Einträge von Grassmann, Felix auf dem Publikationsserver

den Hollander, Anneke I., Mullins, Robert F., Orozco, Luz D., Voigt, Andrew P., Chen, Hsu-Hsin, Strunz, Tobias , Grassmann, Felix, Haines, Jonathan L., Kuiper, Jonas J.W., Tumminia, Santa J., Allikmets, Rando, Hageman, Gregory S., Stambolian, Dwight, Klaver, Caroline C.W., Boeke, Jef D., Chen, Hao, Honigberg, Lee, Katti, Suresh, Frazer, Kelly A. , Weber, Bernhard H.F. und Gorin, Michael B. (2022) Systems genomics in age-related macular degeneration. Experimental Eye Research 225, S. 109248. Volltext nicht vorhanden.

Kiel, Christina , Strunz, Tobias , Grassmann, Felix , Weber, Bernhard H. F. und make_name_string expected hash reference (2020) Pleiotropic Locus 15q24.1 Reveals a Gender-Specific Association with Neovascular but Not Atrophic Age-Related Macular Degeneration (AMD). Cells 9 (10), S. 2257.

Strunz, Tobias , Kiel, Christina , Grassmann, Felix , Ratnapriya, Rinki , Kwicklis, Madeline, Karlstetter, Marcus, Fauser, Sascha, Arend, Nicole, Swaroop, Anand , Langmann, Thomas, Wolf, Armin und Weber, Bernhard H. F. (2020) A mega-analysis of expression quantitative trait loci in retinal tissue. PLOS Genetics 16 (9), e1008934.

Winkler, Thomas W. , Grassmann, Felix , Brandl, Caroline, Kiel, Christina , Günther, Felix, Strunz, Tobias , Weidner, Lorraine, Zimmermann, Martina E., Korb, Christina A., Poplawski, Alicia , Schuster, Alexander K., Müller-Nurasyid, Martina, Peters, Annette , Rauscher, Franziska G., Elze, Tobias, Horn, Katrin, Scholz, Markus, Cañadas-Garre, Marisa, McKnight, Amy Jayne, Quinn, Nicola, Hogg, Ruth E. , Küchenhoff, Helmut, Heid, Iris M., Stark, Klaus J. und Weber, Bernhard H. F. (2020) Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease. BMC Medical Genomics 13, S. 120.

Kiel, Christina , Berber, Patricia, Karlstetter, Marcus, Aslanidis, Alexander, Strunz, Tobias , Langmann, Thomas, Grassmann, Felix und Weber, Bernhard H. F. (2020) A Circulating MicroRNA Profile in a Laser-Induced Mouse Model of Choroidal Neovascularization. International Journal of Molecular Sciences 21 (8), S. 2689. Volltext nicht vorhanden.

Grassmann, Felix , Weber, Bernhard H. F. und Veitia, Reiner A. (2020) Insights into the loss of the Y chromosome with age in control individuals and in patients with age-related macular degeneration using genotyping microarray data. Human Genetics 139 (3), S. 401-407. Volltext nicht vorhanden.

Khan, Mubeen, Cornelis, Stéphanie S., Khan, Muhammad Imran, Elmelik, Duaa, Manders, Eline, Bakker, Sem, Derks, Ronny, Neveling, Kornelia, Vorst, Maartje, Gilissen, Christian, Meunier, Isabelle, Defoort, Sabine, Puech, Bernard, Devos, Aurore, Schulz, Heidi L., Stöhr, Heidi, Grassmann, Felix , Weber, Bernhard H. F., Dhaenens, Claire‐Marie und Cremers, Frans P. M. (2019) Cost‐effective molecular inversion probe‐based ABCA4 sequencing reveals deep‐intronic variants in Stargardt disease. Human Mutation 40 (10), S. 1749-1759. Volltext nicht vorhanden.

Grassmann, Felix , Harsch, Sebastian, Brandl, Caroline , Kiel, Christina, Nürnberg, Peter, Toliat, Mohammad R., Fleckenstein, Monika, Pfau, Maximilian, Schmitz-Valckenberg, Steffen, Holz, Frank G., Chew, Emily Y., Swaroop, Anand, Ratnapriya, Rinki , Klein, Michael L., Mulyukov, Zufar, Zamiri, Parisa und Weber, Bernhard H. F. (2019) Assessment of Novel Genome-Wide Significant Gene Loci and Lesion Growth in Geographic Atrophy Secondary to Age-Related Macular Degeneration. JAMA Ophthalmology 137 (8), S. 867. Volltext nicht vorhanden.

Sangermano, Riccardo , Garanto, Alejandro , Khan, Mubeen, Runhart, Esmee H., Bauwens, Miriam, Bax, Nathalie M., van den Born, L. Ingeborgh, Khan, Muhammad Imran, Cornelis, Stéphanie S., Verheij, Joke B. G. M., Pott, Jan-Willem R., Thiadens, Alberta A. H. J., Klaver, Caroline C. W., Puech, Bernard, Meunier, Isabelle, Naessens, Sarah, Arno, Gavin, Fakin, Ana, Carss, Keren J., Raymond, F. Lucy, Webster, Andrew R., Dhaenens, Claire-Marie, Stöhr, Heidi, Grassmann, Felix , Weber, Bernhard H. F., Hoyng, Carel B., De Baere, Elfride, Albert, Silvia , Collin, Rob W. J. und Cremers, Frans P. M. (2019) Deep-intronic ABCA4 variants explain missing heritability in Stargardt disease and allow correction of splice defects by antisense oligonucleotides. Genetics in Medicine 21 (8), S. 1751-1760. Volltext nicht vorhanden.

Mages, Kristin, Grassmann, Felix , Jägle, Herbert, Rupprecht, Rainer, Weber, Bernhard H. F., Hauck, Stefanie M. und Grosche, Antje (2019) The agonistic TSPO ligand XBD173 attenuates the glial response thereby protecting inner retinal neurons in a murine model of retinal ischemia. Journal of Neuroinflammation 16 (1). Volltext nicht vorhanden.

Grassmann, Felix , Kiel, Christina, den Hollander, Anneke I., Weeks, Daniel E. , Lotery, Andrew , Cipriani, Valentina und Weber, Bernhard H. F. (2019) Y chromosome mosaicism is associated with age-related macular degeneration. European Journal of Human Genetics 27 (1), S. 36-41. Volltext nicht vorhanden.

Pujol-Lereis, Luciana M., Liebisch, Gerhard , Schick, Tina, Lin, Yuchen, Grassmann, Felix , Uchida, Koji, Zipfel, Peter F., Fauser, Sascha, Skerka, Christine und Weber, Bernhard H. F. (2018) Evaluation of serum sphingolipids and the influence of genetic risk factors in age-related macular degeneration. PLOS ONE 13 (8), e0200739.

Winkler, Thomas W. , Brandl, Caroline , Grassmann, Felix , Gorski, Mathias , Stark, Klaus , Loss, Julika, Weber, Bernhard H. F. und Heid, Iris M. (2018) Investigating the modulation of genetic effects on late AMD by age and sex: Lessons learned and two additional loci. PLoS ONE 13 (3), e0194321.

Grassmann, Felix , Mengelkamp, Judith, Brandl, Caroline , Harsch, Sebastian, Zimmermann, Martina E. , Linkohr, Birgit , Peters, Annette, Heid, Iris M., Palm, Christoph und Weber, Bernhard H. F. (2018) A Deep Learning Algorithm for Prediction of Age-Related Eye Disease Study Severity Scale for Age-Related Macular Degeneration from Color Fundus Photography. Ophthalmology 125 (9), S. 1410-1420. Volltext nicht vorhanden.

Strunz, Tobias, Grassmann, Felix , Gayán, Javier, Nahkuri, Satu, Souza-Costa, Debora, Maugeais, Cyrille, Fauser, Sascha, Nogoceke, Everson und Weber, Bernhard H. F. (2018) A mega-analysis of expression quantitative trait loci (eQTL) provides insight into the regulatory architecture of gene expression variation in liver. Scientific Reports 8 (1). Volltext nicht vorhanden.

Cantsilieris, Stuart, Nelson, Bradley J., Huddleston, John, Baker, Carl, Harshman, Lana, Penewit, Kelsi, Munson, Katherine M. , Sorensen, Melanie , Welch, AnneMarie E., Dang, Vy, Grassmann, Felix , Richardson, Andrea J., Guymer, Robyn H. , Graves-Lindsay, Tina A., Wilson, Richard K., Weber, Bernhard H. F., Baird, Paul N., Allikmets, Rando und Eichler, Evan E. (2018) Recurrent structural variation, clustered sites of selection, and disease risk for the complement factor H (CFH) gene family. Proceedings of the National Academy of Sciences 115 (19), E4433-E4442. Volltext nicht vorhanden.

Volz, Cornelia, Grassmann, Felix , Greslechner, Roman, Märker, David Arthur, Peters, Patrick, Helbig, Horst und Gamulescu, Maria-Andreea (2018) Spectral Domain Optical Coherence Tomography Allows the Unification of Clinical Decision Making for the Evaluation of Choroidal Neovascularization Activity. Ophthalmologica 241 (1), S. 32-37. Volltext nicht vorhanden.

Weber, Bernhard H. F., Grassmann, Felix , Kiel, Christina, Zimmermann, Martina E., Gorski, Mathias , Grassmann, Veronika, Stark, Klaus und Heid, Iris M. (2017) Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits. Genome Medicine 9 (29), S. 1-13.

Grassmann, Felix , Heid, Iris M. und Weber, Bernhard H. F. (2017) Recombinant Haplotypes Narrow the ARMS2/HTRA1 Association Signal for Age-Related Macular Degeneration. Genetics 205 (2), S. 919-924.

Micklisch, Sven, Lin, Yuchen, Jacob, Saskia, Karlstetter, Marcus, Dannhausen, Katharina, Dasari, Prasad, von der Heide, Monika, Dahse, Hans-Martin, Schmölz, Lisa, Grassmann, Felix , Alene, Medhanie, Fauser, Sascha, Neumann, Harald, Lorkowski, Stefan , Pauly, Diana und Weber, Bernhard H. F. (2017) Age-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator. Journal of Neuroinflammation 14 (4).

Berber, Patricia, Grassmann, Felix, Kiel, Christina und Weber, Bernhard H. F. (2017) An Eye on Age-Related Macular Degeneration: The Role of MicroRNAs in Disease Pathology. Molecular Diagnosis & Therapy 21 (1), S. 31-43.

Grassmann, Felix und Weber, Bernhard (2017) Genetische Risiken und Therapieentwicklung bei Netzhautdegenerationen. medizinische genetik 29 (2), S. 195-201. Volltext nicht vorhanden.

Brandl, Caroline , Breinlich, Valentin Andreas, Stark, Klaus J., Enzinger, Sabrina, Aßenmacher, Matthias, Olden, Matthias, Grassmann, Felix , Graw, Jochen , Heier, Margit, Peters, Annette , Helbig, Horst, Küchenhoff, Helmut, Weber, Bernhard H. F. und Heid, Iris M. (2016) Features of Age-Related Macular Degeneration in the General Adults and Their Dependency on Age, Sex, and Smoking: Results from the German KORA Study. PLoS ONE 11 (11), e0167181.

Weber, Bernhard H. F. , Grassmann, Felix, Cantsilieris, Stuart, Schulz-Kuhnt, Anja-Sabrina, White, Stefan J., Richardson, Andrea J., Hewitt, Alex W., Vote, Brendan J., Schmied, Denise , Guymer, Robyn H. und Baird, Paul N. (2016) Multiallelic copy number variation in the complement component 4A (C4A) gene is associated with late-stage age-related macular degeneration (AMD). Jornal of Neuroinflammation 13 (81), S. 1-9.

Fritsche, L. G. , Igl, Wilmar, Bailey, J. N., Grassmann, Felix , Sengupta, Sebanti, Bragg-Gresham, Jennifer L., Burdon, Kathryn P., Hebbring, Scott J., Weber, Bernhard H. F. und Heid, Iris M. (2016) A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. Nature Genetics 48, S. 134-143. Volltext nicht vorhanden.

Fleckenstein, Monika , Grassmann, Felix , Lindner, Moritz , Pfau, Maximilian , Czauderna, Joanna, Strunz, Tobias, von Strachwitz, Claudia, Schmitz-Valckenberg, Steffen, Holz, Frank G. und Weber, Bernhard H. F. (2016) Distinct Genetic Risk Profile of the Rapidly Progressing Diffuse-Trickling Subtype of Geographic Atrophy in Age-Related Macular Degeneration (AMD). Investigative Opthalmology & Visual Science 57 (6), S. 2463.

Grassmann, Felix, Ach, Thomas, Brandl, Caroline, Heid, Iris M. und Weber, Bernhard H. F. (2015) What Does Genetics Tell Us About Age-Related Macular Degeneration? Annual Review of Vision Science 1, S. 73-96. Volltext nicht vorhanden.

Weber, Bernhard H. F. , Bergholz, Richard, Mändl, Julia, Jägle, Herbert, Ruether, Klaus und Grassmann, Felix (2015) Common synonymous variants in ABCA4 are protective for chloroquine induced maculopathy (toxic maculopathy). BMC Ophthalmology 15 (18), S. 1-7.

Grassmann, Felix, Friedrich, Ulrike, Fauser, Sascha, Schick, Tina, Milenkovic, Andrea, Schulz, Heidi L., von Strachwitz, Claudia N., Bettecken, Thomas, Lichtner, Peter, Meitinger, Thomas, Arend, Nicole, Wolf, Armin, Haritoglou, Christos, Rudolph, Guenther, Chakravarthy, Usha, Silvestri, Giuliana, McKay, Gareth J., Freitag-Wolf, Sandra, Krawczak, Michael, Smith, R. Theodore, Merriam, John C., Merriam, Joanna E., Allikmets, Rando, Heid, Iris M. und Weber, Bernhard H. F. (2015) A Candidate Gene Association Study Identifies DAPL1 as a Female-Specific Susceptibility Locus for Age-Related Macular Degeneration (AMD). NeuroMolecular Medicine 17 (2), S. 111-120.

Weber, Bernhard H. F. , Grassmann, Felix, Fleckenstein, Monika, Chew, Emily Y., Strunz, Tobias, Schmitz-Valckenberg, Steffen, Göbel, Arno P., Klein, Michael L., Ratnapriya, Rinki , Swaroop, Anand und Holz, Frank G. (2015) Clinical and Genetic Factors Associated with Progression of Geographic Atrophy Lesions in Age-Related Macular Degeneration. PLoS ONE 10 (5), S. 1-13.

Friedrich, Ulrike, Datta, Shyamtanu, Schubert, Thomas, Plößl, Karolina, Schneider, Magdalena, Grassmann, Felix, Fuchshofer, Rudolf, Tiefenbach, Klaus-Jürgen, Längst, Gernot und Weber, Bernhard H. F. (2015) Synonymous variants in HTRA1 implicated in AMD susceptibility impair its capacity to regulate TGF-β signaling. Human Molecular Genetics 24, S. 6361-6373. Volltext nicht vorhanden.

Brandl, Caroline, Grassmann, Felix, Riolfi, Julia und Weber, Bernhard H. F. (2015) Tapping Stem Cells to Target AMD: Challenges and Prospects. Journal of Clinical Medicine 4, S. 282-303.

Grassmann, Felix, Fauser, Sascha und Weber, Bernhard H. F. (2015) The genetics of age-related macular degeneration (AMD) – Novel targets for designing treatment options? European Journal of Pharmaceutics and Biopharmaceutics 95 Part B, S. 194-202. Volltext nicht vorhanden.

Grassmann, Felix, Schoenberger, Peter G. A., Brandl, Caroline, Schick, Tina, Hasler, Daniele, Meister, Gunter, Fleckenstein, Monika, Lindner, Moritz, Helbig, Horst, Fauser, Sascha und Weber, Bernhard H. F. (2014) A circulating microRNA profile is associated with late-stage neovascular age-related macular degeneration. PLoS ONE 9 (9), e107461.

Brandl, Caroline, Zimmermann, Stephanie J., Milenkovic, Vladimir M., Rosendahl, S. M., Grassmann, Felix, Milenkovic, Andrea, Hehr, Ute, Federlin, Marianne, Wetzel, Christian H., Helbig, Horst und Weber, Bernhard H. F. (2014) In-Depth Characterisation of Retinal Pigment Epithelium (RPE) Cells Derived from Human Induced Pluripotent Stem Cells (hiPSC). NeuroMolecular Medicine 16, S. 551-564.

Weber, Bernhard H. F. , Issa, Peter Charbel, Pauly, Diana , Herrmann, Philipp, Grassmann, Felix und Holz, Frank G. (2014) The role of the complement system in age-related macular degeneration. Deutsches Ärzteblatt international 111, S. 133-138. Volltext nicht vorhanden.

Grassmann, Felix, Fritsche, Lars G., Keilhauer, Claudia N., Heid, Iris M. und Weber, Bernhard H. F. (2012) Modelling the Genetic Risk in Age-Related Macular Degeneration. PLoS ONE 7, e37979.

Pürzer, Andreas, Grassmann, Felix, Birzer, Dietmar und Merkl, Rainer (2011) Key2Ann: a tool to process sequence sets by replacing database identifiers with a human-readable annotation. Journal of integrative bioinformatics 8 (1). Volltext nicht vorhanden.

Grassmann, Felix, Heid, Iris M. und Weber, Bernhard H. F. (2014) Genetic risk models in age-related macular degeneration. In: Ash, J. und Grimm, C., (eds.) Retinal Degenerative Diseases. Advances in Experimental Medicine and Biology, 801. Springer, New York, NY, S. 291-300. ISBN 978-1-4614-3209-8 (online), 978-1-4614-3208-1 (print). Volltext nicht vorhanden.