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, Falk, Werner, Fried, Michael, Rogler, Gerhard und Scharl, Michael
(2016)
NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22.
Journal of Clinical Investigation 126 (5), S. 1783-1800.
Volltext nicht vorhanden.
, Becher, Burkhard, Falk, Werner, Fried, Michael, Rogler, Gerhard und Scharl, Michael
(2016)
NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22.
Journal of Clinical Investigation 126 (11), S. 4388.
Volltext nicht vorhanden.
Lippert, Elisabeth, Stieber-Gunckel, Manuela, Dunger, Nadja, Falk, Werner, Obermeier, Florian und Kunst, Claudia
(2015)
Galectin-3 Modulates Experimental Colitis.
Digestion 92 (1), S. 45-53.
(2014)
Exogenous Heat Shock Protein gp96 Ameliorates CD4+CD62L+ T-Cell–mediated Transfer Colitis.
Inflammatory Bowel Diseases 20 (11), S. 1933-1941.
Volltext nicht vorhanden.
, Falk, Werner und Obermeier, Florian
(2014)
Physiologic TLR9-CpG-DNA Interaction Is Essential for the Homeostasis of the Intestinal Immune System.
Inflammatory Bowel Diseases 20 (1), S. 136-143.
Volltext nicht vorhanden.
, Falk, Werner und Radons, Jürgen
(2012)
(−)-Epigallocatechin-3-gallate, a green tea-derived catechin, synergizes with celecoxib to inhibit IL-1-induced tumorigenic mediators by human pancreatic adenocarcinoma cells Colo357.
European Journal of Pharmacology 684 (1-3), S. 36-43.
Volltext nicht vorhanden.
Hetzenegger, A. M., Seidl, M. C., Kosovac, K., Herfarth, H., Kellermeier, S., Obermeier, Florian, Falk, Werner, Schölmerich, Jürgen, Rogler, Gerhard und make_name_string expected hash reference
(2012)
Downregulation of the Ubiquitin-Proteasome System in Normal Colonic Macrophages and Reinduction in Inflammatory Bowel Disease.
Digestion 86, S. 34-47.
, Tomisato, Wataru, Li, Xiaohong, Neppl, Christina, Pirie, Elaine, Falk, Werner, Xia, Yu, Moresco, Eva Marie Y., Baccala, Roberto, Theofilopoulos, Argyrios N., Schnabl, Bernd und Beutler, Bruce
(2012)
Yip1 domain family, member 6 (Yipf6) mutation induces spontaneous intestinal inflammation in mice.
Proceedings of the National Academy of Sciences 109 (31), S. 12650-12655.
Volltext nicht vorhanden.
, Kiessling, Stephan, Villunger, Andreas, Becker, Helen, Hofmann, Claudia, Falk, Werner, Krebs, Michaela, Kellermeier, Silvia, Fried, Michael, Schölmerich, Jürgen, Obermeier, Florian und Rogler, Gerhard
(2011)
BCL-2 Modifying Factor (BMF) Is a Central Regulator of Anoikis in Human Intestinal Epithelial Cells.
Journal of Biological Chemistry 286 (30), S. 26533-26540.
Volltext nicht vorhanden.
, Falk, Werner und Radons, Jürgen
(2011)
EGCG downregulates IL-1RI expression and suppresses IL-1-induced tumorigenic factors in human pancreatic adenocarcinoma cells.
Biochemical Pharmacology 82 (9), S. 1153-1162.
Volltext nicht vorhanden.
(2010)
Association of the NOD2 genotype with bacterial translocation via altered cell–cell contacts in Crohnʼs disease patients.
Inflammatory Bowel Diseases 16 (8), S. 1311-1321.
Volltext nicht vorhanden.
, Alviano, Francesco, Bergwerf, Irene, Boraschi, Diana, De Bari, Cosimo, De Waele, Peter, Dominici, Massimo
, Evangelista, Marco, Falk, Werner, Hennerbichler, Simone, Hess, David C., Lanzoni, Giacomo
, Liu, Bing, Marongiu, Fabio
, McGuckin, Colin, Mohr, Stefan, Nolli, Maria Luisa, Ofir, Racheli, Ponsaerts, Peter
, Romagnoli, Luca, Solomon, Abraham
, Soncini, Maddalena, Strom, Stephen
, Surbek, Daniel, Venkatachalam, Sankar, Wolbank, Susanne, Zeisberger, Steffen, Zeitlin, Andy, Zisch, Andreas und Borlongan, Cesar V.
(2010)
Toward Cell Therapy Using Placenta-Derived Cells: Disease Mechanisms, Cell Biology, Preclinical Studies, and Regulatory Aspects at the Round Table.
Stem Cells and Development 19 (2), S. 143-154.
Volltext nicht vorhanden.
und Hausmann, Martin
(2009)
Gene expression profiles of mucosal fibroblasts from strictured and nonstrictured areas of patients with Crohnʼs disease.
Inflammatory Bowel Diseases 15 (2), S. 212-223.
Volltext nicht vorhanden.
, Dierkes, Christine, Schölmerich, Jürgen, Salzberger, Bernd, Glück, Thomas und Falk, Werner
(2009)
Lipopolysaccharide-Trap-Fc, a Multifunctional Agent To Battle Gram-Negative Bacteria.
Infection and Immunity 77 (7), S. 2925-2931.
Volltext nicht vorhanden.
und Obermeier, Florian
(2009)
Primary human colonic epithelial cells are transiently protected from anoikis by a Src-dependent mechanism.
Biochemical and Biophysical Research Communications 390 (3), S. 908-914.
Volltext nicht vorhanden.
, Mirsky, Vladimir M.
und Straub, Rainer H.
(2009)
Soluble neuropilin‐2, a nerve repellent receptor, is increased in rheumatoid arthritis synovium and aggravates sympathetic fiber repulsion and arthritis.
Arthritis & Rheumatism 60 (10), S. 2892-2901.
Volltext nicht vorhanden.
(2009)
Transforming growth factor-β1 induces intestinal myofibroblast differentiation and modulates their migration.
World Journal of Gastroenterology 15 (12), S. 1431.
Volltext nicht vorhanden.
, Fink, Marina, Gross, Philipp, Taura, Kojiro, Gäbele, Erwin, Hellerbrand, Claus und Falk, Werner
(2008)
A TLR4/MD2 fusion protein inhibits LPS-induced pro-inflammatory signaling in hepatic stellate cells.
Biochemical and Biophysical Research Communications 375 (2), S. 210-214.
Volltext nicht vorhanden.
(2008)
Inflammation modulates fibronectin isoform expression in colonic lamina propria fibroblasts (CLPF).
International Journal of Colorectal Disease 23 (10), S. 947-955.
Volltext nicht vorhanden.
(2007)
10 Relevance of IL-18 in DSS-induced Colitis in Mice.
Cytokine 39 (1), S. 3.
Volltext nicht vorhanden.
, Bull, Arthur W., Menzel, Katrin, Vogl, Daniela, Herfarth, Hans, Schölmerich, Jürgen, Falk, Werner und Rogler, Gerhard
(2007)
13-Oxo-ODE is an endogenous ligand for PPARγ in human colonic epithelial cells.
Biochemical Pharmacology 74 (4), S. 612-622.
Volltext nicht vorhanden.
und Grossmann, Johannes
(2007)
Cell-Cell Contacts Prevent Anoikis in Primary Human Colonic Epithelial Cells.
Gastroenterology 132 (2), S. 587-600.
Volltext nicht vorhanden.
(2007)
Evidence for a differential expression of fibronectin splice forms ED-A and ED-B in Crohn’s disease (CD) mucosa.
International Journal of Colorectal Disease 22 (6), S. 611-623.
Volltext nicht vorhanden.
(2006)
IL‐15 protects intestinal epithelial cells.
European Journal of Immunology 36 (10), S. 2691-2699.
Volltext nicht vorhanden.
, Weidler, Claudia, Linde, Hans‐Jörg, Kirschning, Carsten J., Glück, Thomas, Schölmerich, Jürgen und Falk, Werner
(2005)
Ablation of the Sympathetic Nervous System Decreases Gram‐Negative and Increases Gram‐Positive Bacterial Dissemination: Key Roles for Tumor Necrosis Factor/Phagocytes and Interleukin‐4/Lymphocytes.
The Journal of Infectious Diseases 192 (4), S. 560-572.
Volltext nicht vorhanden.
, Schölmerich, Jürgen und Falk, Werner
(2005)
CpG Motifs of Bacterial DNA Essentially Contribute to the Perpetuation of Chronic Intestinal Inflammation.
Gastroenterology 129 (3), S. 913-927.
Volltext nicht vorhanden.
(2004)
Increased prevalence of semaphorin 3C, a repellent of sympathetic nerve fibers, in the synovial tissue of patients with rheumatoid arthritis.
Arthritis & Rheumatism 50 (4), S. 1156-1163.
Volltext nicht vorhanden.
(2004)
Neutralization of CD95 ligand promotes regeneration and functional recovery after spinal cord injury.
Nature Medicine 10 (4), S. 389-395.
Volltext nicht vorhanden.
, Altmann, Reinhold, Botzki, Alexander
, Martin, Michael U. und Falk, Werner
(2003)
The Interleukin 1 (IL-1) Receptor Accessory Protein Toll/IL-1 Receptor Domain.
Journal of Biological Chemistry 278 (49), S. 49145-49153.
Volltext nicht vorhanden.
, Jessop, David S., Falk, Werner und Schölmerich, Jürgen
(2000)
Neuropeptide Y Cotransmission with Norepinephrine in the Sympathetic Nerve—Macrophage Interplay.
Journal of Neurochemistry 75 (6), S. 2464-2471.
Volltext nicht vorhanden.
Falk, Werner, Stricker, K., Praast, G., Tsukitani, Y., Krammer, P. H. und Stoeck, M.
(1994)
Activation of the mouse IL-2 gene by okadaic acid: synergy with interleukin-1.
Lymphokine and cytokine research 13 (3), S. 167-174.
Männel, D. N., Orosz, P., Hafner, M. und Falk, Werner
(1994)
Mechanisms involved in metastasis enhanced by inflammatory mediators.
Circulatory shock 44 (1), S. 9-13.
Stricker, K., Serfling, E., Krammer, P. H. und Falk, Werner
(1993)
An NF-kappa B-like element plays an essential role in interleukin-1-mediated costimulation of the mouse interleukin-2 promoter.
European journal of immunology 23 (7), S. 1475-1480.
Orosz, P., Echtenacher, Bernd, Falk, Werner, Rüschoff, J., Weber, D. und Männel, Daniela N.
(1993)
Enhancement of experimental metastasis by tumor necrosis factor.
The Journal of experimental medicine 177 (5), S. 1391-1398.
Echtenacher, B., Falk, Werner, Männel, D. N. und Krammer, P. H.
(1993)
Survival from cecal ligation and puncture and the formation of fibrous adhesions in the peritoneal cavity depend on endogenous tumor necrosis factor.
In: Faist, E. und Meakins, J. L., (eds.)
Host Defense Dysfunction in Trauma, Shock and Sepsis.
Springer, Berlin u.a., S. 755-758.
Männel, D. N., Orosz, P., Echtenacher, B., Rüschoff, J. und Falk, Werner
(1993)
Zytokine in der Tumor-Wirt-Interaktion.
In: Wilmanns, W., (ed.)
Zytokine.
Thieme, Stuttgart, S. 116-119.
Oehm, A., Behrmann, I., Falk, Werner, Pawlita, M., Maier, G., Klas, C., Li-Weber, M., Richards, S., Dhein, J. und Trauth, B. C.
(1992)
Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen.
The Journal of biological chemistry 267 (15), S. 10709-10715.
Männel, D. N., Jänicke, R., Westenfelder, U., Orosz, P. G., Echtenacher, B., Kist, A. und Falk, Werner
(1992)
Tumor cell-induced TNF production.
In: Osawa, T. und Bonavida, B., (eds.)
Tumor Necrosis Factor: Structure Function Relationship and Clinical Application.
Karger, Basel, S. 166-172.
Krammer, P. H., Behrmann, I., Bier, V., Daniel, P., Dhein, J., Falk, M. H., Garcin, G., Klas, C., Knipping, E., Lücking-Famira, K. M., Matzku, S., Oehm, A., Richards, S., Trauth, B. C., Bornkamm, G. W., Falk, Werner, Möller, P. und Debatin, K. M.
(1991)
Apoptosis in the Apo-1 system.
In: Tomei, J. und Cope, F., (eds.)
Apoptosis: The Molecular Basis of Cell Death.
Harbour Laboratory Press, Cold Spring, S. 87-99.
Zawatzky, R., Wurmbaeck, H., Falk, Werner und Homfeld, A.
(1991)
Endogenous interferon specifically regulates Newcastle disease virus-induced cytokine gene expression in mouse macrophages.
Journal of virology 65 (9), S. 4839-4846.
Männel, D. N., Falk, Werner und Yron, I.
(1990)
Inhibition of murine cytotoxic T cell responses by progesterone.
Immunology letters 26 (1), S. 89-94.
Falk, Werner, Albrecht, M. P., Stricker, K., Serfling, E. und Krammer, P. H.
(1990)
Internalization of IL-1 is required for IL-2 gene activation in EL4 thymoma cells.
In: Oppenheim, J. J. und Powanda, M. C. und Kluger, M. J. und Cinarello, C. A., (eds.)
Progress in Leukocyte Biology 10A: Molecular and Cellular biology of Cytokines.
Wiley-Liss, New York u.a., S. 191-196.
Echtenacher, B., Falk, Werner, Männel, D. N. und Krammer, P. H.
(1990)
Requirement of endogenous tumor necrosis factor/cachectin for recovery from experimental peritonitis.
Journal of immunology (Baltimore, Md. : 1950) 145 (11), S. 3762-3766.
Männel, D. N., Jänicke, R., Westenfelder, U., Echtenacher, B., Kist, A. und Falk, Werner
(1990)
Tumor-induced tumor necrosis factor production in macrophages.
Lymphokine research 9 (4), S. 485-489.
Falk, Werner, von Hoegen, I. und Krammer, P. H.
(1989)
Activation of T cells by interleukin 1 involves internalization of interleukin 1.
Lymphokine research 8 (3), S. 263-268.
Krammer, P. H., Trauth, B. C., Bier, V., Dhein, J., Falk, Werner, Garcin, G., Klas, C., Müller, W., Oehm, A., Peters, A. M. J., Matzku, S., Möller, P. und Debatin, K. M.
(1989)
Apoptosis in monoclonal antibody-induced tumor regression.
In: Melchers, F., (ed.)
Progress in Immunology.
Proceedings of the 7th International Congress of Immunology Berlin 1989, VII.
Springer, S. 1104-1105.
ISBN 0387510532; 978-0387510538.
Falk, Werner, Männel, D. N., Darjes, H. und Krammer, P. H.
(1989)
IL-1 induces high affinity IL-2 receptor expression of CD4-8- thymocytes.
Journal of immunology (Baltimore, Md. : 1950) 143 (2), S. 513-517.
von Hoegen, I., Falk, Werner, Kojouharoff, G. und Krammer, P. H.
(1989)
Internalization of interleukin 1 (IL 1) correlates with IL 1-induced IL 2 receptor expression and IL 2 secretion of EL4 thymoma cells.
European journal of immunology 19 (2), S. 329-334.
Debatin, K. M., Woodroofe, C., Lahm, H., Fischer, J., Falk, Werner, Brandeis, W. E. und Krammer, P. H.
(1989)
Lack of interleukin-2 (IL-2) dependent growth of TAC positive T-ALL/NHL cells is due to the expression of only low affinity receptors for IL-2.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 3 (8), S. 566-571.
Trauth, B. C., Klas, C., Peters, A. M., Matzku, S., Möller, P., Falk, Werner, Debatin, K. M. und Krammer, P. H.
(1989)
Monoclonal antibody-mediated tumor regression by induction of apoptosis.
Science (New York, N.Y.) 245 (4915), S. 301-305.
Männel, D. N. und Falk, Werner
(1989)
Optimal induction of tumor necrosis factor production in human monocytes requires complete S-form lipopolysaccharide.
Infection and immunity 57 (7), S. 1953-1958.
Männel, D. N., Northoff, H., Bauss, F. und Falk, Werner
(1988)
Tumor necrosis factor: a cytokine involved in toxic effect of endotoxin.
In: Urbaschek, B., (ed.)
Perspectives on Bacterial pathogenesis and Host Defence.
University of Chicago Press, Chicago, S. 194-198.
ISBN 0226842754; 978-0226842752.
Falk, Werner, Krammer, P. H. und Männel, D. N.
(1987)
A new assay for interleukin-1 in the presence of interleukin-2.
Journal of immunological methods 99 (1), S. 47-52.
Männel, D. N., Falk, Werner und Northoff, H.
(1987)
Endotoxic activities of tumor necrosis factor independent of IL1 secretion by macrophages/monocytes.
Lymphokine research 6 (3), S. 151-159.
Esparza, I., Männel, Daniela N., Ruppel, A., Falk, Werner und Krammer, P. H.
(1987)
Interferon gamma and lymphotoxin or tumor necrosis factor act synergistically to induce macrophage killing of tumor cells and schistosomula of Schistosoma mansoni.
The Journal of experimental medicine 166 (2), S. 589-594.
Männel, D. N., Dröge, W. und Falk, Werner
(1985)
A combination of soluble helper factors bypasses the requirement for stimulator cells and induces nonspecific cytotoxic T cell responses.
Immunobiology 170 (3), S. 146-157.
Falk, Werner, Männel, D. N., Katzer, B., Kaltmann, B., Krammer, P. H., Diamantstein, T. und Dröge, W.
(1985)
Induction of IL 2 receptor expression and cytotoxicity of thymocytes by stimulation with TCF1.
Journal of immunology (Baltimore, Md. : 1950) 135 (2), S. 1160-1164.
Männel, D. N., Falk, Werner und Dröge, W.
(1985)
Induction of T cell proliferation and cytotoxicity by lymphokines.
Lymphokine research 4 (2), S. 133-138.
Männel, D. N., Mizel, S. B., Diamantstein, T. und Falk, Werner
(1985)
Induction of interleukin 2 responsiveness in thymocytes by synergistic action of interleukin 1 and interleukin 2.
Journal of immunology (Baltimore, Md. : 1950) 134 (5), S. 3108-3110.
Wolf, M., Falk, Werner, Männel, D. N. und Dröge, W.
(1985)
Inhibition of interleukin 2 production by prostaglandin E2 is not absolute but depends on the strength of the stimulating signal.
Cellular immunology 90 (1), S. 190-195.
Krammer, P. H., Kubelka, C. F., Falk, Werner und Ruppel, A.
(1985)
Priming and triggering of tumoricidal and schistosomulicidal macrophages by two sequential lymphokine signals: interferon-gamma and macrophage cytotoxicity inducing factor 2.
Journal of immunology (Baltimore, Md. : 1950) 135 (5), S. 3258-3263.
Dröge, W., Männel, D. N., Falk, Werner, Lehmann, V., Schmidt, H., Nick, S., Häcker-Shahin, B. und Jänicke, R.
(1985)
Suppression of cytotoxic T lymphocyte activation by L-ornithine.
Journal of immunology (Baltimore, Md. : 1950) 134 (5), S. 3379-3383.
Dröge, W., Moyers, C., Wehrmaker, A., Schmidt, H., Panknin, S., Männel, D. N. und Falk, Werner
(1984)
Capacity of different cell types to stimulate cytotoxic T lymphocyte precursor cells in the presence of interleukin 2.
Journal of immunology (Baltimore, Md. : 1950) 132 (6), S. 2749-2759.
Falk, Werner, Männel, D. N. und Dröge, W.
(1983)
Activation of cytotoxic T lymphocytes requires at least two spleen cell-derived helper factors besides interleukin 2.
Journal of immunology (Baltimore, Md. : 1950) 130 (5), S. 2214-2218.
Männel, D. N., Falk, Werner und Dröge, W.
(1983)
Induction of cytotoxic T cell function requires sequential action of three different lymphokines.
The Journal of Immunology 130 (6), S. 2508-2510.
Männel, Daniela N. und Falk, Werner
(1983)
Interferon-gamma is required in activation of macrophages for tumor cytotoxicity.
Cellular immunology 79 (2), S. 396-402.
Dröge, W., Männel, D., Falk, Werner, Schmidt, H., Panknin, S. und Dotterer, W.
(1983)
The optimal activation of cytotoxic T lymphocytes requires metabolically intact stimulator cells not only for the activation of the interleukin 2-producing helper cells.
Journal of immunology (Baltimore, Md. : 1950) 131 (1), S. 520-528.
Falk, Werner und Leonard, E.J.
(1982)
Chemotaxis of purified human monocytes in vitro: lack of accessory cell requirement.
Infection and immunity 36 (2), S. 591-597.
Aksamit, R. R., Falk, Werner und Cantoni, G. L.
(1982)
Inhibition of chemotaxis by S-3-deazaadenosylhomocysteine in a mouse macrophage cell line.
The Journal of biological chemistry 257 (2), S. 621-625.
Reddehase, M., Suessmuth, W., Moyers, C., Falk, Werner und Droege, W.
(1982)
Interleukin 2 is not sufficient as helper component for the activation of cytotoxic T lymphocytes but synergizes with a late helper effect that is provided by irradiated I-region-incompatible stimulator cells.
Journal of immunology (Baltimore, Md. : 1950) 128 (1), S. 61-68.
Falk, Werner, Harvath, L. und Leonard, E.J.
(1982)
Only the chemotactic subpopulation of human blood monocytes expresses receptors for the chemotactic peptide N-formylmethionyl-leucyl-phenylalanine.
Infection and immunity 36 (2), S. 450-454.
Falk, Werner, Tomisawa, S., Klimetzek, V. und Meltzer, M. S.
(1981)
Chemotactic activity of bone marrow-derived macrophages changes with time in culture.
Infection and immunity 33 (2), S. 629-631.
Aksamit, R. R., Falk, Werner und Leonard, E. J.
(1981)
Chemotaxis by mouse macrophage cell lines.
Journal of immunology (Baltimore, Md. : 1950) 126 (6), S. 2194-2199.
Männel, D. N., Falk, Werner und Meltzer, M. S.
(1981)
Inhibition of nonspecific tumoricidal activity by activated macrophages with antiserum against a soluble cytotoxic factor.
Infection and immunity 33 (1), S. 156-164.
Falk, Werner und Leonard, E.J.
(1981)
Specificity and reversibility of chemotactic deactivation of human monocytes.
Infection and immunity 32 (2), S. 464-468.
Falk, Werner, Goodwin, R. H. und Leonard, E. J.
(1980)
A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration.
Journal of Immunological Methods 33 (3), S. 239-247.
Falk, Werner und Leonard, E.J.
(1980)
Human monocyte chemotaxis: migrating cells are a subpopulation with multiple chemotaxin specificities on each cell.
Infection and Immunity 29 (3), S. 953-959.
Harvath, L., Falk, Werner und Leonard, E.J.
(1980)
Rapid quantitation of neutrophil chemotaxis: use of a polyvinylpyrrolidone-free polycarbonate membrane in a multiwell assembly.
Journal of immunological methods 37 (1), S. 39-45.
Falk, Werner und Tamm, C.
(1972)
Nucleoside und Nucleotide. Teil 3: Über die Polykondensation von Thymidin-3'-phosphat nach der Triestermethode.
Helvetica Chimica Acta 55 (6), S. 1928-1947.
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