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Number of items: 69.

2015

Lippert, Elisabeth, Stieber-Gunckel, Manuela, Dunger, Nadja, Falk, Werner, Obermeier, Florian and Kunst, Claudia (2015) Galectin-3 Modulates Experimental Colitis. Digestion 92 (1), pp. 45-53.

Radons, Jürgen, Falk, Werner and Dove, Stefan (2015) Identification of critical regions within the TIR domain of IL-1 receptor type I. The international journal of biochemistry & cell biology 68, pp. 15-20. Fulltext not available.

2006

Radons, Jürgen, Bosserhoff, Anja Katrin, Grässel, Susanne, Falk, Werner and Schubert, Thomas E. O. (2006) p38MAPK mediates IL-1-induced down-regulation of aggrecan gene expression in human chondrocytes. International journal of molecular medicine 17 (4), pp. 661-668. Fulltext restricted.

Radons, Jürgen, Falk, Werner and Schubert, Thomas E. O. (2006) Interleukin-10 does not affect IL-1-induced interleukin-6 and metalloproteinase production in human chondrosarcoma cells, SW1353. International journal of molecular medicine 17 (2), pp. 377-383. Fulltext restricted.

2003

Radons, Jürgen, Dove, Stefan, Neumann, D., Altmann, R., Botzki, Alexander, Martin, M.U. and Falk, Werner (2003) The IL-1 receptor accessory protein TIR domain: analysis of putative interaction sites by in-vitro mutagenesis and molecular modeling. The Journal of Biological Chemistry 278 (49), pp. 49145-49153. Fulltext not available.

1994

Falk, Werner, Stricker, K., Praast, G., Tsukitani, Y., Krammer, P. H. and Stoeck, M. (1994) Activation of the mouse IL-2 gene by okadaic acid: synergy with interleukin-1. Lymphokine and cytokine research 13 (3), pp. 167-174.

Männel, D. N., Orosz, P., Hafner, M. and Falk, Werner (1994) Mechanisms involved in metastasis enhanced by inflammatory mediators. Circulatory shock 44 (1), pp. 9-13.

1993

Stricker, K., Serfling, E., Krammer, P. H. and Falk, Werner (1993) An NF-kappa B-like element plays an essential role in interleukin-1-mediated costimulation of the mouse interleukin-2 promoter. European journal of immunology 23 (7), pp. 1475-1480.

Orosz, P., Echtenacher, Bernd, Falk, Werner, Rüschoff, J., Weber, D. and Männel, Daniela N. (1993) Enhancement of experimental metastasis by tumor necrosis factor. The Journal of experimental medicine 177 (5), pp. 1391-1398.

Echtenacher, B., Falk, Werner, Männel, D.N. and Krammer, P.H. (1993) Survival from cecal ligation and puncture and the formation of fibrous adhesions in the peritoneal cavity depend on endogenous tumor necrosis factor. In: Faist, E. and Meakins, J.L., (eds.) Host Defense Dysfunction in Trauma, Shock and Sepsis. Springer, Berlin u.a., pp. 755-758.

Männel, D.N., Orosz, P., Echtenacher, B., Rüschoff, J. and Falk, Werner (1993) Zytokine in der Tumor-Wirt-Interaktion. In: Wilmanns, W., (ed.) Zytokine. Thieme, Stuttgart, pp. 116-119.

1992

Oehm, A., Behrmann, I., Falk, Werner, Pawlita, M., Maier, G., Klas, C., Li-Weber, M., Richards, S., Dhein, J. and Trauth, B. C. (1992) Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen. The Journal of biological chemistry 267 (15), pp. 10709-10715.

Echtenacher, B., Falk, Werner, Männel, D.N. and Krammer, P.H. (1992) TNF in peritonitis of the mouse. In: Ullmann, U. and Dalhoff, A., (eds.) Significance of cytokines in the treatment of infectious deseases. Gustav Fischer, Stuttgart u.a.. Fulltext not available.

Männel, D.N., Jänicke, R., Westenfelder, U., Orosz, P.G., Echtenacher, B., Kist, A. and Falk, Werner (1992) Tumor cell-induced TNF production. In: Osawa, T. and Bonavida, B., (eds.) Tumor Necrosis Factor: Structure Function Relationship and Clinical Application. Karger, Basel, pp. 166-172.

1991

Krammer, P.H., Behrmann, I., Bier, V., Daniel, P., Dhein, J., Falk, M.H., Garcin, G., Klas, C., Knipping, E., Lücking-Famira, K.M., Matzku, S., Oehm, A., Richards, S., Trauth, B.C., Bornkamm, G.W., Falk, Werner, Möller, P. and Debatin, K.M. (1991) Apoptosis in the Apo-1 system. In: Tomei, J. and Cope, F., (eds.) Apoptosis: The Molecular Basis of Cell Death. Harbour Laboratory Press, Cold Spring, pp. 87-99.

Zawatzky, R., Wurmbaeck, H., Falk, Werner and Homfeld, A. (1991) Endogenous interferon specifically regulates Newcastle disease virus-induced cytokine gene expression in mouse macrophages. Journal of virology 65 (9), pp. 4839-4846.

1990

Lahm, H., Fischer, J. R., Reichert, Y., Hederer, R., Falk, Werner, Debatin, K. M. and Krammer, P. H. (1990) Autocrine growth factors secreted by the malignant human B-cell-line BJAB are distinct from other known cytokines. European cytokine network 1 (1), pp. 41-46. Fulltext not available.

Mannel, D. N., Falk, Werner and Yron, I. (1990) Inhibition of murine cytotoxic T cell responses by progesterone. Immunology letters 26 (1), pp. 89-94.

Falk, Werner, Albrecht, M.P., Stricker, K., Serfling, E. and Krammer, P.H. (1990) Internalization of IL-1 is required for IL-2 gene activation in EL4 thymoma cells. In: Oppenheim, J.J. and Powanda, M.C. and Kluger, M.J. and Cinarello, C.A., (eds.) Progress in Leukocyte Biology 10A: Molecular and Cellular biology of Cytokines. Wiley-Liss, New York u.a., pp. 191-196.

Echtenacher, B., Falk, Werner, Männel, D. N. and Krammer, P. H. (1990) Requirement of endogenous tumor necrosis factor/cachectin for recovery from experimental peritonitis. Journal of immunology (Baltimore, Md. : 1950) 145 (11), pp. 3762-3766.

Männel, D. N., Jänicke, R., Westenfelder, U., Echtenacher, B., Kist, A. and Falk, Werner (1990) Tumor-induced tumor necrosis factor production in macrophages. Lymphokine research 9 (4), pp. 485-489.

1989

Falk, Werner, Hoegen, I. von and Krammer, P.H. (1989) Activation of T cells by interleukin 1 involves internalization of interleukin 1. Lymphokine research 8 (3), pp. 263-268.

Krammer, P.H., Trauth, B.C., Bier, V., Dhein, J., Falk, Werner, Garcin, G., Klas, C., Müller, W., Oehm, A., Peters, A.M.J., Matzku, S., Möller, P. and Debatin, K.M. (1989) Apoptosis in monoclonal antibody-induced tumor regression. In: Melchers, F., (ed.) Progress in Immunology. Proceedings of the 7th International Congress of Immunology Berlin 1989, VII. Springer, pp. 1104-1105. ISBN 0387510532; 978-0387510538.

Falk, Werner, Männel, D.N., Darjes, H. and Krammer, P.H. (1989) IL-1 induces high affinity IL-2 receptor expression of CD4-8- thymocytes. Journal of immunology (Baltimore, Md. : 1950) 143 (2), pp. 513-517.

Von Hoegen, I., Falk, Werner, Kojouharoff, G. and Krammer, P. H. (1989) Internalization of interleukin 1 (IL 1) correlates with IL 1-induced IL 2 receptor expression and IL 2 secretion of EL4 thymoma cells. European journal of immunology 19 (2), pp. 329-334.

Debatin, K.M., Woodroofe, C., Lahm, H., Fischer, J., Falk, Werner, Brandeis, W.E. and Krammer, P.H. (1989) Lack of interleukin-2 (IL-2) dependent growth of TAC positive T-ALL/NHL cells is due to the expression of only low affinity receptors for IL-2. Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 3 (8), pp. 566-571.

Trauth, B.C., Klas, C., Peters, A.M., Matzku, S., Möller, P., Falk, Werner, Debatin, K.M. and Krammer, P.H. (1989) Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science (New York, N.Y.) 245 (4915), pp. 301-305.

Männel, D.N. and Falk, Werner (1989) Optimal induction of tumor necrosis factor production in human monocytes requires complete S-form lipopolysaccharide. Infection and immunity 57 (7), pp. 1953-1958.

1988

Männel, D.N., Northoff, H., Bauss, F. and Falk, Werner (1988) Tumor necrosis factor: a cytokine involved in toxic effect of endotoxin. In: Urbaschek, B., (ed.) Perspectives on Bacterial pathogenesis and Host Defence. University of Chicago Press, Chicago, pp. 194-198. ISBN 0226842754; 978-0226842752.

1987

Kojouharoff, G., Vonhoegen, I., Männel, Daniela N., Krammer, P.H. and Falk, Werner (1987) CHARACTERIZATION OF T-CELL-CYTOTOXICITY-INDUCING-FACTOR 1 (TCF-1), A T-CELL PRODUCT THAT INDUCES MURINE THYMOCYTE DIFFERENTIATION. Immunobiology 175 (4), pp. 313-314. Fulltext not available.

Falk, Werner, Krammer, P.H. and Männel, D.N. (1987) A new assay for interleukin-1 in the presence of interleukin-2. Journal of immunological methods 99 (1), pp. 47-52.

Li-Weber, M., Eder, A., Albrecht, M.P., Hoegen, I. von, Jäggle, C., Klas, C., Näher, H., Pekar, U., Hederer, R., Peters, A., Trauth, B., Meinzer, H., Scheppelmann, D., Schmidt, M., Wolf, T., Falk, Werner, Petzoldt, D. and Krammer, P.H. (1987) Die Grundlagen der Aktivierung von T-Helferzellen und ihre Beziehung zum Krankheitsbild Aids. In: Aids: Forschungsergebnisse im Rahmen des Statusseminars des BMFT. Projektgruppe Aids des BGA, Berlin, Berlin, pp. 156-169. Fulltext not available.

Männel, D.N., Falk, Werner and Northoff, H. (1987) Endotoxic activities of tumor necrosis factor independent of IL1 secretion by macrophages/monocytes. Lymphokine research 6 (3), pp. 151-159.

Esparza, I., Männel, Daniela N., Ruppel, A., Falk, Werner and Krammer, P.H. (1987) Interferon gamma and lymphotoxin or tumor necrosis factor act synergistically to induce macrophage killing of tumor cells and schistosomula of Schistosoma mansoni. The Journal of experimental medicine 166 (2), pp. 589-594.

Männel, Daniela N., Northoff, H., Bauss, F. and Falk, Werner (1987) Tumor necrosis factor: a cytokine involved in toxic effects of endotoxin. Reviews of infectious diseases 9 Suppl 5, S602-S606. Fulltext not available.

1986

Männel, D.N. and Falk, Werner (1986) Biologische Mechanismen der Endotoxin-induzierten Tumornekrose. In: Hager, E.D. and Abel, U., (eds.) Biomodulation und Biotherapie des Krebses. Vorträge des 1. Kongresses der Gesellschaft für Biologische Krebsabwehr und der Deutschen Gesellschaft für Onkologie. Fischer, Heidelberg, pp. 102-118. ISBN 3-88463-082-2. Fulltext not available.

Männel, Daniela N., Dröge, W. and Falk, Werner (1986) REGULATION OF T-CELL FUNCTION WITH MONOCLONAL ANTI-THY-1 ANTIBODIES. Journal of Cellular Biochemistry (Suppl.), p. 79. Fulltext not available.

1985

Männel, D.N., Dröge, W. and Falk, Werner (1985) A combination of soluble helper factors bypasses the requirement for stimulator cells and induces nonspecific cytotoxic T cell responses. Immunobiology 170 (3), pp. 146-157.

Falk, Werner, Männel, D.N., Katzer, B., Kaltmann, B., Krammer, P.H., Diamantstein, T. and Dröge, W. (1985) Induction of IL 2 receptor expression and cytotoxicity of thymocytes by stimulation with TCF1. Journal of immunology (Baltimore, Md. : 1950) 135 (2), pp. 1160-1164.

Männel, D.N., Falk, Werner and Dröge, W. (1985) Induction of T cell proliferation and cytotoxicity by lymphokines. Lymphokine research 4 (2), pp. 133-138.

Männel, D.N., Mizel, S.B., Diamantstein, T. and Falk, Werner (1985) Induction of interleukin 2 responsiveness in thymocytes by synergistic action of interleukin 1 and interleukin 2. Journal of immunology (Baltimore, Md. : 1950) 134 (5), pp. 3108-3110.

Wolf, M., Falk, Werner, Männel, D.N. and Dröge, W. (1985) Inhibition of interleukin 2 production by prostaglandin E2 is not absolute but depends on the strength of the stimulating signal. Cellular immunology 90 (1), pp. 190-195.

Krammer, P.H., Kubelka, C.F., Falk, Werner and Ruppel, A. (1985) Priming and triggering of tumoricidal and schistosomulicidal macrophages by two sequential lymphokine signals: interferon-gamma and macrophage cytotoxicity inducing factor 2. Journal of immunology (Baltimore, Md. : 1950) 135 (5), pp. 3258-3263.

Dröge, W., Männel, D.N., Falk, Werner, Lehmann, V., Schmidt, H., Nick, S., Häcker-Shahin, B. and Jänicke, R. (1985) Suppression of cytotoxic T lymphocyte activation by L-ornithine. Journal of immunology (Baltimore, Md. : 1950) 134 (5), pp. 3379-3383.

Männel, D.N. and Falk, Werner (1985) T cell cytotoxicity inducing factor 1 (TCF1) is a T cell product that induces thymocyte differentiation. In: Sorg, C. and Schimpl, A., (eds.) Cellular and Molecular Biology of Lymphokines. International Lymphokine Workshop 1984 at Schloss Elmau. Academic Press, New York, pp. 93-98. ISBN 0126561605; 978-0126561609. Fulltext not available.

1984

Dröge, W., Moyers, C., Wehrmaker, A., Schmidt, H., Panknin, S., Männel, D.N. and Falk, Werner (1984) Capacity of different cell types to stimulate cytotoxic T lymphocyte precursor cells in the presence of interleukin 2. Journal of immunology (Baltimore, Md. : 1950) 132 (6), pp. 2749-2759.

Männel, Daniela N., Falk, Werner, Herrmann, T., Osawa, H. and Diamantstein, T. (1984) INDUCTION OF T-CELL DIFFERENTIATION BY A SOLUBLE MEDIATOR. Immunobiology 168 (1-2), p. 7. Fulltext not available.

1983

Falk, Werner, Männel, D.N. and Dröge, W. (1983) Activation of cytotoxic T lymphocytes requires at least two spleen cell-derived helper factors besides interleukin 2. Journal of immunology (Baltimore, Md. : 1950) 130 (5), pp. 2214-2218.

Krammer, P.H., Dy, M., Falk, Werner, Gemsa, D., Hültner, L., Isakson, P., Kees, U., Kirchner, H., Lohmann Matthes, M.L., Marcucci, F., Puré, E., Schimpl, A., Staber, F. and Vitetta, E.S. (1983) Aspects of alloreactivity: Lymphokine release from alloreactive T cell clones in long term culture. In: Vitetta, E.S., (ed.) B and T Cell Tumors. UCLA Symposium on Molecular and Cellular Biology. Academic Press, New York, pp. 109-112. ISBN 0127223800; 978-0127223803. Fulltext not available.

Falk, Werner and Männel, D.N. (1983) Induction of T cell cytotoxicity is regulated by a minimum of three different lymphokines. In: Oppenheim, J.J. and Cohen, S., (eds.) Interleukins, Lymphokines and Cytokines: Proceedings of the Third International Lymphokine Workshop. Academic Press, New York, pp. 109-112. ISBN 0125275404; 978-0125275408. Fulltext not available.

Männel, D.N., Falk, Werner and Dröge, W. (1983) Induction of cytotoxic T cell function requires sequential action of three different lymphokines. The Journal of Immunology 130 (6), pp. 2508-2510.

Männel, Daniela N. and Falk, Werner (1983) Interferon-gamma is required in activation of macrophages for tumor cytotoxicity. Cellular immunology 79 (2), pp. 396-402.

Männel, Daniela N. and Falk, Werner (1983) Requirement of g-interferon in activation of macrophages for tumour cytotoxicity. In: Oppenheim, J. .J. and Cohen, S., (eds.) Interleukins, Lymphokines and Cytokines: Proceedings of the Third International Lymphokine Workshop. Academic Press, New York, pp. 287-290. ISBN 0125275404; 978-0125275408. Fulltext not available.

Dröge, W., Männel, D., Falk, Werner, Schmidt, H., Panknin, S. and Dotterer, W. (1983) The optimal activation of cytotoxic T lymphocytes requires metabolically intact stimulator cells not only for the activation of the interleukin 2-producing helper cells. Journal of immunology (Baltimore, Md. : 1950) 131 (1), pp. 520-528.

1982

Falk, Werner and Leonard, E.J. (1982) Chemotaxis of purified human monocytes in vitro: lack of accessory cell requirement. Infection and immunity 36 (2), pp. 591-597.

Falk, Werner, Harvath, L. and Leonard, E.J. (1982) Functionally distinct subpopulations of human monocytes: receptors for F-Met-Leu-Phe are expressed only on the chemotactically responsive cells. Advances in experimental medicine and biology 155, pp. 101-106. Fulltext not available.

Aksamit, R.R., Falk, Werner and Cantoni, G.L. (1982) Inhibition of chemotaxis by S-3-deazaadenosylhomocysteine in a mouse macrophage cell line. The Journal of biological chemistry 257 (2), pp. 621-625.

Reddehase, M., Suessmuth, W., Moyers, C., Falk, Werner and Droege, W. (1982) Interleukin 2 is not sufficient as helper component for the activation of cytotoxic T lymphocytes but synergizes with a late helper effect that is provided by irradiated I-region-incompatible stimulator cells. Journal of immunology (Baltimore, Md. : 1950) 128 (1), pp. 61-68.

Falk, Werner, Harvath, L. and Leonard, E.J. (1982) Only the chemotactic subpopulation of human blood monocytes expresses receptors for the chemotactic peptide N-formylmethionyl-leucyl-phenylalanine. Infection and immunity 36 (2), pp. 450-454.

Männel, Daniela N. and Falk, Werner (1982) Requirement for γ-interferon in activation of macrophages for tumor cytotoxicity. Cellular Immunology 70 (2), p. 389. Fulltext not available.

1981

Falk, Werner and Leonard, E.J. (1981) A functional subpopulation among normal peripheral blood monocytes. In: Förster, O. and Landy, M., (eds.) Heterogeneity of Mononuclear Phagocytes. Academic Press, London, pp. 156-158. ISBN 0122623606; 978-0122623608. Fulltext not available.

Falk, Werner, Tomisawa, S., Klimetzek, V. and Meltzer, M.S. (1981) Chemotactic activity of bone marrow-derived macrophages changes with time in culture. Infection and immunity 33 (2), pp. 629-631.

Aksamit, R.R., Falk, Werner and Leonard, E.J. (1981) Chemotaxis by mouse macrophage cell lines. Journal of immunology (Baltimore, Md. : 1950) 126 (6), pp. 2194-2199.

Männel, D.N., Falk, Werner and Meltzer, M.S. (1981) Inhibition of nonspecific tumoricidal activity by activated macrophages with antiserum against a soluble cytotoxic factor. Infection and immunity 33 (1), pp. 156-164.

Falk, Werner and Leonard, E.J. (1981) Specificity and reversibility of chemotactic deactivation of human monocytes. Infection and immunity 32 (2), pp. 464-468.

1980

Falk, Werner, Goodwin, R.H. and Leonard, E.J. (1980) A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration. Journal of Immunological Methods 33 (3), pp. 239-247.

Falk, Werner and Leonard, E.J. (1980) Human monocyte chemotaxis: migrating cells are a subpopulation with multiple chemotaxin specificities on each cell. Infection and Immunity 29 (3), pp. 953-959.

Harvath, L., Falk, Werner and Leonard, E.J. (1980) Rapid quantitation of neutrophil chemotaxis: use of a polyvinylpyrrolidone-free polycarbonate membrane in a multiwell assembly. Journal of immunological methods 37 (1), pp. 39-45.

1972

Falk, Werner and Tamm, C. (1972) Nucleoside und Nucleotide. Teil 3: Über die Polykondensation von Thymidin-3'-phosphat nach der Triestermethode. Helvetica Chimica Acta 55 (6), pp. 1928-1947.

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