Number of items at this level: 84.
Article
Ousingsawat, Jiraporn ,
Centeio, Raquel,
Reyne, Nicole,
McCarron, Alexandra,
Cmielewski, Patricia,
Schreiber, Rainer ,
diStefano, Gabriella,
Römermann, Dorothee,
Seidler, Ursula,
Donnelley, Martin and
Kunzelmann, Karl
(2024)
Inhibition of mucus secretion by niclosamide and benzbromarone in airways and intestine.
Scientific Reports 14 (1).
Jo, Sungwoo,
Centeio, Raquel,
Park, Jinhong,
Ousingsawat, Jiraporn,
Jeon, Dong‐kyu,
Talbi, Khaoula,
Schreiber, Rainer,
Ryu, Kunhi,
Kahlenberg, Kristin,
Somoza, Veronika ,
Delpiano, Livia ,
Gray, Michael A.,
Amaral, Margarida D. ,
Railean, Violeta,
Beekman, Jeffrey M.,
Rodenburg, Lisa W.,
Namkung, Wan and
Kunzelmann, Karl
(2022)
The SLC26A9 inhibitor S9‐A13 provides no evidence for a role of SLC26A9 in airway chloride secretion but suggests a contribution to regulation of ASL pH and gastric proton secretion.
The FASEB Journal 36 (11), e22534.
Ousingsawat, Jiraporn ,
Centeio, Raquel,
Cabrita, Inês ,
Talbi, Khaoula,
Zimmer, Oliver ,
Graf, Moritz,
Göpferich, Achim ,
Schreiber, Rainer and
Kunzelmann, Karl
(2022)
Airway Delivery of Hydrogel-Encapsulated Niclosamide for the Treatment of Inflammatory Airway Disease.
International Journal of Molecular Sciences 23 (3), p. 1085.
Leitzke, Sinje,
Seidel, Jana,
Ahrens, Björn,
Schreiber, Rainer,
Kunzelmann, Karl,
Sperrhacke, Maria,
Bhakdi, Sucharit and
Reiss, Karina
(2022)
Influence of Anoctamin-4 and -9 on ADAM10 and ADAM17 Sheddase Function.
Membranes 12 (2), p. 123.
Fulltext not available.
Talbi, Khaoula,
Cabrita, Inês,
Kraus, Andre,
Hofmann, Sascha,
Skoczynski, Kathrin,
Kunzelmann, Karl ,
Buchholz, Bjoern and
Schreiber, Rainer
(2021)
The chloride channel CFTR is not required for cyst growth in an ADPKD mouse model.
The FASEB Journal 35 (10), pp. 1-12.
Kunzelmann, Karl ,
Centeio, Raquel,
Ousingsawat, Jiraporn ,
Cabrita, Inês ,
Schreiber, Rainer ,
Talbi, Khaoula,
Benedetto, Roberta,
Doušová, Tereza ,
Verbeken, Eric K.,
De Boeck, Kris and
Cohen, Isaac
(2021)
Mucus Release and Airway Constriction by TMEM16A May Worsen Pathology in Inflammatory Lung Disease.
International Journal of Molecular Sciences 22 (7852), pp. 1-18.
Grosch, Melanie,
Brunner, Katrin,
Ilyaskin, Alexandr V. ,
Schober, Michael,
Staudner, Tobias,
Schmied, Denise,
Stumpp, Tina,
Schmidt, Kerstin N.,
Madej, M. Gregor ,
Pessoa, Thaissa D.,
Othmen, Helga,
Kubitza, Marion,
Osten, Larissa,
de Vries, Uwe,
Mair, Magdalena M. ,
Somlo, Stefan,
Moser, Markus,
Kunzelmann, Karl,
Ziegler, Christine ,
Haerteis, Silke,
Korbmacher, Christoph and
Witzgall, Ralph
(2021)
A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts.
Journal of Cell Science 134 (16).
Fulltext not available.
Pereira, Catarina ,
Mazein, Alexander,
Farinha, Carlos M.,
Gray, Michael A.,
Kunzelmann, Karl,
Ostaszewski, Marek,
Balaur, Irina,
Amaral, Margarida D. and
Falcao, Andre O.
(2021)
CyFi-MAP: an interactive pathway-based resource for cystic fibrosis.
Scientific Reports 11 (1).
Fulltext not available.
Cabrita, Inês,
Benedetto, Roberta,
Wanitchakool, Podchanart,
Lerias, Joana,
Centeio, Raquel,
Ousingsawat, Jiraporn,
Schreiber, Rainer and
Kunzelmann, Karl
(2021)
TMEM16A Mediates Mucus Production in Human Airway Epithelial Cells.
American Journal of Respiratory Cell and Molecular Biology 64 (1), pp. 50-58.
Fulltext not available.
Berg, Peder ,
Svendsen, Samuel L.,
Sorensen, Mads Vaarby ,
Schreiber, Rainer,
Kunzelmann, Karl and
Leipziger, Jens
(2021)
The molecular mechanism of CFTR‐ and secretin‐dependent renal bicarbonate excretion.
The Journal of Physiology 599 (12), pp. 3003-3011.
Fulltext not available.
Cabrita, Ines,
Kraus, Andre,
Scholz, Julia Katharina,
Skoczynski, Kathrin,
Schreiber, Rainer,
Kunzelmann, Karl and
Buchholz, Björn
(2020)
Cyst growth in ADPKD is prevented by pharmacological and genetic inhibition of TMEM16A in vivo.
Nature Communications 11, p. 4320.
Oliver, Paula M.,
Neubert, Patrick,
Homann, Arne,
Wendelborn, David,
Bär, Anna-Lorena ,
Krampert, Luka ,
Trum, Maximilian,
Schröder, Agnes,
Ebner, Stefan,
Weichselbaum, Andrea,
Schatz, Valentin,
Linz, Peter,
Veelken, Roland,
Schulte-Schrepping, Jonas ,
Aschenbrenner, Anna C.,
Quast, Thomas,
Kurts, Christian,
Geisberger, Sabrina,
Kunzelmann, Karl,
Hammer, Karin,
Binger, Katrina J.,
Titze, Jens,
Müller, Dominik N.,
Kolanus, Waldemar ,
Schultze, Joachim L.,
Wagner, Stefan and
Jantsch, Jonathan
(2020)
NCX1 represents an ionic Na+ sensing mechanism in macrophages.
PLOS Biology 18 (6), e3000722.
Pinto, Madalena C. ,
Schreiber, Rainer,
Lerias, Joana,
Ousingsawat, Jiraporn,
Duarte, Aires,
Amaral, Margarida and
Kunzelmann, Karl
(2020)
Regulation of TMEM16A by CK2 and Its Role in Cellular Proliferation.
Cells 9 (5), p. 1138.
Centeio, Raquel,
Cabrita, Inês,
Benedetto, Roberta,
Talbi, Khaoula,
Ousingsawat, Jiraporn,
Schreiber, Rainer,
Sullivan, John K. and
Kunzelmann, Karl
(2020)
Pharmacological Inhibition and Activation of the Ca2+ Activated Cl− Channel TMEM16A.
International Journal of Molecular Sciences 21 (7), p. 2557.
Silva, Iris A. L.,
Duarte, Aires,
Marson, Fernando A. L. ,
Centeio, Raquel,
Doušová, Tereza,
Kunzelmann, Karl and
Amaral, Margarida D.
(2020)
Assessment of Distinct Electrophysiological Parameters in Rectal Biopsies for the Choice of the Best Diagnosis/Prognosis Biomarkers for Cystic Fibrosis.
Frontiers in Physiology 11.
Fulltext not available.
Ormel, Lasse,
Lauritzen, Knut H.,
Schreiber, Rainer,
Kunzelmann, Karl and
Gundersen, Vidar
(2020)
GABA, but Not Bestrophin-1, Is Localized in Astroglial Processes in the Mouse Hippocampus and the Cerebellum.
Frontiers in Molecular Neuroscience 13.
Fulltext not available.
Berg, Peder,
Svendsen, Samuel L.,
Sorensen, Mads V. ,
Larsen, Casper K.,
Andersen, Jesper Frank,
Jensen-Fangel, Søren,
Jeppesen, Majbritt,
Schreiber, Rainer,
Cabrita, Ines,
Kunzelmann, Karl and
Leipziger, Jens
(2020)
Impaired Renal HCO3- Excretion in Cystic Fibrosis.
Journal of the American Society of Nephrology 31 (8), pp. 1711-1727.
Fulltext not available.
Sousa, Luis ,
Pankonien, Ines ,
Clarke, Luka A. ,
Silva, Iris ,
Kunzelmann, Karl and
Amaral, Margarida D.
(2020)
KLF4 Acts as a wt-CFTR Suppressor through an AKT-Mediated Pathway.
Cells 9 (7), p. 1607.
Fulltext not available.
Silva, Iris A.L.,
Doušová, Tereza,
Ramalho, Sofia,
Centeio, Raquel,
Clarke, Luka A. ,
Railean, Violeta,
Botelho, Hugo M.,
Holubová, Andrea,
Valášková, Iveta,
Yeh, Jiunn-Tyng,
Hwang, Tzyh-Chang,
Farinha, Carlos M.,
Kunzelmann, Karl and
Amaral, Margarida D.
(2020)
Organoids as a personalized medicine tool for ultra-rare mutations in cystic fibrosis: The case of S955P and 1717-2A>G.
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1866 (11), p. 165905.
Fulltext not available.
Park, Julien H,
Ousingsawat, Jiraporn,
Cabrita, Inês,
Bettels, Ruth E,
Große-Onnebrink, Jörg,
Schmalstieg, Christian,
Biskup, Saskia,
Reunert, Janine,
Rust, Stephan,
Schreiber, Rainer,
Kunzelmann, Karl and
Marquardt, Thorsten
(2020)
TMEM16A deficiency: a potentially fatal neonatal disease resulting from impaired chloride currents.
Journal of Medical Genetics 58 (4), pp. 247-253.
Fulltext not available.
Benedetto, Roberta,
Centeio, Raquel,
Ousingsawat, Jiraporn,
Schreiber, Rainer,
Kunzelmann, Karl and
make_name_string expected hash reference
(2020)
Transport properties in CFTR−/− knockout piglets suggest normal airway surface liquid pH and enhanced amiloride-sensitive Na+ absorption.
Pflügers Archiv - European Journal of Physiology 472, pp. 1507-1519.
Kunzelmann, Karl ,
Centeio, Raquel,
Wanitchakool, Podchanart,
Cabrita, Inês,
Benedetto, Roberta,
Saha, Tultul,
Hoque, Kazi Mirajul and
Schreiber, Rainer
(2019)
Control of Ion Transport by Tmem16a Expressed in Murine Intestine.
Frontiers in Physiology 10 (1262), pp. 1-10.
Bleibaum, Florian ,
Sommer, Anselm,
Veit, Martin,
Rabe, Björn,
Andrä, Jörg,
Kunzelmann, Karl,
Nehls, Christian,
Correa, Wilmar,
Gutsmann, Thomas,
Grötzinger, Joachim,
Bhakdi, Sucharit,
Reiss, Karina and
Fu, Haian
(2019)
ADAM10 sheddase activation is controlled by cell membrane asymmetry.
Journal of Molecular Cell Biology 11 (11), pp. 979-993.
Fulltext not available.
Nagy, Magdolna,
van Geffen, Johanna P.,
Stegner, David ,
Adams, David J.,
Braun, Attila,
de Witt, Susanne M.,
Elvers, Margitta,
Geer, Mitchell J. ,
Kuijpers, Marijke J. E.,
Kunzelmann, Karl,
Mori, Jun,
Oury, Cécile,
Pircher, Joachim,
Pleines, Irina,
Poole, Alastair W.,
Senis, Yotis A.,
Verdoold, Remco,
Weber, Christian ,
Nieswandt, Bernhard,
Heemskerk, Johan W. M. and
Baaten, Constance C. F. M. J.
(2019)
Comparative Analysis of Microfluidics Thrombus Formation in Multiple Genetically Modified Mice: Link to Thrombosis and Hemostasis.
Frontiers in Cardiovascular Medicine 6.
Fulltext not available.
Miner, Kent,
Labitzke, Katja,
Liu, Benxian,
Wang, Paul,
Henckels, Kathryn,
Gaida, Kevin,
Elliott, Robin,
Chen, Jian Jeffrey,
Liu, Longbin,
Leith, Anh,
Trueblood, Esther,
Hensley, Kelly,
Xia, Xing-Zhong,
Homann, Oliver,
Bennett, Brian,
Fiorino, Mike,
Whoriskey, John,
Yu, Gang,
Escobar, Sabine,
Wong, Min,
Born, Teresa L.,
Budelsky, Alison,
Comeau, Mike,
Smith, Dirk,
Phillips, Jonathan ,
Johnston, James A.,
McGivern, Joseph G.,
Weikl, Kerstin,
Powers, David,
Kunzelmann, Karl,
Mohn, Deanna,
Hochheimer, Andreas and
Sullivan, John K.
(2019)
Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide Are Potent TMEM16A Antagonists That Fully Bronchodilate Airways.
Frontiers in Pharmacology 10.
Fulltext not available.
Schreiber, Rainer,
Buchholz, Björn,
Kraus, Andre,
Schley, Gunnar,
Scholz, Julia,
Ousingsawat, Jiraporn and
Kunzelmann, Karl
(2019)
Lipid Peroxidation Drives Renal Cyst Growth In Vitro through Activation of TMEM16A.
Journal of the American Society of Nephrology 30 (2), pp. 228-242.
Fulltext not available.
Benedetto, Roberta,
Ousingsawat, Jiraporn,
Cabrita, Inês,
Pinto, Madalena,
Lérias, Joana R.,
Wanitchakool, Podchanart,
Schreiber, Rainer and
Kunzelmann, Karl
(2019)
Plasma membrane–localized TMEM16 proteins are indispensable for expression of CFTR.
Journal of Molecular Medicine 97 (5), pp. 711-722.
Fulltext not available.
Lérias, Joana R.,
Pinto, Madalena C. ,
Botelho, Hugo M. ,
Awatade, Nikhil T.,
Quaresma, Margarida C.,
Silva, Iris A.L. ,
Wanitchakool, Podchanart,
Schreiber, Rainer,
Pepperkok, Rainer,
Kunzelmann, Karl and
Amaral, Margarida D.
(2018)
A novel microscopy-based assay identifies extended synaptotagmin-1 (ESYT1) as a positive regulator of anoctamin 1 traffic.
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1865 (2), pp. 421-431.
Fulltext not available.
Veit, Martin,
Koyro, Katharina Isabelle,
Ahrens, Björn,
Bleibaum, Florian,
Munz, Martin,
Rövekamp, Hagen,
Andrä, Jörg,
Schreiber, Rainer,
Kunzelmann, Karl,
Sommer, Anselm,
Bhakdi, Sucharit and
Reiss, Karina
(2018)
Anoctamin-6 regulates ADAM sheddase function.
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1865 (11), pp. 1598-1610.
Fulltext not available.
Simões, Filipa,
Ousingsawat, Jiraporn,
Wanitchakool, Podchanart,
Fonseca, Ana ,
Cabrita, Inês,
Benedetto, Roberta,
Schreiber, Rainer and
Kunzelmann, Karl
(2018)
CFTR supports cell death through ROS-dependent activation of TMEM16F (anoctamin 6).
Pflügers Archiv - European Journal of Physiology 470 (2), pp. 305-314.
Fulltext not available.
Lérias, Joana ,
Pinto, Madalena ,
Benedetto, Roberta,
Schreiber, Rainer,
Amaral, Margarida ,
Aureli, Massimo and
Kunzelmann, Karl
(2018)
Compartmentalized crosstalk of CFTR and TMEM16A (ANO1) through EPAC1 and ADCY1.
Cellular Signalling 44, pp. 10-19.
Fulltext not available.
Kraus, Andre,
Peters, Dorien J.M.,
Klanke, Bernd,
Weidemann, Alexander,
Willam, Carsten,
Schley, Gunnar,
Kunzelmann, Karl,
Eckardt, Kai-Uwe and
Buchholz, Bjoern
(2018)
HIF-1α promotes cyst progression in a mouse model of autosomal dominant polycystic kidney disease.
Kidney International 94 (5), pp. 887-899.
Fulltext not available.
Schenk, Laura K.,
Buchholz, Bjoern,
Henke, Sebastian F.,
Michgehl, Ulf,
Daniel, Christoph ,
Amann, Kerstin,
Kunzelmann, Karl and
Pavenstädt, Hermann
(2018)
Nephron-specific knockout of TMEM16A leads to reduced number of glomeruli and albuminuria.
American Journal of Physiology-Renal Physiology 315 (6), F1777-F1786.
Fulltext not available.
von Mässenhausen, Anne,
Tonnus, Wulf,
Himmerkus, Nina,
Parmentier, Simon,
Saleh, Danish,
Rodriguez, Diego,
Ousingsawat, Jiraporn,
Ang, Rosalind L.,
Weinberg, Joel M.,
Sanz, Ana B. ,
Ortiz, Alberto,
Zierleyn, Adrian,
Becker, Jan Ulrich,
Baratte, Blandine,
Desban, Nathalie,
Bach, Stéphane,
Schiessl, Ina Maria ,
Nogusa, Shoko,
Balachandran, Siddharth,
Anders, Hans Joachim,
Ting, Adrian T.,
Bleich, Markus ,
Degterev, Alexei,
Kunzelmann, Karl,
Bornstein, Stefan R.,
Green, Douglas R. ,
Hugo, Christian and
Linkermann, Andreas
(2018)
Phenytoin inhibits necroptosis.
Cell Death & Disease 9 (3).
Fulltext not available.
Hagmann, Henning,
Mangold, Nicole,
Rinschen, Markus M. ,
Koenig, Tim,
Kunzelmann, Karl,
Schermer, Bernhard ,
Benzing, Thomas and
Brinkkoetter, Paul T.
(2018)
Proline‐dependent and basophilic kinases phosphorylate human TRPC6 at serine 14 to control channel activity through increased membrane expression.
The FASEB Journal 32 (1), pp. 208-219.
Fulltext not available.
Schenk, Laura K.,
Ousingsawat, Jiraporn,
Skryabin, Boris V. ,
Schreiber, Rainer,
Pavenstädt, Hermann and
Kunzelmann, Karl
(2018)
Regulation and Function of TMEM16F in Renal Podocytes.
International Journal of Molecular Sciences 19, p. 1798.
Ousingsawat, Jiraporn,
Cabrita, Inês,
Wanitchakool, Podchanart,
Sirianant, Lalida,
Krautwald, Stefan,
Linkermann, Andreas ,
Schreiber, Rainer and
Kunzelmann, Karl
(2017)
Ca2+ signals, cell membrane disintegration, and activation of TMEM16F during necroptosis.
Cellular and Molecular Life Sciences 74 (1), pp. 173-181.
Fulltext not available.
Wanitchakool, Podchanart,
Ousingsawat, Jiraporn,
Sirianant, Lalida,
Cabrita, Inês,
Faria, Diana,
Schreiber, Rainer and
Kunzelmann, Karl
(2017)
Cellular defects by deletion of ANO10 are due to deregulated local calcium signaling.
Cellular Signalling 30, pp. 41-49.
Fulltext not available.
Benedetto, Roberta,
Ousingsawat, Jiraporn,
Wanitchakool, Podchanart,
Zhang, Yong,
Holtzman, Michael J.,
Amaral, Margarida ,
Rock, Jason R.,
Schreiber, Rainer and
Kunzelmann, Karl
(2017)
Epithelial Chloride Transport by CFTR Requires TMEM16A.
Scientific Reports 7 (1).
Fulltext not available.
Schreiber, Rainer,
Ousingsawat, Jiraporn ,
Wanitchakool, Podchanart,
Sirianant, Lalida,
Benedetto, Roberta,
Reiss, Karina and
Kunzelmann, Karl
(2017)
Regulation of TMEM16A/ANO1 and TMEM16F/ANO6 ion currents and phospholipid scrambling by Ca2+and plasma membrane lipid.
The Journal of Physiology 596 (2), pp. 217-229.
Fulltext not available.
Sirianant, Lalida,
Ousingsawat, Jiraporn,
Wanitchakool, Podchanart,
Schreiber, Rainer and
Kunzelmann, Karl
(2016)
Cellular volume regulation by anoctamin 6: Ca2+, phospholipase A2 and osmosensing.
Pflügers Archiv - European Journal of Physiology 468 (2), pp. 335-349.
Fulltext not available.
Wanitchakool, Podchanart,
Ousingsawat, Jiraporn,
Sirianant, Lalida,
MacAulay, Nanna ,
Schreiber, Rainer and
Kunzelmann, Karl
(2016)
Cl− channels in apoptosis.
European Biophysics Journal 45 (7), pp. 599-610.
Fulltext not available.
Kraus, Andre,
Schley, Gunnar,
Kunzelmann, Karl,
Schreiber, Rainer,
Peters, Dorien J. M.,
Stadler, Ruth,
Eckardt, Kai-Uwe and
Buchholz, Bjoern
(2016)
Glucose promotes secretion-dependent renal cyst growth.
Journal of Molecular Medicine 94 (1), pp. 107-117.
Fulltext not available.
Sirianant, Lalida,
Wanitchakool, Podchanart,
Ousingsawat, Jiraporn,
Benedetto, Roberta,
Zormpa, Anna,
Cabrita, Ines,
Schreiber, Rainer and
Kunzelmann, Karl
(2016)
Non-essential contribution of LRRC8A to volume regulation.
Pflügers Archiv - European Journal of Physiology 468 (5), pp. 805-816.
Fulltext not available.
Sommer, Anselm,
Kordowski, Felix,
Büch, Joscha,
Maretzky, Thorsten ,
Evers, Astrid,
Andrä, Jörg,
Düsterhöft, Stefan,
Michalek, Matthias,
Lorenzen, Inken,
Somasundaram, Prasath,
Tholey, Andreas ,
Sönnichsen, Frank D.,
Kunzelmann, Karl,
Heinbockel, Lena,
Nehls, Christian,
Gutsmann, Thomas,
Grötzinger, Joachim,
Bhakdi, Sucharit and
Reiss, Karina
(2016)
Phosphatidylserine exposure is required for ADAM17 sheddase function.
Nature Communications 7 (1).
Fulltext not available.
Benedetto, Roberta,
Sirianant, Lalida,
Pankonien, Ines ,
Wanitchakool, Podchanart,
Ousingsawat, Jiraporn,
Cabrita, Ines,
Schreiber, Rainer,
Amaral, Margarida and
Kunzelmann, Karl
(2016)
Relationship between TMEM16A/anoctamin 1 and LRRC8A.
Pflügers Archiv - European Journal of Physiology 468 (10), pp. 1751-1763.
Fulltext not available.
Mattheij, Nadine J. A.,
Braun, Attila,
Kruchten, Roger,
Castoldi, Elisabetta,
Pircher, Joachim,
Baaten, Constance C. F. M. J.,
Wülling, Manuela,
Kuijpers, Marijke J. E.,
Köhler, Ralf,
Poole, Alastair W. ,
Schreiber, Rainer,
Vortkamp, Andrea,
Collins, Peter W.,
Nieswandt, Bernhard,
Kunzelmann, Karl,
Cosemans, Judith M. E. M and
Heemskerk, Johan W. M.
(2016)
Survival protein anoctamin‐6 controls multiple platelet responses including phospholipid scrambling, swelling, and protein cleavage.
The FASEB Journal 30 (2), pp. 727-737.
Fulltext not available.
Guoxing, Liu,
Guilai, Liu,
Hong, Chen,
Borst, Oliver,
Gawaz, Meinrad,
Vortkamp, Andrea,
Schreiber, Rainer ,
Kunzelmann, Karl and
Lang, Florian
(2015)
Involvement of Ca2+ Activated Cl- Channel Ano6 in Platelet Activation and Apoptosis.
Cellular Physiology and Biochemistry 37 (5), pp. 1934-1944.
Szteyn, K.,
Schmid, Evi,
Nurbaeva, M.K.,
Wang, Wenting,
Münzer, P.,
Kunzelmann, Karl ,
Lang, Florian and
Shumilina, E.
(2012)
Expression and Functional Significance of the Ca2+-Activated Cl- Channel ANO6 in Dendritic Cells.
Cellular Physiology and Biochemistry 30, pp. 13196-1332.
Thesis of the University of Regensburg
This list was generated on Mon Sep 9 23:26:48 2024 CEST.