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- Universität Regensburg (80)
- Chemie und Pharmazie (80)
- Institut für Pharmazie (80)
- Lehrstuhl Pharmazeutische / Medizinische Chemie II (Prof. Buschauer) (80)
- Institut für Pharmazie (80)
- Chemie und Pharmazie (80)
Gruppieren nach: Datum | Autoren | Institutionen | Titel eines Journals oder einer Zeitschrift | Dokumentenart | Keine Gruppierung
Anzahl der Einträge in dieser Kategorie: 80.
2025
Seibel-Ehlert, Ulla 
(2025)
Development and Application of Label-free and Label-dependent Assays for Functional Characterization of Histamine Receptors and Ligands.
Dissertation, Universität Regensburg.
Gleixner, Jakob
(2025)
Development of amine-functionalized neuropeptide Y (NPY) Y1R ligands and radio- and fluorescently labeled probes for the NPY Y4R.
Dissertation, Universität Regensburg.
2024
Schindler, Lisa
(2024)
Development of stabilized NTS₁R and CXCR4 PET ligands using Nω-carbamoylated arginines for label attachment.
Dissertation, Universität Regensburg.
2023
Tropmann, Katharina
(2023)
A Step Forward to Unravel Open Histamine H2 Receptor Questions: Synthesis and Biological Evaluation of Novel H2R Ligands Including Radio- and Fluorescence-Labeled Pharmacological Tools.
Dissertation, Universität Regensburg.
Höring, Carina
(2023)
Split-Luciferase Complementation and Molecular Dynamics Studies for the Mini-G Protein-Based Functional Characterization of GPCRs.
Dissertation, Universität Regensburg.
Grätz, Lukas
(2023)
Luminescence-based methods for the investigation of ligand binding and GRK2 recruitment to GPCRs.
Dissertation, Universität Regensburg.
2022
Konieczny, Adam
(2022)
Design, Synthesis and Pharmacological Characterization of Oligopeptidic and Non-Peptidic Neuropeptide Y Y4 Receptor Ligands.
Dissertation, Universität Regensburg.
2021
Bartole, Edith
(2021)
Design, Synthesis and Characterization of Molecular Tools for the Histamine H3 and H4 Receptors – In Particular Radio- and Fluorescent Ligands.
Dissertation, Universität Regensburg.
Buschmann, Jonas
(2021)
Synthesis and pharmacological characterization of argininamide-type neuropeptide Y (NPY) Y1 and Y2 receptor antagonists and synthesis of non-peptide potential NPY Y4 receptor ligands.
Dissertation, Universität Regensburg.
Weinhart, Corinna G.
(2021)
Synthesis and pharmacological characterization of
dibenzodiazepinone-type muscarinic M2-receptor
antagonists conjugated to fluorescent dyes or
small peptides. Dissertation, Universität Regensburg.
Antoni, Frauke
(2021)
Design, Synthesis and Characterization of ABCG2 Inhibitors with a Focus on Water Solubility and Stability in Plasma.
Dissertation, Universität Regensburg.
2020
Biselli, Sabrina
(2020)
Synthesis and Pharmacological Characterization of Subtype-Selective Ligands, Including Radio- and Fluorescence Labeled Ligands, for the Histamine H₂ Receptor.
Dissertation, Universität Regensburg.
Littmann, Timo
(2020)
Towards a method for the simultaneous quantification of Gαq activation β-arrestin2 recruitment.
Dissertation, Universität Regensburg.
Pegoli, Andrea
(2020)
Dibenzodiazepinone-type mAChR ligands: radio- and fluorescence labeling enable unveiling of dualsteric M₂R binding and conjugation to short peptides as an avenue to highly selective M₂R ligands.
Dissertation, Universität Regensburg.
2018
Dukorn, Stefanie
(2018)
Pharmacological tools for the NPY receptors: [³⁵S]GTPγS binding assays, luciferase gene reporter assays and labeled peptides.
Dissertation, Universität Regensburg.
2017
Kuhn, Kilian
(2017)
Molecular Tools for the NPY Y₄ Receptor Derived from the C-Terminus of hPP and from Argininamide-type Y₁R Antagonists.
Dissertation, Universität Regensburg.
Xueke, She
(2017)
Synthesis and pharmacological characterization of dibenzodiazepinone-type heterodimeric and fluorescently labeled muscarinic receptor ligands.
Dissertation, Universität Regensburg.
Wan, Jianfei
(2017)
Synthesis and pharmacological characterization of homo- and hetero-dimeric compounds, targeting the hH₁R and/or hH₄R.
Dissertation, Universität Regensburg.
2016
Lieb, Sebastian
(2016)
Investigations on histamine and neuropeptide Y receptors by label-free and label-dependent methods.
Dissertation, Universität Regensburg.
Plank, Nicole
(2016)
Dimeric histamine H2 receptor agonists as molecular tools and genetically engineered HEK293T cells as an assay platform to unravel signaling pathways of hH1R and hH2R.
Dissertation, Universität Regensburg.
Huber, Stefan
(2016)
Investigations on bendamustine esters as new antitumor agents and the role of ABCG2 as a surrogate marker of breast cancer initiating cells.
Dissertation, Universität Regensburg.
Felixberger, Johannes
(2016)
Luciferase complementation for the determination of arrestin recruitment: Investigations at histamine and NPY receptors.
Dissertation, Universität Regensburg.
2015
Wifling, David
(2015)
Constitutive activity of the human histamine H4 receptor: Molecular modelling, binding and functional studies on wild-type and mutant H4R orthologs.
Dissertation, Universität Regensburg.
2014
Baumeister, Paul
(2014)
Molecular tools for G-protein coupled receptors:Synthesis, pharmacological characterization and [3H]-labeling of subtype-selective ligands for histamine H4 and NPY Y2 receptors. Dissertation, Universität Regensburg.
Thiele, Karinna Marie
(2014)
Charakterisierung Gαi3-gendefizienter Mauslinien.
Dissertation, Universität Regensburg.
Meyer, Carolin
(2014)
Synthesis and structure-activity relationships of inhibitors of bacterial hyaluronidase: An approach to obtain compounds with drug-like properties.
Dissertation, Universität Regensburg.
Bauer, Stefanie
(2014)
Quinoline carboxamides as modulators of Breast Cancer Resistance Protein (ABCG2): Investigations on potency, selectivity, mechanism of action, cytotoxicity, stability and drug-like properties.
Dissertation, Universität Regensburg.
Rothenhöfer, Martin
(2014)
Analytical approaches to the study of hyaluronan and hyaluronidases: Development and application of hyphenated chromatographic and electrophoretic methods.
Dissertation, Universität Regensburg.
2013
Textor, Christian
(2013)
Small molecules as inhibitors of streptococcal hyaluronidase: a computer-assisted and multicomponent synthesis approach.
Dissertation, Universität Regensburg.
Holzammer, Tobias
(2013)
Homology modeling, molecular dynamics simulations and site-directed mutagenesis of histamine H2 receptors.
Dissertation, Universität Regensburg.
Kaske, Melanie
(2013)
In search for potent and selective NPY Y4 receptor ligands: acylguanidines, argininamides and peptide analogs.
Dissertation, Universität Regensburg.
Hamberger, Janina
(2013)
Characterization of mammalian hyaluronidase-2 activity and identification of inhibitors of Streptococcal hyaluronan lyase.
Dissertation, Universität Regensburg.
Nordemann, Uwe
(2013)
Radioligand binding and reporter gene assays for histamine H3 and H4 receptor species orthologs.
Dissertation, Universität Regensburg.
2012
Ertel, Miriam
(2012)
Ambivalence of drug metabolism: Exploration of cilazapril and candesartan prodrugs for transdermal delivery and search for toxic reactive intermediates of N(G)-acylated hetarylpropylguanidines.
Dissertation, Universität Regensburg.
2011
Brunskole, Irena
(2011)
Molecular and cellular analysis of aminergic G protein-coupled receptors: histamine H2, H4 and β2-adrenergic receptors, a scientific paradigm.
Dissertation, Universität Regensburg.
Geyer, Roland
(2011)
Hetarylalkyl(aryl)cyanoguanidines as histamine H4 receptor ligands: Synthesis, chiral separation, pharmacological characterization, structure-activity and -selectivity relationships.
Dissertation, Universität Regensburg.
Pluym, Nikola
(2011)
Application of the guanidine–acylguanidine bioisosteric approach to NPY Y2 receptor antagonists: bivalent, radiolabeled and fluorescent pharmacological tools.
Dissertation, Universität Regensburg.
Birnkammer, Tobias
(2011)
Highly potent and selective acylguanidine-type histamine H2 receptor agonists: synthesis and structure-activity relationships of mono- and bivalent ligands.
Dissertation, Universität Regensburg.
Lopuch, Miroslaw
(2011)
Investigations on neuropeptide Y and histamine receptors by fluorescence-based and radiochemical methods.
Dissertation, Universität Regensburg.
Posavec, Damir
(2011)
Adjustment of the decay kinetics of photogenerated endoperoxides embedded in various carrier materials aiming at medical applications.
Dissertation, Universität Regensburg.
Erdmann, Daniela
(2011)
Histamine H2- and H3-receptor antagonists: Synthesis and characterization of radiolabelled and fluorescent pharmacological tools.
Dissertation, Universität Regensburg.
2010
Pop, Nathalie
(2010)
Development of functional assays for human neuropeptide Y (Y1,2,4,5) receptors exploiting GTPase activity and (bio)luminescence as readout.
Dissertation, Universität Regensburg.
Höcherl, Peter
(2010)
New tariquidar-like ABCB1 modulators in cancer chemotherapy:Preclinical pharmacokinetic, pharmacodynamic investigations and computational studies. Dissertation, Universität Regensburg.
Kühnle, Matthias
(2010)
Experimental therapy and detection of glioblastoma: investigation of nanoparticles, ABCG2 modulators and optical imaging of intracerebral xenografts.
Dissertation, Universität Regensburg.
Dayoub, Rania
(2010)
Expression and regulation of liver regeneration associated protein ALR under patho-physiological conditions.
Dissertation, Universität Regensburg.
2009
Mosandl, Johannes
(2009)
Radiochemical and luminescence-based binding and functional assays for human histamine receptors using genetically engineered cells.
Dissertation, Universität Regensburg.
Memminger, Martin
(2009)
Synthesis and characterization of subtype-selective estrogen receptor ligands and their application as pharmacological tools - Cross-talk between estrogen and NPY Y1 receptors in human breast cancer cells.
Dissertation, Universität Regensburg.
Keller, Max
(2009)
Guanidine-acylguanidine bioisosteric approach to address peptidergic receptors: pharmacological and diagnostic tools for the NPY Y1 receptor and versatile building blocks based on arginine substitutes.
Dissertation, Universität Regensburg.
Igel, Patrick
(2009)
Synthesis and structure-activity relationships of NG-acylated arylalkylguanidines and related compounds as histamine receptor ligands: searching for selective H4R agonists.
Dissertation, Universität Regensburg.
2008
Kraus, Anja
(2008)
Highly potent, selective acylguanidine-type histamine H2 receptor agonists: synthesis and structure-activity relationships.
Dissertation, Universität Regensburg.
Spickenreither, Martin
(2008)
Inhibitors of bacterial and mammalian hyaluronidases: design, synthesis and structure-activity relationships with focus on human enzymes.
Dissertation, Universität Regensburg.
2007
Kiewitz, Sebastian Donatus
(2007)
Structural investigations of the Id helix-loop-helix dimerization domain.
Dissertation, Universität Regensburg.
Preuß, Hendrik
(2007)
Species-selective interactions of histamine H2 receptors with guanidine-type agonists: molecular modelling, site-directed mutagenesis and pharmacological analysis.
Dissertation, Universität Regensburg.
Müller, Christine
(2007)
New approaches to the therapy of glioblastoma: investigations on RNA interference, kinesin Eg5 and ABCB1/ABCG2 inhibition.
Dissertation, Universität Regensburg.
Colombo, Noemi
(2007)
Synthesis and conformational analysis of polypeptides related to the inhibitor of the DNA binding and cell differentiation Id2.
Dissertation, Universität Regensburg.
Svobodová, Jaroslava
(2007)
Id3, inhibitor of DNA binding and cell differentiation: synthesis and conformational analysis of the full-length protein and its truncated analogues.
Dissertation, Universität Regensburg.
Hofinger, Edith
(2007)
Recombinant expression, purification and characterization of human hyaluronidases.
Dissertation, Universität Regensburg.
2006
Brennauer, Albert
(2006)
Acylguanidines as bioisosteric groups in argininamide-type neuropeptide Y Y1 and Y2 receptor antagonists: synthesis, stability and pharmacological activity.
Dissertation, Universität Regensburg.
Schulz, Berta
(2006)
Untersuchungen zur Opsonin-Aktivität von CRP, SAP, A-beta42 und SAA und deren Rolle bei der Schaumzellbildung.
Dissertation, Universität Regensburg.
Ghorai, Prasanta
(2006)
Arpromidine-related acylguanidines: synthesis and structure-activity relationships of a new class of guanidine-type histamine H2 receptor agonists with reduced basicity.
Dissertation, Universität Regensburg.
Gross, Dietmar
(2006)
New approaches to the chemotherapy of glioblastoma: investigations on doxorubicin nanoparticles, inhibition of PDGF receptors and kinesin Eg5, with emphasis on confocal laser-scanning microscopy.
Dissertation, Universität Regensburg.
Ziemek, Ralf
(2006)
Development of binding and functional assays for the neuropeptide Y Y 2 and Y 4 receptors.
Dissertation, Universität Regensburg.
Grandl, Margot
(2006)
Influence of E-LDL and Ox-LDL on the metabolism of ApoE, cholesterol, sphingolipids and glycosphingolipids as well as on the raft-composition in human macrophages.
Dissertation, Universität Regensburg.
Zimmermann, Jochen
(2006)
Furan- and pyran-based heterocycles as subtype-selective ligands of the estrogen receptor. Synthesis and biological characterisation.
Dissertation, Universität Regensburg.
Schifferer, Rainer
(2006)
Charakterisierung des zellulären Lipideffluxes von primären, humanen Fibroblasten und Monozyten/Makrophagen.
Dissertation, Universität Regensburg.
Braun, Stephan
(2006)
New inhibitors of bacterial hyaluronidase - synthesis and structure-activity relationships.
Dissertation, Universität Regensburg.
2005
Maa Bared, Salim
(2005)
Identification and characterization of ABCA1-interactive proteins and their relevance to atherosclerosis.
Dissertation, Universität Regensburg.
Hoechstetter, Julia
(2005)
Characterisation of bovine testicular hyaluronidase and a hyaluronate lyase from Streptococcus agalactiae. Investigations on the effect of pH on hyaluronan degradation and preclinical studies on the adjuvant administration of the enzymes in cancer chemotherapy.
Dissertation, Universität Regensburg.
Pollak, Nils
(2005)
Die Rolle von MIF (macrophage migration inhibitory factor) in der Sepsis-induzierten Immunparalyse.
Dissertation, Universität Regensburg.
Hubensack, Martina
(2005)
Approaches to overcome the blood-brain barrier in the chemotherapy of primary and secondary brain tumors: Modulation of P-glycoprotein 170 and targeting of the transferrin receptor.
Dissertation, Universität Regensburg.
Hantschel, Markus
(2005)
Durchflusszytometrische Analysen zur Expression des Hitzeschockproteins Hsp70 auf der Zelloberfläche von kolorektalen Primärtumoren und hepatischen Metastasen, Magenkarzinomen, Bronchialkarzinomen, Kopf-Hals-Tumoren und akuten myeloischen Leukämien.
Dissertation, Universität Regensburg.
2004
Wieser, Carsten
(2004)
Herpesvirus saimiri basierte Vektoren für die somatische Gentherapie der Rheumatoiden Arthritis.
Dissertation, Universität Regensburg.
Botzki, Alexander
(2004)
Structure-based design of hyaluronidase inhibitors.
Dissertation, Universität Regensburg.
Salmen, Sunnhild
(2004)
Inhibitors of bacterial and mammalian hyaluronidase - Synthesis and structure-activity relationships.
Dissertation, Universität Regensburg.
2003
Hähnel, Viola
(2003)
Die transkriptionelle Regulation der Toll-like Rezeptoren (TLR2, TLR3 und TLR4) in mononukleären Phagozyten.
Dissertation, Universität Regensburg.
Graichen, Florian
(2003)
Neuropeptid Y Y1-Rezeptorantagonisten der Argininamid-Reihe: Entwicklung von Synthesemethoden an polymeren Trägern und Strategien zur Herstellung von Radioliganden.
Dissertation, Universität Regensburg.
Stopfer, Peter
(2003)
Biologische Wirkungen der Aktivierung des Lymphotoxin-beta-Rezeptors.
Dissertation, Universität Regensburg.
Heinz, Sven
(2003)
Identification and characterization of genes with specific expression in dendritic cells.
Dissertation, Universität Regensburg.
2002
Mayer, Matthias
(2002)
Entwicklung fluorimetrischer Methoden zur Bestimmung der Affinität und Aktivität von Liganden G-Protein-gekoppelter Rezeptoren an intakten Zellen.
Dissertation, Universität Regensburg.
Kießling, Stephan
(2002)
Funktionelle Untersuchungen zur Expression des Interleukin-11 Rezeptors alpha in humanen Kolonepithelzellen.
Dissertation, Universität Regensburg.
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