Entries of Grässel, Susanne on the publication server

Ehrnsperger, Marianne, Taheri, Shahed, Pann, Patrick, Schilling, Arndt F. and Grässel, Susanne (2024) Differential effects of alendronate on chondrocytes, cartilage matrix and subchondral bone structure in surgically induced osteoarthritis in mice. Scientific Reports 14, p. 25026.

Wang, Chenglong, Stöckl, Sabine, Pattappa, Girish , Schulz, Daniela , Hofmann, Korbinian, Ilic, Jovana, Reinders, Yvonne, Bauer, Richard J. , Sickmann, Albert and Grässel, Susanne (2023) Extracellular Vesicles Derived from Osteogenic-Differentiated Human Bone Marrow-Derived Mesenchymal Cells Rescue Osteogenic Ability of Bone Marrow-Derived Mesenchymal Cells Impaired by Hypoxia. Biomedicines 11 (10), p. 2804.

Wank, Isabel, Niedermair, Tanja, Kronenberg, Daniel, Stange, Richard, Brochhausen, Christoph , Hess, Andreas and Grässel, Susanne (2022) Influence of the Peripheral Nervous System on Murine Osteoporotic Fracture Healing and Fracture-Induced Hyperalgesia. International Journal of Molecular Sciences 24 (1), p. 510.

Stöckl, Sabine, Reichart, Johanna, Zborilova, Magdalena, Johnstone, Brian and Grässel, Susanne (2022) Semaphorin 3A-Neuropilin-1 Signaling Modulates MMP13 Expression in Human Osteoarthritic Chondrocytes. International Journal of Molecular Sciences 23 (22), p. 14180.

Wang, Chenglong, Stöckl, Sabine, Li, Shushan, Herrmann, Marietta, Lukas, Christoph, Reinders, Yvonne, Sickmann, Albert and Grässel, Susanne (2022) Effects of Extracellular Vesicles from Osteogenic Differentiated Human BMSCs on Osteogenic and Adipogenic Differentiation Capacity of Naïve Human BMSCs. Cells 11 (16), p. 2491.

Rösch, Gundula, Muschter, Dominique, Taheri, Shahed , El Bagdadi, Karima, Dorn, Christoph, Meurer, Andrea, Zaucke, Frank, Schilling, Arndt F., Grässel, Susanne, Straub, Rainer H. and Jenei-Lanzl, Zsuzsa (2022) β2-Adrenoceptor Deficiency Results in Increased Calcified Cartilage Thickness and Subchondral Bone Remodeling in Murine Experimental Osteoarthritis. Frontiers in Immunology 12.

Schäfer, Nicole and Grässel, Susanne (2022) Involvement of complement peptides C3a and C5a in osteoarthritis pathology. Peptides 154, p. 170815. Fulltext not available.

Fleischhauer, Lutz , Muschter, Dominique, Farkas, Zsuzsanna, Grässel, Susanne, Aszodi, Attila , Clausen-Schaumann, Hauke and Alberton, Paolo (2022) Nano-Scale Mechanical Properties of the Articular Cartilage Zones in a Mouse Model of Post-Traumatic Osteoarthritis. Applied Sciences 12 (5), p. 2596. Fulltext not available.

Rösch, Gundula, El Bagdadi, Karima, Muschter, Dominique , Taheri, Shahed, Dorn, Christoph , Meurer, Andrea, Straub, Rainer H. , Zaucke, Frank , Schilling, Arndt F., Grässel, Susanne and Jenei-Lanzl, Zsuzsa (2021) Sympathectomy aggravates subchondral bone changes during osteoarthritis progression in mice without affecting cartilage degeneration or synovial inflammation. Osteoarthritis and Cartilage 30 (3), pp. 461-474. Fulltext not available.

Grässel, Susanne , Eitner, Annett, Bauer, Richard J., König, Matthias, Johnstone, Brian and Stöckl, Sabine (2021) Substance P and Alpha-Calcitonin Gene-Related Peptide Differentially Affect Human Osteoarthritic and Healthy Chondrocytes. Frontiers in Immunology 12 (722884), pp. 1-16. (Submitted)

Nazet, Ute , Neubert, Patrick, Schatz, Valentin, Grässel, Susanne , Proff, Peter , Jantsch, Jonathan, Schröder, Agnes and Kirschneck, Christian (2021) Differential gene expression response of synovial fibroblasts from temporomandibular joints and knee joints to dynamic tensile stress. Journal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie.

Grässel, Susanne , Zaucke, Frank and Madry, Henning (2021) Osteoarthritis: Novel Molecular Mechanisms Increase Our Understanding of the Disease Pathology. Journal of Clinical Medicine 10 (9), p. 1938.

Li, Shushan, Stöckl, Sabine, Lukas, Christoph, Herrmann, Marietta , Brochhausen, Christoph , König, Matthias A., Johnstone, Brian and Grässel, Susanne (2021) Curcumin-primed human BMSC-derived extracellular vesicles reverse IL-1β-induced catabolic responses of OA chondrocytes by upregulating miR-126-3p. Stem Cell Research & Therapy 12 (1), p. 252.

Nazet, Ute , Feulner, Laura, Muschter, Dominique , Neubert, Patrick, Schatz, Valentin, Grässel, Susanne , Jantsch, Jonathan, Proff, Peter, Schröder, Agnes and Kirschneck, Christian (2021) Mechanical stress induce PG-E2 in murine synovial fibroblasts originating from the temporomandibular joint. Cells 2021 (10), p. 298. (Submitted)

Herrmann, Marietta, Diederichs, Solvig , Melnik, Svitlana, Riegger, Jana , Trivanović, Drenka, Li, Shushan, Jenei-Lanzl, Zsuzsa, Brenner, Rolf E., Huber-Lang, Markus, Zaucke, Frank, Schildberg, Frank A. and Grässel, Susanne (2021) Extracellular Vesicles in Musculoskeletal Pathologies and Regeneration. Frontiers in Bioengineering and Biotechnology 8. Fulltext not available.

Nazet, Ute, Feulner, Laura, Muschter, Dominique, Neubert, Patrick, Schatz, Valentin, Grässel, Susanne, Jantsch, Jonathan, Proff, Peter, Schröder, Agnes and Kirschneck, Christian (2021) Mechanical Stress Induce PG-E2 in Murine Synovial Fibroblasts Originating from the Temporomandibular Joint. Cells 10 (2), p. 298. Fulltext not available.

Grässel, Susanne , Zaucke, Frank and Madry, Henning (2021) Osteoarthritis: Novel Molecular Mechanisms Increase Our Understanding of the Disease Pathology. Journal of Clinical Medicine 10 (9), p. 1938. Fulltext not available.

Madry, Henning, Grässel, Susanne, Nöth, Ulrich, Relja, Borna , Bernstein, Anke, Docheva, Denitsa , Kauther, Max Daniel, Katthagen, Jan Christoph, Bader, Rainer, van Griensven, Martijn , Wirtz, Dieter C., Raschke, Michael J. and Huber-Lang, Markus (2021) The future of basic science in orthopaedics and traumatology: Cassandra or Prometheus? European Journal of Medical Research 26 (1). Fulltext not available.

Niedermair, Tanja, Lukas, Christoph, Li, Shushan , Stöckl, Sabine, Craiovan, Benjamin, Brochhausen, Christoph , Federlin, Marianne, Herrmann, Marietta and Grässel, Susanne (2020) Influence of Extracellular Vesicles Isolated From Osteoblasts of Patients With Cox-Arthrosis and/or Osteoporosis on Metabolism and Osteogenic Differentiation of BMSCs. Frontiers in Bioengineering and Biotechnology 8 (615520), pp. 1-15.

Li, Shushan, Stöckl, Sabine, Lukas, Christoph, Götz, Julia, Herrmann, Marietta, Federlin, Marianne and Grässel, Susanne (2020) hBMSC-Derived Extracellular Vesicles Attenuate IL-1β-Induced Catabolic Effects on OA-Chondrocytes by Regulating Pro-inflammatory Signaling Pathways. Frontiers in Bioengineering and Biotechnology 8 (603598), pp. 1-24.

Stöckl, Sabine, Lindner, Georg, Li, Shushan , Schuster, Philipp, Haferkamp, Sebastian, Wagner, Ferdinand, Prodinger, Peter M., Multhoff, Gabriele, Boxberg, Melanie, Hillmann, Axel, Bauer, Richard J. and Grässel, Susanne (2020) SOX9 Knockout Induces Polyploidy and Changes Sensitivity to Tumor Treatment Strategies in a Chondrosarcoma Cell Line. International Journal of Molecular Sciences 21 (20), p. 7627.

Nazet, Ute, Grässel, Susanne, Jantsch, Jonathan, Proff, Peter, Schröder, Agnes and Kirschneck, Christian (2020) Early OA Stage Like Response Occurs after Dynamic Stretching of Human Synovial Fibroblasts. International Journal of Molecular Sciences 21 (11), p. 3874.

Niedermair, Tanja, Straub, Rainer H. , Brochhausen, Christoph and Grässel, Susanne (2020) Impact of the Sensory and Sympathetic Nervous System on Fracture Healing in Ovariectomized Mice. International Journal of Molecular Sciences 21 (405), pp. 1-18.

Niedermair, Tanja, Schirner, Stephan, Lasheras, Mar Guaza, Straub, Rainer H. and Grässel, Susanne (2020) Absence of α-calcitonin gene-related peptide modulates bone remodeling properties of murine osteoblasts and osteoclasts in an age-dependent way. Mechanisms of Ageing and Development 189, p. 111265. Fulltext not available.

Niedermair, Tanja, Straub, Rainer H. , Brochhausen, Christoph and Grässel, Susanne (2020) Impact of the Sensory and Sympathetic Nervous System on Fracture Healing in Ovariectomized Mice. International Journal of Molecular Sciences 21, p. 405.

Hedderich, Jessica, El Bagdadi, Karima, Angele, Peter, Grässel, Susanne, Meurer, Andrea, Straub, Rainer H. , Zaucke, Frank and Jenei-Lanzl, Zsuzsa (2020) Norepinephrine Inhibits the Proliferation of Human Bone Marrow-Derived Mesenchymal Stem Cells via β2-Adrenoceptor-Mediated ERK1/2 and PKA Phosphorylation. International Journal of Molecular Sciences 21 (11), p. 3924. Fulltext not available.

Muschter, Dominique, Fleischhauer, Lutz , Taheri, Shahed, Schilling, Arndt F., Clausen-Schaumann, Hauke and Grässel, Susanne (2020) Sensory neuropeptides are required for bone and cartilage homeostasis in a murine destabilization-induced osteoarthritis model. Bone 133, p. 115181. Fulltext not available.

Nazet, Ute , Schröder, Agnes, Grässel, Susanne , Muschter, Dominique , Proff, Peter and Kirschneck, Christian (2019) Housekeeping gene validation for RT-qPCR studies on synovial fibroblasts derived from healthy and osteoarthritic patients with focus on mechanical loading. PLOS ONE 14 (12), e0225790.

Schröder, Agnes, Nazet, Ute, Muschter, Dominique, Grässel, Susanne , Proff, Peter and Kirschneck, Christian (2019) Impact of Mechanical Load on the Expression Profile of Synovial Fibroblasts from Patients with and without Osteoarthritis. International Journal of Molecular Sciences 20 (3), p. 585.

Wagner, Ferdinand, Holzapfel, Boris M., Martine, Laure C., McGovern, Jacqui, Lahr, Christoph A., Boxberg, Melanie, Prodinger, Peter M., Grässel, Susanne, Loessner, Daniela and Hutmacher, Dietmar W. (2019) A humanized bone microenvironment uncovers HIF2 alpha as a latent marker for osteosarcoma. Acta Biomaterialia 89, pp. 372-381. Fulltext not available.

Wessely, Anja , Waltera, Anna, Reichert, Torsten E., Stöckl, Sabine, Grässel, Susanne and Bauer, Richard J. (2019) Induction of ALP and MMP9 activity facilitates invasive behavior in heterogeneous human BMSC and HNSCC 3D spheroids. The FASEB Journal 33 (11), pp. 11884-11893. Fulltext not available.

Grässel, Susanne and Aszodi, A. (2019) Osteoarthritis and Cartilage Regeneration: Focus on Pathophysiology and Molecular Mechanisms. International Journal of Molecular Sciences 20 (24), p. 6156.

Muschter, Dominique, Beiderbeck, Anna-Sophie, Späth, Tanja, Kirschneck, Christian , Schröder, Agnes and Grässel, Susanne (2019) Sensory Neuropeptides and their Receptors Participate in Mechano-Regulation of Murine Macrophages. International Journal of Molecular Sciences 20, p. 503. Fulltext not available.

Niedermair, Tanja, Schirner, Stephan, Seebröker, Raphael, Straub, Rainer H. and Grässel, Susanne (2018) Substance P modulates bone remodeling properties of murine osteoblasts and osteoclasts. Scientific Reports 8 (9199), pp. 1-15.

Grässel, Susanne and Muschter, Dominique (2018) Do Neuroendocrine Peptides and Their Receptors Qualify as Novel Therapeutic Targets in Osteoarthritis? International Journal of Molecular Sciences 19 (2), p. 367.

Mayer, Ute, Benditz, Achim and Grässel, Susanne (2017) miR-29b regulates expression of collagens I and III in chondrogenically differentiating BMSC in an osteoarthritic environment. Scientific Reports 7 (13297), pp. 1-14.

Hildebrand, Frank, Grässel, Susanne, Marzi, Ingo, Meurer, Andrea, Nerlich, Michael and Loibl, Markus (2017) Kooperation der Deutschen Gesellschaft für Orthopädie und Unfallchirurgie (DGOU) und der Orthopaedic Research Society (ORS). Zeitschrift für Orthopädie und Unfallchirurgie 155 (05), pp. 515-516. Fulltext not available.

Grässel, Susanne and Muschter, Dominique (2017) Peripheral Nerve Fibers and Their Neurotransmitters in Osteoarthritis Pathology. International Journal of Molecular Sciences 18, p. 931.

Böhm, Markus, Apel, Mara, Lowin, Torsten, Lorenz, Julia, Jenei-Lanzl, Zsuzsa, Capellino, Silvia , Dosoki, Heba, Luger, Thomas A., Straub, Rainer H. and Grässel, Susanne (2016) α-MSH modulates cell adhesion and inflammatory responses of synovial fibroblasts from osteoarthritis patients. Biochemical Pharmacology 116, pp. 89-99. Fulltext not available.

Grässel, Susanne, Muschter, Dominique, Schäfer, Nicole, Stangl, Hubert and Straub, Rainer H. (2015) Sympathetic Neurotransmitters Modulate Osteoclastogenesis and Osteoclast Activity in the Context of Collagen-Induced Arthritis. PLoS ONE 2015 (10), e0139726.

Grässel, Susanne, Mutscher, Dominique, Göttl, Claudia, Vogel, Mandy, Grifka, Joachim and Straub, Rainer H. (2015) Reactivity of rat bone marrow-derived macrophages to neurotransmitter stimulation in the context of collagen II-induced arthritis. Arthritis Research & Therapy 17 (169), pp. 1-15.

Leyh, Michaela, Seitz, Andreas, Dürselen, Lutz, Schaumburger, Jens, Ignatius, Anita, Grifka, Joachim and Grässel, Susanne (2014) Subchondral bone influences chondrogenic differentiation and collagen production of human bone marrow-derived mesenchymal stem cells and articular chondrocytes. Arthritis Research & Therapy 16 (453).

Lorenz, Julia, Seebach, Elisabeth, Hackmeyer, Gerit, Greth, Carina, Bauer, Richard J., Kleinschmidt, Kerstin, Bettenworth, Dominik, Böhm, Markus, Grifka, Joachim and Grässel, Susanne (2014) Melanocortin 1 receptor-signaling deficiency results in an articular cartilage phenotype and accelerates pathogenesis of surgically induced murine osteoarthritis. PLOS ONE 9 (9), e105858.

Lehy, Michaela, Seitz, Andreas, Dürselen, Lutz, Springorum, Hans-Robert, Angele, Peter, Ignatius, Anita, Grifka, Joachim and Grässel, Susanne (2014) Osteoarthritic cartilage explants affect extracellular matrix production and composition in cocultured bone marrow-derived mesenchymal stem cells and articular chondrocytes. Stem Cell Research & therapy 5 (3).

Bedal, Konstanze B., Grässel, Susanne, Oefner, Peter J., Reinders, Jörg, Reichert, Torsten E. and Bauer, Richard (2014) Collagen XVI induces expression of MMP9 via modulation of AP-1 transcription factors and facilitates invasion of oral squamous cell carcinoma. Plos One 9 (1), e86777.

Pongratz, Georg, Anthofer, Judith M., Melzer, Madlen, Anders, Sven, Grässel, Susanne and Straub, Rainer H. (2013) IL-7 receptor α expressing B cells act proinflammatory in collagen-induced arthritis and are inhibited by sympathetic neurotransmitters. Annals of the Rheumatic Diseases 73, pp. 306-312.

Stöckl, Sabine, Göttl, Claudia, Grifka, Joachim and Grässel, Susanne (2013) Sox9 Modulates Proliferation and Expression of Osteogenic Markers of Adipose-Derived Stem Cells (ASC). Cell. Physiol. Biochem. 31, pp. 703-717.

Bauer, Richard, Ratzinger, Sabine, Wales, Lynn, Bosserhoff, Anja, Senner, V., Grifka, Joachim and Grässel, Susanne (2011) Inhibition of Collagen XVI Expression Reduces Glioma Cell Invasiveness. Cellular Physiology and Biochemistry 27, pp. 217-226.

Lechler, Philipp, Balakrishnan, Sanjeevi, Schaumburger, Jens, Grässel, Susanne, Baier, Clemens, Grifka, Joachim, Straub, Rainer H. and Renkawitz, Tobias (2011) The oncofetal gene survivin is re-expressed in osteoarthritis and is required for chondrocyte proliferation in vitro. BMC musculoskeletal disorders 12, p. 150.

Radons, Jürgen, Bosserhoff, Anja Katrin, Grässel, Susanne, Falk, Werner and Schubert, Thomas E. O. (2006) p38MAPK mediates IL-1-induced down-regulation of aggrecan gene expression in human chondrocytes. International journal of molecular medicine 17 (4), pp. 661-668. Fulltext restricted.