Anzahl der Einträge: 93.
2026
Wang, Meng,
Buthut, Maria,
Meinhardt, Jenny,
Otto, Carolin,
Gallaccio, Gerardina,
Fernández-Zapata, Camila,
Teves, Matteo,
Samol, Claudia,
Dettmer, Katja 
,
Heckscher, Simon,
Kamboj, Sakshi,
Bahar, Yozlem,
Conrad, Christian,
Böttcher, Christian,
Kunkel, Desiree,
Ruprecht, Klemens,
Paul, Friedemann,
Oefner, Peter J. 
,
Radbruch, Helena,
Gronwald, Wolfram,
Prüß, Harald und
Böttcher, Chotima
(2026)
Immune-proteo-metabolomic changes link to Aβ and tau pathology in Alzheimer disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association 22 (4), e71359.
Linz, Charlotte,
Tsenova, Kristiyana,
Dettmer, Katja 
,
Ellmann, Lisa,
Oefner, Peter J. 
,
Gronwald, Wolfram,
Farowski, Fedja,
Rüb, Alina M.,
Freedberg, Daniel E.,
Koehler, Philipp,
Borrega, Jorge Garcia,
Naendrup, Jan-Hendrik,
Vehreschild, Maria J. G. T. und
Böll, Boris
(2026)
Integrating intestinal microbiome and urinary metabolome data to predict secondary infection in critically ill patients.
Critical Care.
(Im Druck)
Reindl, Alexander,
Samol, Claudia,
Haerteis, Silke 
,
Zacharias, Helena U.,
Dettmer, Katja 
,
Oefner, Peter J. 
und
Gronwald, Wolfram 
(2026)
Simultaneous determination of free and total metabolite concentrations in proteinaceous specimens by 1D 1H CPMG NMR.
Cell Reports Methods 6 (1), S. 101291.
2025
Babl, Nathalie 
,
Voll, Florian,
Martowicz, Agnieszka,
Bruss, Christina,
Maddaloni, Marianna,
Schmidl, Christian 
,
Rehli, Michael 
,
Loipfinger, Stefan,
Strieder, Nicholas 
,
Gebhard, Claudia 
,
Hoffmann, Petra,
Singh, Sukh M.,
Sala-Hojman, Ada,
Ferretti, Roberta,
Matos, Carina 
,
Simon, Malte 
,
Brummer, Christina,
Schnell, Annette 
,
Hofbauer, Joshua,
Decking, Sonja-Maria,
Hau, Peter 
,
Vollmann-Zwerenz, Arabel,
Dettmer, Katja 
,
Oefner, Peter J. 
,
Althammer, Michael,
Laufs, Johanna,
Friedl, Sarah,
Heinrich, Timo,
Herhaus, Christian,
Evert, Katja 
,
Mayr, Roman 
,
Afonso, Julieta,
Baltazar, Fatima,
Herr, Wolfgang,
Siska, Peter J. 
,
Renner, Kathrin 
und
Kreutz, Marina 
(2025)
Lactic acid promotes an MDSC-like phenotype via HIF1α stabilization with impact on prognosis in renal cell carcinoma.
Cancer Letters 639, S. 218209.
Anders, Wibke,
Yarritu, Alex,
Thiele, Arne,
Szijarto, Istvan Andras,
Rauch, Ariana,
McParland, Victoria,
Kamboj, Sakshi,
Dettmer, Katja 
,
Gronwald, Wolfram,
Oefner, Peter J. 
,
Bartolomaeus, Hendrik und
Wilck, Nicola
(2025)
#3531 The microbiome and its metabolites promote cardiac remodeling in chronic kidney disease via the AhR-IL17A Axis.
Nephrology Dialysis Transplantation 40.
Volltext nicht vorhanden.
Simeth, Jakob 
,
Engelmann, Simon,
Mayr, Roman 
,
Kaelble, Sebastian,
Weber, Florian 
,
Pichler, Renate,
Dettmer, Katja 
,
Oefner, Peter J. 
,
Höring, Marcus 
,
Symeou, Luisa,
Freitag, Katharina,
Wagner, Kilian,
Burger, Maximilian,
Herr, Wolfgang,
Kreutz, Marina 
,
Spang, Rainer 
,
Liebisch, Gerhard 
und
Siska, Peter J. 
(2025)
Lipid metabolism of clear cell renal cell carcinoma predicts survival and affects intratumoral CD8 T cells.
Translational Oncology 61, S. 102513.
Heckscher, Simon,
Ihlo, Nicolas A.,
Schueler, Jan,
Kellermeier, Fabian,
Werner, Jens M. 
,
Nuebel, Barbara,
Gross, Verena,
May, Matthias,
Wullich, Bernd,
Kammerl, Martin,
Gnewuch, Carsten,
Burkhardt, Ralph 
,
Buchholz, Björn,
Pion, Eric,
Aung, Thiha,
Banas, Miriam,
Schlitt, Hans J. 
,
Oefner, Peter J. 
,
Dettmer, Katja 
,
Gronwald, Wolfram 
,
Behr, Merle 
,
Haerteis, Silke 
und
Schmidt, Katharina M.
(2025)
Metabolomic profiling of renal cyst fluid in advanced ADPKD: insights from dialysis and transplantation cohorts.
Metabolomics 21 (4).
Träger, Constantin,
Kaiser, Maria,
Freudenstein, David,
Heckscher, Simon,
Dettmer, Katja 
,
Oefner, Peter J. 
,
Liebisch, Gerhard 
,
Hiergeist, Andreas 
,
Gessner, André 
,
Lee, De-Hyung,
Angstwurm, Klemens 
,
Linker, Ralf A. 
und
Haase, Stefanie 
(2025)
A probiotic approach identifies a Treg-centred immunoregulation via modulation of gut microbiota metabolites in people with multiple sclerosis and healthy individuals.
eBioMedicine 116, S. 105743.
2024
Schwab, Annemarie,
Siddiqui, Mohammad Aarif,
Ramesh, Vignesh,
Gollavilli, Paradesi Naidu,
Turtos, Adriana Martinez,
Møller, Sarah Søgaard,
Pinna, Luisa,
Havelund, Jesper F,
Rømer, Anne Mette A,
Ersan, Pelin Gülizar,
Parma, Beatrice,
Marschall, Sabine,
Dettmer, Katja 
,
Alhusayan, Mohammed,
Bertoglio, Pietro,
Querzoli, Giulia,
Mielenz, Dirk,
Sahin, Ozgur,
Færgeman, Nils J,
Asangani, Irfan A und
Ceppi, Paolo
(2024)
Polyol pathway-generated fructose is indispensable for growth and survival of non-small cell lung cancer.
Cell death & differentiation 32, S. 587-597.
Wrage, Marius,
Holland, Tim,
Nüse, Björn,
Kaltwasser, Johanna,
Fröhlich, Jessica,
Arnold, Harald,
Gießler, Claudia,
Flamann, Cindy,
Bruns, Heiko,
Berges, Johannes,
Daniel, Christoph,
Hoffmann, Markus H.,
Anish, Chakkumkal,
Seeberger, Peter H.,
Bogdan, Christian,
Dettmer, Katja 
,
Rauh, Manfred und
Mattner, Jochen
(2024)
Cell type-specific modulation of metabolic, immune-regulatory, and anti-microbial pathways by CD101.
Mucosal immunology 17 (5), S. 892-910.
2023
Babl, Nathalie,
Decking, Sonja-Maria,
Voll, Florian,
Althammer, Michael,
Sala-Hojman, Ada,
Ferretti, Roberta,
Korf, Clarissa,
Schmidl, Christian,
Schmidleithner, Lisa,
Nerb, Benedikt,
Matos, Carina 
,
Koehl, Gudrun E.,
Siska, Peter J. 
,
Bruss, Christina,
Kellermeier, Fabian,
Dettmer, Katja 
,
Oefner, Peter J. 
,
Wichland, Marvin,
Ugele, Ines,
Bohr, Christopher,
Herr, Wolfgang,
Ramaswamy, Shivapriya,
Heinrich, Timo,
Herhaus, Christian,
Kreutz, Marina 
und
Renner, Kathrin 
(2023)
MCT4 blockade increases the efficacy of immune checkpoint blockade.
Journal for ImmunoTherapy of Cancer 11 (10), e007349.
Buck, Lena,
Schmidt, Tobias,
Feist, Maren,
Schwarzfischer, Philipp,
Kube, Dieter,
Oefner, Peter J. 
,
Zacharias, Helena U.,
Altenbuchinger, Michael 
,
Dettmer, Katja 
,
Gronwald, Wolfram 
und
Spang, Rainer 
(2023)
Anomaly detection in mixed high dimensional molecular data.
Bioinformatics 39 (8), btad501.
Fadil, Fadi 
,
Samol, Claudia,
Berger, Raffaela S. 
,
Kellermeier, Fabian,
Gronwald, Wolfram 
,
Oefner, Peter J. 
und
Dettmer, Katja 
(2023)
Data archive of "Isotope Ratio Outlier Analysis (IROA) for HPLC–TOFMS-Based Metabolomics of Human Urine".
[Datensatz]
Nanadikar, Maithily S.,
Vergel Leon, Ana M.,
Guo, Jia,
van Belle, Gijsbert J.,
Jatho, Aline,
Philip, Elvina S.,
Brandner, Astrid F.,
Böckmann, Rainer A.,
Shi, Runzhu,
Zieseniss, Anke,
Siemssen, Carla M.,
Dettmer, Katja 
,
Brodesser, Susanne,
Schmidtendorf, Marlen,
Lee, Jingyun,
Wu, Hanzhi,
Furdui, Cristina M.,
Brandenburg, Sören,
Burgoyne, Joseph R.,
Bogeski, Ivan,
Riemer, Jan,
Chowdhury, Arpita,
Rehling, Peter,
Bruegmann, Tobias,
Belousov, Vsevolod V. und
Katschinski, Dörthe M.
(2023)
IDH3γ functions as a redox switch regulating mitochondrial energy metabolism and contractility in the heart.
Nature Communications 14 (1).
Volltext nicht vorhanden.
Mauermeir, Michael,
Ölke, Martha,
Hayek, Inaya,
Schulze-Luehrmann, Jan,
Dettmer, Katja 
,
Oefner, Peter J. 
,
Berens, Christian,
Menge, Christian und
Lührmann, Anja
(2023)
Bovine blood derived macrophages are unable to control replication under hypoxic conditions.
Frontiers in immunology 14, S. 960927.
Schoeppe, Robert,
Babl, Nathalie,
Decking, Sonja-Maria,
Schönhammer, Gabriele,
Siegmund, Andreas,
Bruss, Christina,
Dettmer, Katja 
,
Oefner, Peter J. 
,
Frick, Linus,
Weigert, Anna,
Jantsch, Jonathan,
Herr, Wolfgang,
Rehli, Michael 
,
Renner, Kathrin 
und
Kreutz, Marina 
(2023)
Glutamine synthetase expression rescues human dendritic cell survival in a glutamine-deprived environment.
Frontiers in Oncology 13, S. 1-12.
2022
Fadil, Fadi 
,
Samol, Claudia,
Berger, Raffaela S. 
,
Kellermeier, Fabian,
Gronwald, Wolfram 
,
Oefner, Peter J. 
und
Dettmer, Katja 
(2022)
Isotope Ratio Outlier Analysis (IROA) for HPLC–TOFMS-Based Metabolomics of Human Urine.
Metabolites 12 (8), S. 741.
Decking, Sonja-Maria,
Bruss, Christina,
Babl, Nathalie,
Bittner, Sebastian,
Klobuch, Sebastian,
Thomas, Simone 
,
Feuerer, Markus,
Hoffmann, Petra,
Dettmer, Katja 
,
Oefner, Peter J. 
,
Renner, Kathrin 
und
Kreutz, Marina 
(2022)
LDHB Overexpression Can Partially Overcome T Cell Inhibition by Lactic Acid.
International journal of molecular sciences 23 (11), S. 5970.
Frick, Linus,
Hinterland, Linda,
Renner, Kathrin 
,
Vogl, Marion,
Babl, Nathalie,
Heckscher, Simon,
Weigert, Anna,
Weiß, Susanne,
Gläsner, Joachim,
Berger, Raffaela 
,
Oefner, Peter J. 
,
Dettmer, Katja 
,
Kreutz, Marina 
,
Schatz, Valentin und
Jantsch, Jonathan
(2022)
Acidic Microenvironments Found in Cutaneous Leishmania Lesions Curtail NO-Dependent Antiparasitic Macrophage Activity.
Frontiers in Immunology 13, S. 789366.
2021
Tauber, Philipp,
Sinha, Frederick,
Berger, Raffaela S.,
Gronwald, Wolfram,
Dettmer, Katja 
,
Kuhn, Michaela,
Trum, Maximilian,
Maier, Lars S.,
Wagner, Stefan und
Schweda, Frank
(2021)
Empagliflozin Reduces Renal Hyperfiltration in Response to Uninephrectomy, but Is Not Nephroprotective in UNx/DOCA/Salt Mouse Models.
Frontiers in Pharmacology 12, S. 761855.
Siska, Peter J. 
,
Jiao, Jing,
Matos, Carina,
Singer, Katrin,
Berger, Raffaela S. 
,
Dettmer, Katja 
,
Oefner, Peter J. 
,
Cully, Michelle D.,
Wang, Zhonglin,
Quinn III, William J.,
Oliff, Kristen N.,
Wilkins, Benjamin J.,
Christensen, Lanette M.,
Wang, Liqing,
Hancock, Wayne W.,
Baur, Joseph A.,
Levine, Matthew H.,
Ugele, Ines,
Mayr, Roman,
Renner, Kathrin 
,
Zhou, Liang,
Kreutz, Marina 
und
Beier, Ulf H.
(2021)
Kynurenine induces T cell fat catabolism and has limited suppressive effects in vivo.
EBioMedicine 74, S. 103734.
Schöller, Eva,
Marks, James,
Marchand, Virginie 
,
Bruckmann, Astrid,
Powell, Christopher A.,
Reichold, Markus,
Mutti, Christian Daniel 
,
Dettmer, Katja 
,
Feederle, Regina 
,
Hüttelmaier, Stefan,
Helm, Mark,
Oefner, Peter J.,
Minczuk, Michal 
,
Motorin, Yuri 
,
Hafner, Markus und
Meister, Gunter
(2021)
Balancing of mitochondrial translation through METTL8-mediated m3C modification of mitochondrial tRNAs.
Molecular Cell 81 (23), 4810-4825.e12.
Volltext nicht vorhanden.
Arndt, Stephanie,
Fadil, Fadi 
,
Dettmer, Katja 
,
Unger, Petra,
Boskovic, Marko,
Samol, Claudia,
Bosserhoff, Anja-Katrin 
,
Zimmermann, Julia,
Gruber, Michael 
,
Gronwald, Wolfram 
und
Karrer, Sigrid
(2021)
Cold Atmospheric Plasma Changes the Amino Acid Composition in Solutions and Influences the Anti-Tumor Effect on Melanoma Cells.
International Journal of Molecular Sciences 2021 (22), S. 1-22.
Arndt, Stephanie,
Fadil, Fadi 
,
Dettmer, Katja 
,
Unger, Petra,
Boskovic, Marko,
Samol, Claudia,
Bosserhoff, Anja-Katrin 
,
Zimmermann, Julia L.,
Gruber, Michael 
,
Gronwald, Wolfram 
und
Karrer, Sigrid
(2021)
Cold Atmospheric Plasma Changes the Amino Acid Composition of Solutions and Influences the Anti-Tumor Effect on Melanoma Cells.
International Journal of Molecular Sciences 22 (15), S. 7886.
Meedt, Elisabeth,
Hiergeist, Andreas 
,
Gessner, André,
Dettmer, Katja 
,
Liebisch, Gerhard 
,
Ghimire, Sakhila,
Poeck, Hendrik,
Edinger, Matthias,
Wolff, Daniel 
,
Herr, Wolfgang,
Holler, Ernst und
Weber, Daniela
(2021)
Prolonged suppression of butyrate producing bacteria is associated with acute gastrointestinal graft-versus-host disease and transplant related mortality after allogeneic stem cell transplantation.
Clinical Infectious Diseases.
Volltext nicht vorhanden.
Petersen, Anders Ø.,
Jokinen, Martta,
Plichta, Damian R.,
Liebisch, Gerhard 
,
Gronwald, Wolfram,
Dettmer, Katja 
,
Oefner, Peter J.,
Vlamakis, Hera,
Chung, Daniel C.,
Ranki, Annamari und
Xavier, Ramnik J.
(2021)
Cytokine-specific autoantibodies shape the gut microbiome in autoimmune polyendocrine syndrome type 1.
Journal of Allergy and Clinical Immunology, (In Press).
Volltext nicht vorhanden.
Kuo, Selena Z.,
Dettmer, Katja 
,
Annavajhala, Medini K.,
Chong, David H.,
Uhlemann, Anne-Catrin,
Abrams, Julian A.,
Oefner, Peter J. und
Freedberg, Daniel E.
(2021)
Associations between urinary 3-indoxyl sulfate, a gut microbiome-derived biomarker, and patient outcomes after intensive care unit admission.
Journal of Critical Care.
Volltext nicht vorhanden.
Oefner, Peter J. 
,
Dettmer, Katja 
,
Berger, Raffaela Sarah,
Wachsmuth, Christian J.,
Waldhier, Magdalena C.,
Renner-Sattler, Kathrin,
Thomas, Simone,
Chaturvedi, Anuhar 
,
Niller, Hans Helmut,
Bumes, Elisabeth,
Hau, Peter 
,
Proescholdt, Martin A.,
Gronwald, Wolfram 
,
Heuser, Michael und
Kreutz, Marina 
(2021)
Lactonization of the Oncometabolite D-2-Hydroxyglutarate Produces a Novel Endogenous Metabolite.
Cancers 2021 (13), S. 1756.
Dowling, Jennifer K. 
,
Afzal, Remsha 
,
Gearing, Linden J.,
Cervantes-Silva, Mariana P.,
Annett, Stephanie,
Davis, Gavin M.,
De Santi, Chiara,
Assmann, Nadine,
Dettmer, Katja 
,
Gough, Daniel J. 
,
Bantug, Glenn R.,
Hamid, Fidinny I.,
Nally, Frances K.,
Duffy, Conor P.,
Gorman, Aoife L.,
Liddicoat, Alex M.,
Lavelle, Ed C.,
Hess, Christoph,
Oefner, Peter J.,
Finlay, David K.,
Davey, Gavin P.,
Robson, Tracy,
Curtis, Annie M.,
Hertzog, Paul J.,
Williams, Bryan R. G. und
McCoy, Claire E.
(2021)
Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages.
Nature Communications 12, S. 1460.
2019
Renner, Kathrin 
,
Bruss, Christina,
Schnell, Annette,
Koehl, Gudrun,
Becker, Holger M.,
Fante, Matthias,
Menevse, Ayse-Nur,
Kauer, Nathalie,
Blazquez, Raquel,
Hacker, Lisa,
Decking, Sonja-Maria,
Bohn, Toszka,
Faerber, Stephanie,
Evert, Katja,
Aigle, Lisa,
Amslinger, Sabine,
Landa, Maria,
Krijgsman, Oscar,
Rozeman, Elisa A.,
Brummer, Christina,
Siska, Peter J.,
Singer, Katrin,
Pektor, Stefanie,
Miederer, Matthias,
Peter, Katrin,
Gottfried, Eva,
Herr, Wolfgang,
Marchiq, Ibtisam,
Pouyssegur, Jacques,
Roush, William R.,
Ong, SuFey,
Warren, Sarah,
Pukrop, Tobias 
,
Beckhove, Philipp 
,
Lang, Sven A.,
Bopp, Tobias,
Blank, Christian U.,
Cleveland, John L.,
Oefner, Peter J.,
Dettmer, Katja 
,
Selby, Mark und
Kreutz, Marina
(2019)
Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy.
Cell Reports 29 (1), 135-150.e9.
Blazquez, R.,
Rietkoetter, E.,
Wenske, B.,
Wlochowitz, D.,
Sparrer, D.,
Vollmer, E.,
Muller, G.,
Seegerer, J.,
Sun, Xueni,
Dettmer, Katja 
,
Barrantes-Freer, A.,
Stange, L.,
Utpatel, K.,
Bleckmann, A.,
Treiber, H.,
Bohnenberger, H.,
Lenz, C.,
Schulz, M.,
Reimelt, C.,
Hackl, C.,
Grade, M.,
Buyuktas, D.,
Siam, L.,
Balkenhol, M.,
Stadelmann, C.,
Kube, D.,
Krahn, M. P.,
Proescholdt, M. A.,
Riemenschneider, M. J.,
Evert, M.,
Oefner, Peter J. 
,
Klein, C. A.,
Hanisch, U. K.,
Binder, C. und
Pukrop, Tobias 
(2019)
LEF1 supports metastatic brain colonization by regulating glutathione metabolism and increasing ROS resistance in breast cancer.
Int. J. Cancer.
Volltext nicht vorhanden.
Singer, Katrin,
Dettmer, Katja 
,
Unger, Petra,
Schönhammer, Gabriele,
Renner, Kathrin 
,
Peter, Katrin 
,
Siska, Peter J. 
,
Berneburg, Mark 
,
Herr, Wolfgang,
Oefner, Peter J. 
,
Karrer, Sigrid,
Kreutz, Marina 
und
Datz, Elisabeth
(2019)
Topical Diclofenac Reprograms Metabolism and Immune Cell Infiltration in Actinic Keratosis.
Frontiers in Oncology 2019 (9), S. 605.
Singer, Katrin,
Dettmer, Katja 
,
Unger, Petra,
Schoenhammer, Gabriele,
Renner, Kathrin,
Peter, Katrin,
Siska, Peter J.,
Berneburg, Mark 
,
Herr, Wolfgang,
Oefner, Peter J. 
,
Karrer, Sigrid,
Kreutz, Marina 
und
Datz, Elisabeth
(2019)
Topical Diclofenac Reprograms Metabolism and Immune Cell Infiltration in Actinic Keratosis.
Front Oncol 9, S. 605.
Hayek, I.,
Fischer, F.,
Schulze-Luehrmann, J.,
Dettmer, Katja 
,
Sobotta, K.,
Schatz, V.,
Kohl, L.,
Boden, K.,
Lang, R.,
Oefner, Peter J. 
,
Wirtz, S.,
Jantsch, Jonathan und
Luhrmann, A.
(2019)
Limitation of TCA Cycle Intermediates Represents an Oxygen-Independent Nutritional Antibacterial Effector Mechanism of Macrophages.
Cell Rep 26 (13), S. 3502-3510.
2018
Heinrich, Paul,
Kohler, Christian 
,
Ellmann, Lisa,
Kuerner, Paul,
Spang, Rainer,
Oefner, Peter J. 
und
Dettmer, Katja 
(2018)
Correcting for natural isotope abundance and tracer impurity in MS-, MS/MS- and high-resolution-multiple-tracer-data from stable isotope labeling experiments with IsoCorrectoR.
Scientific Reports 8 (17910), S. 1-10.
Reichold, M.,
Klootwijk, E. D.,
Reinders, Jörg 
,
Otto, E. A.,
Milani, M.,
Broeker, C.,
Laing, C.,
Wiesner, J.,
Devi, S.,
Zhou, W.,
Schmitt, R.,
Tegtmeier, I.,
Sterner, C.,
Doellerer, H.,
Renner, K.,
Oefner, Peter J. 
,
Dettmer, Katja 
,
Simbuerger, J.,
Witzgall, R.,
Stanescu, H. C.,
Dumitriu, S.,
Iancu, D.,
Patel, V.,
Mozere, M.,
Tekman, M.,
Jaureguiberry, G.,
Issler, N.,
Kesselheim, A.,
Walsh, S. B.,
Gale, D. P.,
Howie, A. J.,
Martins, J. R.,
Hall, A. M.,
Kasgharian, M.,
O'Brien, K.,
Ferreira, C. R.,
Atwal, P. S.,
Jain, M.,
Hammers, A.,
Charles-Edwards, G.,
Choe, C. U.,
Isbrandt, D.,
Cebrian-Serrano, A.,
Davies, B.,
Sandford, R. N.,
Pugh, C.,
Konecki, D. S.,
Povey, S.,
Bockenhauer, D.,
Lichter-Konecki, U.,
Gahl, W. A.,
Unwin, R. J.,
Warth, Richard 
und
Kleta, R.
(2018)
Glycine Amidinotransferase (GATM), Renal Fanconi Syndrome, and Kidney Failure.
J. Am. Soc. Nephrol. 29 (7), S. 1849-1858.
Volltext nicht vorhanden.
2017
Sekula, P. 
,
Dettmer, Katja 
,
Vogl, Franziska C.,
Gronwald, Wolfram,
Ellmann, Lisa,
Mohney, R. P.,
Eckardt, K. U.,
Suhre, K. 
,
Kastenmüller, Gabi 
,
Oefner, Peter J. und
Köttgen, A.
(2017)
From Discovery to Translation: Characterization of C-Mannosyltryptophan and Pseudouridine as Markers of Kidney Function.
Scientific Reports 7 (1), S. 17400.
Volltext nicht vorhanden.
Assmann, N.,
O'Brien, K. L.,
Donnelly, R. P.,
Dyck, L.,
Zaiatz-Bittencourt, V.,
Loftus, R. M.,
Heinrich, Paul,
Oefner, Peter J.,
Lynch, L.,
Gardiner, C. M.,
Dettmer, Katja 
und
Finlay, D. K. 
(2017)
Srebp-controlled glucose metabolism is essential for NK cell functional responses.
Nat. Immunol. 18 (11), S. 1197-1206.
Volltext nicht vorhanden.
Wallmeier, Jens,
Samol, Claudia,
Ellmann, Lisa,
Zacharias, Helena,
Vogl, Franziska C.,
Garcia, Muriel,
Dettmer, Katja 
,
Oefner, Peter J. und
Gronwald, Wolfram 
(2017)
Quantification of metabolites by NMR spectroscopy in the presence of protein.
Journal of Proteome Research 1535-3893.
Volltext nicht vorhanden.
Maliniemi, P. 
,
Laukkanen, K.,
Vakeva, L.,
Dettmer, Katja 
,
Lipsanen, T.,
Jeskanen, L.,
Bessede, A.,
Oefner, Peter J.,
Kadin, M. E. und
Ranki, A.
(2017)
Biological and clinical significance of tryptophan-catabolizing enzymes in cutaneous T-cell lymphomas.
Oncoimmunology 6 (3), e1273310.
Volltext nicht vorhanden.
Schwarzfischer, Philipp,
Reinders, Jörg,
Dettmer, Katja 
,
Kleo, K.,
Dimitrova, L.,
Hummel, M.,
Feist, M.,
Kube, D.,
Szczepanowski, M.,
Klapper, W.,
Taruttis, Franziska,
Engelmann, Julia C. 
,
Spang, Rainer,
Gronwald, Wolfram und
Oefner, Peter J.
(2017)
Comprehensive metaboproteomics of Burkitt's and diffuse large B-cell lymphoma cell lines and primary tumor tissues reveals distinct differences in pyruvate content and metabolism.
Journal of Proteome Research 16, S. 1105-1120.
Volltext nicht vorhanden.
Weber, Daniela,
Jenq, Robert R.,
Peled, Jonathan U. 
,
Taur, Ying,
Hiergeist, Andreas 
,
Koestler, Josef,
Dettmer, Katja 
,
Weber, Markus,
Wolff, Daniel,
Hahn, Joachim,
Pamer, Eric G.,
Herr, Wolfgang,
Gessner, André,
Oefner, Peter J.,
van den Brink, Marcel R. M. und
Holler, Ernst
(2017)
Microbiota Disruption Induced by Early Use of Broad-Spectrum Antibiotics Is an Independent Risk Factor of Outcome after Allogeneic Stem Cell Transplantation.
Biology of Blood and Marrow Transplantation 23 (5), S. 845-852.
Volltext nicht vorhanden.
2016
Brand, A.,
Singer, K.,
Koehl, G. E.,
Kolitzus, M.,
Schoenhammer, G.,
Thiel, A.,
Matos, C.,
Bruss, C.,
Klobuch, S.,
Peter, K.,
Kastenberger, M.,
Bogdan, C.,
Schleicher, U.,
Mackensen, Andreas,
Ullrich, E. 
,
Fichtner-Feigl, S.,
Kesselring, R.,
Mack, M.,
Ritter, U.,
Schmid, M.,
Blank, C.,
Dettmer, Katja 
,
Oefner, Peter J.,
Hoffmann, P.,
Walenta, S.,
Geissler, E. K.,
Pouyssegur, J.,
Villunger, A.,
Steven, A. 
,
Seliger, B.,
Schreml, S.,
Haferkamp, S.,
Kohl, E.,
Karrer, S.,
Berneburg, Mark,
Herr, Wolfgang,
Mueller-Klieser, W.,
Renner, K. und
Kreutz, Marina
(2016)
LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.
Cell Metabolism (Cell Metab.) 24 (5), S. 657-671.
Volltext nicht vorhanden.
Vogl, Franziska C.,
Mehrl, S.,
Heizinger, L.,
Schlecht, I.,
Zacharias, Helena,
Ellmann, L.,
Nürnberger, N.,
Gronwald, Wolfram,
Leitzmann, M. F.,
Rossert, J.,
Eckardt, K. U.,
Dettmer, Katja 
und
Oefner, Peter J.
(2016)
Evaluation of dilution and normalization strategies to correct for urinary output in HPLC-HRTOFMS metabolomics.
Analytical and Bioanalytical Chemistry (Anal Bioanal Chem).
Volltext nicht vorhanden.
Altenbuchinger, Michael,
Rehberg, Thorsten,
Zacharias, Helena,
Stämmler, Frank,
Dettmer, Katja 
,
Weber, Daniela,
Hiergeist, Andreas,
Gessner, Andre,
Holler, Ernst,
Oefner, Peter J. und
Spang, Rainer
(2016)
Reference point insensitive molecular data analysis.
Bioinformatics.
Seliger, Corinna,
Meyer, A. L.,
Renner, K.,
Leidgens, V.,
Moeckel, S.,
Jachnik, B.,
Dettmer, Katja 
,
Tischler, U.,
Gerthofer, V.,
Rauer, L.,
Uhl, M.,
Proescholdt, M.,
Bogdahn, U.,
Riemenschneider, M. J.,
Oefner, Peter J.,
Kreutz, M.,
Vollmann-Zwerenz, A. und
Hau, Peter
(2016)
Metformin inhibits proliferation and migration of glioblastoma cells independently of TGF-β2.
Cell Cycle 15 (13), S. 1755-1766.
Volltext nicht vorhanden.
Assmann, Nadine,
Dettmer, Katja 
,
Simbürger, Johann,
Broeker, Carsten,
Nuernberger, Nadine,
Renner, Kathrin,
Courtneidge, H.,
Klootwijk, E. D.,
Duerkop, Axel 
,
Hall, A.,
Kleta, R.,
Oefner, Peter J. 
,
Reichold, Markus und
Reinders, Jörg
(2016)
Renal Fanconi Syndrome Is Caused by a Mistargeting-Based Mitochondriopathy.
Cell Reports (Cell Rep) 15 (7), S. 1423-1429.
Weber, Daniela,
Oefner, Peter J.,
Dettmer, Katja 
,
Hiergeist, Andreas,
Koestler, Josef,
Gessner, Andre,
Weber, Markus,
Stämmler, Frank,
Hahn, Joachim,
Wolff, Daniel,
Herr, Wolfgang und
Holler, Ernst
(2016)
Rifaximin preserves intestinal microbiota balance in patients undergoing allogeneic stem cell transplantation.
Bone Marrow Transplant..
Volltext nicht vorhanden.
Voelxen, N. F.,
Walenta, S.,
Proescholdt, Martin A.,
Dettmer, Katja 
,
Pusch, S. 
und
Mueller-Klieser, W.
(2016)
Quantitative Imaging of D-2-Hydroxyglutarate in Selected Histological Tissue Areas by a Novel Bioluminescence Technique.
Frontiers in Oncology 6, S. 46.
Henrich, F.,
Singer, Katrin,
Poller, K.,
Bernhardt, L.,
Strobl, C. 
,
Ritter, Axel P.,
Gottfried, E.,
Peter, Katrin,
Dettmer, Katja 
,
Oefner, Peter J.,
Bosserhoff, Anja-Katrin und
Kreutz, Marina
(2016)
Suppressive effects of tumor cell-derived 5′-deoxy-5′-methylthioadenosine on human T cells.
OncoImmunology 5, e1184802.
Volltext nicht vorhanden.
2015
Sekula, Peggy 
,
Goek, Oemer-Necmi,
Quaye, Lydia,
Barrios, Clara,
Levey, Andrew S.,
Römisch-Margl, Werner,
Menni, Cristina 
,
Yet, Idil,
Gieger, Christian,
Inker, Lesley A.,
Adamski, Jerzy,
Gronwald, Wolfram,
Illig, Thomas,
Dettmer, Katja 
,
Krumsiek, Jan,
Oefner, Peter J. 
,
Valdes, Ana M. 
,
Meisinger, Christa,
Coresh, Josef,
Spector, Tim D.,
Mohney, Robert P.,
Suhre, Karsten,
Kastenmüller, Gabi und
Köttgen, Anna
(2015)
A Metabolome-Wide Association Study of Kidney Function and Disease in the General Population.
Journal of the American Society of Nephrology (JASN) 27 (4), S. 1175-1188.
Leisz, Sandra,
Schulz, Kristin,
Erb, Susanne,
Oefner, Peter J. 
,
Dettmer, Katja 
,
Mougiakakos, Dimitrios,
Wang, Ena,
Marincola, Francesco M.,
Stehle, Franziska und
Seliger, Barbara
(2015)
Distinct von Hippel-Lindau gene and hypoxia-regulated alterations in gene and protein expression patterns of renal cell carcinoma and their effects on metabolism.
Oncotarget 6 (13), S. 11395-11406.
Jantsch, Jonathan,
Schatz, Valentin,
Dettmer, Katja 
,
Dick, Christopher,
Ehrenschwender, Martin 
,
Hellerbrand, Claus und
Oefner, Peter J. 
(2015)
Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen.
Cell Reports 2015 (13), S. 2048-2055.
Weber, Daniela,
Oefner, Peter J. 
,
Hiergeist, Andreas,
Koestler, Josef,
Gessner, Andre,
Weber, Markus,
Hahn, Joachim,
Wolff, Daniel,
Stämmler, Frank,
Spang, Rainer,
Herr, Wolfgang,
Dettmer, Katja 
und
Holler, Ernst
(2015)
Low urinary indoxyl sulfate levels early after transplantation reflect a disrupted microbiome and are associated with poor outcome.
Blood 126 (14), S. 1723-1728.
2014
2013
Thomas, Anja,
Klein, Matthias S. 
,
Stevens, Axel Peter,
Reinders, Yvonne,
Hellerbrand, Claus,
Dettmer, Katja 
,
Gronwald, Wolfram,
Oefner, Peter J. 
und
Reinders, Jörg
(2013)
Changes in the hepatic mitochondrial and membrane proteome in mice fed a non-alcoholic steatohepatitis inducing diet.
Journal of proteomics 80, S. 107-122.
Volltext nicht vorhanden.
Klein, Matthias S. 
,
Almstetter, Martin F.,
Nürnberger, Nadine,
Sigl, Gregor,
Gronwald, Wolfram,
Wiedemann, Steffi,
Dettmer, Katja 
und
Oefner, Peter J. 
(2013)
Correlations between milk and plasma levels of amino and carboxylic acids in dairy cows.
Journal of Proteome Research 12 (11), S. 5223-5232.
Dettmer, Katja 
,
Vogl, Franziska C.,
Ritter, Axel P.,
Zhu, Wentao,
Nürnberger, Nadine,
Kreutz, Marina,
Oefner, Peter J. 
,
Gronwald, Wolfram und
Gottfried, Eva
(2013)
Distinct metabolic differences between various human cancer and primary cells.
ELECTROPHORESIS 34 (19), S. 2836-2847.
Volltext nicht vorhanden.
Czech, Barbara,
Dettmer, Katja 
,
Valletta, Daniela,
Saugspier, Michael Sebastian,
Koch, Andreas,
Stevens, Axel Peter,
Thasler, Wolfgang E.,
Müller, Martina,
Oefner, Peter J. 
,
Bosserhoff, Anja-Katrin 
und
Hellerbrand, Claus
(2013)
Expression and function of methylthioadenosine phosphorylase in chronic liver disease.
PloS ONE 8 (12), e80703.
Riechers, A.,
Schmidt, J.,
Dettmer, Katja 
,
Oefner, Peter J. 
,
Jachimczak, P.,
Schneider, A. und
Bosserhoff, Anja-Katrin 
(2013)
Inducing anti-tumor cytokines and an immune response in melanoma by inhibition of MIA using the peptide AR71.
Eur J Dermatol 23 (6), S. 820-825.
Volltext nicht vorhanden.
Kreutz, Marina,
Gottfried, Eva,
Lang, Sven A.,
Renner, Kathrin,
Bosserhoff, Anja-Katrin 
,
Gronwald, Wolfram,
Rehli, Michael 
,
Einhell, Sabine,
Gedig, Isabel,
Singer, Katrin,
Seilbeck, Anton,
Mackensen, Andreas,
Grauer, Oliver,
Hau, Peter,
Dettmer, Katja 
,
Andreesen, Reinhard und
Oefner, Peter 
(2013)
New aspects of an old drug: Diclofenac targets MYC and glucose metabolism in tumor cells.
PLoS ONE 8 (7), e66987.
2012
Czech, B.,
Saugspier, M.,
Dettmer, K. 
,
Stevens, A.,
Dorn, C.,
Valletta, D.,
Bosserhoff, A.,
Oefner, P.J. 
und
Hellerbrand, C.
(2012)
364 DOWNREGULATION OF METHYLTHIOADENOSINE PHOSPHORYLASE (MTAP) EXPRESSION IN CHRONIC LIVER DISEASE PROMOTES HEPATIC INFLAMMATION AND FIBROSIS.
Journal of Hepatology 56, S147-S148.
Volltext nicht vorhanden.
van der Goot, Annemieke,
Zhu, Wentao,
Vázquez-Manrique, Rafael 
,
Seinstra, Renée I.,
Dettmer, Katja 
,
Michels, Helen,
Farina, Francesca,
Krijnen, Jasper,
Melki, Ronald,
Buijsman, Rogier C.,
Ruiz Silva, Mariana,
Thijssen, Karen L.,
Kema, Ido P.,
Neri, Christian 
,
Oefner, Peter J. 
und
Nollen, Ellen A. A.
(2012)
Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation.
Proceedings of the National Academy of Sciences of the United States of America 109 (37), S. 14912-7.
Volltext nicht vorhanden.
Thomas, Anja,
Stevens, Axel Peter,
Klein, Matthias S. 
,
Hellerbrand, Claus,
Dettmer, Katja 
,
Gronwald, Wolfram,
Oefner, Peter J. 
und
Reinders, Jörg
(2012)
Early changes in the liver-soluble proteome from mice fed a nonalcoholic steatohepatitis inducing diet.
Proteomics 12 (9), S. 1437-1451.
Volltext nicht vorhanden.
2011
Kirovski, Georgi,
Stevens, Axel Peter,
Czech, Barbara,
Dettmer, Katja 
,
Weiss, Thomas S. 
,
Wild, Peter,
Hartmann, Arndt,
Bosserhoff, Anja-Katrin 
,
Oefner, Peter J. 
und
Hellerbrand, Claus
(2011)
Down-regulation of methylthioadenosine phosphorylase (MTAP) induces progression of hepatocellular carcinoma via accumulation of 5'-deoxy-5'-methylthioadenosine (MTA).
The American journal of pathology 178 (3), S. 1145-1152.
Volltext nicht vorhanden.
Waldhier, Magdalena Ch.,
Almstetter, Martin F.,
Nürnberger, Nadine,
Gruber, Michael 
,
Dettmer, Katja 
und
Oefner, Peter J. 
(2011)
Improved enantiomer resolution and quantification of free D-amino acids in serum and urine by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry.
Journal of chromatography A 1218 (28), S. 4537-4544.
Volltext nicht vorhanden.
Dettmer, Katja 
,
Nürnberger, Nadine,
Kaspar, Hannelore,
Gruber, Michael 
,
Almstetter, Martin F. und
Oefner, Peter J. 
(2011)
Metabolite extraction from adherently growing mammalian cells for metabolomics studies: optimization of harvesting and extraction protocols.
Analytical and bioanalytical chemistry 399 (3), S. 1127-1139.
Volltext nicht vorhanden.
Wachsmuth, Christian,
Almstetter, Martin F.,
Waldhier, Magdalena Ch.,
Gruber, Michael 
,
Nürnberger, Nadine,
Oefner, Peter J. 
und
Dettmer, Katja 
(2011)
Performance evaluation of gas chromatography-atmospheric pressure chemical ionization-time-of-flight mass spectrometry for metabolic fingerprinting and profiling.
Analytical chemistry 83 (19), S. 7514-7322.
Volltext nicht vorhanden.
Zhu, Wentao,
Stevens, Axel Peter,
Dettmer, Katja 
,
Gottfried, Eva,
Hoves, Sabine 
,
Kreutz, Marina,
Holler, Ernst,
Canelas, André B.,
Kema, Ido und
Oefner, Peter J. 
(2011)
Quantitative profiling of tryptophan metabolites in serum, urine, and cell culture supernatants by liquid chromatography-tandem mass spectrometry.
Analytical and bioanalytical chemistry 401 (10), S. 3249-3261.
Volltext nicht vorhanden.
2010
Dettmer, Katja 
,
Almstetter, Martin F.,
Appel, Inka,
Nürnberger, Nadine,
Schlamberger, Gregor,
Gronwald, Wolfram,
Meyer, Heinrich H. D. und
Oefner, Peter J. 
(2010)
Comparison of serum versus plasma collection in gas chromatography--mass spectrometry-based metabolomics.
Electrophoresis 31 (14), S. 2365-2373.
Volltext nicht vorhanden.
Dietl, Katrin,
Renner, Kathrin,
Dettmer, Katja 
,
Timischl, Birgit,
Eberhart, Karin,
Dorn, Christoph,
Hellerbrand, Claus,
Kastenberger, Michael,
Kunz-Schughart, Leoni A.,
Oefner, Peter J. 
,
Andreesen, Reinhard,
Gottfried, Eva und
Kreutz, Marina
(2010)
Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes.
Journal of immunology 184 (3), S. 1200-1209.
Volltext nicht vorhanden.
Klein, Matthias S. 
,
Almstetter, Martin F.,
Schlamberger, G.,
Nürnberger, Nadine,
Dettmer, Katja 
,
Oefner, Peter J. 
,
Meyer, H. H. D.,
Wiedemann, Steffi und
Gronwald, Wolfram
(2010)
Nuclear magnetic resonance and mass spectrometry-based milk metabolomics in dairy cows during early and late lactation.
Journal of dairy science 93 (4), S. 1539-1550.
Volltext nicht vorhanden.
Amann, Thomas,
Bataille, Frauke,
Spruss, Thilo,
Dettmer, Katja 
,
Wild, Peter J.,
Liedtke, Christian 
,
Mühlbauer, Marcus,
Kiefer, Paul,
Oefner, Peter J. 
,
Trautwein, Christian,
Bosserhoff, Anja-Katrin 
und
Hellerbrand, Claus
(2010)
Reduced expression of fibroblast growth factor receptor 2IIIb in hepatocellular carcinoma induces a more aggressive growth.
The American journal of pathology 176 (3), S. 1433-1442.
Volltext nicht vorhanden.
2009
Stevens, Axel Peter,
Spangler, Barbara,
Wallner, Susanne,
Kreutz, Marina,
Dettmer, Katja 
,
Oefner, Peter J. 
und
Bosserhoff, Anja-Katrin 
(2009)
Direct and tumor microenvironment mediated influences of 5'-deoxy-5'-(methylthio)adenosine on tumor progression of malignant melanoma.
Journal of cellular biochemistry 106 (2), S. 210-219.
Volltext nicht vorhanden.
Almstetter, Martin F.,
Appel, Inka,
Gruber, Michael 
,
Lottaz, Claudio,
Timischl, Birgit,
Spang, Rainer,
Dettmer, Katja 
und
Oefner, Peter J.
(2009)
Integrative normalization and comparative analysis for metabolic fingerprinting by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry.
Analytical chemistry 81 (14), S. 5731-5739.
Volltext nicht vorhanden.
Baumann, Fusun,
Leukel, Petra,
Doerfelt, Anett,
Beier, Christoph P.,
Dettmer, Katja 
,
Oefner, Peter J. 
,
Kastenberger, Michael,
Kreutz, Marina,
Nickl-Jockschat, Thomas 
,
Bogdahn, Ulrich,
Bosserhoff, Anja-Katrin 
und
Hau, Peter
(2009)
Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2.
Neuro-oncology 11 (4), S. 368-380.
Volltext nicht vorhanden.
Kaspar, Hannelore,
Dettmer, Katja 
,
Chan, Queenie 
,
Daniels, Scott,
Nimkar, Subodh,
Daviglus, Martha L.,
Stamler, Jeremiah,
Elliott, Paul 
und
Oefner, Peter J. 
(2009)
Urinary amino acid analysis: a comparison of iTRAQ-LC-MS/MS, GC-MS, and amino acid analyzer.
Journal of chromatography B 877 (20-21), S. 1838-1846.
Volltext nicht vorhanden.
2008
Timischl, B.,
Dettmer, Katja 
,
Kaspar, H.,
Thieme, M. und
Oefner, Peter J. 
(2008)
Development of a quantitative, validated capillary electrophoresis-time of flight-mass spectrometry method with integrated high-confidence analyte identification for metabolomics.
Electrophoresis 29 (10), S. 2203-2214.
Volltext nicht vorhanden.
Gronwald, Wolfram,
Klein, M. S.,
Kaspar, Hannelore,
Fagerer, S. R.,
Nürnberger, N.,
Dettmer, Katja 
,
Bertsch, T. und
Oefner, Peter J. 
(2008)
Urinary metabolite quantification employing 2D NMR spectroscopy.
Anal. Chem. 80 (23), S. 9288-9297.
Volltext nicht vorhanden.
2007
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