Publikationen von Grässel, Susanne

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Anzahl der Einträge: 49.

Wang, Chenglong, Stöckl, Sabine, Pattappa, Girish

, Schulz, Daniela

, Hofmann, Korbinian, Ilic, Jovana, Reinders, Yvonne, Bauer, Richard J.

, Sickmann, Albert

und Grässel, Susanne

(2023) Extracellular Vesicles Derived from Osteogenic-Differentiated Human Bone Marrow-Derived Mesenchymal Cells Rescue Osteogenic Ability of Bone Marrow-Derived Mesenchymal Cells Impaired by Hypoxia. Biomedicines 11 (10), S. 2804.

Wank, Isabel, Niedermair, Tanja, Kronenberg, Daniel, Stange, Richard, Brochhausen, Christoph

, Hess, Andreas und Grässel, Susanne

(2022) Influence of the Peripheral Nervous System on Murine Osteoporotic Fracture Healing and Fracture-Induced Hyperalgesia. International Journal of Molecular Sciences 24 (1), S. 510.

Stöckl, Sabine, Reichart, Johanna, Zborilova, Magdalena, Johnstone, Brian und Grässel, Susanne

(2022) Semaphorin 3A-Neuropilin-1 Signaling Modulates MMP13 Expression in Human Osteoarthritic Chondrocytes. International Journal of Molecular Sciences 23 (22), S. 14180.

Wang, Chenglong, Stöckl, Sabine, Li, Shushan, Herrmann, Marietta, Lukas, Christoph, Reinders, Yvonne, Sickmann, Albert und Grässel, Susanne

(2022) Effects of Extracellular Vesicles from Osteogenic Differentiated Human BMSCs on Osteogenic and Adipogenic Differentiation Capacity of Naïve Human BMSCs. Cells 11 (16), S. 2491.

Rösch, Gundula, Muschter, Dominique, Taheri, Shahed

, El Bagdadi, Karima, Dorn, Christoph, Meurer, Andrea, Zaucke, Frank, Schilling, Arndt F., Grässel, Susanne, Straub, Rainer H. und Jenei-Lanzl, Zsuzsa

(2022) β2-Adrenoceptor Deficiency Results in Increased Calcified Cartilage Thickness and Subchondral Bone Remodeling in Murine Experimental Osteoarthritis. Frontiers in Immunology 12.

Schäfer, Nicole und Grässel, Susanne (2022) Involvement of complement peptides C3a and C5a in osteoarthritis pathology. Peptides 154, S. 170815. Volltext nicht vorhanden.

Fleischhauer, Lutz

, Muschter, Dominique, Farkas, Zsuzsanna, Grässel, Susanne, Aszodi, Attila

, Clausen-Schaumann, Hauke

und Alberton, Paolo

(2022) Nano-Scale Mechanical Properties of the Articular Cartilage Zones in a Mouse Model of Post-Traumatic Osteoarthritis. Applied Sciences 12 (5), S. 2596. Volltext nicht vorhanden.

Rösch, Gundula, El Bagdadi, Karima, Muschter, Dominique

, Taheri, Shahed, Dorn, Christoph

, Meurer, Andrea, Straub, Rainer H.

, Zaucke, Frank

, Schilling, Arndt F., Grässel, Susanne

und Jenei-Lanzl, Zsuzsa (2021) Sympathectomy aggravates subchondral bone changes during osteoarthritis progression in mice without affecting cartilage degeneration or synovial inflammation. Osteoarthritis and Cartilage 30 (3), S. 461-474. Volltext nicht vorhanden.

Grässel, Susanne

, Eitner, Annett, Bauer, Richard J., König, Matthias, Johnstone, Brian und Stöckl, Sabine (2021) Substance P and Alpha-Calcitonin Gene-Related Peptide Differentially Affect Human Osteoarthritic and Healthy Chondrocytes. Frontiers in Immunology 12 (722884), S. 1-16. (Eingereicht)

Nazet, Ute

, Neubert, Patrick, Schatz, Valentin, Grässel, Susanne

, Proff, Peter

, Jantsch, Jonathan, Schröder, Agnes

und Kirschneck, Christian

(2021) Differential gene expression response of synovial fibroblasts from temporomandibular joints and knee joints to dynamic tensile stress. Journal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie.

Grässel, Susanne

, Zaucke, Frank

und Madry, Henning

(2021) Osteoarthritis: Novel Molecular Mechanisms Increase Our Understanding of the Disease Pathology. Journal of Clinical Medicine 10 (9), S. 1938.

Li, Shushan, Stöckl, Sabine, Lukas, Christoph, Herrmann, Marietta

, Brochhausen, Christoph

, König, Matthias A., Johnstone, Brian

und Grässel, Susanne

(2021) Curcumin-primed human BMSC-derived extracellular vesicles reverse IL-1β-induced catabolic responses of OA chondrocytes by upregulating miR-126-3p. Stem Cell Research & Therapy 12 (1), S. 252.

Nazet, Ute

, Feulner, Laura, Muschter, Dominique

, Neubert, Patrick, Schatz, Valentin, Grässel, Susanne

, Jantsch, Jonathan, Proff, Peter, Schröder, Agnes

und Kirschneck, Christian

(2021) Mechanical stress induce PG-E2 in murine synovial fibroblasts originating from the temporomandibular joint. Cells 2021 (10), S. 298. (Eingereicht)

Herrmann, Marietta, Diederichs, Solvig

, Melnik, Svitlana, Riegger, Jana

, Trivanović, Drenka, Li, Shushan, Jenei-Lanzl, Zsuzsa, Brenner, Rolf E., Huber-Lang, Markus, Zaucke, Frank, Schildberg, Frank A. und Grässel, Susanne (2021) Extracellular Vesicles in Musculoskeletal Pathologies and Regeneration. Frontiers in Bioengineering and Biotechnology 8. Volltext nicht vorhanden.

Nazet, Ute, Feulner, Laura, Muschter, Dominique, Neubert, Patrick, Schatz, Valentin, Grässel, Susanne, Jantsch, Jonathan, Proff, Peter, Schröder, Agnes und Kirschneck, Christian (2021) Mechanical Stress Induce PG-E2 in Murine Synovial Fibroblasts Originating from the Temporomandibular Joint. Cells 10 (2), S. 298. Volltext nicht vorhanden.

Grässel, Susanne

, Zaucke, Frank

und Madry, Henning

(2021) Osteoarthritis: Novel Molecular Mechanisms Increase Our Understanding of the Disease Pathology. Journal of Clinical Medicine 10 (9), S. 1938. Volltext nicht vorhanden.

Madry, Henning, Grässel, Susanne, Nöth, Ulrich, Relja, Borna

, Bernstein, Anke, Docheva, Denitsa

, Kauther, Max Daniel, Katthagen, Jan Christoph, Bader, Rainer, van Griensven, Martijn

, Wirtz, Dieter C., Raschke, Michael J. und Huber-Lang, Markus (2021) The future of basic science in orthopaedics and traumatology: Cassandra or Prometheus? European Journal of Medical Research 26 (1). Volltext nicht vorhanden.

Niedermair, Tanja, Lukas, Christoph, Li, Shushan

, Stöckl, Sabine, Craiovan, Benjamin, Brochhausen, Christoph

, Federlin, Marianne, Herrmann, Marietta und Grässel, Susanne

(2020) Influence of Extracellular Vesicles Isolated From Osteoblasts of Patients With Cox-Arthrosis and/or Osteoporosis on Metabolism and Osteogenic Differentiation of BMSCs. Frontiers in Bioengineering and Biotechnology 8 (615520), S. 1-15.

Li, Shushan, Stöckl, Sabine, Lukas, Christoph, Götz, Julia, Herrmann, Marietta, Federlin, Marianne und Grässel, Susanne (2020) hBMSC-Derived Extracellular Vesicles Attenuate IL-1β-Induced Catabolic Effects on OA-Chondrocytes by Regulating Pro-inflammatory Signaling Pathways. Frontiers in Bioengineering and Biotechnology 8 (603598), S. 1-24.

Stöckl, Sabine, Lindner, Georg, Li, Shushan

, Schuster, Philipp, Haferkamp, Sebastian, Wagner, Ferdinand, Prodinger, Peter M., Multhoff, Gabriele, Boxberg, Melanie, Hillmann, Axel, Bauer, Richard J. und Grässel, Susanne

(2020) SOX9 Knockout Induces Polyploidy and Changes Sensitivity to Tumor Treatment Strategies in a Chondrosarcoma Cell Line. International Journal of Molecular Sciences 21 (20), S. 7627.

Nazet, Ute, Grässel, Susanne, Jantsch, Jonathan, Proff, Peter, Schröder, Agnes und Kirschneck, Christian

(2020) Early OA Stage Like Response Occurs after Dynamic Stretching of Human Synovial Fibroblasts. International Journal of Molecular Sciences 21 (11), S. 3874.

Niedermair, Tanja, Straub, Rainer H.

, Brochhausen, Christoph und Grässel, Susanne

(2020) Impact of the Sensory and Sympathetic Nervous System on Fracture Healing in Ovariectomized Mice. International Journal of Molecular Sciences 21 (405), S. 1-18.

Niedermair, Tanja, Schirner, Stephan, Lasheras, Mar Guaza, Straub, Rainer H.

und Grässel, Susanne (2020) Absence of α-calcitonin gene-related peptide modulates bone remodeling properties of murine osteoblasts and osteoclasts in an age-dependent way. Mechanisms of Ageing and Development 189, S. 111265. Volltext nicht vorhanden.

Niedermair, Tanja, Straub, Rainer H.

, Brochhausen, Christoph und Grässel, Susanne

(2020) Impact of the Sensory and Sympathetic Nervous System on Fracture Healing in Ovariectomized Mice. International Journal of Molecular Sciences 21, S. 405.

Hedderich, Jessica, El Bagdadi, Karima, Angele, Peter, Grässel, Susanne, Meurer, Andrea, Straub, Rainer H.

, Zaucke, Frank

und Jenei-Lanzl, Zsuzsa (2020) Norepinephrine Inhibits the Proliferation of Human Bone Marrow-Derived Mesenchymal Stem Cells via β2-Adrenoceptor-Mediated ERK1/2 and PKA Phosphorylation. International Journal of Molecular Sciences 21 (11), S. 3924. Volltext nicht vorhanden.

Muschter, Dominique, Fleischhauer, Lutz

, Taheri, Shahed, Schilling, Arndt F., Clausen-Schaumann, Hauke

und Grässel, Susanne (2020) Sensory neuropeptides are required for bone and cartilage homeostasis in a murine destabilization-induced osteoarthritis model. Bone 133, S. 115181. Volltext nicht vorhanden.

Nazet, Ute

, Schröder, Agnes, Grässel, Susanne

, Muschter, Dominique

, Proff, Peter und Kirschneck, Christian

(2019) Housekeeping gene validation for RT-qPCR studies on synovial fibroblasts derived from healthy and osteoarthritic patients with focus on mechanical loading. PLOS ONE 14 (12), e0225790.

Schröder, Agnes, Nazet, Ute, Muschter, Dominique, Grässel, Susanne

, Proff, Peter und Kirschneck, Christian

(2019) Impact of Mechanical Load on the Expression Profile of Synovial Fibroblasts from Patients with and without Osteoarthritis. International Journal of Molecular Sciences 20 (3), S. 585.

Wagner, Ferdinand, Holzapfel, Boris M., Martine, Laure C., McGovern, Jacqui, Lahr, Christoph A., Boxberg, Melanie, Prodinger, Peter M., Grässel, Susanne, Loessner, Daniela und Hutmacher, Dietmar W.

(2019) A humanized bone microenvironment uncovers HIF2 alpha as a latent marker for osteosarcoma. Acta Biomaterialia 89, S. 372-381. Volltext nicht vorhanden.

Wessely, Anja

, Waltera, Anna, Reichert, Torsten E., Stöckl, Sabine, Grässel, Susanne und Bauer, Richard J. (2019) Induction of ALP and MMP9 activity facilitates invasive behavior in heterogeneous human BMSC and HNSCC 3D spheroids. The FASEB Journal 33 (11), S. 11884-11893. Volltext nicht vorhanden.

Grässel, Susanne

und Aszodi, A. (2019) Osteoarthritis and Cartilage Regeneration: Focus on Pathophysiology and Molecular Mechanisms. International Journal of Molecular Sciences 20 (24), S. 6156.

Muschter, Dominique, Beiderbeck, Anna-Sophie, Späth, Tanja, Kirschneck, Christian

, Schröder, Agnes und Grässel, Susanne

(2019) Sensory Neuropeptides and their Receptors Participate in Mechano-Regulation of Murine Macrophages. International Journal of Molecular Sciences 20, S. 503. Volltext nicht vorhanden.

Niedermair, Tanja, Schirner, Stephan, Seebröker, Raphael, Straub, Rainer H.

und Grässel, Susanne (2018) Substance P modulates bone remodeling properties of murine osteoblasts and osteoclasts. Scientific Reports 8 (9199), S. 1-15.

Grässel, Susanne und Muschter, Dominique (2018) Do Neuroendocrine Peptides and Their Receptors Qualify as Novel Therapeutic Targets in Osteoarthritis? International Journal of Molecular Sciences 19 (2), S. 367.

Mayer, Ute, Benditz, Achim und Grässel, Susanne (2017) miR-29b regulates expression of collagens I and III in chondrogenically differentiating BMSC in an osteoarthritic environment. Scientific Reports 7 (13297), S. 1-14.

Hildebrand, Frank, Grässel, Susanne, Marzi, Ingo, Meurer, Andrea, Nerlich, Michael und Loibl, Markus (2017) Kooperation der Deutschen Gesellschaft für Orthopädie und Unfallchirurgie (DGOU) und der Orthopaedic Research Society (ORS). Zeitschrift für Orthopädie und Unfallchirurgie 155 (05), S. 515-516. Volltext nicht vorhanden.

Grässel, Susanne

und Muschter, Dominique

(2017) Peripheral Nerve Fibers and Their Neurotransmitters in Osteoarthritis Pathology. International Journal of Molecular Sciences 18, S. 931.

Böhm, Markus, Apel, Mara, Lowin, Torsten, Lorenz, Julia, Jenei-Lanzl, Zsuzsa, Capellino, Silvia

, Dosoki, Heba, Luger, Thomas A., Straub, Rainer H. und Grässel, Susanne (2016) α-MSH modulates cell adhesion and inflammatory responses of synovial fibroblasts from osteoarthritis patients. Biochemical Pharmacology 116, S. 89-99. Volltext nicht vorhanden.

Grässel, Susanne, Muschter, Dominique, Schäfer, Nicole, Stangl, Hubert und Straub, Rainer H. (2015) Sympathetic Neurotransmitters Modulate Osteoclastogenesis and Osteoclast Activity in the Context of Collagen-Induced Arthritis. PLoS ONE 2015 (10), e0139726.

Grässel, Susanne, Mutscher, Dominique, Göttl, Claudia, Vogel, Mandy, Grifka, Joachim und Straub, Rainer H. (2015) Reactivity of rat bone marrow-derived macrophages to neurotransmitter stimulation in the context of collagen II-induced arthritis. Arthritis Research & Therapy 17 (169), S. 1-15.

Leyh, Michaela, Seitz, Andreas, Dürselen, Lutz, Schaumburger, Jens, Ignatius, Anita, Grifka, Joachim und Grässel, Susanne (2014) Subchondral bone influences chondrogenic differentiation and collagen production of human bone marrow-derived mesenchymal stem cells and articular chondrocytes. Arthritis Research & Therapy 16 (453).

Lorenz, Julia, Seebach, Elisabeth, Hackmeyer, Gerit, Greth, Carina, Bauer, Richard J., Kleinschmidt, Kerstin, Bettenworth, Dominik, Böhm, Markus, Grifka, Joachim und Grässel, Susanne (2014) Melanocortin 1 receptor-signaling deficiency results in an articular cartilage phenotype and accelerates pathogenesis of surgically induced murine osteoarthritis. PLOS ONE 9 (9), e105858.

Lehy, Michaela, Seitz, Andreas, Dürselen, Lutz, Springorum, Hans-Robert, Angele, Peter, Ignatius, Anita, Grifka, Joachim und Grässel, Susanne (2014) Osteoarthritic cartilage explants affect extracellular matrix production and composition in cocultured bone marrow-derived mesenchymal stem cells and articular chondrocytes. Stem Cell Research & therapy 5 (3).

Bedal, Konstanze B., Grässel, Susanne, Oefner, Peter J., Reinders, Jörg, Reichert, Torsten E. und Bauer, Richard (2014) Collagen XVI induces expression of MMP9 via modulation of AP-1 transcription factors and facilitates invasion of oral squamous cell carcinoma. Plos One 9 (1), e86777.

Pongratz, Georg, Anthofer, Judith M., Melzer, Madlen, Anders, Sven, Grässel, Susanne und Straub, Rainer H.

(2013) IL-7 receptor α expressing B cells act proinflammatory in collagen-induced arthritis and are inhibited by sympathetic neurotransmitters. Annals of the Rheumatic Diseases 73, S. 306-312.

Stöckl, Sabine, Göttl, Claudia, Grifka, Joachim und Grässel, Susanne

(2013) Sox9 Modulates Proliferation and Expression of Osteogenic Markers of Adipose-Derived Stem Cells (ASC). Cell. Physiol. Biochem. 31, S. 703-717.

Bauer, Richard, Ratzinger, Sabine, Wales, Lynn, Bosserhoff, Anja, Senner, V., Grifka, Joachim und Grässel, Susanne

(2011) Inhibition of Collagen XVI Expression Reduces Glioma Cell Invasiveness. Cellular Physiology and Biochemistry 27, S. 217-226.

Lechler, Philipp, Balakrishnan, Sanjeevi, Schaumburger, Jens, Grässel, Susanne, Baier, Clemens, Grifka, Joachim, Straub, Rainer H. und Renkawitz, Tobias (2011) The oncofetal gene survivin is re-expressed in osteoarthritis and is required for chondrocyte proliferation in vitro. BMC musculoskeletal disorders 12, S. 150.

Radons, Jürgen, Bosserhoff, Anja Katrin, Grässel, Susanne, Falk, Werner und Schubert, Thomas E. O. (2006) p38MAPK mediates IL-1-induced down-regulation of aggrecan gene expression in human chondrocytes. International journal of molecular medicine 17 (4), S. 661-668. Zugang zum Volltext eingeschränkt.

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