Number of items: 64.
2023
Klemm, Sophie,
Evert, Katja ,
Utpatel, Kirsten ,
Muggli, Alexandra,
Simile, Maria M.,
Chen, Xin,
Evert, Matthias,
Calvisi, Diego F. and
Scheiter, Alexander
(2023)
Identification of DUSP4/6 overexpression as a potential rheostat to NRAS-induced hepatocarcinogenesis.
BMC Cancer 23.
2022
Scheiter, Alexander ,
Hierl, Frederik,
Lüke, Florian ,
Keil, Felix ,
Heudobler, Daniel ,
Einhell, Sabine,
Klier-Richter, Margit,
Konstandin, Nikola P.,
Weber, Florian ,
Scheiter, Andrea,
Kandulski, Arne,
Schlosser, Sophie ,
Cosma, Lidia-Sabina,
Tews, Hauke,
Weiss, Andreas R. R. ,
Grube, Matthias,
Bumes, Elisabeth ,
Hau, Peter ,
Proescholdt, Martin A. ,
Steger, Felix,
Troeger, Anja,
Haferkamp, Sebastian ,
Reibenspies, Lucas E.,
Schnabel, Marco J.,
Schulz, Christian ,
Drexler, Konstantin,
Hatzipanagiotou, Maria E.,
Seitz, Stephan,
Klinkhammer-Schalke, Monika,
Unberath, Philipp,
Calvisi, Diego F. ,
Pukrop, Tobias ,
Dietmaier, Wolfgang,
Evert, Matthias and
Utpatel, Kirsten
(2022)
Critical evaluation of molecular tumour board outcomes following 2 years of clinical practice in a Comprehensive Cancer Centre.
British Journal of Cancer.
Scheiter, Alexander ,
Hierl, Frederik,
Winkel, Ingrid,
Keil, Felix,
Klier-Richter, Margit,
Coulouarn, Cédric,
Lüke, Florian,
Kandulski, Arne,
Evert, Matthias,
Dietmaier, Wolfgang,
Calvisi, Diego F. and
Utpatel, Kirsten
(2022)
Wnt/β-Catenin-Pathway Alterations and Homologous Recombination Deficiency in Cholangiocarcinoma Cell Lines and Clinical Samples: Towards Specific Vulnerabilities.
Journal of Personalized Medicine 12 (8), p. 1270.
Cigliano, Antonio,
Zhang, Shanshan,
Ribback, Silvia,
Steinmann, Sara,
Sini, Marcella,
Ament, Cindy E.,
Utpatel, Kirsten,
Song, Xinhua,
Wang, Jingxiao ,
Pilo, Maria G.,
Berger, Fabian,
Wang, Haichuan ,
Tao, Junyan,
Li, Xiaolei,
Pes, Giovanni M. ,
Mancarella, Serena,
Giannelli, Gianluigi,
Dombrowski, Frank,
Evert, Matthias,
Calvisi, Diego F.,
Chen, Xin and
Evert, Katja
(2022)
The Hippo pathway effector TAZ induces intrahepatic cholangiocarcinoma in mice and is ubiquitously activated in the human disease.
Journal of Experimental & Clinical Cancer Research 41, art.no.192.
Mancarella, Serena,
Serino, Grazia,
Gigante, Isabella,
Cigliano, Antonio,
Ribback, Silvia,
Sanese, Paola ,
Grossi, Valentina,
Simone, Cristiano,
Armentano, Raffaele,
Evert, Matthias,
Calvisi, Diego F. and
Giannelli, Gianluigi
(2022)
CD90 is regulated by notch1 and hallmarks a more aggressive intrahepatic cholangiocarcinoma phenotype.
Journal of Experimental & Clinical Cancer Research 41 (1).
Fulltext not available.
Ruiz de Gauna, Mikel,
Biancaniello, Francesca,
González‐Romero, Francisco ,
Rodrigues, Pedro M. ,
Lapitz, Ainhoa,
Gómez‐Santos, Beatriz,
Olaizola, Paula ,
Di Matteo, Sabina ,
Aurrekoetxea, Igor,
Labiano, Ibone,
Nieva‐Zuluaga, Ane,
Benito‐Vicente, Asier,
Perugorria, María J.,
Apodaka‐Biguri, Maider,
Paiva, Nuno A.,
Sáenz de Urturi, Diego,
Buqué, Xabier,
Delgado, Igotz,
Martín, César,
Azkargorta, Mikel,
Elortza, Felix,
Calvisi, Diego F.,
Andersen, Jesper B.,
Alvaro, Domenico,
Cardinale, Vincenzo,
Bujanda, Luis ,
Banales, Jesús M. and
Aspichueta, Patricia
(2022)
Cholangiocarcinoma progression depends on the uptake and metabolization of extracellular lipids.
Hepatology 76 (6), pp. 1617-1633.
Fulltext not available.
Mancarella, Serena,
Gigante, Isabella,
Serino, Grazia,
Pizzuto, Elena,
Dituri, Francesco,
Valentini, Maria F.,
Wang, Jingxiao,
Chen, Xin,
Armentano, Raffaele,
Calvisi, Diego F. and
Giannelli, Gianluigi
(2022)
Crenigacestat blocking notch pathway reduces liver fibrosis in the surrounding ecosystem of intrahepatic CCA viaTGF-β inhibition.
Journal of Experimental & Clinical Cancer Research 41 (1).
Fulltext not available.
Wang, Haichuan,
Zhang, Shanshan,
Zhang, Yi,
Jia, Jiaoyuan,
Wang, Jingxiao,
Liu, Xianqiong,
Zhang, Jie,
Song, Xinhua,
Ribback, Silvia,
Cigliano, Antonio,
Evert, Matthias,
Liang, Bingyong,
Wu, Hong,
Calvisi, Diego F.,
Zeng, Yong and
Chen, Xin
(2022)
TAZ is indispensable for c-MYC-induced hepatocarcinogenesis.
Journal of Hepatology 76 (1), pp. 123-134.
Fulltext not available.
Olaizola, Paula ,
Lee-Law, Pui Yuen,
Fernandez-Barrena, Maite G.,
Alvarez, Laura,
Cadamuro, Massimiliano ,
Azkargorta, Mikel,
O’Rourke, Colm J.,
Caballero-Camino, Francisco J.,
Olaizola, Irene ,
Macias, Rocio I.R. ,
Marin, Jose J.G. ,
Serrano-Maciá, Marina ,
Martinez-Chantar, Maria L.,
Avila, Matias A. ,
Aspichueta, Patricia ,
Calvisi, Diego F.,
Evert, Matthias,
Fabris, Luca,
Castro, Rui E. ,
Elortza, Felix,
Andersen, Jesper B.,
Bujanda, Luis,
Rodrigues, Pedro M. ,
Perugorria, Maria J. and
Banales, Jesus M.
(2022)
Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor-stroma crosstalk in experimental models.
Journal of Hepatology 77 (1), pp. 177-190.
Fulltext not available.
Zhang, Yi,
Xu, Hongwei,
Cui, Guofei,
Liang, Binyong,
Chen, Xiangzheng,
Ko, Sungjin,
Affo, Silvia,
Song, Xinhua,
Liao, Yi,
Feng, Jianguo,
Wang, Pan ,
Wang, Haichuan ,
Xu, Meng,
Wang, Jingxiao ,
Pes, Giovanni M. ,
Ribback, Silvia,
Zeng, Yong,
Singhi, Aatur,
Schwabe, Robert F.,
Monga, Satdarshan P.,
Evert, Matthias,
Tang, Liling,
Calvisi, Diego F. and
Chen, Xin
(2022)
β-Catenin Sustains and Is Required for YES-associated Protein Oncogenic Activity in Cholangiocarcinoma.
Gastroenterology 163 (2), pp. 481-494.
Fulltext not available.
2021
Scheiter, Alexander,
Evert, Katja ,
Reibenspies, Lucas,
Cigliano, Antonio ,
Annweiler, Katharina,
Müller, Karolina ,
Pöhmerer, Laura-Maria-Giovanna,
Xu, Hongwei,
Cui, Guofei,
Itzel, Timo,
Materna-Reichelt, Silvia,
Coluccio, Andrea,
Honarnejad, Kamran,
Teufel, Andreas,
Brochhausen, Christoph ,
Dombrowski, Frank,
Chen, Xin,
Evert, Matthias,
Calvisi, Diego F. and
Utpatel, Kirsten
(2021)
RASSF1A independence and early galectin-1 upregulation in PIK3CA-induced hepatocarcinogenesis: new therapeutic venues.
Molecular Oncology 16 (5), pp. 1091-1118.
Evert, Katja ,
Kocher, Thomas,
Schindler, Andrea,
Müller, Manuel,
Müller, Karolina ,
Pink, C.,
Holtfreter, Birte,
Schmidt, Alexander,
Dombrowski, Frank,
Schubert, Andrea,
von Woedtke, Thomas,
Rupf, Stefan,
Calvisi, Diego F.,
Bekeschus, S. and
Jablonowski, L.
(2021)
Repeated exposure of the oral mucosa over 12 months with cold plasma is not carcinogenic in mice.
Scientific Reports 11 (1), p. 20672.
Gerthofer, Valeria,
Scheiter, Alexander ,
Lüke, Florian ,
Keil, Felix ,
Utpatel, Kirsten ,
Pöhmerer, Laura-Maria-Giovanna,
Seitz, Johannes,
Niessen, Christoph,
Ignatov, Atanas ,
Dietmaier, Wolfgang,
Calvisi, Diego F.,
Evert, Matthias,
Ortmann, Olaf and
Seitz, Stephan
(2021)
STRN-ALK Fusion in a Case of Malignant Peritoneal Mesothelioma: Mixed Response to Crizotinib, Mode of Resistance, and Brigatinib Sequential Therapy.
JCO Precision Oncology 2021 (5), pp. 1507-1513.
Scheiter, Alexander,
Keil, Felix,
Lüke, Florian,
Grosse, Jirka,
Verloh, Niklas ,
Opitz, Sabine,
Schlosser, Sophie,
Kandulski, Arne,
Pukrop, Tobias,
Dietmaier, Wolfgang,
Evert, Matthias,
Calvisi, Diego F. and
Utpatel, Kirsten
(2021)
Identification and In-Depth Analysis of the Novel FGFR2-NDC80 Fusion in a Cholangiocarcinoma Patient: Implication for Therapy.
Current Oncology 2021 (28), pp. 1161-1169.
(Submitted)
Evert, Katja ,
Dienemann, Thomas,
Brochhausen, Christoph ,
Lunz, Dirk,
Lubnow, Matthias ,
Ritzka, Markus,
Keil, Felix,
Trummer, Matthias,
Scheiter, Alexander,
Salzberger, Bernd ,
Reischl, Udo,
Gessner, Andre ,
Jantsch, Jonathan,
Calvisi, Diego F.,
Evert, Matthias,
Schmidt, Barbara and
Simon, Michaela
(2021)
Autopsy findings after long-term treatment of COVID-19 patients with microbiological correlation.
Virchows Archiv 479, pp. 97-108.
Xu, Hongwei,
Chen, Kefei,
Shang, Runze,
Chen, Xinyan,
Zhang, Yi,
Song, Xinhua,
Evert, Matthias,
Zhong, Sheng,
Li, Bo,
Calvisi, Diego F. and
Chen, Xin
(2021)
Alpelisib combination treatment as novel targeted therapy against hepatocellular carcinoma.
Cell Death & Disease 12 (10).
Fulltext not available.
Wang, Haichuan ,
Wang, Jingxiao ,
Zhang, Shanshan,
Jia, Jiaoyuan,
Liu, Xianqiong,
Zhang, Jie,
Wang, Pan ,
Song, Xinhua,
Che, Li,
Liu, Ke,
Ribback, Silvia,
Cigliano, Antonio ,
Evert, Matthias,
Wu, Hong,
Calvisi, Diego F.,
Zeng, Yong and
Chen, Xin
(2021)
Distinct and Overlapping Roles of Hippo Effectors YAP and TAZ During Human and Mouse Hepatocarcinogenesis.
Cellular and Molecular Gastroenterology and Hepatology 11 (4), pp. 1095-1117.
Fulltext not available.
Wang, Haichuan ,
Wang, Pan ,
Xu, Meng,
Song, Xinhua,
Wu, Hong,
Evert, Matthias,
Calvisi, Diego F.,
Zeng, Yong and
Chen, Xin
(2021)
Distinct functions of transforming growth factor-β signaling in c-MYC driven hepatocellular carcinoma initiation and progression.
Cell Death & Disease 12 (2).
Fulltext not available.
Vallejo, Adrián,
Erice, Oihane,
Entrialgo-Cadierno, Rodrigo ,
Feliu, Iker,
Guruceaga, Elizabeth ,
Perugorria, Maria J.,
Olaizola, Paula,
Muggli, Alexandra,
Macaya, Irati,
O’Dell, Michael,
Ruiz-Fernandez de Cordoba, Borja,
Ortiz-Espinosa, Sergio,
Hezel, Aram F.,
Arozarena, Imanol,
Lecanda, Fernando,
Avila, Matias A. ,
Fernandez-Barrena, Maite G.,
Evert, Matthias,
Ponz-Sarvise, Mariano ,
Calvisi, Diego F.,
Banales, Jesus M. and
Vicent, Silve
(2021)
FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted.
Journal of Hepatology 75 (2), pp. 363-376.
Fulltext not available.
Pocaterra, Arianna,
Scattolin, Gloria ,
Romani, Patrizia,
Ament, Cindy,
Ribback, Silvia,
Chen, Xin,
Evert, Matthias,
Calvisi, Diego F. and
Dupont, Sirio
(2021)
Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development.
Communications Biology 4 (1).
Fulltext not available.
Song, Xinhua,
Xu, Hongwei,
Wang, Pan ,
Wang, Jingxiao ,
Affo, Silvia ,
Wang, Haichuan ,
Xu, Meng,
Liang, Binyong,
Che, Li,
Qiu, Wei ,
Schwabe, Robert F.,
Chang, Tammy T.,
Vogl, Marion,
Pes, Giovanni M. ,
Ribback, Silvia,
Evert, Matthias,
Chen, Xin and
Calvisi, Diego F.
(2021)
Focal adhesion kinase (FAK) promotes cholangiocarcinoma development and progression via YAP activation.
Journal of Hepatology 75 (4), pp. 888-899.
Fulltext not available.
Nuernberger, Vincent,
Mortoga, Sharif,
Metzendorf, Christoph,
Burkert, Christian,
Ehricke, Katrina,
Knuth, Elisa,
Zimmer, Jenny,
Singer, Stephan,
Nath, Neetika,
Karim, Majedul,
Yasser, Mohd,
Calvisi, Diego F.,
Dombrowski, Frank and
Ribback, Silvia
(2021)
Hormonally Induced Hepatocellular Carcinoma in Diabetic Wild Type and Carbohydrate Responsive Element Binding Protein Knockout Mice.
Cells 10 (10), p. 2787.
Fulltext not available.
Zhang, Yi,
Liang, Binyong,
Song, Xinhua,
Wang, Haichuan ,
Evert, Matthias,
Zhou, Yi,
Calvisi, Diego F.,
Tang, Liling and
Chen, Xin
(2021)
Loss of Apc Cooperates with Activated Oncogenes to Induce Liver Tumor Formation in Mice.
The American Journal of Pathology 191 (5), pp. 930-946.
Fulltext not available.
Zhang, Yi,
Solinas, Antonio,
Cairo, Stefano,
Evert, Matthias,
Chen, Xin and
Calvisi, Diego F.
(2021)
Molecular Mechanisms of Hepatoblastoma.
Seminars in Liver Disease 41 (01), 028-041.
Fulltext not available.
Wang, Haichuan ,
Song, Xinhua,
Liao, Haotian,
Wang, Pan ,
Zhang, Yi,
Che, Li,
Zhang, Jie,
Zhou, Yi,
Cigliano, Antonio,
Ament, Cindy,
Superville, Daphne,
Ribback, Silvia,
Reeves, Melissa,
Pes, Giovanni M. ,
Liang, Binyong,
Wu, Hong,
Evert, Matthias,
Calvisi, Diego F.,
Zeng, Yong and
Chen, Xin
(2021)
Overexpression of Mothers Against Decapentaplegic Homolog 7 Activates the Yes‐Associated Protein/NOTCH Cascade and Promotes Liver Carcinogenesis in Mice and Humans.
Hepatology 74 (1), pp. 248-263.
Fulltext not available.
Pellegrino, Rossella ,
Thavamani, Abhishek ,
Calvisi, Diego F.,
Budczies, Jan,
Neumann, Ariane,
Geffers, Robert ,
Kroemer, Jasmin,
Greule, Damaris,
Schirmacher, Peter,
Nordheim, Alfred and
Longerich, Thomas
(2021)
Serum Response Factor (SRF) Drives the Transcriptional Upregulation of the MDM4 Oncogene in HCC.
Cancers 13 (2), p. 199.
Fulltext not available.
Liang, Binyong,
Zhou, Yi,
Qian, Manning,
Xu, Meng,
Wang, Jingxiao ,
Zhang, Yi,
Song, Xinhua,
Wang, Haichuan ,
Lin, Shumei,
Ren, Chuanli,
Monga, Satdarshan P.,
Wang, Bruce ,
Evert, Matthias,
Chen, Yifa,
Chen, Xiaoping,
Huang, Zhiyong,
Calvisi, Diego F. and
Chen, Xin
(2021)
TBX3 functions as a tumor suppressor downstream of activated CTNNB1 mutants during hepatocarcinogenesis.
Journal of Hepatology 75 (1), pp. 120-131.
Fulltext not available.
Lu, Xinjun,
Peng, Baogang,
Chen, Ge,
Pes, Mario G. ,
Ribback, Silvia,
Ament, Cindy ,
Xu, Hongwei,
Pal, Rajesh ,
Rodrigues, Pedro M. ,
Banales, Jesus M.,
Evert, Matthias,
Calvisi, Diego F.,
Chen, Xin,
Fan, Biao and
Wang, Jingxiao
(2021)
YAP Accelerates Notch-Driven Cholangiocarcinogenesis via mTORC1 in Mice.
The American Journal of Pathology 191 (9), pp. 1651-1667.
Fulltext not available.
2020
Chen, Xinyan,
Kiss, Andras,
Schaff, Zsuzsa,
Evert, Katja,
Zhang, Yi,
Zhong, Sheng,
Wang, Jingxiao,
Evert, Matthias,
Calvisi, Diego F. and
Chen, Xin
(2020)
CDK9 is dispensable for YAP‐driven hepatoblastoma development.
Pediatric Blood & Cancer 67 (5).
Fulltext not available.
Shang, Runze,
Song, Xinhua,
Wang, Pan,
Zhou, Yi,
Lu, Xinjun,
Wang, Jingxiao,
Xu, Meng,
Chen, Xinyan,
Utpatel, Kirsten,
Che, Li,
Liang, Binyong,
Cigliano, Antonio,
Evert, Matthias,
Calvisi, Diego F. and
Chen, Xin
(2020)
Cabozantinib-based combination therapy for the treatment of hepatocellular carcinoma.
Gut 70 (9), pp. 1746-1757.
Fulltext not available.
Banales, Jesus M. ,
Marin, Jose J. G.,
Lamarca, Angela,
Rodrigues, Pedro M. ,
Khan, Shahid A.,
Roberts, Lewis R. ,
Cardinale, Vincenzo,
Carpino, Guido,
Andersen, Jesper B.,
Braconi, Chiara,
Calvisi, Diego F.,
Perugorria, Maria J.,
Fabris, Luca,
Boulter, Luke,
Macias, Rocio I. R.,
Gaudio, Eugenio,
Alvaro, Domenico,
Gradilone, Sergio A.,
Strazzabosco, Mario,
Marzioni, Marco,
Coulouarn, Cédric,
Fouassier, Laura ,
Raggi, Chiara,
Invernizzi, Pietro,
Mertens, Joachim C.,
Moncsek, Anja,
Rizvi, Sumera,
Heimbach, Julie,
Koerkamp, Bas Groot,
Bruix, Jordi ,
Forner, Alejandro,
Bridgewater, John,
Valle, Juan W. and
Gores, Gregory J.
(2020)
Cholangiocarcinoma 2020: the next horizon in mechanisms and management.
Nature Reviews Gastroenterology & Hepatology 17 (9), pp. 557-588.
Fulltext not available.
Mancarella, Serena,
Serino, Grazia,
Dituri, Francesco,
Cigliano, Antonio ,
Ribback, Silvia,
Wang, Jingxiao,
Chen, Xin,
Calvisi, Diego F. and
Giannelli, Gianluigi
(2020)
Crenigacestat, a selective NOTCH1 inhibitor, reduces intrahepatic cholangiocarcinoma progression by blocking VEGFA/DLL4/MMP13 axis.
Cell Death & Differentiation 27 (8), pp. 2330-2343.
Fulltext not available.
Chen, Bin ,
Garmire, Lana,
Calvisi, Diego F.,
Chua, Mei-Sze,
Kelley, Robin K. and
Chen, Xin
(2020)
Harnessing big ‘omics’ data and AI for drug discovery in hepatocellular carcinoma.
Nature Reviews Gastroenterology & Hepatology 17 (4), pp. 238-251.
Fulltext not available.
Cigliano, Antonio ,
Pilo, M. G.,
Mela, M.,
Evert, Matthias,
Calvisi, Diego F.,
Utpatel, Kirsten ,
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(2020)
Inhibition of MELK Protooncogene as an Innovative Treatment for Intrahepatic Cholangiocarcinoma.
Medicina 56, p. 1.
Zhou, Yi,
Xu, Meng,
Liu, Pin,
Liang, Binyong,
Qian, Manning,
Wang, Haichuan ,
Song, Xinhua,
Nyshadham, Pranavanand,
Che, Li,
Calvisi, Diego F.,
Li, Feng,
Lin, Shumei and
Chen, Xin
(2020)
Mammalian Target of Rapamycin Complex 2 Signaling Is Required for Liver Regeneration in a Cholestatic Liver Injury Murine Model.
The American Journal of Pathology 190 (7), pp. 1414-1426.
Fulltext not available.
Wang, Pan ,
Song, Xinhua,
Cao, Dan,
Cui, Kairong,
Wang, Jingxiao ,
Utpatel, Kirsten,
Shang, Runze ,
Wang, Haichuan ,
Che, Li,
Evert, Matthias,
Zhao, Keji,
Calvisi, Diego F. and
Chen, Xin
(2020)
Oncogene-dependent function of BRG1 in hepatocarcinogenesis.
Cell Death & Disease 11 (2).
Fulltext not available.
Jia, Jiaoyuan,
Che, Li,
Cigliano, Antonio ,
Wang, Xue,
Peitta, Graziella,
Tao, Junyan,
Zhong, Sheng,
Ribback, Silvia,
Evert, Matthias,
Chen, Xin and
Calvisi, Diego F.
(2020)
Pivotal Role of Fatty Acid Synthase in c-MYC Driven Hepatocarcinogenesis.
International Journal of Molecular Sciences 21 (22), p. 8467.
Fulltext not available.
Zhang, Shu,
Zhang, Jie,
Evert, Katja,
Li, Xiaolei,
Liu, Pin,
Kiss, Andras,
Schaff, Zsuzsa,
Ament, Cindy ,
Zhang, Yi,
Serra, Monica,
Evert, Matthias,
Chen, Nianyong,
Xu, Feng,
Chen, Xin,
Tao, Junyan,
Calvisi, Diego F. and
Cigliano, Antonio
(2020)
The Hippo Effector Transcriptional Coactivator with PDZ-Binding Motif Cooperates with Oncogenic β-Catenin to Induce Hepatoblastoma Development in Mice and Humans.
The American Journal of Pathology 190 (7), pp. 1397-1413.
Fulltext not available.
Metzendorf, Christoph ,
Wineberger, Katharina,
Rausch, Jenny,
Cigliano, Antonio ,
Peters, Kristin,
Sun, Baodong,
Mennerich, Daniela,
Kietzmann, Thomas,
Calvisi, Diego F.,
Dombrowski, Frank and
Ribback, Silvia
(2020)
Transcriptomic and Proteomic Analysis of Clear Cell Foci (CCF) in the Human Non-Cirrhotic Liver Identifies Several Differentially Expressed Genes and Proteins with Functions in Cancer Cell Biology and Glycogen Metabolism.
Molecules 25 (18), p. 4141.
Fulltext not available.
Xu, Meng,
Wang, Haichuan ,
Wang, Jingxiao ,
Burhan, Deviana ,
Shang, Runze ,
Wang, Pan ,
Zhou, Yi,
Li, Rong,
Liang, Bingyong,
Evert, Katja,
Utpatel, Kirsten,
Xu, Zhong,
Song, Xinhua,
Che, Li,
Calvisi, Diego F.,
Wang, Bruce ,
Chen, Xi,
Zeng, Yong and
Chen, Xin
(2020)
mTORC2 Signaling Is Necessary for Timely Liver Regeneration after Partial Hepatectomy.
The American Journal of Pathology 190 (4), pp. 817-829.
Fulltext not available.
2019
Che, Li,
Paliogiannis, Panagiotis,
Cigliano, Antonio ,
Pilo, Maria G.,
Chen, Xin and
Calvisi, Diego F.
(2019)
Pathogenetic, Prognostic, and Therapeutic Role of Fatty Acid Synthase in Human Hepatocellular Carcinoma.
Frontiers in Oncology 9 (1412), pp. 1-10.
Qiao, Yu,
Wang, Jingxiao,
Karagoz, Eylul,
Liang, Binyong,
Song, Xinhua,
Shang, Runze,
Evert, Katja,
Xu, Meng,
Che, Li,
Evert, Matthias,
Calvisi, Diego F.,
Tao, Junyan,
Wang, Bruce,
Monga, Satdarshan P. and
Chen, Xin
(2019)
Axis inhibition protein 1 (Axin1) Deletion–Induced Hepatocarcinogenesis Requires Intact β‐Catenin but Not Notch Cascade in Mice.
Hepatology 70 (6), pp. 2003-2017.
Fulltext not available.
Che, Li,
Chi, Wenna,
Qiao, Yu,
Zhang, Jie,
Song, Xinhua,
Liu, Ye,
Li, Lei,
Jia, Jiaoyuan,
Pilo, Maria G.,
Wang, Jingxiao,
Cigliano, Antonio ,
Ma, Zhilong,
Kuang, Wenhua,
Tang, Zefang,
Zhang, Zemin,
Shui, Guanghou,
Ribback, Silvia,
Dombrowski, Frank,
Evert, Matthias,
Pascale, Rosa Maria,
Cossu, Carla,
Pes, Giovanni Mario ,
Osborne, Timothy F.,
Calvisi, Diego F.,
Chen, Xin and
Chen, Ligong
(2019)
Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans.
Gut 69 (1), pp. 177-186.
Fulltext not available.
Liu, Xianqiong,
Hu, Junjie,
Song, Xinhua,
Utpatel, Kirsten,
Evert, Matthias and
Calvisi, Diego F.
(2019)
Combined treatment with MEK and mTOR inhibitors is effective in vitro and in vivo models of hepatocellular carcinoma.
Cancers 11, p. 930.
Drucker, Elisabeth,
Holzer, Kerstin,
Pusch, Stefan,
Winkler, Juliane,
Calvisi, Diego F.,
Eiteneuer, Eva,
Herpel, Esther,
Goeppert, Benjamin,
Roessler, Stephanie ,
Ori, Alessandro,
Schirmacher, Peter,
Breuhahn, Kai and
Singer, Stephan
(2019)
Karyopherin α2-dependent import of E2F1 and TFDP1 maintains protumorigenic stathmin expression in liver cancer.
Cell Communication and Signaling 17 (1).
Fulltext not available.
Wang, Jingxiao ,
Wang, Haichuan ,
Peters, Michele,
Ding, Ning,
Ribback, Silvia,
Utpatel, Kirsten,
Cigliano, Antonio,
Dombrowski, Frank,
Xu, Meng,
Chen, Xinyan,
Song, Xinhua,
Che, Li,
Evert, Matthias,
Cossu, Antonio,
Gordan, John,
Zeng, Yong,
Chen, Xin and
Calvisi, Diego F.
(2019)
Loss of Fbxw7 synergizes with activated Akt signaling to promote c-Myc dependent cholangiocarcinogenesis.
Journal of Hepatology 71 (4), pp. 742-752.
Fulltext not available.
Wang, Pan,
Song, Xinhua,
Utpatel, Kirsten,
Shang, Runze,
Yang, Yoon Mee,
Xu, Meng,
Zhang, Jie,
Che, Li,
Gordan, John,
Cigliano, Antonio,
Seki, Ekihiro ,
Evert, Matthias,
Calvisi, Diego F.,
Hu, Xiaosong and
Chen, Xin
(2019)
MEK inhibition suppresses K-Ras wild-type cholangiocarcinoma in vitro and in vivo via inhibiting cell proliferation and modulating tumor microenvironment.
Cell Death & Disease 10 (2).
Fulltext not available.
Xu, Meng,
Wang, Jingxiao,
Xu, Zhong,
Li, Rong,
Wang, Pan,
Shang, Runze,
Cigliano, Antonio,
Ribback, Silvia,
Solinas, Antonio ,
Pes, Giovanni Mario ,
Evert, Katja,
Wang, Haichuan,
Song, Xinhua,
Zhang, Shu,
Che, Li,
Pascale, Rosa Maria,
Calvisi, Diego F.,
Liu, Qingguang and
Chen, Xin
(2019)
SNAI1 promotes the cholangiocellular phenotype, but not epithelial-mesenchymal transition, in a murine hepatocellular carcinoma model.
Cancer Research 79 (21), pp. 5563-5574.
Fulltext not available.
Xu, Zhong,
Xu, Meng,
Liu, Pin,
Zhang, Shu,
Shang, Runze,
Qiao, Yu,
Che, Li,
Ribback, Silvia,
Cigliano, Antonio,
Evert, Katja,
Pascale, Rosa M.,
Dombrowski, Frank,
Evert, Matthias,
Chen, Xi,
Calvisi, Diego F. and
Chen, Xin
(2019)
The mTORC2‐Akt1 Cascade Is Crucial for c‐Myc to Promote Hepatocarcinogenesis in Mice and Humans.
Hepatology 70 (5), pp. 1600-1613.
Fulltext not available.
2018
Song, Xinhua,
Liu, Xianqiong,
Wang, Haichuan ,
Wang, Jingxiao ,
Qiao, Yu,
Cigliano, Antonio,
Utpatel, Kirsten,
Ribback, Silvia,
Pilo, Maria G.,
Serra, Marina,
Gordan, John D.,
Che, Li,
Zhang, Shanshan,
Cossu, Antonio,
Porcu, Alberto,
Pascale, Rosa M.,
Dombrowski, Frank,
Hu, Hongbo,
Calvisi, Diego F.,
Evert, Matthias and
Chen, Xin
(2018)
Combined CDK4/6 and Pan-mTOR Inhibition Is Synergistic Against Intrahepatic Cholangiocarcinoma.
Clinical Cancer Research 25 (1), pp. 403-413.
Fulltext not available.
Dong, Mingjie,
Liu, Xianqiong,
Evert, Katja,
Utpatel, Kirsten,
Peters, Michele,
Zhang, Shanshan,
Xu, Zhong,
Che, Li,
Cigliano, Antonio ,
Ribback, Silvia,
Dombrowski, Frank,
Cossu, Antonio,
Gordan, John,
Calvisi, Diego F.,
Evert, Matthias,
Liu, Yan and
Chen, Xin
(2018)
Efficacy of MEK inhibition in a K-Ras-driven cholangiocarcinoma preclinical model.
Cell Death & Disease 9 (2).
Fulltext not available.
2017
Cigliano, Antonio ,
Wang, Chunmei,
Pilo, Maria G.,
Szydlowska, Marta ,
Brozzetti, Stefania ,
Latte, Gavinella,
Pes, Giovanni M.,
Pascale, Rosa M.,
Seddaiu, Maria A.,
Vidili, Gianpaolo,
Ribback, Silvia,
Dombrowski, Frank,
Evert, Matthias,
Chen, Xin and
Calvisi, Diego F.
(2017)
Inhibition of HSF1 suppresses the growth of hepatocarcinoma cell lines <i>in vitro</i> and AKT-driven hepatocarcinogenesis in mice.
Oncotarget 8 (33).
Fulltext not available.
Che, Li,
Pilo, Maria G.,
Cigliano, Antonio ,
Latte, Gavinella ,
Simile, Maria M.,
Ribback, Silvia,
Dombrowski, Frank,
Evert, Matthias,
Chen, Xin and
Calvisi, Diego F.
(2017)
Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma.
Cell Cycle 16 (6), pp. 499-507.
Fulltext not available.
Zhang, Shanshan,
Song, Xinhua,
Cao, Dan,
Xu, Zhong,
Fan, Biao,
Che, Li,
Hu, Junjie,
Chen, Bin,
Dong, Mingjie,
Pilo, Maria G.,
Cigliano, Antonio ,
Evert, Katja,
Ribback, Silvia,
Dombrowski, Frank,
Pascale, Rosa M.,
Cossu, Antonio,
Vidili, Gianpaolo,
Porcu, Alberto,
Simile, Maria M.,
Pes, Giovanni M.,
Giannelli, Gianluigi,
Gordan, John,
Wei, Lixin,
Evert, Matthias,
Cong, Wenming,
Calvisi, Diego F. and
Chen, Xin
(2017)
Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice.
Journal of Hepatology 67 (6), pp. 1194-1203.
Fulltext not available.
2016
Wang, Chunmei,
Che, Li,
Hu, Junjie,
Zhang, Shanshan,
Jiang, Lijie,
Latte, Gavinella ,
Demartis, Maria I.,
Tao, Junyan,
Gui, Bing,
Pilo, Maria G.,
Ribback, Silvia,
Dombrowski, Frank,
Evert, Matthias,
Calvisi, Diego F. and
Chen, Xin
(2016)
Activated mutant forms of PIK3CA cooperate with RasV12 or c-Met to induce liver tumour formation in mice via AKT2/mTORC1 cascade.
Liver International 36 (8), pp. 1176-1186.
Fulltext not available.
Hu, Junjie,
Che, Li,
Li, Lei,
Pilo, Maria G.,
Cigliano, Antonio ,
Ribback, Silvia,
Li, Xiaolei,
Latte, Gavinella ,
Mela, Marta,
Evert, Matthias,
Dombrowski, Frank,
Zheng, Guohua,
Chen, Xin and
Calvisi, Diego F.
(2016)
Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice.
Scientific Reports 6 (1).
Fulltext not available.
This list was generated on Mon Dec 2 23:36:38 2024 CET.