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Anzahl der Einträge in dieser Kategorie: 55.

Artikel

Dejaco, Alexander , Dorn, Christoph , Lier, Constantin, Fleischmann, Daniel, Kratzer, Alexander, Habler, Katharina, Paal, Michael, Gruber, Michael , Rosenberger, Johanna und Kees, Martin G. (2024) Target-controlled dialysis for antibiotics (TCD-ABx). Intensive Care Medicine Experimental 12, S. 108.

Witowski, Andrea, Palmowski, Lars, Minichmayr, Iris K., Zeitlinger, Markus, Dorn, Christoph , Lier, Constantin, Adamzik, Michael, Nowak, Hartmuth und Rahmel, Tim (2024) Concentrations of ceftazidime and avibactam in bile fluid—a prospective phase IIb study. Journal of Antimicrobial Chemotherapy 79 (12), S. 3297-3302. Volltext nicht vorhanden.

Sanz-Codina, Maria, van Os, Wisse, Pham, Anh Duc, Jorda, Anselm, Wölf-Duchek, Michael, Bergmann, Felix, Lackner, Edith, Lier, Constantin, Coen van Hasselt, J. G., Minichmayr, Iris K., Dorn, Christoph , Zeitlinger, Markus und al Jalali, Valentin (2024) Target-site cefiderocol pharmacokinetics in soft tissues of healthy volunteers. Journal of Antimicrobial Chemotherapy 79 (12), S. 3281-3288.

Schatz, Lea Marie, Greppmair, Sebastian, Kunzelmann, Alexandra K., Starp, Johannes, Brinkmann, Alexander, Roehr, Anka, Frey, Otto, Hagel, Stefan, Dorn, Christoph , Zoller, Michael, Scharf, Christina, Wicha, Sebastian G. und Liebchen, Uwe (2024) Predictive performance of multi-model approaches for model-informed precision dosing of piperacillin in critically ill patients. International Journal of Antimicrobial Agents 64 (4), S. 107305.

Brummer, Christina, Singer, Katrin, Brand, Almut, Bruss, Christina, Renner, Kathrin, Herr, Wolfgang, Pukrop, Tobias, Dorn, Christoph , Hellerbrand, Claus, Matos, Carina und Kreutz, Marina (2024) Sex-Dependent T Cell Dysregulation in Mice with Diet-Induced Obesity. International Journal of Molecular Sciences 25 (15), S. 8234.

Lier, Constantin, Dejaco, Alexander , Kratzer, Alexander, Kees, Martin G. , Kees, Frieder und Dorn, Christoph (2024) Free serum concentrations of antibiotics determined by ultrafiltration: extensive evaluation of experimental variables. Bioanalysis, S. 1-10. Volltext nicht vorhanden.

Hosmann, Arthur, Moser, Miriam M, van Os, Wisse, Gramms, Leon, al Jalali, Valentin, Sanz Codina, Maria, Plöchl, Walter, Lier, Constantin, Kees, Frieder , Dorn, Christoph , Rössler, Karl, Reinprecht, Andrea und Zeitlinger, Markus (2024) Linezolid brain penetration in neurointensive care patients. Journal of Antimicrobial Chemotherapy, dkae025.

Dejaco, Alexander , Dorn, Christoph , Paal, Michael, Gruber, Michael , Graf, Bernhard M. und Kees, Martin G. (2024) Determination of glomerular filtration rate “en passant” after high doses of iohexol for computed tomography in intensive care medicine—a proof of concept. Frontiers in Pharmacology 15.

Wulkersdorfer, Beatrix, Bergmann, Felix, Amann, Lisa, Fochtmann-Frana, Alexandra, Al Jalali, Valentin, Kurdina, Elizaveta, Lackner, Edith, Wicha, Sebastian G, Dorn, Christoph , Schäfer, Bruno, Ihra, Gerald, Rath, Thomas, Radtke, Christine und Zeitlinger, Markus (2023) Effect of albumin substitution on pharmacokinetics of piperacillin/tazobactam in patients with severe burn injury admitted to the ICU. Journal of Antimicrobial Chemotherapy.

Greppmair, Sebastian, Brinkmann, Alexander, Roehr, Anka, Frey, Otto, Hagel, Stefan, Dorn, Christoph , Marsot, Amélie, El-Haffaf, Ibrahim, Zoller, Michael, Saller, Thomas, Zander, Johannes, Schatz, Lea Marie, Scharf, Christina, Briegel, Josef, Minichmayr, Iris K., Wicha, Sebastian G. und Liebchen, Uwe (2023) Towards model-informed precision dosing of piperacillin: multicenter systematic external evaluation of pharmacokinetic models in critically ill adults with a focus on Bayesian forecasting. Intensive Care Medicine.

Chen, Zhendong, Taubert, Max, Chen, Chunli, Dokos, Charalambos, Fuhr, Uwe, Weig, Thomas, Zoller, Michael, Heck, Suzette, Dimitriadis, Konstantinos, Terpolilli, Nicole, Kinast, Christina, Scharf, Christina, Lier, Constantin, Dorn, Christoph und Liebchen, Uwe (2023) Plasma and Cerebrospinal Fluid Population Pharmacokinetics of Vancomycin in Patients with External Ventricular Drain. Antimicrobial Agents and Chemotherapy. Volltext nicht vorhanden.

Sanz-Codina, Maria, Wicha, Sebastian G, Wulkersdorfer, Beatrix, Al Jalali, Valentin, Van Os, Wisse, Vossen, Matthias G, Bauer, Martin, Lackner, Edith, Dorn, Christoph und Zeitlinger, Markus (2022) Comparison of ultrafiltration and microdialysis for ceftriaxone protein-binding determination. Journal of Antimicrobial Chemotherapy. Volltext nicht vorhanden.

Jorda, Anselm , Wulkersdorfer, Beatrix, Schoergenhofer, Christian, Matzneller, Peter, Jalali, Valentin A. L., Bauer, Martin, Wölfl‐Duchek, Michael, Lackner, Edith, Dorn, Christoph , Jilma, Bernd und Zeitlinger, Markus (2022) Effect of the human endotoxin challenge on tedizolid tissue penetration. British Journal of Clinical Pharmacology, (accept.art.). Volltext nicht vorhanden.

Dorn, Christoph , Petroff, David, Kratzer, Alexander, Kees, Frieder, Kloft, Charlotte, Zeitlinger, Markus , Wrigge, Hermann und Simon, Philipp (2022) Tigecycline Soft Tissue Penetration in Obese and Non-obese Surgical Patients Determined by Using In Vivo Microdialysis. European Journal of Drug Metabolism and Pharmacokinetics 47, S. 749-755.

Jorda, Anselm , Wulkersdorfer, Beatrix, Schörgenhofer, Christian, Matzneller, Peter , Al Jalali, Valentin, Bauer, Martin , Wölf-Duchek, Michael, Lackner, Edith, Dorn, Christoph, Jilma, Bernd und Zeitlinger, Markus (2022) Influence of tedizolid on the cytokine response to the endotoxin challenge in healthy volunteers: a cross-over trial. Journal of Antimicrobial Chemotherapy. Volltext nicht vorhanden.

Rösch, Gundula, Muschter, Dominique, Taheri, Shahed , El Bagdadi, Karima, Dorn, Christoph, Meurer, Andrea, Zaucke, Frank, Schilling, Arndt F., Grässel, Susanne, Straub, Rainer H. und Jenei-Lanzl, Zsuzsa (2022) β2-Adrenoceptor Deficiency Results in Increased Calcified Cartilage Thickness and Subchondral Bone Remodeling in Murine Experimental Osteoarthritis. Frontiers in Immunology 12.

Schoretsanitis, Georgios, Haen, Ekkehard, Piacentino, Daria, Conca, Andreas, Endres, Katharina, Hiemke, Christoph, Gründer, Gerhard und Paulzen, Michael (2022) Effects of body weight, smoking status, and sex on plasma concentrations of once-monthly paliperidone palmitate. Expert Review of Clinical Pharmacology 15 (2), S. 243-249. Volltext nicht vorhanden.

Busse, David, Simon, Philipp, Schmitt, Lisa, Petroff, David, Dorn, Christoph , Dietrich, Arne, Zeitlinger, Markus, Huisinga, Wilhelm, Michelet, Robin, Wrigge, Hermann und Kloft, Charlotte (2021) Comparative Plasma and Interstitial Tissue Fluid Pharmacokinetics of Meropenem Demonstrate the Need for Increasing Dose and Infusion Duration in Obese and Non-obese Patients. Clinical Pharmacokinetics.

Rösch, Gundula, El Bagdadi, Karima, Muschter, Dominique , Taheri, Shahed, Dorn, Christoph , Meurer, Andrea, Straub, Rainer H. , Zaucke, Frank , Schilling, Arndt F., Grässel, Susanne und Jenei-Lanzl, Zsuzsa (2021) Sympathectomy aggravates subchondral bone changes during osteoarthritis progression in mice without affecting cartilage degeneration or synovial inflammation. Osteoarthritis and Cartilage 30 (3), S. 461-474. Volltext nicht vorhanden.

Busse, David, Borghardt, Jens Markus, Petroff, David, Pevzner, Alice, Dorn, Christoph , El‐Najjar, Nahed, Huisinga, Wilhelm, Wrigge, Hermann, Simon, Philipp und Kloft, Charlotte (2021) EVALUATING PREDICTION METHODS FOR GLOMERULAR FILTRATION TO OPTIMISE DRUG DOSES IN OBESE AND NON‐OBESE PATIENTS. British Journal of Clinical Pharmacology. Volltext nicht vorhanden.

Busse, David , Simon, Philipp , Petroff, David, Dorn, Christoph, Schmitt, Lisa, Bindellini, Davide, Kratzer, Alexander, Dietrich, Arne, Zeitlinger, Markus, Huisinga, Wilhelm , Michelet, Robin , Wrigge, Hermann und Kloft, Charlotte (2021) Similar Piperacillin/Tazobactam Target Attainment in Obese versus Nonobese Patients despite Differences in Interstitial Tissue Fluid Pharmacokinetics. Pharmaceutics 13 (9), S. 1380.

Schießer, Selina, Hitzenbichler, Florian, Kees, Martin Georg, Kratzer, Alexander, Lubnow, Matthias , Salzberger, Bernd , Kees, Frieder und Dorn, Christoph (2021) Measurement of Free Plasma Concentrations of Beta-Lactam Antibiotics. Therapeutic Drug Monitoring 43 (2), S. 264-270. Volltext nicht vorhanden.

Dorn, Christoph , Petroff, David, Stoelzel, Melanie, Kees, Martin G. , Kratzer, Alexander, Dietrich, Arne, Kloft, Charlotte, Zeitlinger, Markus, Kees, Frieder , Wrigge, Hermann und Simon, Philipp (2021) Perioperative administration of cefazolin and metronidazole in obese and non-obese patients: a pharmacokinetic study in plasma and interstitial fluid. Journal of Antimicrobial Chemotherapy. Volltext nicht vorhanden.

Wulkersdorfer, Beatrix, Wicha, Sebastian G., Kurdina, Elizaveta, Carrion Carrera, Stephan F., Matzneller, Peter, Al Jalali, Valentin, Vossen, Matthias G., Riesenhuber, Sonja, Lackner, Edith, Dorn, Christoph und Zeitlinger, Markus (2021) Protein binding of clindamycin in vivo by means of intravascular microdialysis in healthy volunteers. Journal of Antimicrobial Chemotherapy. Volltext nicht vorhanden.

Dorn, Christoph , Schießer, Selina, Wulkersdorfer, Beatrix, Hitzenbichler, Florian, Kees, Martin G. und Zeitlinger, Markus (2020) Determination of free clindamycin, flucloxacillin or tedizolid in plasma: Keep attention to physiological conditions when using ultrafiltration. Biomedical Chromatography 34, e4820.

Ullah, Sami, Beer, Ronny, Fuhr, Uwe, Taubert, Max , Zeitlinger, Markus, Kratzer, Alexander, Dorn, Christoph, Arshad, Usman, Kofler, Mario und Helbok, Raimund (2020) Brain Exposure to Piperacillin in Acute Hemorrhagic Stroke Patients Assessed by Cerebral Microdialysis and Population Pharmacokinetics. Neurocritical Care.

Liebchen, Uwe, Dorn, Christoph , Kees, Martin, Schiesser, Selina, Hitzenbichler, Florian, Kees, Frieder und Paal, Michael (2020) Comment on “Meropenem, Cefepime, and Piperacillin Protein Binding in Patient Samples”. Therapeutic Drug Monitoring 42 (6), S. 909-910. Volltext nicht vorhanden.

Sommer, Judith, Dorn, Christoph , Gäbele, Erwin, Bataille, Frauke, Freese, Kim, Seitz, Tatjana, Thasler, Wolfgang E., Büttner, Reinhard, Weiskirchen, Ralf , Bosserhoff, Anja und Hellerbrand, Claus (2020) Four-And-A-Half LIM-Domain Protein 2 (FHL2) Deficiency Aggravates Cholestatic Liver Injury. Cells 9 (1), S. 248.

Simon, Philipp , Busse, David , Petroff, David , Dorn, Christoph , Ehmann, Lisa, Hochstädt, Sophie, Girrbach, Felix, Dietrich, Arne, Zeitlinger, Markus, Kees, Frieder, Kloft, Charlotte und Wrigge, Hermann (2020) Linezolid Concentrations in Plasma and Subcutaneous Tissue are Reduced in Obese Patients, Resulting in a Higher Risk of Underdosing in Critically Ill Patients: A Controlled Clinical Pharmacokinetic Study. Journal of Clinical Medicine 9 (4), S. 1067.

Simon, Philipp, Petroff, David, Busse, David , Heyne, Jana, Girrbach, Felix, Dietrich, Arne, Kratzer, Alexander Ludwig, Zeitlinger, Markus, Kloft, Charlotte, Kees, Frieder, Wrigge, Hermann und Dorn, Christoph (2020) Meropenem Plasma and Interstitial Soft Tissue Concentrations in Obese and Nonobese Patients—A Controlled Clinical Trial. Antibiotics 9 (12), S. 931.

Busse, David , Simon, Philipp, Michelet, Robin , Ehmann, Lisa, Mehner, Frank, Dorn, Christoph , Kratzer, Alexander, Huisinga, Wilhelm, Wrigge, Hermann , Petroff, David und Kloft, Charlotte (2020) Quantification of microdialysis related variability in humans: Clinical trial design recommendations. European Journal of Pharmaceutical Sciences, S. 105607. Volltext nicht vorhanden.

Ehmann, L., Simon, P., Busse, D., Petroff, D., Dorn, Christoph , Huisinga, W., Dietrich, A., Zeitlinger, M., Wrigge, H. und Kloft, C. (2020) Risk of target non-attainment In obese compared to non-obese patients In Calculated linezolid therapy. Clinical Microbiology and Infection. Volltext nicht vorhanden.

Dorn, Christoph, Petroff, David, Neumann, Nancy, Kratzer, Alexander, El-Najjar, Nahed , Dietrich, Arne, Kloft, Charlotte, Zeitlinger, Markus , Kees, Martin, Kees, Frieder, Wrigge, Hermann und Simon, Philipp (2019) Plasma and tissue pharmacokinetics of fosfomycin in morbidly obese and non-obese surgical patients: a controlled clinical trial. Journal of Antimicrobial Chemotherapy. Volltext nicht vorhanden.

Kratzer, Alexander, Rothe, Ulrich, Kees, Frieder und Dorn, Christoph (2019) Stabilität von Ceftolozan/Tazobactam in Infusionslösungen für die verlängerte oder kontinuierliche Applikation. Krankenhauspharmazie 40 (4), S. 195-200. Volltext nicht vorhanden.

Dorn, Christoph , Kratzer, Alexander Ludwig, Schießer, Selina, Kees, Frieder , Wrigge, Hermann und Simon, Philipp (2019) Determination of total or free cefazolin and metronidazole in human plasma or interstitial fluid by HPLC-UV for pharmacokinetic studies in man. Journal of Chromatography B. Volltext nicht vorhanden.

Nussbaumer-Pröll, Alina Karoline, Eberl, Sabine, Reiter, Birgit, Stimpfl, Thomas, Dorn, Christoph und Zeitlinger, Markus (2019) Low pH reduces the activity of ceftolozane/tazobactam in human urine, but confirms current breakpoints for urinary tract infections. Journal of Antimicrobial Chemotherapy. Volltext nicht vorhanden.

Simon, P., Petroff, D., Dorn, Christoph , Ehmann, L., Kloft, C., Prettin, C., Dietrich, A., Zeitlinger, M., Kees, F. und Wrigge, H. (2019) Measurement of soft tissue drug concentrations in morbidly obese and non-obese patients – A prospective, parallel group, open-labeled, controlled, phase IV, single center clinical trial. Contemporary Clinical Trials Communications 15, S. 100375. Volltext nicht vorhanden.

Nowak, Hartmuth, Weidemann, Caroline, Martini, Stefan, Oesterreicher, Zoe Anne, Dorn, Christoph, Adamzik, Michael, Kees, Frieder, Zeitlinger, Markus und Rahmel, Tim (2019) Repeated determination of moxifloxacin concentrations in interstitial space fluid of muscle and subcutis in septic patients. Journal of Antimicrobial Chemotherapy. Volltext nicht vorhanden.

Burau, Daniela, Petroff, David, Simon, Philipp, Ehmann, Lisa, Weiser, Christine, Dorn, Christoph , Kratzer, Alexander, Wrigge, Hermann und Kloft, Charlotte (2018) Drug combinations and impact of experimental conditions on relative recovery in in vitro microdialysis investigations. European Journal of Pharmaceutical Sciences. Volltext nicht vorhanden.

Kratzer, Alexander, Schießer, Selina, Matzneller, Peter, Wulkersdorfer, Beatrix, Zeitlinger, Markus , Schlossmann, Jens , Kees, Frieder und Dorn, Christoph (2018) Determination of Total and Free Ceftolozane and Tazobactam in Human Plasma and Interstitial Fluid by HPLC-UV. Journal of Pharmaceutical and Biomedical Analysis. Volltext nicht vorhanden.

Dorn, Christoph, Kratzer, Alexander, Liebchen, Uwe, Schleibinger, Michael, Murschhauser, Alexandra, Schlossmann, Jens , Kees, Frieder, Simon, Philipp und Kees, Martin G. (2018) Impact of Experimental Variables on the Protein Binding of Tigecycline in Human Plasma as Determined by Ultrafiltration. Journal of Pharmaceutical Sciences 107 (2), S. 739-744. Volltext nicht vorhanden.

Dorn, Christoph , Nowak, Hartmuth, Weidemann, Caroline, Martini, Stefan, Zeitlinger, Markus, Adamzik, Michael und Kees, Frieder K. (2017) Decreased protein binding of moxifloxacin in patients with sepsis? GMS Infectious Diseases 2017 (5), Doc03.

Kratzer, Alexander, Kees, Frieder und Dorn, Christoph (2016) Unbound fraction of fluconazole and linezolid in human plasma as determined by ultrafiltration: Impact of membrane type. Journal of Chromatography B 1039, S. 74-78. Volltext nicht vorhanden.

Arndt, Stephanie, Wacker, Eva, Dorn, Christoph, Koch, Andreas, Saugspier, Michael, Thasler, W. E., Hartmann, Arndt, Bosserhoff, Anja-Katrin und Hellerbrand, Claus (2015) Enhanced expression of BMP6 inhibits hepatic fibrosis in non-alcoholic fatty liver disease. Gut 64 (6), S. 973-981.

Dorn, Christoph , Heilmann, Jörg und Hellerbrand, Claus (2012) Protective effect of xanthohumol on toxin-induced liver inflammation and fibrosis. International Journal of Clinical and Experimental Pathology 5 (1), S. 29-36.

Klein, Matthias S. , Dorn, Christoph, Saugspier, Michael Sebastian, Hellerbrand, Claus, Oefner, Peter J. und Gronwald, Wolfram (2011) Discrimination of steatosis and NASH in mice using nuclear magnetic resonance spectroscopy. Metabolomics 7 (2), S. 237-246. Volltext nicht vorhanden.

Gäbele, Erwin, Dostert, Karin, Dorn, Christoph , Patsenker, Eleonora, Stickel, Felix und Hellerbrand, Claus (2011) A New Model of Interactive Effects of Alcohol and High-Fat Diet on Hepatic Fibrosis. Alcoholism: Clinical and Experimental Research 35 (7), S. 1361-1367. Volltext nicht vorhanden.

Wanninger, Josef, Neumeier, Markus, Bauer, Sabrina, Weiss, Thomas S. , Eisinger, Kristina, Walter, Roland, Dorn, Christoph , Hellerbrand, Claus, Schäffler, Andreas und Buechler, Christa (2011) Adiponectin induces the transforming growth factor decoy receptor BAMBI in human hepatocytes. FEBS Letters 585 (9), S. 1338-1344. Volltext nicht vorhanden.

Henkel, Janin, Gärtner, Daniela, Dorn, Christoph , Hellerbrand, Claus, Schanze, Nancy, Elz, Sheila R. und Püschel, Gerhard P. (2011) Oncostatin M produced in Kupffer cells in response to PGE2: possible contributor to hepatic insulin resistance and steatosis. Laboratory Investigation 91 (7), S. 1107-1117. Volltext nicht vorhanden.

Patsenker, Eleonora, Schneider, Vreni, Ledermann, Monika, Saegesser, Hans, Dorn, Christoph , Hellerbrand, Claus und Stickel, Felix (2011) Potent antifibrotic activity of mTOR inhibitors sirolimus and everolimus but not of cyclosporine A and tacrolimus in experimental liver fibrosis. Journal of Hepatology 55 (2), S. 388-398. Volltext nicht vorhanden.

Bauer, Sabrina, Wanninger, Josef, Schmidhofer, Sandra, Weigert, Johanna, Neumeier, Markus, Dorn, Christoph , Hellerbrand, Claus, Zimara, Nicole, Schäffler, Andreas, Aslanidis, Charalampos und Buechler, Christa (2011) Sterol Regulatory Element-Binding Protein 2 (SREBP2) Activation after Excess Triglyceride Storage Induces Chemerin in Hypertrophic Adipocytes. Endocrinology 152 (1), S. 26-35. Volltext nicht vorhanden.

Kirovski, Georgi, Gäbele, Erwin, Dorn, Christoph , Moleda, Lukas, Niessen, Christoph, Weiss, Thomas S. , Wobser, Hella, Schacherer, Doris, Buechler, Christa , Wasmuth, Hermann E. und Hellerbrand, Claus (2010) Hepatic steatosis causes induction of the chemokine RANTES in the absence of significant hepatic inflammation. International Journal of Clinical and Experimental Pathology 3 (7), S. 675-680.

Dorn, Christoph , Riener, Marc-Oliver, Kirovski, Georgi, Saugspier, Michael, Steib, Kathrin, Weiss, Thomas S. , Gäbele, Erwin, Kristiansen, Glen, Hartmann, Arndt und Hellerbrand, Claus (2010) Expression of fatty acid synthase in nonalcoholic fatty liver disease. International Journal of Clinical and Experimental Pathology 3 (5), S. 505-514.

Dorn, Christoph , Bataille, Frauke, Gaebele, Erwin, Heilmann, Jörg und Hellerbrand, Claus (2010) Xanthohumol feeding does not impair organ function and homoeostasis in mice. Food and Chemical Toxicology 48 (7), S. 1890-1897. Volltext nicht vorhanden.

Buchkapitel

Dorn, Christoph (2021) 3.3. Informationen über Arzneimittel. In: Sax, Michael, (ed.) Pharmazie für die Praxis : Lehrbuch für Pharmazeuten im Praktikum : Handbuch für die Apotheke. Deutscher Apotheker Verlag, Stuttgart, S. 152-173. ISBN 978-3-7692-7010-5. Volltext nicht vorhanden.

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