Anzahl der Einträge: 209.
2024
Gross, Simon,
Danielyan, Lusine,
Buechler, Christa ,
Kubitza, Marion,
Klein, Kathrin,
Schwab, Matthias,
Melter, Michael und
Weiss, Thomas S.
(2024)
Hepatic Amyloid Beta-42-Metabolizing Proteins in Liver Steatosis and Metabolic Dysfunction-Associated Steatohepatitis.
International Journal of Molecular Sciences 25 (16), S. 8768.
Dropmann, Anne,
Alex, Sophie,
Schorn, Katharina,
Tong, Chenhao,
Caccamo, Tiziana,
Godoy, Patricio,
Ilkavets, Iryna,
Liebe, Roman,
Gonzalez, Daniela,
Hengstler, Jan G.,
Piiper, Albrecht,
Quagliata, Luca,
Matter, Matthias S.,
Waidmann, Oliver,
Finkelmeier, Fabian,
Feng, Teng,
Weiss, Thomas S. ,
Rahbari, Nuh,
Birgin, Emrullah,
Rasbach, Erik,
Roessler, Stephanie ,
Breuhahn, Kai,
Tóth, Marcell,
Ebert, Matthias P.,
Dooley, Steven,
Hammad, Seddik und
Meindl-Beinker, Nadja M.
(2024)
The TGF-β1 target WISP1 is highly expressed in liver cirrhosis and cirrhotic HCC microenvironment and involved in pro- and anti-tumorigenic effects.
Biochemical and Biophysical Research Communications 732, S. 150409.
Buniatian, Gayane Hrachia,
Schwinghammer, Ute,
Tremmel, Roman ,
Cynis, Holger,
Weiss, Thomas S. ,
Weiskirchen, Ralf ,
Lauschke, Volker M.,
Youhanna, Sonia,
Ramos, Isbaal,
Valcarcel, Maria,
Seferyan, Torgom,
Rahfeld, Jens‐Ulrich,
Rieckmann, Vera,
Klein, Kathrin,
Buadze, Marine,
Weber, Victoria,
Kolak, Valentina,
Gebhardt, Rolf,
Friedman, Scott L. ,
Müller, Ulrike C.,
Schwab, Matthias und
Danielyan, Lusine
(2024)
Consequences of Amyloid‐β Deficiency for the Liver.
Advanced Science 11 (18).
2023
Schilcher, Katharina,
Dayoub, Rania ,
Kubitza, Marion,
Riepl, Jakob,
Klein, Kathrin,
Buechler, Christa ,
Melter, Michael und
Weiss, Thomas S.
(2023)
Saturated Fat-Mediated Upregulation of IL-32 and CCL20 in Hepatocytes Contributes to Higher Expression of These Fibrosis-Driving Molecules in MASLD.
International Journal of Molecular Sciences 24 (17), S. 13222.
Staufer, Katharina,
Huber, Heidemarie,
Zessner-Spitzenberg, Jasmin,
Stauber, Rudolf,
Finkenstedt, Armin,
Bantel, Heike,
Weiss, Thomas S. ,
Huber, Markus A. ,
Starlinger, Patrick,
Gruenberger, Thomas,
Reiberger, Thomas,
Sebens, Susanne,
McIntyre, Gail,
Tabibiazar, Ray,
Giaccia, Amato,
Zoller, Heinz,
Trauner, Michael und
Mikulits, Wolfgang
(2023)
Gas6 in chronic liver disease—a novel blood-based biomarker for liver fibrosis.
Cell Death Discovery 9, S. 282.
Nimphy, Jonas,
Ibrahim, Sara,
Dayoub, Rania ,
Kubitza, Marion,
Melter, Michael und
Weiss, Thomas S.
(2023)
Interleukin-1ß Attenuates Expression of Augmenter of Liver Regeneration (ALR) by Regulating HNF4α Independent of c-Jun.
International Journal of Molecular Sciences 24 (9), S. 8107.
2022
Pohl, Rebekka,
Eichelberger, Laura,
Feder, Susanne,
Haberl, Elisabeth M. ,
Rein-Fischboeck, Lisa,
McMullen, Nichole ,
Sinal, Christopher J.,
Bruckmann, Astrid,
Weiss, Thomas S. ,
Beck, Michael,
Höring, Marcus ,
Krautbauer, Sabrina,
Liebisch, Gerhard ,
Wiest, Reiner,
Wanninger, Josef und
Buechler, Christa
(2022)
Hepatocyte expressed chemerin-156 does not protect from experimental non-alcoholic steatohepatitis.
Molecular and Cellular Biochemistry.
Mayer, Mascha,
Berger, Alexander,
Leischner, Christian,
Renner, Olga,
Burkard, Markus,
Böcker, Alexander,
Noor, Seema,
Weiland, Timo,
Weiss, Thomas S. ,
Busch, Christian,
Lauer, Ulrich M.,
Bischoff, Stephan C. und
Venturelli, Sascha
(2022)
Preclinical Efficacy and Toxicity Analysis of the Pan-Histone Deacetylase Inhibitor Gossypol for the Therapy of Colorectal Cancer or Hepatocellular Carcinoma.
Pharmaceuticals 15 (4), S. 438.
Pohl, Rebekka,
Feder, Susanne,
Haberl, Elisabeth M. ,
Rein-Fischboeck, Lisa,
Weiss, Thomas S. ,
Spirk, Marlen,
Bruckmann, Astrid,
McMullen, Nichole ,
Sinal, Christopher J. und
Buechler, Christa
(2022)
Chemerin Overexpression in the Liver Protects against Inflammation in Experimental Non-Alcoholic Steatohepatitis.
Biomedicines 10 (1), S. 132.
2021
Haberl, Elisabeth M.,
Weiss, Thomas S. ,
Peschel, Georg,
Weigand, Kilian,
Köhler, Nikolai ,
Pauling, Josch K.,
Wenzel, Jürgen J. ,
Höring, Marcus,
Krautbauer, Sabrina,
Liebisch, Gerhard und
Buechler, Christa
(2021)
Liver Lipids of Patients with Hepatitis B and C and Associated Hepatocellular Carcinoma.
International Journal of Molecular Sciences 22 (10), S. 5297.
Feder, Susanne,
Wiest, Reiner,
Weiss, Thomas S. ,
Aslanidis, Charalampos,
Schacherer, Doris,
Krautbauer, Sabrina,
Liebisch, Gerhard und
Buechler, Christa
(2021)
Proprotein convertase subtilisin/kexin type 9 (PCSK9) levels are not associated with severity of liver disease and are inversely related to cholesterol in a cohort of thirty eight patients with liver cirrhosis.
Lipids in Health and Disease 20 (6), S. 1-14.
Gianmoena, Kathrin,
Gasparoni, Nina,
Jashari, Adelina,
Gabrys, Philipp,
Grgas, Katharina,
Ghallab, Ahmed ,
Nordström, Karl,
Gasparoni, Gilles,
Reinders, Jörg,
Edlund, Karolina,
Godoy, Patricio,
Schriewer, Alexander,
Hayen, Heiko,
Hudert, Christian A.,
Damm, Georg ,
Seehofer, Daniel,
Weiss, Thomas S. ,
Boor, Peter,
Anders, Hans-Joachim,
Motrapu, Manga ,
Jansen, Peter,
Schiergens, Tobias S.,
Falk-Paulsen, Maren,
Rosenstiel, Philip,
Lisowski, Clivia,
Salido, Eduardo,
Marchan, Rosemarie,
Walter, Jörn ,
Hengstler, Jan G. und
Cadenas, Cristina
(2021)
Epigenomic and transcriptional profiling identifies impaired glyoxylate detoxification in NAFLD as a risk factor for hyperoxaluria.
Cell Reports 36 (8), S. 109526.
Volltext nicht vorhanden.
2020
Buniatian, Gayane Hrachia,
Weiskirchen, Ralf ,
Weiss, Thomas S. ,
Schwinghammer, Ute,
Fritz, Martin,
Seferyan, Torgom,
Proksch, Barbara,
Glaser, Michael,
Lourhmati, Ali,
Buadze, Marine,
Borkham-Kamphorst, Erawan,
Gaunitz, Frank ,
Gleiter, Christoph H.,
Lang, Thomas,
Schaeffeler, Elke,
Tremmel, Roman ,
Cynis, Holger,
Frey, William H.,
Gebhardt, Rolf,
Friedman, Scott L. ,
Mikulits, Wolfgang ,
Schwab, Matthias und
Danielyan, Lusine
(2020)
Antifibrotic Effects of Amyloid-Beta and Its Loss in Cirrhotic Liver.
Cells 9 (2), S. 452.
Volltext nicht vorhanden.
Ibrahim, Sara,
Dayoub, Rania ,
Saberi, Veronika,
Buchner, Monika,
Melter, Michael und
Weiss, Thomas S.
(2020)
Augmenter of Liver Regeneration (ALR) regulates bile acid synthesis and attenuates bile acid-induced apoptosis via glycogen synthase kinase-3β (GSK-3β) inhibition.
Experimental Cell Research 397 (1), S. 112343.
Volltext nicht vorhanden.
Haberl, Elisabeth M.,
Feder, Susanne,
Pohl, Rebekka,
Rein-Fischboeck, Lisa,
Dürholz, Kerstin,
Eichelberger, Laura,
Wanninger, Josef,
Weiss, Thomas S. und
Buechler, Christa
(2020)
Chemerin Is Induced in Non-Alcoholic Fatty Liver Disease and Hepatitis B-Related Hepatocellular Carcinoma.
Cancers 12 (10), S. 2967.
Volltext nicht vorhanden.
Campos, Gisela,
Schmidt-Heck, Wolfgang,
De Smedt, Jonathan,
Widera, Agata,
Ghallab, Ahmed ,
Pütter, Larissa,
González, Daniela,
Edlund, Karolina,
Cadenas, Cristina,
Marchan, Rosemarie,
Guthke, Reinhard,
Verfaillie, Catherine,
Hetz, Claudio,
Sachinidis, Agapios,
Braeuning, Albert,
Schwarz, Michael,
Weiss, Thomas S. ,
Banhart, Benjamin K.,
Hoek, Jan,
Vadigepalli, Rajanikanth,
Willy, Jeffrey,
Stevens, James L.,
Hay, David C.,
Hengstler, Jan G. und
Godoy, Patricio
(2020)
Inflammation-associated suppression of metabolic gene networks in acute and chronic liver disease.
Archives of Toxicology 94 (1), S. 205-217.
Volltext nicht vorhanden.
Feder, Susanne,
Haberl, Elisabeth M.,
Spirk, Marlen,
Weiss, Thomas S. ,
Wiest, Reiner und
Büchler, Christa
(2020)
Pentraxin-3 is not related to disease severity in cirrhosis and hepatocellular carcinoma patients.
Clinical and Experimental Medicine 20, S. 289-297.
Dropmann, Anne,
Dooley, Steven,
Dewidar, Bedair,
Hammad, Seddik,
Dediulia, Tatjana,
Werle, Julia,
Hartwig, Vanessa,
Ghafoory, Shahrouz,
Woelfl, Stefan,
Korhonen, Hanna,
Janicot, Michel,
Wosikowski, Katja,
Itzel, Timo,
Teufel, Andreas,
Schuppan, Detlef,
Stojanovic, Ana ,
Cerwenka, Adelheid,
Nittka, Stefanie,
Piiper, Albrecht,
Gaiser, Timo,
Beraza, Naiara ,
Milkiewicz, Malgorzata,
Milkiewicz, Piotr,
Brain, John G.,
Jones, David E. J.,
Weiss, Thomas S. ,
Zanger, Ulrich M.,
Ebert, Matthias und
Meindl-Beinker, Nadja M.
(2020)
TGF-β2 silencing to target biliary-derived liver diseases.
Gut 69 (9), S. 1677-1690.
Volltext nicht vorhanden.
2019
Weiss, Thomas S. ,
Lupke, Madeleine,
Dayoub, Rania ,
Geissler, Edward K.,
Schlitt, Hans J.,
Melter, Michael und
Eggenhofer, Elke
(2019)
Augmenter of Liver Regeneration Reduces Ischemia Reperfusion Injury by Less Chemokine Expression, Gr-1 Infiltration and Oxidative Stress.
Cells 8 (11), S. 1421.
Kaur, Savneet,
Rawal, Preety,
Siddiqui, Hamda,
Rohilla, Sumai,
Sharma, Shvetank,
Tripathi, Dinesh M.,
Baweja, Sukriti,
Hassan, Mohsin,
Vlaic, Sebastian,
Guthke, Reinhard,
Thomas, Maria,
Dayoub, Rania ,
Bihari, Chaggan,
Sarin, Shiv K. und
Weiss, Thomas S.
(2019)
Increased Expression of RUNX1 in Liver Correlates with NASH Activity Score in Patients with Non-Alcoholic Steatohepatitis (NASH).
Cells 8 (10), S. 1277.
Ibrahim, Sara,
Dayoub, Rania ,
Krautbauer, Sabrina,
Liebisch, Gerhard ,
Wege, Anja Kathrin ,
Melter, Michael und
Weiss, Thomas S.
(2019)
Bile acid-induced apoptosis and bile acid synthesis are reduced by over-expression of Augmenter of Liver Regeneration (ALR) in a STAT3-dependent mechanism.
Experimental Cell Research 374 (1), S. 189-197.
Volltext nicht vorhanden.
Asimakopoulou, Anastasia,
Vucur, Mihael,
Luedde, Tom,
Schneiders, Silvia,
Kalampoka, Stavroula,
Weiss, Thomas S. und
Weiskirchen, Ralf
(2019)
Perilipin 5 and Lipocalin 2 Expression in Hepatocellular Carcinoma.
Cancers 11 (3), S. 385.
Volltext nicht vorhanden.
2018
Kaur, Savneet,
Rawal, Preety Rawal,
Siddiqui, Hamda,
Rohilla, Sumati,
Sukriti, Sukriti,
Bhat, Mohsin Hasan,
Kumari, Anupama,
Sharma, Shvetank,
Bihari, Chhagan,
Sarin, Shiv Kumar und
Weiss, Thomas S.
(2018)
RUNX1 Regulates Angiogenesis and Inflammation in the Pathogenesis of Non-Alcoholic Steatohepatitis.
In: Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting, NOV 09-13, 2018, San Francisco, CA.
Volltext nicht vorhanden.
Myllys, Maiju ,
Albrecht, Ute,
Dooley, Steven,
Hammad, Seddik,
Weiss, Thomas S. ,
Jan G., H. und
Godoy, Patricio
(2018)
Role of the interleukin 15/macrophage axis in the immune response of liver fibrosis.
Journal of Hepatology 68 (1), S405.
Volltext nicht vorhanden.
Henkel, Janin,
Coleman, Charles Dominic,
Schraplau, Anne,
Jöhrens, Korinna,
Weiss, Thomas S. ,
Jonas, Wenke,
Schürmann, Annette und
Püschel, Gerhard Paul
(2018)
Augmented liver inflammation in a microsomal prostaglandin E synthase 1 (mPGES-1)-deficient diet-induced mouse NASH model.
Scientific Reports 8 (1).
Volltext nicht vorhanden.
Klag, Thomas,
Thomas, Maria,
Ehmann, Dirk,
Courth, Lioba,
Mailänder-Sanchez, Daniela,
Weiss, Thomas S. ,
Dayoub, Rania ,
Abshagen, Kerstin,
Vollmar, Brigitte,
Thasler, Wolfgang E.,
Stange, Eduard F.,
Berg, Christoph P.,
Malek, Nisar P.,
Zanger, Ulrich M. und
Wehkamp, Jan
(2018)
β-Defensin 1 Is Prominent in the Liver and Induced During Cholestasis by Bilirubin and Bile Acids via Farnesoid X Receptor and Constitutive Androstane Receptor.
Frontiers in Immunology 9.
Volltext nicht vorhanden.
2017
Weiss, Thomas S. ,
Lupke, Madeleine,
Ibrahim, Sara,
Buechler, Christa ,
Lorenz, Julia,
Ruemmele, Petra,
Hofmann, Ute ,
Melter, Michael und
Dayoub, Rania
(2017)
Attenuated lipotoxicity and apoptosis is linked to exogenous and endogenous augmenter of liver regeneration by different pathways.
PLOS ONE 12 (9), e0184282.
Krautbauer, Sabrina,
Weiss, Thomas S. ,
Wiest, Reiner ,
Schacherer, Doris,
Liebisch, Gerhard und
Buechler, Christa
(2017)
Diagnostic Value of Systemic Cholesteryl Ester/Free Cholesterol Ratio in Hepatocellular Carcinoma.
Anticancer Research 37 (7), S. 3527-3535.
Volltext nicht vorhanden.
Dengler, M.,
Staufer, K.,
Huber, H.,
Stauber, R.,
Bantel, H.,
Weiss, K.H.,
Starlinger, P.,
Pock, H.,
Klöters-Plachky, P.,
Gotthardt, D.N.,
Rauch, P.,
Lackner, C.,
Stift, J.,
Brostjan, C.,
Gruenberger, T.,
Kumada, T.,
Toyoda, H.,
Tada, T.,
Weiss, Thomas S. ,
Trauner, M. und
Mikulits, W.
(2017)
Soluble Axl identifies patients at higher risk for hepatocellular carcinoma development: results from a large scale multicenter analysis.
Journal of Hepatology 66 (1), S626.
Volltext nicht vorhanden.
Zimny, Sebastian,
Pohl, Rebekka,
Rein-Fischboeck, Lisa,
Haberl, Elisabeth M. ,
Krautbauer, Sabrina,
Weiss, Thomas S. und
Buechler, Christa
(2017)
Chemokine (CC-motif) receptor-like 2 mRNA is expressed in hepatic stellate cells and is positively associated with characteristics of non-alcoholic steatohepatitis in mice and men.
Experimental and Molecular Pathology 103 (1), S. 1-8.
Volltext nicht vorhanden.
Jeske, Judith,
Bitter, Andreas,
Thasler, Wolfgang E.,
Weiss, Thomas S. ,
Schwab, Matthias und
Burk, Oliver
(2017)
Ligand-dependent and -independent regulation of human hepatic sphingomyelin phosphodiesterase acid-like 3A expression by pregnane X receptor and crosstalk with liver X receptor.
Biochemical Pharmacology 136, S. 122-135.
Volltext nicht vorhanden.
Dengler, Mirko,
Staufer, Katharina,
Huber, Heidemarie,
Stauber, Rudolf,
Bantel, Heike,
Weiss, Karl Heinz,
Starlinger, Patrick,
Pock, Hannelore,
Klöters-Plachky, Petra,
Gotthardt, Daniel N.,
Rauch, Peter,
Lackner, Carolin,
Stift, Judith ,
Brostjan, Christine,
Gruenberger, Thomas,
Kumada, Takashi,
Toyoda, Hidenori,
Tada, Toshifumi,
Weiss, Thomas S. ,
Trauner, Michael und
Mikulits, Wolfgang
(2017)
Soluble Axl is an accurate biomarker of cirrhosis and hepatocellular carcinoma development: results from a large scale multicenter analysis.
Oncotarget 8 (28).
Volltext nicht vorhanden.
Rein-Fischboeck, Lisa,
Pohl, Rebekka,
Haberl, Elisabeth M.,
Zimny, Sebastian,
Neumann, Maximilian,
Eisinger, Kristina,
Weiss, Thomas S. ,
Krautbauer, Sabrina und
Buechler, Christa
(2017)
Tubulin alpha 8 is expressed in hepatic stellate cells and is induced in transformed hepatocytes.
Molecular and Cellular Biochemistry 428 (1-2), S. 161-170.
Volltext nicht vorhanden.
2016
Kaur, Savneet,
Hasan, Mohsin,
Siddiqui, Hamda,
Thomas, Maria,
Dayoub, Rania ,
Sharma, Shvetank,
Sarin, Shiv Kumar und
Weiss, Thomas S.
(2016)
Angiogenesis in the Pathogenesis of Non-Alcoholic Fatty Liver Diseases (NAFLD).
In: 67th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), NOV 11-15, 2016, Boston, MA.
Volltext nicht vorhanden.
Büchler, Christa,
Neumann, Maximilian,
Meier, Elisabeth M.,
Rein-Fischboeck, Lisa,
Krautbauer, Sabrina,
Eisinger, Kristina,
Aslanidis, Charalampos,
Pohl, Rebekka und
Weiss, Thomas S.
(2016)
Chemokine-like receptor 1 mRNA weakly correlates with non-alcoholic steatohepatitis score in male but not female individuals.
International Journal of Molecular Science 17 (8), S. 1335.
Chen, Simeng,
Feng, Teng,
Vujić Spasić, Maja,
Altamura, Sandro,
Breitkopf-Heinlein, Katja,
Altenöder, Jutta,
Weiss, Thomas S. ,
Dooley, Steven und
Muckenthaler, Martina U.
(2016)
Transforming Growth Factor β1 (TGF-β1) Activates Hepcidin mRNA Expression in Hepatocytes.
Journal of Biological Chemistry 291 (25), S. 13160-13174.
Meier, Elisabeth M.,
Rein-Fischboeck, Lisa,
Pohl, Rebekka,
Wanninger, Josef,
Hoy, Andrew J. ,
Grewal, Thomas ,
Eisinger, Kristina,
Krautbauer, Sabrina,
Liebisch, Gerhard ,
Weiss, Thomas S. und
Buechler, Christa
(2016)
Annexin A6 protein is downregulated in human hepatocellular carcinoma.
Molecular and Cellular Biochemistry 418 (1-2), S. 81-90.
Volltext nicht vorhanden.
Krautbauer, Sabrina,
Meier, Elisabeth M.,
Rein-Fischboeck, Lisa,
Pohl, Rebekka ,
Weiss, Thomas S. ,
Sigruener, Alexander,
Aslanidis, Charalampos,
Liebisch, Gerhard und
Buechler, Christa
(2016)
Ceramide and polyunsaturated phospholipids are strongly reduced in human hepatocellular carcinoma.
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1861 (11), S. 1767-1774.
Volltext nicht vorhanden.
Godoy, Patricio,
Schmidt-Heck, Wolfgang,
Natarajan, Karthick,
Lucendo-Villarin, Baltasar,
Szkolnicka, Dagmara,
Asplund, Annika,
Björquist, Petter,
Widera, Agata,
Stöber, Regina,
Campos, Gisela,
Hammad, Seddik,
Sachinidis, Agapios,
Chaudhari, Umesh,
Damm, Georg,
Weiss, Thomas S. ,
Nüssler, Andreas,
Synnergren, Jane,
Edlund, Karolina,
Küppers-Munther, Barbara,
Hay, David C. und
Hengstler, Jan G.
(2016)
Corrigendum to “Gene networks and transcription factor motifs defining the differentiation of human stem cells into hepatocyte-like cells” [J Hepatol 2015;63:934–942].
Journal of Hepatology 64 (2), S. 525-526.
Volltext nicht vorhanden.
Kaur, S.,
Bhat, M.H.,
Siddiqui, H.,
Thomas, M.,
Dayoub, Rania ,
Sarin, S.K. und
Weiss, Thomas S.
(2016)
Exploring Novel Links between Angiogenesis and Lipid Metabolism in Non-Alcoholic Fatty Liver Diseases.
Journal of Hepatology 64 (2), S678-S679.
Volltext nicht vorhanden.
Godoy, Patricio,
Widera, Agata,
Schmidt-Heck, Wolfgang,
Campos, Gisela,
Meyer, Christoph,
Cadenas, Cristina,
Reif, Raymond,
Stöber, Regina,
Hammad, Seddik,
Pütter, Larissa,
Gianmoena, Kathrin,
Marchan, Rosemarie ,
Ghallab, Ahmed ,
Edlund, Karolina,
Nüssler, Andreas,
Thasler, Wolfgang E.,
Damm, Georg,
Seehofer, Daniel,
Weiss, Thomas S. ,
Dirsch, Olaf,
Dahmen, Uta,
Gebhardt, Rolf,
Chaudhari, Umesh,
Meganathan, Kesavan,
Sachinidis, Agapios,
Kelm, Jens,
Hofmann, Ute ,
Zahedi, René P. ,
Guthke, Reinhard,
Blüthgen, Nils,
Dooley, Steven und
Hengstler, Jan G.
(2016)
Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue.
Archives of Toxicology 90 (10), S. 2513-2529.
Volltext nicht vorhanden.
Matz-Soja, Madlen,
Rennert, Christiane ,
Schönefeld, Kristin,
Aleithe, Susanne,
Boettger, Jan,
Schmidt-Heck, Wolfgang,
Weiss, Thomas S. ,
Hovhannisyan, Amalya,
Zellmer, Sebastian,
Klöting, Nora,
Schulz, Angela,
Kratzsch, Jürgen,
Guthke, Reinhardt und
Gebhardt, Rolf
(2016)
Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis.
eLife 5.
Volltext nicht vorhanden.
Pohl, Rebekka,
Haberl, Elisabeth M. ,
Rein-Fischboeck, Lisa,
Zimny, Sebastian,
Neumann, Maximilian,
Aslanidis, Charalampos,
Schacherer, Doris,
Krautbauer, Sabrina,
Eisinger, Kristina,
Weiss, Thomas S. und
Buechler, Christa
(2016)
Hepatic chemerin mRNA expression is reduced in human nonalcoholic steatohepatitis.
European Journal of Clinical Investigation 47 (1), S. 7-18.
Volltext nicht vorhanden.
Chen, Simeng,
Feng, Teng,
Vujić Spasić, Maja,
Altamura, Sandro,
Breitkopf-Heinlein, Katja,
Altenöder, Jutta,
Weiss, Thomas S. ,
Dooley, Steven und
Muckenthaler, Martina U.
(2016)
Transforming Growth Factor β1 (TGF-β1) Activates Hepcidin mRNA Expression in Hepatocytes.
Journal of Biological Chemistry 291 (25), S. 13160-13174.
Volltext nicht vorhanden.
2015
Rein-Fischboeck, Lisa,
Krautbauer, Sabrina,
Eisinger, Kristina,
Pohl, Rebekka,
Meier, Elisabeth M.,
Weiss, Thomas S. und
Buechler, Christa
(2015)
Hepatic scavenger receptor BI is associated with type 2 diabetes but unrelated to human and murine non-alcoholic fatty liver disease.
Biochemical and Biophysical Research Communications 467 (2), S. 377-382.
Volltext nicht vorhanden.
Braeuning, Albert,
Thomas, Maria,
Hofmann, Ute,
Vetter, Silvia,
Zeller, Eva,
Petzuch, Barbara,
Johänning, Janina,
Schroth, Werner,
Weiss, Thomas S. ,
Zanger, Ulrich M. und
Schwarz, Michael
(2015)
Comparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor Agonists.
Drug Metabolism and Disposition 43 (11), S. 1781-1787.
Volltext nicht vorhanden.
Kaur, Savneet,
Vlaic, Sebastian,
Guthke, Reinhard,
Dayoub, Rania ,
Hasan, Mohsin,
Siddiqui, Hamda,
Weiss, Thomas S. und
Sarin, Shiv Kumar
(2015)
Angiogenesis in the pathogenesis of non-alcoholic fatty liver disease: a differential gene expression study.
In: 66th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), NOV 13-17, 2015, San Francisco, CA.
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Godoy, Patricio,
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Szkolnicka, Dagmara,
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Widera, Agata,
Stöber, Regina,
Campos, Gisela,
Hammad, Seddik,
Sachinidis, Agapios,
Chaudhari, Umesh,
Damm, Georg,
Weiss, Thomas S. ,
Nüssler, Andreas,
Synnergren, Jane,
Edlund, Karolina,
Küppers-Munther, Barbara,
Hay, David C. und
Hengstler, Jan G.
(2015)
Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells.
Journal of Hepatology 63 (4), S. 934-942.
Thomas, Maria,
Bayha, Christine,
Klein, Kathrin,
Müller, Simon,
Weiss, Thomas S. ,
Schwab, Matthias und
Zanger, Ulrich M.
(2015)
The truncated splice variant of peroxisome proliferator-activated receptor alpha, PPARα-tr, autonomously regulates proliferative and pro-inflammatory genes.
BMC Cancer 15, S. 488.
Feng, Teng,
Dzieran, Johanna,
Gu, Xing,
Marhenke, Silke,
Vogel, Arndt,
Machida, Keigo,
Weiss, Thomas S. ,
Ruemmele, Petra,
Kollmar, Otto,
Hoffmann, Patrick,
Grässer, Friedrich,
Allgayer, Heike,
Fabian, Jasmin,
Weng, Hong Lei,
Teufel, Andreas,
Maass, Thorsten,
Meyer, Christoph,
Lehmann, Ulrich,
Zhu, Cheng,
Mertens, Peter R.,
Gao, Chun Fang,
Dooley, Steven und
Meindl-Beinker, Nadja M.
(2015)
Smad7 regulates compensatory hepatocyte proliferation in damaged mouse liver and positively relates to better clinical outcome in human hepatocellular carcinoma.
Clinical Science 128 (11), S. 761-774.
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Weiß, Frederik,
Schnabel, Anke,
Planatscher, Hannes,
van den Berg, Bart H. J.,
Serschnitzki, Bettina,
Nuessler, Andreas K.,
Thasler, Wolfgang E.,
Weiss, Thomas S. ,
Reuss, Matthias,
Stoll, Dieter,
Templin, Markus F.,
Joos, Thomas O.,
Marcus, Katrin und
Poetz, Oliver
(2015)
Indirect protein quantification of drug-transforming enzymes using peptide group-specific immunoaffinity enrichment and mass spectrometry.
Scientific Reports 5.
Schuster, Susanne,
Penke, Melanie,
Gorski, Theresa,
Gebhardt, Rolf,
Weiss, Thomas S. ,
Kiess, Wieland und
Garten, Antje
(2015)
FK866-induced NAMPT inhibition activates AMPK and downregulates mTOR signaling in hepatocarcinoma cells.
Biochemical and Biophysical Research Communications 458 (2), S. 334-340.
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2014
Grinberg, Marianna,
Stöber, Regina M.,
Edlund, Karolina,
Rempel, Eugen,
Godoy, Patricio,
Reif, Raymond,
Widera, Agata,
Madjar, Katrin,
Schmidt-Heck, Wolfgang,
Marchan, Rosemarie,
Sachinidis, Agapios,
Spitkovsky, Dimitry,
Hescheler, Jürgen,
Carmo, Helena,
Arbo, Marcelo D.,
van de Water, Bob,
Wink, Steven,
Vinken, Mathieu,
Rogiers, Vera,
Escher, Sylvia,
Hardy, Barry,
Mitic, Dragana,
Myatt, Glenn,
Waldmann, Tanja,
Mardinoglu, Adil,
Damm, Georg,
Seehofer, Daniel,
Nüssler, Andreas,
Weiss, Thomas S. ,
Oberemm, Axel,
Lampen, Alfons,
Schaap, Mirjam M.,
Luijten, Mirjam,
van Steeg, Harry,
Thasler, Wolfgang E.,
Kleinjans, Jos C. S.,
Stierum, Rob H.,
Leist, Marcel,
Rahnenführer, Jörg und
Hengstler, Jan G.
(2014)
Toxicogenomics directory of chemically exposed human hepatocytes.
Archives of Toxicology 88, S. 2261-2287.
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Wanninger, Josef,
Liebisch, Gerhard,
Eisinger, Kristina,
Neumeier, Markus,
Aslanidis, Charalampos,
Voggenreiter, Lisa,
Pohl, Rebekka ,
Weiss, Thomas S. ,
Krautbauer, Sabrina und
Büchler, Christa
(2014)
Adiponectin isoforms differentially affect gene expression and lipidome of primary human hepatocytes.
Metabolites 2014 (4), S. 394-407.
Takimoto, Toru,
Zimmermann, Martina,
Armeanu-Ebinger, Sorin,
Bossow, Sascha,
Lampe, Johanna,
Smirnow, Irina,
Schenk, Andrea,
Lange, Sebastian,
Weiss, Thomas S. ,
Neubert, Wolfgang,
Lauer, Ulrich M. und
Bitzer, Michael
(2014)
Attenuated and Protease-Profile Modified Sendai Virus Vectors as a New Tool for Virotherapy of Solid Tumors.
PLoS ONE 9 (3), e90508.
Valletta, Daniela,
Czech, Barbara,
Spruss, Thilo,
Ikenberg, Kristian,
Wild, Peter J.,
Hartmann, Arndt,
Weiss, Thomas S. ,
Oefner, Peter J.,
Müller, Martina,
Bosserhoff, Anja-Katrin und
Hellerbrand, Claus
(2014)
Regulation and function of the atypical cadherin FAT1 in hepatocellular carcinoma.
Carcinogenesis 35, S. 1407-1415.
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2013
Krautbauer, Sabrina,
Eisinger, Kristina,
Lupke, Madeleine,
Wanninger, Josef,
Ruemmele, Petra,
Hader, Yvonne,
Weiss, Thomas S. und
Buechler, Christa
(2013)
Manganese superoxide dismutase is reduced in the liver of male but not female humans and rodents with non-alcoholic fatty liver disease.
Experimental and Molecular Pathology 95 (3), S. 330-335.
Volltext nicht vorhanden.
Damm, Georg,
Pfeiffer, Elisa,
Burkhardt, Britta,
Vermehren, Jan,
Nüssler, Andreas K. und
Weiss, Thomas S.
(2013)
Human parenchymal and non-parenchymal liver cell isolation, culture and characterization.
Hepatology International 7, S. 951-958.
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Haider, Christine,
Grubinger, Markus,
Řezníčková, Eva,
Weiss, Thomas S. ,
Rotheneder, Hans,
Miklos, Walter,
Berger, Walter,
Jorda, Radek,
Zatloukal, Marek,
Gucký, Tomáš,
Strnad, Miroslav,
Kryštof, Vladimír und
Mikulits, Wolfgang
(2013)
Novel Inhibitors of Cyclin-Dependent Kinases Combat Hepatocellular Carcinoma without Inducing Chemoresistance.
Molecular Cancer Therapeutics 12 (10), S. 1947-1957.
Gaetano, Carlo,
Venturelli, Sascha,
Berger, Alexander,
Böcker, Alexander,
Busch, Christian,
Weiland, Timo,
Noor, Seema,
Leischner, Christian,
Schleicher, Sabine,
Mayer, Mascha,
Weiss, Thomas S. ,
Bischoff, Stephan C.,
Lauer, Ulrich M. und
Bitzer, Michael
(2013)
Resveratrol as a Pan-HDAC Inhibitor Alters the Acetylation Status of Jistone Proteins in Human-Derived Hepatoblastoma Cells.
PLoS ONE 8 (8), e73097.
Godoy, Patricio,
Hewitt, Nicola J.,
Albrecht, Ute,
Andersen, Melvin E.,
Ansari, Nariman,
Bhattacharya, Sudin,
Bode, Johannes Georg,
Bolleyn, Jennifer,
Borner, Christoph,
Böttger, Jan,
Braeuning, Albert,
Budinsky, Robert A.,
Burkhardt, Britta,
Cameron, Neil R.,
Camussi, Giovanni,
Cho, Chong-Su,
Choi, Yun-Jaie,
Craig Rowlands, J.,
Dahmen, Uta,
Damm, Georg,
Dirsch, Olaf,
Donato, María Teresa,
Dong, Jian,
Dooley, Steven,
Drasdo, Dirk,
Eakins, Rowena,
Ferreira, Karine Sá,
Fonsato, Valentina,
Fraczek, Joanna,
Gebhardt, Rolf,
Gibson, Andrew,
Glanemann, Matthias,
Goldring, Chris E. P.,
Gómez-Lechón, María José,
Groothuis, Geny M. M.,
Gustavsson, Lena,
Guyot, Christelle,
Hallifax, David,
Hammad, Seddik,
Hayward, Adam,
Häussinger, Dieter,
Hellerbrand, Claus,
Hewitt, Philip,
Hoehme, Stefan,
Holzhütter, Hermann-Georg,
Houston, J. Brian,
Hrach, Jens,
Ito, Kiyomi,
Jaeschke, Hartmut,
Keitel, Verena,
Kelm, Jens M.,
Kevin Park, B.,
Kordes, Claus,
Kullak-Ublick, Gerd A.,
LeCluyse, Edward L.,
Lu, Peng,
Luebke-Wheeler, Jennifer,
Lutz, Anna,
Maltman, Daniel J.,
Matz-Soja, Madlen,
McMullen, Patrick,
Merfort, Irmgard,
Messner, Simon,
Meyer, Christoph,
Mwinyi, Jessica,
Naisbitt, Dean J.,
Nussler, Andreas K.,
Olinga, Peter,
Pampaloni, Francesco,
Pi, Jingbo,
Pluta, Linda,
Przyborski, Stefan A.,
Ramachandran, Anup,
Rogiers, Vera,
Rowe, Cliff,
Schelcher, Celine,
Schmich, Kathrin,
Schwarz, Michael,
Singh, Bijay,
Stelzer, Ernst H. K.,
Stieger, Bruno,
Stöber, Regina,
Sugiyama, Yuichi,
Tetta, Ciro,
Thasler, Wolfgang E.,
Vanhaecke, Tamara,
Vinken, Mathieu,
Weiss, Thomas S. ,
Widera, Agata,
Woods, Courtney G.,
Xu, Jinghai James,
Yarborough, Kathy M. und
Hengstler, Jan G.
(2013)
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.
Archives of Toxicology 87, S. 1315-1530.
Hoffmann, Jasmin,
Boehm, Caroline,
Himmelsbach, Kiyoshi,
Donnerhak, Christian,
Roettger, Hendrik,
Weiss, Thomas S. ,
Ploen, Daniela und
Hildt, Eberhard
(2013)
Identification of α-taxilin as an essential factor for the life cycle of hepatitis B virus.
Journal of Hepatology 59 (5), S. 934-941.
Volltext nicht vorhanden.
Thomas, Maria,
Burk, Oliver,
Klumpp, Britta,
Kandel, Benjamin A.,
Damm, Georg,
Weiss, Thomas S. ,
Klein, Kathrin,
Schwab, Matthias und
Zanger, Ulrich M.
(2013)
Direct Transcriptional Regulation of Human Hepatic Cytochrome P450 3A4 (CYP3A4) by Peroxisome Proliferator–Activated Receptor Alpha (PPARα).
Molecular Pharmacology 83 (3), S. 709-718.
Volltext nicht vorhanden.
Ploen, Daniela,
Hafirassou, Mohamed Lamine,
Himmelsbach, Kiyoshi,
Sauter, Daniel,
Biniossek, Martin L.,
Weiss, Thomas S. ,
Baumert, Thomas F.,
Schuster, Catherine und
Hildt, Eberhard
(2013)
TIP47 plays a crucial role in the life cycle of hepatitis C virus.
Journal of Hepatology 58 (6), S. 1081-1088.
Volltext nicht vorhanden.
Krautbauer, Sabrina,
Wanninger, Josef,
Eisinger, Kristina,
Hader, Yvonne,
Beck, Michael,
Kopp, Andrea,
Schmid, Andreas,
Weiss, Thomas S. ,
Dorn, Christoph und
Buechler, Christa
(2013)
Chemerin is highly expressed in hepatocytes and is induced in non-alcoholic steatohepatitis liver.
Experimental and Molecular Pathology 95 (2), S. 199-205.
Volltext nicht vorhanden.
Dayoub, Rania,
Vogel, Arndt,
Schuett, Jutta,
Lupke, Madeleine,
Spieker, Susannah M.,
Kettern, Nadja,
Hildt, Eberhardt,
Melter, Michael und
Weiss, Thomas S.
(2013)
Nrf2 activates augmenter of liver regeneration (ALR) via antioxidant response element and links oxidative stress to liver regeneration.
Molecular Medicine 19, S. 237-244.
2012
Haybaeck, Johannes,
Weiland, Timo,
Klein, Kathrin,
Zimmermann, Martina,
Speicher, Tobias,
Venturelli, Sascha,
Berger, Alexander,
Bantel, Heike,
Königsrainer, Alfred,
Schenk, Martin,
Weiss, Thomas S. ,
Wendel, Albrecht,
Schwab, Matthias,
Bitzer, Michael und
Lauer, Ulrich M.
(2012)
Selective Protection of Human Liver Tissue in TNF-Targeting of Cancers of the Liver by Transient Depletion of Adenosine Triphosphate.
PLoS ONE 7 (12), e52496.
Berger, Alexander,
Venturelli, Sascha,
Kallnischkies, Mascha,
Böcker, Alexander,
Busch, Christian,
Weiland, Timo,
Noor, Seema,
Leischner, Christian,
Weiss, Thomas S. ,
Lauer, Ulrich M.,
Bischoff, Stephan C. und
Bitzer, Michael
(2012)
Kaempferol, a new nutrition-derived pan-inhibitor of human histone deacetylases.
The Journal of Nutritional Biochemistry 24 (6), S. 977-985.
Volltext nicht vorhanden.
Auer, V. J.,
Janas, E.,
Ninichuk, V.,
Eppler, E.,
Weiss, Thomas S. ,
Kirchner, S.,
Otto, A. M. und
Stangl, M. J.
(2012)
Extracellular factors and immunosuppressive drugs influencing insulin secretion of murine islets.
Clinical and Experimental Immunology 170 (2), S. 238-247.
Chennamsetty, Indumathi,
Kostner, Karam M.,
Claudel, Thierry,
Vinod, Manjula,
Frank, Sasa,
Weiss, Thomas S. ,
Trauner, Michael und
Kostner, Gerhard M.
(2012)
Nicotinic acid inhibits hepatic APOA gene expression: studies in humans and in transgenic mice.
Journal of Lipid Research 53 (11), S. 2405-2412.
Buechler, Christa ,
Wanninger, Josef,
Bauer, Sabrina,
Eisinger, Kristina,
Schacherer, Doris,
Hellerbrand, Claus ,
Weiss, Thomas S. und
Schaffler, Andreas
(2012)
Hepatic Chemerin is Induced in Non-Alcoholic Fatty Liver Disease.
Diabetes 61 (1), A691-A692.
Volltext nicht vorhanden.
Bauer, Sabrina,
Weiss, Thomas S. ,
Wiest, Reiner,
Schacherer, Doris,
Hellerbrand, Claus,
Farkas, Stefan,
Scherer, Marcus N.,
Ritter, Mirko,
Schmitz, Gerd,
Schäffler, Andreas und
Buechler, Christa
(2012)
Corrigendum to “Soluble CD163 is not increased in visceral fat and steatotic liver and is even suppressed by free fatty acids in-vitro” [Exp. Mol. Pathol. 91-3 (2011) 733–739].
Experimental and Molecular Pathology 93 (2), S. 283.
Volltext nicht vorhanden.
Valletta, Daniela,
Czech, Barbara,
Weiss, Thomas S. ,
Bosserhoff, Anja-Katrin und
Hellerbrand, Claus
(2012)
FAT1 EXPRESSION IS INCREASED IN HEPATOCELLULAR CARCINOMA AND PROMOTES TUMORIGENESIS.
In: 47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), APR 18-22, 2012, Barcelona, SPAIN.
Volltext nicht vorhanden.
Melas, Ioannis N.,
Mitsos, Alexander,
Messinis, Dimitris E.,
Weiss, Thomas S. ,
Rodriguez, Julio-Saez und
Alexopoulos, Leonidas G.
(2012)
Construction of large signaling pathways using an adaptive perturbation approach with phosphoproteomic data.
Molecular BioSystems 8 (5), S. 1571-1584.
Volltext nicht vorhanden.
Wanninger, Josef,
Bauer, Sabrina,
Eisinger, Kristina,
Weiss, Thomas S. ,
Walter, Roland,
Hellerbrand, Claus,
Schäffler, Andreas,
Higuchi, Akiko,
Walsh, Kenneth und
Buechler, Christa
(2012)
Corrigendum to “Adiponectin upregulates hepatocyte CMKLR1 which is reduced in human fatty liver” [Molecular and Cellular Endocrinology 349 (2012) 248–254].
Molecular and Cellular Endocrinology 355 (1), S. 190.
Volltext nicht vorhanden.
Weiss, Thomas S. ,
Wanninger, J.,
Neumeier, M.,
Weigert, J.,
Bauer, S.,
Schäffler, A.,
Krempl, C.,
Bleyl, C.,
Aslanidis, C.,
Schölmerich, J. und
Buechler, Christa
(2012)
Corrigendum to "Adiponectin-stimulated CXCL8 release in primary human hepatocytes is regulated by ERK1/ERK2, p38 MAPK, NF-κB, and STAT3 signaling pathways".
American Journal of Physiology-Gastrointestinal and Liver Physiology 302 (3), G406-G406.
Melas, Ioannis N.,
Mitsos, Alexander,
Messinis, Dimitris E.,
Weiss, Thomas S. ,
Rodriguez, Julio-Saez und
Alexopoulos, Leonidas G.
(2012)
Construction of large signaling pathways using an adaptive perturbation approach with phosphoproteomic data (vol 8, pg 1571, 2012).
Molecular BioSystems 8 (12), S. 3345.
Volltext nicht vorhanden.
2011
Wanninger, Josef,
Bauer, Sabrina,
Eisinger, Kristina,
Weiss, Thomas S. ,
Walter, Roland,
Hellerbrand, Claus,
Schäffler, Andreas,
Higuchi, Akiko,
Walsh, Kenneth und
Buechler, Christa
(2011)
Adiponectin upregulates hepatocyte CMKLR1 which is reduced in human fatty liver.
Molecular and Cellular Endocrinology 349 (2), S. 248-254.
Volltext nicht vorhanden.
Klein, Kathrin,
Thomas, Maria,
Winter, Stefan,
Weiss, Thomas S. ,
Schwab, Matthias und
Zanger, Ulrich M.
(2011)
Extensive pathway oriented candidate gene approach allows identification of factors influencing CYP3A4 expression and function.
Drug Metabolism Reviews 43 (2), S. 170.
Volltext nicht vorhanden.
Schlagheck, Julian,
Godoy, Patricio,
Campos, Gisela,
Stöber, Regina,
Hengstler, Jan G.,
Vogt, R.,
Melter, Michael und
Weiss, Thomas S.
(2011)
EXPRESSION OF GOOSECOID, AN EPITHELIAL MESENCHYMAL TRANSITION (EMT)-ASSOCIATED TRANSCRIPTION FACTOR, IS ELEVATED IN HUMAN HEPATOCELLULAR CARCINOMA (HCC).
Transplant International 24 (3), S. 43.
Volltext nicht vorhanden.
Vogt, R.,
Godoy, Patricio,
Campos, Gisela,
Stöber, Regina,
Hengstler, Jan G.,
Melter, Michael und
Weiss, Thomas S.
(2011)
IL-15 MRNA IS ENHANCED IN CIRRHOTIC LIVER - POTENTIAL ROLE FOR HEPATOCARCINOGENESIS.
In: 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), NOV 04-08, 2011, San Francisco, CA.
Volltext nicht vorhanden.
Schnabl, Bernd,
Czech, Barbara,
Valletta, Daniela,
Weiss, Thomas S.,
Kirovski, Georgi und
Hellerbrand, Claus
(2011)
Increased expression of zinc finger protein 267 in non-alcoholic fatty liver disease.
International journal of clinical and experimental pathology 4 (7), S. 661-6.
Walter, Roland,
Wanninger, Josef,
Bauer, Sabrina,
Eisinger, Kristina,
Neumeier, Markus,
Weiss, Thomas S. ,
Amann, Thomas,
Hellerbrand, Claus,
Schäffler, Andreas,
Schölmerich, Jürgen und
Buechler, Christa
(2011)
Adiponectin reduces connective tissue growth factor in human hepatocytes which is already induced in non-fibrotic non-alcoholic steatohepatitis.
Experimental and Molecular Pathology 91 (3), S. 740-744.
Volltext nicht vorhanden.
Hoffart, E.,
Ghebreghiorghis, L.,
Nussler, A. K.,
Thasler, W. E.,
Weiss, Thomas S. ,
Schwab, M. und
Burk, O.
(2011)
Effects of atorvastatin metabolites on induction of drug‐metabolizing enzymes and membrane transporters through human pregnane X receptor.
British Journal of Pharmacology 165 (5), S. 1595-1608.
Bauer, Sabrina,
Weiss, Thomas S. ,
Wiest, Reiner,
Schacherer, Doris,
Hellerbrand, Claus,
Farkas, Stefan,
Scherer, Marcus N.,
Ritter, Mirko,
Schmitz, Gerd,
Schäffler, Andreas und
Buechler, Christa
(2011)
Soluble CD163 is not increased in visceral fat and steatotic liver and is even suppressed by free fatty acids in vitro.
Experimental and Molecular Pathology 91 (3), S. 733-739.
Volltext nicht vorhanden.
Wanninger, Josef,
Weigert, Johanna,
Wiest, Reiner,
Bauer, Sabrina,
Karrasch, Thomas,
Farkas, Stefan,
Scherer, Marcus N.,
Walter, Roland,
Weiss, Thomas S. ,
Hellerbrand, Claus,
Neumeier, Markus,
Schäffler, Andreas und
Buechler, Christa
(2011)
Systemic and hepatic vein galectin-3 are increased in patients with alcoholic liver cirrhosis and negatively correlate with liver function.
Cytokine 55 (3), S. 435-440.
Volltext nicht vorhanden.
Nussler, Andreas K.,
Zeilinger, Katrin,
Schyschka, Lilianna,
Ehnert, Sabrina,
Gerlach, Jörg C.,
Yan, Xueying,
Lee, Serene M. L.,
Ilowski, Maren,
Thasler, Wolfgang E. und
Weiss, Thomas S.
(2011)
Cell therapeutic options in liver diseases: cell types, medical devices and regulatory issues.
Journal of Materials Science: Materials in Medicine 22 (5), S. 1087-1099.
Volltext nicht vorhanden.
Kirovski, Georgi,
Stevens, Axel Peter,
Czech, Barbara,
Dettmer, Katja,
Weiss, Thomas S. ,
Wild, Peter,
Hartmann, Arndt,
Bosserhoff, Anja-Katrin,
Oefner, Peter J. und
Hellerbrand, Claus
(2011)
Down-regulation of methylthioadenosine phosphorylase (MTAP) induces progression of hepatocellular carcinoma via accumulation of 5'-deoxy-5'-methylthioadenosine (MTA).
The American journal of pathology 178 (3), S. 1145-1152.
Volltext nicht vorhanden.
Vogt, R.,
Godoy, Patricio,
Campos, Gisela,
Stöber, Regina,
Hengstler, Jan G.,
Schlagheck, J. M. F.,
Schlitt, H. J.,
Melter, Michael und
Weiss, Thomas S.
(2011)
PATIENTS WITH LIVER CIRRHOSIS DEMONSTRATE HIGH IL-15 MRNA EXPRESSION.
In: 46th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), MAR 30-APR 03, 2011, Berlin, GERMANY.
Volltext nicht vorhanden.
Carvajal-Yepes, Monica,
Himmelsbach, Kiyoshi,
Schaedler, Stephanie,
Ploen, Daniela,
Krause, Janis,
Ludwig, Leopold,
Weiss, Thomas S. ,
Klingel, Karin und
Hildt, Eberhard
(2011)
Hepatitis C Virus Impairs the Induction of Cytoprotective Nrf2 Target Genes by Delocalization of Small Maf Proteins.
Journal of Biological Chemistry 286 (11), S. 8941-8951.
Bucher, Joachim,
Riedmaier, Stephan,
Schnabel, Anke,
Marcus, Katrin,
Vacun, Gabriele,
Weiss, Thomas S. ,
Thasler, Wolfgang E.,
Nüssler, Andreas K.,
Zanger, Ulrich M. und
Reuss, Matthias
(2011)
A systems biology approach to dynamic modeling and inter-subject variability of statin pharmacokinetics in human hepatocytes.
BMC systems biology 5 (1), S. 66.
Wanninger, Josef,
Neumeier, Markus,
Bauer, Sabrina,
Weiss, Thomas S. ,
Eisinger, Kristina,
Walter, Roland,
Dorn, Christoph ,
Hellerbrand, Claus,
Schäffler, Andreas und
Buechler, Christa
(2011)
Adiponectin induces the transforming growth factor decoy receptor BAMBI in human hepatocytes.
FEBS Letters 585 (9), S. 1338-1344.
Volltext nicht vorhanden.
Wanninger, J.,
Neumeier, M.,
Bauer, S.,
Weiss, Thomas S. ,
Hellerbrand, C.,
Schoelmerich, J. und
Buechler, Christa
(2011)
Antifibrotic effects of adiponectin include induction of BMP-activated and membrane bound inhibitor (Bambi) in liver cells which antagonizes TGF-beta activity.
Zeitschrift für Gastroenterologie 49, S. 1-56.
Volltext nicht vorhanden.
Wanninger, Josef,
Neumeier, Markus,
Bauer, S.,
Weiss, Thomas S. ,
Hellerbrand, Claus ,
Schoelmerich, Juergen und
Buechler, Christa
(2011)
Antifibrotic effects of adiponectin include induction of BMP-activated and membrane bound inhibitor (Bambi) in liver cells which antagonizes TGF-beta activity.
Zeitschrift für Gastroenterologie 49 (2), P1_56.
Volltext nicht vorhanden.
Wanninger, Josef,
Walter, Roland,
Bauer, Sabrina,
Eisinger, Kristina,
Schäffler, Andreas,
Dorn, Christoph ,
Weiss, Thomas S. ,
Hellerbrand, Claus und
Buechler, Christa
(2011)
MMP-9 activity is increased by adiponectin in primary human hepatocytes but even negatively correlates with serum adiponectin in a rodent model of non-alcoholic steatohepatitis.
Experimental and Molecular Pathology 91 (2), S. 603-607.
Volltext nicht vorhanden.
Dayoub, Rania ,
Lamlé, J.,
Vogel, A.,
Werner, S.,
Schlitt, H. J.,
Melter, Michael und
Weiss, Thomas S.
(2011)
Nrf2, a transcription factor mainly involved in antioxidant defense, regulates the expression of ALR, Augmenter of Liver Regeneration.
Zeitschrift für Gastroenterologie 49, S. 1-12.
Volltext nicht vorhanden.
2010
Dayoub, Rania ,
Wagner, Hannah,
Bataille, Frauke,
Stöltzing, Oliver,
Spruss, Thilo,
Buechler, Christa ,
Schlitt, Hans-Jürgen und
Weiss, Thomas S.
(2010)
Liver Regeneration Associated Protein (ALR) Exhibits Antimetastatic Potential in Hepatocellular Carcinoma.
Molecular Medicine 17, S. 221-228.
Wanninger, Josef,
Neumeier, Markus,
Hellerbrand, Claus,
Schacherer, Doris,
Bauer, Sabrina,
Weiss, Thomas S. ,
Huber, Hanna,
Schäffler, Andreas,
Aslanidis, Charalampos,
Schölmerich, Jürgen und
Buechler, Christa
(2010)
Lipid accumulation impairs adiponectin-mediated induction of activin A by increasing TGFbeta in primary human hepatocytes.
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1811 (10), S. 626-633.
Volltext nicht vorhanden.
Schaedler, Stephanie,
Krause, Janis,
Himmelsbach, Kiyoshi,
Carvajal-Yepes, Monica,
Lieder, Franziska,
Klingel, Karin,
Nassal, Michael,
Weiss, Thomas S. ,
Werner, Sabine und
Hildt, Eberhard
(2010)
Hepatitis B Virus Induces Expression of Antioxidant Response Element-regulated Genes by Activation of Nrf2.
Journal of Biological Chemistry 285 (52), S. 41074-41086.
Maiwald, Tim,
Schneider, Annette,
Busch, Hauke,
Sahle, Sven,
Gretz, Norbert,
Weiss, Thomas S. ,
Kummer, Ursula und
Klingmüller, Ursula
(2010)
Combining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon α‐induced early antiviral signalling.
The FEBS Journal 277 (22), S. 4741-4754.
Volltext nicht vorhanden.
Feidt, Diana M.,
Klein, Kathrin,
Hofmann, Ute,
Riedmaier, Stephan,
Knobeloch, Daniel,
Thasler, Wolfgang E.,
Weiss, Thomas S. ,
Schwab, Matthias und
Zanger, Ulrich M.
(2010)
Profiling Induction of Cytochrome P450 Enzyme Activity by Statins Using a New Liquid Chromatography-Tandem Mass Spectrometry Cocktail Assay in Human Hepatocytes.
Drug Metabolism and Disposition 38 (9), S. 1589-1597.
Volltext nicht vorhanden.
Kirovski, Georgi,
Gäbele, Erwin,
Dorn, Christoph ,
Moleda, Lukas,
Niessen, Christoph,
Weiss, Thomas S. ,
Wobser, Hella,
Schacherer, Doris,
Buechler, Christa ,
Wasmuth, Hermann E. und
Hellerbrand, Claus
(2010)
Hepatic steatosis causes induction of the chemokine RANTES in the absence of significant hepatic inflammation.
International Journal of Clinical and Experimental Pathology 3 (7), S. 675-680.
Reinartz, Andrea,
Ehling, Josef,
Leue, Andrea,
Liedtke, Christian,
Schneider, Ursula,
Kopitz, Jürgen,
Weiss, Thomas S. ,
Hellerbrand, Claus,
Weiskirchen, Ralf,
Knüchel, Ruth und
Gassler, Nikolaus
(2010)
Lipid-induced up-regulation of human acyl-CoA synthetase 5 promotes hepatocellular apoptosis.
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1801 (9), S. 1025-1035.
Volltext nicht vorhanden.
Dayoub, Rania ,
Groitl, Peter,
Dobner, Thomas,
Bosserhoff, Anja Katrin,
Schlitt, Hans-Jürgen und
Weiss, Thomas S.
(2010)
Foxa2 (HNF-3β) regulates expression of hepatotrophic factor ALR in liver cells.
Biochemical and Biophysical Research Communications 395 (4), S. 465-470.
Volltext nicht vorhanden.
Dayoub, Rania ,
Groitl, Peter,
Dobner, Thomas,
Bosserhoff, Anja Katrin,
Schlitt, Hans-Jürgen und
Weiss, Thomas S.
(2010)
Foxa2 (HNF-3β) regulates expression of hepatotrophic factor ALR in liver cells.
Biochemical and Biophysical Research Communications 395 (4), S. 465-470.
Volltext nicht vorhanden.
Dorn, Christoph ,
Riener, Marc-Oliver,
Kirovski, Georgi,
Saugspier, Michael,
Steib, Kathrin,
Weiss, Thomas S. ,
Gäbele, Erwin,
Kristiansen, Glen,
Hartmann, Arndt und
Hellerbrand, Claus
(2010)
Expression of fatty acid synthase in nonalcoholic fatty liver disease.
International Journal of Clinical and Experimental Pathology 3 (5), S. 505-514.
Ilowski, Maren,
Putz, Christine,
Weiss, Thomas S. ,
Brand, Stephan,
Jauch, Karl-Walter,
Hengstler, Jan G. und
Thasler, Wolfgang Erwin
(2010)
Augmenter of liver regeneration causes different kinetics of ERK1/2 and Akt/PKB phosphorylation than EGF and induces hepatocyte proliferation in an EGF receptor independent and liver specific manner.
Biochemical and Biophysical Research Communications 394 (4), S. 915-920.
Volltext nicht vorhanden.
Dorn, Christoph ,
Kraus, Birgit,
Motyl, Magdalena,
Weiss, Thomas S. ,
Gehrig, Manfred,
Schoelmerich, Juergen,
Heilmann, Jörg und
Hellerbrand, Claus
(2010)
Xanthohumol, a chalcon derived from hops, inhibits hepatic inflammation and fibrosis.
Molecular nutrition & food research 54 (Suppl.), S205-S213.
Volltext nicht vorhanden.
Dorn, Christoph ,
Weiss, Thomas S. ,
Heilmann, Jörg und
Hellerbrand, Claus
(2010)
Xanthohumol, a prenylated chalcone derived from hops, inhibits proliferation, migration and interleukin-8 expression of hepatocellular carcinoma cells.
International journal of oncology 36 (2), S. 435-441.
Volltext nicht vorhanden.
2009
Hackl, Christina,
Mori, Akira,
Moser, Christian,
Lang, Sven A.,
Dayoub, Rania ,
Weiss, Thomas S. ,
Schlitt, Hans J.,
Geissler, Edward K.,
Hellerbrand, Claus und
Stoeltzing, Oliver
(2009)
Effect of heat-shock protein-90 (HSP90) inhibition on human hepatocytes and on liver regeneration in experimental models.
Surgery 147 (5), S. 704-712.
Volltext nicht vorhanden.
Ugocsai, Peter,
Hohenstatt, Antonia,
Paragh, György,
Liebisch, Gerhard ,
Langmann, Thomas,
Wolf, Zsuzsanna,
Weiss, Thomas S. ,
Groitl, Peter,
Dobner, Thomas,
Kasprzak, Piotr M. ,
Göbölös, László,
Falkert, Andreas,
Seelbach-Goebel, Birgit,
Gellhaus, Alexandra,
Winterhager, Elke,
Schmidt, Markus,
Semenza, Gregg L. und
Schmitz, Gerd
(2009)
HIF-1beta determines ABCA1 expression under hypoxia in human macrophages.
The International Journal of Biochemistry & Cell Biology 42 (2), S. 241-252.
Volltext nicht vorhanden.
Hoffart, Ella,
Nuessler, Andreas K.,
Thasler, Wolfgang E.,
Weiss, Thomas S. ,
Schwab, Matthias und
Burk, Oliver
(2009)
Molecular mechanism of cytochrome P450 induction by atorvastatin and atorvastatin metabolites.
In: 16th North American Regional ISSX Meeting, OCT 18-22, 2009, Baltimore, MD.
Volltext nicht vorhanden.
Wanninger, Josef,
Neumeier, Markus,
Weigert, Johanna,
Bauer, Sabrina,
Weiss, Thomas S. ,
Schäffler, Andreas,
Krempl, Corinna,
Bleyl, Cornelia,
Aslanidis, Charalampos,
Schölmerich, Jürgen und
Buechler, Christa
(2009)
Adiponectin-stimulated CXCL8 release in primary human hepatocytes is regulated by ERK1/ERK2, p38 MAPK, NF-κB, and STAT3 signaling pathways.
American Journal of Physiology-Gastrointestinal and Liver Physiology 297 (3), G611-G618.
Slany, Astrid,
Haudek, Verena J.,
Zwickl, Hannes,
Gundacker, Nina C.,
Grusch, Michael,
Weiss, Thomas S. ,
Seir, Katja,
Rodgarkia-Dara, Chantal,
Hellerbrand, Claus und
Gerner, Christopher
(2009)
Cell Characterization by Proteome Profiling Applied to Primary Hepatocytes and Hepatocyte Cell Lines Hep-G2 and Hep-3B.
Journal of Proteome Research 9 (1), S. 6-21.
Volltext nicht vorhanden.
Dorn, C.,
Fleck, M.,
Gäbele, E.,
Weiss, Thomas S. ,
Blank, C. und
Hellerbrand, Claus
(2009)
135 PD1/PD-L1 PROTECT FROM INFLAMMATION AND FIBROSIS IN NON-ALCOHOLIC STEATOHEPATITIS.
Journal of Hepatology 50 (1), S55.
Volltext nicht vorhanden.
Amann, Thomas,
U, U. Maegdefrau,
Hartmann, A.,
Stoeltzing, O.,
Weiss, Thomas S. ,
Schölmerich, Jürgen,
Bosserhoff, Anja-Katrin und
Hellerbrand, Claus
(2009)
504 GLUT1 AND GLUT3 EXPRESSION ARE INCREASED IN HEPATOCELLULAR CARCINOMA AND PROMOTE TUMORIGENICITY.
Journal of Hepatology 50 (1), S188.
Volltext nicht vorhanden.
Dayoub, Rania ,
Hauer, B.,
Schulze, N.,
Dorn, C.,
Buettner, R.,
Hellerbrand, Claus ,
Schlitt, H. J. und
Weiss, Thomas S.
(2009)
700 LIVER REGENERATION AUGMENTING PROTEIN ALR REDUCES LIPOTOXICITY AND PROFIBROGENIC GENE EXPRESSION IN VITRO.
Journal of Hepatology 50 (1), S256-S257.
Volltext nicht vorhanden.
Lauer, Ulrich M.,
Weiss, Thomas S. ,
Bitzer, Michael,
Gregor, Michael,
Königsrainer, Alfred,
Groothuis, Geny M. M.,
Rots, Marianne,
Wehrmann, Manfred,
Wagner, Silvia,
Kupka, Susan,
Smirnow, Irina,
Armeanu-Ebinger, Sorin und
Zimmermann, Martina
(2009)
Human precision-cut liver tumor slices as a tumor patient-individual predictive test system for oncolytic measles vaccine viruses.
International Journal of Oncology 34 (5), S. 1247-1256.
Amann, Thomas,
Mägdefrau, Ulrike,
Hartmann, Arndt,
Agaimy, Abbas,
Marienhagen, Jörg,
Weiss, Thomas S. ,
Stoeltzing, Oliver,
Warnecke, Christina,
Schölmerich, Jürgen,
Oefner, Peter J.,
Kreutz, Marina,
Bosserhoff, Anja-Katrin und
Hellerbrand, Claus
(2009)
GLUT1 expression is increased in hepatocellular carcinoma and promotes tumorigenesis.
The American journal of pathology 174 (4), S. 1544-1552.
Volltext nicht vorhanden.
Maegdefrau, Ulrike,
Amann, Thomas,
Winklmeier, Andreas,
Braig, Simone,
Schubert, Thomas,
Weiss, Thomas S. ,
Schardt, Katharina,
Warnecke, Christina,
Hellerbrand, Claus und
Bosserhoff, Anja‐Katrin
(2009)
Bone morphogenetic protein 4 is induced in hepatocellular carcinoma by hypoxia and promotes tumour progression.
The Journal of Pathology 218 (4), S. 520-529.
Buechler, Christa ,
Schäffler, Andreas,
Johann, Monika,
Neumeier, Markus,
Köhl, Philip,
Weiss, Thomas S. ,
Wodarz, Norbert,
Kiefer, Paul und
Hellerbrand, Claus
(2009)
Elevated adiponectin serum levels in patients with chronic alcohol abuse rapidly decline during alcohol withdrawal.
Journal of Gastroenterology and Hepatology 24 (4), S. 558-563.
Volltext nicht vorhanden.
Wobser, Hella,
Dorn, Christoph ,
Weiss, Thomas S. ,
Amann, Thomas,
Bollheimer, Cornelius,
Büttner, Roland,
Schölmerich, Jürgen und
Hellerbrand, Claus
(2009)
Lipid accumulation in hepatocytes induces fibrogenic activation of hepatic stellate cells.
Cell Research 19 (8), S. 996-1005.
Volltext nicht vorhanden.
2008
Tomé, Daniel,
Santel, Thore,
Pflug, Gabi,
Hemdan, Nasr Y. A.,
Schäfer, Angelika,
Hollenbach, Marcus,
Buchold, Martin,
Hintersdorf, Anja,
Lindner, Inge,
Otto, Andreas,
Bigl, Marina,
Oerlecke, Ilka,
Hutschenreuter, Antje,
Sack, Ulrich,
Huse, Klaus,
Groth, Marco,
Birkemeyer, Claudia,
Schellenberger, Wolfgang,
Gebhardt, Rolf,
Platzer, Mathias,
Weiss, Thomas S. ,
Vijayalakshmi, Mookambeswaran A.,
Krüger, Monika und
Birkenmeier, Gerd
(2008)
Curcumin Inhibits Glyoxalase 1—A Possible Link to Its Anti-Inflammatory and Anti-Tumor Activity.
PLoS ONE 3 (10), e3508.
Armeanu-Ebinger, Sorin,
Krusch, Matthias,
Baltz, Katrin M.,
Weiss, Thomas S. ,
Smirnow, Irina,
Steinle, Alexander,
Lauer, Ulrich M.,
Bitzer, Michael und
Salih, Helmut R.
(2008)
Direct and Natural Killer Cell-Mediated Antitumor Effects of Low-Dose Bortezomib in Hepatocellular Carcinoma.
Clinical Cancer Research 14 (11), S. 3520-3528.
Wanninger, Josef,
Neumeier, Markus,
Weigert, Johanna,
Liebisch, Gerhard,
Weiss, Thomas S. ,
Schäffler, Andreas,
Aslanidis, Charalampos,
Schmitz, Gerd,
Schölmerich, Jürgen und
Buechler, Christa
(2008)
Metformin reduces cellular lysophosphatidylcholine and thereby may lower apolipoprotein B secretion in primary human hepatocytes.
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1781 (6-7), S. 321-325.
Volltext nicht vorhanden.
Dayoub, Rania ,
Dobner, T.,
Groitl, P.,
Thasler, W. E.,
Hellerbrand, Claus ,
Bosserhoff, A. K. ,
Schlitt, H. J. und
Weiss, Thomas S.
(2008)
510 THE FORKHEAD BOX A2 TRANSCRIPTION FACTOR REGULATES THE HEPATOTROPHIC PROTEIN ALR (AUGMENTER OF LIVER REGENERATION).
Journal of Hepatology 48 (2), S193.
Volltext nicht vorhanden.
Weiss, Thomas S. ,
Lichtenauer, M.,
Kirchner, S.,
Stock, P.,
Aurich, H.,
Christ, B.,
Brockhoff, G.,
Kunz-Schughart, L. A.,
Jauch, K.-W.,
Schlitt, H.-J. und
Thasler, W. E.
(2008)
Hepatic progenitor cells from adult human livers for cell transplantation.
Gut 57, S. 1129-1138.
Volltext nicht vorhanden.
Jeschke, Marc G.,
Klein, Dagmar,
Thasler, Wolfgang E.,
Bolder, Ulrich,
Schlitt, Hans-Jürgen,
Jauch, Karl-Walter und
Weiss, Thomas S.
(2008)
Insulin Decreases Inflammatory Signal Transcription Factor Expression in Primary Human Liver Cells after LPS Challenge.
Molecular Medicine 14, S. 11-19.
Gäbele, Erwin,
Mühlbauer, Marcus,
Dorn, Christoph ,
Weiss, Thomas S. ,
Froh, Matthias,
Schnabl, Bernd,
Wiest, Reiner,
Schölmerich, Jürgen,
Obermeier, Florian und
Hellerbrand, Claus
(2008)
Role of TLR9 in hepatic stellate cells and experimental liver fibrosis.
Biochemical and Biophysical Research Communications 376 (2), S. 271-276.
Volltext nicht vorhanden.
2007
Wobser, H.,
Dorn, C.,
Weiss, Thomas S. ,
Bollheimer, C.,
Buettner, R.,
Schoelmerich, J. und
Hellerbrand, Claus
(2007)
[772] LIPID ACCUMULATION IN HEPATOCYTES INDUCES ACTIVATION AND PRO-FIBROTIC GENE EXPRESSION IN HEPATIC STELLATE CELLS - A NEW IN VITRO MODEL TO STUDY FIBROGENESIS IN NASH.
Journal of Hepatology 46 (1), S290.
Volltext nicht vorhanden.
Wobser, Hella,
Dorn, C.,
Weiss, Thomas S. ,
Bollheimer, C.,
Buettner, R.,
Schoelmerich, J. und
Hellerbrand, Claus
(2007)
[772] LIPID ACCUMULATION IN HEPATOCYTES INDUCES ACTIVATION AND PRO-FIBROTIC GENE EXPRESSION IN HEPATIC STELLATE CELLS - A NEW IN VITRO MODEL TO STUDY FIBROGENESIS IN NASH.
Journal of Hepatology 46 (1), S290.
Volltext nicht vorhanden.
Venturelli, Sascha,
Armeanu, Sorin,
Pathil, Anita,
Hsieh, Chih‐Jen,
Weiss, Thomas S. ,
Vonthein, Reinhard,
Wehrmann, Manfred,
Gregor, Michael,
Lauer, Ulrich M. und
Bitzer, Michael
(2007)
Epigenetic combination therapy as a tumor‐selective treatment approach for hepatocellular carcinoma.
Cancer 109 (10), S. 2132-2141.
Volltext nicht vorhanden.
Brand, Stephan,
Dambacher, Julia,
Beigel, Florian,
Zitzmann, Kathrin,
Heeg, Malte H. J.,
Weiss, Thomas S. ,
Prüfer, Thomas,
Olszak, Torsten,
Steib, Christian J.,
Storr, Martin,
Göke, Burkhard,
Diepolder, Helmut,
Bilzer, Manfred,
Thasler, Wolfgang E. und
Auernhammer, Christoph J.
(2007)
IL-22-mediated liver cell regeneration is abrogated by SOCS-1/3 overexpression in vitro.
American Journal of Physiology-Gastrointestinal and Liver Physiology 292 (4), G1019-G1028.
Walbrun, Peter,
Hellerbrand, Claus ,
Weiss, Thomas S. ,
Netter, Susanne,
Neumaier, Daniel,
Gaebele, Erwin,
Wiest, Reiner ,
Schoelmerich, Juergen und
Froh, Matthias
(2007)
Characterization of rat and human Kupffer cells after cryopreservation.
Cryobiology 54 (2), S. 164-172.
Volltext nicht vorhanden.
Neumeier, M.,
Schäffler, A.,
Weigert, J.,
Eggenhofer, E.,
Weiss, Thomas S. ,
Schölmerich, J. und
Buechler, Christa
(2007)
Adiponectin induces IL-6 and CXCL8 in primary human hepatocytes and thereby may alleviate hepatic steatosis.
Experimental and Clinical Endocrinology & Diabetes 115 (S 1).
Volltext nicht vorhanden.
2006
Neumeier, Markus,
Sigruener, Alexander,
Eggenhofer, Elke,
Weigert, Johanna,
Weiss, Thomas S. ,
Schaeffler, Andreas,
Schlitt, Hans J. ,
Aslanidis, Charalampos,
Piso, Pompiliu,
Langmann, Thomas,
Schmitz, Gerd ,
Schölmerich, Jürgen und
Buechler, Christa
(2006)
High molecular weight adiponectin reduces apolipoprotein B and E release in human hepatocytes.
Biochemical and Biophysical Research Communications 352 (2), S. 543-548.
Volltext nicht vorhanden.
Weiss, Thomas S. ,
Cetto, M.,
Zirngibl, Hubert,
Schölmerich, Jürgen,
Jauch, K. W. und
Rogler, Gerhard
(2006)
Polyamine levels in colonic epithelial cells during inflammatory bowel disease (IBD).
Gastroenterology 114 (1), A432.
Walbrun, Peter,
Hellerbrand, Claus ,
Weiss, Thomas S. ,
Netter, Susanne,
Gäbele, Erwin,
Mühlbauer, Marcus,
Wiest, Reiner ,
Schölmerich, Jürgen und
Froh, Matthias
(2006)
Cryopreservation of human kupffer cells.
In: 57th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, OCT 27-31, 2006, Boston, MA.
Volltext nicht vorhanden.
Neumeier, Markus,
Weigert, Johanna,
Schäffler, Andreas,
Weiss, Thomas S. ,
Schmidl, Christian ,
Büttner, Roland,
Bollheimer, Cornelius,
Aslanidis, Charalampos,
Schölmerich, Jürgen und
Buechler, Christa
(2006)
Aldehyde oxidase 1 is highly abundant in hepatic steatosis and is downregulated by adiponectin and fenofibric acid in hepatocytes in vitro.
Biochemical and Biophysical Research Communications 350 (3), S. 731-735.
Volltext nicht vorhanden.
Neumeier, Markus,
Hellerbrand, Claus ,
Gäbele, Erwin,
Buettner, R.,
Bollheimer, Cornelius,
Weigert, Johanna,
Schäffler, Andreas,
Weiss, Thomas S. ,
Lichtenauer, Monika,
Schölmerich, Jürgen und
Buechler, Christa
(2006)
Adiponectin and its receptors in rodent models of fatty liver disease and liver cirrhosis.
World Journal of Gastroenterology 12 (34), S. 5490-5494.
Röhrl, E.,
Bauer, T.,
Böhm, S.,
Weiss, Thomas S. ,
Schlitt, H. und
Jilg, W.
(2006)
P.067 Impact of vaccine-induced HBsAg-specific CD4+ T cells on in vitro hepatitis B-virus infection of primary human hepatocytes.
Journal of Clinical Virology 36 (2), S81-S82.
Volltext nicht vorhanden.
Thasler, Wolfgang E.,
Schlott, Thilo,
Kalkuhl, Arno,
Plän, Thomas,
Irrgang, Bernhard,
Jauch, Karl-Walter und
Weiss, Thomas S.
(2006)
Human Tissue for In Vitro Research as an Alternative to Animal Experiments: A Charitable “Honest Broker” Model to Fulfil Ethical and Legal Regulations and to Protect Research Participants.
Alternatives to Laboratory Animals 34 (4), S. 387-392.
Volltext nicht vorhanden.
Dayoub, Rania,
Thasler, Wolfgang E.,
Bosserhoff, Anja K.,
Singer, Thomas,
Jauch, Karl-Walter,
Schlitt, Hans J. und
Weiss, Thomas S.
(2006)
Regulation of polyamine synthesis in human hepatocytes by hepatotrophic factor augmenter of liver regeneration.
Biochemical and biophysical research communications 345 (1), S. 181-187.
Zugang zum Volltext eingeschränkt.
Bitzer, M. ,
Venturelli, S.,
Armeanu, S.,
Weiss, Thomas S. ,
Gregor, M. und
Lauer, U. M.
(2006)
Combinatorial epigenetic treatment approach for hepatocellular carcinoma.
In: 42nd Annual Meeting of the American-Society-of-Clinical-Oncology, JUN 02-06, 2006, Atlanta, GA.
Volltext nicht vorhanden.
Mühlbauer, Marcus,
Fleck, Martin,
Schütz, Christian,
Weiss, Thomas S. ,
Froh, Matthias,
Blank, Christian,
Schölmerich, Jürgen und
Hellerbrand, Claus
(2006)
PD-L1 is induced in hepatocytes by viral infection and by interferon-α and -γ and mediates T cell apoptosis.
Journal of Hepatology 45 (4), S. 520-528.
Volltext nicht vorhanden.
Büttner, R.,
Neumeier, M.,
Schäffler, A.,
Hellerbrand, Claus ,
Gäbele, E.,
Bollheimer, C.,
Weigert, J.,
Weiss, Thomas S. ,
Lichtenauer, M.,
Schölmerich, J. und
Büchler, Christa
(2006)
Adiponectin and adiponectin receptors AdipoR1 and AdipoR2 in rodent models of fatty liver and liver cirrhosis.
Medizinische Klinik 101 (4), A15.
Volltext nicht vorhanden.
Mühlbauer, M.,
Fleck, M.,
Weiss, Thomas S. ,
Froh, Matthias,
Schütz, C.,
Blank, C.,
Schölmerich, Jürgen und
Hellerbrand, C.
(2006)
PD-L1 expression in human hepatocytes induces T-cell apoptosis.
Medizinische Klinik 101 (4), A23.
Volltext nicht vorhanden.
Pathil, Anita,
Armeanu, Sorin,
Venturelli, Sascha,
Mascagni, Paolo,
Weiss, Thomas S. ,
Gregor, Michael,
Lauer, Ulrich M. und
Bitzer, Michael
(2006)
HDAC inhibitor treatment of hepatoma cells induces both TRAIL-independent apoptosis and restoration of sensitivity to TRAIL.
Hepatology 43 (3), S. 425-434.
Thasler, Wolfgang E.,
Dayoub, Rania,
Mühlbauer, Marcus,
Hellerbrand, Claus,
Singer, Thomas,
Gräbe, Anja,
Jauch, Karl-Walter,
Schlitt, Hans-Jürgen und
Weiss, Thomas S.
(2006)
Repression of cytochrome P450 activity in human hepatocytes in vitro by a novel hepatotrophic factor, augmenter of liver regeneration.
The Journal of pharmacology and experimental therapeutics 316 (2), S. 822-829.
Zugang zum Volltext eingeschränkt.
Hellerbrand, Claus,
Mühlbauer, Marcus,
Wallner, Susanne,
Schuierer, Marion,
Behrmann, Iris,
Bataille, Frauke,
Weiss, Thomas S. ,
Schölmerich, Jürgen und
Bosserhoff, Anja-Katrin
(2006)
Promoter-hypermethylation is causing functional relevant downregulation of methylthioadenosine phosphorylase (MTAP) expression in hepatocellular carcinoma.
Carcinogenesis 27 (1), S. 64-72.
Zugang zum Volltext eingeschränkt.
Thasler, Wolfgang E.,
Weiss, Thomas S. ,
Letschert, K.,
Tausch, U.,
Jilg, Wolfgang,
Hellerbrand, Claus und
Jauch, K. W.
(2006)
The human liver in vitro model: Potential of primary human hepatocytes for experimental and clinical research.
Langenbeck's Archives of Surgery 386 (6), S. 475-476.
Volltext nicht vorhanden.
2005
Mühlbauer, Marcus,
Fleck, M.,
Weiss, Thomas S. ,
Froh, Matthias,
Hoves, Sabine,
Schölmerich, Jürgen und
Hellerbrand, Claus
(2005)
Interferons induce programmed death-1 ligand-1 expression in hepatocytes.
In: 56th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, NOV 11-15, 2005, San Francisco, CA.
Volltext nicht vorhanden.
Mühlbauer, Marcus,
Bosserhoff, Anja K.,
Hartmann, Arndt,
Thasler, Wolfgang E.,
Weiss, Thomas S. ,
Herfarth, Hans,
Lock, Guntram,
Schölmerich, Jürgen und
Hellerbrand, Claus
(2005)
A novel MCP-1 gene polymorphism is associated with hepatic MCP-1 expression and severity of HCV-related liver disease.
Gastroenterology 125 (4), S. 1085-1093.
Neumeier, Markus,
Weigert, Johanna,
Schäffler, Andreas,
Weiss, Thomas S. ,
Kirchner, Stefan,
Laberer, Sabine,
Schölmerich, Jürgen und
Buechler, Christa
(2005)
Regulation of adiponectin receptor 1 in human hepatocytes by agonists of nuclear receptors.
Biochemical and Biophysical Research Communications 334 (3), S. 924-929.
Volltext nicht vorhanden.
Thasler, W. E.,
Schlott, T.,
Thelen, P.,
Hellerbrand, Claus ,
Bataille, F.,
Lichtenauer, M.,
Schlitt, H. J.,
Jauch, K. W. und
Weiss, Thomas S.
(2005)
Expression of augmenter of liver regeneration (ALR) in human liver cirrhosis and carcinoma.
Histopathology 47 (1), S. 57-66.
Volltext nicht vorhanden.
Orr, Samantha,
Alexandre, Eliane,
Clark, Brian J.,
Gray, Neil,
Helin, Heiki,
Ravid, Rivka,
Read, Mel,
Richert, Lysiane,
Roosipuu, Retlav,
Jonsson-Rylander, Ann-Cathrine,
Syring, Carina,
Teesalu, Tambet,
Thasler, Wolfgang E,
Trafford, Jacki,
Van Der Valk, Jan,
Weiss, Thomas S. ,
Womack, Chris und
Ylikomi, Timo
(2005)
Fourth meeting of the European Network of Research Tissue Banks – Future strategy to increase collaborations in the supply of human tissue for biomedical research.
Cell and Tissue Banking 6, S. 131-138.
Volltext nicht vorhanden.
Mühlbauer, Marcus,
Ringel, Susanne,
Hartmann, Arndt,
Lallinger, Gertrud,
Weiss, Thomas S. ,
Gäbele, Erwin,
Wünsch, Peter,
Schölmerich, Jürgen und
Hellerbrand, Claus
(2005)
Lack of association between the functional CX3CR1 polymorphism V249I and hepatocellular carcinoma.
Oncology Reports 13 (5), S. 957-963.
Volltext nicht vorhanden.
Thasler, W. E.,
Schlott, T.,
Thelen, P.,
Bataille, F.,
Lichtenauer, M.,
Schlitt, Hans J. ,
Jauch, K. W. und
Weiss, Thomas S.
(2005)
Human augmenter of liver regeneration is highly expressed in regenerative nodules of liver cirrhosis.
In: 40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver, APR 13-17, 2005, Paris, FRANCE.
Volltext nicht vorhanden.
2004
Armeanu, Sorin,
Pathil, Anita,
Venturelli, Sascha,
Mascagni, Paolo,
Weiss, Thomas S. ,
Göttlicher, Martin,
Gregor, Michael,
Lauer, Ulrich M. und
Bitzer, Michael
(2004)
Apoptosis on hepatoma cells but not on primary hepatocytes by histone deacetylase inhibitors valproate and ITF2357.
Journal of Hepatology 42 (2), S. 210-217.
Volltext nicht vorhanden.
Mühlbauer, Marcus,
Weiss, Thomas S. ,
Thasler, Wolfgang E.,
Gelbmann, Cornelia M.,
Schnabl, Bernd,
Schölmerich, Jürgen und
Hellerbrand, Claus
(2004)
LPS-mediated NFκB activation varies between activated human hepatic stellate cells from different donors.
Biochemical and Biophysical Research Communications 325 (1), S. 191-197.
Volltext nicht vorhanden.
Mühlbauer, Marcus,
Weiss, Thomas S. ,
Thasler, Wolfgang E.,
Gelbmann, Cornelia M.,
Schnabl, Bernd,
Schölmerich, Jürgen und
Hellerbrand, Claus
(2004)
LPS-mediated NFκB activation varies between activated human hepatic stellate cells from different donors.
Biochemical and Biophysical Research Communications 325 (1), S. 191-197.
Volltext nicht vorhanden.
Weiss, Thomas S. ,
Herfarth, H.,
Obermeier, F.,
Ouart, J.,
Vogl, D.,
Schölmerich, Jürgen,
Jauch, K. W. und
Rogler, G.
(2004)
Intracellular Polyamine Levels of Intestinal Epithelial Cells in Inflammatory Bowel Disease.
Inflammatory Bowel Diseases 10 (5), S. 529-535.
Volltext nicht vorhanden.
Froh, Matthias,
Mühlbauer, Marcus,
Stickel, Felix,
Seitz, H. K.,
Hartmann, A.,
Weiss, Thomas S. ,
Schölmerich, Jürgen und
Hellerbrand, Claus
(2004)
Different effects of the functional MCP-1 polymorphism (A-2518G) on hepatic fibrosis and hepatocancerogenesis.
In: Digestive Disease Week/105th Annual Meeting of the American-Gastroenterological-Association, MAY 16-19, 2004, New Orleans, LA.
Volltext nicht vorhanden.
2003
Armeanu, Sorin,
Lauer, Ulrich M.,
Smirnow, Irina,
Schenk, M.,
Weiss, Thomas S. ,
Gregor, M. und
Bitzer, M.
(2003)
Adenoviral gene transfer of tumor necrosis factor-related apoptosis-inducing ligand overcomes an impaired response of hepatoma cells but causes severe apoptosis in primary human hepatocytes.
Cancer Research 63 (10), S. 2369-2372.
Volltext nicht vorhanden.
Thasler, Wolfgang E.,
Weiss, Thomas S. ,
Schillhorn, Kerrin,
Stoll, Peter-Tobias,
Irrgang, Bernhard und
Jauch, Karl-Walter
(2003)
Charitable State-Controlled Foundation Human Tissue and Cell Research: Ethic and Legal Aspects in the Supply of Surgically Removed Human Tissue For Research in the Academic and Commercial Sector in Germany.
Cell and Tissue Banking 4, S. 49-56.
Volltext nicht vorhanden.
2002
Mühlbauer, Marcus,
Thasler, Wolfgang E.,
Weiss, Thomas S. ,
Schölmerich, Jürgen und
Hellerbrand, Claus
(2002)
An in vitro model with kryoconserved human activated hepatic stellate cells: Reflecting heterogeneity of profibrotic and proinflammatory gene expression.
In: 53rd Annual Meeting of the Association-for-the-Study-of-Liver-Diseases (AASLD), NOV 01-05, 2002, BOSTON, MASSACHUSETTS.
Volltext nicht vorhanden.
Orr, Samantha,
Alexandre, Eliane,
Clark, Brain,
Combes, Robert,
Fels, Lueder M.,
Gray, Neil,
Jönsson-Rylander, Ann-Cathrine,
Helin, Heikki,
Koistinen, Jukka,
Oinonen, Teija,
Richert, Lysiane,
Ravid, Rivka,
Salonen, Jarmo,
Teesalu, Tambet,
Thasler, Wolfgang E.,
Trafford, Jacki,
van der Valk, Jan,
von Versen, Rudiger,
Weiss, Thomas S. ,
Womack, Chris und
Ylikomi, Timo
(2002)
The establishment of a network of European human research tissue banks.
Cell and Tissue Banking 3, S. 133-137.
Volltext nicht vorhanden.
Tange, Stefan,
Scherer, Marcus N.,
Graeb, Christian,
Weiss, Thomas S. ,
Justl, Martin,
Frank, Erika,
Andrassy, Joachim,
Jauch, Karl-Walter und
Geissler, Edward K.
(2002)
THE ANTINEOPLASTIC DRUG PACLITAXEL HAS IMMUNOSUPPRESSIVE PROPERTIES THAT CAN EFFECTIVELY PROMOTE ALLOGRAFT SURVIVAL IN A RAT HEART TRANSPLANT MODEL1.
Transplantation 73 (2), S. 216-223.
Volltext nicht vorhanden.
Weiss, Thomas S. ,
Bernhardt, Günther,
Buschauer, Armin,
Thasler, Wolfgang E.,
Dolgner, Doris,
Zirngibl, Hubert und
Jauch, Karl-Walter
(2002)
Polyamine levels of human colorectal adenocarcinomas are correlate with tumor stage and grade,.
International Journal of Colorectal Disease 17 (6), S. 381-387.
Volltext nicht vorhanden.
2001
Weiss, Thomas S. ,
Chamberlain, Chester E.,
Takeda, Tetsuro,
Lin, Ping,
Hahn, Klaus M. und
Farquhar, Marilyn Gist
(2001)
Gαi3 binding to calnuc on Golgi membranes in living cells monitored by fluorescence resonance energy transfer of green fluorescent protein fusion proteins.
Proceedings of the National Academy of Sciences 98 (26), S. 14961-14966.
Kalkuhl, Arno,
Thasler, Wolfgang E.,
Krebsfaenger, N.,
Weiss, Thomas S. ,
Bader, R.,
Jauch, K. W. und
Singer, T.
(2001)
Use of primary rat and human hepatocytes in early peclinical drug safety evaluation.
Naunyn - Schmiedebergs Archives of Pharmacology 363 (4), R163.
Volltext nicht vorhanden.
Anderson, Robert,
Balls, Michael,
Burke, M. Danny,
Cummins, Marie,
Fehily, Deirdre,
Gray, Neil,
de Groot, Marleen G.,
Helin, Heikki,
Hunt, Charles,
Jones, David,
Price, David A. ,
Richert, Lysiane,
Ravid, Rivka,
Shute, David,
Śladowski, Dariusz,
Stone, Helena,
Thasler, Wolfgang E.,
Trafford, Jacki,
van der Valk, Jan,
Weiss, Thomas S. ,
Womack, Chris und
Ylikomi, Timo
(2001)
The Establishment of Human Research Tissue Banking in the UK and Several Western European Countries.
In: ECVAM Workshop 44, 8–10 September 2000, The Belfry, Birmingham, UK.
Volltext nicht vorhanden.
2000
1999
Thasler, Wolfgang E.,
Weiss, Thomas S. ,
Abels, C.,
Hellerbrand, Claus ,
Bolder, U.,
Wagner, J.,
Szeimies, R. M. und
Jauch, Karl-Walter
(1999)
Oxidative cell damage induced by repeated application of 5-aminolevulinic acid in human hepatocyte cultures.
Hepatology 30 (4), 400A.
Volltext nicht vorhanden.
Bäumler, Wolfgang ,
Abels, C.,
Karrer, Sigrid ,
Weiss, Thomas S. ,
Messmann, Helmut,
Landthaler, Michael und
Szeimies, R. M.
(1999)
Photo-oxidative killing of human colonic cancer cells using indocyanine green and infrared light.
British Journal of Cancer 80, S. 360-363.
Thasler, Wolfgang E.,
Letschert, K. C.,
Weiss, Thomas S. ,
Weinberger, K. M.,
Bolder, U. und
Jauch, Karl-Walter
(1999)
Vaccinia mediated gene transfer into human hepatocytes - Efficiency and function under transplant conditions in vitro.
Langenbecks Archives of Surgery (1), S. 247-251.
Volltext nicht vorhanden.
1997
Weiss, Thomas S. ,
Bernhardt, G.,
Buschauer, Armin ,
Spruss, Thilo,
Dolgner, Doris,
Jauch, K. W. und
Zirngibl, H.
(1997)
An in vitro / in vivo model for studying the role of polyamines in human pancreatic carcinoma.
Gastroenterology 112 (4), A1485.
Volltext nicht vorhanden.
1996
Weiss, Thomas S. ,
Heinmoeller, E.,
Buschauer, Armin ,
Bernhardt, Günther ,
Gruber, R.,
Rueschoff, J. und
Zirngibl, H.
(1996)
A new HPLC-method for the determination of polyamines (PA) in the subpicomolar range: PA and ornithine-decarboxylase (ODC) in human pancreatic carcinoma cell lines.
European Journal of Cell Biology 69 (42), S. 157.
Volltext nicht vorhanden.
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