Bibliography of the Universität Regensburg

Wernig-Zorc, Sara , Kugler, Fabian , Schmutterer, Leo , Räß, Patrick , Hausmann, Clemens, Holzinger, Simon , Längst, Gernot and Schwartz, Uwe (2024) nucMACC: An MNase-seq pipeline to identify structurally altered nucleosomes in the genome. Science Advances 10 (27), eadm9740.

Bludau, Anna , Schwartz, Uwe , Zeitler, Daniela M., Royer, Melanie , Meister, Gunter , Neumann, Inga D. and Menon, Rohit (2023) Functional involvement of septal miR-132 in extinction and oxytocin-mediated reversal of social fear. Molecular Psychiatry.

Schwartz, Uwe , Komatsu, Tetsuro, Huber, Claudia, Lagadec, Floriane, Baumgartl, Conradin, Silberhorn, Elisabeth, Nuetzel, Margit, Rayne, Fabienne, Basyuk, Eugenia, Bertrand, Edouard, Rehli, Michael , Wodrich, Harald and Laengst, Gernot (2023) Changes in adenoviral chromatin organization precede early gene activation upon infection. The EMBO Journal.

Markusch, Hanna, Michl‐Holzinger, Philipp, Obermeyer, Simon, Thorbecke, Claudia, Bruckmann, Astrid , Babl, Sabrina, Längst, Gernot , Osakabe, Akihisa, Berger, Frédéric and Grasser, Klaus D. (2023) Elongation factor 1 is a component of the Arabidopsis RNA polymerase II elongation complex and associates with a subset of transcribed genes. New Phytologist 238 (1), pp. 113-124.

Michl-Holzinger, Philipp, Obermeyer, Simon, Markusch, Hanna, Pfab, Alexander, Ettner, Andreas, Bruckmann, Astrid, Babl, Sabrina, Längst, Gernot, Schwartz, Uwe, Tvardovskiy, Andrey, Jensen, Ole N. , Osakabe, Akihisa, Berger, Frédéric and Grasser, Klaus D. (2022) Phosphorylation of the FACT histone chaperone subunit SPT16 affects chromatin at RNA polymerase II transcriptional start sites in Arabidopsis. Nucleic Acids Research 50 (9), pp. 5014-5028.

Peterhoff, David , Thalhauser, Stefanie, Neckermann, Patrick , Barbey, Clara, Straub, Kristina, Nazet, Julian, Merkl, Rainer, Längst, Gernot, Breunig, Miriam and Wagner, Ralf (2022) Multivalent display of engineered HIV-1 envelope trimers on silica nanoparticles for targeting and in vitro activation of germline VRC01 B cells. European Journal of Pharmaceutics and Biopharmaceutics 181, pp. 88-101. Fulltext not available.

Längst, Gernot, Watzlowik, Maria Theresia, Das, Sujaan and Meissner, Markus (2021) Peculiarities of Plasmodium falciparum Gene Regulation and Chromatin Structure. International Journal of Molecular Sciences 2021 (22), p. 5168. (Submitted)

Hoffmeister, Helen, Fuchs, Andreas , Komives, Elizabeth, Groebner‐Ferreira, Regina, Strobl, Laura, Nazet, Julian, Heizinger, Leonhard, Merkl, Rainer, Dove, Stefan and Längst, Gernot (2021) Sequence and functional differences in the ATPase domains of CHD3 and SNF2H promise potential for selective regulability and drugability. The FEBS Journal 288, pp. 4000-4023.

Kargapolova, Yulia , Rehimi, Rizwan, Kayserili, Hülya , Brühl, Joanna, Sofiadis, Konstantinos, Zirkel, Anne, Palikyras, Spiros, Mizi, Athanasia, Li, Yun, Yigit, Gökhan , Hoischen, Alexander , Frank, Stefan, Russ, Nicole, Trautwein, Jonathan, van Bon, Bregje, Gilissen, Christian , Laugsch, Magdalena, Gusmao, Eduardo Gade, Josipovic, Natasa , Altmüller, Janine, Nürnberg, Peter, Längst, Gernot, Kaiser, Frank J., Watrin, Erwan, Brunner, Han, Rada-Iglesias, Alvaro , Kurian, Leo , Wollnik, Bernd , Bouazoune, Karim and Papantonis, Argyris (2021) Overarching control of autophagy and DNA damage response by CHD6 revealed by modeling a rare human pathology. Nature Communications 12 (1). Fulltext not available.

Maiser, Andreas , Dillinger, Stefan, Längst, Gernot, Schermelleh, Lothar , Leonhardt, Heinrich and Németh, Attila (2020) Super-resolution in situ analysis of active ribosomal DNA chromatin organization in the nucleolus. Scientific Reports 10 (7642), pp. 1-11.

Minderjahn, Julia, Schmidt, Andreas, Fuchs, Andreas , Schill, Rudolf, Raithel, Johanna, Babina, Magda , Schmidl, C. , Gebhard, Claudia, Schmidhofer, Sandra, Mendes, Karina , Ratermann, Anna, Glatz, Dagmar, Nützel, Margit, Edinger, Matthias, Hoffmann, Petra, Spang, Rainer , Längst, Gernot, Imhof, A. and Rehli, Michael (2020) Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1. Nat Commun 11, p. 402.

Kulich, Ivan, Vogler, Frank, Bleckmann, Andrea, Cyprys, Philipp, Lindemeier, Maria, Fuchs, Ingrid, Krassini, Laura, Schubert, Thomas, Steinbrenner, Jens , Beynon, Jim, Falter-Braun, Pascal, Längst, Gernot, Dresselhaus, Thomas and Sprunck, Stefanie (2020) ARMADILLO REPEAT ONLY proteins confine Rho GTPase signalling to polar growth sites. Nature Plants 6 (10), pp. 1275-1288. Fulltext not available.

Killian, Tobias, Buntz, Annette, Herlet, Teresa, Seul, Heike, Mundigl, Olaf, Längst, Gernot and Brinkmann, Ulrich (2019) Antibody-targeted chromatin enables effective intracellular delivery and functionality of CRISPR/Cas9 expression plasmids. Nucleic Acids Research 47 (10), e55-e55. Fulltext not available.

Hoffmeister, Helen, Fuchs, Andreas , Strobl, Laura, Sprenger, Frank, Gröbner-Ferreira, Regina, Michaelis, Stefanie, Hoffmann, Petra, Nazet, Julian, Merkl, Rainer and Längst, Gernot (2019) Elucidation of the functional roles of the Q and I motifs in the human chromatin-remodeling enzyme BRG1. Journal of Biological Chemistry 294 (9), pp. 3294-3310. Fulltext not available.

Woloszynska, Magdalena , Le Gall, Sabine, Neyt, Pia , Boccardi, Tommaso M., Grasser, Marion, Längst, Gernot, Aesaert, Stijn, Coussens, Griet, Dhondt, Stijn , Van De Slijke, Eveline, Bruno, Leonardo, Fung-Uceda, Jorge, Mas, Paloma , Van Montagu, Marc, Inzé, Dirk, Himanen, Kristiina , De Jaeger, Geert, Grasser, Klaus D. and Van Lijsebettens, Mieke (2019) Histone 2B monoubiquitination complex integrates transcript elongation with RNA processing at circadian clock and flowering regulators. Proceedings of the National Academy of Sciences 116 (16), pp. 8060-8069. Fulltext not available.

Maldonado, Rodrigo, Schwartz, Uwe, Silberhorn, Elisabeth and Längst, Gernot (2019) Nucleosomes Stabilize ssRNA-dsDNA Triple Helices in Human Cells. Molecular Cell 73 (6), 1243-1254.e6. Fulltext not available.

Ehrnsberger, Hans F., Pfaff, Christina, Hachani, Ines, Flores-Tornero, María , Sørensen, Brian B., Längst, Gernot, Sprunck, Stefanie, Grasser, Marion and Grasser, Klaus D. (2019) The UAP56-Interacting Export Factors UIEF1 and UIEF2 Function in mRNA Export. Plant Physiology 179 (4), pp. 1525-1536. Fulltext not available.

Azuara-Medina, Paulina Margarita, Sandoval-Duarte, Ariana María, Morales-Lázaro, Sara L., Modragón-González, Ricardo, Vélez-Aguilera, Griselda, Gómez-López, Juan de Dios, Jiménez-Gutiérrez, Guadalupe Elizabeth, Tiburcio-Félix, Reynaldo, Martínez-Vieyra, Ivette, Suárez-Sánchez, Rocío, Längst, Gernot, Magaña, Jonathan Javier, Winder, Steve J., Ortega, Arturo , Ramos Perlingeiro, Rita de Cassia, Jacobs, Laura A. and Cisneros, Bulmaro (2019) The intracellular domain of β-dystroglycan mediates the nucleolar stress response by suppressing UBF transcriptional activity. Cell Death & Disease 10 (3). Fulltext not available.

Schwartz, Uwe, Németh, Attila, Diermeier, Sarah , Exler, Josef H., Hansch, Stefan, Maldonado, Rodrigo, Heizinger, Leonhard , Merkl, Rainer and Längst, Gernot (2018) Characterizing the nuclease accessibility of DNA in human cells to map higher order structures of chromatin. Nucleic Acids Research 2018 (1), pp. 1-16.

Beck, Alexander, Trippel, Franziska, Wagner, Alexandra, Joppien, Saskia, Felle, Max, Vokuhl, Christian, Schwarzmayr, Thomas, Strom, Tim M., von Schweinitz, Dietrich, Längst, Gernot and Kappler, Roland (2018) Overexpression of UHRF1 promotes silencing of tumor suppressor genes and predicts outcome in hepatoblastoma. Clinical Epigenetics 10 (1). Fulltext not available.

Kovač, Kristina , Sauer, Anja, Mačinković, Igor, Awe, Stephan, Finkernagel, Florian , Hoffmeister, Helen, Fuchs, Andreas , Müller, Rolf, Rathke, Christina, Längst, Gernot and Brehm, Alexander (2018) Tumour-associated missense mutations in the dMi-2 ATPase alters nucleosome remodelling properties in a mutation-specific manner. Nature Communications 9 (1). Fulltext not available.

Hoffmeister, Helen, Fuchs, Andreas , Erdel, Fabian , Pinz, Sophia, Gröbner-Ferreira, Regina, Bruckmann, Astrid, Deutzmann, Rainer, Schwartz, Uwe, Maldonado, Rodrigo, Huber, Claudia, Dendorfer, Anne-Sarah, Rippe, Karsten and Längst, Gernot (2017) CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality. Nucleic Acids Research 45 (18), pp. 10534-10554.

Längst, Gernot, König, Fabian and Schubert, Thomas E. O. (2017) The monoclonal S9.6 antibody exhibits highly variable binding affinities towards different R-loop sequences. PLoS ONE 12 (6), e0178875.

Maldonado, Rodrigo, Filarsky, Michael, Grummt, Ingrid and Längst, Gernot (2017) Purine– and pyrimidine–triple-helix-forming oligonucleotides recognize qualitatively different target sites at the ribosomal DNA locus. RNA 24 (3), pp. 371-380. Fulltext not available.

Längst, Gernot, Silberhorn, Elisabeth, Schwartz, Uwe, Löffler, Patrick , Schmitz, Samuel, Symelka, Anne , Koning-Ward, Tania de and Merkl, Rainer (2016) Plasmodium falciparum Nucleosomes Exhibit Reduced Stability and Lost Sequence Dependent Nucleosome Positioning. PLoS Pathogens 12 (12), e10060.

Nardocci, Gino, Simonet, Nicolas G. , Navarro, Cristina, Längst, Gernot and Alvarez, Marco (2016) Differential enrichment of TTF-I and Tip5 in the T-like promoter structures of the rDNA contribute to the epigenetic response of Cyprinus carpio during environmental adaptation. Biochemistry and Cell Biology 94 (4), pp. 315-321. Fulltext not available.

Längst, Gernot, Schrader, Anna, Gross, Thomas and Thalhammer, Verena (2015) Characterization of Dnmt1 Binding and DNA Methylation on Nucleosomes and Nucleosomal Arrays. PLoS ONE 10 (10), e0140076.

Längst, Gernot and Manelyte, Laura (2015) Chromatin remodelers: from function to dysfunction. Genes 2015 (6), pp. 299-324.

Friedrich, Ulrike, Datta, Shyamtanu, Schubert, Thomas, Plößl, Karolina, Schneider, Magdalena, Grassmann, Felix, Fuchshofer, Rudolf, Tiefenbach, Klaus-Jürgen, Längst, Gernot and Weber, Bernhard H. F. (2015) Synonymous variants in HTRA1 implicated in AMD susceptibility impair its capacity to regulate TGF-β signaling. Human Molecular Genetics 24, pp. 6361-6373. Fulltext not available.

Diermeier, Sarah Daniela Helena, Kolovos, Petros, Heizinger, Leonhard, Schwartz, Uwe, Georgomanolis, Theodore, Zirkel, Anne, Wedemann, Gero, Grosveld, Frank, Knoch, Tobias A., Merkl, Rainer, Cook, Peter R., Längst, Gernot and Papatonis, Argyris (2014) TNFα signalling primes chromatin for NF-κB binding and induces rapid and widespread nucleosome repositioning. Genome Biology 15 (12).

Längst, Gernot, Gross, Thomas, Strohner, Ralf and Manelyte, Laura (2014) Chromatin targeting signals nucleosome positioning mechanism and non-coding RNA mediated regulation of the chromatin remodeling complex NoRC. PLoS Genetics 10 (3), e1004157.

Diermeier, Sarah, Nemmeth, Attila, Rehli, Michael, Grummt, Ingrid and Längst, Gernot (2013) Chromatin-Specific Regulation of Mammalian rDNA Transcription by Clustered TTF-I Binding Sites. PLoS Genetics 9.

Kammel, Christine, Thomaier, Maren, Sørensen, Brian B., Schubert, Thomas, Längst, Gernot, Grasser, Marion and Grasser, Klaus D. (2013) Arabidopsis DEAD-box RNA helicase UAP56 interacts with both RNA and DNA as well as with mRNA export factors. PloS one 8 (3), e60644.

Zillner, Karina, Filarsky, Michael, Rachow, Katrin, Weinberger, Michael, Längst, Gernot and Németh, Attila (2013) Large-scale organization of ribosomal DNA chromatin is regulated by Tip5. Nucleic Acids Research 41 (10), pp. 5251-5262.

Pham, Thu-Hang, Minderjahn, Julia, Schmidl, Christian, Hoffmeister, Helen, Schmidhofer, Sandra, Chen, Wei, Längst, Gernot, Benner, Christopher and Rehli, Michael (2013) Mechanisms of in vivo binding site selection of the hematopoietic master transcription factor PU.1. Nucleic acids research 41 (13), pp. 6391-6402.

Felle, Max, Hoffmeister, Helen, Rothammer, Julia, Fuchs, Andreas, Exler, Josef H. and Längst, Gernot (2011) Nucleosomes protect DNA from DNA methylation in vivo and in vitro. Nucleic Acids Research 39, p. 6956.

Felle, Max, Joppien, Saskia, Németh, Attila, Diermeier, Sarah, Thalhammer, Verena, Dobner, Thomas, Kremmer, Elisabeth, Kappler, Roland and Längst, Gernot (2011) The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1. Nucleic Acids Research 39, p. 8355.

Manelyte, Laura and Längst, Gernot (2013) Chromatin Remodelers and Their Way of Action. In: Radzioch, Daniela, (ed.) Chromatin Remodelling. , p. 3. ISBN 978-953-51-1087-3.

Wernig-Zorc, Sara (2023) Gene regulation via nucleosome stability modulation and RNA:DNA triplex formation. PhD, Universität Regensburg.

Siegel, Michael F. (2022) Characterization of stable cell lines, inducibly co-expressing CHD3/4 with PU.1. PhD, Universität Regensburg.

Schwartz, Uwe (2021) Functional Chromatin Extraction: A method to study DNA accessibility in higher-order structures of chromatin. PhD, Universität Regensburg.

Maldonado, Rodrigo (2019) Characterization of Muscle Glycogen Synthase and its Association with RNA in Sertoli Cells. PhD, Universität Regensburg.

Carrasco Wong, Ivo (2019) Oxidative stress-induced epigenetic transcriptional memory as a mechanism of programmed endothelial dysfunction in large for gestational age newborn of women with obesity. PhD, Universität Regensburg.

Valenzuela Nieto, Guillermo Eduardo (2019) Study of genetic and epigenetic determinants of gene expression regulation for both SL genes in response to estrogen in common carp (Cyprinus carpio). PhD, Universität Regensburg.

Bartoschik, Tanja Astrid (2019) Development and validation of new approaches for quantitative intermolecular interaction analysis by MicroScale Thermophoresis under near-native experimental conditions. PhD, Universität Regensburg.

Araya Fuenzalida, Ingrid Carolina (2019) Functional characterization of HMGN5 in
chromatin architecture and gene expression. PhD, Universität Regensburg.

Gross, Thomas (2017) Characterization of the Chromatin Remodeling Enzyme Lymphoid-Specific Helicase. PhD, Universität Regensburg.

Vera Sepúlveda, Tamara Scarlett (2016) Differential gene expression of Piscirickettsia salmonis strains in adaptive response to different culture systems: a strategy to identify possible intracellular survival mechanisms and pathogenicity. PhD, Universität Regensburg.

Diermeier, Sarah Daniela Helena (2014) Local and global analysis of the structure-function relation in chromatin. PhD, Universität Regensburg.

Filarsky, Michael (2013) Exploring the role of structured DNA elements and their specific binders in genome regulation. PhD, Universität Regensburg.

Huber, Claudia (2013) Deposition, positioning and dynamics of H2A.Z in Saccharomyces cerevisiae. PhD, Universität Regensburg.

Nardocci, Gino Alberto (2013) Epigenetic regulation of Cyprinus carpio ribosomal cistron during the acclimatization process. PhD, Universität Regensburg.

Schubert, Thomas (2012) Df31 protein and snoRNAs maintain accessible higher order structures of chromatin. PhD, Universität Regensburg.

Schrader, Anna (2010) Molecular mechanisms of nucleosome positioning and DNA methylation in chromatin. PhD, Universität Regensburg.

Felle, Max (2010) DNA methylation in chromatin - complexes and mechanisms. PhD, Universität Regensburg.

Nitzsche, Alexandra (2010) Epigenetische Organisation des Cytomegalievirus-Genoms. PhD, Universität Regensburg.