Bibliography of the Universität Regensburg

University of Regensburg (169)
- Chemistry and Pharmacy (169)
  - Institute of Pharmacy (169)
    - Pharmaceutical/Medicinal Chemistry I (Prof. Elz) (169)

Group by: Date | Creators | Item type | No Grouping

Number of items at this level: 169.

Wirth, Lukas (2025) Neue Bisarylmethanon-Derivate als FLT3-Inhibitoren und „Proteolysis targeting chimeras“ (PROTACs) – Synthese und biologische Testung. PhD, Universität Regensburg.

Mönnich, Denise

(2025) Characterization of Monomers and Heteromers of the Dopamine and Histamine Receptor Families Using Bioluminescence- and Radioactivity-Based Techniques. PhD, Universität Regensburg.

Sellmer, Andreas, Able, Marina, Spiekermann, Karsten, Reinecke, Maria, Kuster, Bernhard, Utpatel, Kirsten

, Wirth, Lukas, Pongratz, Herwig, Plank, Nicole, Koch, Pierre

, Elz, Sigurd, Fischer, Amrei, Tizazu, Belay, Fiebig, Heinz-Herbert, Dove, Stefan and Mahboobi, Siavosh

(2025) Novel water-soluble and highly efficient dual type I/II next generation inhibitors of FMS-like tyrosine kinase 3 (FLT3). European Journal of Medicinal Chemistry 296, p. 117849.

Lier, Constantin, Kees, Frieder

, Witowski, Andrea, Rahmel, Tim, Pockes, Steffen

and Dorn, Christoph

(2025) Simultaneous determination of ceftazidime and avibactam in patients by isocratic ion-pair liquid chromatography with photometric detection. Journal of Chromatography Open 7, p. 100212.

Nagl, Martin (2024) Synthesis and pharmacological characterization of bivalent and fluorescent ligands to detect receptor dimerization for the D2-H3 heteromer. PhD, Universität Regensburg.

Rosier, Niklas (2024) Synthesis and pharmacological characterization of bivalent ligands for the D1-H3 receptor heteromer and fluorescent ligands for the D1 and H3 receptors. PhD, Universität Regensburg.

Scheuerer, Simon (2024) Selektive HDAC6-Inhibitoren und „Proteolysis Targeting Chimeras“ (PROTACs): Synthese und biologische Testung. PhD, Universität Regensburg.

Scheuerer, Simon, Motlova, Lucia, Schäker-Hübner, Linda, Sellmer, Andreas, Feller, Felix, Ertl, Fabian J., Koch, Pierre

, Hansen, Finn K., Barinka, Cyril and Mahboobi, Siavosh

(2024) Biological and structural investigation of tetrahydro-β-carboline-based selective HDAC6 inhibitors with improved stability. European Journal of Medicinal Chemistry 276, p. 116676.

Bresinsky, Merlin Niklas

(2024) Development and Biological Evaluation of Selective Ligands and Pharmacological Tools Targeting Caspase-2, Histamine H₂ Receptors, and orphan GPR3 for the Treatment of Neurodegenerative Diseases. PhD, Universität Regensburg.

Nagl, Martin, Moennich, Denise, Rosier, Niklas

, Schihada, Hannes, Sirbu, Alexei, Konar, Nergis, Reyes-Resina, Irene, Navarro, Gemma, Franco, Rafael, Kolb, Peter, Annibale, Paolo and Pockes, Steffen

(2023) Fluorescent Tools for the Imaging of Dopamine D2‐Like Receptors. ChemBioChem.

Rosier, Niklas

, Moennich, Denise, Nagl, Martin, Schihada, Hannes, Sirbu, Alexei, Konar, Nergis, Reyes-Resina, Irene, Navarro, Gemma, Franco, Rafael, Kolb, Peter, Annibale, Paolo and Pockes, Steffen

(2023) Shedding Light on the D1‐Like Receptors: A Fluorescence‐Based Toolbox for Visualization of the D1 and D5 Receptors. ChemBioChem.

Cuellar, Matthew E., Yang, Mu

, Karavadhi, Surendra, Zhang, Ya-Qin, Zhu, Hu, Sun, Hongmao, Shen, Min, Hall, Matthew D., Patnaik, Samarjit, Ashe, Karen H., Walters, Michael A.

and Pockes, Steffen

(2023) An electrophilic fragment screening for the development of small molecules targeting caspase-2. European Journal of Medicinal Chemistry 259, p. 115632. Fulltext not available.

Jacob, Hannes, Braekow, Pauline, Hofmann, Britt, Kirchhefer, Uwe, Forster, Lisa, Mönnich, Denise, Humphrys, Laura J., Pockes, Steffen, Neumann, Joachim and Gergs, Ulrich (2023) Ergometrine stimulates histamine H2 receptors in the isolated human atrium. Naunyn-Schmiedeberg's Archives of Pharmacology 396 (12), pp. 3809-3822. Fulltext not available.

Pockes, Steffen

, Walters, Michael A.

and Ashe, Karen H. (2023) Targeting caspase-2 interactions with tau in Alzheimer's disease and related dementias. Translational Research 254, pp. 34-40. Fulltext not available.

Winkler, René

, Mägdefrau, Ann-Sophie, Piskor, Eva-Maria, Kleemann, Markus, Beyer, Mandy, Linke, Kevin, Hansen, Lisa, Schaffer, Anna-Maria

, Hoffmann, Marina E.

, Poepsel, Simon

, Heyd, Florian, Beli, Petra, Möröy, Tarik, Mahboobi, Siavosh, Krämer, Oliver H. and Kosan, Christian (2022) Targeting the MYC interaction network in B-cell lymphoma via histone deacetylase 6 inhibition. Oncogene 41 (40), pp. 4560-4572.

Pilsl, Bernadette (2022) Neue Indolderivate als FLT3-Inhibitoren und chimäre FLT3- und HDAC-Inhibitoren: Synthese und biologische Testung. PhD, Universität Regensburg.

Singh, Gurpreet, Liu, Peng, Yao, Katherine R., Strasser, Jessica M., Hlynialuk, Chris, Leinonen-Wright, Kailee, Teravskis, Peter J., Choquette, Jessica M., Ikramuddin, Junaid, Bresinsky, Merlin, Nelson, Kathryn M., Liao, Dezhi, Ashe, Karen H., Walters, Michael A. and Pockes, Steffen (2022) Caspase-2 Inhibitor Blocks Tau Truncation and Restores Excitatory Neurotransmission in Neurons Modeling FTDP-17 Tauopathy. ACS Chemical Neuroscience 13 (10), pp. 1549-1557. Fulltext not available.

Beyer, Mandy, Henninger, Sven J., Haehnel, Patricia S., Mustafa, Al-Hassan M.

, Gurdal, Ece

, Schubert, Bastian, Christmann, Markus, Sellmer, Andreas

, Mahboobi, Siavosh, Drube, Sebastian, Sippl, Wolfgang, Kindler, Thomas and Krämer, Oliver H. (2022) Identification of a highly efficient dual type I/II FMS-like tyrosine kinase inhibitor that disrupts the growth of leukemic cells. Cell Chemical Biology 29 (3), 398-411.e4. Fulltext not available.

Szczepańska, Katarzyna, Podlewska, Sabina, Dichiara, Maria, Gentile, Davide, Patamia, Vincenzo, Rosier, Niklas, Mönnich, Denise, Ruiz Cantero, Ma Carmen, Karcz, Tadeusz, Łażewska, Dorota, Siwek, Agata, Pockes, Steffen, Cobos, Enrique J., Marrazzo, Agostino, Stark, Holger, Rescifina, Antonio, Bojarski, Andrzej J., Amata, Emanuele and Kieć-Kononowicz, Katarzyna (2022) Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H3 and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties. ACS Chemical Neuroscience 13 (1), pp. 1-15. Fulltext not available.

Wachholz, Vanessa, Mustafa, Al-Hassan M., Zeyn, Yanira, Henninger, Sven J., Beyer, Mandy, Dzulko, Melanie, Piée-Staffa, Andrea, Brachetti, Christina, Haehnel, Patricia S., Sellmer, Andreas, Mahboobi, Siavosh, Kindler, Thomas, Brenner, Walburgis, Nikolova, Teodora and Krämer, Oliver H. (2021) Inhibitors of class I HDACs and of FLT3 combine synergistically against leukemia cells with mutant FLT3. Archives of Toxicology 96 (1), pp. 177-193.

Pockes, Steffen

and Tropmann, Katharina

(2021) Histamine H2 receptor radioligands: triumphs and challenges. Future Medicinal Chemistry 13 (12), pp. 1073-1081.

Grätz, Lukas, Laasfeld, Tõnis, Allikalt, Anni

, Gruber, Corinna G., Pegoli, Andrea, Tahk, Maris-Johanna, Tsernant, Mari-Liis, Keller, Max and Rinken, Ago (2021) BRET- and fluorescence anisotropy-based assays for real-time monitoring of ligand binding to M2 muscarinic acetylcholine receptors. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1868 (3), p. 118930. Fulltext not available.

Gergs, Ulrich, Büxel, Maren L., Bresinsky, Merlin, Kirchhefer, Uwe, Fehse, Charlotte, Höring, Carina, Hofmann, Britt, Marušáková, Margaréta, Čináková, Aneta, Schwarz, Rebecca, Pockes, Steffen

and Neumann, Joachim (2021) Cardiac Effects of Novel Histamine H2 Receptor Agonists. Journal of Pharmacology and Experimental Therapeutics 379 (3), pp. 223-234. Fulltext not available.

Szczepańska, Katarzyna

, Pockes, Steffen

, Podlewska, Sabina, Höring, Carina, Mika, Kamil, Latacz, Gniewomir, Bednarski, Marek, Siwek, Agata

, Karcz, Tadeusz, Nagl, Martin, Bresinsky, Merlin, Mönnich, Denise, Seibel, Ulla, Kuder, Kamil J.

, Kotańska, Magdalena, Stark, Holger, Elz, Sigurd and Kieć-Kononowicz, Katarzyna (2021) Structural modifications in the distal, regulatory region of histamine H3 receptor antagonists leading to the identification of a potent anti-obesity agent. European Journal of Medicinal Chemistry 213, p. 113041. Fulltext not available.

Naporra, Franziska Gertraud (2020) Synthese und pharmakologische Charakterisierung neuer trizyklischer Liganden am Histamin-H1/H4-Rezeptor. PhD, Universität Regensburg.

Grätz, Lukas, Tropmann, Katharina, Bresinsky, Merlin, Müller, Christoph, Bernhardt, Günther

and Pockes, Steffen (2020) NanoBRET binding assay for histamine H2 receptor ligands using live recombinant HEK293T cells. Scientific Reports 10, p. 13288.

Forster, Lisa

, Grätz, Lukas, Mönnich, Denise, Bernhardt, Günther and Pockes, Steffen (2020) A Split Luciferase Complementation Assay for the Quantification of β-Arrestin2 Recruitment to Dopamine D2-Like Receptors. International Journal of Molecular Sciences 21 (17), p. 6103.

Sellmer, Andreas, Pilsl, Bernadette, Beyer, Mandy, Pongratz, Herwig, Wirth, Lukas, Elz, Sigurd, Dove, Stefan, Henninger, Sven Julian, Spiekermann, Karsten, Polzer, Harald, Klaeger, Susan, Kuster, Bernhard, Böhmer, Frank D., Fiebig, Heinz-Herbert, Krämer, Oliver H. and Mahboobi, Siavosh (2020) A series of novel aryl-methanone derivatives as inhibitors of FMS-like tyrosine kinase 3 (FLT3) in FLT3-ITD-positive acute myeloid leukemia. European Journal of Medicinal Chemistry 193, p. 112232. Fulltext not available.

Schihada, Hannes

, Ma, Xiaoyuan, Zabel, Ulrike, Vischer, Henry F., Schulte, Gunnar

, Leurs, Rob, Pockes, Steffen

and Lohse, Martin J.

(2020) Development of a Conformational Histamine H3 Receptor Biosensor for the Synchronous Screening of Agonists and Inverse Agonists. ACS Sensors 5 (6), pp. 1734-1742. Fulltext not available.

Tropmann, Katharina, Höring, Carina

, Plank, Nicole and Pockes, Steffen

(2020) Discovery of a G Protein-Biased Radioligand for the Histamine H2 Receptor with Reversible Binding Properties. Journal of Medicinal Chemistry 63 (21), pp. 13090-13102. Fulltext not available.

Grünstein, Elisabeth (2019) Selektive HDAC6-Inhibitoren: Synthese und biologische Testung. PhD, Universität Regensburg.

Pockes, Steffen, Wifling, David

, Buschauer, Armin

and Elz, Sigurd (2019) Structure‐Activity Relationship of Hetarylpropylguanidines Aiming at the Development of Selective Histamine Receptor Ligands †. ChemistryOpen 8 (3), pp. 285-297.

Rustler, Karin

, Pockes, Steffen

and König, Burkhard

(2019) Light-Switchable Antagonists for the Histamine H1 Receptor at the Isolated Guinea Pig Ileum. ChemMedChem 14 (6), pp. 636-644. Fulltext not available.

Wiegrebe, Wolfgang (2019) Adam and Eve's Origin According to Islam: A Response to Daud Abdul-Fattah Batchelor. Theology and Science 17 (4), pp. 455-468. Fulltext not available.

Rustler, Karin

, Pockes, Steffen

and König, Burkhard

(2019) Cover Feature: Light‐Switchable Antagonists for the Histamine H 1 Receptor at the Isolated Guinea Pig Ileum (ChemMedChem 6/2019). ChemMedChem 14 (6), p. 614. Fulltext not available.

Grünstein, Elisabeth, Sellmer, Andreas and Mahboobi, Siavosh (2019) Enantioselective synthesis and biological investigation of tetrahydro‐β‐carboline‐based HDAC6 inhibitors with improved solubility. Archiv der Pharmazie 352 (6), p. 1900026. Fulltext not available.

Beyer, M., Romanski, A., Mustafa, Al-Hassan M. and Sellmer, Andreas (2019) HDAC3 is essential for Human Leukemic Cell Growth and the Expression of β-catenin, MYC, and WT1. Cancers 11, p. 1436.

Soliman, Beatrice, Wang, Ning, Zagotto, Giuseppe and Pockes, Steffen

(2019) Synthesis and biological evaluation of heteroalicyclic cyanoguanidines at histamine receptors. Archiv der Pharmazie 352 (9), p. 1900107. Fulltext not available.

Pockes, Steffen

, Wifling, David

, Keller, Max, Buschauer, Armin

and Elz, Sigurd (2018) Highly Potent, Stable, and Selective Dimeric Hetarylpropylguanidine-Type Histamine H2 Receptor Agonists. ACS Omega 2018 (3), pp. 2865-2882.

Pockes, Steffen (2018) Synthese und pharmakologische Charakterisierung von Heteroarylpropylguanidin-Derivaten an Histamin-Rezeptorsubtypen: Struktur-Wirkungsbeziehungen mono- und bivalenter Liganden. PhD, Universität Regensburg.

Leonhardt, Michel, Sellmer, Andreas

, Krämer, Oliver H., Dove, Stefan, Elz, Sigurd, Kraus, Birgit, Beyer, Mandy and Mahboobi, Siavosh (2018) Design and biological evaluation of tetrahydro-β-carboline derivatives as highly potent histone deacetylase 6 (HDAC6) inhibitors. European Journal of Medicinal Chemistry 152, pp. 329-357. Fulltext not available.

Ridinger, Johannes, Koeneke, Emily, Kolbinger, Fiona R., Koerholz, Katharina, Mahboobi, Siavosh, Hellweg, Lars, Gunkel, Nikolas, Miller, Aubry K., Peterziel, Heike, Schmezer, Peter, Hamacher-Brady, Anne

, Witt, Olaf and Oehme, Ina (2018) Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance. Scientific Reports 8 (1). Fulltext not available.

Pons, Miriam, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference

, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference, make_name_string expected hash reference and make_name_string expected hash reference (2018) Human platelet lysate as validated replacement for animal serum to assess chemosensitivity. ALTEX. Fulltext not available.

Stojanovic, N., Hassan, Z., Wirth, M., Wenzel, P., Beyer, M., Schäfer, C., Brand, P., Kroemer, A., Stauber, R. H., Schmid, R. M., Arlt, A., Sellmer, A., Mahboobi, S., Rad, R., Reichert, M., Saur, D., Krämer, O. H. and Schneider, G. (2017) HDAC1 and HDAC2 integrate the expression of p53 mutants in pancreatic cancer. Oncogene 36 (13), pp. 1804-1815. Fulltext not available.

Tsitsipatis, Dimitrios, Jayavelu, Ashok Kumar, Müller, Jörg P., Bauer, Reinhard, Schmidt-Arras, Dirk, Mahboobi, Siavosh, Schnöder, Tina M., Heidel, Florian and Böhmer, Frank D. (2017) Synergistic killing of FLT3ITD-positive AML cells by combined inhibition of tyrosine-kinase activity and N-glycosylation. Oncotarget 8 (16). Fulltext not available.

Sadek, Bassem, Khan, Nadia, Darras, Fouad H., Pockes, Steffen

and Decker, Michael (2016) The dual-acting AChE inhibitor and H3 receptor antagonist UW-MD-72 reverses amnesia induced by scopolamine or dizocilpine in passive avoidance paradigm in rats. Physiology & Behavior 165, pp. 383-391. Fulltext not available.

Naporra, Franziska, Gobleder, Susanne, Wittmann, Hans-Joachim, Spindler, Julia, Bodensteiner, Michael, Bernhardt, Günther, Hübner, Harald, Gmeiner, Peter, Elz, Sigurd and Strasser, Andrea (2016) Dibenzo[b,f][1,4]oxazepines and dibenzo[b,e]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H1R, H4R, 5-HT2AR and other selected GPCRs. Pharmacological Research 113, pp. 610-625. (In Press) Fulltext not available.

Gobleder, Susanne (2016) Synthesis and pharmacological characterization of new histamine H1-/H4-receptor ligands derived from the atypical antipsychotic drug Clozapine. PhD, Universität Regensburg.

Hammer, Sebastian, Gobleder, Susanne, Naporra, Franziska, Wittmann, Hans-Joachim, Elz, Sigurd, Heinrich, Markus

and Strasser, Andrea (2016) 2,4-Diaminopyrimidines as dual ligands at the histamine H1 and H4 receptor - H1/H4-receptor selectivity. Bioorganic & Medicinal Chemistry Letters 26, pp. 292-300. Fulltext not available.

Naporra, Franziska, Gobleder, Susanne, Wittmann, Hans-Joachim, Spindler, Julia, Bodensteiner, Michael, Bernhardt, Günther, Hübner, Harald, Gmeiner, Peter

, Elz, Sigurd and Strasser, Andrea (2016) Dibenzo[ b , f ][1,4]oxazepines and dibenzo[ b , e ]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H 1 R, H 4 R, 5-HT 2A R and other selected GPCRs. Pharmacological Research 113, pp. 610-625. Fulltext not available.

Helm, Klaus (2015) Synthese und funktionelle In-vitro-Pharmakologie neuer Liganden des 5-HT2A-Rezeptors aus der Klasse der Tryptamine. PhD, Universität Regensburg.

Baumeister, Paul, Erdmann, Daniela, Biselli, Sabrina, Kagermeier, Nicole, Elz, Sigurd, Bernhardt, Günther and Buschauer, Armin (2015) 3HUR-DE257: Development of a tritium-labeled squaramide-type selective histamine H2 receptor antagonist. ChemMedChem 10 (1), pp. 83-93. Fulltext not available.

Darras, Fouad, Pockes, Steffen, Huang, Guozheng

, Wehle, Sarah, Strasser, Andrea, Wittmann, Hans-Joachim, Nimczick, Martin, Sotriffer, Christoph and Decker, Michael (2014) Synthesis, biological evaluation, and computational studies of tri- and tetracyclic nitrogen-bridgehead compounds as potent dual-acting AChE inhibitors and hH3 receptor antagonists. ACS Chemical Neuroscience 5 (3), pp. 225-242. Fulltext not available.

Wager, Eva, Wittmann, Hans-Joachim, Elz, Sigurd and Strasser, Andrea (2014) Pharmacological profile of astemizole-derived compounds at the histamine H1 and H4 receptor - H1/H4 receptor selectivity. Naunyn-Schmiedeberg's Archives of Pharmacology 387, pp. 235-250. Fulltext not available.

Geyer, Roland, Igel, Patrick, Kaske, Melanie, Elz, Sigurd and Buschauer, Armin (2014) Synthesis, SAR and selectivity of 2-acyl- and 2-cyano-1-hetarylalkyl-guanidines at the four histamine receptor subtypes: a bioisosteric approach. MedChemComm 5 (1), pp. 72-81. Fulltext not available.

Sadek, Bassem, Alisch, Rudi, Buschauer, Armin and Elz, Sigurd (2013) Synthesis and dual histamine H1 and H2 receptor antagonist activity of cyanoguanidine derivatives. Molecules 18 (11), pp. 14186-14202.

Susanne Hopf, , Monika Bumel, , Michael Gruber,

, Thomas Bein, , Marcus Creutzenberg, , Bernhard Graf, and Michael Pawlik, (2013) The Effect of Perchlorate Medication on Point-of-Care Testing. Clinical Laboratory 59 (01+02/). Fulltext not available.

Eswayah, Asma Mohamed (2012) Neue Imidazol- und Indolderivate - Synthese und biologische in-vitro-Prüfungen. PhD, Universität Regensburg.

Birnkammer, Tobias, Spickenreither, Anja, Brunskole, Irena, Lopuch, Miroslaw, Kagermeier, Nicole, Bernhardt, Günther, Dove, Stefan, Seifert, Roland, Elz, Sigurd and Buschauer, Armin (2012) The bivalent ligand approach leads to highly potent and selective acylguanidine-type histamine H2 receptor agonists. Journal of Medicinal Chemistry 55 (3), pp. 1147-1160. Fulltext not available.

Strasser, Andrea and Wittmann, Hans-Joachim (2012) Binding of Ligands to GPCRs – How Valid is a Thermodynamic
Discrimination of Antagonists and Agonists? Journal of Physical Chemistry & Biophysics 2012.

Beckers, Thomas, Mahboobi, Siavosh, Sellmer, Andreas, Winkler, Matthias, Eichhorn, Emerich, Pongratz, Herwig, Maier, Thomas, Ciossek, Thomas, Baer, Thomas, Kelter, Gerhard, Fiebig, Heinz-Herbert and Schmidt, Mathias (2012) Chimerically designed HDAC- and tyrosine kinase inhibitors. A series of erlotinib hybrids as dual-selective inhibitors of EGFR, HER2 and histone deacetylases. MedChemComm 3 (7), p. 829. Fulltext not available.

Appl, Heidrun, Holzammer, Tobias, Dove, Stefan, Haen, Ekkehard, Strasser, Andrea and Seifert, Roland (2012) Interactions of recombinant human histamine H₁R, H₂R, H₃R, and H₄R receptors with 34 antidepressants and antipsychotics. Naunyn-Schmiedeberg's archives of pharmacology 385 (2), pp. 145-170. Fulltext not available.

Beckers, Thomas, Sellmer, Andreas, Eichhorn, Emerich, Pongratz, Herwig, Schächtele, Christoph, Totzke, Frank, Kelter, Gerhard, Krumbach, Rebekka, Fiebig, Heinz-Herbert, Böhmer, Frank-D. and Mahboobi, Siavosh (2012) Novel inhibitors of epidermal growth factor receptor: (4-(Arylamino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)(1H-indol-2-yl)methanones and (1H-indol-2-yl)(4-(phenylamino)thieno[2,3-d]pyrimidin-6-yl)methanones. Bioorganic & Medicinal Chemistry 20 (1), pp. 125-136. Fulltext not available.

Silva, Maria Elena, Heim, Ralf, Strasser, Andrea, Elz, Sigurd and Dove, Stefan (2011) Theoretical studies on the interaction of partial agonists with the 5-HT(2A) receptor. Journal of computer-aided molecular design 25 (1), pp. 51-66. Fulltext not available.

Pertz, Heinz, Lehmann, Jochen, Roth-Ehrang, René and Elz, Sigurd (2011) Effects of Ginger Constituents on the Gastrointestinal Tract: Role of Cholinergic M3and Serotonergic 5-HT3and 5-HT4Receptors. Planta Medica 77 (10), pp. 973-978. Fulltext not available.

Wagner, Eva, Wittmann, Hans-Joachim, Elz, Sigurd and Strasser, Andrea (2011) Mepyramine-JNJ7777120-hybrid compounds show high affinity to hH1R, but low affinity to hH4R. Bioorganic & Medicinal Chemistry Letters 21, pp. 6274-9280. Fulltext not available.

Wittmann, Hans-Joachim, Elz, Sigurd, Seifert, Roland and Strasser, Andrea (2011) Na-methylated phenylhistamines exhibit affinity to the hH4R - a pharmacological and molecular modelling study. Naunyn Schmiedeberg's Arch Pharmacol 384, pp. 287-299. Fulltext not available.

Ghorai, Prasanta, Kraus, Anja, Birnkammer, Tobias, Geyer, Roland, Bernhardt, Günther, Dove, Stefan, Seifert, Roland, Elz, Sigurd and Buschauer, Armin (2010) Chiral N(G)-acylated hetarylpropylguanidine-type histamine H2 receptor agonists do not show significant stereoselectivity. Bioorganic & Medicinal Chemistry Letters 20 (10), pp. 3173-3176. Fulltext not available.

Matzdorf, Thorsten (2010) 5-Carboxamidotryptamin-Derivate als Liganden für 5-HT7- und 5-HT2A-Rezeptoren: Synthese und In-vitro-Pharmakologie. PhD, Universität Regensburg.

Strasser, Andrea and Wittmann, Hans-Joachim (2010) 3D-QSAR CoMFA study to predict orientation of suprahistaprodifens and phenoprodifens in the binding-pocket of four histamine H1-receptor species. Molecular Informatics 29, pp. 333-341. Fulltext not available.

Uecker, Andrea, Sicker, Marit, Beckers, Thomas, Mahboobi, Siavosh, Hägerstrand, Daniel

, Östman, Arne and Böhmer, Frank-D. (2010) Chimeric tyrosine kinase-HDAC inhibitors as antiproliferative agents. Anti-Cancer Drugs 21 (8), pp. 759-765. Fulltext not available.

Schneider, Erich H., Schnell, David, Strasser, Andrea, Dove, Stefan and Seifert, Roland (2010) Impact of the DRY Motif and the Missing "Ionic Lock" on Constitutive Activity and G-Protein Coupling of the Human Histamine H-4 Receptor. Journal of Pharmacology and Experimental Therapeutics 333 (2), pp. 382-392. Fulltext not available.

Schneider, Erich

, Schnell, David, Strasser, Andrea, Dove, Stefan and Seifert, Roland (2010) Impact of the DRY motif and the missing "ionic lock" on constitutive activity and G-protein coupling of the human histamine H4 receptor. J Pharmacol Exp Ther : The journal of pharmacology and experimental therapeutics 333 (2), pp. 382-392. Fulltext not available.

Mahboobi, Siavosh, Sellmer, Andreas, Winkler, Matthias, Eichhorn, Emerich, Pongratz, Herwig, Ciossek, Thomas, Baer, Thomas, Maier, Thomas and Beckers, Thomas (2010) Novel Chimeric Histone Deacetylase Inhibitors: A Series of Lapatinib Hybrides as Potent Inhibitors of Epidermal Growth Factor Receptor (EGFR), Human Epidermal Growth Factor Receptor 2 (HER2), and Histone Deacetylase Activity. Journal of Medicinal Chemistry 53 (24), pp. 8546-8555. Fulltext not available.

Jandt, Enrico, Mutschke, Oliver, Mahboobi, Siavosh, Uecker, Andrea, Platz, Ronny, Berndt, Alexander, Böhmer, Frank-D., Figulla, Hans R. and Werner, Gerald S. (2010) Stent-based release of a selective PDGF-receptor blocker from the bis-indolylmethanon class inhibits restenosis in the rabbit animal model. Vascular Pharmacology 52 (1-2), pp. 55-62. Fulltext not available.

Schneider, Erich H.

, Strasser, Andrea, Thurmond, Robin L. and Seifert, Roland (2010) Structural Requirements for Inverse Agonism and Neutral Antagonism of Indole-, Benzimidazole-, and Thienopyrrole-Derived Histamine H4 Receptor Ligands. Journal of Pharmacology and Experimental Therapeutics 334 (2), pp. 513-521. Fulltext not available.

Prainer, Bianca-Cristine (2009) Tryptamin-Derivate als 5-HT4-Rezeptorliganden: Synthese und in-vitro-Pharmakologie. PhD, Universität Regensburg.

Jenning, Stefan (2009) Ondansetron-analoge 5-HT3-Rezeptorliganden: Synthese, Stereochemie und in-vitro-Pharmakologie. PhD, Universität Regensburg.

Igel, Patrick, Schneider, Erich

, Schnell, David, Elz, Sigurd, Seifert, Roland and Buschauer, Armin (2009) N(G)-Acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent. Journal of Medicinal Chemistry 52 (8), pp. 2623-2627. Fulltext not available.

Romagnoli, Romeo, Baraldi, Pier Giovanni, Carrion, Maria Dora

, Cruz-Lopez, Olga, Lopez Cara, Carlota, Basso, Giuseppe, Viola, Giampietro

, Khedr, Mohammed

, Balzarini, Jan, Mahboobi, Siavosh, Sellmer, Andreas, Brancale, Andrea

and Hamel, Ernest (2009) 2-Arylamino-4-Amino-5-Aroylthiazoles. “One-Pot” Synthesis and Biological Evaluation of a New Class of Inhibitors of Tubulin Polymerization. Journal of Medicinal Chemistry 52 (17), pp. 5551-5555. Fulltext not available.

Heidel, Florian, Lipka, Daniel B., Mirea, Fian K., Mahboobi, Siavosh, Grundler, Rebekka, Kancha, Rama K., Duyster, Justus, Naumann, Michael

, Huber, Christoph, Böhmer, Frank D. and Fischer, Thomas (2009) Bis(1H‐indol‐2‐yl)methanones are effective inhibitors of FLT3‐ITD tyrosine kinase and partially overcome resistance to PKC412A in vitro. British Journal of Haematology 144 (6), pp. 865-874. Fulltext not available.

Wittmann, Hans-Joachim, Seifert, Roland and Strasser, Andrea (2009) Contribution of binding enthalpy and entropy to affinity of antagonist and agonist binding at human and guinea pig histamine H1-receptor. Molecular Pharmacology 76, pp. 25-37. Fulltext not available.

Mahboobi, Siavosh, Dove, Stefan, Sellmer, Andreas, Winkler, Matthias, Eichhorn, Emerich, Pongratz, Herwig, Ciossek, Thomas, Baer, Thomas, Maier, Thomas and Beckers, Thomas (2009) Design of chimeric histone deacetylase- and tyrosine kinase-inhibitors: a series of imatinib hybrides as potent inhibitors of wild-type and mutant BCR-ABL, PDGF-Rbeta, and histone deacetylases. Journal of medicinal chemistry 52 (8), pp. 2265-79. Fulltext not available.

Deml, Karl-Friedrich, Beermann, S, Neumann, Detlef

, Strasser, Andrea and Seifert, Roland (2009) Interactions of histamine H1-receptor agonists and antagonists with the human histamine H4-receptor. Mol Pharmacol : Molecular pharmacology 76 (5), pp. 1019-1030. Fulltext not available.

Strasser, Andrea, Wittmann, Hans-Joachim, Kunze, Marc, Elz, Sigurd and Seifert, Roland (2009) Molecular basis for the selective interaction of synthetic agonists with the human histamine H1-receptor compared with the guinea-pig H1-receptor. Mol Pharmacol : Molecular pharmacology 75, pp. 454-465. Fulltext not available.

Schumacher, Matthias (2008) Chirale Arylmethoxytryptamine als 5-HT2B-Rezeptoragonisten: Synthese, Analytik und in-vitro-Pharmakologie. PhD, Universität Regensburg.

Mahboobi, Siavosh, Eichhorn, Emerich, Winkler, Matthias, Sellmer, Andreas and Möllmann, Ute (2008) Antibacterial activity of a novel series of 3-bromo-4-(1H-3-indolyl)-2,5-dihydro-1H-2,5-pyrroledione derivatives – An extended structure–activity relationship study. European Journal of Medicinal Chemistry 43 (3), pp. 633-656. Fulltext not available.

Dove, Stefan, Seifert, Roland, Elz, Sigurd and Buschauer, Armin (2008) Frontiers in medicinal chemistry in Regensburg. ChemMedChem 3 (8), pp. 1181-1184. Fulltext not available.

Mahboobi, Siavosh, Sellmer, Andreas, Eswayah, Asma, Elz, Sigurd, Uecker, Andrea and Böhmer, Frank-D. (2008) Inhibition of PDGFR tyrosine kinase activity by a series of novel N-(3-(4-(pyridin-3-yl)-1H-imidazol-2-ylamino)phenyl)amides: a SAR study on the bioisosterism of pyrimidine and imidazole. European journal of medicinal chemistry 43 (7), pp. 1444-1453. Fulltext not available.

Kunze, Marc (2007) Histamin-H1-Rezeptoragonisten vom Suprahistaprodifen- und 2-Phenylhistamin-Typ und 2-substituierte Imidazolylpropan-Derivate als Liganden für H1/H2/H3/H4-Rezeptoren. Neue Synthesestrategien und pharmakologische Testung. PhD, Universität Regensburg.

Walbrun, Peter (2007) Repopulation genetisch veränderter Kupffer-Zellen und Evaluation deren Effekte in einem akuten hepatischen Schädigungsmodell. PhD, Universität Regensburg.

Striegl, Birgit (2007) Synthese und funktionelle in-vitro-Pharmakologie neuer Histamin-H1-Rezeptoragonisten aus der Suprahistaprodifen-Reihe. PhD, Universität Regensburg.

Mahboobi, Siavosh, Sellmer, Andreas, Höcher, Heymo, Garhammer, Christian, Pongratz, Herwig, Maier, Thomas, Ciossek, Thomas and Beckers, Thomas (2007) 2-Aroylindoles and 2-Aroylbenzofurans with N-Hydroxyacrylamide Substructures as a Novel Series of Rationally Designed Histone Deacetylase Inhibitors. Journal of Medicinal Chemistry 50 (18), pp. 4405-4418. Fulltext not available.

Strasser, Andrea and Wittmann, Hans-Joachim (2007) Analysis of the activation mechanism of the guinea-pig histamine H1-receptor. J Comput Aided Mol Des : Journal of computer aided molecular design 21, pp. 499-509. Fulltext not available.

Mahboobi, Siavosh, Uecker, A., Cénac, C., Sellmer, A., Eichhorn, E., Elz, Sigurd, Böhmer, F.-D. and Dove, Stefan (2007) Inhibition of FLT3 and PDGFR tyrosine kinase activity by bis(benzo[b]furan-2-yl)methanones. Bioorganic & medicinal chemistry 15 (5), pp. 2187-2197. Fulltext not available.

Mahboobi, Siavosh, Uecker, Andrea, Cénac, Christophe, Sellmer, Andreas, Eichhorn, Emerich, Elz, Sigurd, Böhmer, Frank-D. and Dove, Stefan (2007) Inhibition of FLT3 and PDGFR tyrosine kinase activity by bis(benzo[b]furan-2-yl)methanones. Bioorganic & Medicinal Chemistry 15 (5), pp. 2187-2197. Fulltext not available.

Bäumel, Monika (2006) Funktionelle Charakterisierung von p75TNF-Rezeptor-Isoformen. PhD, Universität Regensburg.

Xie, Sheng-Xue, Kraus, Anja, Ghorai, Prasanta, Ye, Qi-Zhuang, Elz, Sigurd, Buschauer, Armin and Seifert, Roland (2006) N1-(3-Cyclohexylbutanoyl)-N2-[3-(1H-imidazol-4-
yl)propyl]guanidine (UR-AK57), a Potent Partial Agonist for the Human Histamine H1- and H2- Receptors. Journal of Pharmacology and Experimental Therapeutics 317 (3), pp. 1262-1268. Fulltext restricted.

Patil, Rameshwar, Elz, Sigurd and Reiser, Oliver

(2006) Side-chain modified analogues of histaprodifen: Asymmetric synthesis and histamine H₁-receptor activity. Bioorg. Med. Chem. Lett. 16 (3), pp. 672-676. Fulltext not available.

Mahboobi, Siavosh, Eichhorn, Emerich, Popp, Alfred, Sellmer, Andreas, Elz, Sigurd and Möllmann, Ute (2006) 3-Bromo-4-(1H-3-indolyl)-2,5-dihydro-1H-2,5-pyrroledione derivatives as new lead compounds for antibacterially active substances. European Journal of Medicinal Chemistry 41 (2), pp. 176-191. Fulltext not available.

Guse, C., Koennings, S., Maschke, A., Hacker, M.

, Becker, C., Schreiner, S., Blunk, T., Spruss, T. and Goepferich, A.

(2006) Biocompatibility and erosion behavior of implants made of triglycerides and blends with cholesterol and phospholipids. International Journal of Pharmaceutics 314 (2), pp. 153-160. Fulltext not available.

Mahboobi, Siavosh, Uecker, Andrea, Sellmer, Andreas, Cénac, Christophe, Höcher, Heymo, Pongratz, Herwig, Eichhorn, Emerich, Hufsky, Harald, Trümpler, Antje, Sicker, Marit, Heidel, Florian, Fischer, Thomas, Stocking, Carol, Elz, Sigurd, Böhmer, Frank-D. and Dove, Stefan (2006) Novel Bis(1H-indol-2-yl)methanones as Potent Inhibitors of FLT3 and Platelet-Derived Growth Factor Receptor Tyrosine Kinase. Journal of Medicinal Chemistry 49 (11), pp. 3101-3115. Fulltext not available.

Mahboobi, Siavosh, Uecker, A., Sellmer, A., Cénac, C., Höcher, H., Pongratz, H., Hufsky, H., Trümpler, A., Sicker, M., Heidel, F., Fischer, T., Stocking, C., Elz, Sigurd, Böhmer, F.-D. and Dove, Stefan (2006) Novel bis-(1H-indol-2-yl)-methanones as potent inhibitors of FLT3 and platelet-derived growth factor receptor tyrosine kinase. Journal of Medicinal Chemistry 49 (11), pp. 3101-3115. Fulltext not available.

Sterns, Theobald (2005) Serum-Zytokinspiegel und Empfindlichkeit für Super-Infektionen im Maus-Sepsismodell. PhD, Universität Regensburg.

Scherübl, Christoph (2005) Charakterisierung einer neuen Isoform des humanen p75TNF-Rezeptors. PhD, Universität Regensburg.

Fryčák, Petr, Zdráhal, Zbyněk, Ulrichová, Jitka

, Wiegrebe, Wolfgang and Lemr, Karel

(2005) Evidence of covalent interaction of fumaric acid esters with sulfhydryl groups in peptides. Journal of Mass Spectrometry 40 (10), pp. 1309-1318. Fulltext not available.

Mahboobi, Siavosh, Sellmer, Andreas, Eichhorn, Emerich, Beckers, Thomas, Fiebig, Heinz-Herbert and Kelter, Gerhard (2005) Synthesis and cytotoxic activity of 2-acyl-1H-indole-4,7-diones on human cancer cell lines. European Journal of Medicinal Chemistry 40 (1), pp. 85-92. Fulltext not available.

Jirovsky, David and Wiegrebe, Wolfgang (2004) HPLC-Analysis of Fumarates in Biological Matrices. Monatshefte f�r Chemie/Chemical Monthly 135 (12), pp. 1563-1568. Fulltext not available.

Pertz, Heinz, Elz, Sigurd and Schunack, Walter (2004) Structure-Activity Relationships of Histamine H1-Receptor Agonists. Mini-Reviews in Medicinal Chemistry 4 (9), pp. 935-940. Fulltext not available.

Dove, Stefan, Elz, Sigurd, Seifert, Roland and Buschauer, Armin (2004) Structure-Activity Relationships of Histamine H2 Receptor Ligands+. Mini-Reviews in Medicinal Chemistry 4 (9), pp. 941-954. Fulltext not available.

Dove, Stefan, Elz, Sigurd, Seifert, Roland and Buschauer, Armin (2004) Structure-Activity Relationships of Histamine H_2 Receptor Ligands,. Mini-Rev. Med. Chem. 4 (9), pp. 941-954. Fulltext not available.

Mahboobi, Siavosh, Sellmer, Andreas, Burgemeister, Thomas, Lyssenko, Alexei and Schollmeyer, Dieter (2004) Synthesis of Naturally Occurring Pyrazine and Imidazole Alkaloids from Botryllus LeachiRID=?a?ID=?a? Dedicated to Prof. G . Märkl on the occasion of his 75 th birthday. Monatshefte f�r Chemie / Chemical Monthly 135 (3), pp. 333-342. Fulltext not available.

Welsh, Michael, Welsh, Charlotte, Ekman, Maria, Dixelius, Johan, Hägerkvist, Robert, Anneren, Cecilia, Åkerblom, Björn, Mahboobi, Siavosh, Chandrasekharan, Subhashini and Liu, Edison T. (2004) The tyrosine kinase FRK/RAK participates in cytokine-induced islet cell cytotoxicity. Biochemical Journal 382 (1), pp. 261-268. Fulltext not available.

Sadek, B., Elz, S., Pertz, H.H., Stark, H.

and Schunack, W. (2004) Unexpected partial H1-receptor agonism of imidazole-type histamine H3-receptor antagonists lacking a basic side chain. Inflammation Research 53 (S2). Fulltext not available.

Li, Liantao, Kracht, Julia, Peng, Shiqi, Bernhardt, Günther, Elz, Sigurd and Buschauer, Armin (2003) Synthesis and pharmacological activity of fluorescent histamine H2 receptor antagonists related to potentidine,. Bioorganic & Medicinal Chemistry Letters 13 (10), 0960-894. Fulltext not available.

Böhmer, F. D., Karagyozov, L., Uecker, A., Serve, H., Botzki, A., Mahboobi, Siavosh and Dove, Stefan (2003) A single amino acid exchange inverts susceptibility of related receptor tyrosine kinases for the ATP-site inhibitor STI-571. The Journal of Biological Chemistry 278 (7), pp. 5148-5155. Fulltext not available.

Iwasa, Kinuko, Kuribayashi, Ayako, Sugiura, Makiko, Moriyasu, Masataka, Lee, Dong-Ung and Wiegrebe, Wolfgang (2003) LC–NMR and LC–MS analysis of 2,3,10,11-oxygenated protoberberine metabolites in Corydalis cell cultures. Phytochemistry 64 (7), pp. 1229-1238. Fulltext not available.

Seifert, Roland, Wenzel-Seifert, Katharina, Bürckstümmer, Tilmann, Pertz, Heinz H., Schunack, Walter, Dove, Stefan, Buschauer, Armin and Elz, Sigurd (2003) Multiple differences in agonist and antagonist pharmacology between human and guinea pig histamine H1-receptor,. Journal of Pharmacology and Experimental Therapeutics 305, pp. 1104-1115. Fulltext not available.

Menghin, Sonja, Pertz, Heinz H., Kramer, Kai, Seifert, Roland, Schunack, Walter and Elz, Sigurd (2003) Nα-Imidazolylalkyl and Pyridylalkyl Derivatives of Histaprodifen: Synthesis and in Vitro Evaluation of Highly Potent Histamine H1-Receptor Agonists. Journal of Medicinal Chemistry 46 (25), pp. 5458-5470. Fulltext not available.

Govoni, Marinella, Bakker, Remko A., van de Wetering, Ineke, Smit, Martine J., Menge, Wiro M. B. P., Timmerman, Henk, Elz, Sigurd, Schunack, Walter and Leurs, Rob (2003) Synthesis and Pharmacological Identification of Neutral Histamine H1-Receptor Antagonists. Journal of Medicinal Chemistry 46 (26), pp. 5812-5824. Fulltext not available.

Teller, S, Krämer, D, Böhmer, S-A, Tse, KF, Small, D, Mahboobi, S, Wallrapp, C, Beckers, T, Kratz-Albers, K, Schwäble, J, Serve, H and Böhmer, F-D (2002) Bis(1H-2-indolyl)-1-methanones as inhibitors of the hematopoietic tyrosine kinase Flt3. Leukemia 16 (8), pp. 1528-1534. Fulltext not available.

Mahboobi, Siavosh, Teller, Steffen, Pongratz, Herwig, Hufsky, Harald, Sellmer, Andreas, Botzki, Alexander

, Uecker, Andrea, Beckers, Thomas, Baasner, Silke, Schächtele, Christoph, Überall, Florian, Kassack, Matthias U., Dove, Stefan and Böhmer, Frank-D. (2002) Bis(1H-2-indolyl)methanones as a Novel Class of Inhibitors of the Platelet-Derived Growth Factor Receptor Kinase. Journal of Medicinal Chemistry 45 (5), pp. 1002-1018. Fulltext not available.

Mahboobi, Siavosh, Teller, S., Pongratz, H., Hufsky, H., Sellmer, A., Botzki, Alexander, Uecker, A., Beckers, T., Baasner, S., Schächtele, C., Überall, F., Kassack, M. U., Dove, Stefan and Böhmer, F.-D. (2002) Bis(1H-2-indolyl)methanones as a novel class of inhibitors of the platelet-derived growth factor receptor kinase. Journal of Medicinal Chemistry 45 (5), pp. 1002-1018. Fulltext not available.

El-Subbagh, Hussein, Wittig, Thomas, Decker, Michael, Elz, Sigurd, Nieger, Martin

and Lehmann, Jochen (2002) Dopamine/Serotonin Receptor Ligands. Part IV [1]: Synthesis and Pharmacology of Novel 3-Benzazecines and 3-Benzazonines as Potential 5-HT2A and Dopamine Receptor Ligands. Archiv der Pharmazie 335 (9), pp. 443-448. Fulltext not available.

Letzel, Matthias C, Grützmacher, Hans-Friedrich, Fürst, Thomas, Mayer, Klaus K and Wiegrebe, Wolfgang (2002) Functional group migration in benzaldoxime-O-n-propyl ether radical cation. International Journal of Mass Spectrometry 217 (1-3), pp. 153-168. Fulltext not available.

Sasse, Astrid

, Ligneau, Xavier, Rouleau, Agnès, Elz, Sigurd, Ganellin, C. Robin, Arrang, Jean-Michel, Schwartz, Jean-Charles, Schunack, Walter and Stark, Holger

(2002) Influence of Bulky Substituents on Histamine H3Receptor Agonist/Antagonist Properties. Journal of Medicinal Chemistry 45 (18), pp. 4000-4010. Fulltext not available.

Graßmann, Sven, Sadek, Bassem, Ligneau, Xavier, Elz, Sigurd, Ganellin, C.Robin, Arrang, Jean-Michel, Schwartz, Jean-Charles, Stark, Holger

and Schunack, Walter (2002) Progress in the proxifan class: heterocyclic congeners as novel potent and selective histamine H3-receptor antagonists. European Journal of Pharmaceutical Sciences 15 (4), pp. 367-378. Fulltext not available.

Müller, Klaus, Breu, Klaus and Reindl, Hans (2001) 10-Phenylbutyryl-substituted anthracenones as inhibitors of keratinocyte growth and LTB4 biosynthesis. European Journal of Medicinal Chemistry 36 (2), pp. 179-184. Fulltext not available.

Müller, Klaus, Reindl, Hans and Breu, Klaus (2001) Antipsoriatic Anthrones with Modulated Redox Properties. 5. Potent Inhibition of Human Keratinocyte Growth, Induction of Keratinocyte Differentiation, and Reduced Membrane Damage by Novel 10-Arylacetyl-1,8-dihydroxy-9(10H)-anthracenones. Journal of Medicinal Chemistry 44 (5), pp. 814-821. Fulltext not available.

Müller, Klaus and Reindl, Hans (2001) Cornified Envelope Formation by Anthralin, Simple Analogues, and Related Anthracenones. Archiv der Pharmazie 334 (3), pp. 86-92. Fulltext not available.

de Martin, Rainer, Mrowietz, Ulrich, Wiegrebe, Wolfgang, Jirovsky, David, Loewe, Robert, Pillinger, Manuela

, Gröger, Marion, Holnthoner, Wolfgang, Wolff, Klaus and Petzelbauer, Peter (2001) Dimethylfumarate Inhibits Tumor-Necrosis-Factor-Induced CD62E Expression in an NF-κB-Dependent Manner. Journal of Investigative Dermatology 117 (6), pp. 1363-1368. Fulltext not available.

Müller, Klaus, Reindl, Hans and Breu, Klaus (2001) Heterocyclic substituted anthralin derivatives as inhibitors of keratinocyte growth and inducers of differentiation. Bioorganic & Medicinal Chemistry Letters 11 (1), pp. 47-50. Fulltext not available.

Iwasa, Kinuko, Moriyasu, Masataka, Yamori, Takao, Turuo, Takashi, Lee, Dong-Ung and Wiegrebe, Wolfgang (2001) In Vitro Cytotoxicity of the Protoberberine-Type Alkaloids. Journal of Natural Products 64 (7), pp. 896-898. Fulltext not available.

Jirovsky, David, Sellmer, Andreas, Guiswe, Pierre, Lemr, Karel

and Wiegrebe, Wolfgang (2001) On the Stereochemistry of Vincetene. Monatshefte fuer Chemie/Chemical Monthly 132 (6), pp. 765-768. Fulltext not available.

Vogelhuber, W., Rutunno, P., Magni, E., Gazzaniga, A.

, Spruss, Thilo, Bernhardt, Günther, Buschauer, Armin and Goepferich, Achim (2001) Programmable biodegradable implants. Journal of Controlled Release 73 (1), pp. 75-88. Fulltext not available.

Iwasa, Kinuko, Moriyasu, Masataka, Tachibana, Yoko, Kim, Hye-Sook, Wataya, Yusuke, Wiegrebe, Wolfgang, Bastow, Kenneth F, Cosentino, L.Mark, Kozuka, Mutsuo and Lee, Kuo-Hsiung (2001) Simple Isoquinoline and Benzylisoquinoline Alkaloids as Potential Antimicrobial, Antimalarial, Cytotoxic, and Anti-HIV Agents. Bioorganic & Medicinal Chemistry 9 (11), pp. 2871-2884. Fulltext not available.

Rostom, Sherif A. F., Farghaly, Ahmed M., Soliman, Farid S. G., El-Semary, Mona M., Elz, Sigurd and Lehmann, Jochen (2001) Synthesis and 5-HT2A Antagonist Activity of Derivatives of the Novel Heterocycles Indolo[3,2-d]pyrrolo[3,2-g]azecine and Benzo[d]pyrrolo[3,2-g]azecine compared to the Benz[d]indolo[2,3-g]azecine Derivative LE 300. Archiv der Pharmazie 334 (7), pp. 241-247. Fulltext not available.

Mahboobi, Siavosh, Pongratz, Herwig, Hufsky, Harald, Hockemeyer, Jörg, Frieser, Markus, Lyssenko, Alexei, Paper, Dietrich H., Bürgermeister, Jutta, Böhmer, Frank-D., Fiebig, Heinz-Herbert, Burger, Angelika M., Baasner, Silke and Beckers, Thomas (2001) Synthetic 2-Aroylindole Derivatives as a New Class of Potent Tubulin-Inhibitory, Antimitotic Agents. Journal of Medicinal Chemistry 44 (26), pp. 4535-4553. Fulltext not available.

Kumar KC, S (2000) Depsides as non-redox inhibitors of leukotriene B4 biosynthesis and HaCaT cell growth, 2. Novel analogues of obtusatic acid. European Journal of Medicinal Chemistry 35 (4), pp. 405-411. Fulltext not available.

Schlemmer, Richard, Spruß, Thilo, Bernhardt, Günther and Schönenberger, Helmut (2000) Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloroplatinum(II) act on the hormone-sensitive, murine breast cancer as a biological response modifier? Part 1: The MXT-M-3.2 breast cancer stimulates the growth of an identical second graft; [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]dichloroplat inum (II) inhibits this process. Archiv der Pharmazie 333 (2-3), pp. 69-71. Fulltext not available.

Kumar, Sunil, Ziereis, Klaus, Wiegrebe, Wolfgang and Müller, Klaus (2000) Medicinal plants from Nepal: evaluation as inhibitors of leukotriene biosynthesis. Journal of Ethnopharmacology 70 (3), pp. 191-195. Fulltext not available.

Teller, S (2000) Pyrrolo[3,4-c]-β-carboline-diones as a novel class of inhibitors of the platelet-derived growth factor receptor kinase. European Journal of Medicinal Chemistry 35 (4), pp. 413-427. Fulltext not available.

Mahboobi, Siavosh, Dechant, Irene, Reindl, Hans, Pongratz, Herwig, Popp, Alfred and Schollmeyer, Dieter (2000) Synthesis of bis(indolylmaleimide) macrocycles. Journal of Heterocyclic Chemistry 37 (2), pp. 307-329. Fulltext not available.

Mahboobi, Siavosh, Eluwa, Stella, Koller, Markus, Popp, Alfred and Schollmeyer, Dieter (2000) Synthesis of pyrrolo[3′,4′:2,3]azepino[4,5,6‐cd]indole‐8,10‐diones. Journal of Heterocyclic Chemistry 37 (5), pp. 1177-1185. Fulltext not available.

Mahboobi, Siavosh, Koller, Markus and Schollmeyer, Dieter (2000) Synthesis of the Racemates of the b-Carboline Alkaloid Chrysotricine and its Diastereomer. Monatshefte für Chemie/Chemical Monthly 131 (4), 0383-0392. Fulltext not available.

Mahboobi, Siavosh, Dove, Stefan, Kuhr, S. and Popp, A. (1999) Homo-arcyriaflavin: The synthesis of ring-expanded arcyriaflavin analogs. The Journal of Organic Chemistry 64 (22), pp. 8130-8137. Fulltext not available.

Mahboobi, Siavosh, Dove, Stefan, Kuhr, S. and Pongratz, Herwig (1999) Synthesis of arcyriarubine regioisomers by Pd(0)-catalysis or via lithiated indole derivatives - conformational analysis by semiempirical and X-ray methods. Pharmazie 54 (11), pp. 820-827. Fulltext not available.

Mayer, Klaus K., Dove, Stefan, Pongratz, Herwig, Ertan, M. and Wiegrebe, Wolfgang (1998) Electron impact induced fragmentation of 4-aryl-4,6,7,8-tetrahydro-1H,3H-quinazolinone-2,5-diones. Heterocycles 48 (6), pp. 1169-1183. Fulltext not available.

Mahboobi, Siavosh, Dove, Stefan, Bednarski, P. J., Kuhr, S., Burgemeister, Thomas and Schollmeyer, D. (1997) X-Ray Crystal Structure of Woodinine and Conformational Analysis by Means of Semiempirical and 1H-NMR Methods. Journal of Natural Products-Copublished with the Am. Soc. of Pharmacognosy 60 (6), pp. 587-591. Fulltext not available.

Monti, J. M., Jantos, H., Leschke, C., Elz, Sigurd and Schunack, W. (1994) The selective histamine H1-receptor agonist 2-(3-trifluoromethylphenyl)histamine increases waking in the rat. European neuropsychopharmacology 4 (4), pp. 459-462. Fulltext not available.

Lowe, W., Elz, Sigurd, Reiser, H. and Schott, S. (1994) [7-fluoro-4-chromone-3-sulfur compounds]. Archiv der Pharmazie 327 (4), pp. 267-269. Fulltext not available.

Zingel, V., Elz, Sigurd and Schunack, W. (1993) Histamine analogues, XXXV: 2-substituted histamine derivatives containing classical moieties of H2-antagonists--a novel class of H1-agonists. Archiv der Pharmazie 326 (3), pp. 143-151. Fulltext not available.

Radwansky, A., Elz, Sigurd and Lehmann, J. (1993) Lactones, XXY: Synthesis and 5-HT2-receptor affinity of some fluorophenylated alpha-aminomethyllactones. Archiv der Pharmazie 326 (4), pp. 243-244. Fulltext not available.

Elz, Sigurd, Zimmermann, H. and Rehse, K. (1993) Selectivity of sterically fixed tryptamine and 5-methoxytryptamine derivatives for serotonin receptor subtypes, II: Structure-activity relationships and in vitro pharmacology of N-alkyl- and N,N-dialkyl-3- indolylbicyclo-[2.2.1]-heptane-2-amines. Archiv der Pharmazie 326 (11), pp. 893-899. Fulltext not available.

Zingel, V., Elz, Sigurd and Schunack, W. (1992) Histamine analogues. 36th communication. Basically substituted histamine derivatives with H1-agonistic activity. Pharmazie 47 (10), pp. 746-751. Fulltext not available.

Sellier, Christian, Elz, Sigurd, Buschauer, Armin and Schunack, Walter (1992) Histamine analogues: imidazolylalkylguanidines, synthesis and in vitro pharmacology. European Journal of Medicinal Chemistry 27, pp. 27-32. Fulltext not available.

Seifert, Roland, Höer, Ariane, Offermann, Stefan, Buschauer, Armin and Schunack, Walter (1992) Histamine increases Ca^2+ in dibutyryl cyclic AMP-differentiated HL-60 cells via H_1-receptors and is an incomplete secretagogue. Mol. Pharmacol. 42, pp. 227-234.

Hirschfeld, Jürgen, Buschauer, Armin, Elz, Sigurd, Schunack, Walter, Ruat, Martial, Traiffort, Elisabeth and Schwartz, Jean-Charles (1992) Iodoaminopotentidine and related compounds: a new class of ligands with high affinity and selectivity for the histamine H_2-receptor. Journal of Medicinal Chemistry 35, pp. 2231-2238. Fulltext not available.

Sellier, Christian, Elz, Sigurd, Buschauer, Armin and Schunack, Walter (1992) The effect of lipophilic substituents on the H_2-histaminergic activity of some close analogues of impromidine. Arch. Pharm. (Weinheim) 325, pp. 471-476. Fulltext not available.

Sellier, Christian, Elz, Sigurd, Buschauer, Armin and Schunack, Walter (1992) Zur Synthese von (Z)- und (E)-3-(1H-imidazol-4-yl)-2-propenamin und einigen 3-(1H-Imidazol-4-yl)propanaminen. Liebigs Ann. Chem. 1992, pp. 317-322. Fulltext not available.

Elz, Sigurd, Kimmel, Ursula, Buschauer, Armin and Schunack, Walter (1988) Halogenderivate von N-[3-(Imidazol-4-yl)propyl]-N'-(2-phenylthioalkyl)guanidinen. Sci. Pharm. 56, pp. 229-234. Fulltext not available.

Elz, Sigurd and Schunack, Walter (1988) Impromidin-analoge Guanidine: Synthese und Wirkung am Histamin-H2-Rezeptor. 29. Mitteilung: Histamin-Analoga. Arzneimittel-Forschung 38 (3), pp. 327-332. Fulltext not available.

Elz, Sigurd and Schunack, W. (1988) [H2-antagonistic activity of the impromidine analog, cyanoguanidine. 37. H2 antihistaminics]. Arzneimittelforschung 38 (1), pp. 7-10. Fulltext not available.

Elz, Sigurd and Schunack, Walter (1987) Darstellung und H2-agonistische Aktivität alkylsubstituierter 3-(Imidazol-4-yl)propylguanidine. Archiv der Pharmazie 320 (2), pp. 182-185. Fulltext not available.

Buschauer, Armin, Schickaneder, Helmut, Elz, Sigurd, Schunack, Walter, Szelenyi, Istvan, Baumann, Gert and Ahrens, K.-H. (1986) Guanidinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel. Patentanmeldung P 35 12 084.3 (2.4.1985), Offenlegungsschrift DE 35 12 084 A. Fulltext not available.

Schunack, Walter, Buschauer, Armin, Büyüktimkim, Servet, Dziuron, Peter, Elz, Sigurd, Gerhardt, Günter, Lebenstedt, Ernst, Lennartz, Hans-Gerd, Schwarz, Siegfried, Spitzhoff, Margrit and Steffens, Robert (1985) 2. Histamine agonists - chemistry and structure-activity relationships. In: Dahlbom, R. and Nilsson, J. L. G., (eds.) VIIIth International Symposium on Medicinal Chemistry. Swedish Pharmaceutical Press, Stockholm, pp. 169-182. Fulltext not available.

Buschauer, Armin, Schickaneder, Helmut, Schunack, Walter, Elz, Sigurd, Szelenyi, Istvan, Baumann, Gert and Ahrens, K.-H. (1985) Imidazolylalkylguanidine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel. Patentanmeldung 85 114 205.9 (12.11.1985), Eur. Pat. Appl. EP 0 199 845 (5.11.1986). Fulltext not available.

Büyüktimkin, Servet, Elz, Sigurd, Dräger, Martin and Schunack, Walter (1984) Chinazolinone, 1. Mitt. Darstellung, Kristallstruktur und Wirkung von 2-Methyl-3(4-oxo-3-phenyl-thiazolidin-2-ylidenamino)-4-(3H)-chinazolin on. Archiv der Pharmazie 317 (9), pp. 797-802. Fulltext not available.

Elz, Sigurd, Buschauer, Armin, Dräger, M. and Schunack, Walter (1983) Darstellung, Eigenschaften und Kristallstruktur der N-[2-(4,5,6,7-Tetrahydro-2-benzimidazolyl)ethyl]phthalamidsäure. Z. Naturforsch. 38b, pp. 1203-1207. Fulltext not available.

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