Publikationen von Längst, Gernot

Hoffmeister, Helen, Holzinger, Simon, Dürr, Marie-Sofie, Bruckmann, Astrid , Schindler, Susann G., Gröbner-Ferreira, Regina, Depping, Reinhard und Längst, Gernot (2023) Characterization of the nuclear import of the human CHD4–NuRD complex. Journal of Cell Science 136 (7).

Markusch, Hanna, Michl‐Holzinger, Philipp, Obermeyer, Simon, Thorbecke, Claudia, Bruckmann, Astrid , Babl, Sabrina, Längst, Gernot , Osakabe, Akihisa, Berger, Frédéric und Grasser, Klaus D. (2023) Elongation factor 1 is a component of the Arabidopsis RNA polymerase II elongation complex and associates with a subset of transcribed genes. New Phytologist 238 (1), S. 113-124.

Michl-Holzinger, Philipp, Obermeyer, Simon, Markusch, Hanna, Pfab, Alexander, Ettner, Andreas, Bruckmann, Astrid, Babl, Sabrina, Längst, Gernot, Schwartz, Uwe, Tvardovskiy, Andrey, Jensen, Ole N. , Osakabe, Akihisa, Berger, Frédéric und Grasser, Klaus D. (2022) Phosphorylation of the FACT histone chaperone subunit SPT16 affects chromatin at RNA polymerase II transcriptional start sites in Arabidopsis. Nucleic Acids Research 50 (9), S. 5014-5028.

Peterhoff, David , Thalhauser, Stefanie, Neckermann, Patrick , Barbey, Clara, Straub, Kristina, Nazet, Julian, Merkl, Rainer, Längst, Gernot, Breunig, Miriam und Wagner, Ralf (2022) Multivalent display of engineered HIV-1 envelope trimers on silica nanoparticles for targeting and in vitro activation of germline VRC01 B cells. European Journal of Pharmaceutics and Biopharmaceutics 181, S. 88-101. Volltext nicht vorhanden.

Längst, Gernot, Watzlowik, Maria Theresia, Das, Sujaan und Meissner, Markus (2021) Peculiarities of Plasmodium falciparum Gene Regulation and Chromatin Structure. International Journal of Molecular Sciences 2021 (22), S. 5168. (Eingereicht)

Hoffmeister, Helen, Fuchs, Andreas , Komives, Elizabeth, Groebner‐Ferreira, Regina, Strobl, Laura, Nazet, Julian, Heizinger, Leonhard, Merkl, Rainer, Dove, Stefan und Längst, Gernot (2021) Sequence and functional differences in the ATPase domains of CHD3 and SNF2H promise potential for selective regulability and drugability. The FEBS Journal 288, S. 4000-4023.

Kargapolova, Yulia , Rehimi, Rizwan, Kayserili, Hülya , Brühl, Joanna, Sofiadis, Konstantinos, Zirkel, Anne, Palikyras, Spiros, Mizi, Athanasia, Li, Yun, Yigit, Gökhan , Hoischen, Alexander , Frank, Stefan, Russ, Nicole, Trautwein, Jonathan, van Bon, Bregje, Gilissen, Christian , Laugsch, Magdalena, Gusmao, Eduardo Gade, Josipovic, Natasa , Altmüller, Janine, Nürnberg, Peter, Längst, Gernot, Kaiser, Frank J., Watrin, Erwan, Brunner, Han, Rada-Iglesias, Alvaro , Kurian, Leo , Wollnik, Bernd , Bouazoune, Karim und Papantonis, Argyris (2021) Overarching control of autophagy and DNA damage response by CHD6 revealed by modeling a rare human pathology. Nature Communications 12 (1). Volltext nicht vorhanden.

Maiser, Andreas , Dillinger, Stefan, Längst, Gernot, Schermelleh, Lothar , Leonhardt, Heinrich und Németh, Attila (2020) Super-resolution in situ analysis of active ribosomal DNA chromatin organization in the nucleolus. Scientific Reports 10 (7642), S. 1-11.

Minderjahn, Julia, Schmidt, Andreas, Fuchs, Andreas , Schill, Rudolf, Raithel, Johanna, Babina, Magda , Schmidl, C. , Gebhard, Claudia, Schmidhofer, Sandra, Mendes, Karina , Ratermann, Anna, Glatz, Dagmar, Nützel, Margit, Edinger, Matthias, Hoffmann, Petra, Spang, Rainer , Längst, Gernot, Imhof, A. und Rehli, Michael (2020) Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1. Nat Commun 11, S. 402.

Kulich, Ivan, Vogler, Frank, Bleckmann, Andrea, Cyprys, Philipp, Lindemeier, Maria, Fuchs, Ingrid, Krassini, Laura, Schubert, Thomas, Steinbrenner, Jens , Beynon, Jim, Falter-Braun, Pascal, Längst, Gernot, Dresselhaus, Thomas und Sprunck, Stefanie (2020) ARMADILLO REPEAT ONLY proteins confine Rho GTPase signalling to polar growth sites. Nature Plants 6 (10), S. 1275-1288. Volltext nicht vorhanden.

Merkl, Philipp E., Pilsl, Michael, Fremter, Tobias, Schwank, Katrin, Engel, Christoph , Längst, Gernot, Milkereit, Philipp, Griesenbeck, Joachim und Tschochner, Herbert (2020) RNA polymerase I (Pol I) passage through nucleosomes depends on Pol I subunits binding its lobe structure. Journal of Biological Chemistry 295 (15), S. 4782-4795. Volltext nicht vorhanden.

Killian, Tobias, Buntz, Annette, Herlet, Teresa, Seul, Heike, Mundigl, Olaf, Längst, Gernot und Brinkmann, Ulrich (2019) Antibody-targeted chromatin enables effective intracellular delivery and functionality of CRISPR/Cas9 expression plasmids. Nucleic Acids Research 47 (10), e55-e55. Volltext nicht vorhanden.

Hoffmeister, Helen, Fuchs, Andreas , Strobl, Laura, Sprenger, Frank, Gröbner-Ferreira, Regina, Michaelis, Stefanie, Hoffmann, Petra, Nazet, Julian, Merkl, Rainer und Längst, Gernot (2019) Elucidation of the functional roles of the Q and I motifs in the human chromatin-remodeling enzyme BRG1. Journal of Biological Chemistry 294 (9), S. 3294-3310. Volltext nicht vorhanden.

Woloszynska, Magdalena , Le Gall, Sabine, Neyt, Pia , Boccardi, Tommaso M., Grasser, Marion, Längst, Gernot, Aesaert, Stijn, Coussens, Griet, Dhondt, Stijn , Van De Slijke, Eveline, Bruno, Leonardo, Fung-Uceda, Jorge, Mas, Paloma , Van Montagu, Marc, Inzé, Dirk, Himanen, Kristiina , De Jaeger, Geert, Grasser, Klaus D. und Van Lijsebettens, Mieke (2019) Histone 2B monoubiquitination complex integrates transcript elongation with RNA processing at circadian clock and flowering regulators. Proceedings of the National Academy of Sciences 116 (16), S. 8060-8069. Volltext nicht vorhanden.

Maldonado, Rodrigo, Schwartz, Uwe, Silberhorn, Elisabeth und Längst, Gernot (2019) Nucleosomes Stabilize ssRNA-dsDNA Triple Helices in Human Cells. Molecular Cell 73 (6), 1243-1254.e6. Volltext nicht vorhanden.

Ehrnsberger, Hans F., Pfaff, Christina, Hachani, Ines, Flores-Tornero, María , Sørensen, Brian B., Längst, Gernot, Sprunck, Stefanie, Grasser, Marion und Grasser, Klaus D. (2019) The UAP56-Interacting Export Factors UIEF1 and UIEF2 Function in mRNA Export. Plant Physiology 179 (4), S. 1525-1536. Volltext nicht vorhanden.

Azuara-Medina, Paulina Margarita, Sandoval-Duarte, Ariana María, Morales-Lázaro, Sara L., Modragón-González, Ricardo, Vélez-Aguilera, Griselda, Gómez-López, Juan de Dios, Jiménez-Gutiérrez, Guadalupe Elizabeth, Tiburcio-Félix, Reynaldo, Martínez-Vieyra, Ivette, Suárez-Sánchez, Rocío, Längst, Gernot, Magaña, Jonathan Javier, Winder, Steve J., Ortega, Arturo , Ramos Perlingeiro, Rita de Cassia, Jacobs, Laura A. und Cisneros, Bulmaro (2019) The intracellular domain of β-dystroglycan mediates the nucleolar stress response by suppressing UBF transcriptional activity. Cell Death & Disease 10 (3). Volltext nicht vorhanden.

Schwartz, Uwe, Németh, Attila, Diermeier, Sarah , Exler, Josef H., Hansch, Stefan, Maldonado, Rodrigo, Heizinger, Leonhard , Merkl, Rainer und Längst, Gernot (2018) Characterizing the nuclease accessibility of DNA in human cells to map higher order structures of chromatin. Nucleic Acids Research 2018 (1), S. 1-16.

Pfaff, Christina, Ehrnsberger, Hans F., Flores-Tornero, María, Sørensen, Brian B., Schubert, Thomas, Längst, Gernot, Griesenbeck, Joachim, Sprunck, Stefanie, Grasser, Marion und Grasser, Klaus D. (2018) ALY RNA-Binding Proteins Are Required for Nucleocytosolic mRNA Transport and Modulate Plant Growth and Development. Plant Physiology 177 (1), S. 226-240. Volltext nicht vorhanden.

Beck, Alexander, Trippel, Franziska, Wagner, Alexandra, Joppien, Saskia, Felle, Max, Vokuhl, Christian, Schwarzmayr, Thomas, Strom, Tim M., von Schweinitz, Dietrich, Längst, Gernot und Kappler, Roland (2018) Overexpression of UHRF1 promotes silencing of tumor suppressor genes and predicts outcome in hepatoblastoma. Clinical Epigenetics 10 (1). Volltext nicht vorhanden.

Pfab, Alexander , Grønlund, Jesper T., Holzinger, Philipp, Längst, Gernot und Grasser, Klaus D. (2018) The Arabidopsis Histone Chaperone FACT: Role of the HMG-Box Domain of SSRP1. Journal of Molecular Biology 430 (17), S. 2747-2759. Volltext nicht vorhanden.

Kovač, Kristina , Sauer, Anja, Mačinković, Igor, Awe, Stephan, Finkernagel, Florian , Hoffmeister, Helen, Fuchs, Andreas , Müller, Rolf, Rathke, Christina, Längst, Gernot und Brehm, Alexander (2018) Tumour-associated missense mutations in the dMi-2 ATPase alters nucleosome remodelling properties in a mutation-specific manner. Nature Communications 9 (1). Volltext nicht vorhanden.

Hoffmeister, Helen, Fuchs, Andreas , Erdel, Fabian , Pinz, Sophia, Gröbner-Ferreira, Regina, Bruckmann, Astrid, Deutzmann, Rainer, Schwartz, Uwe, Maldonado, Rodrigo, Huber, Claudia, Dendorfer, Anne-Sarah, Rippe, Karsten und Längst, Gernot (2017) CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality. Nucleic Acids Research 45 (18), S. 10534-10554.

Längst, Gernot, König, Fabian und Schubert, Thomas E. O. (2017) The monoclonal S9.6 antibody exhibits highly variable binding affinities towards different R-loop sequences. PLoS ONE 12 (6), e0178875.

Maldonado, Rodrigo, Filarsky, Michael, Grummt, Ingrid und Längst, Gernot (2017) Purine– and pyrimidine–triple-helix-forming oligonucleotides recognize qualitatively different target sites at the ribosomal DNA locus. RNA 24 (3), S. 371-380. Volltext nicht vorhanden.

Sørensen, Brian B., Ehrnsberger, Hans F., Esposito, Silvia, Pfab, Alexander, Bruckmann, Astrid, Hauptmann, Judith, Meister, Gunter, Merkl, Rainer , Schubert, Thomas , Längst, Gernot, Melzer, Michael , Grasser, Marion und Grasser, Klaus D. (2017) The Arabidopsis THO/TREX component TEX1 functionally interacts with MOS11 and modulates mRNA export and alternative splicing events. Plant Molecular Biology 93 (3), S. 283-298. Volltext nicht vorhanden.

Antosz, Wojciech, Pfab, Alexander, Ehrnsberger, Hans F., Holzinger, Philipp, Köllen, Karin, Mortensen, Simon A. , Bruckmann, Astrid, Schubert, Thomas , Längst, Gernot, Griesenbeck, Joachim , Schubert, Veit , Grasser, Marion und Grasser, Klaus D. (2017) The Composition of the Arabidopsis RNA Polymerase II Transcript Elongation Complex Reveals the Interplay between Elongation and mRNA Processing Factors. The Plant Cell 29 (4), S. 854-870. Volltext nicht vorhanden.

Längst, Gernot, Silberhorn, Elisabeth, Schwartz, Uwe, Löffler, Patrick , Schmitz, Samuel, Symelka, Anne , Koning-Ward, Tania de und Merkl, Rainer (2016) Plasmodium falciparum Nucleosomes Exhibit Reduced Stability and Lost Sequence Dependent Nucleosome Positioning. PLoS Pathogens 12 (12), e10060.

Nardocci, Gino, Simonet, Nicolas G. , Navarro, Cristina, Längst, Gernot und Alvarez, Marco (2016) Differential enrichment of TTF-I and Tip5 in the T-like promoter structures of the rDNA contribute to the epigenetic response of Cyprinus carpio during environmental adaptation. Biochemistry and Cell Biology 94 (4), S. 315-321. Volltext nicht vorhanden.

Längst, Gernot, Schrader, Anna, Gross, Thomas und Thalhammer, Verena (2015) Characterization of Dnmt1 Binding and DNA Methylation on Nucleosomes and Nucleosomal Arrays. PLoS ONE 10 (10), e0140076.

Längst, Gernot und Manelyte, Laura (2015) Chromatin remodelers: from function to dysfunction. Genes 2015 (6), S. 299-324.

Friedrich, Ulrike, Datta, Shyamtanu, Schubert, Thomas, Plößl, Karolina, Schneider, Magdalena, Grassmann, Felix, Fuchshofer, Rudolf, Tiefenbach, Klaus-Jürgen, Längst, Gernot und Weber, Bernhard H. F. (2015) Synonymous variants in HTRA1 implicated in AMD susceptibility impair its capacity to regulate TGF-β signaling. Human Molecular Genetics 24, S. 6361-6373. Volltext nicht vorhanden.

Diermeier, Sarah Daniela Helena, Kolovos, Petros, Heizinger, Leonhard, Schwartz, Uwe, Georgomanolis, Theodore, Zirkel, Anne, Wedemann, Gero, Grosveld, Frank, Knoch, Tobias A., Merkl, Rainer, Cook, Peter R., Längst, Gernot und Papatonis, Argyris (2014) TNFα signalling primes chromatin for NF-κB binding and induces rapid and widespread nucleosome repositioning. Genome Biology 15 (12).

Längst, Gernot, Gross, Thomas, Strohner, Ralf und Manelyte, Laura (2014) Chromatin targeting signals nucleosome positioning mechanism and non-coding RNA mediated regulation of the chromatin remodeling complex NoRC. PLoS Genetics 10 (3), e1004157.

Diermeier, Sarah, Nemmeth, Attila, Rehli, Michael, Grummt, Ingrid und Längst, Gernot (2013) Chromatin-Specific Regulation of Mammalian rDNA Transcription by Clustered TTF-I Binding Sites. PLoS Genetics 9.

Kammel, Christine, Thomaier, Maren, Sørensen, Brian B., Schubert, Thomas, Längst, Gernot, Grasser, Marion und Grasser, Klaus D. (2013) Arabidopsis DEAD-box RNA helicase UAP56 interacts with both RNA and DNA as well as with mRNA export factors. PloS one 8 (3), e60644.

Manelyte, Laura und Längst, Gernot (2013) Chromatin Remodelers and Their Way of Action. In: Radzioch, Daniela, (ed.) Chromatin Remodelling. , S. 3. ISBN 978-953-51-1087-3.

Zillner, Karina, Filarsky, Michael, Rachow, Katrin, Weinberger, Michael, Längst, Gernot und Németh, Attila (2013) Large-scale organization of ribosomal DNA chromatin is regulated by Tip5. Nucleic Acids Research 41 (10), S. 5251-5262.

Pham, Thu-Hang, Minderjahn, Julia, Schmidl, Christian, Hoffmeister, Helen, Schmidhofer, Sandra, Chen, Wei, Längst, Gernot, Benner, Christopher und Rehli, Michael (2013) Mechanisms of in vivo binding site selection of the hematopoietic master transcription factor PU.1. Nucleic acids research 41 (13), S. 6391-6402.

Felle, Max, Hoffmeister, Helen, Rothammer, Julia, Fuchs, Andreas, Exler, Josef H. und Längst, Gernot (2011) Nucleosomes protect DNA from DNA methylation in vivo and in vitro. Nucleic Acids Research 39, S. 6956.

Felle, Max, Joppien, Saskia, Németh, Attila, Diermeier, Sarah, Thalhammer, Verena, Dobner, Thomas, Kremmer, Elisabeth, Kappler, Roland und Längst, Gernot (2011) The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1. Nucleic Acids Research 39, S. 8355.

Felle, Max, Exler, Josef H., Merkl, Rainer, Dachauer, Karoline, Brehm, Alexander, Grummt, Ingrid und Längst, Gernot (2010) DNA sequence encoded repression of rRNA gene transcription in chromatin. Nucleic acids research 38 (16), S. 5304-5314. Volltext nicht vorhanden.