Anzahl der Einträge: 50.
2010
Ott, I.,
Kowalski, K.,
Gust, Ronald,
Maurer, Jörg,
Mücke, P. und
Winter, Rainer F.
(2010)
Comparative biological evaluation of two ethylene linked mixed binuclear ferrocene/ruthenium organometallic species.
Bioorg. Chem. Med. Lett 20, S. 866-869.
Volltext nicht vorhanden.
2009
2007
Schertl, Sabine,
Hartmann, Rolf W.,
Batzl-Hartmann, Christine,
Spruss, Thilo,
Maucher, Anton,
Angerer, Erwin von,
Schiller, Claus D.,
Schneider, Martin R.,
Gust, Ronald und
Schönenberger, Helmut
(2007)
Platinum(II) complexes interfering with testicular steroid biosynthesis: drugs for the therapy of advanced or recurrent prostate cancers? Preclinical studies.
Journal of Cancer Research and Clinical Oncology 133 (3), S. 153-167.
Volltext nicht vorhanden.
2005
2004
Schertl, Sabine,
Hartmann, Rolf W.,
Batzl-Hartmann, Christine,
Bernhardt, Günther,
Spruß, Thilo,
Beckenlehner, Karin,
Koch, Marion,
Krauser, Rudolf,
Schlemmer, Richard,
Gust, Ronald und
Schönenberger, Helmut
(2004)
[1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action I: antitumor activity due to the reduction of the endogenous estrogen level.
Archiv der Pharmazie 337 (6), S. 335-348.
Volltext nicht vorhanden.
Schertl, Sabine,
Hartmann, Rolf W.,
Batzl-Hartmann, Christine,
Bernhardt, Günther,
Spruss, Thilo,
Beckenlehner, Karin,
Koch, Marion,
Krauser, Rudolf,
Schlemmer, Richard,
Gust, Ronald und
Schönenberger, Helmut
(2004)
[1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action II: contribution of drug inactivation, cellular drug uptake and sterical factors in the drug-target interaction to the antitumor activity.
Archiv der Pharmazie 337 (6), S. 349-359.
Volltext nicht vorhanden.
2001
Schertl, Sabine,
Hartmann, Rolf W.,
Batzl-Hartmann, Christine,
Schlemmer, Richard,
Spruß, Thilo,
Bernhardt, Günther,
Gust, Ronald und
Schönenberger, Helmut
(2001)
1-(2,6-dichloro-4-hydroxyphenyl)-2-phenylethanes--new biological response modifiers for the therapy of breast cancer. Synthesis and evaluation of estrogenic/antiestrogenic properties.
Archiv der Pharmazie 334 (4), S. 125-137.
Volltext nicht vorhanden.
2000
1999
Bernhardt, Günther,
Koch, Marion,
Spruss, Thilo,
Gust, Ronald,
Krauser, Rudolf,
Schlemmer, Richard,
Hollstein, Michael,
Lux, Franz und
Schönenberger, Helmut
(1999)
[meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] sulfatoplatinum(II)--pharmacokinetic studies.
Archiv der Pharmazie 332 (6), S. 195-200.
Volltext nicht vorhanden.
1998
Gust, Ronald,
Schnurr, Beate,
Krauser, Rudolf,
Bernhardt, Günther,
Koch, Marion,
Schmid, Beate,
Hummel, Evelyn und
Schönenberger, Helmut
(1998)
Stability and cellular studies of [rac-1,2-bis(4-fluorophenyl)ethylenediamine][cyclobutane-1,1-dicarboxylato]platinum(II), a novel, highly active carboplatin derivative.
Journal of Cancer Research and Clinical Oncology 124 (11), S. 585-597.
Volltext nicht vorhanden.
1997
Gust, Ronald,
Gelbcke, Michael,
Angermaier, Bernhard,
Bachmann, Helmut,
Krauser, Rudolf und
Schönenberger, Helmut
(1997)
The stereoselectivity of antitumor active [1,2-diamino-1-phenylpropane]dichloroplatinum(II) complexes.
Inorganica chimica acta 264 (1-2), S. 145-160.
Volltext nicht vorhanden.
1996
1995
Gust, Ronald,
Bernhardt, Günther,
Spruss, Thilo,
Krauser, Rudolf,
Koch, Marion,
Schönenberger, Helmut,
Bauer, Kurt H.,
Schertl, Sabine und
Lu, Zhi
(1995)
Development of a parenterally administrable hydrosol preparation of the "third generation platinum complex" [(+/-)-1,2-bis(4-fluorophenyl)ethylenediamine]dichloroplatinum(II). Part 1. Preparation and studies on the stability and antitumor activity.
Archiv der Pharmazie 328 (9), S. 645-653.
Volltext nicht vorhanden.
Gust, Ronald,
Bernhardt, Günther,
Spruss, Thilo,
Krauser, Rudolf,
Koch, Marion,
Schönenberger, Helmut,
Bauer, Kurt-Heinz,
Schertl, Sabine und
Lu, Zhi
(1995)
Development of a parenterally administrable hydrosol preparation of the third generation platinum complex [(+-)-1,2-bis(4-fluorophenyl)ethylenediamine]dichloroplatinum(II). Part 1. Preparation and studies on the stability and antitumor activity.
Archiv der Pharmazie (Weinheim, Germany) 328 (9), S. 645-653.
Volltext nicht vorhanden.
Gust, Ronald,
Niebler, Karlheinz und
Schönenberger, Helmut
(1995)
Investigation of the Configurational and Conformational Influences on the Hormonal Activity of 1,2-Bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamines and of their Platinum(II) Complexes. 1. Synthesis, Estradiol Receptor Affinity, and Estrogenic Activity of Diastereomeric [N-Alkyl- and N,N'-Dialkyl-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]dichloroplatinum(II) Complexes.
Journal of Medicinal Chemistry 38 (12), S. 2070-2079.
Volltext nicht vorhanden.
1994
Nikolov, G. S.,
Trendavilova, N.,
Schönenberger, Helmut,
Gust, Ronald,
Kritzenberger, J. und
Yersin, Hartmut
(1994)
Molecular mechanical and quantum chemical study on the species involved in the hydrolysis of cis-diaminedichloro-platinum(II) and substituted bis(ethylenediamine)dichloro-platinum(II) complexes. Part I. Reactans and products.
Inorganica Chimica Acta 217 (1-2), S. 159-170.
Volltext nicht vorhanden.
Nikolov, G. S.,
Trendafilova, N.,
Schönenberger, Helmut,
Gust, Ronald,
Kritzenberger, J. und
Yersin, Hartmut
(1994)
Molecular mechanical and quantum chemical study on the species involved in the hydrolysis of cis-diamminedichloroplatinum(II) and substituted bis(ethylenediamine)dichloroplatinum(II) complexes. Part I. Reactants and products.
Inorganica chimica acta 217 (1-2), S. 159-170.
Volltext nicht vorhanden.
1993
Gust, Ronald,
Schönenberger, Helmut,
Range, Klaus Juergen,
Klement, Ulrich und
Schneider, Martin
(1993)
Crystal structure and hormonal activity of 1,1-bis(4-hydroxyphenyl)-2-phenylethene.
Monatshefte für Chemie 124 (11-12), S. 1181-1193.
Volltext nicht vorhanden.
Gust, Ronald,
Schönenberger, Helmut,
Kritzenberger, Juergen,
Range, Klaus Juergen,
Klement, Ulrich und
Burgemeister, Thomas
(1993)
Crystal structure, solution chemistry, and antitumor activity of diastereomeric [1,2-bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II) complexes.
Inorganic chemistry 32 (26), S. 5939-5950.
Volltext nicht vorhanden.
Kritzenberger, J.,
Bernhardt, Günther,
Gust, Ronald,
Pistor, Petra,
Schönenberger, Helmut und
Yersin, Hartmut
(1993)
Dichlorobis(cycloalkylamine)platinum(II) complexes. Structure activity relationship on the human MDA-MB-231 breast cancer cell line.
Monatshefte fuer Chemie 124 (5), S. 587-604.
Spruss, Thilo,
Schertl, Sabine,
Schneider, Martin R.,
Gust, Ronald,
Bauer, Kurt und
Schönenberger, Helmut
(1993)
[Meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] -dichloroplatinum(II), a new drug not only parenterally but also orally active in the therapy of breast and prostate cancer.
Journal of cancer research and clinical oncology 119 (12), S. 707-716.
Volltext nicht vorhanden.
1992
Bernhardt, Günther,
Müller, Richard,
Gust, Ronald,
Reile, Herta,
Keller, Christoph,
Spruss, Thilo und
Schönenberger, Helmut
(1992)
Dichloro-[1-(hydroxyphenyl)-2-phenylethylenediamine]platinum(II) complexes: testing on the human ovarian cancer cell lines NIH: OVCAR3 and SK OV 3.
Archiv der Pharmazie 325 (2), S. 93-99.
Schertl, Sabine,
Gust, Ronald,
Müller, Richard,
Spruss, Thilo und
Schönenberger, Helmut
(1992)
Stereoisomeric [1,2-bis(3-hydroxyphenyl)ethylenediamine]platinum(II) complexes. Part III. Evaluation of the mammary tumor inhibiting properties.
Archiv der Pharmazie 325 (2), S. 113-118.
Volltext nicht vorhanden.
Bernhardt, Günther,
Gust, Ronald,
Reile, Herta,
vom Orde, Hans Dieter,
Müller, Richard,
Keller, Christoph,
Spruß, Thilo,
Schönenberger, Helmut,
Burgemeister, Thomas,
Mannschreck, Albrecht,
Range, Klaus-Jürgen und
Klement, Ulrich
(1992)
[1,2-Bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer. II. Synthesis and preliminary testing of the enantiomeric complexes.
Journal of cancer research and clinical oncology 118 (3), S. 201-208.
Bernhardt, Günther,
Gust, Ronald,
Reile, Herta,
vom Orde, Hans Dieter,
Müller, Richard,
Keller, Christoph,
Spruß, Thilo,
Schönenberger, Helmut,
Burgemeister, Thomas,
Mannschreck, Albrecht,
Range, Klaus Jürgen und
Klement, Ulrich
(1992)
[1,2-Bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer. III. Detailed evaluation of the antitumor activity of the enantiomeric complexes on the human NIH:OVCAR-3 ovarian cancer cell line.
Journal of cancer research and clinical oncology 118 (3), S. 209-215.
1991
Bernhardt, Günther,
Reile, Herta,
Spruss, Thilo,
Koch, Marion,
Gust, Ronald,
Schönenberger, Helmut,
Hollstein, Michael,
Lux, Franz und
Engel, Jürgen
(1991)
D-17446.
Drugs of the Future 16 (10), S. 899-903.
Reile, Herta,
Spruß, Thilo,
Bernhardt, Günther,
Müller, Richard,
Gust, Ronald und
Schönenberger, Helmut
(1991)
Tumor inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes. Part IV: Biological evaluation--in vivo studies on the P 388 leukemia.
Archiv der Pharmazie 324 (7), S. 405-409.
1990
Spruss, Thilo,
Gust, Ronald,
Müller, Richard,
Engel, Juergen und
Schönenberger, Helmut
(1990)
Mammary-tumor-inhibiting properties of (S,S)-[1,2-bis(4-hydroxyphenyl)ethylenediamine]dichloroplatinum(II).
Archiv der Pharmazie 323 (2), S. 99-102.
Volltext nicht vorhanden.
Reile, Herta,
Spruß, Thilo,
Müller, Richard,
Gust, Ronald,
Bernhardt, Günther,
Schönenberger, Helmut und
Engel, Jürgen
(1990)
Tumor inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes, III: Evaluation of the mammary tumor inhibiting properties.
Archiv der Pharmazie 323 (5), S. 301-306.
Reile, Herta,
Müller, Richard,
Gust, Ronald,
Laske, Reiner,
Krischke, Walter,
Bernhardt, Günther,
Spruss, Thilo,
Jennerwein, Margaretha,
Engel, Jürgen und
Seeber, Siegfried
(1990)
Tumor inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes. Part II: Biological evaluation-in vitro studies on the P 388 D1 leukemia cell line.
Archiv der Pharmazie 323 (3), S. 133-140.
vom Orde, Hans Dieter,
Reile, Herta,
Müller, Richard,
Gust, Ronald,
Bernhardt, Günther,
Spruß, Thilo,
Schönenberger, Helmut,
Burgemeister, Thomas und
Mannschreck, Albrecht
(1990)
Tumor-inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes. V. Synthesis and evaluation of enantiomeric [1,2-bis-(4-fluorophenyl)ethylenediamine]dichloroplatinum(II) complexes.
Journal of cancer research and clinical oncology 116 (5), S. 434-438.
Müller, Richard,
Gust, Ronald,
Bernhardt, Günther,
Keller, Christoph,
Schönenberger, Helmut,
Seeber, Siegfried,
Osieka, Reinhardt,
Eastman, Alan und
Jennerwein, Margaretha
(1990)
[DL-1,2-bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer.
Journal of cancer research and clinical oncology 116 (3), S. 237-244.
1989
Mueller, Richard,
Gust, Ronald,
Jennerwein, Margaretha,
Reile, Herta,
Laske, Reiner,
Krischke, Walter,
Bernhardt, Günther,
Spruss, Thilo,
Engel, Juergen und
Schönenberger, Helmut
(1989)
Tumor inhibiting [1,2-bis(fluorophenylethylenediamine]platinum(II) complexes. Part I. Synthesis.
European Journal of Medicinal Chemistry 24 (4), S. 341-348.
Jennerwein, Margaretha,
Gust, Ronald,
Müller, Richard,
Schönenberger, Helmut,
Engel, Juergen,
Berger, Martin R.,
Schmaehl, Dietrich,
Seeber, Siegfried und
Osieka, Reinhardt
(1989)
Tumor inhibiting properties of stereoisomeric [1,2-bis(3-hydroxyphenyl)ethylenediamine]dichloroplatinum(II) complexes. Part I. Synthesis.
Archiv der Pharmazie 322 (1), S. 25-29.
Volltext nicht vorhanden.
Jennerwein, Margaretha,
Gust, Ronald,
Müller, Richard,
Schönenberger, Helmut,
Engel, Juergen,
Berger, Martin R.,
Schmaehl, Dietrich,
Seeber, Siegfried und
Osieka, Reinhardt
(1989)
Tumor inhibiting properties of stereoisomeric [1,2-bis(3-hydroxyphenyl)ethylenediamine]dichloroplatinum(II)-complexes. Part II. Biological properties.
Archiv der Pharmazie 322 (2), S. 67-73.
Volltext nicht vorhanden.
1988
Jennerwein, M.,
Wappes, B.,
Gust, Ronald,
Schönenberger, Helmut,
Engel, J.,
Seeber, S. und
Osieka, R.
(1988)
Influence of ring substituents on the antitumor effect of dichloro(1,2-diphenylethylenediamine)platinum(II) complexes.
Journal of cancer research and clinical oncology 114 (4), S. 347-358.
Volltext nicht vorhanden.
Karl, Johann,
Gust, Ronald,
Spruss, Thilo,
Schneider, Martin R.,
Schönenberger, Helmut,
Engel, Juergen,
Wrobel, Karl Heinz,
Lux, Franz und
Trebert-Haeberlin, Susanne
(1988)
Ring-substituted [1,2-bis(4-hydroxyphenyl)ethylenediamine]dichloroplatinum(II) complexes: compounds with a selective effect on the hormone-dependent mammary carcinoma.
Journal of medicinal chemistry 31 (1), S. 72-83.
Volltext nicht vorhanden.
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