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Number of items at this level: 135.

Article

Simeth, Nadja Anita , Kinateder, Thomas , Rajendran, Chitra, Nazet, Julian, Merkl, Rainer , Sterner, Reinhard , König, Burkhard and Kneuttinger, Andrea C. (2020) Towards Photochromic Azobenzene‐Based Inhibitors for Tryptophan Synthase. Chemistry—A European Journal 27, pp. 2439-2451.

Norris, Andrew , Busch, Florian, Schupfner, Michael, Sterner, Reinhard and Wysocki, Vicki H. (2020) Quaternary Structure of the Tryptophan Synthase α-Subunit Homolog BX1 from Zea mays. Journal of the American Society for Mass Spectrometry 31 (2), pp. 227-233. Fulltext not available.

Kneuttinger, Andrea C. , Rajendran, Chitra, Simeth, Nadja A., Bruckmann, Astrid, König, Burkhard and Sterner, Reinhard (2020) Significance of the Protein Interface Configuration for Allostery in Imidazole Glycerol Phosphate Synthase. Biochemistry 59 (29), pp. 2729-2742. Fulltext not available.

Kneuttinger, Andrea C. , Zwisele, Stefanie, Straub, Kristina , Bruckmann, Astrid, Busch, Florian, Kinateder, Thomas, Gaim, Barbara, Wysocki, Vicki H. , Merkl, Rainer and Sterner, Reinhard (2019) Light-Regulation of Tryptophan Synthase by Combining Protein Design and Enzymology. International Journal of Molecular Sciences 20 (20), p. 5106.

Semmelmann, Florian, Hofferberth, John, Ruther, Joachim and Sterner, Reinhard (2019) Mapping key amino acid residues for the epimerase efficiency and stereospecificity of the sex pheromone biosynthetic short-chain dehydrogenases/reductases of Nasonia. Scientific Reports 9 (330), pp. 1-7.

Semmelmann, Florian, Hupfeld, Enrico, Heizinger, Leonhard, Merkl, Rainer and Sterner, Reinhard (2019) A Fold-Independent Interface Residue Is Crucial for Complex Formation and Allosteric Signaling in Class I Glutamine Amidotransferases. Biochemistry 58 (22), pp. 2584-2588. Fulltext not available.

Schupfner, Michael, Straub, Kristina , Busch, Florian, Merkl, Rainer and Sterner, Reinhard (2019) Analysis of allosteric communication in a multienzyme complex by ancestral sequence reconstruction. Proceedings of the National Academy of Sciences 117 (1), pp. 346-354. Fulltext not available.

Semmelmann, Florian, Kabeya, Naoki , Malcicka, Miriama, Bruckmann, Astrid, Broschwitz, Bastian, Straub, Kristina, Merkl, Rainer, Monroig, Oscar, Sterner, Reinhard, Ruther, Joachim and Ellers, Jacintha (2019) Functional characterisation of two Δ12-desaturases demonstrates targeted production of linoleic acid as pheromone precursor in Nasonia. Journal of Experimental Biology. Fulltext not available.

Schupfner, Michael, Busch, Florian, Wysocki, Vicki H. and Sterner, Reinhard (2019) Generation of a Stand‐Alone Tryptophan Synthase α‐Subunit by Mimicking an Evolutionary Blueprint. ChemBioChem 20 (21), pp. 2747-2751. Fulltext not available.

Kneuttinger, Andrea C., Winter, Martin, Simeth, Nadja Anita , Heyn, Kristina, Merkl, Rainer , König, Burkhard and Sterner, Reinhard (2018) Artificial Light Regulation of an Allosteric Bienzyme Complex by a Photosensitive Ligand. ChemBioChem. Fulltext not available.

Fleming, Jennifer R. , Schupfner, Michael, Busch, Florian, Baslé, Arnaud, Ehrmann, Alexander, Sterner, Reinhard and Mayans, Olga (2018) Evolutionary Morphing of Tryptophan Synthase: Functional Mechanisms for the Enzymatic Channeling of Indole. Journal of Molecular Biology 430 (24), pp. 5066-5079. Fulltext not available.

Schlee, Sandra, Klein, Thomas, Schumacher, Magdalena, Nazet, Julian, Merkl, Rainer , Steinhoff, Heinz-Jürgen and Sterner, Reinhard (2018) Relationship of Catalysis and Active Site Loop Dynamics in the (βα)8-Barrel Enzyme Indole-3-glycerol Phosphate Synthase. Biochemistry 57 (23), pp. 3265-3277. Fulltext not available.

Weickhmann, A. Katharina, Keller, Heiko, Wurm, Jan P., Strebitzer, Elisabeth, Juen, Michael A., Kremser, Johannes, Weinberg, Zasha , Kreutz, Christoph , Duchardt-Ferner, Elke and Wöhnert, Jens (2018) The structure of the SAM/SAH-binding riboswitch. Nucleic Acids Research 47 (5), pp. 2654-2665. Fulltext not available.

Merkl, Rainer, Löffler, Patrick , Schmitz, Samuel, Hupfeld, Enrico and Sterner, Reinhard (2017) Rosetta:MSF: a modular framework for multi-state computational protein design. PLOS Computational Biology 13 (6), e1005600.

Sterner, Reinhard, Höcker, Birte and Kolmar, Harald (2017) Highlight issue: protein design. Biological Chemistry 398 (1), pp. 1-2. Fulltext not available.

Simeth, Nadja Anita , Kneuttinger, Andrea C., Sterner, Reinhard and König, Burkhard (2017) Photochromic Coenzyme Q Derivatives: Switching Redox Potentials with Light. Chemical Science 8, pp. 6474-6483.

Ruther, Joachim, Hagström, Asa K., Brandstetter, Birgit, Hofferberth, John, Bruckmann, Astrid, Semmelmann, Florian, Fink, Michaela, Lowack, Helena, Laberer, Sabine, Niehuis, Oliver, Deutzmann, Rainer, Löfstedt, Christer and Sterner, Reinhard (2016) Epimerisation of chiral hydroxylactones by short-chain dehydrogenases/reductases accounts for sex pheromone evolution in Nasonia. Scientific Reports 6 (34697), pp. 1-13.

Merkl, Rainer, Plach, Maximilian G., Reisinger, Bernd and Sterner, Reinhard (2016) Long-Term Persistence of Bi-functionality Contributes to the Robustness of Microbial Life through Exaptation. PLoS Genetics 12 (1), pp. 1-14.

Busch, Florian, Rajendran, Chitra, Heyn, Kristina, Schlee, Sandra, Merkl, Rainer and Sterner, Reinhard (2016) Ancestral Tryptophan Synthase Reveals Functional Sophistication of Primordial Enzyme Complexes. Cell Chemical Biology 23 (6), pp. 709-715. Fulltext not available.

Reisinger, Bernd, Kuzmanovic, Natascha, Löffler, Patrick, Merkl, Rainer, König, Burkhard and Sterner, Reinhard (2014) Exploiting Protein Symmetry To Design Light-Controllable Enzyme Inhibitors. Angewandte Chemie International Edition 53, pp. 595-598. Fulltext not available.

Seitz, Tobias, Thoma, Ralf, Schoch, Guillaume A., Stihle, Martine, Benz, Jörg, D'Arcy, Brigitte, Wiget, Andrea, Ruf, Armin, Hennig, Michael and Sterner, Reinhard (2010) Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening. Journal of molecular biology 403 (4), pp. 562-577. Fulltext not available.

Drzewiecki, Katharina, Angelov, Angel, Ballschmiter, Meike, Tiefenbach, Klaus-Jürgen, Sterner, Reinhard and Liebl, Wolfgang (2010) Hyperthermostable acetyl xylan esterase. Microbial biotechnology 3 (1), pp. 84-92. Fulltext not available.

Ehrmann, Alexander, Richter, Klaus, Busch, Florian, Reimann, Julia, Albers, Sonja-Verena and Sterner, Reinhard (2010) Ligand-induced formation of a transient tryptophan synthase complex with aßß subunit stoichiometry. Biochemistry (49), pp. 10842-10853. Fulltext not available.

Liebold, Christoph, List, Felix, Kalbitzer, Hans Robert, Sterner, Reinhard and Brunner, Eike (2010) The interaction of ammonia and xenon with the imidazole glycerol phosphate synthase from Thermotoga maritima as detected by NMR spectroscopy. Protein science : a publication of the Protein Society 19 (9), pp. 1774-1782. Fulltext not available.

Schlee, Sandra, Deuss, Miriam, Bruning, Marc, Ivens, Andreas, Schwab, Thomas, Hellmann, Nadja, Mayans, Olga and Sterner, Reinhard (2009) Activation of anthranilate phosphoribosyltransferase from Sulfolobus solfataricus by removal of magnesium inhibition and acceleration of product release. Biochemistry 48 (23), pp. 5199-209. Fulltext not available.

Claren, Jörg, Malisi, Christoph, Höcker, Birte and Sterner, Reinhard (2009) Establishing wild-type levels of catalytic activity on natural and artificial (beta alpha)8-barrel protein scaffolds. Proceedings of the National Academy of Sciences of the United States of America 106 (10), pp. 3704-9. Fulltext not available.

Xiang, Dao Feng, Kolb, Peter, Fedorov, Alexander A., Meier, Monika M., Fedorov, Lena V., Nguyen, T. Tinh, Sterner, Reinhard, Almo, Steven C., Shoichet, Brian K. and Raushel, Frank M. (2009) Functional annotation and three-dimensional structure of Dr0930 from Deinococcus radiodurans, a close relative of phosphotriesterase in the amidohydrolase superfamily. Biochemistry 48 (10), pp. 2237-47. Fulltext not available.

Höcker, Birte, Lochner, Adriane, Seitz, Tobias, Claren, Jörg and Sterner, Reinhard (2009) High-resolution crystal structure of an artificial (betaalpha)(8)-barrel protein designed from identical half-barrels. Biochemistry 48 (6), pp. 1145-7. Fulltext not available.

Fischer, André, Enkler, Nils, Neudert, Gerd, Bocola, Marco, Sterner, Reinhard and Merkl, Rainer (2009) TransCent: computational enzyme design by transferring active sites and considering constraints relevant for catalysis. BMC Bioinformatics 10, p. 54.

Schwab, Thomas, Skegro, Darko, Mayans, Olga and Sterner, Reinhard (2008) A rationally designed monomeric variant of anthranilate phosphoribosyltransferase from Sulfolobus solfataricus is as active as the dimeric wild-type enzyme but less thermostable. Journal of molecular biology 376 (2), pp. 506-16. Fulltext not available.

Reetz, Manfred T., Rentzsch, Martin, Pletsch, Andreas, Taglieber, Andreas, Hollmann, Frank, Mondière, Régis J. G., Dickmann, Norbert, Höcker, Birte, Cerrone, Simona, Haeger, Michaela C. and Sterner, Reinhard (2008) A robust protein host for anchoring chelating ligands and organocatalysts. Chembiochem : a European journal of chemical biology 9 (4), pp. 552-64. Fulltext not available.

Sterner, Reinhard, Merkl, Rainer and Raushel, Frank M. (2008) Computational design of enzymes. Chemistry & Biology 15 (5), pp. 421-423. Fulltext not available.

Sterner, Reinhard, Merkl, Rainer and Raushel, Frank M. (2008) Computational design of enzymes. Chemistry & biology 15 (5), pp. 421-3. Fulltext not available.

Guldan, Harald, Sterner, Reinhard and Babinger, Patrick (2008) Identification and characterization of a bacterial glycerol-1-phosphate dehydrogenase: Ni(2+)-dependent AraM from Bacillus subtilis. Biochemistry 47 (28), pp. 7376-84. Fulltext not available.

Seitz, Tobias, Bocola, Marco, Claren, Jörg and Sterner, Reinhard (2007) Stabilisation of a (betaalpha)8-barrel protein designed from identical half barrels. Journal of molecular biology 372 (1), pp. 114-29. Fulltext not available.

Leopoldseder, Sonja, Hettwer, Stefan and Sterner, Reinhard (2006) Evolution of multi-enzyme complexes: the case of tryptophan synthase. Biochemistry 45 (47), pp. 14111-9. Fulltext not available.

Sterner, Reinhard and Höcker, Birte (2005) Catalytic versatility, stability, and evolution of the (betaalpha)8-barrel enzyme fold. Chemical reviews 105 (11), pp. 4038-55. Fulltext not available.

Vega, M. Cristina, Zou, Peijian, Fernandez, Francisco J., Murphy, Gavin E., Sterner, Reinhard, Popov, Alexander and Wilmanns, Matthias (2005) Regulation of the hetero-octameric ATP phosphoribosyl transferase complex from Thermotoga maritima by a tRNA synthetase-like subunit. Molecular microbiology 55 (3), pp. 675-86. Fulltext not available.

Schneider, Birgit, Knöchel, Thorsten, Darimont, Beatrice, Hennig, Michael, Dietrich, Susanne, Babinger, Karin, Kirschner, Kasper and Sterner, Reinhard (2005) Role of the N-terminal extension of the (betaalpha)8-barrel enzyme indole-3-glycerol phosphate synthase for its fold, stability, and catalytic activity. Biochemistry 44 (50), pp. 16405-12. Fulltext not available.

Sterner, Reinhard and Schmid, Franz X. (2004) Biochemistry. De novo design of an enzyme. Science (New York, N.Y.) 304 (5679), pp. 1916-7. Fulltext not available.

Thiemann, Volker, Dönges, Catharina, Prowe, Steffen G., Sterner, Reinhard and Antranikian, Garabed (2004) Characterisation of a thermoalkali-stable cyclodextrin glycosyltransferase from the anaerobic thermoalkaliphilic bacterium Anaerobranca gottschalkii. Archives of microbiology 182 (2-3), pp. 226-35. Fulltext not available.

Leopoldseder, Sonja, Claren, Jörg, Jürgens, Catharina and Sterner, Reinhard (2004) Interconverting the catalytic activities of (betaalpha)(8)-barrel enzymes from different metabolic pathways: sequence requirements and molecular analysis. Journal of molecular biology 337 (4), pp. 871-9. Fulltext not available.

Höcker, Birte, Claren, Jörg and Sterner, Reinhard (2004) Mimicking enzyme evolution by generating new (betaalpha)8-barrels from (betaalpha)4-half-barrels. Proceedings of the National Academy of Sciences of the United States of America 101 (47), pp. 16448-53. Fulltext not available.

Jaenicke, Rainer and Sterner, Reinhard (2003) Protein design at the crossroads of biotechnology, chemistry, theory, and evolution. Angewandte Chemie (International ed. in English) 42 (2), pp. 140-2. Fulltext not available.

Höcker, Birte, Schmidt, Steffen and Sterner, Reinhard (2002) A common evolutionary origin of two elementary enzyme folds. FEBS letters 510 (3), pp. 133-5. Fulltext not available.

Hettwer, Stefan and Sterner, Reinhard (2002) A novel tryptophan synthase beta-subunit from the hyperthermophile Thermotoga maritima. Quaternary structure, steady-state kinetics, and putative physiological role. The Journal of biological chemistry 277 (10), pp. 8194-201. Fulltext not available.

Douangamath, Alice, Walker, Martina, Beismann-Driemeyer, Silke, Vega-Fernandez, M. Cristina, Sterner, Reinhard and Wilmanns, Matthias (2002) Structural evidence for ammonia tunneling across the (beta alpha)(8) barrel of the imidazole glycerol phosphate synthase bienzyme complex. Structure (London, England : 1993) 10 (2), pp. 185-93. Fulltext not available.

Henn-Sax, Martina, Thoma, Ralf, Schmidt, Steffen, Hennig, Michael, Kirschner, Kasper and Sterner, Reinhard (2002) Two (betaalpha)(8)-barrel enzymes of histidine and tryptophan biosynthesis have similar reaction mechanisms and common strategies for protecting their labile substrates. Biochemistry 41 (40), pp. 12032-42. Fulltext not available.

Höcker, Birte, Beismann-Driemeyer, Silke, Hettwer, Stefan, Lustig, A. and Sterner, Reinhard (2001) Dissection of a (betaalpha)8-barrel enzyme into two folded halves. Nature structural biology 8 (1), pp. 32-6. Fulltext not available.

Henn-Sax, Martina, Höcker, Birte, Wilmanns, Matthias and Sterner, Reinhard (2001) Divergent evolution of (betaalpha)8-barrel enzymes. Biological chemistry 382 (9), pp. 1315-20. Fulltext not available.

Sterner, Reinhard (2001) Ferredoxin from Thermotoga maritima. Methods in enzymology 334, pp. 23-30. Fulltext not available.

Beismann-Driemeyer, Silke and Sterner, Reinhard (2001) Imidazole glycerol phosphate synthase from Thermotoga maritima. Quaternary structure, steady-state kinetics, and reaction mechanism of the bienzyme complex. The Journal of biological chemistry 276 (23), pp. 20387-96. Fulltext not available.

Sterner, Reinhard, Merz, A., Thoma, Ralf and Kirschner, Kasper (2001) Phosphoribosylanthranilate isomerase and indoleglycerol-phosphate synthase: tryptophan biosynthetic enzymes from Thermotoga maritima. Methods in enzymology 331, pp. 270-80. Fulltext not available.

Höcker, Birte, Jürgens, Catharina, Wilmanns, Matthias and Sterner, Reinhard (2001) Stability, catalytic versatility and evolution of the (beta alpha)(8)-barrel fold. Current opinion in biotechnology 12 (4), pp. 376-81. Fulltext not available.

Sterner, Reinhard and Liebl, W. (2001) Thermophilic adaptation of proteins. Critical reviews in biochemistry and molecular biology 36 (1), pp. 39-106. Fulltext not available.

Jürgens, Catharina, Strom, A., Wegener, D., Hettwer, Stefan, Wilmanns, Matthias and Sterner, Reinhard (2000) Directed evolution of a (beta alpha)8-barrel enzyme to catalyze related reactions in two different metabolic pathways. Proceedings of the National Academy of Sciences of the United States of America 97 (18), pp. 9925-30. Fulltext not available.

Lang, Detlef, Thoma, Ralf, Henn-Sax, Martina, Sterner, Reinhard and Wilmanns, Matthias (2000) Structural evidence for evolution of the beta/alpha barrel scaffold by gene duplication and fusion. Science (New York, N.Y.) 289 (5484), pp. 1546-50. Fulltext not available.

Thoma, Ralf, Hennig, Michael, Sterner, Reinhard and Kirschner, Kasper (2000) Structure and function of mutationally generated monomers of dimeric phosphoribosylanthranilate isomerase from Thermotoga maritima. Structure (London, England : 1993) 8 (3), pp. 265-76. Fulltext not available.

Thoma, Ralf, Obmolova, G., Lang, D. A., Schwander, M., Jenö, P., Sterner, Reinhard and Wilmanns, Matthias (1999) Efficient expression, purification and crystallisation of two hyperthermostable enzymes of histidine biosynthesis. FEBS letters 454 (1-2), pp. 1-6. Fulltext not available.

Thoma, Ralf, Schwander, M., Liebl, W., Kirschner, Kasper and Sterner, Reinhard (1998) A histidine gene cluster of the hyperthermophile Thermotoga maritima: sequence analysis and evolutionary significance. Extremophiles : life under extreme conditions 2 (4), pp. 379-89. Fulltext not available.

Hennig, Michael, Sterner, Reinhard, Kirschner, Kasper and Jansonius, J. N. (1997) Crystal structure at 2.0 A resolution of phosphoribosyl anthranilate isomerase from the hyperthermophile Thermotoga maritima: possible determinants of protein stability. Biochemistry 36 (20), pp. 6009-16. Fulltext not available.

Pfeil, W., Gesierich, U., Kleemann, G. R. and Sterner, Reinhard (1997) Ferredoxin from the hyperthermophile Thermotoga maritima is stable beyond the boiling point of water. Journal of molecular biology 272 (4), pp. 591-6. Fulltext not available.

Macedo-Ribeiro, S., Darimont, Beatrice and Sterner, Reinhard (1997) Structural features correlated with the extreme thermostability of 1[4Fe-4S] ferredoxin from the hyperthermophilic bacterium Thermotoga maritima. Biological chemistry 378 (3-4), pp. 331-6. Fulltext not available.

Sticht, H., Wildegger, G., Bentrop, D., Darimont, Beatrice, Sterner, Reinhard and Rösch, P. (1996) An NMR-derived model for the solution structure of oxidized Thermotoga maritima 1[Fe4-S4] ferredoxin. European journal of biochemistry / FEBS 237 (3), pp. 726-35. Fulltext not available.

Sterner, Reinhard, Kleemann, G. R., Szadkowski, H., Lustig, A., Hennig, Michael and Kirschner, Kasper (1996) Phosphoribosyl anthranilate isomerase from Thermotoga maritima is an extremely stable and active homodimer. Protein science : a publication of the Protein Society 5 (10), pp. 2000-8. Fulltext not available.

Macedo-Ribeiro, S., Darimont, Beatrice, Sterner, Reinhard and Huber, R. (1996) Small structural changes account for the high thermostability of 1[4Fe-4S] ferredoxin from the hyperthermophilic bacterium Thermotoga maritima. Structure (London, England : 1993) 4 (11), pp. 1291-301. Fulltext not available.

Decker, H., Hartmann, H., Sterner, Reinhard, Schwarz, E. and Pilz, I. (1996) Small-angle X-ray scattering reveals differences between the quaternary structures of oxygenated and deoxygenated tarantula hemocyanin. FEBS letters 393 (2-3), pp. 226-30. Fulltext not available.

Sterner, Reinhard, Dahm, A., Darimont, Beatrice, Ivens, Andreas, Liebl, W. and Kirschner, Kasper (1995) (Beta alpha)8-barrel proteins of tryptophan biosynthesis in the hyperthermophile Thermotoga maritima. The EMBO journal 14 (18), pp. 4395-402. Fulltext not available.

Wildegger, G., Bentrop, D., Ejchart, A., Alber, M., Hage, A., Sterner, Reinhard and Rösch, P. (1995) 1H nuclear-magnetic-resonance investigation of oxidized Fe4S4 ferredoxin from Thermotoga maritima. Hyperfine-shifted resonances, sequence-specific assignments and secondary structure. European journal of biochemistry / FEBS 229 (3), pp. 658-68. Fulltext not available.

Hennig, Michael, Darimont, Beatrice, Sterner, Reinhard, Kirschner, Kasper and Jansonius, J. N. (1995) 2.0 A structure of indole-3-glycerol phosphate synthase from the hyperthermophile Sulfolobus solfataricus: possible determinants of protein stability. Structure (London, England : 1993) 3 (12), pp. 1295-306. Fulltext not available.

Sterner, Reinhard, Vogl, T., Hinz, H. J., Penz, F., Hoff, R., Föll, R. and Decker, H. (1995) Extreme thermostability of tarantula hemocyanin. FEBS letters 364 (1), pp. 9-12. Fulltext not available.

Sterner, Reinhard and Decker, H. (1994) Inversion of the Bohr effect upon oxygen binding to 24-meric tarantula hemocyanin. Proceedings of the National Academy of Sciences of the United States of America 91 (11), pp. 4835-9. Fulltext not available.

Darimont, Beatrice and Sterner, Reinhard (1994) Sequence, assembly and evolution of a primordial ferredoxin from Thermotoga maritima. The EMBO journal 13 (8), pp. 1772-81. Fulltext not available.

Sterner, Reinhard, Bardehle, K., Paul, R. and Decker, H. (1994) Tris: an allosteric effector of tarantula haemocyanin. FEBS letters 339 (1-2), pp. 37-9. Fulltext not available.

Decker, H. and Sterner, Reinhard (1990) Nested allostery of arthropodan hemocyanin (Eurypelma californicum and Homarus americanus). The role of protons. Journal of molecular biology 211 (1), pp. 281-93. Fulltext not available.

Decker, H. and Sterner, Reinhard (1990) [Hierarchies in the structure and function of oxygen-binding proteins]. Die Naturwissenschaften 77 (12), pp. 561-8. Fulltext not available.

Thesis of the University of Regensburg

Hupfeld, Enrico (2021) Linkage between catalytic mechanism and conformational dynamics in (βα)₈-barrel enzymes at the example of Imidazole Glycerol Phosphate Synthase. PhD, Universität Regensburg.

Semmelmannn, Florian (2019) Analysis of Allosteric Communication Pathways in Class I Glutamine Amidotransferases. PhD, Universität Regensburg.

Schupfner, Michael (2019) Analysis of Allostery in the Tryptophan Synthase Complex by Horizontal and Vertical Approaches. PhD, Universität Regensburg.

Straub, Kristina (2019) Ancestral Sequence Reconstruction: Methods and Applications. PhD, Universität Regensburg.

Killian, Tobias Friedrich (2019) Development, characterization and synthesis of multi-specific proteins for targeted delivery of nucleic acids and nucleic acid derivatives. PhD, Universität Regensburg.

Kaiser, Wolfgang (2018) Biochemische Charakterisierung des YbiB-Proteins aus Escherichia coli und dessen Identifizierung als Nukleotidpyrophosphatase. PhD, Universität Regensburg.

Fischer, Robert Andreas (2017) Untersuchung von Mykobakteriophagen-Lysinen als antimykobakterielle Wirkstoffe. PhD, Universität Regensburg.

Linde, Mona (2017) Characterization of Enzymes Involved in the Synthesis and Processing of Ether Lipids in Archaea and Bacteria. PhD, Universität Regensburg.

Plach, Maximilian (2017) Evolution of substrate specificity and protein-protein interactions in three enzyme superfamilies. PhD, Universität Regensburg.

Holinski, Alexandra (2017) Analysis of complex stability and allosteric interaction in the imidazole glycerol phosphate synthase complex. PhD, Universität Regensburg.

Busch, Florian (2016) Tryptophan synthase complexes: evolution, substrate specificity, and quaternary structure. PhD, Universität Regensburg.

Peterhoff, David (2014) Systematic structural and functional characterization of the family of Geranylgeranylglyceryl Phosphate Synthase-like enzymes. PhD, Universität Regensburg.

Reisinger, Bernd (2014) Mechanistic investigation of artificially designed, light regulation of naturally occurring, and characterization of ancestral (βα)8-barrel enzymes. PhD, Universität Regensburg.

Meier, Monika M. (2013) Reconstructing molecular evolution by changing substrate specificities within the amidohydrolase superfamily of enzymes. PhD, Universität Regensburg.

Sperl, Josef (2013) Etablierung von enzymatischer Aktivität auf künstlich erzeugten (βα)8-Barrel Proteinen. PhD, Universität Regensburg.

Schneider, Daniel (2013) Identifikation und funktionelle Charakterisierung von TrpD2, einer neuen Klasse nukleinsäurebindender Proteine. PhD, Universität Regensburg.

Carstensen, Linn (2012) Conservation of the folding mechanism between a thermostable (βα)8-barrel enzyme, its evolutionary relatives, and ancestral precursors generated by protein design. PhD, Universität Regensburg.

Scherzinger, Anna Sophie (2012) Entwicklung einer Methode der zufälligen Domänenkombination zur Optimierung von Peptidoglykan-Hydrolasen für die Anwendung im Lebensmittel am Beispiel von Listeria spp. mit anschließender Charakterisierung ausgewählter Proteine. PhD, Universität Regensburg.

Guldan, Harald (2011) Nachweis Archaea-typischer Lipide in Bacteria über die Aufklärung der Funktion von AraM und PcrB aus Bacillus subtilis. PhD, Universität Regensburg.

Dietrich, Susanne (2011) Mutationsanalyse und kinetische Untersuchungen zum Reaktionsmechanismus der Indolglycerinphosphat-Synthase aus Sulfolobus solfataricus. PhD, Universität Regensburg.

Seitz, Tobias (2011) Erhöhung der Löslichkeit und Stabilität verschiedener Proteine durch rationales Design und gelenkte Evolution. PhD, Universität Regensburg.

Ehrmann, Alexander (2011) Strukturelle Analyse neuartiger Tryptophan-Synthasen und funktionelle Charakterisierung ihrer Homologen. PhD, Universität Regensburg.

Claren, Jörg (2009) Design stabiler und katalytisch aktiver (beta, alpha)8-Barrel-Enzyme durch Rekombination von (beta, alpha)4-Halbbarrel-Domänen. PhD, Universität Regensburg.

Richter, Markus (2009) Untersuchungen zur Evolution der (beta/alpha)8-barrel Faltung aus (beta/alpha)2-Modulen. PhD, Universität Regensburg.

Forchheim, Michael (2009) Isolierung und Optimierung antimikrobiell wirkender Phagenproteine zur Bekämpfung antibiotikaresistenter Staphylokokken. PhD, Universität Regensburg.

Fischer, André (2008) TRANSCENT - ein Enzymdesignprogramm zum Transfer aktiver Zentren unter Wahrung Katalyse-relevanter Rahmenbedingungen. PhD, Universität Regensburg.

Deuß, Miriam (2007) Untersuchungen zur Struktur, Funktion und Dynamik der Anthranilat-Phosphoribosyltransferase aus Sulfolobus solfataricus. PhD, Universität Regensburg.

Häger, Michaela C. (2006) Evolution und Regulation von Protein-Protein Interaktionen in zwei Glutamin-Amidotransferasen aus der Biosynthese von Histidin und Tryptophan. PhD, Universität Regensburg.

Giesecke, Astrid (2006) Protein-protein interactions mediated by Cys2His2 zinc-fingers. PhD, Universität Regensburg.

Leopoldseder, Sonja (2006) Neuartige Tryptophan-Synthasen aus Hyperthermophilen: Charakterisierung der Enzyme aus Sulfolobus solfataricus. PhD, Universität Regensburg.

Thesis

Burghardt, Kathleen (2010) Aktivierung einer thermostabilen Anthranilat-Phosphoribosyltransferase durch gerichtete Evolution. Diplomarbeit, Universität Regensburg. Fulltext not available.

Borst, Nadine (2010) Experimentelle Validierung von durch bioinformatische Korrelationsanalysen identifizierten Aminosäurepositionen. Diplomarbeit, UNSPECIFIED. Fulltext not available.

Busch, Florian (2010) Funktionsaufklärung des zur Tryptophansynthese homologen Enzyms sTrpBs2. Diplomarbeit, UNSPECIFIED. Fulltext not available.

Dietrich, Susanne (2010) Mutationsanalyse und kinetische Untersuchungen zum Reaktionsmechanismus der Indolglycerinphosphat-Synthase aus Sulfolobus solfataricus. PhD, Universität Regensburg. Fulltext not available.

Sommer, Bettina (2009) Aktivierung einer chimären RNA-Polymerase Untereinheit durch gerichtete Evoluton. Diplomarbeit, Universität Regensburg. Fulltext not available.

Sperl, Josef (2009) Analyse der Faltung und Erhöhung der Stabilität künstlich erzeugter (βα)₈-Barrel Proteine. Diplomarbeit, Universität Regensburg. Fulltext not available.

List, Felix (2009) Die Imidazolglycerinphosphat-Synthase aus Thermotoga Maritima: Struktur, Regulation und Evolution einer Glutaminamidotransferase. PhD, Universität Regensburg. Fulltext not available.

Roderer, Daniel (2009) Die Suche nach Interaktionspartnern des uncharakterisierten E.coli -Proteins YbiB. Diplomarbeit, Universität Regensburg. Fulltext not available.

Esslinger, Ulrike (2009) Die uncharakterisierte Proteingruppe COG0325: Funktionsaufklärung und Suche nach Interaktionspartnern. Diplomarbeit, Universität Regensburg. Fulltext not available.

Peterhoff, David (2009) Einbau nichtnatürlicher Aminosäuren zur Untersuchung der Dimerisierung von PcrB. Diplomarbeit, Universität Regensburg. Fulltext not available.

Reisinger, Bernd (2009) Experimentelle Charakterisierung bzw. Verbesserung von rational designten (βα)₈-Barrel Proteinen aus dem Histidinbiosyntheseweg. Diplomarbeit, Universität Regensburg. Fulltext not available.

Meier, Monika (2008) Interconversion of Substrate Specificity within the Amidohydrolase Superfamily of Enzymes. Diplomarbeit, Universität Regensburg. Fulltext not available.

Lochner, Adriane (2008) Stabilisierung und Aktivierung eines künstlichen (βα)₈ Fass Proteins. Diplomarbeit, Universität Regensburg. Fulltext not available.

Guldan, Harald (2007) Charakterisierung der sn-Glycerin-1-Phosphat-abhängigen Enzyme AraM und PcrB aus Bacillus subtilis. Diplomarbeit, Universität Regensburg. Fulltext not available.

Schneider, Daniel (2007) Charakterisierung von ybiB, einer putativen Phosphoribosyltransferase aus Escherichia coli. Diplomarbeit, Universität Regensburg. Fulltext not available.

Schwabe, Anne (2007) Mutationsanalysen der Komplexbildung von Tryptophan-Synthasen aus Thermotoga maritima. Diplomarbeit, Universität Regensburg. Fulltext not available.

Zwick, Matthias (2007) Rekombinante Expression der Bacillus subtilis Gene pabA, pabB und trpE und Charakterisierung der Komplexbildung der Genprodukte. Diplomarbeit, Universität Regensburg. Fulltext not available.

Einhell, Sabine (2007) Stabilisierung von Noc4D6-8 aus Saccharomyces cerevisiae durch gerichtete Evolution. Diplomarbeit, Universität Regensburg. Fulltext not available.

Plank, Maximilian (2007) Untersuchungen zu einer uncharakterisierten Proteingruppe mit (βα)₈-Faß Struktur: COG0325. Diplomarbeit, Universität Regensburg. Fulltext not available.

Schwab, Thomas (2006) Monomerisierung einer thermostabilen Anthranilat Phosphoribosyltransferase aus Sulfolobus solfataricus durch Proteindesign. Diplomarbeit, Universität Regensburg. Fulltext not available.

Bolz, Christian (2006) Mutationsanalyse zur Identifizierung der strukturellen Grundlage einer spezifischen Protein-Protein Interaktion. Diplomarbeit, Universität Regensburg. Fulltext not available.

Dumm, Bernhard (2006) Optimierung der Fremdaktivität eines (βα)₈-Barrel Enzyms aus der Histidinbiosynthese. Diplomarbeit, Universität Regensburg. Fulltext not available.

Seitz, Tobias (2006) Stabilisierung eines künstlich erzeugten (βα)₈-Barrel Proteins durch gelenkte Evolution. Diplomarbeit, Universität Regensburg. Fulltext not available.

Riede, Philipp (2006) Versuch der Etablierung einer neuen katalytischen Aktivität auf dem Proteingerüst der Indolglycerolphosphat Synthase aus Sulfolobus solfataricus. Diplomarbeit, Universität Regensburg. Fulltext not available.

Marquardt, Susanne (2005) Biochemische Charakterisierung der ATP-Phosphoribosyltransferase (His(GSZ)₄-Komplex) aus Thermotoga maritima. Diplomarbeit, Universität Regensburg. Fulltext not available.

Dietrich, Susanne (2005) Enzymkinetische Untersuchungen zur evolutionären Verwandtschaft der Indolglycerolphosphat Synthase mit der α-Untereinheit der Tryptophan Synthase. Diplomarbeit, Universität Regensburg. Fulltext not available.

List, Felix (2005) Protein-Protein Wechselwirkungen innerhalb der Anthranilat Synthase aus Thermotoga maritima. Diplomarbeit, Universität Regensburg. Fulltext not available.

Lambeck, Iris (2004) Arbeiten zur Umwandlung der Tryptophansynthase α-Untereinheit aus Thermotoga maritima in eine Triosephosphatisomerase. Diplomarbeit, Universität Regensburg. Fulltext not available.

Schneider, Birgit (2004) Die Rolle der N-terminalen Helix α0 in dem (βα)₈-Barrel Indolglycerolphosphat Synthase aus Thermotoga maritima und Sulfolobus solfataricus. Diplomarbeit, Universität Regensburg. Fulltext not available.

This list was generated on Tue Dec 6 11:10:06 2022 CET.
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