Startseite UR
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Linz, Charlotte, Tsenova, Kristiyana, Dettmer, Katja
, Ellmann, Lisa, Oefner, Peter J.
, Gronwald, Wolfram, Farowski, Fedja, Rüb, Alina M., Freedberg, Daniel E., Koehler, Philipp, Borrega, Jorge Garcia, Naendrup, Jan-Hendrik, Vehreschild, Maria J. G. T. und Böll, Boris
(2026)
Integrating intestinal microbiome and urinary metabolome data to predict secondary infection in critically ill patients.
Critical Care.
(Im Druck)
Reindl, Alexander, Samol, Claudia, Haerteis, Silke
, Zacharias, Helena U., Dettmer, Katja
, Oefner, Peter J.
und Gronwald, Wolfram
(2026)
Simultaneous determination of free and total metabolite concentrations in proteinaceous specimens by 1D 1H CPMG NMR.
Cell Reports Methods 6 (1), S. 101291.
Babl, Nathalie
, Voll, Florian, Martowicz, Agnieszka, Bruss, Christina, Maddaloni, Marianna, Schmidl, Christian
, Rehli, Michael
, Loipfinger, Stefan, Strieder, Nicholas
, Gebhard, Claudia
, Hoffmann, Petra, Singh, Sukh M., Sala-Hojman, Ada, Ferretti, Roberta, Matos, Carina
, Simon, Malte
, Brummer, Christina, Schnell, Annette
, Hofbauer, Joshua, Decking, Sonja-Maria, Hau, Peter
, Vollmann-Zwerenz, Arabel, Dettmer, Katja
, Oefner, Peter J.
, Althammer, Michael, Laufs, Johanna, Friedl, Sarah, Heinrich, Timo, Herhaus, Christian, Evert, Katja
, Mayr, Roman
, Afonso, Julieta, Baltazar, Fatima, Herr, Wolfgang, Siska, Peter J.
, Renner, Kathrin
und Kreutz, Marina
(2025)
Lactic acid promotes an MDSC-like phenotype via HIF1α stabilization with impact on prognosis in renal cell carcinoma.
Cancer Letters 639, S. 218209.
, Gronwald, Wolfram, Oefner, Peter J.
, Bartolomaeus, Hendrik und Wilck, Nicola
(2025)
#3531 The microbiome and its metabolites promote cardiac remodeling in chronic kidney disease via the AhR-IL17A Axis.
Nephrology Dialysis Transplantation 40.
Volltext nicht vorhanden.
Simeth, Jakob
, Engelmann, Simon, Mayr, Roman
, Kaelble, Sebastian, Weber, Florian
, Pichler, Renate, Dettmer, Katja
, Oefner, Peter J.
, Höring, Marcus
, Symeou, Luisa, Freitag, Katharina, Wagner, Kilian, Burger, Maximilian, Herr, Wolfgang, Kreutz, Marina
, Spang, Rainer
, Liebisch, Gerhard
und Siska, Peter J.
(2025)
Lipid metabolism of clear cell renal cell carcinoma predicts survival and affects intratumoral CD8 T cells.
Translational Oncology 61, S. 102513.
Heckscher, Simon, Ihlo, Nicolas A., Schueler, Jan, Kellermeier, Fabian, Werner, Jens M.
, Nuebel, Barbara, Gross, Verena, May, Matthias, Wullich, Bernd, Kammerl, Martin, Gnewuch, Carsten, Burkhardt, Ralph
, Buchholz, Björn, Pion, Eric, Aung, Thiha, Banas, Miriam, Schlitt, Hans J.
, Oefner, Peter J.
, Dettmer, Katja
, Gronwald, Wolfram
, Behr, Merle
, Haerteis, Silke
und Schmidt, Katharina M.
(2025)
Metabolomic profiling of renal cyst fluid in advanced ADPKD: insights from dialysis and transplantation cohorts.
Metabolomics 21 (4).
Träger, Constantin, Kaiser, Maria, Freudenstein, David, Heckscher, Simon, Dettmer, Katja
, Oefner, Peter J.
, Liebisch, Gerhard
, Hiergeist, Andreas
, Gessner, André
, Lee, De-Hyung, Angstwurm, Klemens
, Linker, Ralf A.
und Haase, Stefanie
(2025)
A probiotic approach identifies a Treg-centred immunoregulation via modulation of gut microbiota metabolites in people with multiple sclerosis and healthy individuals.
eBioMedicine 116, S. 105743.
Schwab, Annemarie, Siddiqui, Mohammad Aarif, Ramesh, Vignesh, Gollavilli, Paradesi Naidu, Turtos, Adriana Martinez, Møller, Sarah Søgaard, Pinna, Luisa, Havelund, Jesper F, Rømer, Anne Mette A, Ersan, Pelin Gülizar, Parma, Beatrice, Marschall, Sabine, Dettmer, Katja
, Alhusayan, Mohammed, Bertoglio, Pietro, Querzoli, Giulia, Mielenz, Dirk, Sahin, Ozgur, Færgeman, Nils J, Asangani, Irfan A und Ceppi, Paolo
(2024)
Polyol pathway-generated fructose is indispensable for growth and survival of non-small cell lung cancer.
Cell death & differentiation 32, S. 587-597.
Wrage, Marius, Holland, Tim, Nüse, Björn, Kaltwasser, Johanna, Fröhlich, Jessica, Arnold, Harald, Gießler, Claudia, Flamann, Cindy, Bruns, Heiko, Berges, Johannes, Daniel, Christoph, Hoffmann, Markus H., Anish, Chakkumkal, Seeberger, Peter H., Bogdan, Christian, Dettmer, Katja
, Rauh, Manfred und Mattner, Jochen
(2024)
Cell type-specific modulation of metabolic, immune-regulatory, and anti-microbial pathways by CD101.
Mucosal immunology 17 (5), S. 892-910.
Babl, Nathalie, Decking, Sonja-Maria, Voll, Florian, Althammer, Michael, Sala-Hojman, Ada, Ferretti, Roberta, Korf, Clarissa, Schmidl, Christian, Schmidleithner, Lisa, Nerb, Benedikt, Matos, Carina
, Koehl, Gudrun E., Siska, Peter J.
, Bruss, Christina, Kellermeier, Fabian, Dettmer, Katja
, Oefner, Peter J.
, Wichland, Marvin, Ugele, Ines, Bohr, Christopher, Herr, Wolfgang, Ramaswamy, Shivapriya, Heinrich, Timo, Herhaus, Christian, Kreutz, Marina
und Renner, Kathrin
(2023)
MCT4 blockade increases the efficacy of immune checkpoint blockade.
Journal for ImmunoTherapy of Cancer 11 (10), e007349.
Buck, Lena, Schmidt, Tobias, Feist, Maren, Schwarzfischer, Philipp, Kube, Dieter, Oefner, Peter J.
, Zacharias, Helena U., Altenbuchinger, Michael
, Dettmer, Katja
, Gronwald, Wolfram
und Spang, Rainer
(2023)
Anomaly detection in mixed high dimensional molecular data.
Bioinformatics 39 (8), btad501.
, Brodesser, Susanne, Schmidtendorf, Marlen, Lee, Jingyun, Wu, Hanzhi, Furdui, Cristina M., Brandenburg, Sören, Burgoyne, Joseph R., Bogeski, Ivan, Riemer, Jan, Chowdhury, Arpita, Rehling, Peter, Bruegmann, Tobias, Belousov, Vsevolod V. und Katschinski, Dörthe M.
(2023)
IDH3γ functions as a redox switch regulating mitochondrial energy metabolism and contractility in the heart.
Nature Communications 14 (1).
Volltext nicht vorhanden.
Mauermeir, Michael, Ölke, Martha, Hayek, Inaya, Schulze-Luehrmann, Jan, Dettmer, Katja
, Oefner, Peter J.
, Berens, Christian, Menge, Christian und Lührmann, Anja
(2023)
Bovine blood derived macrophages are unable to control replication under hypoxic conditions.
Frontiers in immunology 14, S. 960927.
Schoeppe, Robert, Babl, Nathalie, Decking, Sonja-Maria, Schönhammer, Gabriele, Siegmund, Andreas, Bruss, Christina, Dettmer, Katja
, Oefner, Peter J.
, Frick, Linus, Weigert, Anna, Jantsch, Jonathan, Herr, Wolfgang, Rehli, Michael
, Renner, Kathrin
und Kreutz, Marina
(2023)
Glutamine synthetase expression rescues human dendritic cell survival in a glutamine-deprived environment.
Frontiers in Oncology 13, S. 1-12.
Fadil, Fadi
, Samol, Claudia, Berger, Raffaela S.
, Kellermeier, Fabian, Gronwald, Wolfram
, Oefner, Peter J.
und Dettmer, Katja
(2022)
Isotope Ratio Outlier Analysis (IROA) for HPLC–TOFMS-Based Metabolomics of Human Urine.
Metabolites 12 (8), S. 741.
Decking, Sonja-Maria, Bruss, Christina, Babl, Nathalie, Bittner, Sebastian, Klobuch, Sebastian, Thomas, Simone
, Feuerer, Markus, Hoffmann, Petra, Dettmer, Katja
, Oefner, Peter J.
, Renner, Kathrin
und Kreutz, Marina
(2022)
LDHB Overexpression Can Partially Overcome T Cell Inhibition by Lactic Acid.
International journal of molecular sciences 23 (11), S. 5970.
Frick, Linus, Hinterland, Linda, Renner, Kathrin
, Vogl, Marion, Babl, Nathalie, Heckscher, Simon, Weigert, Anna, Weiß, Susanne, Gläsner, Joachim, Berger, Raffaela
, Oefner, Peter J.
, Dettmer, Katja
, Kreutz, Marina
, Schatz, Valentin und Jantsch, Jonathan
(2022)
Acidic Microenvironments Found in Cutaneous Leishmania Lesions Curtail NO-Dependent Antiparasitic Macrophage Activity.
Frontiers in Immunology 13, S. 789366.
Tauber, Philipp, Sinha, Frederick, Berger, Raffaela S., Gronwald, Wolfram, Dettmer, Katja
, Kuhn, Michaela, Trum, Maximilian, Maier, Lars S., Wagner, Stefan und Schweda, Frank
(2021)
Empagliflozin Reduces Renal Hyperfiltration in Response to Uninephrectomy, but Is Not Nephroprotective in UNx/DOCA/Salt Mouse Models.
Frontiers in Pharmacology 12, S. 761855.
Siska, Peter J.
, Jiao, Jing, Matos, Carina, Singer, Katrin, Berger, Raffaela S.
, Dettmer, Katja
, Oefner, Peter J.
, Cully, Michelle D., Wang, Zhonglin, Quinn III, William J., Oliff, Kristen N., Wilkins, Benjamin J., Christensen, Lanette M., Wang, Liqing, Hancock, Wayne W., Baur, Joseph A., Levine, Matthew H., Ugele, Ines, Mayr, Roman, Renner, Kathrin
, Zhou, Liang, Kreutz, Marina
und Beier, Ulf H.
(2021)
Kynurenine induces T cell fat catabolism and has limited suppressive effects in vivo.
EBioMedicine 74, S. 103734.
, Bruckmann, Astrid, Powell, Christopher A., Reichold, Markus, Mutti, Christian Daniel
, Dettmer, Katja
, Feederle, Regina
, Hüttelmaier, Stefan, Helm, Mark, Oefner, Peter J., Minczuk, Michal
, Motorin, Yuri
, Hafner, Markus und Meister, Gunter
(2021)
Balancing of mitochondrial translation through METTL8-mediated m3C modification of mitochondrial tRNAs.
Molecular Cell 81 (23), 4810-4825.e12.
Volltext nicht vorhanden.
Arndt, Stephanie, Fadil, Fadi
, Dettmer, Katja
, Unger, Petra, Boskovic, Marko, Samol, Claudia, Bosserhoff, Anja-Katrin
, Zimmermann, Julia, Gruber, Michael
, Gronwald, Wolfram
und Karrer, Sigrid
(2021)
Cold Atmospheric Plasma Changes the Amino Acid Composition in Solutions and Influences the Anti-Tumor Effect on Melanoma Cells.
International Journal of Molecular Sciences 2021 (22), S. 1-22.
Arndt, Stephanie, Fadil, Fadi
, Dettmer, Katja
, Unger, Petra, Boskovic, Marko, Samol, Claudia, Bosserhoff, Anja-Katrin
, Zimmermann, Julia L., Gruber, Michael
, Gronwald, Wolfram
und Karrer, Sigrid
(2021)
Cold Atmospheric Plasma Changes the Amino Acid Composition of Solutions and Influences the Anti-Tumor Effect on Melanoma Cells.
International Journal of Molecular Sciences 22 (15), S. 7886.
, Gessner, André, Dettmer, Katja
, Liebisch, Gerhard
, Ghimire, Sakhila, Poeck, Hendrik, Edinger, Matthias, Wolff, Daniel
, Herr, Wolfgang, Holler, Ernst und Weber, Daniela
(2021)
Prolonged suppression of butyrate producing bacteria is associated with acute gastrointestinal graft-versus-host disease and transplant related mortality after allogeneic stem cell transplantation.
Clinical Infectious Diseases.
Volltext nicht vorhanden.
, Gronwald, Wolfram, Dettmer, Katja
, Oefner, Peter J., Vlamakis, Hera, Chung, Daniel C., Ranki, Annamari und Xavier, Ramnik J.
(2021)
Cytokine-specific autoantibodies shape the gut microbiome in autoimmune polyendocrine syndrome type 1.
Journal of Allergy and Clinical Immunology, (In Press).
Volltext nicht vorhanden.
, Annavajhala, Medini K., Chong, David H., Uhlemann, Anne-Catrin, Abrams, Julian A., Oefner, Peter J. und Freedberg, Daniel E.
(2021)
Associations between urinary 3-indoxyl sulfate, a gut microbiome-derived biomarker, and patient outcomes after intensive care unit admission.
Journal of Critical Care.
Volltext nicht vorhanden.
Oefner, Peter J.
, Dettmer, Katja
, Berger, Raffaela Sarah, Wachsmuth, Christian J., Waldhier, Magdalena C., Renner-Sattler, Kathrin, Thomas, Simone, Chaturvedi, Anuhar
, Niller, Hans Helmut, Bumes, Elisabeth, Hau, Peter
, Proescholdt, Martin A., Gronwald, Wolfram
, Heuser, Michael und Kreutz, Marina
(2021)
Lactonization of the Oncometabolite D-2-Hydroxyglutarate Produces a Novel Endogenous Metabolite.
Cancers 2021 (13), S. 1756.
Dowling, Jennifer K.
, Afzal, Remsha
, Gearing, Linden J., Cervantes-Silva, Mariana P., Annett, Stephanie, Davis, Gavin M., De Santi, Chiara, Assmann, Nadine, Dettmer, Katja
, Gough, Daniel J.
, Bantug, Glenn R., Hamid, Fidinny I., Nally, Frances K., Duffy, Conor P., Gorman, Aoife L., Liddicoat, Alex M., Lavelle, Ed C., Hess, Christoph, Oefner, Peter J., Finlay, David K., Davey, Gavin P., Robson, Tracy, Curtis, Annie M., Hertzog, Paul J., Williams, Bryan R. G. und McCoy, Claire E.
(2021)
Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages.
Nature Communications 12, S. 1460.
und Dettmer, Katja
(2019)
Quantification and 13C-Tracer analysis of total reduced glutathione by HPLC-QTOFMS/MS.
Anal. Chim. Acta 1080, S. 127-137.
Volltext nicht vorhanden.
Renner, Kathrin
, Bruss, Christina, Schnell, Annette, Koehl, Gudrun, Becker, Holger M., Fante, Matthias, Menevse, Ayse-Nur, Kauer, Nathalie, Blazquez, Raquel, Hacker, Lisa, Decking, Sonja-Maria, Bohn, Toszka, Faerber, Stephanie, Evert, Katja, Aigle, Lisa, Amslinger, Sabine, Landa, Maria, Krijgsman, Oscar, Rozeman, Elisa A., Brummer, Christina, Siska, Peter J., Singer, Katrin, Pektor, Stefanie, Miederer, Matthias, Peter, Katrin, Gottfried, Eva, Herr, Wolfgang, Marchiq, Ibtisam, Pouyssegur, Jacques, Roush, William R., Ong, SuFey, Warren, Sarah, Pukrop, Tobias
, Beckhove, Philipp
, Lang, Sven A., Bopp, Tobias, Blank, Christian U., Cleveland, John L., Oefner, Peter J., Dettmer, Katja
, Selby, Mark und Kreutz, Marina
(2019)
Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy.
Cell Reports 29 (1), 135-150.e9.
, Barrantes-Freer, A., Stange, L., Utpatel, K., Bleckmann, A., Treiber, H., Bohnenberger, H., Lenz, C., Schulz, M., Reimelt, C., Hackl, C., Grade, M., Buyuktas, D., Siam, L., Balkenhol, M., Stadelmann, C., Kube, D., Krahn, M. P., Proescholdt, M. A., Riemenschneider, M. J., Evert, M., Oefner, Peter J.
, Klein, C. A., Hanisch, U. K., Binder, C. und Pukrop, Tobias
(2019)
LEF1 supports metastatic brain colonization by regulating glutathione metabolism and increasing ROS resistance in breast cancer.
Int. J. Cancer.
Volltext nicht vorhanden.
Singer, Katrin, Dettmer, Katja
, Unger, Petra, Schönhammer, Gabriele, Renner, Kathrin
, Peter, Katrin
, Siska, Peter J.
, Berneburg, Mark
, Herr, Wolfgang, Oefner, Peter J.
, Karrer, Sigrid, Kreutz, Marina
und Datz, Elisabeth
(2019)
Topical Diclofenac Reprograms Metabolism and Immune Cell Infiltration in Actinic Keratosis.
Frontiers in Oncology 2019 (9), S. 605.
Singer, Katrin, Dettmer, Katja
, Unger, Petra, Schoenhammer, Gabriele, Renner, Kathrin, Peter, Katrin, Siska, Peter J., Berneburg, Mark
, Herr, Wolfgang, Oefner, Peter J.
, Karrer, Sigrid, Kreutz, Marina
und Datz, Elisabeth
(2019)
Topical Diclofenac Reprograms Metabolism and Immune Cell Infiltration in Actinic Keratosis.
Front Oncol 9, S. 605.
Hayek, I., Fischer, F., Schulze-Luehrmann, J., Dettmer, Katja
, Sobotta, K., Schatz, V., Kohl, L., Boden, K., Lang, R., Oefner, Peter J.
, Wirtz, S., Jantsch, Jonathan und Luhrmann, A.
(2019)
Limitation of TCA Cycle Intermediates Represents an Oxygen-Independent Nutritional Antibacterial Effector Mechanism of Macrophages.
Cell Rep 26 (13), S. 3502-3510.
Heinrich, Paul, Kohler, Christian
, Ellmann, Lisa, Kuerner, Paul, Spang, Rainer, Oefner, Peter J.
und Dettmer, Katja
(2018)
Correcting for natural isotope abundance and tracer impurity in MS-, MS/MS- and high-resolution-multiple-tracer-data from stable isotope labeling experiments with IsoCorrectoR.
Scientific Reports 8 (17910), S. 1-10.
, Otto, E. A., Milani, M., Broeker, C., Laing, C., Wiesner, J., Devi, S., Zhou, W., Schmitt, R., Tegtmeier, I., Sterner, C., Doellerer, H., Renner, K., Oefner, Peter J.
, Dettmer, Katja
, Simbuerger, J., Witzgall, R., Stanescu, H. C., Dumitriu, S., Iancu, D., Patel, V., Mozere, M., Tekman, M., Jaureguiberry, G., Issler, N., Kesselheim, A., Walsh, S. B., Gale, D. P., Howie, A. J., Martins, J. R., Hall, A. M., Kasgharian, M., O'Brien, K., Ferreira, C. R., Atwal, P. S., Jain, M., Hammers, A., Charles-Edwards, G., Choe, C. U., Isbrandt, D., Cebrian-Serrano, A., Davies, B., Sandford, R. N., Pugh, C., Konecki, D. S., Povey, S., Bockenhauer, D., Lichter-Konecki, U., Gahl, W. A., Unwin, R. J., Warth, Richard
und Kleta, R.
(2018)
Glycine Amidinotransferase (GATM), Renal Fanconi Syndrome, and Kidney Failure.
J. Am. Soc. Nephrol. 29 (7), S. 1849-1858.
Volltext nicht vorhanden.
, Dettmer, Katja
, Vogl, Franziska C., Gronwald, Wolfram, Ellmann, Lisa, Mohney, R. P., Eckardt, K. U., Suhre, K.
, Kastenmüller, Gabi
, Oefner, Peter J. und Köttgen, A.
(2017)
From Discovery to Translation: Characterization of C-Mannosyltryptophan and Pseudouridine as Markers of Kidney Function.
Scientific Reports 7 (1), S. 17400.
Volltext nicht vorhanden.
und Finlay, D. K.
(2017)
Srebp-controlled glucose metabolism is essential for NK cell functional responses.
Nat. Immunol. 18 (11), S. 1197-1206.
Volltext nicht vorhanden.
, Oefner, Peter J. und Gronwald, Wolfram
(2017)
Quantification of metabolites by NMR spectroscopy in the presence of protein.
Journal of Proteome Research 1535-3893.
Volltext nicht vorhanden.
, Laukkanen, K., Vakeva, L., Dettmer, Katja
, Lipsanen, T., Jeskanen, L., Bessede, A., Oefner, Peter J., Kadin, M. E. und Ranki, A.
(2017)
Biological and clinical significance of tryptophan-catabolizing enzymes in cutaneous T-cell lymphomas.
Oncoimmunology 6 (3), e1273310.
Volltext nicht vorhanden.
, Kleo, K., Dimitrova, L., Hummel, M., Feist, M., Kube, D., Szczepanowski, M., Klapper, W., Taruttis, Franziska, Engelmann, Julia C.
, Spang, Rainer, Gronwald, Wolfram und Oefner, Peter J.
(2017)
Comprehensive metaboproteomics of Burkitt's and diffuse large B-cell lymphoma cell lines and primary tumor tissues reveals distinct differences in pyruvate content and metabolism.
Journal of Proteome Research 16, S. 1105-1120.
Volltext nicht vorhanden.
, Taur, Ying, Hiergeist, Andreas
, Koestler, Josef, Dettmer, Katja
, Weber, Markus, Wolff, Daniel, Hahn, Joachim, Pamer, Eric G., Herr, Wolfgang, Gessner, André, Oefner, Peter J., van den Brink, Marcel R. M. und Holler, Ernst
(2017)
Microbiota Disruption Induced by Early Use of Broad-Spectrum Antibiotics Is an Independent Risk Factor of Outcome after Allogeneic Stem Cell Transplantation.
Biology of Blood and Marrow Transplantation 23 (5), S. 845-852.
Volltext nicht vorhanden.
, Fichtner-Feigl, S., Kesselring, R., Mack, M., Ritter, U., Schmid, M., Blank, C., Dettmer, Katja
, Oefner, Peter J., Hoffmann, P., Walenta, S., Geissler, E. K., Pouyssegur, J., Villunger, A., Steven, A.
, Seliger, B., Schreml, S., Haferkamp, S., Kohl, E., Karrer, S., Berneburg, Mark, Herr, Wolfgang, Mueller-Klieser, W., Renner, K. und Kreutz, Marina
(2016)
LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.
Cell Metabolism (Cell Metab.) 24 (5), S. 657-671.
Volltext nicht vorhanden.
und Oefner, Peter J.
(2016)
Evaluation of dilution and normalization strategies to correct for urinary output in HPLC-HRTOFMS metabolomics.
Analytical and Bioanalytical Chemistry (Anal Bioanal Chem).
Volltext nicht vorhanden.
Altenbuchinger, Michael, Rehberg, Thorsten, Zacharias, Helena, Stämmler, Frank, Dettmer, Katja
, Weber, Daniela, Hiergeist, Andreas, Gessner, Andre, Holler, Ernst, Oefner, Peter J. und Spang, Rainer
(2016)
Reference point insensitive molecular data analysis.
Bioinformatics.
Limm, K., Dettmer, Katja
, Reinders, Jörg, Oefner, Peter J. und Bosserhoff, A. K.
(2016)
Characterization of the Methylthioadenosine Phosphorylase Polymorphism rs7023954 - Incidence and Effects on Enzymatic Function in Malignant Melanoma.
PLoS ONE 11 (8), e0160348.
, Tischler, U., Gerthofer, V., Rauer, L., Uhl, M., Proescholdt, M., Bogdahn, U., Riemenschneider, M. J., Oefner, Peter J., Kreutz, M., Vollmann-Zwerenz, A. und Hau, Peter
(2016)
Metformin inhibits proliferation and migration of glioblastoma cells independently of TGF-β2.
Cell Cycle 15 (13), S. 1755-1766.
Volltext nicht vorhanden.
Assmann, Nadine, Dettmer, Katja
, Simbürger, Johann, Broeker, Carsten, Nuernberger, Nadine, Renner, Kathrin, Courtneidge, H., Klootwijk, E. D., Duerkop, Axel
, Hall, A., Kleta, R., Oefner, Peter J.
, Reichold, Markus und Reinders, Jörg
(2016)
Renal Fanconi Syndrome Is Caused by a Mistargeting-Based Mitochondriopathy.
Cell Reports (Cell Rep) 15 (7), S. 1423-1429.
, Oefner, Peter J. und Reinders, Jörg
(2016)
Optimizing the SWATH-MS-workflow for label-free proteomics.
J Proteomics.
Volltext nicht vorhanden.
, Hiergeist, Andreas, Koestler, Josef, Gessner, Andre, Weber, Markus, Stämmler, Frank, Hahn, Joachim, Wolff, Daniel, Herr, Wolfgang und Holler, Ernst
(2016)
Rifaximin preserves intestinal microbiota balance in patients undergoing allogeneic stem cell transplantation.
Bone Marrow Transplant..
Volltext nicht vorhanden.
Voelxen, N. F., Walenta, S., Proescholdt, Martin A., Dettmer, Katja
, Pusch, S.
und Mueller-Klieser, W.
(2016)
Quantitative Imaging of D-2-Hydroxyglutarate in Selected Histological Tissue Areas by a Novel Bioluminescence Technique.
Frontiers in Oncology 6, S. 46.
, Ritter, Axel P., Gottfried, E., Peter, Katrin, Dettmer, Katja
, Oefner, Peter J., Bosserhoff, Anja-Katrin und Kreutz, Marina
(2016)
Suppressive effects of tumor cell-derived 5′-deoxy-5′-methylthioadenosine on human T cells.
OncoImmunology 5, e1184802.
Volltext nicht vorhanden.
Sekula, Peggy
, Goek, Oemer-Necmi, Quaye, Lydia, Barrios, Clara, Levey, Andrew S., Römisch-Margl, Werner, Menni, Cristina
, Yet, Idil, Gieger, Christian, Inker, Lesley A., Adamski, Jerzy, Gronwald, Wolfram, Illig, Thomas, Dettmer, Katja
, Krumsiek, Jan, Oefner, Peter J.
, Valdes, Ana M.
, Meisinger, Christa, Coresh, Josef, Spector, Tim D., Mohney, Robert P., Suhre, Karsten, Kastenmüller, Gabi und Köttgen, Anna
(2015)
A Metabolome-Wide Association Study of Kidney Function and Disease in the General Population.
Journal of the American Society of Nephrology (JASN) 27 (4), S. 1175-1188.
Leisz, Sandra, Schulz, Kristin, Erb, Susanne, Oefner, Peter J.
, Dettmer, Katja
, Mougiakakos, Dimitrios, Wang, Ena, Marincola, Francesco M., Stehle, Franziska und Seliger, Barbara
(2015)
Distinct von Hippel-Lindau gene and hypoxia-regulated alterations in gene and protein expression patterns of renal cell carcinoma and their effects on metabolism.
Oncotarget 6 (13), S. 11395-11406.
und Dettmer, Katja
(2015)
Enhanced metabolite profiling using a redesigned atmospheric pressure chemical ionization source for gas chromatography coupled to high-resolution time-of-flight mass spectrometry.
Anal Bioanal Chem (Analytical and Bioanalytical Chemistry) 407 (22), S. 6669-6680.
Volltext nicht vorhanden.
Jantsch, Jonathan, Schatz, Valentin, Dettmer, Katja
, Dick, Christopher, Ehrenschwender, Martin
, Hellerbrand, Claus und Oefner, Peter J.
(2015)
Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen.
Cell Reports 2015 (13), S. 2048-2055.
Weber, Daniela, Oefner, Peter J.
, Hiergeist, Andreas, Koestler, Josef, Gessner, Andre, Weber, Markus, Hahn, Joachim, Wolff, Daniel, Stämmler, Frank, Spang, Rainer, Herr, Wolfgang, Dettmer, Katja
und Holler, Ernst
(2015)
Low urinary indoxyl sulfate levels early after transplantation reflect a disrupted microbiome and are associated with poor outcome.
Blood 126 (14), S. 1723-1728.
(2014)
Assessment of ionic liquid stationary phases for the GC analysis of fatty acid methyl esters.
Analytical and Bioanalytical Chemistry 406, S. 4931-4939.
Volltext nicht vorhanden.
, Lang, S. A., Mycielska, M. E. und Oefner, Peter J.
(2014)
Continuous water infusion enhances atmospheric pressure chemical ionization of methyl chloroformate derivatives in gas chromatography coupled to time-of-flight mass spectrometry-based metabolomics.
Anal. Chem. 86 (18), S. 9186-9195.
Volltext nicht vorhanden.
, Stevens, Axel Peter, Reinders, Yvonne, Hellerbrand, Claus, Dettmer, Katja
, Gronwald, Wolfram, Oefner, Peter J.
und Reinders, Jörg
(2013)
Changes in the hepatic mitochondrial and membrane proteome in mice fed a non-alcoholic steatohepatitis inducing diet.
Journal of proteomics 80, S. 107-122.
Volltext nicht vorhanden.
Klein, Matthias S.
, Almstetter, Martin F., Nürnberger, Nadine, Sigl, Gregor, Gronwald, Wolfram, Wiedemann, Steffi, Dettmer, Katja
und Oefner, Peter J.
(2013)
Correlations between milk and plasma levels of amino and carboxylic acids in dairy cows.
Journal of Proteome Research 12 (11), S. 5223-5232.
, Vogl, Franziska C., Ritter, Axel P., Zhu, Wentao, Nürnberger, Nadine, Kreutz, Marina, Oefner, Peter J.
, Gronwald, Wolfram und Gottfried, Eva
(2013)
Distinct metabolic differences between various human cancer and primary cells.
ELECTROPHORESIS 34 (19), S. 2836-2847.
Volltext nicht vorhanden.
Czech, Barbara, Dettmer, Katja
, Valletta, Daniela, Saugspier, Michael Sebastian, Koch, Andreas, Stevens, Axel Peter, Thasler, Wolfgang E., Müller, Martina, Oefner, Peter J.
, Bosserhoff, Anja-Katrin
und Hellerbrand, Claus
(2013)
Expression and function of methylthioadenosine phosphorylase in chronic liver disease.
PloS ONE 8 (12), e80703.
, Oefner, Peter J.
, Jachimczak, P., Schneider, A. und Bosserhoff, Anja-Katrin
(2013)
Inducing anti-tumor cytokines and an immune response in melanoma by inhibition of MIA using the peptide AR71.
Eur J Dermatol 23 (6), S. 820-825.
Volltext nicht vorhanden.
Kreutz, Marina, Gottfried, Eva, Lang, Sven A., Renner, Kathrin, Bosserhoff, Anja-Katrin
, Gronwald, Wolfram, Rehli, Michael
, Einhell, Sabine, Gedig, Isabel, Singer, Katrin, Seilbeck, Anton, Mackensen, Andreas, Grauer, Oliver, Hau, Peter, Dettmer, Katja
, Andreesen, Reinhard und Oefner, Peter
(2013)
New aspects of an old drug: Diclofenac targets MYC and glucose metabolism in tumor cells.
PLoS ONE 8 (7), e66987.
und Dettmer, Katja
(2012)
Comprehensive two-dimensional gas chromatography in metabolomics.
Analytical and bioanalytical chemistry 402 (6), S. 1993-2013.
Volltext nicht vorhanden.
, Stevens, A., Dorn, C., Valletta, D., Bosserhoff, A., Oefner, P.J.
und Hellerbrand, C.
(2012)
364 DOWNREGULATION OF METHYLTHIOADENOSINE PHOSPHORYLASE (MTAP) EXPRESSION IN CHRONIC LIVER DISEASE PROMOTES HEPATIC INFLAMMATION AND FIBROSIS.
Journal of Hepatology 56, S147-S148.
Volltext nicht vorhanden.
, Seinstra, Renée I., Dettmer, Katja
, Michels, Helen, Farina, Francesca, Krijnen, Jasper, Melki, Ronald, Buijsman, Rogier C., Ruiz Silva, Mariana, Thijssen, Karen L., Kema, Ido P., Neri, Christian
, Oefner, Peter J.
und Nollen, Ellen A. A.
(2012)
Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation.
Proceedings of the National Academy of Sciences of the United States of America 109 (37), S. 14912-7.
Volltext nicht vorhanden.
, Hellerbrand, Claus, Dettmer, Katja
, Gronwald, Wolfram, Oefner, Peter J.
und Reinders, Jörg
(2012)
Early changes in the liver-soluble proteome from mice fed a nonalcoholic steatohepatitis inducing diet.
Proteomics 12 (9), S. 1437-1451.
Volltext nicht vorhanden.
, Gruber, Michael
und Oefner, Peter J.
(2011)
Comparison of two algorithmic data processing strategies for metabolic fingerprinting by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry.
Journal of chromatography A 1218 (39), S. 7031-7038.
Volltext nicht vorhanden.
, Weiss, Thomas S.
, Wild, Peter, Hartmann, Arndt, Bosserhoff, Anja-Katrin
, Oefner, Peter J.
und Hellerbrand, Claus
(2011)
Down-regulation of methylthioadenosine phosphorylase (MTAP) induces progression of hepatocellular carcinoma via accumulation of 5'-deoxy-5'-methylthioadenosine (MTA).
The American journal of pathology 178 (3), S. 1145-1152.
Volltext nicht vorhanden.
, Dettmer, Katja
und Oefner, Peter J.
(2011)
Improved enantiomer resolution and quantification of free D-amino acids in serum and urine by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry.
Journal of chromatography A 1218 (28), S. 4537-4544.
Volltext nicht vorhanden.
, Nürnberger, Nadine, Kaspar, Hannelore, Gruber, Michael
, Almstetter, Martin F. und Oefner, Peter J.
(2011)
Metabolite extraction from adherently growing mammalian cells for metabolomics studies: optimization of harvesting and extraction protocols.
Analytical and bioanalytical chemistry 399 (3), S. 1127-1139.
Volltext nicht vorhanden.
, Nürnberger, Nadine, Oefner, Peter J.
und Dettmer, Katja
(2011)
Performance evaluation of gas chromatography-atmospheric pressure chemical ionization-time-of-flight mass spectrometry for metabolic fingerprinting and profiling.
Analytical chemistry 83 (19), S. 7514-7322.
Volltext nicht vorhanden.
, Gottfried, Eva, Hoves, Sabine
, Kreutz, Marina, Holler, Ernst, Canelas, André B., Kema, Ido und Oefner, Peter J.
(2011)
Quantitative profiling of tryptophan metabolites in serum, urine, and cell culture supernatants by liquid chromatography-tandem mass spectrometry.
Analytical and bioanalytical chemistry 401 (10), S. 3249-3261.
Volltext nicht vorhanden.
, Gruber, Michael
und Oefner, Peter J.
(2010)
Comparison of derivatization and chromatographic methods for GC-MS analysis of amino acid enantiomers in physiological samples.
Journal of chromatography B 878 (15-16), S. 1103-1112.
Volltext nicht vorhanden.
, Almstetter, Martin F., Appel, Inka, Nürnberger, Nadine, Schlamberger, Gregor, Gronwald, Wolfram, Meyer, Heinrich H. D. und Oefner, Peter J.
(2010)
Comparison of serum versus plasma collection in gas chromatography--mass spectrometry-based metabolomics.
Electrophoresis 31 (14), S. 2365-2373.
Volltext nicht vorhanden.
, Timischl, Birgit, Eberhart, Karin, Dorn, Christoph, Hellerbrand, Claus, Kastenberger, Michael, Kunz-Schughart, Leoni A., Oefner, Peter J.
, Andreesen, Reinhard, Gottfried, Eva und Kreutz, Marina
(2010)
Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes.
Journal of immunology 184 (3), S. 1200-1209.
Volltext nicht vorhanden.
, Almstetter, Martin F., Schlamberger, G., Nürnberger, Nadine, Dettmer, Katja
, Oefner, Peter J.
, Meyer, H. H. D., Wiedemann, Steffi und Gronwald, Wolfram
(2010)
Nuclear magnetic resonance and mass spectrometry-based milk metabolomics in dairy cows during early and late lactation.
Journal of dairy science 93 (4), S. 1539-1550.
Volltext nicht vorhanden.
, Wild, Peter J., Liedtke, Christian
, Mühlbauer, Marcus, Kiefer, Paul, Oefner, Peter J.
, Trautwein, Christian, Bosserhoff, Anja-Katrin
und Hellerbrand, Claus
(2010)
Reduced expression of fibroblast growth factor receptor 2IIIb in hepatocellular carcinoma induces a more aggressive growth.
The American journal of pathology 176 (3), S. 1433-1442.
Volltext nicht vorhanden.
, Dettmer, Katja
und Oefner, Peter J.
(2009)
Capillary electrophoresis and column chromatography in biomedical chiral amino acid analysis.
Analytical and bioanalytical chemistry 394 (3), S. 695-706.
Volltext nicht vorhanden.
, Oefner, Peter J.
und Bosserhoff, Anja-Katrin
(2009)
Direct and tumor microenvironment mediated influences of 5'-deoxy-5'-(methylthio)adenosine on tumor progression of malignant melanoma.
Journal of cellular biochemistry 106 (2), S. 210-219.
Volltext nicht vorhanden.
, Lottaz, Claudio, Timischl, Birgit, Spang, Rainer, Dettmer, Katja
und Oefner, Peter J.
(2009)
Integrative normalization and comparative analysis for metabolic fingerprinting by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry.
Analytical chemistry 81 (14), S. 5731-5739.
Volltext nicht vorhanden.
, Oefner, Peter J.
, Kastenberger, Michael, Kreutz, Marina, Nickl-Jockschat, Thomas
, Bogdahn, Ulrich, Bosserhoff, Anja-Katrin
und Hau, Peter
(2009)
Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2.
Neuro-oncology 11 (4), S. 368-380.
Volltext nicht vorhanden.
, Chan, Queenie
, Daniels, Scott, Nimkar, Subodh, Daviglus, Martha L., Stamler, Jeremiah, Elliott, Paul
und Oefner, Peter J.
(2009)
Urinary amino acid analysis: a comparison of iTRAQ-LC-MS/MS, GC-MS, and amino acid analyzer.
Journal of chromatography B 877 (20-21), S. 1838-1846.
Volltext nicht vorhanden.
, Gronwald, Wolfram und Oefner, Peter J.
(2008)
Automated GC-MS analysis of free amino acids in biological fluids.
J. Chromatogr. B 870 (2), S. 222-232.
Volltext nicht vorhanden.
, Kaspar, H., Thieme, M. und Oefner, Peter J.
(2008)
Development of a quantitative, validated capillary electrophoresis-time of flight-mass spectrometry method with integrated high-confidence analyte identification for metabolomics.
Electrophoresis 29 (10), S. 2203-2214.
Volltext nicht vorhanden.
, Stephensen, C. B. und Hammock, B. D.
(2008)
Metabolic profiling of major vitamin D metabolites using Diels-Alder derivatization and ultra-performance liquid chromatography-tandem mass spectrometry.
Analytical and Bioanalytical Chemistry 391 (5), S. 1917-1930.
Volltext nicht vorhanden.
, Wallner, S., Bosserhoff, Anja-Katrin
und Oefner, Peter J.
(2008)
Quantitative analysis of 5'-deoxy-5'-methylthioadenosine in melanoma cells by liquid chromatography-stable isotope ratio tandem mass spectrometry.
Journal of Chromatography B 876 (1), S. 123-128.
Volltext nicht vorhanden.
, Bertsch, T. und Oefner, Peter J.
(2008)
Urinary metabolite quantification employing 2D NMR spectroscopy.
Anal. Chem. 80 (23), S. 9288-9297.
Volltext nicht vorhanden.
, Hanna, D., Whetstone, P., Hansen, R. und Hammock, B. D.
(2007)
Autism and urinary exogenous neuropeptides: development of an on-line SPE-HPLC-tandem mass spectrometry method to test the opioid excess theory.
Analytical and Bioanalytical Chemistry 388 (8), S. 1643-1651.
Volltext nicht vorhanden.
(2007)
On the occasion of Professor Werner Engewald’s 70th birthday.
Analytical and Bioanalytical Chemistry 388 (8), S. 1631-1632.
Volltext nicht vorhanden.
Fadil, Fadi
, Samol, Claudia, Berger, Raffaela S.
, Kellermeier, Fabian, Gronwald, Wolfram
, Oefner, Peter J.
und Dettmer, Katja
(2023)
Data archive of "Isotope Ratio Outlier Analysis (IROA) for HPLC–TOFMS-Based Metabolomics of Human Urine".
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