Other Projects

Höring, Carina (2023) Split-Luciferase Complementation and Molecular Dynamics Studies for the Mini-G Protein-Based Functional Characterization of GPCRs. PhD, Universität Regensburg.

Bartole, Edith (2021) Design, Synthesis and Characterization of Molecular Tools for the Histamine H3 and H4 Receptors – In Particular Radio- and Fluorescent Ligands. PhD, Universität Regensburg.

Littmann, Timo (2020) Towards a method for the simultaneous quantification of Gαq activation β-arrestin2 recruitment. PhD, Universität Regensburg.

Gienger, Marie, Hübner, Harald, Löber, Stefan, König, Burkhard and Gmeiner, Peter (2020) Structure-based development of caged dopamine D2/D3 receptor antagonists. Scientific Reports, p. 829.

Rustler, Karin , Pockes, Steffen and König, Burkhard (2019) Light-Switchable Antagonists for the Histamine H1 Receptor at the Isolated Guinea Pig Ileum. ChemMedChem 14 (6), pp. 636-644. Fulltext not available.

Lachmann, Daniel, Lahmy, Ranit and König, Burkhard (2019) Fulgimides as light-activated tools in biological investigations. European Journal of Organic Chemistry, pp. 5018-5024. Fulltext not available.

Lachmann, Daniel, Konieczny, Adam, Keller, Max and König, Burkhard (2019) Photochromic peptidic NPY Y4-receptor ligands. Organic & Biomolecular Chemistry 17, pp. 2467-2478. Fulltext not available.

Dukorn, Stefanie, Littmann, Timo, Keller, Max, Kuhn, Kilian K., Cabrele, Chiara , Baumeister, Paul, Bernhardt, Günther and Buschauer, Armin (2017) Fluorescence- and radio-labeling of Lys4,Nle17,30hPP yields molecular tools for the NPY Y4 receptor. Bioconjugate Chemistry. Fulltext not available.

Keller, Max , Maschauer, Simone, Brennauer, Albert, Tripal, Philipp, Koglin, Norman, Dittrich, Ralf, Bernhardt, Günther, Kuwert, Torsten, Wester, Hans-Jürgen, Buschauer, Armin and Prante, Olaf (2017) Prototypic 18F-Labeled Argininamide-Type Neuropeptide Y Y1R Antagonists as Tracers for PET Imaging of Mammary Carcinoma. ACS Medicinal Chemistry Letters 8, pp. 304-309. Fulltext not available.

Simeth, Nadja Anita , Bause, Manuel, Dobmeier, Michael, Kling, Ralf C., Lachmann, Daniel, Hübner, Harald, Einsiedel, Jürgen, Gmeiner, Peter and König, Burkhard (2017) NTS2-selective neurotensin mimetics with tetrahydrofuran amino acids. Bioorganic & Medicinal Chemistry 1, pp. 350-359. Fulltext not available.

Lachmann, Daniel, Studte, Carolin, Männel, Barbara, Hübner, Harald, Gmeiner, Peter and König, Burkhard (2017) Photochromic Dopamine Receptor Ligands Based on
Dithienylethenes and Fulgides. Chemistry - A European Journal 23, pp. 13423-13434. Fulltext not available.

Lieb, Sebastian, Littmann, Timo, Plank, Nicole, Felixberger, Johannes, Tanaka, Miho, Schäfer, Thorsten, Krief, Stéphane, Elz, Sigurd, Friedland, Kristina, Bernhardt, Günther, Wegener, Joachim, Ozawa, Takeaki and Buschauer, Armin (2016) Label-free versus conventional cellular assays: functional investigations on the human histamine H1 receptor. Pharmacological Research 114, pp. 13-26. Fulltext not available.

Kuhn, Kilian K., Ertl, Thomas, Dukorn, Stefanie, Keller, Max, Bernhardt, Günther, Reiser, Oliver and Buschauer, Armin (2016) High affinity agonists of the neuropeptide Y (NPY) Y4 receptor derived from the C-terminal pentapeptide of human pancreatic polypeptide (hPP): synthesis, stereochemical discrimination and radiolabeling. Journal of Medicinal Chemistry 59 (13), pp. 6045-6058. Fulltext not available.

Geyer, Roland, Nordemann, Uwe, Strasser, Andrea, Wittmann, Hans-Joachim and Buschauer, Armin (2016) Conformational restriction and enantioseparation increase potency and selectivity of cyanoguanidine-type histamine H4 receptor agonists. Journal of Medicinal Chemistry 59 (7), pp. 3452-3470. Fulltext not available.

Lieb, Sebastian, Michaelis, Stefanie, Plank, Nicole, Bernhardt, Günther, Buschauer, Armin and Wegener, Joachim (2016) Label-free analysis of GPCR-stimulation: The critical impact of cell adhesion. Pharmacological Research 108 (June), pp. 65-74. Fulltext not available.

Keller, Max, Kuhn, Kilian K., Einsiedel, Jürgen, Hübner, Harald, Biselli, Sabrina, Mollereau, Catherine , Wifling, David, Svobodova, Jaroslava, Bernhardt, Günther, Cabrele, Chiara , Vanderheyden, Patrick, Gmeiner, Peter and Buschauer, Armin (2016) Mimicking of arginine by functionalized Nω-carbamoylated arginine as a new broadly applicable approach to labeled bioactive peptides: high affinity angiotensin, neuropeptide Y, neuropeptide FF and neurotensin receptor ligands as examples. Journal of Medicinal Chemistry 59 (5), pp. 1925-1945. Fulltext not available.

Werner, Kristin, Kälble, Solveig, Wolter, Sabine, Schneider, Erich H. , Buschauer, Armin, Neumann, Detlef and Seifert, Roland (2015) Flow cytometric analysis with a fluorescent formyl peptide receptor ligand as a new method to study the pharmacological profile of the histamine H2-receptor. Naunyn Schmiedebergs Archives of Pharmacology 388 (10), pp. 1039-1052. Fulltext not available.

Keller, Max, Schindler, Lisa, Bernhardt, Günther and Buschauer, Armin (2015) Towards labeled argininamide-type NPY Y1 receptor antagonists: Identification of a favorable propionylation site in BIBO3304. Archiv der Pharmazie 348 (6), pp. 390-398. Fulltext not available.

Wutz, Daniel, Falenczyk, Carolin, Kuzmanovic, Natascha and König, Burkhard (2015) Functionalization of Photochromic Dithienylmaleimides. RSC Advances 5, pp. 18075-18086.

Wifling, David , Bernhardt, Günther, Dove, Stefan and Buschauer, Armin (2015) The extracellular loop 2 (ECL2) of the human histamine H4 receptor substantially contributes to ligand binding and constitutive activity. PLoS One 10 (1), pp. 1-14.

Baumeister, Paul, Erdmann, Daniela, Biselli, Sabrina, Kagermeier, Nicole, Elz, Sigurd, Bernhardt, Günther and Buschauer, Armin (2015) 3HUR-DE257: Development of a tritium-labeled squaramide-type selective histamine H2 receptor antagonist. ChemMedChem 10 (1), pp. 83-93. Fulltext not available.

Kagermeier, Nicole, Werner, Kristin, Keller, Max, Baumeister, Paul, Bernhardt, Günther, Seifert, Roland and Buschauer, Armin (2015) Dimeric carbamoylguanidine-type histamine H2 receptor ligands: A new class of potent and selective agonists. Bioorganic & Medicinal Chemistry 23 (14), pp. 3957-3969. Fulltext not available.

Keller, Max, Tränkle, Christian, She, Xueke, Pegoli, Andrea , Bernhardt, Günther, Buschauer, Armin and Read, Roger W. (2015) M2 subtype preferring dibenzodiazepinone-type muscarinic receptor ligands: effect of chemical homo-dimerization on orthosteric (and allosteric?) binding. Bioorganic & Medicinal Chemistry 23 (14), pp. 3970-3990. Fulltext not available.

Keller, Max, Weiss, Stefan, Hutzler, Christoph , Kuhn, Kilian K., Mollereau, Catherine , Dukorn, Stefanie, Schindler, Lisa, Bernhardt, Günther, König, Burkhard and Buschauer, Armin (2015) N(omega)-carbamoylation of the argininamide moiety: an avenue to insurmountable NPY Y1 receptor antagonists and a radiolabeled selective high affinity molecular tool ([3H]UR-MK299) with extended residence time. Journal of Medicinal Chemistry 58 (22), pp. 8834-8849. Fulltext not available.

Reisinger, Bernd, Kuzmanovic, Natascha, Löffler, Patrick, Merkl, Rainer , König, Burkhard and Sterner, Reinhard (2014) Exploiting Protein Symmetry To Design Light-Controllable Enzyme Inhibitors. Angewandte Chemie International Edition 53, pp. 595-598. Fulltext not available.

Werner, Kristin, Neumann, Detlef , Buschauer, Armin and Seifert, Roland (2014) No evidence for histamine H4-receptor in human monocytes. Journal of Pharmacology and Experimental Therapeutics 351 (3), pp. 519-526. Fulltext not available.

Dove, Stefan and Buschauer, Armin (2013) G-Protein-gekoppelte Rezeptoren: „Sinnesorgane“ der Zellen. Blick in die Wissenschaft 22 (28), pp. 3-9. Fulltext not available.

Keller, Max, Kaske, Melanie, Holzammer, Tobias, Bernhardt, Günther and Buschauer, Armin (2013) Dimeric argininamide-type neuropeptide Y receptor antagonists: chiral discrimination between Y1 and Y4 receptors. Bioorganic and Medicinal Chemistry 21 (21), pp. 6303-6322. Fulltext not available.

Berlicki, Lukasz , Kaske, Melanie, Gutierrez-Abad, Raquel, Bernhardt, Günther, Illa, Ona , Ortuño, Rosa, Cabrele, Chiara , Buschauer, Armin and Reiser, Oliver (2013) Replacement of Thr32 and Gln34 in the C-terminal neuropeptide Y fragment 25-36 by cis-cyclobutane- and cis-cyclopentane β-amino acids shifts selectivity toward the Y4 receptor. Journal of Medicinal Chemistry 56 (21), pp. 8422-8431. Fulltext not available.