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Artikel

Ousingsawat, Jiraporn

, Schreiber, Rainer

und Kunzelmann, Karl

(2024) Functional Interdependence of Anoctamins May Influence Conclusions from Overexpression Studies. International Journal of Molecular Sciences 25 (18), S. 9998.

Kunzelmann, Karl

, Ousingsawat, Jiraporn

und Schreiber, Rainer

(2024) Anoctamins in epithelial transport. Cell Calcium 120, S. 102888.

Schreiber, Rainer, Ousingsawat, Jiraporn und Kunzelmann, Karl (2024) Epithelial Anoctamins. Cell Calcium 120, S. 102885.

Ousingsawat, Jiraporn

, Centeio, Raquel, Reyne, Nicole, McCarron, Alexandra, Cmielewski, Patricia, Schreiber, Rainer

, diStefano, Gabriella, Römermann, Dorothee, Seidler, Ursula, Donnelley, Martin und Kunzelmann, Karl

(2024) Inhibition of mucus secretion by niclosamide and benzbromarone in airways and intestine. Scientific Reports 14 (1).

Ousingsawat, Jiraporn

, Centeio, Raquel, Schreiber, Rainer

und Kunzelmann, Karl

(2023) Niclosamide, but not ivermectin, inhibits anoctamin 1 and 6 and attenuates inflammation of the respiratory tract. Pflügers Archiv - European Journal of Physiology 476, S. 211-227.

Kunzelmann, Karl

, Ousingsawat, Jiraporn

, Kraus, Andre, Park, Julien H., Marquardt, Thorsten, Schreiber, Rainer

und Buchholz, Björn (2023) Pathogenic Relationships in Cystic Fibrosis and Renal Diseases: CFTR, SLC26A9 and Anoctamins. International Journal of Molecular Sciences 24 (17), S. 13278.

Talbi, Khaoula, Ousingsawat, Jiraporn

, Centeio, Raquel, Schreiber, Rainer

und Kunzelmann, Karl

(2023) KCNE1 does not shift TMEM16A from a Ca2+ dependent to a voltage dependent Cl- channel and is not expressed in renal proximal tubule. Pflügers Archiv - European Journal of Physiology 475, S. 995-1007.

Centeio, Raquel, Cabrita, Inês

, Schreiber, Rainer

und Kunzelmann, Karl

(2023) TMEM16A/F support exocytosis but do not inhibit Notch-mediated goblet cell metaplasia of BCi-NS1.1 human airway epithelium. Frontiers in Physiology 14.

Schreiber, Rainer, Talbi, Khaoula, Ousingsawat, Jiraporn

und Kunzelmann, Karl

(2022) A TMEM16J variant leads to dysregulated cytosolic calcium which may lead to renal disease. The FASEB Journal 37 (1), e22683.

Jo, Sungwoo, Centeio, Raquel, Park, Jinhong, Ousingsawat, Jiraporn, Jeon, Dong‐kyu, Talbi, Khaoula, Schreiber, Rainer, Ryu, Kunhi, Kahlenberg, Kristin, Somoza, Veronika

, Delpiano, Livia

, Gray, Michael A., Amaral, Margarida D.

, Railean, Violeta, Beekman, Jeffrey M., Rodenburg, Lisa W., Namkung, Wan und Kunzelmann, Karl (2022) The SLC26A9 inhibitor S9‐A13 provides no evidence for a role of SLC26A9 in airway chloride secretion but suggests a contribution to regulation of ASL pH and gastric proton secretion. The FASEB Journal 36 (11), e22534.

Schreiber, Rainer

, Cabrita, Ines und Kunzelmann, Karl

(2022) Paneth Cell Secretion in vivo Requires Expression of Tmem16a and Tmem16f. Gastro Hep Advances 1 (6), S. 1088-1098.

Ousingsawat, Jiraporn

, Centeio, Raquel, Schreiber, Rainer

und Kunzelmann, Karl

(2022) Expression of SLC26A9 in Airways and Its Potential Role in Asthma. International Journal of Molecular Sciences 23 (6), S. 2998.

Ousingsawat, Jiraporn

, Centeio, Raquel, Cabrita, Inês

, Talbi, Khaoula, Zimmer, Oliver

, Graf, Moritz, Göpferich, Achim

, Schreiber, Rainer

und Kunzelmann, Karl

(2022) Airway Delivery of Hydrogel-Encapsulated Niclosamide for the Treatment of Inflammatory Airway Disease. International Journal of Molecular Sciences 23 (3), S. 1085.

Rodenburg, Lisa W., Delpiano, Livia

, Railean, Violeta, Centeio, Raquel, Pinto, Madalena C., Smits, Shannon M. A., van der Windt, Isabelle S., van Hugten, Casper F. J., van Beuningen, Sam F. B.

, Rodenburg, Remco N. P., van der Ent, Cornelis K., Amaral, Margarida D.

, Kunzelmann, Karl, Gray, Michael A., Beekman, Jeffrey M. und Amatngalim, Gimano D.

(2022) Drug Repurposing for Cystic Fibrosis: Identification of Drugs That Induce CFTR-Independent Fluid Secretion in Nasal Organoids. International Journal of Molecular Sciences 23 (20), S. 12657. Volltext nicht vorhanden.

Leitzke, Sinje, Seidel, Jana, Ahrens, Björn, Schreiber, Rainer, Kunzelmann, Karl, Sperrhacke, Maria, Bhakdi, Sucharit und Reiss, Karina (2022) Influence of Anoctamin-4 and -9 on ADAM10 and ADAM17 Sheddase Function. Membranes 12 (2), S. 123. Volltext nicht vorhanden.

Pinto, Madalena C.

, Botelho, Hugo M.

, Silva, Iris A.L.

, Railean, Violeta, Neumann, Beate

, Pepperkok, Rainer, Schreiber, Rainer, Kunzelmann, Karl und Amaral, Margarida D.

(2022) Systems Approaches to Unravel Molecular Function: High-content siRNA Screen Identifies TMEM16A Traffic Regulators as Potential Drug Targets for Cystic Fibrosis. Journal of Molecular Biology 434 (5), S. 167436. Volltext nicht vorhanden.

Talbi, Khaoula, Ousingsawat, Jiraporn, Centeio, Raquel, Schreiber, Rainer

und Kunzelmann, Karl

(2021) Calmodulin-Dependent Regulation of Overexpressed but Not Endogenous TMEM16A Expressed in Airway Epithelial Cells. Membranes 11 (9), S. 1-14.

Talbi, Khaoula, Cabrita, Inês, Kraus, Andre, Hofmann, Sascha, Skoczynski, Kathrin, Kunzelmann, Karl

, Buchholz, Bjoern und Schreiber, Rainer

(2021) The chloride channel CFTR is not required for cyst growth in an ADPKD mouse model. The FASEB Journal 35 (10), S. 1-12.

Kunzelmann, Karl

, Centeio, Raquel, Ousingsawat, Jiraporn

, Cabrita, Inês

, Schreiber, Rainer

, Talbi, Khaoula, Benedetto, Roberta, Doušová, Tereza

, Verbeken, Eric K., De Boeck, Kris und Cohen, Isaac (2021) Mucus Release and Airway Constriction by TMEM16A May Worsen Pathology in Inflammatory Lung Disease. International Journal of Molecular Sciences 22 (7852), S. 1-18.

Kunzelmann, Karl

, Talbi, Khaoula, Cabrita, Ines

und Schreiber, Rainer

(2021) Gender-Dependent Phenotype in Polycystic Kidney Disease Is Determined by Differential Intracellular Ca2+ Signals. International Journal of Molecular Sciences 2021 (22), S. 6019. (Eingereicht)

Kunzelmann, Karl, Centeio, Raquel, Ousingsawat, Jiraporn

und Schreiber, Rainer

(2021) CLCA1 Regulates Airway Mucus Production and Ion Secretion Through TMEM16A. International Journal of Molecular Sciences 2021 (22), S. 5133. (Eingereicht)

Grosch, Melanie, Brunner, Katrin, Ilyaskin, Alexandr V.

, Schober, Michael, Staudner, Tobias, Schmied, Denise, Stumpp, Tina, Schmidt, Kerstin N., Madej, M. Gregor

, Pessoa, Thaissa D., Othmen, Helga, Kubitza, Marion, Osten, Larissa, de Vries, Uwe, Mair, Magdalena M.

, Somlo, Stefan, Moser, Markus, Kunzelmann, Karl, Ziegler, Christine

, Haerteis, Silke, Korbmacher, Christoph und Witzgall, Ralph (2021) A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts. Journal of Cell Science 134 (16). Volltext nicht vorhanden.

Pereira, Catarina

, Mazein, Alexander, Farinha, Carlos M., Gray, Michael A., Kunzelmann, Karl, Ostaszewski, Marek, Balaur, Irina, Amaral, Margarida D.

und Falcao, Andre O. (2021) CyFi-MAP: an interactive pathway-based resource for cystic fibrosis. Scientific Reports 11 (1). Volltext nicht vorhanden.

Cabrita, Ines, Talbi, Khaoula, Kunzelmann, Karl und Schreiber, Rainer (2021) Loss of PKD1 and PKD2 share common effects on intracellular Ca2+ signaling. Cell Calcium 97, S. 102413. Volltext nicht vorhanden.

Cabrita, Inês, Benedetto, Roberta, Wanitchakool, Podchanart, Lerias, Joana, Centeio, Raquel, Ousingsawat, Jiraporn, Schreiber, Rainer und Kunzelmann, Karl (2021) TMEM16A Mediates Mucus Production in Human Airway Epithelial Cells. American Journal of Respiratory Cell and Molecular Biology 64 (1), S. 50-58. Volltext nicht vorhanden.

Berg, Peder

, Svendsen, Samuel L., Sorensen, Mads Vaarby

, Schreiber, Rainer, Kunzelmann, Karl

und Leipziger, Jens

(2021) The molecular mechanism of CFTR‐ and secretin‐dependent renal bicarbonate excretion. The Journal of Physiology 599 (12), S. 3003-3011. Volltext nicht vorhanden.

Centeio, Raquel, Ousingsawat, Jiraporn

, Schreiber, Rainer

und Kunzelmann, Karl

(2020) Ca2+ Dependence of Volume-Regulated VRAC/LRRC8 and TMEM16A Cl– Channels. Frontiers in Cell and Developmental Biology 8 (596879), S. 1-14.

Cabrita, Ines, Kraus, Andre, Scholz, Julia Katharina, Skoczynski, Kathrin, Schreiber, Rainer, Kunzelmann, Karl

und Buchholz, Björn (2020) Cyst growth in ADPKD is prevented by pharmacological and genetic inhibition of TMEM16A in vivo. Nature Communications 11, S. 4320.

Oliver, Paula M., Neubert, Patrick, Homann, Arne, Wendelborn, David, Bär, Anna-Lorena

, Krampert, Luka

, Trum, Maximilian, Schröder, Agnes, Ebner, Stefan, Weichselbaum, Andrea, Schatz, Valentin, Linz, Peter, Veelken, Roland, Schulte-Schrepping, Jonas

, Aschenbrenner, Anna C., Quast, Thomas, Kurts, Christian, Geisberger, Sabrina, Kunzelmann, Karl, Hammer, Karin, Binger, Katrina J., Titze, Jens, Müller, Dominik N., Kolanus, Waldemar

, Schultze, Joachim L., Wagner, Stefan und Jantsch, Jonathan

(2020) NCX1 represents an ionic Na+ sensing mechanism in macrophages. PLOS Biology 18 (6), e3000722.

Schreiber, Rainer, Ousingsawat, Jiraporn

und Kunzelmann, Karl

(2020) Targeting of Intracellular TMEM16 Proteins to the Plasma Membrane and Activation by Purinergic Signaling. International Journal of Molecular Sciences 21 (11), S. 4065.

Pinto, Madalena C.

, Schreiber, Rainer, Lerias, Joana, Ousingsawat, Jiraporn, Duarte, Aires, Amaral, Margarida

und Kunzelmann, Karl

(2020) Regulation of TMEM16A by CK2 and Its Role in Cellular Proliferation. Cells 9 (5), S. 1138.

Centeio, Raquel, Cabrita, Inês, Benedetto, Roberta, Talbi, Khaoula, Ousingsawat, Jiraporn, Schreiber, Rainer, Sullivan, John K.

und Kunzelmann, Karl

(2020) Pharmacological Inhibition and Activation of the Ca2+ Activated Cl− Channel TMEM16A. International Journal of Molecular Sciences 21 (7), S. 2557.

Silva, Iris A. L., Duarte, Aires, Marson, Fernando A. L.

, Centeio, Raquel, Doušová, Tereza, Kunzelmann, Karl und Amaral, Margarida D. (2020) Assessment of Distinct Electrophysiological Parameters in Rectal Biopsies for the Choice of the Best Diagnosis/Prognosis Biomarkers for Cystic Fibrosis. Frontiers in Physiology 11. Volltext nicht vorhanden.

Ormel, Lasse, Lauritzen, Knut H., Schreiber, Rainer, Kunzelmann, Karl und Gundersen, Vidar (2020) GABA, but Not Bestrophin-1, Is Localized in Astroglial Processes in the Mouse Hippocampus and the Cerebellum. Frontiers in Molecular Neuroscience 13. Volltext nicht vorhanden.

Berg, Peder, Svendsen, Samuel L., Sorensen, Mads V.

, Larsen, Casper K., Andersen, Jesper Frank, Jensen-Fangel, Søren, Jeppesen, Majbritt, Schreiber, Rainer, Cabrita, Ines, Kunzelmann, Karl und Leipziger, Jens (2020) Impaired Renal HCO3- Excretion in Cystic Fibrosis. Journal of the American Society of Nephrology 31 (8), S. 1711-1727. Volltext nicht vorhanden.

Sousa, Luis

, Pankonien, Ines

, Clarke, Luka A.

, Silva, Iris

, Kunzelmann, Karl

und Amaral, Margarida D.

(2020) KLF4 Acts as a wt-CFTR Suppressor through an AKT-Mediated Pathway. Cells 9 (7), S. 1607. Volltext nicht vorhanden.

Silva, Iris A.L., Doušová, Tereza, Ramalho, Sofia, Centeio, Raquel, Clarke, Luka A.

, Railean, Violeta, Botelho, Hugo M., Holubová, Andrea, Valášková, Iveta, Yeh, Jiunn-Tyng, Hwang, Tzyh-Chang, Farinha, Carlos M., Kunzelmann, Karl und Amaral, Margarida D.

(2020) Organoids as a personalized medicine tool for ultra-rare mutations in cystic fibrosis: The case of S955P and 1717-2A>G. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1866 (11), S. 165905. Volltext nicht vorhanden.

Park, Julien H, Ousingsawat, Jiraporn, Cabrita, Inês, Bettels, Ruth E, Große-Onnebrink, Jörg, Schmalstieg, Christian, Biskup, Saskia, Reunert, Janine, Rust, Stephan, Schreiber, Rainer, Kunzelmann, Karl und Marquardt, Thorsten (2020) TMEM16A deficiency: a potentially fatal neonatal disease resulting from impaired chloride currents. Journal of Medical Genetics 58 (4), S. 247-253. Volltext nicht vorhanden.

Kunzelmann, Karl

, Cabrita, Ines, Buchholz, Björn und Schreiber, Rainer

(2020) TMEM16A drives renal cyst growth by augmenting Ca2+ signaling in M1 cells. Journal of Molecular Medicine 98, S. 659-671.

Benedetto, Roberta, Centeio, Raquel, Ousingsawat, Jiraporn, Schreiber, Rainer, Kunzelmann, Karl und make_name_string expected hash reference

(2020) Transport properties in CFTR−/− knockout piglets suggest normal airway surface liquid pH and enhanced amiloride-sensitive Na+ absorption. Pflügers Archiv - European Journal of Physiology 472, S. 1507-1519.

Kunzelmann, Karl

, Centeio, Raquel, Wanitchakool, Podchanart, Cabrita, Inês, Benedetto, Roberta, Saha, Tultul, Hoque, Kazi Mirajul und Schreiber, Rainer

(2019) Control of Ion Transport by Tmem16a Expressed in Murine Intestine. Frontiers in Physiology 10 (1262), S. 1-10.

Kunzelmann, Karl

, Ousingsawat, Jiraporn

, Benedetto, Roberta, Cabrita, Ines und Schreiber, Rainer

(2019) Contribution of Anoctamins to Cell Survival and Cell Death. Cancers 11 (3), S. 382.

Kunzelmann, Karl

, Ousingsawat, Jiraporn

, Cabrita, Inês, Doušová, Tereza, Bähr, Andrea, Janda, Melanie, Schreiber, Rainer

und Benedetto, Roberta (2019) TMEM16A in Cystic Fibrosis: Activating or Inhibiting? Frontiers in Pharmacology 10 (3), S. 1-18.

Bleibaum, Florian

, Sommer, Anselm, Veit, Martin, Rabe, Björn, Andrä, Jörg, Kunzelmann, Karl, Nehls, Christian, Correa, Wilmar, Gutsmann, Thomas, Grötzinger, Joachim, Bhakdi, Sucharit, Reiss, Karina und Fu, Haian (2019) ADAM10 sheddase activation is controlled by cell membrane asymmetry. Journal of Molecular Cell Biology 11 (11), S. 979-993. Volltext nicht vorhanden.

Nagy, Magdolna, van Geffen, Johanna P., Stegner, David

, Adams, David J., Braun, Attila, de Witt, Susanne M., Elvers, Margitta, Geer, Mitchell J.

, Kuijpers, Marijke J. E., Kunzelmann, Karl, Mori, Jun, Oury, Cécile, Pircher, Joachim, Pleines, Irina, Poole, Alastair W., Senis, Yotis A., Verdoold, Remco, Weber, Christian

, Nieswandt, Bernhard, Heemskerk, Johan W. M. und Baaten, Constance C. F. M. J. (2019) Comparative Analysis of Microfluidics Thrombus Formation in Multiple Genetically Modified Mice: Link to Thrombosis and Hemostasis. Frontiers in Cardiovascular Medicine 6. Volltext nicht vorhanden.

Miner, Kent, Labitzke, Katja, Liu, Benxian, Wang, Paul, Henckels, Kathryn, Gaida, Kevin, Elliott, Robin, Chen, Jian Jeffrey, Liu, Longbin, Leith, Anh, Trueblood, Esther, Hensley, Kelly, Xia, Xing-Zhong, Homann, Oliver, Bennett, Brian, Fiorino, Mike, Whoriskey, John, Yu, Gang, Escobar, Sabine, Wong, Min, Born, Teresa L., Budelsky, Alison, Comeau, Mike, Smith, Dirk, Phillips, Jonathan

, Johnston, James A., McGivern, Joseph G., Weikl, Kerstin, Powers, David, Kunzelmann, Karl, Mohn, Deanna, Hochheimer, Andreas und Sullivan, John K. (2019) Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide Are Potent TMEM16A Antagonists That Fully Bronchodilate Airways. Frontiers in Pharmacology 10. Volltext nicht vorhanden.

Schreiber, Rainer, Buchholz, Björn, Kraus, Andre, Schley, Gunnar, Scholz, Julia, Ousingsawat, Jiraporn und Kunzelmann, Karl (2019) Lipid Peroxidation Drives Renal Cyst Growth In Vitro through Activation of TMEM16A. Journal of the American Society of Nephrology 30 (2), S. 228-242. Volltext nicht vorhanden.

Cabrita, Inês, Benedetto, Roberta, Schreiber, Rainer und Kunzelmann, Karl

(2019) Niclosamide repurposed for the treatment of inflammatory airway disease. JCI Insight 4 (15). Volltext nicht vorhanden.

Benedetto, Roberta, Ousingsawat, Jiraporn, Cabrita, Inês, Pinto, Madalena, Lérias, Joana R., Wanitchakool, Podchanart, Schreiber, Rainer und Kunzelmann, Karl

(2019) Plasma membrane–localized TMEM16 proteins are indispensable for expression of CFTR. Journal of Molecular Medicine 97 (5), S. 711-722. Volltext nicht vorhanden.

Benedetto, Roberta, Cabrita, Inês, Schreiber, Rainer und Kunzelmann, Karl (2019) TMEM16A is indispensable for basal mucus secretion in airways and intestine. The FASEB Journal 33 (3), S. 4502-4512. Volltext nicht vorhanden.

Ousingsawat, Jiraporn, Schreiber, Rainer und Kunzelmann, Karl

(2019) TMEM16F/Anoctamin 6 in Ferroptotic Cell Death. Cancers 11, S. 625.

Lérias, Joana R., Pinto, Madalena C.

, Botelho, Hugo M.

, Awatade, Nikhil T., Quaresma, Margarida C., Silva, Iris A.L.

, Wanitchakool, Podchanart, Schreiber, Rainer, Pepperkok, Rainer, Kunzelmann, Karl und Amaral, Margarida D.

(2018) A novel microscopy-based assay identifies extended synaptotagmin-1 (ESYT1) as a positive regulator of anoctamin 1 traffic. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1865 (2), S. 421-431. Volltext nicht vorhanden.

Veit, Martin, Koyro, Katharina Isabelle, Ahrens, Björn, Bleibaum, Florian, Munz, Martin, Rövekamp, Hagen, Andrä, Jörg, Schreiber, Rainer, Kunzelmann, Karl, Sommer, Anselm, Bhakdi, Sucharit und Reiss, Karina (2018) Anoctamin-6 regulates ADAM sheddase function. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1865 (11), S. 1598-1610. Volltext nicht vorhanden.

Simões, Filipa, Ousingsawat, Jiraporn, Wanitchakool, Podchanart, Fonseca, Ana

, Cabrita, Inês, Benedetto, Roberta, Schreiber, Rainer und Kunzelmann, Karl (2018) CFTR supports cell death through ROS-dependent activation of TMEM16F (anoctamin 6). Pflügers Archiv - European Journal of Physiology 470 (2), S. 305-314. Volltext nicht vorhanden.

Lérias, Joana

, Pinto, Madalena

, Benedetto, Roberta, Schreiber, Rainer, Amaral, Margarida

, Aureli, Massimo

und Kunzelmann, Karl (2018) Compartmentalized crosstalk of CFTR and TMEM16A (ANO1) through EPAC1 and ADCY1. Cellular Signalling 44, S. 10-19. Volltext nicht vorhanden.

Ousingsawat, Jiraporn, Wanitchakool, Podchanart, Schreiber, Rainer und Kunzelmann, Karl (2018) Contribution of TMEM16F to pyroptotic cell death. Cell Death & Disease 9 (3). Volltext nicht vorhanden.

Kraus, Andre, Peters, Dorien J.M., Klanke, Bernd, Weidemann, Alexander, Willam, Carsten, Schley, Gunnar, Kunzelmann, Karl, Eckardt, Kai-Uwe und Buchholz, Bjoern (2018) HIF-1α promotes cyst progression in a mouse model of autosomal dominant polycystic kidney disease. Kidney International 94 (5), S. 887-899. Volltext nicht vorhanden.

Schenk, Laura K., Buchholz, Bjoern, Henke, Sebastian F., Michgehl, Ulf, Daniel, Christoph

, Amann, Kerstin, Kunzelmann, Karl und Pavenstädt, Hermann (2018) Nephron-specific knockout of TMEM16A leads to reduced number of glomeruli and albuminuria. American Journal of Physiology-Renal Physiology 315 (6), F1777-F1786. Volltext nicht vorhanden.

von Mässenhausen, Anne, Tonnus, Wulf, Himmerkus, Nina, Parmentier, Simon, Saleh, Danish, Rodriguez, Diego, Ousingsawat, Jiraporn, Ang, Rosalind L., Weinberg, Joel M., Sanz, Ana B.

, Ortiz, Alberto, Zierleyn, Adrian, Becker, Jan Ulrich, Baratte, Blandine, Desban, Nathalie, Bach, Stéphane, Schiessl, Ina Maria

, Nogusa, Shoko, Balachandran, Siddharth, Anders, Hans Joachim, Ting, Adrian T., Bleich, Markus

, Degterev, Alexei, Kunzelmann, Karl, Bornstein, Stefan R., Green, Douglas R.

, Hugo, Christian und Linkermann, Andreas (2018) Phenytoin inhibits necroptosis. Cell Death & Disease 9 (3). Volltext nicht vorhanden.

Hagmann, Henning, Mangold, Nicole, Rinschen, Markus M.

, Koenig, Tim, Kunzelmann, Karl, Schermer, Bernhard

, Benzing, Thomas und Brinkkoetter, Paul T. (2018) Proline‐dependent and basophilic kinases phosphorylate human TRPC6 at serine 14 to control channel activity through increased membrane expression. The FASEB Journal 32 (1), S. 208-219. Volltext nicht vorhanden.

Schenk, Laura K., Ousingsawat, Jiraporn, Skryabin, Boris V.

, Schreiber, Rainer, Pavenstädt, Hermann und Kunzelmann, Karl

(2018) Regulation and Function of TMEM16F in Renal Podocytes. International Journal of Molecular Sciences 19, S. 1798.

Ousingsawat, Jiraporn, Cabrita, Inês, Wanitchakool, Podchanart, Sirianant, Lalida, Krautwald, Stefan, Linkermann, Andreas

, Schreiber, Rainer und Kunzelmann, Karl (2017) Ca2+ signals, cell membrane disintegration, and activation of TMEM16F during necroptosis. Cellular and Molecular Life Sciences 74 (1), S. 173-181. Volltext nicht vorhanden.

Wanitchakool, Podchanart, Ousingsawat, Jiraporn, Sirianant, Lalida, Cabrita, Inês, Faria, Diana, Schreiber, Rainer und Kunzelmann, Karl (2017) Cellular defects by deletion of ANO10 are due to deregulated local calcium signaling. Cellular Signalling 30, S. 41-49. Volltext nicht vorhanden.

Cabrita, Inês, Benedetto, Roberta, Fonseca, Ana

, Wanitchakool, Podchanart, Sirianant, Lalida, Skryabin, Boris V., Schenk, Laura K., Pavenstädt, Hermann, Schreiber, Rainer und Kunzelmann, Karl (2017) Differential effects of anoctamins on intracellular calcium signals. The FASEB Journal 31 (5), S. 2123-2134. Volltext nicht vorhanden.

Benedetto, Roberta, Ousingsawat, Jiraporn, Wanitchakool, Podchanart, Zhang, Yong, Holtzman, Michael J., Amaral, Margarida

, Rock, Jason R., Schreiber, Rainer und Kunzelmann, Karl (2017) Epithelial Chloride Transport by CFTR Requires TMEM16A. Scientific Reports 7 (1). Volltext nicht vorhanden.

Schreiber, Rainer, Ousingsawat, Jiraporn

, Wanitchakool, Podchanart, Sirianant, Lalida, Benedetto, Roberta, Reiss, Karina und Kunzelmann, Karl

(2017) Regulation of TMEM16A/ANO1 and TMEM16F/ANO6 ion currents and phospholipid scrambling by Ca2+and plasma membrane lipid. The Journal of Physiology 596 (2), S. 217-229. Volltext nicht vorhanden.

Sirianant, Lalida, Ousingsawat, Jiraporn, Wanitchakool, Podchanart, Schreiber, Rainer und Kunzelmann, Karl (2016) Cellular volume regulation by anoctamin 6: Ca2+, phospholipase A2 and osmosensing. Pflügers Archiv - European Journal of Physiology 468 (2), S. 335-349. Volltext nicht vorhanden.

Wanitchakool, Podchanart, Ousingsawat, Jiraporn, Sirianant, Lalida, MacAulay, Nanna

, Schreiber, Rainer und Kunzelmann, Karl (2016) Cl− channels in apoptosis. European Biophysics Journal 45 (7), S. 599-610. Volltext nicht vorhanden.

Schreiber, Rainer und Kunzelmann, Karl (2016) Expression of anoctamins in retinal pigment epithelium (RPE). Pflügers Archiv - European Journal of Physiology 468 (11-12), S. 1921-1929. Volltext nicht vorhanden.

Kraus, Andre, Schley, Gunnar, Kunzelmann, Karl, Schreiber, Rainer, Peters, Dorien J. M., Stadler, Ruth, Eckardt, Kai-Uwe und Buchholz, Bjoern (2016) Glucose promotes secretion-dependent renal cyst growth. Journal of Molecular Medicine 94 (1), S. 107-117. Volltext nicht vorhanden.

Sirianant, Lalida, Wanitchakool, Podchanart, Ousingsawat, Jiraporn, Benedetto, Roberta, Zormpa, Anna, Cabrita, Ines, Schreiber, Rainer und Kunzelmann, Karl (2016) Non-essential contribution of LRRC8A to volume regulation. Pflügers Archiv - European Journal of Physiology 468 (5), S. 805-816. Volltext nicht vorhanden.

Kraus, Andre, Grampp, Steffen, Goppelt-Struebe, Margarete, Schreiber, Rainer, Kunzelmann, Karl, Peters, Dorien J. M., Leipziger, Jens

, Schley, Gunnar, Schödel, Johannes, Eckardt, Kai-Uwe und Buchholz, Bjoern (2016) P2Y2R is a direct target of HIF-1α and mediates secretion-dependent cyst growth of renal cyst-forming epithelial cells. Purinergic Signalling 12 (4), S. 687-695. Volltext nicht vorhanden.

Sommer, Anselm, Kordowski, Felix, Büch, Joscha, Maretzky, Thorsten

, Evers, Astrid, Andrä, Jörg, Düsterhöft, Stefan, Michalek, Matthias, Lorenzen, Inken, Somasundaram, Prasath, Tholey, Andreas

, Sönnichsen, Frank D., Kunzelmann, Karl, Heinbockel, Lena, Nehls, Christian, Gutsmann, Thomas, Grötzinger, Joachim, Bhakdi, Sucharit und Reiss, Karina (2016) Phosphatidylserine exposure is required for ADAM17 sheddase function. Nature Communications 7 (1). Volltext nicht vorhanden.

Benedetto, Roberta, Sirianant, Lalida, Pankonien, Ines

, Wanitchakool, Podchanart, Ousingsawat, Jiraporn, Cabrita, Ines, Schreiber, Rainer, Amaral, Margarida

und Kunzelmann, Karl (2016) Relationship between TMEM16A/anoctamin 1 and LRRC8A. Pflügers Archiv - European Journal of Physiology 468 (10), S. 1751-1763. Volltext nicht vorhanden.

Mattheij, Nadine J. A., Braun, Attila, Kruchten, Roger, Castoldi, Elisabetta, Pircher, Joachim, Baaten, Constance C. F. M. J., Wülling, Manuela, Kuijpers, Marijke J. E., Köhler, Ralf, Poole, Alastair W.

, Schreiber, Rainer, Vortkamp, Andrea, Collins, Peter W., Nieswandt, Bernhard, Kunzelmann, Karl, Cosemans, Judith M. E. M und Heemskerk, Johan W. M. (2016) Survival protein anoctamin‐6 controls multiple platelet responses including phospholipid scrambling, swelling, and protein cleavage. The FASEB Journal 30 (2), S. 727-737. Volltext nicht vorhanden.

Baig, Ayesha A., Haining, Elizabeth J., Geuss, Eva, Beck, Sarah, Swieringa, Frauke, Wanitchakool, Podchanart, Schuhmann, Michael K., Stegner, David, Kunzelmann, Karl, Kleinschnitz, Christoph, Heemskerk, Johan W. M., Braun, Attila und Nieswandt, Bernhard (2016) TMEM16F-Mediated Platelet Membrane Phospholipid Scrambling Is Critical for Hemostasis and Thrombosis but not Thromboinflammation in Mice—Brief Report. Arteriosclerosis, Thrombosis, and Vascular Biology 36 (11), S. 2152-2157. Volltext nicht vorhanden.

Guoxing, Liu, Guilai, Liu, Hong, Chen, Borst, Oliver, Gawaz, Meinrad, Vortkamp, Andrea, Schreiber, Rainer

, Kunzelmann, Karl

und Lang, Florian (2015) Involvement of Ca2+ Activated Cl- Channel Ano6 in Platelet Activation and Apoptosis. Cellular Physiology and Biochemistry 37 (5), S. 1934-1944.

Szteyn, K., Schmid, Evi, Nurbaeva, M.K., Wang, Wenting, Münzer, P., Kunzelmann, Karl

, Lang, Florian und Shumilina, E. (2012) Expression and Functional Significance of the Ca2+-Activated Cl- Channel ANO6 in Dendritic Cells. Cellular Physiology and Biochemistry 30, S. 13196-1332.

Milenkovic, Vladimir M., Langmann, Thomas, Schreiber, Rainer

, Kunzelmann, Karl

und Weber, Bernhard H. F.

(2008) Molecular evolution and functional divergence of the bestrophin protein family. BMC Evolutionary Biology 8, S. 72.

Kunzelmann, Karl, Scheidt, Kerstin, Scharf, Birgit, Ousingsawat, Jiraporn, Schreiber, Rainer, Wainwright, Brandon und McMorran, Brendan (2006) Flagellin of Pseudomonas aeruginosa inhibits Na
transport in airway epithelia. The FASEB Journal 20 (3), S. 545-546. Volltext nicht vorhanden.

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