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Number of items: 64.

2023

Klemm, Sophie, Evert, Katja , Utpatel, Kirsten , Muggli, Alexandra, Simile, Maria M., Chen, Xin, Evert, Matthias, Calvisi, Diego F. and Scheiter, Alexander (2023) Identification of DUSP4/6 overexpression as a potential rheostat to NRAS-induced hepatocarcinogenesis. BMC Cancer 23.

2022

Scheiter, Alexander , Hierl, Frederik, Lüke, Florian , Keil, Felix , Heudobler, Daniel , Einhell, Sabine, Klier-Richter, Margit, Konstandin, Nikola P., Weber, Florian , Scheiter, Andrea, Kandulski, Arne, Schlosser, Sophie , Cosma, Lidia-Sabina, Tews, Hauke, Weiss, Andreas R. R. , Grube, Matthias, Bumes, Elisabeth , Hau, Peter , Proescholdt, Martin A. , Steger, Felix, Troeger, Anja, Haferkamp, Sebastian , Reibenspies, Lucas E., Schnabel, Marco J., Schulz, Christian , Drexler, Konstantin, Hatzipanagiotou, Maria E., Seitz, Stephan, Klinkhammer-Schalke, Monika, Unberath, Philipp, Calvisi, Diego F. , Pukrop, Tobias , Dietmaier, Wolfgang, Evert, Matthias and Utpatel, Kirsten (2022) Critical evaluation of molecular tumour board outcomes following 2 years of clinical practice in a Comprehensive Cancer Centre. British Journal of Cancer.

Scheiter, Alexander , Hierl, Frederik, Winkel, Ingrid, Keil, Felix, Klier-Richter, Margit, Coulouarn, Cédric, Lüke, Florian, Kandulski, Arne, Evert, Matthias, Dietmaier, Wolfgang, Calvisi, Diego F. and Utpatel, Kirsten (2022) Wnt/β-Catenin-Pathway Alterations and Homologous Recombination Deficiency in Cholangiocarcinoma Cell Lines and Clinical Samples: Towards Specific Vulnerabilities. Journal of Personalized Medicine 12 (8), p. 1270.

Cigliano, Antonio, Zhang, Shanshan, Ribback, Silvia, Steinmann, Sara, Sini, Marcella, Ament, Cindy E., Utpatel, Kirsten, Song, Xinhua, Wang, Jingxiao , Pilo, Maria G., Berger, Fabian, Wang, Haichuan , Tao, Junyan, Li, Xiaolei, Pes, Giovanni M. , Mancarella, Serena, Giannelli, Gianluigi, Dombrowski, Frank, Evert, Matthias, Calvisi, Diego F., Chen, Xin and Evert, Katja (2022) The Hippo pathway effector TAZ induces intrahepatic cholangiocarcinoma in mice and is ubiquitously activated in the human disease. Journal of Experimental & Clinical Cancer Research 41, art.no.192.

Mancarella, Serena, Serino, Grazia, Gigante, Isabella, Cigliano, Antonio, Ribback, Silvia, Sanese, Paola , Grossi, Valentina, Simone, Cristiano, Armentano, Raffaele, Evert, Matthias, Calvisi, Diego F. and Giannelli, Gianluigi (2022) CD90 is regulated by notch1 and hallmarks a more aggressive intrahepatic cholangiocarcinoma phenotype. Journal of Experimental & Clinical Cancer Research 41 (1). Fulltext not available.

Ruiz de Gauna, Mikel, Biancaniello, Francesca, González‐Romero, Francisco , Rodrigues, Pedro M. , Lapitz, Ainhoa, Gómez‐Santos, Beatriz, Olaizola, Paula , Di Matteo, Sabina , Aurrekoetxea, Igor, Labiano, Ibone, Nieva‐Zuluaga, Ane, Benito‐Vicente, Asier, Perugorria, María J., Apodaka‐Biguri, Maider, Paiva, Nuno A., Sáenz de Urturi, Diego, Buqué, Xabier, Delgado, Igotz, Martín, César, Azkargorta, Mikel, Elortza, Felix, Calvisi, Diego F., Andersen, Jesper B., Alvaro, Domenico, Cardinale, Vincenzo, Bujanda, Luis , Banales, Jesús M. and Aspichueta, Patricia (2022) Cholangiocarcinoma progression depends on the uptake and metabolization of extracellular lipids. Hepatology 76 (6), pp. 1617-1633. Fulltext not available.

Mancarella, Serena, Gigante, Isabella, Serino, Grazia, Pizzuto, Elena, Dituri, Francesco, Valentini, Maria F., Wang, Jingxiao, Chen, Xin, Armentano, Raffaele, Calvisi, Diego F. and Giannelli, Gianluigi (2022) Crenigacestat blocking notch pathway reduces liver fibrosis in the surrounding ecosystem of intrahepatic CCA viaTGF-β inhibition. Journal of Experimental & Clinical Cancer Research 41 (1). Fulltext not available.

Zhou, Yi, Tao, Junyan, Calvisi, Diego F. and Chen, Xin (2022) Role of Lipogenesis Rewiring in Hepatocellular Carcinoma. Seminars in Liver Disease 42 (01), 077-086. Fulltext not available.

Wang, Haichuan, Zhang, Shanshan, Zhang, Yi, Jia, Jiaoyuan, Wang, Jingxiao, Liu, Xianqiong, Zhang, Jie, Song, Xinhua, Ribback, Silvia, Cigliano, Antonio, Evert, Matthias, Liang, Bingyong, Wu, Hong, Calvisi, Diego F., Zeng, Yong and Chen, Xin (2022) TAZ is indispensable for c-MYC-induced hepatocarcinogenesis. Journal of Hepatology 76 (1), pp. 123-134. Fulltext not available.

Olaizola, Paula , Lee-Law, Pui Yuen, Fernandez-Barrena, Maite G., Alvarez, Laura, Cadamuro, Massimiliano , Azkargorta, Mikel, O’Rourke, Colm J., Caballero-Camino, Francisco J., Olaizola, Irene , Macias, Rocio I.R. , Marin, Jose J.G. , Serrano-Maciá, Marina , Martinez-Chantar, Maria L., Avila, Matias A. , Aspichueta, Patricia , Calvisi, Diego F., Evert, Matthias, Fabris, Luca, Castro, Rui E. , Elortza, Felix, Andersen, Jesper B., Bujanda, Luis, Rodrigues, Pedro M. , Perugorria, Maria J. and Banales, Jesus M. (2022) Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor-stroma crosstalk in experimental models. Journal of Hepatology 77 (1), pp. 177-190. Fulltext not available.

Zhang, Yi, Xu, Hongwei, Cui, Guofei, Liang, Binyong, Chen, Xiangzheng, Ko, Sungjin, Affo, Silvia, Song, Xinhua, Liao, Yi, Feng, Jianguo, Wang, Pan , Wang, Haichuan , Xu, Meng, Wang, Jingxiao , Pes, Giovanni M. , Ribback, Silvia, Zeng, Yong, Singhi, Aatur, Schwabe, Robert F., Monga, Satdarshan P., Evert, Matthias, Tang, Liling, Calvisi, Diego F. and Chen, Xin (2022) β-Catenin Sustains and Is Required for YES-associated Protein Oncogenic Activity in Cholangiocarcinoma. Gastroenterology 163 (2), pp. 481-494. Fulltext not available.

2021

Scheiter, Alexander, Evert, Katja , Reibenspies, Lucas, Cigliano, Antonio , Annweiler, Katharina, Müller, Karolina , Pöhmerer, Laura-Maria-Giovanna, Xu, Hongwei, Cui, Guofei, Itzel, Timo, Materna-Reichelt, Silvia, Coluccio, Andrea, Honarnejad, Kamran, Teufel, Andreas, Brochhausen, Christoph , Dombrowski, Frank, Chen, Xin, Evert, Matthias, Calvisi, Diego F. and Utpatel, Kirsten (2021) RASSF1A independence and early galectin-1 upregulation in PIK3CA-induced hepatocarcinogenesis: new therapeutic venues. Molecular Oncology 16 (5), pp. 1091-1118.

Evert, Katja , Kocher, Thomas, Schindler, Andrea, Müller, Manuel, Müller, Karolina , Pink, C., Holtfreter, Birte, Schmidt, Alexander, Dombrowski, Frank, Schubert, Andrea, von Woedtke, Thomas, Rupf, Stefan, Calvisi, Diego F., Bekeschus, S. and Jablonowski, L. (2021) Repeated exposure of the oral mucosa over 12 months with cold plasma is not carcinogenic in mice. Scientific Reports 11 (1), p. 20672.

Deng, Shanshan, Solinas, Antonio and Calvisi, Diego F. (2021) Cabozantinib for HCC Treatment, From Clinical Back to Experimental Models. Frontiers in Oncology 2021 (11), pp. 1-12.

Gerthofer, Valeria, Scheiter, Alexander , Lüke, Florian , Keil, Felix , Utpatel, Kirsten , Pöhmerer, Laura-Maria-Giovanna, Seitz, Johannes, Niessen, Christoph, Ignatov, Atanas , Dietmaier, Wolfgang, Calvisi, Diego F., Evert, Matthias, Ortmann, Olaf and Seitz, Stephan (2021) STRN-ALK Fusion in a Case of Malignant Peritoneal Mesothelioma: Mixed Response to Crizotinib, Mode of Resistance, and Brigatinib Sequential Therapy. JCO Precision Oncology 2021 (5), pp. 1507-1513.

Scheiter, Alexander, Keil, Felix, Lüke, Florian, Grosse, Jirka, Verloh, Niklas , Opitz, Sabine, Schlosser, Sophie, Kandulski, Arne, Pukrop, Tobias, Dietmaier, Wolfgang, Evert, Matthias, Calvisi, Diego F. and Utpatel, Kirsten (2021) Identification and In-Depth Analysis of the Novel FGFR2-NDC80 Fusion in a Cholangiocarcinoma Patient: Implication for Therapy. Current Oncology 2021 (28), pp. 1161-1169. (Submitted)

Evert, Katja , Dienemann, Thomas, Brochhausen, Christoph , Lunz, Dirk, Lubnow, Matthias , Ritzka, Markus, Keil, Felix, Trummer, Matthias, Scheiter, Alexander, Salzberger, Bernd , Reischl, Udo, Gessner, Andre , Jantsch, Jonathan, Calvisi, Diego F., Evert, Matthias, Schmidt, Barbara and Simon, Michaela (2021) Autopsy findings after long-term treatment of COVID-19 patients with microbiological correlation. Virchows Archiv 479, pp. 97-108.

Xu, Hongwei, Chen, Kefei, Shang, Runze, Chen, Xinyan, Zhang, Yi, Song, Xinhua, Evert, Matthias, Zhong, Sheng, Li, Bo, Calvisi, Diego F. and Chen, Xin (2021) Alpelisib combination treatment as novel targeted therapy against hepatocellular carcinoma. Cell Death & Disease 12 (10). Fulltext not available.

Cigliano, Antonio, Chen, Xin and Calvisi, Diego F. (2021) Current challenges to underpinning the genetic basis for cholangiocarcinoma. Expert Review of Gastroenterology & Hepatology 15 (5), pp. 511-526. Fulltext not available.

Wang, Haichuan , Wang, Jingxiao , Zhang, Shanshan, Jia, Jiaoyuan, Liu, Xianqiong, Zhang, Jie, Wang, Pan , Song, Xinhua, Che, Li, Liu, Ke, Ribback, Silvia, Cigliano, Antonio , Evert, Matthias, Wu, Hong, Calvisi, Diego F., Zeng, Yong and Chen, Xin (2021) Distinct and Overlapping Roles of Hippo Effectors YAP and TAZ During Human and Mouse Hepatocarcinogenesis. Cellular and Molecular Gastroenterology and Hepatology 11 (4), pp. 1095-1117. Fulltext not available.

Wang, Haichuan , Wang, Pan , Xu, Meng, Song, Xinhua, Wu, Hong, Evert, Matthias, Calvisi, Diego F., Zeng, Yong and Chen, Xin (2021) Distinct functions of transforming growth factor-β signaling in c-MYC driven hepatocellular carcinoma initiation and progression. Cell Death & Disease 12 (2). Fulltext not available.

Vallejo, Adrián, Erice, Oihane, Entrialgo-Cadierno, Rodrigo , Feliu, Iker, Guruceaga, Elizabeth , Perugorria, Maria J., Olaizola, Paula, Muggli, Alexandra, Macaya, Irati, O’Dell, Michael, Ruiz-Fernandez de Cordoba, Borja, Ortiz-Espinosa, Sergio, Hezel, Aram F., Arozarena, Imanol, Lecanda, Fernando, Avila, Matias A. , Fernandez-Barrena, Maite G., Evert, Matthias, Ponz-Sarvise, Mariano , Calvisi, Diego F., Banales, Jesus M. and Vicent, Silve (2021) FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted. Journal of Hepatology 75 (2), pp. 363-376. Fulltext not available.

Pocaterra, Arianna, Scattolin, Gloria , Romani, Patrizia, Ament, Cindy, Ribback, Silvia, Chen, Xin, Evert, Matthias, Calvisi, Diego F. and Dupont, Sirio (2021) Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development. Communications Biology 4 (1). Fulltext not available.

Song, Xinhua, Xu, Hongwei, Wang, Pan , Wang, Jingxiao , Affo, Silvia , Wang, Haichuan , Xu, Meng, Liang, Binyong, Che, Li, Qiu, Wei , Schwabe, Robert F., Chang, Tammy T., Vogl, Marion, Pes, Giovanni M. , Ribback, Silvia, Evert, Matthias, Chen, Xin and Calvisi, Diego F. (2021) Focal adhesion kinase (FAK) promotes cholangiocarcinoma development and progression via YAP activation. Journal of Hepatology 75 (4), pp. 888-899. Fulltext not available.

Wang, Haichuan , Chen, Xin and Calvisi, Diego F. (2021) Hepatocellular carcinoma (HCC): the most promising therapeutic targets in the preclinical arena based on tumor biology characteristics. Expert Opinion on Therapeutic Targets 25 (8), pp. 645-658. Fulltext not available.

Nuernberger, Vincent, Mortoga, Sharif, Metzendorf, Christoph, Burkert, Christian, Ehricke, Katrina, Knuth, Elisa, Zimmer, Jenny, Singer, Stephan, Nath, Neetika, Karim, Majedul, Yasser, Mohd, Calvisi, Diego F., Dombrowski, Frank and Ribback, Silvia (2021) Hormonally Induced Hepatocellular Carcinoma in Diabetic Wild Type and Carbohydrate Responsive Element Binding Protein Knockout Mice. Cells 10 (10), p. 2787. Fulltext not available.

Zhang, Yi, Liang, Binyong, Song, Xinhua, Wang, Haichuan , Evert, Matthias, Zhou, Yi, Calvisi, Diego F., Tang, Liling and Chen, Xin (2021) Loss of Apc Cooperates with Activated Oncogenes to Induce Liver Tumor Formation in Mice. The American Journal of Pathology 191 (5), pp. 930-946. Fulltext not available.

Zhang, Yi, Solinas, Antonio, Cairo, Stefano, Evert, Matthias, Chen, Xin and Calvisi, Diego F. (2021) Molecular Mechanisms of Hepatoblastoma. Seminars in Liver Disease 41 (01), 028-041. Fulltext not available.

Wang, Haichuan , Calvisi, Diego F. and Chen, Xin (2021) Organoids for the Study of Liver Cancer. Seminars in Liver Disease 41 (01), 019-027. Fulltext not available.

Wang, Haichuan , Song, Xinhua, Liao, Haotian, Wang, Pan , Zhang, Yi, Che, Li, Zhang, Jie, Zhou, Yi, Cigliano, Antonio, Ament, Cindy, Superville, Daphne, Ribback, Silvia, Reeves, Melissa, Pes, Giovanni M. , Liang, Binyong, Wu, Hong, Evert, Matthias, Calvisi, Diego F., Zeng, Yong and Chen, Xin (2021) Overexpression of Mothers Against Decapentaplegic Homolog 7 Activates the Yes‐Associated Protein/NOTCH Cascade and Promotes Liver Carcinogenesis in Mice and Humans. Hepatology 74 (1), pp. 248-263. Fulltext not available.

Lu, Xinjun, Paliogiannis, Panagiotis , Calvisi, Diego F. and Chen, Xin (2021) Role of the Mammalian Target of Rapamycin Pathway in Liver Cancer: From Molecular Genetics to Targeted Therapies. Hepatology 73 (S1), pp. 49-61. Fulltext not available.

Pellegrino, Rossella , Thavamani, Abhishek , Calvisi, Diego F., Budczies, Jan, Neumann, Ariane, Geffers, Robert , Kroemer, Jasmin, Greule, Damaris, Schirmacher, Peter, Nordheim, Alfred and Longerich, Thomas (2021) Serum Response Factor (SRF) Drives the Transcriptional Upregulation of the MDM4 Oncogene in HCC. Cancers 13 (2), p. 199. Fulltext not available.

Liang, Binyong, Zhou, Yi, Qian, Manning, Xu, Meng, Wang, Jingxiao , Zhang, Yi, Song, Xinhua, Wang, Haichuan , Lin, Shumei, Ren, Chuanli, Monga, Satdarshan P., Wang, Bruce , Evert, Matthias, Chen, Yifa, Chen, Xiaoping, Huang, Zhiyong, Calvisi, Diego F. and Chen, Xin (2021) TBX3 functions as a tumor suppressor downstream of activated CTNNB1 mutants during hepatocarcinogenesis. Journal of Hepatology 75 (1), pp. 120-131. Fulltext not available.

Lu, Xinjun, Peng, Baogang, Chen, Ge, Pes, Mario G. , Ribback, Silvia, Ament, Cindy , Xu, Hongwei, Pal, Rajesh , Rodrigues, Pedro M. , Banales, Jesus M., Evert, Matthias, Calvisi, Diego F., Chen, Xin, Fan, Biao and Wang, Jingxiao (2021) YAP Accelerates Notch-Driven Cholangiocarcinogenesis via mTORC1 in Mice. The American Journal of Pathology 191 (9), pp. 1651-1667. Fulltext not available.

2020

Döring, Paula, Calvisi, Diego F. and Dombrowski, Frank (2020) Nuclear ErbB2 expression in hepatocytes in liver disease. Virchows Archiv 478 (2), pp. 309-318.

Chen, Xinyan, Kiss, Andras, Schaff, Zsuzsa, Evert, Katja, Zhang, Yi, Zhong, Sheng, Wang, Jingxiao, Evert, Matthias, Calvisi, Diego F. and Chen, Xin (2020) CDK9 is dispensable for YAP‐driven hepatoblastoma development. Pediatric Blood & Cancer 67 (5). Fulltext not available.

Shang, Runze, Song, Xinhua, Wang, Pan, Zhou, Yi, Lu, Xinjun, Wang, Jingxiao, Xu, Meng, Chen, Xinyan, Utpatel, Kirsten, Che, Li, Liang, Binyong, Cigliano, Antonio, Evert, Matthias, Calvisi, Diego F. and Chen, Xin (2020) Cabozantinib-based combination therapy for the treatment of hepatocellular carcinoma. Gut 70 (9), pp. 1746-1757. Fulltext not available.

Banales, Jesus M. , Marin, Jose J. G., Lamarca, Angela, Rodrigues, Pedro M. , Khan, Shahid A., Roberts, Lewis R. , Cardinale, Vincenzo, Carpino, Guido, Andersen, Jesper B., Braconi, Chiara, Calvisi, Diego F., Perugorria, Maria J., Fabris, Luca, Boulter, Luke, Macias, Rocio I. R., Gaudio, Eugenio, Alvaro, Domenico, Gradilone, Sergio A., Strazzabosco, Mario, Marzioni, Marco, Coulouarn, Cédric, Fouassier, Laura , Raggi, Chiara, Invernizzi, Pietro, Mertens, Joachim C., Moncsek, Anja, Rizvi, Sumera, Heimbach, Julie, Koerkamp, Bas Groot, Bruix, Jordi , Forner, Alejandro, Bridgewater, John, Valle, Juan W. and Gores, Gregory J. (2020) Cholangiocarcinoma 2020: the next horizon in mechanisms and management. Nature Reviews Gastroenterology & Hepatology 17 (9), pp. 557-588. Fulltext not available.

Mancarella, Serena, Serino, Grazia, Dituri, Francesco, Cigliano, Antonio , Ribback, Silvia, Wang, Jingxiao, Chen, Xin, Calvisi, Diego F. and Giannelli, Gianluigi (2020) Crenigacestat, a selective NOTCH1 inhibitor, reduces intrahepatic cholangiocarcinoma progression by blocking VEGFA/DLL4/MMP13 axis. Cell Death & Differentiation 27 (8), pp. 2330-2343. Fulltext not available.

Chen, Bin , Garmire, Lana, Calvisi, Diego F., Chua, Mei-Sze, Kelley, Robin K. and Chen, Xin (2020) Harnessing big ‘omics’ data and AI for drug discovery in hepatocellular carcinoma. Nature Reviews Gastroenterology & Hepatology 17 (4), pp. 238-251. Fulltext not available.

Cigliano, Antonio , Pilo, M. G., Mela, M., Evert, Matthias, Calvisi, Diego F., Utpatel, Kirsten , make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference and make_name_string expected hash reference (2020) Inhibition of MELK Protooncogene as an Innovative Treatment for Intrahepatic Cholangiocarcinoma. Medicina 56, p. 1.

Zhou, Yi, Xu, Meng, Liu, Pin, Liang, Binyong, Qian, Manning, Wang, Haichuan , Song, Xinhua, Nyshadham, Pranavanand, Che, Li, Calvisi, Diego F., Li, Feng, Lin, Shumei and Chen, Xin (2020) Mammalian Target of Rapamycin Complex 2 Signaling Is Required for Liver Regeneration in a Cholestatic Liver Injury Murine Model. The American Journal of Pathology 190 (7), pp. 1414-1426. Fulltext not available.

Wang, Pan , Song, Xinhua, Cao, Dan, Cui, Kairong, Wang, Jingxiao , Utpatel, Kirsten, Shang, Runze , Wang, Haichuan , Che, Li, Evert, Matthias, Zhao, Keji, Calvisi, Diego F. and Chen, Xin (2020) Oncogene-dependent function of BRG1 in hepatocarcinogenesis. Cell Death & Disease 11 (2). Fulltext not available.

Jia, Jiaoyuan, Che, Li, Cigliano, Antonio , Wang, Xue, Peitta, Graziella, Tao, Junyan, Zhong, Sheng, Ribback, Silvia, Evert, Matthias, Chen, Xin and Calvisi, Diego F. (2020) Pivotal Role of Fatty Acid Synthase in c-MYC Driven Hepatocarcinogenesis. International Journal of Molecular Sciences 21 (22), p. 8467. Fulltext not available.

Zhang, Shu, Zhang, Jie, Evert, Katja, Li, Xiaolei, Liu, Pin, Kiss, Andras, Schaff, Zsuzsa, Ament, Cindy , Zhang, Yi, Serra, Monica, Evert, Matthias, Chen, Nianyong, Xu, Feng, Chen, Xin, Tao, Junyan, Calvisi, Diego F. and Cigliano, Antonio (2020) The Hippo Effector Transcriptional Coactivator with PDZ-Binding Motif Cooperates with Oncogenic β-Catenin to Induce Hepatoblastoma Development in Mice and Humans. The American Journal of Pathology 190 (7), pp. 1397-1413. Fulltext not available.

Metzendorf, Christoph , Wineberger, Katharina, Rausch, Jenny, Cigliano, Antonio , Peters, Kristin, Sun, Baodong, Mennerich, Daniela, Kietzmann, Thomas, Calvisi, Diego F., Dombrowski, Frank and Ribback, Silvia (2020) Transcriptomic and Proteomic Analysis of Clear Cell Foci (CCF) in the Human Non-Cirrhotic Liver Identifies Several Differentially Expressed Genes and Proteins with Functions in Cancer Cell Biology and Glycogen Metabolism. Molecules 25 (18), p. 4141. Fulltext not available.

Xu, Meng, Wang, Haichuan , Wang, Jingxiao , Burhan, Deviana , Shang, Runze , Wang, Pan , Zhou, Yi, Li, Rong, Liang, Bingyong, Evert, Katja, Utpatel, Kirsten, Xu, Zhong, Song, Xinhua, Che, Li, Calvisi, Diego F., Wang, Bruce , Chen, Xi, Zeng, Yong and Chen, Xin (2020) mTORC2 Signaling Is Necessary for Timely Liver Regeneration after Partial Hepatectomy. The American Journal of Pathology 190 (4), pp. 817-829. Fulltext not available.

2019

Che, Li, Paliogiannis, Panagiotis, Cigliano, Antonio , Pilo, Maria G., Chen, Xin and Calvisi, Diego F. (2019) Pathogenetic, Prognostic, and Therapeutic Role of Fatty Acid Synthase in Human Hepatocellular Carcinoma. Frontiers in Oncology 9 (1412), pp. 1-10.

Qiao, Yu, Wang, Jingxiao, Karagoz, Eylul, Liang, Binyong, Song, Xinhua, Shang, Runze, Evert, Katja, Xu, Meng, Che, Li, Evert, Matthias, Calvisi, Diego F., Tao, Junyan, Wang, Bruce, Monga, Satdarshan P. and Chen, Xin (2019) Axis inhibition protein 1 (Axin1) Deletion–Induced Hepatocarcinogenesis Requires Intact β‐Catenin but Not Notch Cascade in Mice. Hepatology 70 (6), pp. 2003-2017. Fulltext not available.

Che, Li, Chi, Wenna, Qiao, Yu, Zhang, Jie, Song, Xinhua, Liu, Ye, Li, Lei, Jia, Jiaoyuan, Pilo, Maria G., Wang, Jingxiao, Cigliano, Antonio , Ma, Zhilong, Kuang, Wenhua, Tang, Zefang, Zhang, Zemin, Shui, Guanghou, Ribback, Silvia, Dombrowski, Frank, Evert, Matthias, Pascale, Rosa Maria, Cossu, Carla, Pes, Giovanni Mario , Osborne, Timothy F., Calvisi, Diego F., Chen, Xin and Chen, Ligong (2019) Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans. Gut 69 (1), pp. 177-186. Fulltext not available.

Liu, Xianqiong, Hu, Junjie, Song, Xinhua, Utpatel, Kirsten, Evert, Matthias and Calvisi, Diego F. (2019) Combined treatment with MEK and mTOR inhibitors is effective in vitro and in vivo models of hepatocellular carcinoma. Cancers 11, p. 930.

Erice, O., Vallejo, A., Ponz-Sarvise, M., Saborowski, M. and Calvisi, Diego F. (2019) Genetic Mouse Models as In Vivo Tools for Cholangiocarcinoma Research. Cancers 11, p. 1868.

Drucker, Elisabeth, Holzer, Kerstin, Pusch, Stefan, Winkler, Juliane, Calvisi, Diego F., Eiteneuer, Eva, Herpel, Esther, Goeppert, Benjamin, Roessler, Stephanie , Ori, Alessandro, Schirmacher, Peter, Breuhahn, Kai and Singer, Stephan (2019) Karyopherin α2-dependent import of E2F1 and TFDP1 maintains protumorigenic stathmin expression in liver cancer. Cell Communication and Signaling 17 (1). Fulltext not available.

Wang, Jingxiao , Wang, Haichuan , Peters, Michele, Ding, Ning, Ribback, Silvia, Utpatel, Kirsten, Cigliano, Antonio, Dombrowski, Frank, Xu, Meng, Chen, Xinyan, Song, Xinhua, Che, Li, Evert, Matthias, Cossu, Antonio, Gordan, John, Zeng, Yong, Chen, Xin and Calvisi, Diego F. (2019) Loss of Fbxw7 synergizes with activated Akt signaling to promote c-Myc dependent cholangiocarcinogenesis. Journal of Hepatology 71 (4), pp. 742-752. Fulltext not available.

Wang, Pan, Song, Xinhua, Utpatel, Kirsten, Shang, Runze, Yang, Yoon Mee, Xu, Meng, Zhang, Jie, Che, Li, Gordan, John, Cigliano, Antonio, Seki, Ekihiro , Evert, Matthias, Calvisi, Diego F., Hu, Xiaosong and Chen, Xin (2019) MEK inhibition suppresses K-Ras wild-type cholangiocarcinoma in vitro and in vivo via inhibiting cell proliferation and modulating tumor microenvironment. Cell Death & Disease 10 (2). Fulltext not available.

Xu, Meng, Wang, Jingxiao, Xu, Zhong, Li, Rong, Wang, Pan, Shang, Runze, Cigliano, Antonio, Ribback, Silvia, Solinas, Antonio , Pes, Giovanni Mario , Evert, Katja, Wang, Haichuan, Song, Xinhua, Zhang, Shu, Che, Li, Pascale, Rosa Maria, Calvisi, Diego F., Liu, Qingguang and Chen, Xin (2019) SNAI1 promotes the cholangiocellular phenotype, but not epithelial-mesenchymal transition, in a murine hepatocellular carcinoma model. Cancer Research 79 (21), pp. 5563-5574. Fulltext not available.

Xu, Zhong, Xu, Meng, Liu, Pin, Zhang, Shu, Shang, Runze, Qiao, Yu, Che, Li, Ribback, Silvia, Cigliano, Antonio, Evert, Katja, Pascale, Rosa M., Dombrowski, Frank, Evert, Matthias, Chen, Xi, Calvisi, Diego F. and Chen, Xin (2019) The mTORC2‐Akt1 Cascade Is Crucial for c‐Myc to Promote Hepatocarcinogenesis in Mice and Humans. Hepatology 70 (5), pp. 1600-1613. Fulltext not available.

2018

Song, Xinhua, Liu, Xianqiong, Wang, Haichuan , Wang, Jingxiao , Qiao, Yu, Cigliano, Antonio, Utpatel, Kirsten, Ribback, Silvia, Pilo, Maria G., Serra, Marina, Gordan, John D., Che, Li, Zhang, Shanshan, Cossu, Antonio, Porcu, Alberto, Pascale, Rosa M., Dombrowski, Frank, Hu, Hongbo, Calvisi, Diego F., Evert, Matthias and Chen, Xin (2018) Combined CDK4/6 and Pan-mTOR Inhibition Is Synergistic Against Intrahepatic Cholangiocarcinoma. Clinical Cancer Research 25 (1), pp. 403-413. Fulltext not available.

Dong, Mingjie, Liu, Xianqiong, Evert, Katja, Utpatel, Kirsten, Peters, Michele, Zhang, Shanshan, Xu, Zhong, Che, Li, Cigliano, Antonio , Ribback, Silvia, Dombrowski, Frank, Cossu, Antonio, Gordan, John, Calvisi, Diego F., Evert, Matthias, Liu, Yan and Chen, Xin (2018) Efficacy of MEK inhibition in a K-Ras-driven cholangiocarcinoma preclinical model. Cell Death & Disease 9 (2). Fulltext not available.

2017

Cigliano, Antonio , Wang, Chunmei, Pilo, Maria G., Szydlowska, Marta , Brozzetti, Stefania , Latte, Gavinella, Pes, Giovanni M., Pascale, Rosa M., Seddaiu, Maria A., Vidili, Gianpaolo, Ribback, Silvia, Dombrowski, Frank, Evert, Matthias, Chen, Xin and Calvisi, Diego F. (2017) Inhibition of HSF1 suppresses the growth of hepatocarcinoma cell lines <i>in vitro</i> and AKT-driven hepatocarcinogenesis in mice. Oncotarget 8 (33). Fulltext not available.

Che, Li, Pilo, Maria G., Cigliano, Antonio , Latte, Gavinella , Simile, Maria M., Ribback, Silvia, Dombrowski, Frank, Evert, Matthias, Chen, Xin and Calvisi, Diego F. (2017) Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma. Cell Cycle 16 (6), pp. 499-507. Fulltext not available.

Zhang, Shanshan, Song, Xinhua, Cao, Dan, Xu, Zhong, Fan, Biao, Che, Li, Hu, Junjie, Chen, Bin, Dong, Mingjie, Pilo, Maria G., Cigliano, Antonio , Evert, Katja, Ribback, Silvia, Dombrowski, Frank, Pascale, Rosa M., Cossu, Antonio, Vidili, Gianpaolo, Porcu, Alberto, Simile, Maria M., Pes, Giovanni M., Giannelli, Gianluigi, Gordan, John, Wei, Lixin, Evert, Matthias, Cong, Wenming, Calvisi, Diego F. and Chen, Xin (2017) Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice. Journal of Hepatology 67 (6), pp. 1194-1203. Fulltext not available.

2016

Wang, Chunmei, Che, Li, Hu, Junjie, Zhang, Shanshan, Jiang, Lijie, Latte, Gavinella , Demartis, Maria I., Tao, Junyan, Gui, Bing, Pilo, Maria G., Ribback, Silvia, Dombrowski, Frank, Evert, Matthias, Calvisi, Diego F. and Chen, Xin (2016) Activated mutant forms of PIK3CA cooperate with RasV12 or c-Met to induce liver tumour formation in mice via AKT2/mTORC1 cascade. Liver International 36 (8), pp. 1176-1186. Fulltext not available.

Hu, Junjie, Che, Li, Li, Lei, Pilo, Maria G., Cigliano, Antonio , Ribback, Silvia, Li, Xiaolei, Latte, Gavinella , Mela, Marta, Evert, Matthias, Dombrowski, Frank, Zheng, Guohua, Chen, Xin and Calvisi, Diego F. (2016) Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice. Scientific Reports 6 (1). Fulltext not available.

This list was generated on Mon Dec 2 23:36:38 2024 CET.
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