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Artikel
Harrer, Dennis Christoph 
, Schlierkamp-Voosen, Tim, Barden, Markus, Pan, Hong, Xydia, Maria, Herr, Wolfgang, Dörrie, Jan, Schaft, Niels und Abken, Hinrich
(2025)
Chimeric Antigen Receptor (CAR) T Cells Releasing Soluble SLAMF6 Isoform 2 Gain Superior Anti-Cancer Cell Functionality in an Auto-Stimulatory Fashion.
Cells 14 (12), S. 901.
Harrer, Dennis Christoph , Eder, Matthias, Barden, Markus, Pan, Hong, Herr, Wolfgang und Abken, Hinrich
(2024)
Ectopic PU.1 Expression Provides Chimeric Antigen Receptor (CAR) T Cells with Innate Cell Capacities Including IFN-β Release.
Cancers 16 (15), S. 2737.
Harrer, Dennis Christoph , Li, Sin-Syue, Kaljanac, Marcell, Bezler, Valerie, Barden, Markus, Pan, Hong, Herr, Wolfgang und Abken, Hinrich
(2024)
Magnetic CAR T cell purification using an anti-G4S linker antibody.
Journal of Immunological Methods 528, S. 113667.
Delacher, Michael , Schmidleithner, Lisa , Simon, Malte , Stüve, Philipp , Sanderink, Lieke , Hotz-Wagenblatt, Agnes, Wuttke, Marina , Schambeck, Kathrin , Ruhland, Brigitte , Hofmann, Veronika , Bittner, Sebastian , Ritter, Uwe , Pant, Asmita , Helbich, Sara Salome, Voss, Morten, Lemmermann, Niels A., Bessiri-Schake, Lisa, Bohn, Toszka, Eigenberger, Andreas , Menevse, Ayse Nur , Gebhard, Claudia , Strieder, Nicholas , Abken, Hinrich , Rehli, Michael , Huehn, Jochen, Beckhove, Philipp , Hehlgans, Thomas , Junger, Henrik , Geissler, Edward K. , Prantl, Lukas , Werner, Jens M. , Schmidl, Christian , Brors, Benedikt, Imbusch, Charles D. und Feuerer, Markus
(2024)
The effector program of human CD8 T cells supports tissue remodeling.
Journal of Experimental Medicine 221 (2), e20230488.
Harrer, Dennis Christoph , Li, Sin-Syue, Kaljanac, Marcell, Barden, Markus, Pan, Hong und Abken, Hinrich
(2023)
Fine-tuning the antigen sensitivity of CAR T cells: emerging strategies and current challenges.
Frontiers in Immunology 14.
Harrer, Dennis Christoph , Bezler, Valerie, Hartley, Jordan, Herr, Wolfgang und Abken, Hinrich
(2023)
IRF4 downregulation improves sensitivity and endurance of CAR T cell functional capacities.
Frontiers in Immunology 14.
Thomas, Simone und Abken, Hinrich
(2023)
CAR T cell therapy becomes CHIC: “cytokine help intensified CAR” T cells.
Frontiers in Immunology 13.
Kaljanac, Marcell und Abken, Hinrich
(2023)
Do Treg Speed Up with CARs? Chimeric Antigen Receptor Treg Engineered to Induce Transplant Tolerance.
Transplantation 107 (1), S. 74-85.
Hombach, Andreas A., Ambrose, Christine, Lobb, Roy, Rennert, Paul und Abken, Hinrich
(2023)
A CD19-Anti-ErbB2 scFv Engager Protein Enables CD19-Specific CAR T Cells to Eradicate ErbB2+ Solid Cancer.
Cells 12 (2), S. 248.
Volltext nicht vorhanden.
Altvater, Bianca, Kailayangiri, Sareetha, Spurny, Christian, Flügge, Maike, Meltzer, Jutta, Greune, Lea, Urban, Katja, Schwöppe, Christian, Brand, Caroline, Schliemann, Christoph, Hintelmann, Heike, Harrach, Saliha, Hartmann, Wolfgang, Abken, Hinrich, Kuehle, Johannes, Schambach, Axel, Görlich, Dennis, Berdel, Wolfgang E. und Rossig, Claudia
(2023)
CAR T cells as micropharmacies against solid cancers: Combining effector T-cell mediated cell death with vascular targeting in a one-step engineering process.
Cancer Gene Therapy 30 (10), S. 1355-1368.
Volltext nicht vorhanden.
Barden, Markus, Holzinger, Astrid, Velas, Lukas, Mezősi-Csaplár, Marianna, Szöőr, Árpád, Vereb, György, Schütz, Gerhard J., Hombach, Andreas A. und Abken, Hinrich
(2023)
CAR and TCR form individual signaling synapses and do not cross-activate, however, can co-operate in T cell activation.
Frontiers in Immunology 14.
Volltext nicht vorhanden.
Ciulean, Ioana Sonya, Fischer, Joe, Quaiser, Andrea, Bach, Christoph, Abken, Hinrich, Tretbar, Uta Sandy, Fricke, Stephan, Koehl, Ulrike, Schmiedel, Dominik und Grunwald, Thomas
(2023)
CD44v6 specific CAR-NK cells for targeted immunotherapy of head and neck squamous cell carcinoma.
Frontiers in Immunology 14.
Volltext nicht vorhanden.
Soto, Karla E. G., Loureiro, Liliana R., Bartsch, Tabea, Arndt, Claudia, Kegler, Alexandra, Mitwasi, Nicola, Drewitz, Laura, Hoffmann, Lydia, Saleh, Haidy A., Crespo, Eugenia, Mehnert, Maria, Daglar, Cansu, Abken, Hinrich, Momburg, Frank, Bachmann, Michael und Feldmann, Anja
(2023)
Targeting colorectal cancer cells using AND-gated adaptor RevCAR T-cells.
Frontiers in Immunology 14.
Volltext nicht vorhanden.
Harrer, Dennis Christoph , Schenkel, Charlotte, Bezler, Valerie, Kaljanac, Marcell, Hartley, Jordan, Barden, Markus, Pan, Hong, Holzinger, Astrid, Herr, Wolfgang und Abken, Hinrich
(2022)
CAR Triggered Release of Type-1 Interferon Limits CAR T-Cell Activities by an Artificial Negative Autocrine Loop.
Cells 11 (23), S. 3839.
Holzinger, Astrid und Abken, Hinrich
(2022)
Treatment with Living Drugs: Pharmaceutical Aspects of CAR T Cells.
Pharmacology 107 (9-10), S. 446-463.
Garofano, Francesca , Sharma, Amit , Abken, Hinrich, Gonzalez-Carmona, Maria A. und Schmidt-Wolf, Ingo G. H.
(2022)
A Low Dose of Pure Cannabidiol Is Sufficient to Stimulate the Cytotoxic Function of CIK Cells without Exerting the Downstream Mediators in Pancreatic Cancer Cells.
International Journal of Molecular Sciences 23 (7), S. 3783.
Volltext nicht vorhanden.
, Sharma, Amit , Abken, Hinrich, Gonzalez-Carmona, Maria A. und Schmidt-Wolf, Ingo G. H.
(2022)
A Low Dose of Pure Cannabidiol Is Sufficient to Stimulate the Cytotoxic Function of CIK Cells without Exerting the Downstream Mediators in Pancreatic Cancer Cells.
International Journal of Molecular Sciences 23 (7), S. 3783.
Volltext nicht vorhanden.
Harrer, Dennis Christoph, Schenkel, Charlotte, Berking, Carola, Herr, Wolfgang, Abken, Hinrich , Dörrie, Jan und Schaft, Niels
(2022)
Decitabine-Mediated Upregulation of CSPG4 in Ovarian Carcinoma Cells Enables Targeting by CSPG4-Specific CAR-T Cells.
Cancers 14 (20), S. 5033.
Volltext nicht vorhanden.
, Dörrie, Jan und Schaft, Niels
(2022)
Decitabine-Mediated Upregulation of CSPG4 in Ovarian Carcinoma Cells Enables Targeting by CSPG4-Specific CAR-T Cells.
Cancers 14 (20), S. 5033.
Volltext nicht vorhanden.
Balta, Emre, Janzen, Nina, Kirchgessner, Henning, Toufaki, Vasiliki, Orlik, Christian, Liang, Jie, Lairikyengbam, Divya, Abken, Hinrich, Niesler, Beate, Müller-Decker, Karin, Ruppert, Thomas und Samstag, Yvonne
(2022)
Expression of TRX1 optimizes the antitumor functions of human CAR T cells and confers resistance to a pro-oxidative tumor microenvironment.
Frontiers in Immunology 13.
Volltext nicht vorhanden.
Hombach, Andreas, Barden, Markus, Hannappel, Lisa, Chmielewski, Markus, Rappl, Gunter, Sachinidis, Agapios und Abken, Hinrich
(2022)
IL12 integrated into the CAR exodomain converts CD8+ T cells to poly-functional NK-like cells with superior killing of antigen-loss tumors.
Molecular Therapy 30 (2), S. 593-605.
Volltext nicht vorhanden.
Ramos, Joe W., Ambrose, Christine, Su, Lihe, Wu, Lan, Dufort, Fay J., Sanford, Thomas, Birt, Alyssa, Hackel, Benjamin J., Hombach, Andreas, Abken, Hinrich, Lobb, Roy R. und Rennert, Paul D.
(2021)
Anti-CD19 CAR T cells potently redirected to kill solid tumor cells.
PLOS ONE 16 (3), e0247701.
Volltext nicht vorhanden.
Köhl, Ulrike und Abken, Hinrich
(2021)
CAR-T-Zellen als Arzneimittel für neuartige Therapien (Advanced Therapy Medicinal Products).
Der Internist 62 (4), S. 449-457.
Volltext nicht vorhanden.
Bunse, Mario, Pfeilschifter, Janina, Bluhm, Julia, Zschummel, Maria, Joedicke, Jara J., Wirges, Anthea, Stark, Helen, Kretschmer, Vivien, Chmielewski, Markus, Uckert, Wolfgang, Abken, Hinrich , Westermann, Jörg, Rehm, Armin und Höpken, Uta E.
(2021)
CXCR5 CAR-T cells simultaneously target B cell non-Hodgkin’s lymphoma and tumor-supportive follicular T helper cells.
Nature Communications 12 (1).
Volltext nicht vorhanden.
, Westermann, Jörg, Rehm, Armin und Höpken, Uta E.
(2021)
CXCR5 CAR-T cells simultaneously target B cell non-Hodgkin’s lymphoma and tumor-supportive follicular T helper cells.
Nature Communications 12 (1).
Volltext nicht vorhanden.
Rudek, Loreen Sophie, Zimmermann, Katharina, Galla, Melanie, Meyer, Johann, Kuehle, Johannes, Stamopoulou, Andriana, Brand, Daniel, Sandalcioglu, I. Erol, Neyazi, Belal, Moritz, Thomas, Rossig, Claudia, Altvater, Bianca, Falk, Christine S., Abken, Hinrich, Morgan, Michael Alexander und Schambach, Axel
(2021)
Generation of an NFκB-Driven Alpharetroviral “All-in-One” Vector Construct as a Potent Tool for CAR NK Cell Therapy.
Frontiers in Immunology 12.
Volltext nicht vorhanden.
Hombach, Andreas A., Geumann, Ulf, Günther, Christine, Hermann, Felix G. und Abken, Hinrich
(2020)
IL7-IL12 Engineered Mesenchymal Stem Cells (MSCs) Improve A CAR T Cell Attack Against Colorectal Cancer Cells.
Cells 9 (4), S. 873.
Tóth, G., Szöllősi, J. und Abken, Hinrich
(2020)
A Small Number of HER2 Redirected CAR T Cells Significantly Improves Immune Response of Adoptively Transferred Mouse Lymphocytes against Human Breast Cancer Xenografts.
International Journal of Molecular Sciences 21 (3), S. 1039.
Dragon, Anna Christina , Zimmermann, Katharina, Nerreter, Thomas, Sandfort, Deborah, Lahrberg, Julia, Klöß, Stephan, Kloth, Christina, Mangare, Caroline, Bonifacius, Agnes, Tischer-Zimmermann, Sabine, Blasczyk, Rainer, Maecker-Kolhoff, Britta, Uchanska-Ziegler, Barbara, Abken, Hinrich, Schambach, Axel, Hudecek, Michael und Eiz-Vesper, Britta
(2020)
CAR-T cells and TRUCKs that recognize an EBNA-3C-derived epitope presented on HLA-B*35 control Epstein-Barr virus-associated lymphoproliferation.
Journal for ImmunoTherapy of Cancer 8 (2), e000736.
Volltext nicht vorhanden.
, Zimmermann, Katharina, Nerreter, Thomas, Sandfort, Deborah, Lahrberg, Julia, Klöß, Stephan, Kloth, Christina, Mangare, Caroline, Bonifacius, Agnes, Tischer-Zimmermann, Sabine, Blasczyk, Rainer, Maecker-Kolhoff, Britta, Uchanska-Ziegler, Barbara, Abken, Hinrich, Schambach, Axel, Hudecek, Michael und Eiz-Vesper, Britta
(2020)
CAR-T cells and TRUCKs that recognize an EBNA-3C-derived epitope presented on HLA-B*35 control Epstein-Barr virus-associated lymphoproliferation.
Journal for ImmunoTherapy of Cancer 8 (2), e000736.
Volltext nicht vorhanden.
Nemade, Harshal, Acharya, Aviseka, Chaudhari, Umesh , Nembo, Erastus, Nguemo, Filomain , Riet, Nicole, Abken, Hinrich, Hescheler, Jürgen, Papadopoulos, Symeon und Sachinidis, Agapios
(2020)
Cyclooxygenases Inhibitors Efficiently Induce Cardiomyogenesis in Human Pluripotent Stem Cells.
Cells 9 (3), S. 554.
Volltext nicht vorhanden.
, Nembo, Erastus, Nguemo, Filomain , Riet, Nicole, Abken, Hinrich, Hescheler, Jürgen, Papadopoulos, Symeon und Sachinidis, Agapios
(2020)
Cyclooxygenases Inhibitors Efficiently Induce Cardiomyogenesis in Human Pluripotent Stem Cells.
Cells 9 (3), S. 554.
Volltext nicht vorhanden.
Zimmermann, Katharina, Kuehle, Johannes, Dragon, Anna Christina , Galla, Melanie, Kloth, Christina, Rudek, Loreen Sophie, Sandalcioglu, I. Erol, Neyazi, Belal, Moritz, Thomas, Meyer, Johann, Rossig, Claudia, Altvater, Bianca, Eiz-Vesper, Britta, Morgan, Michael Alexander, Abken, Hinrich und Schambach, Axel
(2020)
Design and Characterization of an “All-in-One” Lentiviral Vector System Combining Constitutive Anti-GD2 CAR Expression and Inducible Cytokines.
Cancers 12 (2), S. 375.
Volltext nicht vorhanden.
, Galla, Melanie, Kloth, Christina, Rudek, Loreen Sophie, Sandalcioglu, I. Erol, Neyazi, Belal, Moritz, Thomas, Meyer, Johann, Rossig, Claudia, Altvater, Bianca, Eiz-Vesper, Britta, Morgan, Michael Alexander, Abken, Hinrich und Schambach, Axel
(2020)
Design and Characterization of an “All-in-One” Lentiviral Vector System Combining Constitutive Anti-GD2 CAR Expression and Inducible Cytokines.
Cancers 12 (2), S. 375.
Volltext nicht vorhanden.
Patasic, Lea, Seifried, Janna, Bezler, Valerie, Kaljanac, Marcell, Schneider, Irene C., Schmitz, Heike, Tondera, Christiane, Hartmann, Jessica, Hombach, Andreas, Buchholz, Christian J., Abken, Hinrich, König, Renate und Cichutek, Klaus
(2020)
Designed Ankyrin Repeat Protein (DARPin) to target chimeric antigen receptor (CAR)-redirected T cells towards CD4+ T cells to reduce the latent HIV+ cell reservoir.
Medical Microbiology and Immunology 209 (6), S. 681-691.
Volltext nicht vorhanden.
Beckhove, Philipp , Edinger, Matthias, Feuerer, Markus, Gattinoni, Luca und Abken, Hinrich
(2020)
International Regensburg Center for Interventional Immunology (RCI) symposium on “Synthetic immunology and environment-adapted redirection of T cells”, 17–18 July, 2019, Regensburg, Germany.
Cancer Immunology, Immunotherapy 69, S. 677-682.
Haumann, Sophie, Boix, Julia, Knuever, Jana, Bieling, Angela, Vila Sanjurjo, Anton, Elson, Joanna L., Blakely, Emma L., Taylor, Robert W., Riet, Nicole, Abken, Hinrich, Kashkar, Hamid, Hornig-Do, Hue-Tran und Wiesner, Rudolf J.
(2020)
Mitochondrial DNA mutations induce mitochondrial biogenesis and increase the tumorigenic potential of Hodgkin and Reed–Sternberg cells.
Carcinogenesis 41 (12), S. 1735-1745.
Volltext nicht vorhanden.
Alzubi, Jamal, Dettmer-Monaco, Viviane, Kuehle, Johannes, Thorausch, Niko, Seidl, Maximilian, Taromi, Sanaz, Schamel, Wolfgang, Zeiser, Robert, Abken, Hinrich, Cathomen, Toni und Wolf, Philipp
(2020)
PSMA-Directed CAR T Cells Combined with Low-Dose Docetaxel Treatment Induce Tumor Regression in a Prostate Cancer Xenograft Model.
Molecular Therapy - Oncolytics 18, S. 226-235.
Volltext nicht vorhanden.
und Wolf, Philipp
(2020)
PSMA-Directed CAR T Cells Combined with Low-Dose Docetaxel Treatment Induce Tumor Regression in a Prostate Cancer Xenograft Model.
Molecular Therapy - Oncolytics 18, S. 226-235.
Volltext nicht vorhanden.
Chmielewski, Markus und Abken, Hinrich
(2020)
TRUCKS, the fourth generation CAR T cells: current developments and clinical translation.
Advances in Cell and Gene Therapy 3, e84.
Szöőr, Árpád, Tóth, Gábor, Zsebik, Barbara, Szabó, Viktória, Eshhar, Zelig, Abken, Hinrich und Vereb, György
(2020)
Trastuzumab derived HER2-specific CARs for the treatment of trastuzumab-resistant breast cancer: CAR T cells penetrate and eradicate tumors that are not accessible to antibodies.
Cancer Letters 484, S. 1-8.
Volltext nicht vorhanden.
Hombach, Andreas A., Rappl, Gunter und Abken, Hinrich
(2019)
Blocking CD30 on T Cells by a Dual Specific CAR for CD30 and Colon Cancer Antigens Improves the CAR T Cell Response against CD30− Tumors.
Molecular Therapy 27 (10), S. 1825-1835.
Volltext nicht vorhanden.
Chmielewski, Markus, Kuehle, Johannes, Chrobok, Danuta, Riet, Nicole, Hallek, Michael und Abken, Hinrich
(2019)
FimH-based display of functional eukaryotic proteins on bacteria surfaces.
Scientific Reports 9 (1).
Volltext nicht vorhanden.
Aleksandrova, Krasimira, Leise, Jana, Priesner, Christoph, Melk, Anette, Kubaink, Fanni, Abken, Hinrich, Hombach, Andreas, Aktas, Murat, Essl, Mike, Bürger, Iris, Kaiser, Andrew, Rauser, Georg, Jurk, Marion, Goudeva, Lilia, Glienke, Wolfgang, Arseniev, Lubomir, Esser, Ruth und Köhl, Ulrike
(2019)
Functionality and Cell Senescence of CD4/ CD8-Selected CD20 CAR T Cells Manufactured Using the Automated CliniMACS Prodigy® Platform.
Transfusion Medicine and Hemotherapy 46 (1), S. 47-54.
Volltext nicht vorhanden.
Golumba-Nagy, Viktória, Kuehle, Johannes, Hombach, Andreas A. und Abken, Hinrich
(2018)
CD28-ζ CAR T Cells Resist TGF-β Repression through IL-2 Signaling, Which Can Be Mimicked by an Engineered IL-7 Autocrine Loop.
Molecular Therapy 26 (9), S. 2218-2230.
Volltext nicht vorhanden.
Probst, Kristina, Stermann, Jacek, von Bomhard, Inga, Etich, Julia , Pitzler, Lena, Niehoff, Anja, Bluhm, Björn, Xu, Haifeng C., Lang, Philipp A., Chmielewski, Markus, Abken, Hinrich, Blissenbach, Birgit, Machova, Alzbeta, Papadopoulou, Nikoletta und Brachvogel, Bent
(2018)
Depletion of Collagen IX Alpha1 Impairs Myeloid Cell Function.
STEM CELLS 36 (11), S. 1752-1763.
Volltext nicht vorhanden.
, Pitzler, Lena, Niehoff, Anja, Bluhm, Björn, Xu, Haifeng C., Lang, Philipp A., Chmielewski, Markus, Abken, Hinrich, Blissenbach, Birgit, Machova, Alzbeta, Papadopoulou, Nikoletta und Brachvogel, Bent
(2018)
Depletion of Collagen IX Alpha1 Impairs Myeloid Cell Function.
STEM CELLS 36 (11), S. 1752-1763.
Volltext nicht vorhanden.
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