Startseite UR
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Schorr, Kathrin
, Konrad, Johannes
, Birringer, Jan
, Damm, Carsten
, Breunig, Miriam
und Goepferich, Achim
(2026)
A refined coadministration regime to mitigate immunological clearance of biomedical nanoparticles.
European Journal of Pharmaceutics and Biopharmaceutics 221, S. 114989.
Birringer, Jan, Konrad, Johannes, Melchner, Stephan, Remmert, Marius und Goepferich, Achim
(2025)
Coumarin‐Caged Nanoparticle for Light‐Driven Surface Modification.
ChemMedChem, e202500636.
Damm, Carsten und Goepferich, Achim
(2025)
Dual cross-linked hydrogels as promising materials for drug delivery.
International Journal of Pharmaceutics 683, S. 125929.
Remmert, Marius, Konrad, Johannes
, Birringer, Jan
und Goepferich, Achim
(2025)
Interferon gamma modifies nanoparticle tropism and cell uptake.
Journal of Drug Delivery Science and Technology 113, S. 107301.
Bresinsky, Melanie und Goepferich, Achim
(2025)
Control of biomedical nanoparticle distribution and drug release in vivo by complex particle design strategies.
European Journal of Pharmaceutics and Biopharmaceutics 208, S. 114634.
Lang, Johannes, Schorr, Kathrin und Goepferich, Achim
(2024)
Towards a switchable nanoparticle behavior using inverse electron-demand Diels-Alder chemistry and ectoenzyme-based ligand activation.
European Journal of Pharmaceutical Sciences 204, S. 106944.
Schorr, Kathrin, Chen, Xinyu, Sasaki, Takanori, Arias-Loza, Anahi Paula, Lang, Johannes, Higuchi, Takahiro und Goepferich, Achim
(2024)
Rethinking Thin-Layer Chromatography for Screening Technetium-99m Radiolabeled Polymer Nanoparticles.
ACS Pharmacology & Translational Science 7 (9), S. 2604-2611.
Walter, Melanie, Bresinsky, Merlin, Zimmer, Oliver
, Pockes, Steffen
und Goepferich, Achim
(2024)
Conditional Cell-Penetrating Peptide Exposure as Selective Nanoparticle Uptake Signal.
ACS Applied Materials & Interfaces 16 (29), S. 37734-37747.
Mietzner, Raphael
, Barbey, Clara, Lehr, Heike, Ziegler, Christian E., Peterhoff, David
, Wagner, Ralf
, Goepferich, Achim
und Breunig, Miriam
(2024)
Prolonged delivery of HIV-1 vaccine nanoparticles from hydrogels.
International Journal of Pharmaceutics 657, S. 124131.
Zimmer, Oliver
und Goepferich, Achim
(2024)
On the uncertainty of the correlation between nanoparticle avidity and biodistribution.
European Journal of Pharmaceutics and Biopharmaceutics 198, S. 114240.
Bohley, Marilena
, Dillinger, Andrea E., Braunger, Barbara M., Tamm, Ernst R. und Goepferich, Achim
(2023)
Intravenous injection of cyclosporin A loaded lipid nanocapsules fights inflammation and immune system activation in a mouse model of diabetic retinopathy.
Drug Delivery and Translational Research 13, S. 2807-2818.
und Goepferich, Achim
(2023)
How clathrin-coated pits control nanoparticle avidity for cells.
Nanoscale Horizons 8 (2), S. 256-269.
Volltext nicht vorhanden.
Zimmer, Oliver
und Goepferich, Achim
(2022)
How clathrin-coated pits control nanoparticle avidity for cells.
Nanoscale Horizons, (Advance Art.).
Bohley, Marilena, Dillinger, Andrea E., Schweda, Frank, Ohlmann, Andreas, Braunger, Barbara M., Tamm, Ernst R. und Goepferich, Achim
(2022)
A single intravenous injection of cyclosporin A–loaded lipid nanocapsules prevents retinopathy of prematurity.
Science Advances 8 (38).
Ziegler, Christian, Graf, Moritz, Nagaoka, Makoto und Goepferich, Achim
(2022)
Investigation of the Impact of Hydrolytically Cleavable Groups on the Stability of Poly(ethylene glycol) Based Hydrogels Cross-Linked via the Inverse Electron Demand Diels-Alder (iEDDA) Reaction.
Macromolecular Bioscience 22 (12), S. 2200226.
und Goepferich, Achim
(2022)
Enzyme-triggered antigen release enhances cross presentation by dendritic cells.
Nanomedicine: Nanotechnology, Biology, and Medicine 42, S. 102545.
Volltext nicht vorhanden.
, Dillinger, Andrea E., Tamm, Ernst R.
und Goepferich, Achim
(2022)
Targeted drug delivery to the retinal pigment epithelium: Untapped therapeutic potential for retinal diseases.
Drug Discovery Today 27 (9), S. 2497-2509.
Volltext nicht vorhanden.
Mietzner, Raphael
, Pawlak, Ramona
, Tamm, Ernst R., Goepferich, Achim
, Fuchshofer, Rudolf
und Breunig, Miriam
(2021)
Angiopoietin-1 Mimetic Nanoparticles for Restoring the Function of Endothelial Cells as Potential Therapeutic for Glaucoma.
Pharmaceuticals 15 (1), S. 18.
Maslanka Figueroa, Sara
, Fleischmann, Daniel, Beck, Sebastian, Tauber, Philipp, Witzgall, Ralph, Schweda, Frank und Goepferich, Achim
(2020)
Nanoparticles Mimicking Viral Cell Recognition Strategies Are Superior Transporters into Mesangial Cells.
Advanced Science 7 (11), S. 1903204.
Goepferich, Achim
, Maslanka-Figueroa, Sara, Fleischmann, Daniel und Beck, Sebastian
(2020)
Thermodynamic, Spatial and Methodological Considerations for the Manufacturing of Therapeutic Polymer Nanoparticles.
Pharmaceutical Research 37 (59).
(2020)
Adenovirus-Mimetic Nanoparticles: Sequential Ligand-Receptor Interplay as a Universal Tool for Enhanced In Vitro/In Vivo Cell Identification.
ACS Applied Materials & Interfaces 12 (31), S. 34689-34702.
Volltext nicht vorhanden.
Abdellatif, Ahmed
, Hennig, Robert, Pollinger, Klaus, Tawfeek, Hesham und Goepferich, Achim
(2020)
Fluorescent Nanoparticles Coated with a Somatostatin Analogue Target Blood Monocyte for Efficient Leukaemia Treatment.
Pharmaceutical Research 37 (11), S. 2017.
Maslanka-Figueroa, Sara
, Fleischmann, Daniel, Beck, Sebastian und Goepferich, Achim
(2020)
The Effect of Ligand Mobility on the Cellular Interaction of Multivalent Nanoparticles.
Macromolecular Bioscience 20, S. 900427.
und Goepferich, Achim
(2019)
Hydrogel microspheres evading alveolar macrophages for sustained pulmonary protein delivery.
nternational Journal of Pharmaceutics 566, S. 652-661.
Volltext nicht vorhanden.
, Gregoritza, Manuel
und Goepferich, Achim
(2018)
Ligand Density and Linker Length are Critical Factors for Multivalent Nanoparticle−Receptor Interactions.
ACS Applied Materials & Interfaces 11 (1), S. 1311-1320.
Volltext nicht vorhanden.
(2018)
Hydrogel wound dressing for bioactive treatment of acute and chronic wounds.
European Polymer Journal 100, S. 1-11.
Volltext nicht vorhanden.
(2017)
Polyanion based controlled release system for the GnRH-receptor antagonist degarelix.
European Journal of Pharmaceutical Sciences 104, S. 65-71.
Volltext nicht vorhanden.
und Fuchshofer, Rudolf
(2016)
Cyclic RGD peptides target human trabecular meshwork cells while ameliorating connective tissue growth factor-induced fibrosis.
Journal of Drug Targeting 24 (10), S. 952-959.
Volltext nicht vorhanden.
(2016)
Determination of the activity of maleimide-functionalized phospholipids during preparation of liposomes.
International Journal of Pharmaceutics 514, S. 93-102.
Volltext nicht vorhanden.
(2016)
HPLC analysis as a tool for assessing targeted liposome composition.
International Journal of Pharmaceutics 497 (1-2), S. 293-300.
Volltext nicht vorhanden.
und Brandl, Ferdinand
(2016)
Polyanions effectively prevent protein conjugation and activity loss during hydrogel cross-linking.
Journal of Controlled Release 238, S. 92-102.
Volltext nicht vorhanden.
, Giessibl, Franz J.
, Goepferich, Achim
und Breunig, Miriam
(2015)
Oligolayer-Coated Nanoparticles: Impact of Surface Topography at the Nanobio Interface.
ACS applied materials & interfaces 7, S. 7891-7900.
Volltext nicht vorhanden.
(2015)
Branched Polymer–Drug Conjugates for Multivalent Blockade of Angiotensin II Receptors.
Molecular Pharmaceutics 12 (9), S. 3292-3302.
Volltext nicht vorhanden.
, Grassi, Mario und Brandl, Ferdinand
(2015)
Diels–Alder hydrogels for controlled antibody release: Correlation between mesh size and release rate.
Molecular Pharmaceutics 12 (9), S. 3358-3368.
Volltext nicht vorhanden.
, Staffel, Janina, Pollinger, Klaus, Haunberger, Alexandra, Breunig, Miriam
, Schweda, Frank, Tamm, Ernst R.
und Goepferich, Achim
(2015)
Multivalent nanoparticles bind the retinal and choroidal vasculature.
Journal of Controlled Release 220 (Part A), S. 265-274.
Volltext nicht vorhanden.
(2015)
Nanoparticles for the treatment of ocular neovascularizations.
European Journal of Pharmaceutics and Biopharmaceutics 95 (Part B), S. 294-306.
Volltext nicht vorhanden.
Kirchhof, Susanne, Strasser, Andrea, Wittmann, Hans-Joachim, Messmann, Viktoria, Hammer, Nadine, Goepferich, Achim und Brandl, Ferdinand
(2015)
New insights into the cross-linking and degradation mechanism of Diels–Alder hydrogels.
Journal of Materials Chemistry B 3, S. 449-457.
(2015)
Protein compatibility of selected cross-linking reactions for hydrogels.
Macromol. Biosci. 15 (3), S. 405-413.
Volltext nicht vorhanden.
Herrnberger, Leonie, Hennig, Robert, Kremer, Werner, Hellerbrand, Claus, Goepferich, Achim
, Kalbitzer, Hans Robert und Tamm, Ernst R.
(2014)
Formation of Fenestrae in Murine Liver Sinusoids Depends on Plasmalemma Vesicle-Associated Protein and Is Required for Lipoprotein Passage.
PLoS ONE 9 (12), e115005.
und Goepferich, Achim
(2014)
Nanoparticle multivalency counterbalances the ligand affinity loss upon PEGylation.
Journal of Controlled Release 194, S. 20-27.
Volltext nicht vorhanden.
(2014)
Cleavable carbamate linkers for controlled protein delivery from hydrogels.
Journal of Controlled Release 183, S. 67-76.
Volltext nicht vorhanden.
, Schoeberl, Simon, Strauss, O., Luschmann, Karl und Goepferich, Achim
(2014)
Self-assembling colloidal system for the ocular administration of cyclosporine A.
Cornea 33 (1), S. 77-81.
Volltext nicht vorhanden.
, Simon, Ole, Goepferich, Achim
, Wegner, Henny, Moeller, Marcus J., Rumpel, Elisabeth, Kotb, Ahmed und Endlich, Karlhans
(2014)
Two-Photon Microscopy Reveals Stationary Podocytes in Living Zebrafish Larvae.
Journal of the American Society of Nephrology 25 (4), S. 681-686.
Volltext nicht vorhanden.
, Schoeberl, Simon, Framme, Carsten, Luschmann, Karl und Goepferich, Achim
(2013)
Developing an in situ nanosuspension: A novel approach towards the efficient administration of poorly soluble drugs at the anterior eye.
European Journal of Pharmaceutical Sciences 50 (3-4), S. 385-392.
Volltext nicht vorhanden.
(2013)
Drug Loading of Polymerics Micelles.
Pharmaceutical Research 30 (2), S. 484-595.
Volltext nicht vorhanden.
, Rachel, Reinhard, Rischer, M., Engel, J., Backofen, Michael und Goepferich, Achim
(2013)
Impact of Polyelectrolyte Structure on the Shape of Nanoassemblies with Cationic Peptides.
European Journal of Pharmaceutical Sciences 102, S. 2599-2607.
Volltext nicht vorhanden.
, Zellner, Johannes
, Englert, Carsten
, Prantl, Lukas, Kujat, Richard, Nerlich, Michael und Angele, Peter
(2013)
Insulin is essential for in vitro chondrogenesis of mesenchymal progenitor cells and influences chondrogenesis in a dose-dependent manner.
International Orthopaedics 37 (1), S. 153-158.
Volltext nicht vorhanden.
, Wenzel, Rebecca, Breunig, Miriam
, Tessmar, Joerg
, Tamm, Ernst R.
und Goepferich, Achim
(2013)
Ligand-functionalized nanoparticles target endothelial cells in retinal capillaries after systemic application.
Proceedings of the National Academy of Sciences of the United States of America (PNAS) 110 (15), S. 6115-6120.
Volltext nicht vorhanden.
(2013)
Pharmacokinetics, biocompatibility and bioavailability of a controlled release monoclonal antibody formulation.
Journal of Controlled Release 172 (3), S. 975-982.
Volltext nicht vorhanden.
(2013)
Premature drug release of polymeric micelles and its effects on tumor targeting.
International Journal of Pharmaceutics 445 (1-2), S. 117-124.
Volltext nicht vorhanden.
(2013)
Protein-Polyanion Interactions for the Controlled Release of Monoclonal Antibodies.
Biomacromolecules 14 (1), S. 75-83.
Volltext nicht vorhanden.
, Wagenknecht, Hans-Achim und Breunig, Miriam
(2013)
RNA “Traffic Lights”: An Analytical Tool to Monitor siRNA Integrity.
ACS chemical biology 8, S. 890-894.
Volltext nicht vorhanden.
und Breunig, Miriam
(2012)
A library of strictly linear poly(ethylene glycol)-poly(ethylene imine) diblock coploymers to perform structure-function relationship on non-viral gene carriers.
Journal of Controlled Release 162, S. 446-455.
Volltext nicht vorhanden.
(2012)
Analysis of Immediate Stress Mechanisms upon Injection of Polymeric Micelles and Related Colloidal Drug Carriers.
Biomacromolecules 13 (6), S. 1707-1718.
Volltext nicht vorhanden.
, Teßmar, Jörg
, Ohlmann, Andreas
, Tamm, Ernst R.
, Witzgall, Ralph
und Goepferich, Achim
(2012)
Kidney Podocytes as Specific Targets for cyclo(RGDfC)-Modified Nanoparticles.
Small 8, S. 3368-3375.
Volltext nicht vorhanden.
und Breunig, Miriam
(2012)
Layer-by-Layer Coated Gold Nanoparticles: Size-Dependent Delivery of DNA into Cells.
Small 8 (24), S. 3847-3856.
Volltext nicht vorhanden.
(2012)
Targeting drugs to mitochondria.
European Journal of Pharmaceutics and Biopharmaceutics 82, S. 1-18.
Volltext nicht vorhanden.
und Maeder, K.
(2011)
How Stealthy are PEG-PLA Nanoparticles? An NIR In Vivo Study Combined with Detailed Size Measurements.
Pharmaceutical Research 28 (8), S. 1995-2007.
Volltext nicht vorhanden.
, Rischer, M., Engl, J. und Goepferich, Achim
(2011)
Nanofibres Resulating from Cooperative Electrostatic and Hydrophobic Interactions between Peptides and Polyelectrolytes of Opposite Charge.
Langmuir 27, S. 14450-14459.
Volltext nicht vorhanden.
, Kuntsche, J. und Maeder, K.
(2011)
Tumor Accumulation of NIR Fluorescent PEG PLA Nanoparticles: Impact of Particle Size and Human Xenograft Tumor Model.
ACS Nano 5, S. 8710-8720.
Volltext nicht vorhanden.
, Cabrele, Chiara
, Keller, Max, Pluym, Nicola
, Buschauer, Armin, Rachel, Reinhard, Tessmar, Joerg
, Breunig, Miriam
und Goepferich, Achim
(2010)
G protein-coupled receptors function as logic gates for nanoparticle binding and cell uptake.
Proceedings of the National Academy of Sciences USA: PNAS 107 (23), S. 10667-10672.
Volltext nicht vorhanden.
und Breunig, Miriam
(2009)
Layer-by-layer assembled gold nanoparticles for siRNA delivery.
Nano letters 9 (5), S. 2059-2064.
Volltext nicht vorhanden.
, Gabel, Veit-Peter, Blunk, Torsten und Goepferich, Achim
(2007)
Ascorbic Acid Modulates Proliferation and Extracellular Matrix Accumulation of Hyalocytes.
Tissue Engineering 13 (6), S. 1281-1289.
Volltext nicht vorhanden.
, Lungwitz, Uta, Liebl, Renate und Goepferich, Achim
(2007)
Breaking up the correlation between efficacy and toxicity for nonviral gene delivery.
Proceedings of the National Academy of Sciences 104 (36), S. 14454-14459.
Volltext nicht vorhanden.
, Staudenmaier, Rainer, Wenzel, Magdalene M., Goepferich, Achim
und Blunk, Torsten
(2007)
In VitroandIn VivoCartilage Engineering Using a Combination of Chondrocyte-Seeded Long-Term Stable Fibrin Gels and Polycaprolactone-Based Polyurethane Scaffolds.
Tissue Engineering 13 (9), S. 2207-2218.
Volltext nicht vorhanden.
, Maier, Gerhard, Wenzel, Magdalene, Staudenmaier, Rainer, Goepferich, Achim
und Blunk, Torsten
(2007)
Long-term stable fibrin gels for cartilage engineering.
Biomaterials 28 (1), S. 55-65.
Volltext nicht vorhanden.
, Breunig, M.
, Tessmar, J. und Goepferich, Achim
(2007)
Poly(ethylene glycol) based hydrogels for intraocular applications.
Advanced Engineering Materials 9 (12), S. 1141-1149.
Volltext nicht vorhanden.
(2007)
Rational design of hydrogels for tissue engineering: Impact of physical factors on cell behavior.
Biomaterials 28 (2), S. 134-146.
Volltext nicht vorhanden.
, Goepferich, Achim
und Mikos, Antonios G.
(2007)
Synthesis and in Vitro Hydroxyapatite Binding of Peptides Conjugated to Calcium-Binding Moieties.
Biomacromolecules 8 (7), S. 2237-2243.
Volltext nicht vorhanden.
, Lungwitz, Uta, Liebl, Renate und Goepferich, Achim
(2006)
Fluorescence resonance energy transfer: Evaluation of the intracellular stability of polyplexes.
European Journal of Pharmaceutics and Biopharmaceutics 63 (2), S. 156-165.
Volltext nicht vorhanden.
, Bauer-Kreisel, Petra, Weiser, Barbara, Fischbach, Claudia
, Schulz, Michaela B, Goepferich, Achim
und Blunk, Torsten
(2005)
Adipose Tissue Engineering Based on Mesenchymal Stem Cells and Basic Fibroblast Growth Factorin Vitro.
Tissue Engineering 11 (11-12), S. 1840-1851.
Volltext nicht vorhanden.
, Lungwitz, Uta, Liebl, Renate, Fontanari, Claudia, Klar, Juergen, Kurtz, Armin, Blunk, Torsten und Goepferich, Achim
(2005)
Gene delivery with low molecular weight linear polyethylenimines.
The Journal of Gene Medicine 7 (10), S. 1287-1298.
Volltext nicht vorhanden.
, Bauer-Kreisel, Petra, Lieb, Esther, Hacker, Michael
, Tessmar, Joerg
, Schulz, Michaela B., Goepferich, Achim
und Blunk, Torsten
(2004)
Basic fibroblast growth factor enhances PPARγ ligand‐induced adipogenesis of mesenchymal stem cells.
FEBS Letters 577 (1-2), S. 277-283.
Volltext nicht vorhanden.
, Lungwitz, Uta, Klar, Juergen, Kurtz, Armin, Blunk, Torsten und Goepferich, Achim
(2004)
Polyplexes of Polyethylenimine and per-N-methylated Polyethylenimine-Cytotoxicity and Transfection Efficiency.
Journal of Nanoscience and Nanotechnology 4 (5), S. 512-520.
Volltext nicht vorhanden.
, Spruss, Thilo, Bernhardt, Günther, Buschauer, Armin und Goepferich, Achim
(2001)
Programmable biodegradable implants.
Journal of Controlled Release 73 (1), S. 75-88.
Volltext nicht vorhanden.
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