Entries of Elz, Sigurd on the publication server
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Number of items: 64.
2025
Sellmer, Andreas, Able, Marina, Spiekermann, Karsten, Reinecke, Maria, Kuster, Bernhard, Utpatel, Kirsten
, Wirth, Lukas, Pongratz, Herwig, Plank, Nicole, Koch, Pierre
, Elz, Sigurd, Fischer, Amrei, Tizazu, Belay, Fiebig, Heinz-Herbert, Dove, Stefan and Mahboobi, Siavosh
(2025)
Novel water-soluble and highly efficient dual type I/II next generation inhibitors of FMS-like tyrosine kinase 3 (FLT3).
European Journal of Medicinal Chemistry 296, p. 117849.
2021
Szczepańska, Katarzyna
, Pockes, Steffen
, Podlewska, Sabina, Höring, Carina, Mika, Kamil, Latacz, Gniewomir, Bednarski, Marek, Siwek, Agata
, Karcz, Tadeusz, Nagl, Martin, Bresinsky, Merlin, Mönnich, Denise, Seibel, Ulla, Kuder, Kamil J.
, Kotańska, Magdalena, Stark, Holger, Elz, Sigurd and Kieć-Kononowicz, Katarzyna
(2021)
Structural modifications in the distal, regulatory region of histamine H3 receptor antagonists leading to the identification of a potent anti-obesity agent.
European Journal of Medicinal Chemistry 213, p. 113041.
Fulltext not available.
, Pockes, Steffen
, Podlewska, Sabina, Höring, Carina, Mika, Kamil, Latacz, Gniewomir, Bednarski, Marek, Siwek, Agata
, Karcz, Tadeusz, Nagl, Martin, Bresinsky, Merlin, Mönnich, Denise, Seibel, Ulla, Kuder, Kamil J.
, Kotańska, Magdalena, Stark, Holger, Elz, Sigurd and Kieć-Kononowicz, Katarzyna
(2021)
Structural modifications in the distal, regulatory region of histamine H3 receptor antagonists leading to the identification of a potent anti-obesity agent.
European Journal of Medicinal Chemistry 213, p. 113041.
Fulltext not available.
2020
Sellmer, Andreas, Pilsl, Bernadette, Beyer, Mandy, Pongratz, Herwig, Wirth, Lukas, Elz, Sigurd, Dove, Stefan, Henninger, Sven Julian, Spiekermann, Karsten, Polzer, Harald, Klaeger, Susan, Kuster, Bernhard, Böhmer, Frank D., Fiebig, Heinz-Herbert, Krämer, Oliver H. and Mahboobi, Siavosh
(2020)
A series of novel aryl-methanone derivatives as inhibitors of FMS-like tyrosine kinase 3 (FLT3) in FLT3-ITD-positive acute myeloid leukemia.
European Journal of Medicinal Chemistry 193, p. 112232.
Fulltext not available.
2019
Pockes, Steffen, Wifling, David
, Buschauer, Armin
and Elz, Sigurd
(2019)
Structure‐Activity Relationship of Hetarylpropylguanidines Aiming at the Development of Selective Histamine Receptor Ligands †.
ChemistryOpen 8 (3), pp. 285-297.
2018
Pockes, Steffen
, Wifling, David
, Keller, Max, Buschauer, Armin
and Elz, Sigurd
(2018)
Highly Potent, Stable, and Selective Dimeric Hetarylpropylguanidine-Type Histamine H2 Receptor Agonists.
ACS Omega 2018 (3), pp. 2865-2882.
Leonhardt, Michel, Sellmer, Andreas
, Krämer, Oliver H., Dove, Stefan, Elz, Sigurd, Kraus, Birgit, Beyer, Mandy and Mahboobi, Siavosh
(2018)
Design and biological evaluation of tetrahydro-β-carboline derivatives as highly potent histone deacetylase 6 (HDAC6) inhibitors.
European Journal of Medicinal Chemistry 152, pp. 329-357.
Fulltext not available.
, Krämer, Oliver H., Dove, Stefan, Elz, Sigurd, Kraus, Birgit, Beyer, Mandy and Mahboobi, Siavosh
(2018)
Design and biological evaluation of tetrahydro-β-carboline derivatives as highly potent histone deacetylase 6 (HDAC6) inhibitors.
European Journal of Medicinal Chemistry 152, pp. 329-357.
Fulltext not available.
Sellmer, Andreas, Stangl, Hubert, Beyer, Mandy, Grünstein, Elisabeth, Leonhardt, Michel, Pongratz, Herwig, Eichhorn, Emerich, Elz, Sigurd, Striegl, Birgit, Jenei-Lanzl, Zsuzsa, Dove, Stefan, Straub, Rainer H., Krämer, Oliver H. and Mahboobi, Siavosh
(2018)
Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors.
Journal of Medicinal Chemistry 61 (8), pp. 3454-3477.
Fulltext not available.
2016
Lieb, Sebastian, Littmann, Timo, Plank, Nicole, Felixberger, Johannes, Tanaka, Miho, Schäfer, Thorsten, Krief, Stéphane, Elz, Sigurd, Friedland, Kristina, Bernhardt, Günther, Wegener, Joachim, Ozawa, Takeaki and Buschauer, Armin
(2016)
Label-free versus conventional cellular assays: functional investigations on the human histamine H1 receptor.
Pharmacological Research 114, pp. 13-26.
Fulltext not available.
Naporra, Franziska, Gobleder, Susanne, Wittmann, Hans-Joachim, Spindler, Julia, Bodensteiner, Michael, Bernhardt, Günther, Hübner, Harald, Gmeiner, Peter, Elz, Sigurd and Strasser, Andrea
(2016)
Dibenzo[b,f][1,4]oxazepines and dibenzo[b,e]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H1R, H4R, 5-HT2AR and other selected GPCRs.
Pharmacological Research 113, pp. 610-625.
(In Press)
Fulltext not available.
Hammer, Sebastian, Gobleder, Susanne, Naporra, Franziska, Wittmann, Hans-Joachim, Elz, Sigurd, Heinrich, Markus
and Strasser, Andrea
(2016)
2,4-Diaminopyrimidines as dual ligands at the histamine H1 and H4 receptor - H1/H4-receptor selectivity.
Bioorganic & Medicinal Chemistry Letters 26, pp. 292-300.
Fulltext not available.
and Strasser, Andrea
(2016)
2,4-Diaminopyrimidines as dual ligands at the histamine H1 and H4 receptor - H1/H4-receptor selectivity.
Bioorganic & Medicinal Chemistry Letters 26, pp. 292-300.
Fulltext not available.
Naporra, Franziska, Gobleder, Susanne, Wittmann, Hans-Joachim, Spindler, Julia, Bodensteiner, Michael, Bernhardt, Günther, Hübner, Harald, Gmeiner, Peter
, Elz, Sigurd and Strasser, Andrea
(2016)
Dibenzo[ b , f ][1,4]oxazepines and dibenzo[ b , e ]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H 1 R, H 4 R, 5-HT 2A R and other selected GPCRs.
Pharmacological Research 113, pp. 610-625.
Fulltext not available.
, Elz, Sigurd and Strasser, Andrea
(2016)
Dibenzo[ b , f ][1,4]oxazepines and dibenzo[ b , e ]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H 1 R, H 4 R, 5-HT 2A R and other selected GPCRs.
Pharmacological Research 113, pp. 610-625.
Fulltext not available.
2015
Baumeister, Paul, Erdmann, Daniela, Biselli, Sabrina, Kagermeier, Nicole, Elz, Sigurd, Bernhardt, Günther and Buschauer, Armin
(2015)
3HUR-DE257: Development of a tritium-labeled squaramide-type selective histamine H2 receptor antagonist.
ChemMedChem 10 (1), pp. 83-93.
Fulltext not available.
2014
Wager, Eva, Wittmann, Hans-Joachim, Elz, Sigurd and Strasser, Andrea
(2014)
Pharmacological profile of astemizole-derived compounds at the histamine H1 and H4 receptor - H1/H4 receptor selectivity.
Naunyn-Schmiedeberg's Archives of Pharmacology 387, pp. 235-250.
Fulltext not available.
Geyer, Roland, Igel, Patrick, Kaske, Melanie, Elz, Sigurd and Buschauer, Armin
(2014)
Synthesis, SAR and selectivity of 2-acyl- and 2-cyano-1-hetarylalkyl-guanidines at the four histamine receptor subtypes: a bioisosteric approach.
MedChemComm 5 (1), pp. 72-81.
Fulltext not available.
2013
Sadek, Bassem, Alisch, Rudi, Buschauer, Armin and Elz, Sigurd
(2013)
Synthesis and dual histamine H1 and H2 receptor antagonist activity of cyanoguanidine derivatives.
Molecules 18 (11), pp. 14186-14202.
2012
Birnkammer, Tobias, Spickenreither, Anja, Brunskole, Irena, Lopuch, Miroslaw, Kagermeier, Nicole, Bernhardt, Günther, Dove, Stefan, Seifert, Roland, Elz, Sigurd and Buschauer, Armin
(2012)
The bivalent ligand approach leads to highly potent and selective acylguanidine-type histamine H2 receptor agonists.
Journal of Medicinal Chemistry 55 (3), pp. 1147-1160.
Fulltext not available.
2011
Silva, Maria Elena, Heim, Ralf, Strasser, Andrea, Elz, Sigurd and Dove, Stefan
(2011)
Theoretical studies on the interaction of partial agonists with the 5-HT(2A) receptor.
Journal of computer-aided molecular design 25 (1), pp. 51-66.
Fulltext not available.
Pertz, Heinz, Lehmann, Jochen, Roth-Ehrang, René and Elz, Sigurd
(2011)
Effects of Ginger Constituents on the Gastrointestinal Tract: Role of Cholinergic M3and Serotonergic 5-HT3and 5-HT4Receptors.
Planta Medica 77 (10), pp. 973-978.
Fulltext not available.
Wagner, Eva, Wittmann, Hans-Joachim, Elz, Sigurd and Strasser, Andrea
(2011)
Mepyramine-JNJ7777120-hybrid compounds show high affinity to hH1R, but low affinity to hH4R.
Bioorganic & Medicinal Chemistry Letters 21, pp. 6274-9280.
Fulltext not available.
Wittmann, Hans-Joachim, Elz, Sigurd, Seifert, Roland and Strasser, Andrea
(2011)
Na-methylated phenylhistamines exhibit affinity to the hH4R - a pharmacological and molecular modelling study.
Naunyn Schmiedeberg's Arch Pharmacol 384, pp. 287-299.
Fulltext not available.
2010
Ghorai, Prasanta, Kraus, Anja, Birnkammer, Tobias, Geyer, Roland, Bernhardt, Günther, Dove, Stefan, Seifert, Roland, Elz, Sigurd and Buschauer, Armin
(2010)
Chiral N(G)-acylated hetarylpropylguanidine-type histamine H2 receptor agonists do not show significant stereoselectivity.
Bioorganic & Medicinal Chemistry Letters 20 (10), pp. 3173-3176.
Fulltext not available.
2009
Igel, Patrick, Schneider, Erich
, Schnell, David, Elz, Sigurd, Seifert, Roland and Buschauer, Armin
(2009)
N(G)-Acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent.
Journal of Medicinal Chemistry 52 (8), pp. 2623-2627.
Fulltext not available.
, Schnell, David, Elz, Sigurd, Seifert, Roland and Buschauer, Armin
(2009)
N(G)-Acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent.
Journal of Medicinal Chemistry 52 (8), pp. 2623-2627.
Fulltext not available.
Kraus, Anja, Ghorai, Prasanta, Birnkammer, Tobias, Schnell, David, Elz, Sigurd, Seifert, Roland, Dove, Stefan, Bernhardt, Günther and Buschauer, Armin
(2009)
N(G)-Acylated aminothiazolylpropylguanidines as potent and selective histamine H2 receptor agonists.
ChemMedChem 4 (2), pp. 232-240.
Fulltext not available.
Strasser, Andrea, Wittmann, Hans-Joachim, Kunze, Marc, Elz, Sigurd and Seifert, Roland
(2009)
Molecular basis for the selective interaction of synthetic agonists with the human histamine H1-receptor compared with the guinea-pig H1-receptor.
Mol Pharmacol : Molecular pharmacology 75, pp. 454-465.
Fulltext not available.
2008
Ghorai, Prasanta, Kraus, Anja, Keller, Max, Götte, Carsten, Igel, Patrick, Schneider, Erich
, Schnell, David, Bernhardt, Günther, Dove, Stefan, Zabel, Manfred, Elz, Sigurd, Seifert, Roland and Buschauer, Armin
(2008)
Acylguanidines as bioisosteres of guanidines: N(G)-acylated imidazolylpropylguanidines, a new class of histamine H2 receptor agonists.
Journal of Medicinal Chemistry 51 (22), pp. 7193-7204.
Fulltext not available.
, Schnell, David, Bernhardt, Günther, Dove, Stefan, Zabel, Manfred, Elz, Sigurd, Seifert, Roland and Buschauer, Armin
(2008)
Acylguanidines as bioisosteres of guanidines: N(G)-acylated imidazolylpropylguanidines, a new class of histamine H2 receptor agonists.
Journal of Medicinal Chemistry 51 (22), pp. 7193-7204.
Fulltext not available.
Dove, Stefan, Seifert, Roland, Elz, Sigurd and Buschauer, Armin
(2008)
Frontiers in medicinal chemistry in Regensburg.
ChemMedChem 3 (8), pp. 1181-1184.
Fulltext not available.
Mahboobi, Siavosh, Sellmer, Andreas, Eswayah, Asma, Elz, Sigurd, Uecker, Andrea and Böhmer, Frank-D.
(2008)
Inhibition of PDGFR tyrosine kinase activity by a series of novel N-(3-(4-(pyridin-3-yl)-1H-imidazol-2-ylamino)phenyl)amides: a SAR study on the bioisosterism of pyrimidine and imidazole.
European journal of medicinal chemistry 43 (7), pp. 1444-1453.
Fulltext not available.
2007
Mahboobi, Siavosh, Uecker, A., Cénac, C., Sellmer, A., Eichhorn, E., Elz, Sigurd, Böhmer, F.-D. and Dove, Stefan
(2007)
Inhibition of FLT3 and PDGFR tyrosine kinase activity by bis(benzo[b]furan-2-yl)methanones.
Bioorganic & medicinal chemistry 15 (5), pp. 2187-2197.
Fulltext not available.
Mahboobi, Siavosh, Uecker, Andrea, Cénac, Christophe, Sellmer, Andreas, Eichhorn, Emerich, Elz, Sigurd, Böhmer, Frank-D. and Dove, Stefan
(2007)
Inhibition of FLT3 and PDGFR tyrosine kinase activity by bis(benzo[b]furan-2-yl)methanones.
Bioorganic & Medicinal Chemistry 15 (5), pp. 2187-2197.
Fulltext not available.
2006
Xie, Sheng-Xue, Kraus, Anja, Ghorai, Prasanta, Ye, Qi-Zhuang, Elz, Sigurd, Buschauer, Armin and Seifert, Roland
(2006)
N1-(3-Cyclohexylbutanoyl)-N2-[3-(1H-imidazol-4-
yl)propyl]guanidine (UR-AK57), a Potent Partial Agonist for the Human Histamine H1- and H2- Receptors. Journal of Pharmacology and Experimental Therapeutics 317 (3), pp. 1262-1268. Fulltext restricted.
yl)propyl]guanidine (UR-AK57), a Potent Partial Agonist for the Human Histamine H1- and H2- Receptors. Journal of Pharmacology and Experimental Therapeutics 317 (3), pp. 1262-1268. Fulltext restricted.
Patil, Rameshwar, Elz, Sigurd and Reiser, Oliver
(2006)
Side-chain modified analogues of histaprodifen: Asymmetric synthesis and histamine H₁-receptor activity.
Bioorg. Med. Chem. Lett. 16 (3), pp. 672-676.
Fulltext not available.
(2006)
Side-chain modified analogues of histaprodifen: Asymmetric synthesis and histamine H₁-receptor activity.
Bioorg. Med. Chem. Lett. 16 (3), pp. 672-676.
Fulltext not available.
Mahboobi, Siavosh, Eichhorn, Emerich, Popp, Alfred, Sellmer, Andreas, Elz, Sigurd and Möllmann, Ute
(2006)
3-Bromo-4-(1H-3-indolyl)-2,5-dihydro-1H-2,5-pyrroledione derivatives as new lead compounds for antibacterially active substances.
European Journal of Medicinal Chemistry 41 (2), pp. 176-191.
Fulltext not available.
Mahboobi, Siavosh, Uecker, Andrea, Sellmer, Andreas, Cénac, Christophe, Höcher, Heymo, Pongratz, Herwig, Eichhorn, Emerich, Hufsky, Harald, Trümpler, Antje, Sicker, Marit, Heidel, Florian, Fischer, Thomas, Stocking, Carol, Elz, Sigurd, Böhmer, Frank-D. and Dove, Stefan
(2006)
Novel Bis(1H-indol-2-yl)methanones as Potent Inhibitors of FLT3 and Platelet-Derived Growth Factor Receptor Tyrosine Kinase.
Journal of Medicinal Chemistry 49 (11), pp. 3101-3115.
Fulltext not available.
Mahboobi, Siavosh, Uecker, A., Sellmer, A., Cénac, C., Höcher, H., Pongratz, H., Hufsky, H., Trümpler, A., Sicker, M., Heidel, F., Fischer, T., Stocking, C., Elz, Sigurd, Böhmer, F.-D. and Dove, Stefan
(2006)
Novel bis-(1H-indol-2-yl)-methanones as potent inhibitors of FLT3 and platelet-derived growth factor receptor tyrosine kinase.
Journal of Medicinal Chemistry 49 (11), pp. 3101-3115.
Fulltext not available.
2004
Pertz, Heinz, Elz, Sigurd and Schunack, Walter
(2004)
Structure-Activity Relationships of Histamine H1-Receptor Agonists.
Mini-Reviews in Medicinal Chemistry 4 (9), pp. 935-940.
Fulltext not available.
Dove, Stefan, Elz, Sigurd, Seifert, Roland and Buschauer, Armin
(2004)
Structure-Activity Relationships of Histamine H2 Receptor Ligands+.
Mini-Reviews in Medicinal Chemistry 4 (9), pp. 941-954.
Fulltext not available.
Dove, Stefan, Elz, Sigurd, Seifert, Roland and Buschauer, Armin
(2004)
Structure-Activity Relationships of Histamine H_2 Receptor Ligands,.
Mini-Rev. Med. Chem. 4 (9), pp. 941-954.
Fulltext not available.
2003
Li, Liantao, Kracht, Julia, Peng, Shiqi, Bernhardt, Günther, Elz, Sigurd and Buschauer, Armin
(2003)
Synthesis and pharmacological activity of fluorescent histamine H2 receptor antagonists related to potentidine,.
Bioorganic & Medicinal Chemistry Letters 13 (10), 0960-894.
Fulltext not available.
Seifert, Roland, Wenzel-Seifert, Katharina, Bürckstümmer, Tilmann, Pertz, Heinz H., Schunack, Walter, Dove, Stefan, Buschauer, Armin and Elz, Sigurd
(2003)
Multiple differences in agonist and antagonist pharmacology between human and guinea pig histamine H1-receptor,.
Journal of Pharmacology and Experimental Therapeutics 305, pp. 1104-1115.
Fulltext not available.
Menghin, Sonja, Pertz, Heinz H., Kramer, Kai, Seifert, Roland, Schunack, Walter and Elz, Sigurd
(2003)
Nα-Imidazolylalkyl and Pyridylalkyl Derivatives of Histaprodifen: Synthesis and in Vitro Evaluation of Highly Potent Histamine H1-Receptor Agonists.
Journal of Medicinal Chemistry 46 (25), pp. 5458-5470.
Fulltext not available.
Govoni, Marinella, Bakker, Remko A., van de Wetering, Ineke, Smit, Martine J., Menge, Wiro M. B. P., Timmerman, Henk, Elz, Sigurd, Schunack, Walter and Leurs, Rob
(2003)
Synthesis and Pharmacological Identification of Neutral Histamine H1-Receptor Antagonists.
Journal of Medicinal Chemistry 46 (26), pp. 5812-5824.
Fulltext not available.
2002
El-Subbagh, Hussein, Wittig, Thomas, Decker, Michael, Elz, Sigurd, Nieger, Martin
and Lehmann, Jochen
(2002)
Dopamine/Serotonin Receptor Ligands. Part IV [1]: Synthesis and Pharmacology of Novel 3-Benzazecines and 3-Benzazonines as Potential 5-HT2A and Dopamine Receptor Ligands.
Archiv der Pharmazie 335 (9), pp. 443-448.
Fulltext not available.
and Lehmann, Jochen
(2002)
Dopamine/Serotonin Receptor Ligands. Part IV [1]: Synthesis and Pharmacology of Novel 3-Benzazecines and 3-Benzazonines as Potential 5-HT2A and Dopamine Receptor Ligands.
Archiv der Pharmazie 335 (9), pp. 443-448.
Fulltext not available.
Sasse, Astrid
, Ligneau, Xavier, Rouleau, Agnès, Elz, Sigurd, Ganellin, C. Robin, Arrang, Jean-Michel, Schwartz, Jean-Charles, Schunack, Walter and Stark, Holger
(2002)
Influence of Bulky Substituents on Histamine H3Receptor Agonist/Antagonist Properties.
Journal of Medicinal Chemistry 45 (18), pp. 4000-4010.
Fulltext not available.
, Ligneau, Xavier, Rouleau, Agnès, Elz, Sigurd, Ganellin, C. Robin, Arrang, Jean-Michel, Schwartz, Jean-Charles, Schunack, Walter and Stark, Holger
(2002)
Influence of Bulky Substituents on Histamine H3Receptor Agonist/Antagonist Properties.
Journal of Medicinal Chemistry 45 (18), pp. 4000-4010.
Fulltext not available.
Graßmann, Sven, Sadek, Bassem, Ligneau, Xavier, Elz, Sigurd, Ganellin, C.Robin, Arrang, Jean-Michel, Schwartz, Jean-Charles, Stark, Holger
and Schunack, Walter
(2002)
Progress in the proxifan class: heterocyclic congeners as novel potent and selective histamine H3-receptor antagonists.
European Journal of Pharmaceutical Sciences 15 (4), pp. 367-378.
Fulltext not available.
and Schunack, Walter
(2002)
Progress in the proxifan class: heterocyclic congeners as novel potent and selective histamine H3-receptor antagonists.
European Journal of Pharmaceutical Sciences 15 (4), pp. 367-378.
Fulltext not available.
2001
Rostom, Sherif A. F., Farghaly, Ahmed M., Soliman, Farid S. G., El-Semary, Mona M., Elz, Sigurd and Lehmann, Jochen
(2001)
Synthesis and 5-HT2A Antagonist Activity of Derivatives of the Novel Heterocycles Indolo[3,2-d]pyrrolo[3,2-g]azecine and Benzo[d]pyrrolo[3,2-g]azecine compared to the Benz[d]indolo[2,3-g]azecine Derivative LE 300.
Archiv der Pharmazie 334 (7), pp. 241-247.
Fulltext not available.
1994
Monti, J. M., Jantos, H., Leschke, C., Elz, Sigurd and Schunack, W.
(1994)
The selective histamine H1-receptor agonist 2-(3-trifluoromethylphenyl)histamine increases waking in the rat.
European neuropsychopharmacology 4 (4), pp. 459-462.
Fulltext not available.
Lowe, W., Elz, Sigurd, Reiser, H. and Schott, S.
(1994)
[7-fluoro-4-chromone-3-sulfur compounds].
Archiv der Pharmazie 327 (4), pp. 267-269.
Fulltext not available.
1993
Zingel, V., Elz, Sigurd and Schunack, W.
(1993)
Histamine analogues, XXXV: 2-substituted histamine derivatives containing classical moieties of H2-antagonists--a novel class of H1-agonists.
Archiv der Pharmazie 326 (3), pp. 143-151.
Fulltext not available.
Radwansky, A., Elz, Sigurd and Lehmann, J.
(1993)
Lactones, XXY: Synthesis and 5-HT2-receptor affinity of some fluorophenylated alpha-aminomethyllactones.
Archiv der Pharmazie 326 (4), pp. 243-244.
Fulltext not available.
Elz, Sigurd, Zimmermann, H. and Rehse, K.
(1993)
Selectivity of sterically fixed tryptamine and 5-methoxytryptamine derivatives for serotonin receptor subtypes, II: Structure-activity relationships and in vitro pharmacology of N-alkyl- and N,N-dialkyl-3- indolylbicyclo-[2.2.1]-heptane-2-amines.
Archiv der Pharmazie 326 (11), pp. 893-899.
Fulltext not available.
1992
Zingel, V., Elz, Sigurd and Schunack, W.
(1992)
Histamine analogues. 36th communication. Basically substituted histamine derivatives with H1-agonistic activity.
Pharmazie 47 (10), pp. 746-751.
Fulltext not available.
Sellier, Christian, Elz, Sigurd, Buschauer, Armin and Schunack, Walter
(1992)
Histamine analogues: imidazolylalkylguanidines, synthesis and in vitro pharmacology.
European Journal of Medicinal Chemistry 27, pp. 27-32.
Fulltext not available.
Hirschfeld, Jürgen, Buschauer, Armin, Elz, Sigurd, Schunack, Walter, Ruat, Martial, Traiffort, Elisabeth and Schwartz, Jean-Charles
(1992)
Iodoaminopotentidine and related compounds: a new class of ligands with high affinity and selectivity for the histamine H_2-receptor.
Journal of Medicinal Chemistry 35, pp. 2231-2238.
Fulltext not available.
Sellier, Christian, Elz, Sigurd, Buschauer, Armin and Schunack, Walter
(1992)
The effect of lipophilic substituents on the H_2-histaminergic activity of some close analogues of impromidine.
Arch. Pharm. (Weinheim) 325, pp. 471-476.
Fulltext not available.
Sellier, Christian, Elz, Sigurd, Buschauer, Armin and Schunack, Walter
(1992)
Zur Synthese von (Z)- und (E)-3-(1H-imidazol-4-yl)-2-propenamin und einigen 3-(1H-Imidazol-4-yl)propanaminen.
Liebigs Ann. Chem. 1992, pp. 317-322.
Fulltext not available.
1988
Elz, Sigurd, Kimmel, Ursula, Buschauer, Armin and Schunack, Walter
(1988)
Halogenderivate von N-[3-(Imidazol-4-yl)propyl]-N'-(2-phenylthioalkyl)guanidinen.
Sci. Pharm. 56, pp. 229-234.
Fulltext not available.
Elz, Sigurd and Schunack, Walter
(1988)
Impromidin-analoge Guanidine: Synthese und Wirkung am Histamin-H2-Rezeptor. 29. Mitteilung: Histamin-Analoga.
Arzneimittel-Forschung 38 (3), pp. 327-332.
Fulltext not available.
Elz, Sigurd and Schunack, W.
(1988)
[H2-antagonistic activity of the impromidine analog, cyanoguanidine. 37. H2 antihistaminics].
Arzneimittelforschung 38 (1), pp. 7-10.
Fulltext not available.
1987
Elz, Sigurd and Schunack, Walter
(1987)
Darstellung und H2-agonistische Aktivität alkylsubstituierter 3-(Imidazol-4-yl)propylguanidine.
Archiv der Pharmazie 320 (2), pp. 182-185.
Fulltext not available.
1986
Buschauer, Armin, Schickaneder, Helmut, Elz, Sigurd, Schunack, Walter, Szelenyi, Istvan, Baumann, Gert and Ahrens, K.-H.
(1986)
Guanidinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel.
Patentanmeldung P 35 12 084.3 (2.4.1985), Offenlegungsschrift DE 35 12 084 A.
Fulltext not available.
1985
Schunack, Walter, Buschauer, Armin, Büyüktimkim, Servet, Dziuron, Peter, Elz, Sigurd, Gerhardt, Günter, Lebenstedt, Ernst, Lennartz, Hans-Gerd, Schwarz, Siegfried, Spitzhoff, Margrit and Steffens, Robert
(1985)
2. Histamine agonists - chemistry and structure-activity relationships.
In: Dahlbom, R. and Nilsson, J. L. G., (eds.)
VIIIth International Symposium on Medicinal Chemistry.
Swedish Pharmaceutical Press, Stockholm, pp. 169-182.
Fulltext not available.
Buschauer, Armin, Schickaneder, Helmut, Schunack, Walter, Elz, Sigurd, Szelenyi, Istvan, Baumann, Gert and Ahrens, K.-H.
(1985)
Imidazolylalkylguanidine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel.
Patentanmeldung 85 114 205.9 (12.11.1985), Eur. Pat. Appl. EP 0 199 845 (5.11.1986).
Fulltext not available.
1984
Büyüktimkin, Servet, Elz, Sigurd, Dräger, Martin and Schunack, Walter
(1984)
Chinazolinone, 1. Mitt. Darstellung, Kristallstruktur und Wirkung von 2-Methyl-3(4-oxo-3-phenyl-thiazolidin-2-ylidenamino)-4-(3H)-chinazolin on.
Archiv der Pharmazie 317 (9), pp. 797-802.
Fulltext not available.
1983
Elz, Sigurd, Buschauer, Armin, Dräger, M. and Schunack, Walter
(1983)
Darstellung, Eigenschaften und Kristallstruktur der N-[2-(4,5,6,7-Tetrahydro-2-benzimidazolyl)ethyl]phthalamidsäure.
Z. Naturforsch. 38b, pp. 1203-1207.
Fulltext not available.
