Number of items at this level: 184.
Article
Ousingsawat, Jiraporn 
,
Talbi, Khaoula,
Gómez-Martín, Hilario,
Koy, Anne,
Fernández-Jaén, Alberto,
Tekgül, Hasan,
Serdaroğlu, Esra,
Ortigoza-Escobar, Juan Darío,
Schreiber, Rainer 
and
Kunzelmann, Karl
(2025)
Dystonia caused by ANO3 variants is due to attenuated Ca2+ influx by ORAI1.
BMC Medicine 23 (1).
Ousingsawat, Jiraporn 
,
Centeio, Raquel,
Reyne, Nicole,
McCarron, Alexandra,
Cmielewski, Patricia,
Schreiber, Rainer 
,
diStefano, Gabriella,
Römermann, Dorothee,
Seidler, Ursula,
Donnelley, Martin and
Kunzelmann, Karl 
(2024)
Inhibition of mucus secretion by niclosamide and benzbromarone in airways and intestine.
Scientific Reports 14 (1).
Kunzelmann, Karl 
,
Ousingsawat, Jiraporn 
,
Kraus, Andre,
Park, Julien H.,
Marquardt, Thorsten,
Schreiber, Rainer 
and
Buchholz, Björn
(2023)
Pathogenic Relationships in Cystic Fibrosis and Renal Diseases: CFTR, SLC26A9 and Anoctamins.
International Journal of Molecular Sciences 24 (17), p. 13278.
Di Palma, Michael 
,
Catalano, Myriam,
Serpe, Carmela,
De Luca, Mariassunta,
Monaco, Lucia,
Kunzelmann, Karl,
Limatola, Cristina,
Conti, Fiorenzo 
and
Fattorini, Giorgia
(2023)
Lipopolysaccharide augments microglial GABA uptake by increasing GABA transporter‐1 trafficking and bestrophin‐1 expression.
Glia 71 (11), pp. 2527-2540.
Fulltext not available.
Lin, JinHeng,
Gettings, Sean M. 
,
Talbi, Khaoula,
Schreiber, Rainer,
Taggart, Michael J.,
Preller, Matthias 
,
Kunzelmann, Karl,
Althaus, Mike 
and
Gray, Michael A.
(2023)
Pharmacological inhibitors of the cystic fibrosis transmembrane conductance regulator exert off-target effects on epithelial cation channels.
Pflügers Archiv - European Journal of Physiology 475 (2), pp. 167-179.
Fulltext not available.
Kunzelmann, Karl 
,
Centeio, Raquel,
Ousingsawat, Jiraporn,
Talbi, Khaoula,
Seidler, Ursula and
Schreiber, Rainer
(2023)
SLC26A9 in airways and intestine: secretion or absorption?
Channels 17 (1).
Fulltext not available.
Salari, Azam 
,
Xiu, Renjie,
Amiri, Mahdi 
,
Pallenberg, Sophia Theres,
Schreiber, Rainer 
,
Dittrich, Anna-Maria 
,
Tümmler, Burkhard,
Kunzelmann, Karl and
Seidler, Ursula 
(2023)
The Anion Channel TMEM16a/Ano1 Modulates CFTR Activity, but Does Not Function as an Apical Anion Channel in Colonic Epithelium from Cystic Fibrosis Patients and Healthy Individuals.
International Journal of Molecular Sciences 24 (18), p. 14214.
Fulltext not available.
Jo, Sungwoo,
Centeio, Raquel,
Park, Jinhong,
Ousingsawat, Jiraporn,
Jeon, Dong‐kyu,
Talbi, Khaoula,
Schreiber, Rainer,
Ryu, Kunhi,
Kahlenberg, Kristin,
Somoza, Veronika 
,
Delpiano, Livia 
,
Gray, Michael A.,
Amaral, Margarida D. 
,
Railean, Violeta,
Beekman, Jeffrey M.,
Rodenburg, Lisa W.,
Namkung, Wan and
Kunzelmann, Karl
(2022)
The SLC26A9 inhibitor S9‐A13 provides no evidence for a role of SLC26A9 in airway chloride secretion but suggests a contribution to regulation of ASL pH and gastric proton secretion.
The FASEB Journal 36 (11), e22534.
Ousingsawat, Jiraporn 
,
Centeio, Raquel,
Cabrita, Inês 
,
Talbi, Khaoula,
Zimmer, Oliver 
,
Graf, Moritz,
Göpferich, Achim 
,
Schreiber, Rainer 
and
Kunzelmann, Karl 
(2022)
Airway Delivery of Hydrogel-Encapsulated Niclosamide for the Treatment of Inflammatory Airway Disease.
International Journal of Molecular Sciences 23 (3), p. 1085.
Leitzke, Sinje,
Seidel, Jana,
Ahrens, Björn,
Schreiber, Rainer,
Kunzelmann, Karl,
Sperrhacke, Maria,
Bhakdi, Sucharit and
Reiss, Karina
(2022)
Influence of Anoctamin-4 and -9 on ADAM10 and ADAM17 Sheddase Function.
Membranes 12 (2), p. 123.
Fulltext not available.
Talbi, Khaoula,
Cabrita, Inês,
Kraus, Andre,
Hofmann, Sascha,
Skoczynski, Kathrin,
Kunzelmann, Karl 
,
Buchholz, Bjoern and
Schreiber, Rainer 
(2021)
The chloride channel CFTR is not required for cyst growth in an ADPKD mouse model.
The FASEB Journal 35 (10), pp. 1-12.
Kunzelmann, Karl 
,
Centeio, Raquel,
Ousingsawat, Jiraporn 
,
Cabrita, Inês 
,
Schreiber, Rainer 
,
Talbi, Khaoula,
Benedetto, Roberta,
Doušová, Tereza 
,
Verbeken, Eric K.,
De Boeck, Kris and
Cohen, Isaac
(2021)
Mucus Release and Airway Constriction by TMEM16A May Worsen Pathology in Inflammatory Lung Disease.
International Journal of Molecular Sciences 22 (7852), pp. 1-18.
Grosch, Melanie,
Brunner, Katrin,
Ilyaskin, Alexandr V. 
,
Schober, Michael,
Staudner, Tobias,
Schmied, Denise,
Stumpp, Tina,
Schmidt, Kerstin N.,
Madej, M. Gregor 
,
Pessoa, Thaissa D.,
Othmen, Helga,
Kubitza, Marion,
Osten, Larissa,
de Vries, Uwe,
Mair, Magdalena M. 
,
Somlo, Stefan,
Moser, Markus,
Kunzelmann, Karl,
Ziegler, Christine 
,
Haerteis, Silke,
Korbmacher, Christoph and
Witzgall, Ralph
(2021)
A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts.
Journal of Cell Science 134 (16).
Fulltext not available.
Pereira, Catarina 
,
Mazein, Alexander,
Farinha, Carlos M.,
Gray, Michael A.,
Kunzelmann, Karl,
Ostaszewski, Marek,
Balaur, Irina,
Amaral, Margarida D. 
and
Falcao, Andre O.
(2021)
CyFi-MAP: an interactive pathway-based resource for cystic fibrosis.
Scientific Reports 11 (1).
Fulltext not available.
Cabrita, Inês,
Benedetto, Roberta,
Wanitchakool, Podchanart,
Lerias, Joana,
Centeio, Raquel,
Ousingsawat, Jiraporn,
Schreiber, Rainer and
Kunzelmann, Karl
(2021)
TMEM16A Mediates Mucus Production in Human Airway Epithelial Cells.
American Journal of Respiratory Cell and Molecular Biology 64 (1), pp. 50-58.
Fulltext not available.
Berg, Peder 
,
Svendsen, Samuel L.,
Sorensen, Mads Vaarby 
,
Schreiber, Rainer,
Kunzelmann, Karl 
and
Leipziger, Jens 
(2021)
The molecular mechanism of CFTR‐ and secretin‐dependent renal bicarbonate excretion.
The Journal of Physiology 599 (12), pp. 3003-3011.
Fulltext not available.
Cabrita, Ines,
Kraus, Andre,
Scholz, Julia Katharina,
Skoczynski, Kathrin,
Schreiber, Rainer,
Kunzelmann, Karl 
and
Buchholz, Björn
(2020)
Cyst growth in ADPKD is prevented by pharmacological and genetic inhibition of TMEM16A in vivo.
Nature Communications 11, p. 4320.
Oliver, Paula M.,
Neubert, Patrick,
Homann, Arne,
Wendelborn, David,
Bär, Anna-Lorena 
,
Krampert, Luka 
,
Trum, Maximilian,
Schröder, Agnes,
Ebner, Stefan,
Weichselbaum, Andrea,
Schatz, Valentin,
Linz, Peter,
Veelken, Roland,
Schulte-Schrepping, Jonas 
,
Aschenbrenner, Anna C.,
Quast, Thomas,
Kurts, Christian,
Geisberger, Sabrina,
Kunzelmann, Karl,
Hammer, Karin,
Binger, Katrina J.,
Titze, Jens,
Müller, Dominik N.,
Kolanus, Waldemar 
,
Schultze, Joachim L.,
Wagner, Stefan and
Jantsch, Jonathan 
(2020)
NCX1 represents an ionic Na+ sensing mechanism in macrophages.
PLOS Biology 18 (6), e3000722.
Pinto, Madalena C. 
,
Schreiber, Rainer,
Lerias, Joana,
Ousingsawat, Jiraporn,
Duarte, Aires,
Amaral, Margarida 
and
Kunzelmann, Karl 
(2020)
Regulation of TMEM16A by CK2 and Its Role in Cellular Proliferation.
Cells 9 (5), p. 1138.
Centeio, Raquel,
Cabrita, Inês,
Benedetto, Roberta,
Talbi, Khaoula,
Ousingsawat, Jiraporn,
Schreiber, Rainer,
Sullivan, John K. 
and
Kunzelmann, Karl 
(2020)
Pharmacological Inhibition and Activation of the Ca2+ Activated Cl− Channel TMEM16A.
International Journal of Molecular Sciences 21 (7), p. 2557.
Silva, Iris A. L.,
Duarte, Aires,
Marson, Fernando A. L. 
,
Centeio, Raquel,
Doušová, Tereza,
Kunzelmann, Karl and
Amaral, Margarida D.
(2020)
Assessment of Distinct Electrophysiological Parameters in Rectal Biopsies for the Choice of the Best Diagnosis/Prognosis Biomarkers for Cystic Fibrosis.
Frontiers in Physiology 11.
Fulltext not available.
Ormel, Lasse,
Lauritzen, Knut H.,
Schreiber, Rainer,
Kunzelmann, Karl and
Gundersen, Vidar
(2020)
GABA, but Not Bestrophin-1, Is Localized in Astroglial Processes in the Mouse Hippocampus and the Cerebellum.
Frontiers in Molecular Neuroscience 13.
Fulltext not available.
Berg, Peder,
Svendsen, Samuel L.,
Sorensen, Mads V. 
,
Larsen, Casper K.,
Andersen, Jesper Frank,
Jensen-Fangel, Søren,
Jeppesen, Majbritt,
Schreiber, Rainer,
Cabrita, Ines,
Kunzelmann, Karl and
Leipziger, Jens
(2020)
Impaired Renal HCO3- Excretion in Cystic Fibrosis.
Journal of the American Society of Nephrology 31 (8), pp. 1711-1727.
Fulltext not available.
Sousa, Luis 
,
Pankonien, Ines 
,
Clarke, Luka A. 
,
Silva, Iris 
,
Kunzelmann, Karl 
and
Amaral, Margarida D. 
(2020)
KLF4 Acts as a wt-CFTR Suppressor through an AKT-Mediated Pathway.
Cells 9 (7), p. 1607.
Fulltext not available.
Silva, Iris A.L.,
Doušová, Tereza,
Ramalho, Sofia,
Centeio, Raquel,
Clarke, Luka A. 
,
Railean, Violeta,
Botelho, Hugo M.,
Holubová, Andrea,
Valášková, Iveta,
Yeh, Jiunn-Tyng,
Hwang, Tzyh-Chang,
Farinha, Carlos M.,
Kunzelmann, Karl and
Amaral, Margarida D. 
(2020)
Organoids as a personalized medicine tool for ultra-rare mutations in cystic fibrosis: The case of S955P and 1717-2A>G.
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1866 (11), p. 165905.
Fulltext not available.
Park, Julien H,
Ousingsawat, Jiraporn,
Cabrita, Inês,
Bettels, Ruth E,
Große-Onnebrink, Jörg,
Schmalstieg, Christian,
Biskup, Saskia,
Reunert, Janine,
Rust, Stephan,
Schreiber, Rainer,
Kunzelmann, Karl and
Marquardt, Thorsten
(2020)
TMEM16A deficiency: a potentially fatal neonatal disease resulting from impaired chloride currents.
Journal of Medical Genetics 58 (4), pp. 247-253.
Fulltext not available.
Benedetto, Roberta,
Centeio, Raquel,
Ousingsawat, Jiraporn,
Schreiber, Rainer,
Kunzelmann, Karl and
make_name_string expected hash reference 
(2020)
Transport properties in CFTR−/− knockout piglets suggest normal airway surface liquid pH and enhanced amiloride-sensitive Na+ absorption.
Pflügers Archiv - European Journal of Physiology 472, pp. 1507-1519.
Kunzelmann, Karl 
,
Centeio, Raquel,
Wanitchakool, Podchanart,
Cabrita, Inês,
Benedetto, Roberta,
Saha, Tultul,
Hoque, Kazi Mirajul and
Schreiber, Rainer 
(2019)
Control of Ion Transport by Tmem16a Expressed in Murine Intestine.
Frontiers in Physiology 10 (1262), pp. 1-10.
Bleibaum, Florian 
,
Sommer, Anselm,
Veit, Martin,
Rabe, Björn,
Andrä, Jörg,
Kunzelmann, Karl,
Nehls, Christian,
Correa, Wilmar,
Gutsmann, Thomas,
Grötzinger, Joachim,
Bhakdi, Sucharit,
Reiss, Karina and
Fu, Haian
(2019)
ADAM10 sheddase activation is controlled by cell membrane asymmetry.
Journal of Molecular Cell Biology 11 (11), pp. 979-993.
Fulltext not available.
Nagy, Magdolna,
van Geffen, Johanna P.,
Stegner, David 
,
Adams, David J.,
Braun, Attila,
de Witt, Susanne M.,
Elvers, Margitta,
Geer, Mitchell J. 
,
Kuijpers, Marijke J. E.,
Kunzelmann, Karl,
Mori, Jun,
Oury, Cécile,
Pircher, Joachim,
Pleines, Irina,
Poole, Alastair W.,
Senis, Yotis A.,
Verdoold, Remco,
Weber, Christian 
,
Nieswandt, Bernhard,
Heemskerk, Johan W. M. and
Baaten, Constance C. F. M. J.
(2019)
Comparative Analysis of Microfluidics Thrombus Formation in Multiple Genetically Modified Mice: Link to Thrombosis and Hemostasis.
Frontiers in Cardiovascular Medicine 6.
Fulltext not available.
Miner, Kent,
Labitzke, Katja,
Liu, Benxian,
Wang, Paul,
Henckels, Kathryn,
Gaida, Kevin,
Elliott, Robin,
Chen, Jian Jeffrey,
Liu, Longbin,
Leith, Anh,
Trueblood, Esther,
Hensley, Kelly,
Xia, Xing-Zhong,
Homann, Oliver,
Bennett, Brian,
Fiorino, Mike,
Whoriskey, John,
Yu, Gang,
Escobar, Sabine,
Wong, Min,
Born, Teresa L.,
Budelsky, Alison,
Comeau, Mike,
Smith, Dirk,
Phillips, Jonathan 
,
Johnston, James A.,
McGivern, Joseph G.,
Weikl, Kerstin,
Powers, David,
Kunzelmann, Karl,
Mohn, Deanna,
Hochheimer, Andreas and
Sullivan, John K.
(2019)
Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide Are Potent TMEM16A Antagonists That Fully Bronchodilate Airways.
Frontiers in Pharmacology 10.
Fulltext not available.
Schreiber, Rainer,
Buchholz, Björn,
Kraus, Andre,
Schley, Gunnar,
Scholz, Julia,
Ousingsawat, Jiraporn and
Kunzelmann, Karl
(2019)
Lipid Peroxidation Drives Renal Cyst Growth In Vitro through Activation of TMEM16A.
Journal of the American Society of Nephrology 30 (2), pp. 228-242.
Fulltext not available.
Benedetto, Roberta,
Ousingsawat, Jiraporn,
Cabrita, Inês,
Pinto, Madalena,
Lérias, Joana R.,
Wanitchakool, Podchanart,
Schreiber, Rainer and
Kunzelmann, Karl 
(2019)
Plasma membrane–localized TMEM16 proteins are indispensable for expression of CFTR.
Journal of Molecular Medicine 97 (5), pp. 711-722.
Fulltext not available.
Lérias, Joana R.,
Pinto, Madalena C. 
,
Botelho, Hugo M. 
,
Awatade, Nikhil T.,
Quaresma, Margarida C.,
Silva, Iris A.L. 
,
Wanitchakool, Podchanart,
Schreiber, Rainer,
Pepperkok, Rainer,
Kunzelmann, Karl and
Amaral, Margarida D. 
(2018)
A novel microscopy-based assay identifies extended synaptotagmin-1 (ESYT1) as a positive regulator of anoctamin 1 traffic.
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1865 (2), pp. 421-431.
Fulltext not available.
Veit, Martin,
Koyro, Katharina Isabelle,
Ahrens, Björn,
Bleibaum, Florian,
Munz, Martin,
Rövekamp, Hagen,
Andrä, Jörg,
Schreiber, Rainer,
Kunzelmann, Karl,
Sommer, Anselm,
Bhakdi, Sucharit and
Reiss, Karina
(2018)
Anoctamin-6 regulates ADAM sheddase function.
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1865 (11), pp. 1598-1610.
Fulltext not available.
Simões, Filipa,
Ousingsawat, Jiraporn,
Wanitchakool, Podchanart,
Fonseca, Ana 
,
Cabrita, Inês,
Benedetto, Roberta,
Schreiber, Rainer and
Kunzelmann, Karl
(2018)
CFTR supports cell death through ROS-dependent activation of TMEM16F (anoctamin 6).
Pflügers Archiv - European Journal of Physiology 470 (2), pp. 305-314.
Fulltext not available.
Lérias, Joana 
,
Pinto, Madalena 
,
Benedetto, Roberta,
Schreiber, Rainer,
Amaral, Margarida 
,
Aureli, Massimo 
and
Kunzelmann, Karl
(2018)
Compartmentalized crosstalk of CFTR and TMEM16A (ANO1) through EPAC1 and ADCY1.
Cellular Signalling 44, pp. 10-19.
Fulltext not available.
Kraus, Andre,
Peters, Dorien J.M.,
Klanke, Bernd,
Weidemann, Alexander,
Willam, Carsten,
Schley, Gunnar,
Kunzelmann, Karl,
Eckardt, Kai-Uwe and
Buchholz, Bjoern
(2018)
HIF-1α promotes cyst progression in a mouse model of autosomal dominant polycystic kidney disease.
Kidney International 94 (5), pp. 887-899.
Fulltext not available.
Schenk, Laura K.,
Buchholz, Bjoern,
Henke, Sebastian F.,
Michgehl, Ulf,
Daniel, Christoph 
,
Amann, Kerstin,
Kunzelmann, Karl and
Pavenstädt, Hermann
(2018)
Nephron-specific knockout of TMEM16A leads to reduced number of glomeruli and albuminuria.
American Journal of Physiology-Renal Physiology 315 (6), F1777-F1786.
Fulltext not available.
von Mässenhausen, Anne,
Tonnus, Wulf,
Himmerkus, Nina,
Parmentier, Simon,
Saleh, Danish,
Rodriguez, Diego,
Ousingsawat, Jiraporn,
Ang, Rosalind L.,
Weinberg, Joel M.,
Sanz, Ana B. 
,
Ortiz, Alberto,
Zierleyn, Adrian,
Becker, Jan Ulrich,
Baratte, Blandine,
Desban, Nathalie,
Bach, Stéphane,
Schiessl, Ina Maria 
,
Nogusa, Shoko,
Balachandran, Siddharth,
Anders, Hans Joachim,
Ting, Adrian T.,
Bleich, Markus 
,
Degterev, Alexei,
Kunzelmann, Karl,
Bornstein, Stefan R.,
Green, Douglas R. 
,
Hugo, Christian and
Linkermann, Andreas
(2018)
Phenytoin inhibits necroptosis.
Cell Death & Disease 9 (3).
Fulltext not available.
Hagmann, Henning,
Mangold, Nicole,
Rinschen, Markus M. 
,
Koenig, Tim,
Kunzelmann, Karl,
Schermer, Bernhard 
,
Benzing, Thomas and
Brinkkoetter, Paul T.
(2018)
Proline‐dependent and basophilic kinases phosphorylate human TRPC6 at serine 14 to control channel activity through increased membrane expression.
The FASEB Journal 32 (1), pp. 208-219.
Fulltext not available.
Schenk, Laura K.,
Ousingsawat, Jiraporn,
Skryabin, Boris V. 
,
Schreiber, Rainer,
Pavenstädt, Hermann and
Kunzelmann, Karl 
(2018)
Regulation and Function of TMEM16F in Renal Podocytes.
International Journal of Molecular Sciences 19, p. 1798.
Ousingsawat, Jiraporn,
Cabrita, Inês,
Wanitchakool, Podchanart,
Sirianant, Lalida,
Krautwald, Stefan,
Linkermann, Andreas 
,
Schreiber, Rainer and
Kunzelmann, Karl
(2017)
Ca2+ signals, cell membrane disintegration, and activation of TMEM16F during necroptosis.
Cellular and Molecular Life Sciences 74 (1), pp. 173-181.
Fulltext not available.
Wanitchakool, Podchanart,
Ousingsawat, Jiraporn,
Sirianant, Lalida,
Cabrita, Inês,
Faria, Diana,
Schreiber, Rainer and
Kunzelmann, Karl
(2017)
Cellular defects by deletion of ANO10 are due to deregulated local calcium signaling.
Cellular Signalling 30, pp. 41-49.
Fulltext not available.
Benedetto, Roberta,
Ousingsawat, Jiraporn,
Wanitchakool, Podchanart,
Zhang, Yong,
Holtzman, Michael J.,
Amaral, Margarida 
,
Rock, Jason R.,
Schreiber, Rainer and
Kunzelmann, Karl
(2017)
Epithelial Chloride Transport by CFTR Requires TMEM16A.
Scientific Reports 7 (1).
Fulltext not available.
Schreiber, Rainer,
Ousingsawat, Jiraporn 
,
Wanitchakool, Podchanart,
Sirianant, Lalida,
Benedetto, Roberta,
Reiss, Karina and
Kunzelmann, Karl 
(2017)
Regulation of TMEM16A/ANO1 and TMEM16F/ANO6 ion currents and phospholipid scrambling by Ca2+and plasma membrane lipid.
The Journal of Physiology 596 (2), pp. 217-229.
Fulltext not available.
Sirianant, Lalida,
Ousingsawat, Jiraporn,
Wanitchakool, Podchanart,
Schreiber, Rainer and
Kunzelmann, Karl
(2016)
Cellular volume regulation by anoctamin 6: Ca2+, phospholipase A2 and osmosensing.
Pflügers Archiv - European Journal of Physiology 468 (2), pp. 335-349.
Fulltext not available.
Wanitchakool, Podchanart,
Ousingsawat, Jiraporn,
Sirianant, Lalida,
MacAulay, Nanna 
,
Schreiber, Rainer and
Kunzelmann, Karl
(2016)
Cl− channels in apoptosis.
European Biophysics Journal 45 (7), pp. 599-610.
Fulltext not available.
Kraus, Andre,
Schley, Gunnar,
Kunzelmann, Karl,
Schreiber, Rainer,
Peters, Dorien J. M.,
Stadler, Ruth,
Eckardt, Kai-Uwe and
Buchholz, Bjoern
(2016)
Glucose promotes secretion-dependent renal cyst growth.
Journal of Molecular Medicine 94 (1), pp. 107-117.
Fulltext not available.
Sirianant, Lalida,
Wanitchakool, Podchanart,
Ousingsawat, Jiraporn,
Benedetto, Roberta,
Zormpa, Anna,
Cabrita, Ines,
Schreiber, Rainer and
Kunzelmann, Karl
(2016)
Non-essential contribution of LRRC8A to volume regulation.
Pflügers Archiv - European Journal of Physiology 468 (5), pp. 805-816.
Fulltext not available.
Sommer, Anselm,
Kordowski, Felix,
Büch, Joscha,
Maretzky, Thorsten 
,
Evers, Astrid,
Andrä, Jörg,
Düsterhöft, Stefan,
Michalek, Matthias,
Lorenzen, Inken,
Somasundaram, Prasath,
Tholey, Andreas 
,
Sönnichsen, Frank D.,
Kunzelmann, Karl,
Heinbockel, Lena,
Nehls, Christian,
Gutsmann, Thomas,
Grötzinger, Joachim,
Bhakdi, Sucharit and
Reiss, Karina
(2016)
Phosphatidylserine exposure is required for ADAM17 sheddase function.
Nature Communications 7 (1).
Fulltext not available.
Benedetto, Roberta,
Sirianant, Lalida,
Pankonien, Ines 
,
Wanitchakool, Podchanart,
Ousingsawat, Jiraporn,
Cabrita, Ines,
Schreiber, Rainer,
Amaral, Margarida 
and
Kunzelmann, Karl
(2016)
Relationship between TMEM16A/anoctamin 1 and LRRC8A.
Pflügers Archiv - European Journal of Physiology 468 (10), pp. 1751-1763.
Fulltext not available.
Mattheij, Nadine J. A.,
Braun, Attila,
Kruchten, Roger,
Castoldi, Elisabetta,
Pircher, Joachim,
Baaten, Constance C. F. M. J.,
Wülling, Manuela,
Kuijpers, Marijke J. E.,
Köhler, Ralf,
Poole, Alastair W. 
,
Schreiber, Rainer,
Vortkamp, Andrea,
Collins, Peter W.,
Nieswandt, Bernhard,
Kunzelmann, Karl,
Cosemans, Judith M. E. M and
Heemskerk, Johan W. M.
(2016)
Survival protein anoctamin‐6 controls multiple platelet responses including phospholipid scrambling, swelling, and protein cleavage.
The FASEB Journal 30 (2), pp. 727-737.
Fulltext not available.
Guoxing, Liu,
Guilai, Liu,
Hong, Chen,
Borst, Oliver,
Gawaz, Meinrad,
Vortkamp, Andrea,
Schreiber, Rainer 
,
Kunzelmann, Karl 
and
Lang, Florian
(2015)
Involvement of Ca2+ Activated Cl- Channel Ano6 in Platelet Activation and Apoptosis.
Cellular Physiology and Biochemistry 37 (5), pp. 1934-1944.
Forschbach, V,
Goppelt-Struebe, M,
Kunzelmann, K,
Schreiber, R,
Piedagnel, R,
Kraus, A,
Eckardt, K-U and
Buchholz, B
(2015)
Anoctamin 6 is localized in the primary cilium of renal tubular cells and is involved in apoptosis-dependent cyst lumen formation.
Cell Death & Disease 6 (10), e1899-e1899.
Fulltext not available.
Ousingsawat, Jiraporn,
Wanitchakool, Podchanart,
Kmit, Arthur,
Romao, Ana M.,
Jantarajit, Walailak,
Schreiber, Rainer and
Kunzelmann, Karl
(2015)
Anoctamin 6 mediates effects essential for innate immunity downstream of P2X7 receptors in macrophages.
Nature Communications 6 (1).
Fulltext not available.
Ousingsawat, Jiraporn,
Wanitchakool, Podchanart,
Schreiber, Rainer,
Wuelling, Manuela,
Vortkamp, Andrea and
Kunzelmann, Karl
(2015)
Anoctamin-6 Controls Bone Mineralization by Activating the Calcium Transporter NCX1.
Journal of Biological Chemistry 290 (10), pp. 6270-6280.
Fulltext not available.
Schreiber, Rainer,
Faria, Diana,
Skryabin, Boris V.,
Wanitchakool, Podchanart,
Rock, Jason R. and
Kunzelmann, Karl
(2015)
Anoctamins support calcium-dependent chloride secretion by facilitating calcium signaling in adult mouse intestine.
Pflügers Archiv - European Journal of Physiology 467 (6), pp. 1203-1213.
Fulltext not available.
Botelho, Hugo M. 
,
Uliyakina, Inna 
,
Awatade, Nikhil T. 
,
Proença, Maria C.,
Tischer, Christian,
Sirianant, Lalida,
Kunzelmann, Karl,
Pepperkok, Rainer and
Amaral, Margarida D. 
(2015)
Protein Traffic Disorders: an Effective High-Throughput Fluorescence Microscopy Pipeline for Drug Discovery.
Scientific Reports 5 (1).
Fulltext not available.
Schurek, Eva-Maria,
Völker, Linus A.,
Tax, Judit,
Lamkemeyer, Tobias,
Rinschen, Markus M.,
Ungrue, Denise,
Kratz, John E.,
Sirianant, Lalida,
Kunzelmann, Karl,
Chalfie, Martin,
Schermer, Bernhard 
,
Benzing, Thomas and
Höhne, Martin
(2014)
A Disease-causing Mutation Illuminates the Protein Membrane Topology of the Kidney-expressed Prohibitin Homology (PHB) Domain Protein Podocin.
Journal of Biological Chemistry 289 (16), pp. 11262-11271.
Fulltext not available.
Buchholz, Bjoern,
Faria, Diana 
,
Schley, Gunnar,
Schreiber, Rainer,
Eckardt, Kai-Uwe and
Kunzelmann, Karl 
(2014)
Anoctamin 1 induces calcium-activated chloride secretion and proliferation of renal cyst–forming epithelial cells.
Kidney International 85 (5), pp. 1058-1067.
Fulltext not available.
Buchholz, Bjoern,
Schley, Gunnar,
Faria, Diana,
Kroening, Sven,
Willam, Carsten,
Schreiber, Rainer,
Klanke, Bernd,
Burzlaff, Nicolai 
,
Jantsch, Jonathan,
Kunzelmann, Karl and
Eckardt, Kai-Uwe
(2014)
Hypoxia-Inducible Factor-1α Causes Renal Cyst Expansion through Calcium-Activated Chloride Secretion.
Journal of the American Society of Nephrology 25 (3), pp. 465-474.
Fulltext not available.
Faria, Diana,
Rock, Jason R.,
Romao, Ana M.,
Schweda, Frank,
Bandulik, Sascha,
Witzgall, Ralph 
,
Schlatter, Eberhard,
Heitzmann, Dirk,
Pavenstädt, Hermann,
Herrmann, Edwin,
Kunzelmann, Karl and
Schreiber, Rainer
(2014)
The calcium-activated chloride channel Anoctamin 1 contributes to the regulation of renal function.
Kidney International 85 (6), pp. 1369-1381.
Fulltext not available.
Tosoni, Kendra,
Stobbart, Michelle,
Cassidy, Diane M.,
Venerando, Andrea,
Pagano, Mario A. 
,
Luz, Simão,
Amaral, Margarida D. 
,
Kunzelmann, Karl 
,
Pinna, Lorenzo A. 
,
Farinha, Carlos M. 
and
Mehta, Anil
(2013)
CFTR mutations altering CFTR fragmentation.
Biochemical Journal 449 (1), pp. 295-305.
Fulltext not available.
Kmit, A,
van Kruchten, R,
Ousingsawat, J,
Mattheij, N J A,
Senden-Gijsbers, B,
Heemskerk, J W M,
Schreiber, R,
Bevers, E M and
Kunzelmann, K 
(2013)
Calcium-activated and apoptotic phospholipid scrambling induced by Ano6 can occur independently of Ano6 ion currents.
Cell Death & Disease 4 (4), e611-e611.
Fulltext not available.
Tian, Yuemin,
Schreiber, Rainer,
Wanitchakool, Podchanart,
Kongsuphol, Patthara,
Sousa, Marisa,
Uliyakina, Inna 
,
Palma, Marta,
Faria, Diana 
,
Traynor‐Kaplan, Alexis E,
Fragata, José I 
,
Amaral, Margarida D 
and
Kunzelmann, Karl 
(2013)
Control of TMEM16A by INO‐4995 and other inositolphosphates.
British Journal of Pharmacology 168 (1), pp. 253-265.
Fulltext not available.
Servidoni, Maria F,
Sousa, Marisa,
Vinagre, Adriana M,
Cardoso, Silvia R,
Ribeiro, Maria A 
,
Meirelles, Luciana R,
de Carvalho, Rita B,
Kunzelmann, Karl 
,
Ribeiro, Antônio F 
,
Ribeiro, José D 
and
Amaral, Margarida D 
(2013)
Rectal forceps biopsy procedure in cystic fibrosis: technical aspects and patients perspective for clinical trials feasibility.
BMC Gastroenterology 13 (1).
Fulltext not available.
Rahmati, Negah,
Kunzelmann, Karl 
,
Xu, Jie,
Barone, Sharon,
Sirianant, Lalida,
De Zeeuw, Chris I. and
Soleimani, Manoocher
(2013)
Slc26a11 is prominently expressed in the brain and functions as a chloride channel: expression in Purkinje cells and stimulation of V H+-ATPase.
Pflügers Archiv - European Journal of Physiology 465 (11), pp. 1583-1597.
Fulltext not available.
Kunzelmann, Karl 
,
Tian, Yuemin,
Martins, Joana Raquel 
,
Faria, Diana 
,
Kongsuphol, Patthara,
Ousingsawat, Jiraporn,
Wolf, Luisa and
Schreiber, Rainer
(2012)
Airway epithelial cells—Functional links between CFTR and anoctamin dependent Cl− secretion.
The International Journal of Biochemistry & Cell Biology 44 (11), pp. 1897-1900.
Fulltext not available.
Lo, Anthony WI.,
Ruiz, Christian 
,
Martins, Joana Raquel,
Rudin, Florian,
Schneider, Sandra,
Dietsche, Tanja,
Fischer, Claude A. 
,
Tornillo, Luigi,
Terracciano, Luigi M.,
Schreiber, Rainer,
Bubendorf, Lukas 
and
Kunzelmann, Karl
(2012)
Enhanced Expression of ANO1 in Head and Neck Squamous Cell Carcinoma Causes Cell Migration and Correlates with Poor Prognosis.
PLoS ONE 7 (8), e43265.
Fulltext not available.
Szteyn, K.,
Schmid, Evi,
Nurbaeva, M.K.,
Wang, Wenting,
Münzer, P.,
Kunzelmann, Karl 
,
Lang, Florian and
Shumilina, E.
(2012)
Expression and Functional Significance of the Ca2+-Activated Cl- Channel ANO6 in Dendritic Cells.
Cellular Physiology and Biochemistry 30, pp. 13196-1332.
Kunzelmann, Karl 
,
Schreiber, Rainer,
Kmit, Arthur,
Jantarajit, Walailak,
Martins, Joana Raquel 
,
Faria, Diana 
,
Kongsuphol, Patthara,
Ousingsawat, Jiraporn and
Tian, Yuemin
(2012)
Expression and function of epithelial anoctamins.
Experimental Physiology 97 (2), pp. 184-192.
Fulltext not available.
Hartl, Dominik 
,
Sousa, Marisa,
Servidoni, Maria F.,
Vinagre, Adriana M. 
,
Ramalho, Anabela S.,
Bonadia, Luciana C.,
Felício, Verónica 
,
Ribeiro, Maria A. 
,
Uliyakina, Inna 
,
Marson, Fernando A.,
Kmit, Arthur,
Cardoso, Silvia R. 
,
Ribeiro, José D.,
Bertuzzo, Carmen S. 
,
Sousa, Lisete 
,
Kunzelmann, Karl 
,
Ribeiro, Antônio F. 
and
Amaral, Margarida D.
(2012)
Measurements of CFTR-Mediated Cl− Secretion in Human Rectal Biopsies Constitute a Robust Biomarker for Cystic Fibrosis Diagnosis and Prognosis.
PLoS ONE 7 (10), e47708.
Fulltext not available.
Faria, Diana 
,
Lentze, Nicolas,
Almaça, Joana 
,
Luz, Simão,
Alessio, Luisa,
Tian, Yuemin,
Martins, José Paulo 
,
Cruz, Pedro 
,
Schreiber, Rainer,
Rezwan, Mandana,
Farinha, Carlos Miguel 
,
Auerbach, Daniel,
Amaral, Margarida D. 
and
Kunzelmann, Karl 
(2012)
Regulation of ENaC biogenesis by the stress response protein SERP1.
Pflügers Archiv - European Journal of Physiology 463 (6), pp. 819-827.
Fulltext not available.
Deb, Sumitra,
Oeggerli, Martin,
Tian, Yuemin,
Ruiz, Christian,
Wijker, Barbara,
Sauter, Guido,
Obermann, Ellen,
Güth, Uwe 
,
Zlobec, Inti,
Sausbier, Matthias 
,
Kunzelmann, Karl and
Bubendorf, Lukas
(2012)
Role of KCNMA1 in Breast Cancer.
PLoS ONE 7 (8), e41664.
Fulltext not available.
Duvvuri, Umamaheswar,
Shiwarski, Daniel J. 
,
Xiao, Dong,
Bertrand, Carol,
Huang, Xin,
Edinger, Robert S.,
Rock, Jason R.,
Harfe, Brian D.,
Henson, Brian J.,
Kunzelmann, Karl 
,
Schreiber, Rainer,
Seethala, Raja S.,
Egloff, Ann Marie,
Chen, Xing,
Lui, Vivian W. 
,
Grandis, Jennifer R. and
Gollin, Susanne M. 
(2012)
TMEM16A Induces MAPK and Contributes Directly to Tumorigenesis and Cancer Progression.
Cancer Research 72 (13), pp. 3270-3281.
Fulltext not available.
Ruiz, Christian,
Zlobec, Inti,
Rudin, Florian,
Schneider, Sandra,
Rufle, Alex,
Fischer, Claude,
Tornillo, Luigi,
Terracciano, Luigi M.,
Kunzelmann, Karl and
Bubendorf, Lukas
(2011)
Abstract 1082: The amplification and overexpression of the calcium activated chloride channel TMEM16A (aka DOG1) has a prognostic role in patients with head and neck squamous cell carcinoma.
Cancer Research 71 (8_Supp), p. 1082.
Fulltext not available.
Martins, Joana Raquel 
,
Faria, Diana 
,
Kongsuphol, Patthara,
Reisch, Barbara,
Schreiber, Rainer and
Kunzelmann, Karl 
(2011)
Anoctamin 6 is an essential component of the outwardly rectifying chloride channel.
Proceedings of the National Academy of Sciences 108 (44), pp. 18168-18172.
Fulltext not available.
Kunzelmann, Karl 
,
Tian, Yuemin,
Martins, Joana Raquel 
,
Faria, Diana 
,
Kongsuphol, Patthara,
Ousingsawat, Jiraporn,
Thevenod, Frank,
Roussa, Eleni,
Rock, Jason and
Schreiber, Rainer
(2011)
Anoctamins.
Pflügers Archiv - European Journal of Physiology 462 (2), pp. 195-208.
Fulltext not available.
Tian, Yuemin,
Kongsuphol, Patthara,
Hug, Martin,
Ousingsawat, Jiraporn,
Witzgall, Ralph 
,
Schreiber, Rainer and
Kunzelmann, Karl 
(2011)
Calmodulin‐dependent activation of the epithelial calcium‐dependent chloride channel TMEM16A.
The FASEB Journal 25 (3), pp. 1058-1068.
Fulltext not available.
Luz, Simão,
Kongsuphol, Patthara,
Mendes, Ana Isabel,
Romeiras, Francisco,
Sousa, Marisa,
Schreiber, Rainer,
Matos, Paulo 
,
Jordan, Peter 
,
Mehta, Anil,
Amaral, Margarida D. 
,
Kunzelmann, Karl 
and
Farinha, Carlos M. 
(2011)
Contribution of Casein Kinase 2 and Spleen Tyrosine Kinase to CFTR Trafficking and Protein Kinase A-Induced Activity.
Molecular and Cellular Biology 31 (22), pp. 4392-4404.
Fulltext not available.
Faria, Diana 
,
Dahimène, Shehrazade,
Alessio, Luisa,
Scott-Ward, Toby,
Schreiber, Rainer,
Kunzelmann, Karl 
and
Amaral, Margarida D. 
(2011)
Effect of Annexin A5 on CFTR: regulated traffic or scaffolding?
Molecular Membrane Biology 28 (1), pp. 14-29.
Fulltext not available.
Martins, Joana Raquel 
,
Kongsuphol, Patthara,
Sammels, Eva,
Dahimène, Shehrazade,
AlDehni, Fadi,
Clarke, Luka Alexander 
,
Schreiber, Rainer,
de Smedt, Humbert,
Amaral, Margarida D. 
and
Kunzelmann, Karl 
(2011)
F508del-CFTR increases intracellular Ca2+ signaling that causes enhanced calcium-dependent Cl− conductance in cystic fibrosis.
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1812 (11), pp. 1385-1392.
Fulltext not available.
Kunzelmann, Karl 
,
Kongsuphol, Patthara,
Chootip, Krongkarn,
Toledo, Caio,
Martins, Joana R. 
,
Almaca, Joana 
,
Tian, Yuemin,
Witzgall, Ralph 
,
Ousingsawat, Jiraporn and
Schreiber, Rainer
(2011)
Role of the Ca2+-activated Cl- channels bestrophin and anoctamin in epithelial cells.
Biological Chemistry 392 (1-2).
Fulltext not available.
Ousingsawat, Jiraporn,
Mirza, Myriam,
Tian, Yuemin,
Roussa, Eleni,
Schreiber, Rainer,
Cook, David I. and
Kunzelmann, Karl 
(2011)
Rotavirus toxin NSP4 induces diarrhea by activation of TMEM16A and inhibition of Na+ absorption.
Pflügers Archiv - European Journal of Physiology 461 (5), pp. 579-589.
Fulltext not available.
Barro-Soria, René,
Aldehni, Fadi,
Almaça, Joana 
,
Witzgall, Ralph 
,
Schreiber, Rainer and
Kunzelmann, Karl 
(2010)
ER-localized bestrophin 1 activates Ca2+-dependent ion channels TMEM16A and SK4 possibly by acting as a counterion channel.
Pflügers Archiv - European Journal of Physiology 459 (3), pp. 485-497.
Fulltext not available.
Almaça, Joana 
,
Kongsuphol, Patthara,
Hieke, Bernhard,
Ousingsawat, Jiraporn,
Viollet, Benoit 
,
Schreiber, Rainer,
Amaral, Margarida D. 
and
Kunzelmann, Karl 
(2010)
Erratum to: AMPK controls epithelial Na+ channels through Nedd4-2 and causes an epithelial phenotype when mutated.
Pflügers Archiv - European Journal of Physiology 460 (6), pp. 1105-1106.
Fulltext not available.
Skals, Marianne,
Jensen, Uffe B. 
,
Ousingsawat, Jiraporn,
Kunzelmann, Karl 
,
Leipziger, Jens 
and
Praetorius, Helle A. 
(2010)
Escherichia coli α-Hemolysin Triggers Shrinkage of Erythrocytes via KCa3.1 and TMEM16A Channels with Subsequent Phosphatidylserine Exposure.
Journal of Biological Chemistry 285 (20), pp. 15557-15565.
Fulltext not available.
Schreiber, Rainer,
Uliyakina, Inna 
,
Kongsuphol, Patthara,
Warth, Richard 
,
Mirza, Myriam,
Martins, Joana R. 
and
Kunzelmann, Karl 
(2010)
Expression and Function of Epithelial Anoctamins.
Journal of Biological Chemistry 285 (10), pp. 7838-7845.
Fulltext not available.
Carota, I. 
,
Theilig, F.,
Oppermann, M.,
Kongsuphol, P.,
Rosenauer, A. 
,
Schreiber, R.,
Jensen, B. L.,
Walter, S.,
Kunzelmann, K. 
and
Castrop, H.
(2010)
Localization and functional characterization of the human NKCC2 isoforms.
Acta Physiologica 199 (3), pp. 327-338.
Fulltext not available.
Kongsuphol, Patthara,
Cassidy, Diane,
Romeiras, Francisco,
Schreiber, Rainer,
Mehta, Anil and
Kunzelmann, Karl 
(2010)
Metformin Treatment of Diabetes Mellitus Increases the Risk for Pancreatitis in Patients Bearing the CFTR-mutation S573C.
Cellular Physiology and Biochemistry 25 (4-5), pp. 389-396.
Fulltext not available.
Duning, Kerstin,
Rosenbusch, Deike,
Schlüter, Marc A.,
Tian, Yuemin,
Kunzelmann, Karl 
,
Meyer, Nina,
Schulze, Ulf,
Markoff, Arseni,
Pavenstädt, Hermann and
Weide, Thomas
(2010)
Polycystin-2 Activity Is Controlled by Transcriptional Coactivator with PDZ Binding Motif and PALS1-associated Tight Junction Protein.
Journal of Biological Chemistry 285 (44), pp. 33584-33588.
Fulltext not available.
Koehl, G E,
Spitzner, M,
Ousingsawat, J,
Schreiber, R,
Geissler, E K and
Kunzelmann, K 
(2010)
Rapamycin inhibits oncogenic intestinal ion channels and neoplasia in APCMin/+ mice.
Oncogene 29 (10), pp. 1553-1560.
Fulltext not available.
Almaça, Joana 
,
Kongsuphol, Patthara,
Hieke, Bernhard,
Ousingsawat, Jiraporn,
Viollet, Benoit 
,
Schreiber, Rainer,
Amaral, Margarida D. 
and
Kunzelmann, Karl 
(2009)
AMPK controls epithelial Na+ channels through Nedd4-2 and causes an epithelial phenotype when mutated.
Pflügers Archiv - European Journal of Physiology 458 (4), pp. 713-721.
Fulltext not available.
Rotte, Anand,
Bhandaru, Madhuri,
Föller, Michael,
Biswas, Raja,
Mack, Andreas F.,
Friedrich, Björn,
Rexhepaj, Rexhep,
Nasir, Omaima,
Ackermann, Teresa F.,
Boini, Krishna M.,
Kunzelmann, Karl 
,
Behrens, Jürgen and
Lang, Florian
(2009)
APC Sensitive Gastric Acid Secretion.
Cellular Physiology and Biochemistry 23 (1-3), pp. 133-142.
Fulltext not available.
Aldehni, Fadi,
Spitzner, Melanie,
Martins, Joana Raquel 
,
Barro-Soria, René,
Schreiber, Rainer and
Kunzelmann, Karl 
(2009)
Bestrophin 1 Promotes Epithelial-to-mesenchymal Transition of Renal Collecting Duct Cells.
Journal of the American Society of Nephrology 20 (7), pp. 1556-1564.
Fulltext not available.
Treharne, Kate J.,
Xu, Zhe,
Chen, Jeng-Haur,
Best, O. Giles 
,
Cassidy, Diane M.,
Gruenert, Dieter C.,
Hegyi, Péter,
Gray, Michael A.,
Sheppard, David N.,
Kunzelmann, Karl 
and
Mehta, Anil
(2009)
Inhibition of Protein Kinase CK2 Closes the CFTR Cl<sup>-</sup> Channel, but has no Effect on the Cystic Fibrosis Mutant ΔF508-CFTR.
Cellular Physiology and Biochemistry 24 (5-6), pp. 347-360.
Fulltext not available.
Ousingsawat, Jiraporn,
Martins, Joana R. 
,
Schreiber, Rainer,
Rock, Jason R.,
Harfe, Brian D. and
Kunzelmann, Karl 
(2009)
Loss of TMEM16A Causes a Defect in Epithelial Ca2+-dependent Chloride Transport.
Journal of Biological Chemistry 284 (42), pp. 28698-28703.
Fulltext not available.
Kongsuphol, Patthara,
Cassidy, Diane,
Hieke, Bernhard,
Treharne, Kate J.,
Schreiber, Rainer,
Mehta, Anil and
Kunzelmann, Karl 
(2009)
Mechanistic Insight into Control of CFTR by AMPK.
Journal of Biological Chemistry 284 (9), pp. 5645-5653.
Fulltext not available.
Kongsuphol, Patthara,
Hieke, Bernhard,
Ousingsawat, Jiraporn,
Almaca, Joana 
,
Viollet, Benoit 
,
Schreiber, Rainer and
Kunzelmann, Karl 
(2009)
Regulation of Cl− secretion by AMPK in vivo.
Pflügers Archiv - European Journal of Physiology 457 (5), pp. 1071-1078.
Fulltext not available.
Almaça, Joana 
,
Tian, Yuemin,
Aldehni, Fadi,
Ousingsawat, Jiraporn,
Kongsuphol, Patthara,
Rock, Jason R.,
Harfe, Brian D.,
Schreiber, Rainer and
Kunzelmann, Karl 
(2009)
TMEM16 Proteins Produce Volume-regulated Chloride Currents That Are Reduced in Mice Lacking TMEM16A.
Journal of Biological Chemistry 284 (42), pp. 28571-28578.
Fulltext not available.
Illek, Beate,
Maurisse, Rosalie,
Wahler, Logan,
Kunzelmann, Karl 
,
Fischer, Horst and
Gruenert, Dieter
(2008)
Cl Transport in Complemented CF Bronchial Epithelial Cells Correlates with CFTR mRNA Expression Levels.
Cellular Physiology and Biochemistry 22 (1-4), 057-068.
Fulltext not available.
Grangeia, Ana 
,
Barro-Soria, René,
Carvalho, Filipa 
,
Damas, Ana,
Maurício, Ana 
,
Kunzelmann, Karl 
,
Barros, Alberto 
and
Sousa, Mário 
(2008)
Molecular and Functional Characterization of CBAVD-Causing Mutations Located in CFTR Nucleotide-Binding Domains.
Cellular Physiology and Biochemistry 22 (1-4), 079-092.
Fulltext not available.
Bachhuber, Tanja,
Almaça, Joana 
,
Aldehni, Fadi,
Mehta, Anil,
Amaral, Margarida D. 
,
Schreiber, Rainer and
Kunzelmann, Karl 
(2008)
Regulation of the Epithelial Na+ Channel by the Protein Kinase CK2.
Journal of Biological Chemistry 283 (19), pp. 13225-13232.
Fulltext not available.
Schreiber, Rainer,
Sorria, René Barro,
Milenkovic, Vladimir,
Spitzner, Melanie,
Hieke, Bernhard and
Kunzelmann, Karl
(2007)
ATP induced Ca 2+ activated Cl − conductance is dependent on VMD2 (bestrophin‐1) expression.
The FASEB Journal 21 (6).
Fulltext not available.
Puntheeranurak, Supaporn,
Schreiber, Rainer,
Spitzner, Melanie,
Ousingsawat, Jiraporn,
Krishnamra, Nateetip and
Kunzelmann, Karl 
(2007)
Control of Ion Transport in Mouse Proximal and Distal Colon by Prolactin.
Cellular Physiology and Biochemistry 19 (1-4), pp. 77-88.
Fulltext not available.
Ousingsawat, Jiraporn,
Spitzner, Melanie,
Puntheeranurak, Supaporn,
Terracciano, Luigi,
Tornillo, Luigi 
,
Bubendorf, Lukas,
Kunzelmann, Karl 
and
Schreiber, Rainer
(2007)
Expression of Voltage-Gated Potassium Channels in Human and Mouse Colonic Carcinoma.
Clinical Cancer Research 13 (3), pp. 824-831.
Fulltext not available.
Bloch, M,
Ousingsawat, J,
Simon, R,
Schraml, P,
Gasser, T C,
Mihatsch, M J,
Kunzelmann, K 
and
Bubendorf, L
(2007)
KCNMA1 gene amplification promotes tumor cell proliferation in human prostate cancer.
Oncogene 26 (17), pp. 2525-2534.
Fulltext not available.
Kunzelmann, Karl 
,
Scheidt, Kerstin,
Scharf, Birgit,
Ousingsawat, Jiraporn,
Schreiber, Rainer,
Wainwright, Brandon and
McMorran, Brendan
(2006)
Flagellin of Pseudomonas aeruginosa inhibits Na
transport in airway epithelia.
The FASEB Journal 20 (3), pp. 545-546.
Fulltext not available.
Sousa, Marisa,
Ousingsawat, Jiraporn,
Seitz, Roswitha,
Puntheeranurak, Supaporn,
Regalado, Ana 
,
Schmidt, André,
Grego, Tiago 
,
Jansakul, Chaweewan,
Amaral, Margarida D. 
,
Schreiber, Rainer and
Kunzelmann, Karl 
(2006)
An Extract from the Medicinal PlantPhyllanthus acidusand Its Isolated Compounds Induce Airway Chloride Secretion: A Potential Treatment for Cystic Fibrosis.
Molecular Pharmacology 71 (1), pp. 366-376.
Fulltext not available.
Stumpf, Astrid,
Almaca, Joana 
,
Kunzelmann, Karl 
,
Wenners-Epping, Kerstin,
Huber, Stephan,
Haberle, Johannes,
Falk, Sabine,
Duebbers, Angelika,
Walte, Mike,
Oberleithner, Hans and
Schillers, Hermann
(2006)
IADS, a Decomposition Product of DIDS Activates a Cation Conductance in <i>Xenopus</i> Oocytes and Human Erythrocytes: New Compound for the Diagnosis of Cystic Fibrosis.
Cellular Physiology and Biochemistry 18 (4-5), pp. 243-252.
Fulltext not available.
Huber, Tobias B.,
Schermer, Bernhard 
,
Müller, Roman Ulrich,
Höhne, Martin,
Bartram, Malte,
Calixto, Andrea,
Hagmann, Henning,
Reinhardt, Christian,
Koos, Fabienne,
Kunzelmann, Karl 
,
Shirokova, Elena,
Krautwurst, Dietmar,
Harteneck, Christian,
Simons, Matias 
,
Pavenstädt, Hermann,
Kerjaschki, Dontscho,
Thiele, Christoph,
Walz, Gerd,
Chalfie, Martin and
Benzing, Thomas
(2006)
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels.
Proceedings of the National Academy of Sciences 103 (46), pp. 17079-17086.
Fulltext not available.
da Paula, Ana,
Ramalho, Anabela 
,
Farinha, Carlos 
,
Cheung, Judy,
Maurisse, Rosalie,
Gruenert, Dieter,
Ousingsawat, Jiraporn,
Kunzelmann, Karl 
and
Amaral, Margarida 
(2005)
Characterization of Novel Airway Submucosal Gland Cell Models for Cystic Fibrosis.
Cellular Physiology and Biochemistry 15 (6), pp. 251-262.
Fulltext not available.
Bachhuber, Tanja,
König, Jens,
Voelcker, Thilo,
Mürle, Bettina,
Schreiber, Rainer and
Kunzelmann, Karl 
(2005)
Cl– Interference with the Epithelial Na+ Channel ENaC.
Journal of Biological Chemistry 280 (36), pp. 31587-31594.
Fulltext not available.
Kunzelmann, Karl 
,
Sun, Jane,
Markovich, Daniel,
König, Jens,
Mürle, Bettina,
Mall, Marcus and
Schreiber, Rainer
(2005)
Control of ion transport in mammalian airways by protease activated receptors type 2 (PAR‐2).
The FASEB Journal 19 (8), pp. 969-970.
Fulltext not available.
Mendes, Filipa 
,
Wakefield, John,
Bachhuber, Tanja,
Barroso, Margarida 
,
Bebok, Zsuzsa,
Penque, Deborah 
,
Kunzelmann, Karl 
and
Amaral, Margarida D. 
(2005)
Establishment and Characterization of a Novel Polarized MDCK Epithelial Cellular Model for CFTR Studies.
Cellular Physiology and Biochemistry 16 (4-6), pp. 281-290.
Fulltext not available.
Kunzelmann, K. 
,
Bachhuber, T.,
Regeer, R.,
Markovich, D.,
Sun, J. and
Schreiber, R.
(2005)
Purinergic inhibition of the epithelial Na+transport via hydrolysis of PIP2.
The FASEB Journal 19 (1), pp. 142-143.
Fulltext not available.
Hirtz, Stephanie,
Gonska, Tanja,
Seydewitz, Hans H.,
Thomas, Jörg,
Greiner, Peter,
Kuehr, Joachim,
Brandis, Matthias,
Eichler, Irmgard,
Rocha, Herculano,
Lopes, Ana—Isabel,
Barreto, Celeste,
Ramalho, Anabela 
,
Amaral, Margarida D. 
,
Kunzelmann, Karl 
and
Mall, Marcus
(2004)
CFTR Cl− channel function in native human colon correlates with the genotype and phenotype in cystic fibrosis.
Gastroenterology 127 (4), pp. 1085-1095.
Fulltext not available.
Mall, Marcus,
Kreda, Silvia M.,
Mengos, April,
Jensen, Timothy J.,
Hirtz, Stephanie,
Seydewitz, Hans H.,
Yankaskas, James,
Kunzelmann, Karl 
,
Riordan, John R. and
Boucher, Richard C.
(2004)
The ΔF508 mutation results in loss of CFTR function and mature protein in native human colon.
Gastroenterology 126 (1), pp. 32-41.
Fulltext not available.
Schreiber, R.,
K�nig, J.,
Sun, J.,
Markovich, D. and
Kunzelmann, K. 
(2003)
Effects of Purinergic Stimulation, CFTR and Osmotic Stress on Amiloride-sensitive Na + Transport in Epithelia and Xenopus Oocytes.
Journal of Membrane Biology 192 (2), pp. 101-110.
Fulltext not available.
Thesis of the University of Regensburg
This list was generated on Sat May 17 17:28:00 2025 CEST.