Einträge von Falk, Werner auf dem Publikationsserver

Hoffmann, Maximilian, Schwertassek, Ulla, Seydel, Aleksandra, Weber, Klaus, Falk, Werner, Hauschildt, Sunna und Lehmann, Jörg (2018) A refined and translationally relevant model of chronic DSS colitis in BALB/c mice. Laboratory Animals 52 (3), S. 240-252. Volltext nicht vorhanden.

Spalinger, Marianne R., Kasper, Stephanie, Gottier, Claudia, Lang, Silvia, Atrott, Kirstin, Vavricka, Stephan R., Scharl, Sylvie, Gutte, Petrus M., Grütter, Markus G., Beer, Hans-Dietmar, Contassot, Emmanuel, Chan, Andrew C., Dai, Xuezhi, Rawlings, David J., Mair, Florian, Becher, Burkhard , Falk, Werner, Fried, Michael, Rogler, Gerhard und Scharl, Michael (2016) NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22. Journal of Clinical Investigation 126 (5), S. 1783-1800. Volltext nicht vorhanden.

Spalinger, Marianne R., Kasper, Stephanie, Gottier, Claudia, Lang, Silvia, Atrott, Kirstin, Vavricka, Stephan R., Scharl, Sylvie, Raselli, Tina, Frey-Wagner, Isabelle, Gutte, Petrus M., Grütter, Markus G., Beer, Hans-Dietmar, Contassot, Emmanuel, Chan, Andrew C., Dai, Xuezhi, Rawlings, David J., Mair, Florian , Becher, Burkhard, Falk, Werner, Fried, Michael, Rogler, Gerhard und Scharl, Michael (2016) NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22. Journal of Clinical Investigation 126 (11), S. 4388. Volltext nicht vorhanden.

Lippert, Elisabeth, Stieber-Gunckel, Manuela, Dunger, Nadja, Falk, Werner, Obermeier, Florian und Kunst, Claudia (2015) Galectin-3 Modulates Experimental Colitis. Digestion 92 (1), S. 45-53.

Radons, Jürgen, Falk, Werner und Dove, Stefan (2015) Identification of critical regions within the TIR domain of IL-1 receptor type I. The international journal of biochemistry & cell biology 68, S. 15-20. Volltext nicht vorhanden.

Hetzenegger, A. M., Seidl, M. C., Kosovac, K., Herfarth, H., Kellermeier, S., Obermeier, Florian, Falk, Werner, Schölmerich, Jürgen und Rogler, Gerhard (2012) Downregulation of the Ubiquitin-Proteasome System in Normal Colonic Macrophages and Reinduction in Inflammatory Bowel Disease. Digestion 86, S. 34-47.

Radons, Jürgen, Bosserhoff, Anja Katrin, Grässel, Susanne, Falk, Werner und Schubert, Thomas E. O. (2006) p38MAPK mediates IL-1-induced down-regulation of aggrecan gene expression in human chondrocytes. International journal of molecular medicine 17 (4), S. 661-668. Zugang zum Volltext eingeschränkt.

Radons, Jürgen, Falk, Werner und Schubert, Thomas E. O. (2006) Interleukin-10 does not affect IL-1-induced interleukin-6 and metalloproteinase production in human chondrosarcoma cells, SW1353. International journal of molecular medicine 17 (2), S. 377-383. Zugang zum Volltext eingeschränkt.

Radons, Jürgen, Dove, Stefan, Neumann, D., Altmann, R., Botzki, Alexander, Martin, M. U. und Falk, Werner (2003) The IL-1 receptor accessory protein TIR domain: analysis of putative interaction sites by in-vitro mutagenesis and molecular modeling. The Journal of Biological Chemistry 278 (49), S. 49145-49153. Volltext nicht vorhanden.

Falk, Werner, Stricker, K., Praast, G., Tsukitani, Y., Krammer, P. H. und Stoeck, M. (1994) Activation of the mouse IL-2 gene by okadaic acid: synergy with interleukin-1. Lymphokine and cytokine research 13 (3), S. 167-174.

Männel, D. N., Orosz, P., Hafner, M. und Falk, Werner (1994) Mechanisms involved in metastasis enhanced by inflammatory mediators. Circulatory shock 44 (1), S. 9-13.

Stricker, K., Serfling, E., Krammer, P. H. und Falk, Werner (1993) An NF-kappa B-like element plays an essential role in interleukin-1-mediated costimulation of the mouse interleukin-2 promoter. European journal of immunology 23 (7), S. 1475-1480.

Orosz, P., Echtenacher, Bernd, Falk, Werner, Rüschoff, J., Weber, D. und Männel, Daniela N. (1993) Enhancement of experimental metastasis by tumor necrosis factor. The Journal of experimental medicine 177 (5), S. 1391-1398.

Echtenacher, B., Falk, Werner, Männel, D. N. und Krammer, P. H. (1993) Survival from cecal ligation and puncture and the formation of fibrous adhesions in the peritoneal cavity depend on endogenous tumor necrosis factor. In: Faist, E. und Meakins, J. L., (eds.) Host Defense Dysfunction in Trauma, Shock and Sepsis. Springer, Berlin u.a., S. 755-758.

Männel, D. N., Orosz, P., Echtenacher, B., Rüschoff, J. und Falk, Werner (1993) Zytokine in der Tumor-Wirt-Interaktion. In: Wilmanns, W., (ed.) Zytokine. Thieme, Stuttgart, S. 116-119.

Oehm, A., Behrmann, I., Falk, Werner, Pawlita, M., Maier, G., Klas, C., Li-Weber, M., Richards, S., Dhein, J. und Trauth, B. C. (1992) Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen. The Journal of biological chemistry 267 (15), S. 10709-10715.

Echtenacher, B., Falk, Werner, Männel, D. N. und Krammer, P. H. (1992) TNF in peritonitis of the mouse. In: Ullmann, U. und Dalhoff, A., (eds.) Significance of cytokines in the treatment of infectious deseases. Gustav Fischer, Stuttgart u.a.. Volltext nicht vorhanden.

Männel, D. N., Jänicke, R., Westenfelder, U., Orosz, P. G., Echtenacher, B., Kist, A. und Falk, Werner (1992) Tumor cell-induced TNF production. In: Osawa, T. und Bonavida, B., (eds.) Tumor Necrosis Factor: Structure Function Relationship and Clinical Application. Karger, Basel, S. 166-172.

Krammer, P. H., Behrmann, I., Bier, V., Daniel, P., Dhein, J., Falk, M. H., Garcin, G., Klas, C., Knipping, E., Lücking-Famira, K. M., Matzku, S., Oehm, A., Richards, S., Trauth, B. C., Bornkamm, G. W., Falk, Werner, Möller, P. und Debatin, K. M. (1991) Apoptosis in the Apo-1 system. In: Tomei, J. und Cope, F., (eds.) Apoptosis: The Molecular Basis of Cell Death. Harbour Laboratory Press, Cold Spring, S. 87-99.

Zawatzky, R., Wurmbaeck, H., Falk, Werner und Homfeld, A. (1991) Endogenous interferon specifically regulates Newcastle disease virus-induced cytokine gene expression in mouse macrophages. Journal of virology 65 (9), S. 4839-4846.

Lahm, H., Fischer, J. R., Reichert, Y., Hederer, R., Falk, Werner, Debatin, K. M. und Krammer, P. H. (1990) Autocrine growth factors secreted by the malignant human B-cell-line BJAB are distinct from other known cytokines. European cytokine network 1 (1), S. 41-46. Volltext nicht vorhanden.

Männel, D. N., Falk, Werner und Yron, I. (1990) Inhibition of murine cytotoxic T cell responses by progesterone. Immunology letters 26 (1), S. 89-94.

Falk, Werner, Albrecht, M. P., Stricker, K., Serfling, E. und Krammer, P. H. (1990) Internalization of IL-1 is required for IL-2 gene activation in EL4 thymoma cells. In: Oppenheim, J. J. und Powanda, M. C. und Kluger, M. J. und Cinarello, C. A., (eds.) Progress in Leukocyte Biology 10A: Molecular and Cellular biology of Cytokines. Wiley-Liss, New York u.a., S. 191-196.

Echtenacher, B., Falk, Werner, Männel, D. N. und Krammer, P. H. (1990) Requirement of endogenous tumor necrosis factor/cachectin for recovery from experimental peritonitis. Journal of immunology (Baltimore, Md. : 1950) 145 (11), S. 3762-3766.

Männel, D. N., Jänicke, R., Westenfelder, U., Echtenacher, B., Kist, A. und Falk, Werner (1990) Tumor-induced tumor necrosis factor production in macrophages. Lymphokine research 9 (4), S. 485-489.

Falk, Werner, von Hoegen, I. und Krammer, P. H. (1989) Activation of T cells by interleukin 1 involves internalization of interleukin 1. Lymphokine research 8 (3), S. 263-268.

Krammer, P. H., Trauth, B. C., Bier, V., Dhein, J., Falk, Werner, Garcin, G., Klas, C., Müller, W., Oehm, A., Peters, A. M. J., Matzku, S., Möller, P. und Debatin, K. M. (1989) Apoptosis in monoclonal antibody-induced tumor regression. In: Melchers, F., (ed.) Progress in Immunology. Proceedings of the 7th International Congress of Immunology Berlin 1989, VII. Springer, S. 1104-1105. ISBN 0387510532; 978-0387510538.

Falk, Werner, Männel, D. N., Darjes, H. und Krammer, P. H. (1989) IL-1 induces high affinity IL-2 receptor expression of CD4-8- thymocytes. Journal of immunology (Baltimore, Md. : 1950) 143 (2), S. 513-517.

von Hoegen, I., Falk, Werner, Kojouharoff, G. und Krammer, P. H. (1989) Internalization of interleukin 1 (IL 1) correlates with IL 1-induced IL 2 receptor expression and IL 2 secretion of EL4 thymoma cells. European journal of immunology 19 (2), S. 329-334.

Debatin, K. M., Woodroofe, C., Lahm, H., Fischer, J., Falk, Werner, Brandeis, W. E. und Krammer, P. H. (1989) Lack of interleukin-2 (IL-2) dependent growth of TAC positive T-ALL/NHL cells is due to the expression of only low affinity receptors for IL-2. Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 3 (8), S. 566-571.

Trauth, B. C., Klas, C., Peters, A. M., Matzku, S., Möller, P., Falk, Werner, Debatin, K. M. und Krammer, P. H. (1989) Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science (New York, N.Y.) 245 (4915), S. 301-305.

Männel, D. N. und Falk, Werner (1989) Optimal induction of tumor necrosis factor production in human monocytes requires complete S-form lipopolysaccharide. Infection and immunity 57 (7), S. 1953-1958.

Männel, D. N., Northoff, H., Bauss, F. und Falk, Werner (1988) Tumor necrosis factor: a cytokine involved in toxic effect of endotoxin. In: Urbaschek, B., (ed.) Perspectives on Bacterial pathogenesis and Host Defence. University of Chicago Press, Chicago, S. 194-198. ISBN 0226842754; 978-0226842752.

Kojouharoff, G., von Hoegen, I., Männel, Daniela N., Krammer, P. H. und Falk, Werner (1987) CHARACTERIZATION OF T-CELL-CYTOTOXICITY-INDUCING-FACTOR 1 (TCF-1), A T-CELL PRODUCT THAT INDUCES MURINE THYMOCYTE DIFFERENTIATION. Immunobiology 175 (4), S. 313-314. Volltext nicht vorhanden.

Falk, Werner, Krammer, P. H. und Männel, D. N. (1987) A new assay for interleukin-1 in the presence of interleukin-2. Journal of immunological methods 99 (1), S. 47-52.

Li-Weber, M., Eder, A., Albrecht, M. P., von Hoegen, I., Jäggle, C., Klas, C., Näher, H., Pekar, U., Hederer, R., Peters, A., Trauth, B., Meinzer, H., Scheppelmann, D., Schmidt, M., Wolf, T., Falk, Werner, Petzoldt, D. und Krammer, P. H. (1987) Die Grundlagen der Aktivierung von T-Helferzellen und ihre Beziehung zum Krankheitsbild Aids. In: Aids: Forschungsergebnisse im Rahmen des Statusseminars des BMFT. Projektgruppe Aids des BGA, Berlin, Berlin, S. 156-169. Volltext nicht vorhanden.

Männel, D. N., Falk, Werner und Northoff, H. (1987) Endotoxic activities of tumor necrosis factor independent of IL1 secretion by macrophages/monocytes. Lymphokine research 6 (3), S. 151-159.

Esparza, I., Männel, Daniela N., Ruppel, A., Falk, Werner und Krammer, P. H. (1987) Interferon gamma and lymphotoxin or tumor necrosis factor act synergistically to induce macrophage killing of tumor cells and schistosomula of Schistosoma mansoni. The Journal of experimental medicine 166 (2), S. 589-594.

Männel, Daniela N., Northoff, H., Bauss, F. und Falk, Werner (1987) Tumor necrosis factor: a cytokine involved in toxic effects of endotoxin. Reviews of infectious diseases 9 Suppl 5, S602-S606. Volltext nicht vorhanden.

Männel, D. N. und Falk, Werner (1986) Biologische Mechanismen der Endotoxin-induzierten Tumornekrose. In: Hager, E. D. und Abel, U., (eds.) Biomodulation und Biotherapie des Krebses. Vorträge des 1. Kongresses der Gesellschaft für Biologische Krebsabwehr und der Deutschen Gesellschaft für Onkologie. Fischer, Heidelberg, S. 102-118. ISBN 3-88463-082-2. Volltext nicht vorhanden.

Männel, Daniela N., Dröge, W. und Falk, Werner (1986) REGULATION OF T-CELL FUNCTION WITH MONOCLONAL ANTI-THY-1 ANTIBODIES. Journal of Cellular Biochemistry (Suppl.), S. 79. Volltext nicht vorhanden.

Männel, D. N., Dröge, W. und Falk, Werner (1985) A combination of soluble helper factors bypasses the requirement for stimulator cells and induces nonspecific cytotoxic T cell responses. Immunobiology 170 (3), S. 146-157.

Falk, Werner, Männel, D. N., Katzer, B., Kaltmann, B., Krammer, P. H., Diamantstein, T. und Dröge, W. (1985) Induction of IL 2 receptor expression and cytotoxicity of thymocytes by stimulation with TCF1. Journal of immunology (Baltimore, Md. : 1950) 135 (2), S. 1160-1164.

Männel, D. N., Falk, Werner und Dröge, W. (1985) Induction of T cell proliferation and cytotoxicity by lymphokines. Lymphokine research 4 (2), S. 133-138.

Männel, D. N., Mizel, S. B., Diamantstein, T. und Falk, Werner (1985) Induction of interleukin 2 responsiveness in thymocytes by synergistic action of interleukin 1 and interleukin 2. Journal of immunology (Baltimore, Md. : 1950) 134 (5), S. 3108-3110.

Wolf, M., Falk, Werner, Männel, D. N. und Dröge, W. (1985) Inhibition of interleukin 2 production by prostaglandin E2 is not absolute but depends on the strength of the stimulating signal. Cellular immunology 90 (1), S. 190-195.

Krammer, P. H., Kubelka, C. F., Falk, Werner und Ruppel, A. (1985) Priming and triggering of tumoricidal and schistosomulicidal macrophages by two sequential lymphokine signals: interferon-gamma and macrophage cytotoxicity inducing factor 2. Journal of immunology (Baltimore, Md. : 1950) 135 (5), S. 3258-3263.

Dröge, W., Männel, D. N., Falk, Werner, Lehmann, V., Schmidt, H., Nick, S., Häcker-Shahin, B. und Jänicke, R. (1985) Suppression of cytotoxic T lymphocyte activation by L-ornithine. Journal of immunology (Baltimore, Md. : 1950) 134 (5), S. 3379-3383.

Männel, D. N. und Falk, Werner (1985) T cell cytotoxicity inducing factor 1 (TCF1) is a T cell product that induces thymocyte differentiation. In: Sorg, C. und Schimpl, A., (eds.) Cellular and Molecular Biology of Lymphokines. International Lymphokine Workshop 1984 at Schloss Elmau. Academic Press, New York, S. 93-98. ISBN 0126561605; 978-0126561609. Volltext nicht vorhanden.

Dröge, W., Moyers, C., Wehrmaker, A., Schmidt, H., Panknin, S., Männel, D. N. und Falk, Werner (1984) Capacity of different cell types to stimulate cytotoxic T lymphocyte precursor cells in the presence of interleukin 2. Journal of immunology (Baltimore, Md. : 1950) 132 (6), S. 2749-2759.

Männel, Daniela N., Falk, Werner, Herrmann, T., Osawa, H. und Diamantstein, T. (1984) INDUCTION OF T-CELL DIFFERENTIATION BY A SOLUBLE MEDIATOR. Immunobiology 168 (1-2), S. 7. Volltext nicht vorhanden.

Falk, Werner, Männel, D. N. und Dröge, W. (1983) Activation of cytotoxic T lymphocytes requires at least two spleen cell-derived helper factors besides interleukin 2. Journal of immunology (Baltimore, Md. : 1950) 130 (5), S. 2214-2218.

Krammer, P. H., Dy, M., Falk, Werner, Gemsa, D., Hültner, L., Isakson, P., Kees, U., Kirchner, H., Lohmann Matthes, M. L., Marcucci, F., Puré, E., Schimpl, A., Staber, F. und Vitetta, E. S. (1983) Aspects of alloreactivity: Lymphokine release from alloreactive T cell clones in long term culture. In: Vitetta, E. S., (ed.) B and T Cell Tumors. UCLA Symposium on Molecular and Cellular Biology. Academic Press, New York, S. 109-112. ISBN 0127223800; 978-0127223803. Volltext nicht vorhanden.

Falk, Werner und Männel, D. N. (1983) Induction of T cell cytotoxicity is regulated by a minimum of three different lymphokines. In: Oppenheim, J. J. und Cohen, S., (eds.) Interleukins, Lymphokines and Cytokines: Proceedings of the Third International Lymphokine Workshop. Academic Press, New York, S. 109-112. ISBN 0125275404; 978-0125275408. Volltext nicht vorhanden.

Männel, D. N., Falk, Werner und Dröge, W. (1983) Induction of cytotoxic T cell function requires sequential action of three different lymphokines. The Journal of Immunology 130 (6), S. 2508-2510.

Männel, Daniela N. und Falk, Werner (1983) Interferon-gamma is required in activation of macrophages for tumor cytotoxicity. Cellular immunology 79 (2), S. 396-402.

Männel, Daniela N. und Falk, Werner (1983) Requirement of g-interferon in activation of macrophages for tumour cytotoxicity. In: Oppenheim, J. J. und Cohen, S., (eds.) Interleukins, Lymphokines and Cytokines: Proceedings of the Third International Lymphokine Workshop. Academic Press, New York, S. 287-290. ISBN 0125275404; 978-0125275408. Volltext nicht vorhanden.

Dröge, W., Männel, D., Falk, Werner, Schmidt, H., Panknin, S. und Dotterer, W. (1983) The optimal activation of cytotoxic T lymphocytes requires metabolically intact stimulator cells not only for the activation of the interleukin 2-producing helper cells. Journal of immunology (Baltimore, Md. : 1950) 131 (1), S. 520-528.

Falk, Werner und Leonard, E.J. (1982) Chemotaxis of purified human monocytes in vitro: lack of accessory cell requirement. Infection and immunity 36 (2), S. 591-597.

Falk, Werner, Harvath, L. und Leonard, E.J. (1982) Functionally distinct subpopulations of human monocytes: receptors for F-Met-Leu-Phe are expressed only on the chemotactically responsive cells. Advances in experimental medicine and biology 155, S. 101-106. Volltext nicht vorhanden.

Aksamit, R. R., Falk, Werner und Cantoni, G. L. (1982) Inhibition of chemotaxis by S-3-deazaadenosylhomocysteine in a mouse macrophage cell line. The Journal of biological chemistry 257 (2), S. 621-625.

Reddehase, M., Suessmuth, W., Moyers, C., Falk, Werner und Droege, W. (1982) Interleukin 2 is not sufficient as helper component for the activation of cytotoxic T lymphocytes but synergizes with a late helper effect that is provided by irradiated I-region-incompatible stimulator cells. Journal of immunology (Baltimore, Md. : 1950) 128 (1), S. 61-68.

Falk, Werner, Harvath, L. und Leonard, E.J. (1982) Only the chemotactic subpopulation of human blood monocytes expresses receptors for the chemotactic peptide N-formylmethionyl-leucyl-phenylalanine. Infection and immunity 36 (2), S. 450-454.

Männel, Daniela N. und Falk, Werner (1982) Requirement for γ-interferon in activation of macrophages for tumor cytotoxicity. Cellular Immunology 70 (2), S. 389. Volltext nicht vorhanden.

Falk, Werner und Leonard, E.J. (1981) A functional subpopulation among normal peripheral blood monocytes. In: Förster, O. und Landy, M., (eds.) Heterogeneity of Mononuclear Phagocytes. Academic Press, London, S. 156-158. ISBN 0122623606; 978-0122623608. Volltext nicht vorhanden.

Falk, Werner, Tomisawa, S., Klimetzek, V. und Meltzer, M. S. (1981) Chemotactic activity of bone marrow-derived macrophages changes with time in culture. Infection and immunity 33 (2), S. 629-631.

Aksamit, R. R., Falk, Werner und Leonard, E. J. (1981) Chemotaxis by mouse macrophage cell lines. Journal of immunology (Baltimore, Md. : 1950) 126 (6), S. 2194-2199.

Männel, D. N., Falk, Werner und Meltzer, M. S. (1981) Inhibition of nonspecific tumoricidal activity by activated macrophages with antiserum against a soluble cytotoxic factor. Infection and immunity 33 (1), S. 156-164.

Falk, Werner und Leonard, E.J. (1981) Specificity and reversibility of chemotactic deactivation of human monocytes. Infection and immunity 32 (2), S. 464-468.

Falk, Werner, Goodwin, R. H. und Leonard, E. J. (1980) A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration. Journal of Immunological Methods 33 (3), S. 239-247.

Falk, Werner und Leonard, E.J. (1980) Human monocyte chemotaxis: migrating cells are a subpopulation with multiple chemotaxin specificities on each cell. Infection and Immunity 29 (3), S. 953-959.

Harvath, L., Falk, Werner und Leonard, E.J. (1980) Rapid quantitation of neutrophil chemotaxis: use of a polyvinylpyrrolidone-free polycarbonate membrane in a multiwell assembly. Journal of immunological methods 37 (1), S. 39-45.

Falk, Werner und Tamm, C. (1972) Nucleoside und Nucleotide. Teil 3: Über die Polykondensation von Thymidin-3'-phosphat nach der Triestermethode. Helvetica Chimica Acta 55 (6), S. 1928-1947.