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Dillinger, Andrea E., Kuespert, Sabrina, Seleem, Amin A.
, Neuendorf, Jakob, Schneider, Magdalena und Fuchshofer, Rudolf
(2023)
CCN2/CTGF tip the balance of growth factors towards TGF-β2 in primary open-angle glaucoma.
Frontiers in Molecular Biosciences 10.
, Girbig, Renée M., Schulte, Kim K., Theile, Janine
, Asaad, M. Ali, Fuchshofer, Rudolf
, Dick, H. Burkhard und Joachim, Stephanie C.
(2023)
Enhanced glaucomatous damage accompanied by glial response in a new multifactorial mouse model.
Frontiers in Immunology 13.
Volltext nicht vorhanden.
Dillinger, Andrea E., Weber, Gregor R., Mayer, Matthias, Schneider, Magdalena, Göppner, Corinna, Ohlmann, Andreas
, Shamonin, Mikhail, Monkman, Gareth J. und Fuchshofer, Rudolf
(2022)
CCN2/CTGF—A Modulator of the Optic Nerve Head Astrocyte.
Frontiers in Cell and Developmental Biology 10, S. 864433.
, van Batenburg-Sherwood, Joseph, Millar, J. Cameron, Kuehn, Markus H., Zode, Gulab, Acott, Ted S., Anderson, Michael G.
, Bhattacharya, Sanjoy K., Bertrand, Jacques A., Borras, Terete, Bovenkamp, Diane E.
, Cheng, Lin
, Danias, John, De Ieso, Michael Lucio, Du, Yiqin, Faralli, Jennifer A., Fuchshofer, Rudolf, Ganapathy, Preethi S.
, Gong, Haiyan
, Herberg, Samuel, Hernandez, Humberto, Humphries, Peter, John, Simon W. M., Kaufman, Paul L., Keller, Kate E.
, Kelley, Mary J., Kelly, Ruth A.
, Krizaj, David
, Kumar, Ajay
, Leonard, Brian C., Lieberman, Raquel L., Liton, Paloma, Liu, Yutao, Liu, Katy C., Lopez, Navita N., Mao, Weiming, Mavlyutov, Timur, McDonnell, Fiona, McLellan, Gillian J., Mzyk, Philip, Nartey, Andrews
, Pasquale, Louis R., Patel, Gaurang C., Pattabiraman, Padmanabhan P., Peters, Donna M., Raghunathan, Vijaykrishna, Rao, Ponugoti Vasantha, Rayana, Naga
, Raychaudhuri, Urmimala, Reina-Torres, Ester
, Ren, Ruiyi, Rhee, Douglas, Chowdhury, Uttio Roy, Samples, John R., Samples, E. Griffen, Sharif, Najam, Schuman, Joel S.
, Sheffield, Val C., Stevenson, Cooper H., Soundararajan, Avinash
, Subramanian, Preeti, Sugali, Chenna Kesavulu, Sun, Yang, Toris, Carol B., Torrejon, Karen Y., Vahabikashi, Amir, Vranka, Janice A., Wang, Ting, Willoughby, Colin E.
, Xin, Chen, Yun, Hongmin, Zhang, Hao F., Fautsch, Michael P., Tamm, Ernst R., Clark, Abbot F., Ethier, C. Ross
und Stamer, W. Daniel
(2022)
Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms.
Investigative Opthalmology & Visual Science 63 (2), S. 12.
Volltext nicht vorhanden.
Mietzner, Raphael
, Pawlak, Ramona
, Tamm, Ernst R., Goepferich, Achim
, Fuchshofer, Rudolf
und Breunig, Miriam
(2021)
Angiopoietin-1 Mimetic Nanoparticles for Restoring the Function of Endothelial Cells as Potential Therapeutic for Glaucoma.
Pharmaceuticals 15 (1), S. 18.
Fuchshofer, Rudolf
, Schneider, Magdalena, Dillinger, Andrea E., Ohlmann, Andreas
und Iozzo, Renato V.
(2021)
Decorin—An Antagonist of TGF-β in Astrocytes of the Optic Nerve.
International Journal of Molecular Sciences 22 (7660), S. 1-16.
Breunig, Miriam
, Sonntag, Tobias, Froemel, Franziska, Stamer, W. Daniel, Ohlmann, Andreas und Fuchshofer, Rudolf
(2021)
Distribution of Gold Nanoparticles in the Anterior Chamber of the Eye after Intracameral Injection for Glaucoma Therapy.
Pharmaceutics 2021 (13), S. 901.
(Eingereicht)
Fuchshofer, Rudolf
, Dillinger, Andrea E., Kuespert, Sabrina, Froemel, Franziska und Tamm, Ernst R.
(2021)
CCN2/CTGF promotor activity in the developing and adult mouse eye.
Cell and Tissue Research 384, S. 625-641.
, Weber, Gregor R., Dillinger, Andrea E., Kuespert, Sabrina, Iozzo, Renato V., Quigley, Harry A., Ohlmann, Andreas, Tamm, Ernst R.
und Fuchshofer, Rudolf
(2021)
A novel ocular function for decorin in the aqueous humor outflow.
Matrix Biology 97, S. 1-19.
Volltext nicht vorhanden.
, Mueller-Buehl, Ana M., Doerner, Johanna D., Fuchshofer, Rudolf
, Stute, Gesa, Dick, H. Burkhard und Joachim, Stephanie C.
(2021)
Activation of Apoptosis in a βB1-CTGF Transgenic Mouse Model.
International Journal of Molecular Sciences 22 (4), S. 1997.
Volltext nicht vorhanden.
Mietzner, Raphael
, Kade, Christian, Froemel, Franziska, Pauly, Diana, Stamer, W. Daniel, Ohlmann, Andreas, Wegener, Joachim, Fuchshofer, Rudolf und Breunig, Miriam
(2020)
Fasudil Loaded PLGA Microspheres as Potential Intravitreal Depot Formulation for Glaucoma Therapy.
Pharmaceutics 12 (8), S. 706.
, Studnitz, Annabel, Priglinger, Siegfried G., Fuchshofer, Rudolf, Luft, Nikolaus, Moloney, Gregory, Dirisamer, Martin und Ohlmann, Andreas
(2020)
Ex vivo excimer laser ablation of cornea guttata and ROCK inhibitor‐aided endothelial recolonization of ablated central cornea.
Acta Ophthalmologica 98 (6).
Volltext nicht vorhanden.
, Tamm, Ernst R.
und Ohlmann, Andreas
(2020)
Endogenous Wnt/β-catenin signaling in Müller cells protects retinal ganglion cells from excitotoxic damage.
Molecular vision 26, S. 135-149.
Volltext nicht vorhanden.
Kassumeh, S.
, Leopold, Stephanie Anna, Fuchshofer, Rudolf, Tamm, Ernst R., Ohlmann, Andreas, make_name_string expected hash reference
und make_name_string expected hash reference
(2020)
Norrin protects retinal ganglion cells from excitotoxic damage via the induction of LIF.
Cells 9, S. 277.
, Ethier, C. Ross, Faralli, Jennifer A., Freddo, Thomas F., Fuchshofer, Rudolf
, Giovingo, Michael, Gong, Haiyan, Gonzalez, Pedro, Huang, Alex, Johnstone, Murray A., Kaufman, Paul L., Kelley, Mary J., Knepper, Paul A., Kopczynski, Casey C., Kuchtey, John G., Kuchtey, Rachel W., Kuehn, Markus H.
, Lieberman, Raquel L., Lin, Shan C., Liton, Paloma, Liu, Yutao, Lütjen-Drecoll, Elke, Mao, Weiming, Masis-Solano, Marisse, McDonnell, Fiona, McDowell, Colleen M., Overby, Darryl R.
, Pattabiraman, Padmanabhan P., Raghunathan, Vijay K.
, Rao, P. Vasanth, Rhee, Douglas J., Chowdhury, Uttio Roy, Russell, Paul, Samples, John R., Schwartz, Donald, Stubbs, Evan B., Tamm, Ernst R., Tan, James C., Toris, Carol B., Torrejon, Karen Y., Vranka, Janice A., Wirtz, Mary K., Yorio, Thomas, Zhang, Jie, Zode, Gulab S., Fautsch, Michael P., Peters, Donna M., Acott, Ted S. und Stamer, W. Daniel
(2018)
Consensus recommendations for trabecular meshwork cell isolation, characterization and culture.
Experimental Eye Research 171, S. 164-173.
Volltext nicht vorhanden.
, Tamm, Ernst R. und Ohlmann, Andreas
(2018)
Cross-Inhibition of Norrin and TGF-β Signaling Modulates Development of Retinal and Choroidal Vasculature.
Investigative Opthalmology & Visual Science 59 (6), S. 2240.
Volltext nicht vorhanden.
(2018)
Intracameral Delivery of Layer‐by‐Layer Coated siRNA Nanoparticles for Glaucoma Therapy.
Small 14 (50), S. 1803239.
Volltext nicht vorhanden.
(2017)
SMAD7 deficiency stimulates Müller progenitor cell proliferation during the development of the mammalian retina.
Histochemistry and Cell Biology 148 (1), S. 21-32.
Volltext nicht vorhanden.
und Fuchshofer, Rudolf
(2016)
Cyclic RGD peptides target human trabecular meshwork cells while ameliorating connective tissue growth factor-induced fibrosis.
Journal of Drug Targeting 24 (10), S. 952-959.
Volltext nicht vorhanden.
, Crespo-Garcia, Sergio
, Skosyrski, Sergej, Herrspiegel, Christina, Kociok, Norbert, Fuchshofer, Rudolf
, Dillinger, Andrea, Poglitsch, Marco, Müller, Dominik N., Joussen, Antonia M., Luft, Friedrich C., Dechend, Ralf und Strauß, Olaf
(2016)
Hypertensive retinopathy in a transgenic angiotensin-based model.
Clinical Science 130 (13), S. 1075-1088.
Volltext nicht vorhanden.
und Tamm, Ernst R.
(2015)
The aqueous humor outflow pathways in glaucoma: A unifying concept of disease mechanisms and causative treatment.
European Journal of Pharmaceutics and Biopharmaceutics 95 (Part B), S. 173-181.
Volltext nicht vorhanden.
Kuespert, Sabrina, Junglas, Benjamin, Braunger, Barbara M.
, Tamm, Ernst R.
und Fuchshofer, Rudolf
(2015)
The regulation of connective tissue growth factor expression influences the viability of human trabecular meshwork cells.
Journal of Cellular and Molecular Medicine 19 (5), S. 1010-1020.
, Burger, Maximilian und Bründl, Johannes
(2015)
Anatomical Study of Pelvic Nerves in Relation to Seminal Vesicles, Prostate and Urethral Sphincter: Immunohistochemical Staining, Computerized Planimetry and 3-Dimensional Reconstruction.
Journal of Urology 193 (4), S. 1205-1212.
Volltext nicht vorhanden.
, Kleiter, Ingo, Aigner, Ludwig, Tamm, Ernst R. und Braunger, Barbara M.
(2015)
Heterozygous modulation of TGF-β signaling does not influence Müller glia cell reactivity or proliferation following NMDA-induced damage.
Histochemistry and Cell Biology 144 (5), S. 443-455.
Volltext nicht vorhanden.
, Braunger, Barbara M. und Fuchshofer, Rudolf
(2015)
18. Intraocular Pressure and the Mechanisms Involved in Resistance of the Aqueous Humor Flow in the Trabecular Meshwork Outflow Pathways.
In: Fielding Hejtmancik, J. und Nickerson, John M., (eds.)
Molecular Biology of Eye Disease.
Progress in Molecular Biology and Translational Science, 134 (18).
Elsevier, Amsterdam, S. 301-314.
ISBN 978-0-12-801059-4.
Volltext nicht vorhanden.
, Plößl, Karolina, Schneider, Magdalena, Grassmann, Felix
, Fuchshofer, Rudolf
, Tiefenbach, Klaus-Jürgen, Längst, Gernot und Weber, Bernhard H. F.
(2015)
Synonymous variants in HTRA1 implicated in AMD susceptibility impair its capacity to regulate TGF-β signaling.
Human Molecular Genetics 24, S. 6361-6373.
Volltext nicht vorhanden.
, Zhou, Enhua H., Vargas-Pinto, Rocio, Pedrigi, Ryan M., Fuchshofer, Rudolf
, Braakman, Sietse T.
, Gupta, Ritika, Perkumas, Kristin M., Sherwood, Joseph M., Vahabikashi, Amir, Dang, Quynh, Kim, Jae Hun, Ethier, C. Ross, Stamer, W. Daniel, Fredberg, Jeffrey J. und Johnson, Mark
(2014)
Altered mechanobiology of Schlemm’s canal endothelial cells in glaucoma.
Proceedings of the National Academy of Sciences 111 (38), S. 13876-13881.
Volltext nicht vorhanden.
, Braunger, Barbara M.
, Iwata, Takeshi und Tamm, Ernst R.
(2014)
Heterozygote Wdr36-deficient mice do not develop glaucoma.
Experimental Eye Research 128, S. 83-91.
Volltext nicht vorhanden.
, Ademoglu, Bahar, Koschade, Sebastian E., Fuchshofer, Rudolf
, Gabelt, B'Ann T., Kiland, Julie A., Hennes-Beann, Elizabeth A., Brunner, Kevin G., Kaufman, Paul L. und Tamm, Ernst R.
(2014)
Identification of Adult Stem Cells in Schwalbe's Line Region of the Primate Eye.
Investigative Opthalmology & Visual Science 55 (11), S. 7499.
Volltext nicht vorhanden.
und Tamm, Ernst R.
(2014)
Optineurin associates with the podocyte Golgi complex to maintain its structure.
Cell and Tissue Research 358 (2), S. 567-583.
Volltext nicht vorhanden.
, Kuespert, Sabrina, Junglas, Benjamin und Tamm, Ernst R.
(2014)
The Prostaglandin F2α Analog Fluprostenol Attenuates the Fibrotic Effects of Connective Tissue Growth Factor on Human Trabecular Meshwork Cells.
Journal of Ocular Pharmacology and Therapeutics 30 (2-3), S. 237-245.
Volltext nicht vorhanden.
, Wenzel, Rebecca, Breunig, Miriam
, Tessmar, Joerg
, Tamm, Ernst R.
und Goepferich, Achim
(2013)
Ligand-functionalized nanoparticles target endothelial cells in retinal capillaries after systemic application.
Proceedings of the National Academy of Sciences of the United States of America (PNAS) 110 (15), S. 6115-6120.
Volltext nicht vorhanden.
, Struller, Tobias, Ullmann, Sabrina, Bösl, Michael, Bosserhoff, Anja
, Köstler, Josef, Wagner, Ralf, Tamm, Ernst R.
und Fuchshofer, Rudolf
(2012)
Connective Tissue Growth Factor Causes Glaucoma by Modifying the Actin Cytoskeleton of the Trabecular Meshwork.
The American Journal of Pathology 180 (6), S. 2386-2403.
Volltext nicht vorhanden.
und Langmann, Thomas
(2012)
Erratum to: Luteolin triggers global changes in the microglial transcriptome leading to a unique anti-inflammatory and neuroprotective phenotype.
Journal of Neuroinflammation 9 (1).
Volltext nicht vorhanden.
und Tamm, Ernst R.
(2012)
Lack of endothelial diaphragms in fenestrae and caveolae of mutant Plvap-deficient mice.
Histochemistry and Cell Biology 138 (5), S. 709-724.
Volltext nicht vorhanden.
und Tamm, Ernst R.
(2012)
The role of TGF-β in the pathogenesis of primary open-angle glaucoma.
Cell and Tissue Research 347 (1), S. 279-290.
Volltext nicht vorhanden.
, Ullmann, Sabrina, Zeilbeck, Ludwig F., Baumann, Matti, Junglas, Benjamin und Tamm, Ernst R.
(2011)
Connective tissue growth factor modulates podocyte actin cytoskeleton and extracellular matrix synthesis and is induced in podocytes upon injury.
Histochemistry and Cell Biology 136 (3), S. 301-319.
Volltext nicht vorhanden.
, Tamm, Ernst R.
und Hillenkamp, Jost
(2011)
Different collagen types define two types of idiopathic epiretinal membranes.
Histopathology 58 (6), S. 953-965.
Volltext nicht vorhanden.
(2011)
The pathogenic role of transforming growth factor-β2 in glaucomatous damage to the optic nerve head.
Experimental Eye Research 93 (2), S. 165-169.
Volltext nicht vorhanden.
und Langmann, Thomas
(2010)
Luteolin triggers global changes in the microglial transcriptome leading to a unique anti-inflammatory and neuroprotective phenotype.
Journal of Neuroinflammation 7 (1).
Volltext nicht vorhanden.
und Langmann, Thomas
(2010)
The Novel Activated Microglia/Macrophage WAP Domain Protein, AMWAP, Acts as a Counter-Regulator of Proinflammatory Response.
The Journal of Immunology 185 (6), S. 3379-3390.
Volltext nicht vorhanden.
und Fuchshofer, Rudolf
(2009)
Connective tissue growth factor induces extracellular matrix deposition in human trabecular meshwork cells.
Experimental Eye Research 88 (6), S. 1065-1075.
Volltext nicht vorhanden.
, Stephan, Dietrich A., Russell, Paul und Tamm, Ernst R.
(2009)
Gene expression profiling of TGFβ2- and/or BMP7-treated trabecular meshwork cells: Identification of Smad7 as a critical inhibitor of TGF-β2 signaling.
Experimental Eye Research 88 (6), S. 1020-1032.
Volltext nicht vorhanden.
, Yu, Alice L., Teng, Hiang-Hwa, Strauss, Rupert, Kampik, Anselm und Welge-Lussen, Ulrich
(2009)
Hypoxia/reoxygenation induces CTGF and PAI-1 in cultured human retinal pigment epithelium cells.
Experimental Eye Research 88 (5), S. 889-899.
Volltext nicht vorhanden.
und Tamm, Ernst R.
(2009)
Modulation of extracellular matrix turnover in the trabecular meshwork.
Experimental Eye Research 88 (4), S. 683-688.
Volltext nicht vorhanden.
, Kook, Daniel, Kampik, Anselm, Bloemendal, Hans und Welge-Lu¨ssen, Ulrich
(2009)
Subtoxic Oxidative Stress Induces Senescence in Retinal Pigment Epithelial Cells via TGF-β Release.
Investigative Opthalmology & Visual Science 50 (2), S. 926.
Volltext nicht vorhanden.
, Wegner, Michael
und Tamm, Ernst R.
(2008)
Anterior segment dysgenesis in the eyes of mice deficient for the high-mobility-group transcription factor Sox11.
Experimental Eye Research 86 (6), S. 895-907.
Volltext nicht vorhanden.
, Kampik, Anselm und Welge-Lu¨ssen, Ulrich
(2008)
Effects of Oxidative Stress in Trabecular Meshwork Cells Are Reduced by Prostaglandin Analogues.
Investigative Opthalmology & Visual Science 49 (11), S. 4872.
Volltext nicht vorhanden.
, Russell, Paul und Tamm, Ernst R.
(2008)
Elevated amounts of myocilin in the aqueous humor of transgenic mice cause significant changes in ocular gene expression.
Experimental Eye Research 87 (3), S. 257-267.
Volltext nicht vorhanden.
, Birke, Marco, Kampik, Anselm, Bloemendal, Hans und Welge-Lu¨ssen, Ulrich
(2008)
Oxidative Stress and TGF-β2 Increase Heat Shock Protein 27 Expression in Human Optic Nerve Head Astrocytes.
Investigative Opthalmology & Visual Science 49 (12), S. 5403.
Volltext nicht vorhanden.
, Yu, Alice H. L., Welge-Lüssen, Ulrich und Tamm, Ernst R.
(2007)
Bone Morphogenetic Protein-7 Is an Antagonist of Transforming Growth Factor-β2 in Human Trabecular Meshwork Cells.
Investigative Opthalmology & Visual Science 48 (2), S. 715-726.
Volltext nicht vorhanden.
, Birke, Marco, Priglinger, Siegfried G., Eibl, Kirsten H., Kampik, Anselm, Bloemendal, Hans und Welge-Lussen, Ulrich
(2007)
Hypoxia/reoxygenation and TGF-β increase αB-crystallin expression in human optic nerve head astrocytes.
Experimental Eye Research 84 (4), S. 694-706.
Volltext nicht vorhanden.
(2007)
What Increases Outflow Resistance in Primary Open-angle Glaucoma?
Survey of Ophthalmology 52 (6), S101-S104.
Volltext nicht vorhanden.
, Welge-Lüssen, Ulrich und Tamm, Ernst R.
(2004)
Thrombospondin-1 in the trabecular meshwork: localization in normal and glaucomatous eyes, and induction by TGF-β1 and dexamethasone in vitro.
Experimental Eye Research 79 (5), S. 649-663.
Volltext nicht vorhanden.
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