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Anzahl der Einträge: 39.

Artikel

Fiedler, Mathias , Off, Alisa, Gärtner, Andreas, Brockhoff, Gero , Eichberger, Jonas, Gottsauner, Maximilian, Schuderer, Johannes G. , Maurer, Michael , Bauer, Richard J. , Gerken, Michael, Reichert, Torsten E., Ettl, Tobias und Weber, Florian (2024) Increased PD‐1/PD‐L1 Immune Checkpoint Expression Is Associated With Oral Squamous Cell Carcinoma in Never‐Smokers and Never‐Drinkers. Head & Neck.

Albert, Veruschka, Bruss, Christina, Tümen, Deniz, Piendl, Gerhard, Weber, Florian , Dahl, Edgar, Seitz, Stephan, Ortmann, Olaf , Wege, Anja K. und Brockhoff, Gero (2024) HER4 Affects Sensitivity to Tamoxifen and Abemaciclib in Luminal Breast Cancer Cells and Restricts Tumor Growth in MCF-7-Based Humanized Tumor Mice. International Journal of Molecular Sciences 25 (13), S. 7475.

Bruss, Christina, Albert, Veruschka, Seitz, Stephan, Blaimer, Stephanie , Kellner, Kerstin, Pohl, Fabian, Ortmann, Olaf , Brockhoff, Gero und Wege, Anja K. (2024) Neoadjuvant radiotherapy in ER+, HER2+, and triple-negative -specific breast cancer based humanized tumor mice enhances anti-PD-L1 treatment efficacy. Frontiers in Immunology 15.

Schulz, Daniela , Feulner, Laura, Rubenich, Dominique S. , Heimer, Sina, Rohrmüller, Sophia, Reinders, Yvonne, Falchetti, Marcelo, Wetzel, Martin, Braganhol, Elizandra , Lummertz da Rocha, Edroaldo, Schäfer, Nicole, Stöckl, Sabine, Brockhoff, Gero , Wege, Anja K. , Fritsch, Jürgen , Pohl, Fabian, Reichert, Torsten E., Ettl, Tobias und Bauer, Richard J. (2023) Subcellular localization of PD‐L1 and cell‐cycle‐dependent expression of nuclear PD‐L1 variants: implications for head and neck cancer cell functions and therapeutic efficacy. Molecular Oncology.

Brockhoff, Gero (2023) Complementary Tumor Diagnosis by Single Cell–Based Cytogenetics Using Multi‐marker Fluorescence In Situ Hybridization (mFISH). Current Protocols 3 (11).

Bruss, Christina, Kellner, Kerstin, Albert, Veruschka, Hutchinson, James A. , Seitz, Stephan, Ortmann, Olaf , Brockhoff, Gero und Wege, Anja K. (2023) Immune Checkpoint Profiling in Humanized Breast Cancer Mice Revealed Cell-Specific LAG-3/PD-1/TIM-3 Co-Expression and Elevated PD-1/TIM-3 Secretion. Cancers 15 (9), S. 2615.

Brockhoff, Gero (2022) “Shedding” light on HER4 signaling in normal and malignant breast tissues. Cellular Signalling 97.

Bruss, Christina, Kellner, Kerstin, Ortmann, Olaf , Seitz, Stephan, Brockhoff, Gero , Hutchinson, James A. und Wege, Anja Kathrin (2022) Advanced Immune Cell Profiling by Multiparameter Flow Cytometry in Humanized Patient-Derived Tumor Mice. Cancers 14 (9), S. 2214.

Albert, Veruschka, Piendl, Gerhard, Yousseff, Dali, Lammert, Hedwig, Hummel, Michael, Ortmann, Olaf , Jagla, Wolfgang, Gaumann, Andreas, Wege, Anja K. und Brockhoff, Gero (2022) Protein kinase C targeting of luminal (T-47D), luminal/HER2-positive (BT474), and triple negative (HCC1806) breast cancer cells in-vitro with AEB071 (Sotrastaurin) is efficient but mediated by subtype specific molecular effects. Archives of Gynecology and Obstetrics.

Wege, Anja Kathrin, Rom‐Jurek, Eva‐Maria, Jank, Paul, Denkert, Carsten, Ugocsai, Peter, Solbach, Christine, Blohmer, Jens‐Uwe, Sinn, Bruno, Mackelenbergh, Marion, Möbus, Volker, Trumpp, Andreas, Marangoni, Elisabetta, Pfarr, Nicole, Irlbeck, Christoph , Warfsmann, Jens, Polzer, Bernhard , Weber, Florian, Ortmann, Olaf , Loibl, Sibylle, Vladimirova, Valentina und Brockhoff, Gero (2021) mdm2 gene amplification is associated with luminal breast cancer progression in humanized PDX mice and a worse outcome of estrogen receptor positive disease. International Journal of Cancer 150, S. 1357-1372.

Schulz, Daniela, Wetzel, Martin, Eichberger, Jonas, Piendl, Gerhard, Brockhoff, Gero , Wege, Anja K. , Reichert, Torsten, Ettl, Tobias und Bauer, Richard J. (2021) Differential Expression of PD-L1 during Cell Cycle Progression of Head and Neck Squamous Cell Carcinoma. International Journal of Molecular Sciences 22 (23), S. 1-18.

Wege, Anja Kathrin , Dreyer, Tobias F., Teoman, Attila, Ortmann, Olaf , Brockhoff, Gero und Bronger, Holger (2021) CX3CL1 Overexpression Prevents the Formation of Lung Metastases in Trastuzumab-Treated MDA-MB-453-Based Humanized Tumor Mice (HTM). Cancers 2021 (13), S. 2459. (Eingereicht)

Wege, Anja Kathrin, Dreyer, Tobias F., Teoman, Attila, Ortmann, Olaf, Brockhoff, Gero und Bronger, Holger (2021) CX3CL1 Overexpression Prevents the Formation of Lung Metastases in Trastuzumab-Treated MDA-MB-453-Based Humanized Tumor Mice (HTM). Cancers 13 (10), S. 2459. Volltext nicht vorhanden.

Wege, Anja K., Kirchhammer, Nicole, Kazandjian, Linda Veronique, Prassl, Sandra, Brandt, Michael, Piendl, Gerhard, Ortmann, Olaf , Fischer, Stephan und Brockhoff, Gero (2020) A novel rabbit derived anti-HER2 antibody with pronounced therapeutic effectiveness on HER2-positive breast cancer cells in vitro and in humanized tumor mice (HTM). Journal of Translational Medicine 18, S. 316.

Fiedler, Mathias, Schulz, Daniela , Piendl, Gerhard, Brockhoff, Gero , Eichberger, Jonas, Menevse, Ayse N., Beckhove, Philipp , Hautmann, Matthias G. , Reichert, Torsten E., Ettl, Tobias und Bauer, Richard J. (2020) Buparlisib modulates PD-L1 expression in head and neck squamous cell carcinoma cell lines. Experimental Cell Research 396 (1), S. 112259. Volltext nicht vorhanden.

Schulz, Daniela , Streller, Melanie, Piendl, Gerhard, Brockhoff, Gero , Reichert, Torsten E., Menevse, Ayse N., Beckhove, Philipp , Hautmann, Matthias G. , Bauer, Richard J. und Ettl, Tobias (2019) Differential localization of PD-L1 and Akt-1 involvement in radioresistant and radiosensitive cell lines of head and neck squamous cell carcinoma. Carcinogenesis 41 (7), S. 984-992. Volltext nicht vorhanden.

Schulz, Daniela , Stancev, Irene, Sorrentino, Antonio, Menevse, Ayse N., Beckhove, Philipp , Brockhoff, Gero , Hautmann, Matthias G. , Reichert, Torsten E., Bauer, Richard J. und Ettl, Tobias (2019) Increased PD-L1 expression in radioresistant HNSCC cell lines after irradiation affects cell proliferation due to inactivation of GSK-3beta. Oncotarget 10 (5), S. 573-583.

Wege, Anja Kathrin, Chittka, Dominik, Buchholz, Stefan, Klinkhammer-Schalke, Monika, Diermeier-Daucher, Simone, Zeman, Florian, Ortmann, Olaf und Brockhoff, Gero (2018) HER4 expression in estrogen receptor-positive breast cancer is associated with decreased sensitivity to tamoxifen treatment and reduced overall survival of postmenopausal women. Breast Cancer Research 20 (1), S. 1-15.

Rom-Jurek, Eva-Maria , Kirchhammer, Nicole, Ugocsai, Peter, Ortmann, Olaf, Wege, Anja und Brockhoff, Gero (2018) Regulation of Programmed Death Ligand 1 (PD-L1) Expression in Breast Cancer Cell Lines In Vitro and in Immunodeficient and Humanized Tumor Mice. International Journal of Molecular Sciences 19 (2), S. 563.

Brockhoff, Gero, Seitz, Stephan, Weber, Florian, Zeman, Florian, Klinkhammer-Schalke, Monika, Ortmann, Olaf und Wege, Anja Kathrin (2018) The presence of PD-1 positive tumor infiltrating lymphocytes in triple negative breast cancers is associated with a favorable outcome of disease. Oncotarget 2018 (9), S. 6201-6212.

Reinders, Yvonne, Felthaus, Oliver, Brockhoff, Gero, Pohl, Fabian, Ahrens, Norbert , Prantl, Lukas und Haubner, Frank (2017) Impact of Platelet-Rich Plasma on Viability and Proliferation in Wound Healing Processes after External Radiation. International Journal of Molecular Sciences 18 (8), S. 1819.

Hoffmann, Martin, Pasch, Sophie, Schamberger, Thomas, Maneck, Matthias, Möhlendick, Birte, Schumacher, Sarah, Brockhoff, Gero, Knoefel, Wolfram Trudo, Izbicki, Jakob, Polzer, Bernhard, Stoecklein, Nikolas H. und Klein, Christoph A. (2017) Diagnostic pathology of early systemic cancer:ERBB2gene amplification in single disseminated cancer cells determines patient survival in operable esophageal cancer. International Journal of Cancer 142 (4), S. 833-843. Volltext nicht vorhanden.

Holzschuh, Maria-Anna, Czyz, Zbigniew, Hauke, Sven, Inwald, Elisabeth C., Polzer, Bernhard und Brockhoff, Gero (2017) HER2 FISH results in breast cancers with increased CEN17 signals using alternative chromosome 17 probes - reclassifying cases in the equivocal category. Histopathology 71 (4), S. 610-625. Volltext nicht vorhanden.

Hilber, Franz, Loibl, Markus , Lang, Siegmund, Kerschbaum, Maximilian, Brockhoff, Gero, Angele, Peter, Zellner, Johannes, Schmitz, Paul, Nerlich, Michael und Worlicek, Michael (2017) Leukocyte-reduced platelet-rich plasma increases proliferation of tenocytes treated with prednisolone: a cell cycle analysis. Archives of Orthopaedic and Trauma Surgery 137 (10), S. 1417-1422. Volltext nicht vorhanden.

Lang, Siegmund, Herrmann, Marietta, Pfeifer, Christian, Brockhoff, Gero, Zellner, Johannes, Nerlich, Michael, Angele, Peter, Prantl, Lukas, Gehmert, Sebastian und Loibl, Markus (2017) Leukocyte-reduced platelet-rich plasma stimulates the in vitro proliferation of adipose-tissue derived mesenchymal stem cells depending on PDGF signaling. Clinical Hemorheology and Microcirculation 67 (2), S. 183-196. Volltext nicht vorhanden.

Hanke, Alexander, Prantl, Lukas, Wenzel, Carina, Nerlich, Michael, Brockhoff, Gero, Loibl, Markus , Gehmert, Sebastian , Jung, F. und Gori, T. (2017) Semi-automated extraction and characterization of Stromal Vascular Fraction using a new medical device. Clinical Hemorheology and Microcirculation 64 (3), S. 403-412. Volltext nicht vorhanden.

Wege, Anja K., Weber, Florian, Kroemer, Alexander, Ortmann, Olaf, Nimmerjahn, Falk und Brockhoff, Gero (2016) IL-15 enhances the anti-tumor activity of trastuzumab against breast cancer cells but causes fatal side effects in humanized tumor mice (HTM). Oncotarget 8 (2), S. 2731-2744.

Loibl, Markus , Lang, Siegmund, Hanke, Alexander, Herrmann, Marietta, Huber, Michaela, Brockhoff, Gero, Klein, Silvan, Nerlich, Michael, Angele, Peter, Prantl, Lukas und Gehmert, Sebastian (2016) Leukocyte-Reduced Platelet-Rich Plasma Alters Protein Expression of Adipose Tissue–Derived Mesenchymal Stem Cells. Plastic and Reconstructive Surgery 138 (2), S. 397-408. Volltext nicht vorhanden.

Brockhoff, Gero, Bock, Maria, Zeman, Florian und Hauke, Sven (2016) The FlexISH assay brings flexibility to cytogeneticHER2testing. Histopathology 69 (4), S. 635-646. Volltext nicht vorhanden.

Loibl, Markus , Lang, Siegmund, Brockhoff, Gero, Gueorguiev, Boyko, Hilber, Franz, Worlicek, Michael, Baumann, Florian, Grechenig, Stephan, Zellner, Johannes, Huber, Michaela, Valderrabano, Victor, Angele, Peter, Nerlich, Michael, Prantl, Lukas und Gehmert, Sebastian (2016) The effect of leukocyte-reduced platelet-rich plasma on the proliferation of autologous adipose-tissue derived mesenchymal stem cells1. Clinical Hemorheology and Microcirculation 61 (4), S. 599-614. Volltext nicht vorhanden.

Ach, Tobias, Schwarz-Furlan, Stephan, Ach, Stephanie, Agaimy, Abbas, Gerken, Michael, Rohrmeier, Christian, Zenk, Johannes, Iro, Heinrich, Brockhoff, Gero und Ettl, Tobias (2015) Genomic aberrations of MDM2, MDM4, FGFR1 and FGFR3 are associated with poor outcome in patients with salivary gland cancer. Journal of Oral Pathology & Medicine 45 (7), S. 500-509. Volltext nicht vorhanden.

Huber, Stefan, Wege, Anja K., Bernhardt, Günther, Buschauer, Armin und Brockhoff, Gero (2015) Topotecan-induced ABCG2 expression in MCF-7 cells is associated with decreased CD24 and EpCAM expression and a loss of tumorigenicity. Cytometry A 87 (8), S. 707-716. Volltext nicht vorhanden.

Gehmert, Sebastian, Wenzel, Carina, Loibl, Markus, Brockhoff, Gero, Huber, Michaela, Krutsch, Werner, Nerlich, Michael, Gosau, Martin, Klein, Silvan, Schreml, Stephan, Prantl, Lukas und Gehmert, Sanga (2014) Adipose tissue-derived Stem Cell (ASC) secreted IGF-1 protects myoblasts from the negative effect of Myostatin. BioMed Research International 2014.

Machleidt, Anna, Buchholz, Stefan, Diermeier-Daucher, S., Zeman, Florian, Ortmann, Olaf und Brockhoff, Gero (2013) The prognostic value of Her4 receptor isoform expression in triple-negative and Her2 positive breast cancer patients. BMC Cancer 13.

Heller, Anne, Brockhoff, Gero und Goepferich, Achim (2012) Targeting drugs to mitochondria. European Journal of Pharmaceutics and Biopharmaceutics 82, S. 1-18. Volltext nicht vorhanden.

Plander, Mark, Ugocsai, Peter, Seegers, Silvia, Orso, Evelyn, Reichle, Albrecht, Schmitz, Gerd, Hofstädter, Ferdinand und Brockhoff, Gero (2011) Chronic lymphocytic leukemia cells induce anti-apoptotic effects of bone marrow stroma. Annals of Hematology. Volltext nicht vorhanden.

Sassen, Andrea, Rochon, Justine, Wild, Peter, Hartmann, Arndt, Hofstädter, Ferdinand, Schwarz, Stephan und Brockhoff, Gero (2008) Cytogenetic analysis of HER1 / EGFR, HER2, HER3 and HER4 in 278 breast cancer patients. Breast cancer research. Volltext nicht vorhanden.

Vollmann, Arabel, Vornlocher, Hans-Peter, Stempfl, Thomas, Brockhoff, Gero, Apfel, Rainer und Bogdahn, Ulrich (2006) Effective silencing of EGFR with RNAi demonstrates non-EGFR dependent proliferation of glioma cells. International journal of oncology 28 (6), S. 1531-1542. Zugang zum Volltext eingeschränkt.

Ewing, Patricia, Wilke, Andrea, Brockhoff, Gero, Andreesen, Reinhard, Eissner, Günther, Holler, Ernst und Gerbitz, Armin (2003) Isolation and transplantation of allogeneic pulmonary endothelium derived from GFP transgenic mice. Journal of immunological methods 283 (1-2), S. 307-15. Volltext nicht vorhanden.

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