lyu, Ran, Pullan, Wayne und Zhou, Yaoqi (2019) Large expert-curated database for benchmarking document similarity detection in biomedical literature search. Database 2019. Volltext nicht vorhanden.

Wang, Jingxiao , Wang, Haichuan , Peters, Michele, Ding, Ning, Ribback, Silvia, Utpatel, Kirsten, Cigliano, Antonio, Dombrowski, Frank, Xu, Meng, Chen, Xinyan, Song, Xinhua, Che, Li, Evert, Matthias, Cossu, Antonio, Gordan, John, Zeng, Yong, Chen, Xin und Calvisi, Diego F. (2019) Loss of Fbxw7 synergizes with activated Akt signaling to promote c-Myc dependent cholangiocarcinogenesis. Journal of Hepatology 71 (4), S. 742-752. Volltext nicht vorhanden.

Wang, Pan, Song, Xinhua, Utpatel, Kirsten, Shang, Runze, Yang, Yoon Mee, Xu, Meng, Zhang, Jie, Che, Li, Gordan, John, Cigliano, Antonio, Seki, Ekihiro , Evert, Matthias, Calvisi, Diego F., Hu, Xiaosong und Chen, Xin (2019) MEK inhibition suppresses K-Ras wild-type cholangiocarcinoma in vitro and in vivo via inhibiting cell proliferation and modulating tumor microenvironment. Cell Death & Disease 10 (2). Volltext nicht vorhanden.

Xu, Meng, Wang, Jingxiao, Xu, Zhong, Li, Rong, Wang, Pan, Shang, Runze, Cigliano, Antonio, Ribback, Silvia, Solinas, Antonio , Pes, Giovanni Mario , Evert, Katja, Wang, Haichuan, Song, Xinhua, Zhang, Shu, Che, Li, Pascale, Rosa Maria, Calvisi, Diego F., Liu, Qingguang und Chen, Xin (2019) SNAI1 promotes the cholangiocellular phenotype, but not epithelial-mesenchymal transition, in a murine hepatocellular carcinoma model. Cancer Research 79 (21), S. 5563-5574. Volltext nicht vorhanden.

Xu, Zhong, Xu, Meng, Liu, Pin, Zhang, Shu, Shang, Runze, Qiao, Yu, Che, Li, Ribback, Silvia, Cigliano, Antonio, Evert, Katja, Pascale, Rosa M., Dombrowski, Frank, Evert, Matthias, Chen, Xi, Calvisi, Diego F. und Chen, Xin (2019) The mTORC2‐Akt1 Cascade Is Crucial for c‐Myc to Promote Hepatocarcinogenesis in Mice and Humans. Hepatology 70 (5), S. 1600-1613. Volltext nicht vorhanden.

2018

Song, Xinhua, Liu, Xianqiong, Wang, Haichuan , Wang, Jingxiao , Qiao, Yu, Cigliano, Antonio, Utpatel, Kirsten, Ribback, Silvia, Pilo, Maria G., Serra, Marina, Gordan, John D., Che, Li, Zhang, Shanshan, Cossu, Antonio, Porcu, Alberto, Pascale, Rosa M., Dombrowski, Frank, Hu, Hongbo, Calvisi, Diego F., Evert, Matthias und Chen, Xin (2018) Combined CDK4/6 and Pan-mTOR Inhibition Is Synergistic Against Intrahepatic Cholangiocarcinoma. Clinical Cancer Research 25 (1), S. 403-413. Volltext nicht vorhanden.

Dong, Mingjie, Liu, Xianqiong, Evert, Katja, Utpatel, Kirsten, Peters, Michele, Zhang, Shanshan, Xu, Zhong, Che, Li, Cigliano, Antonio , Ribback, Silvia, Dombrowski, Frank, Cossu, Antonio, Gordan, John, Calvisi, Diego F., Evert, Matthias, Liu, Yan und Chen, Xin (2018) Efficacy of MEK inhibition in a K-Ras-driven cholangiocarcinoma preclinical model. Cell Death & Disease 9 (2). Volltext nicht vorhanden.

2017

Cigliano, Antonio , Wang, Chunmei, Pilo, Maria G., Szydlowska, Marta , Brozzetti, Stefania , Latte, Gavinella, Pes, Giovanni M., Pascale, Rosa M., Seddaiu, Maria A., Vidili, Gianpaolo, Ribback, Silvia, Dombrowski, Frank, Evert, Matthias, Chen, Xin und Calvisi, Diego F. (2017) Inhibition of HSF1 suppresses the growth of hepatocarcinoma cell lines <i>in vitro</i> and AKT-driven hepatocarcinogenesis in mice. Oncotarget 8 (33). Volltext nicht vorhanden.

Che, Li, Pilo, Maria G., Cigliano, Antonio , Latte, Gavinella , Simile, Maria M., Ribback, Silvia, Dombrowski, Frank, Evert, Matthias, Chen, Xin und Calvisi, Diego F. (2017) Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma. Cell Cycle 16 (6), S. 499-507. Volltext nicht vorhanden.

Zhang, Shanshan, Song, Xinhua, Cao, Dan, Xu, Zhong, Fan, Biao, Che, Li, Hu, Junjie, Chen, Bin, Dong, Mingjie, Pilo, Maria G., Cigliano, Antonio , Evert, Katja, Ribback, Silvia, Dombrowski, Frank, Pascale, Rosa M., Cossu, Antonio, Vidili, Gianpaolo, Porcu, Alberto, Simile, Maria M., Pes, Giovanni M., Giannelli, Gianluigi, Gordan, John, Wei, Lixin, Evert, Matthias, Cong, Wenming, Calvisi, Diego F. und Chen, Xin (2017) Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice. Journal of Hepatology 67 (6), S. 1194-1203. Volltext nicht vorhanden.

2016

Wang, Chunmei, Che, Li, Hu, Junjie, Zhang, Shanshan, Jiang, Lijie, Latte, Gavinella , Demartis, Maria I., Tao, Junyan, Gui, Bing, Pilo, Maria G., Ribback, Silvia, Dombrowski, Frank, Evert, Matthias, Calvisi, Diego F. und Chen, Xin (2016) Activated mutant forms of PIK3CA cooperate with RasV12 or c-Met to induce liver tumour formation in mice via AKT2/mTORC1 cascade. Liver International 36 (8), S. 1176-1186. Volltext nicht vorhanden.

Hu, Junjie, Che, Li, Li, Lei, Pilo, Maria G., Cigliano, Antonio , Ribback, Silvia, Li, Xiaolei, Latte, Gavinella , Mela, Marta, Evert, Matthias, Dombrowski, Frank, Zheng, Guohua, Chen, Xin und Calvisi, Diego F. (2016) Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice. Scientific Reports 6 (1). Volltext nicht vorhanden.

2008

Chen, Xin , Subleski, Jeffrey J., Kopf, Heather, Howard, O. M. Zack , Männel, Daniela N. und Oppenheim, Joost J. (2008) Cutting Edge: Expression of TNFR2 Defines a Maximally Suppressive Subset of Mouse CD4+CD25+FoxP3+ T Regulatory Cells: Applicability to Tumor-Infiltrating T Regulatory Cells. The Journal of Immunology 180 (10), S. 6467-6471. Volltext nicht vorhanden.

2007

Chen, Xin , Bäumel, Monika, Männel, Daniela N., Howard, O. M. Zack und Oppenheim, Joost J. (2007) Interaction of TNF with TNF Receptor Type 2 Promotes Expansion and Function of Mouse CD4+CD25+ T Regulatory Cells. The Journal of Immunology 179 (1), S. 154-161. Volltext nicht vorhanden.

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