Anzahl der Einträge in dieser Kategorie: 168.
Bhagat, Ashok Kumar,
Schlee, Sandra,
Straub, Kristina,
Nazet, Julian,
Luckner, Patricia,
Bruckmann, Astrid und
Sterner, Reinhard
(2022)
Photoswitching of Feedback Inhibition by Tryptophan in Anthranilate Synthase.
ACS Synthetic Biology 11 (8), S. 2846-2856.
Volltext nicht vorhanden.
Hertle, Regina,
Nazet, Julian,
Semmelmann, Florian,
Schlee, Sandra,
Funke, Franziska,
Merkl, Rainer und
Sterner, Reinhard
(2021)
Reprogramming the Specificity of a Protein Interface by Computational and Data-Driven Design.
Structure 29 (3), 292-304.e3.
Volltext nicht vorhanden.
Simeth, Nadja Anita ,
Kinateder, Thomas,
Rajendran, Chitra,
Nazet, Julian,
Merkl, Rainer ,
Sterner, Reinhard ,
König, Burkhard und
Kneuttinger, Andrea C.
(2020)
Towards Photochromic Azobenzene‐Based Inhibitors for Tryptophan Synthase.
Chemistry—A European Journal 27, S. 2439-2451.
Kneuttinger, Andrea C. ,
Rajendran, Chitra,
Simeth, Nadja A.,
Bruckmann, Astrid,
König, Burkhard und
Sterner, Reinhard
(2020)
Significance of the Protein Interface Configuration for Allostery in Imidazole Glycerol Phosphate Synthase.
Biochemistry 59 (29), S. 2729-2742.
Volltext nicht vorhanden.
Kneuttinger, Andrea C. ,
Zwisele, Stefanie,
Straub, Kristina ,
Bruckmann, Astrid,
Busch, Florian,
Kinateder, Thomas,
Gaim, Barbara,
Wysocki, Vicki H. ,
Merkl, Rainer und
Sterner, Reinhard
(2019)
Light-Regulation of Tryptophan Synthase by Combining Protein Design and Enzymology.
International Journal of Molecular Sciences 20 (20), S. 5106.
Semmelmann, Florian,
Kabeya, Naoki ,
Malcicka, Miriama,
Bruckmann, Astrid,
Broschwitz, Bastian,
Straub, Kristina,
Merkl, Rainer,
Monroig, Oscar,
Sterner, Reinhard,
Ruther, Joachim und
Ellers, Jacintha
(2019)
Functional characterisation of two Δ12-desaturases demonstrates targeted production of linoleic acid as pheromone precursor in Nasonia.
Journal of Experimental Biology.
Volltext nicht vorhanden.
Kneuttinger, Andrea C.,
Winter, Martin,
Simeth, Nadja Anita ,
Heyn, Kristina,
Merkl, Rainer ,
König, Burkhard und
Sterner, Reinhard
(2018)
Artificial Light Regulation of an Allosteric Bienzyme Complex by a Photosensitive Ligand.
ChemBioChem.
Volltext nicht vorhanden.
Fleming, Jennifer R. ,
Schupfner, Michael,
Busch, Florian,
Baslé, Arnaud,
Ehrmann, Alexander,
Sterner, Reinhard und
Mayans, Olga
(2018)
Evolutionary Morphing of Tryptophan Synthase: Functional Mechanisms for the Enzymatic Channeling of Indole.
Journal of Molecular Biology 430 (24), S. 5066-5079.
Volltext nicht vorhanden.
Schlee, Sandra,
Klein, Thomas,
Schumacher, Magdalena,
Nazet, Julian,
Merkl, Rainer ,
Steinhoff, Heinz-Jürgen und
Sterner, Reinhard
(2018)
Relationship of Catalysis and Active Site Loop Dynamics in the (βα)8-Barrel Enzyme Indole-3-glycerol Phosphate Synthase.
Biochemistry 57 (23), S. 3265-3277.
Volltext nicht vorhanden.
Weickhmann, A. Katharina,
Keller, Heiko,
Wurm, Jan P.,
Strebitzer, Elisabeth,
Juen, Michael A.,
Kremser, Johannes,
Weinberg, Zasha ,
Kreutz, Christoph ,
Duchardt-Ferner, Elke und
Wöhnert, Jens
(2018)
The structure of the SAM/SAH-binding riboswitch.
Nucleic Acids Research 47 (5), S. 2654-2665.
Volltext nicht vorhanden.
Ruther, Joachim,
Hagström, Asa K.,
Brandstetter, Birgit,
Hofferberth, John,
Bruckmann, Astrid,
Semmelmann, Florian,
Fink, Michaela,
Lowack, Helena,
Laberer, Sabine,
Niehuis, Oliver,
Deutzmann, Rainer,
Löfstedt, Christer und
Sterner, Reinhard
(2016)
Epimerisation of chiral hydroxylactones by short-chain dehydrogenases/reductases accounts for sex pheromone evolution in Nasonia.
Scientific Reports 6 (34697), S. 1-13.
Busch, Florian,
Rajendran, Chitra,
Heyn, Kristina,
Schlee, Sandra,
Merkl, Rainer und
Sterner, Reinhard
(2016)
Ancestral Tryptophan Synthase Reveals Functional Sophistication of Primordial Enzyme Complexes.
Cell Chemical Biology 23 (6), S. 709-715.
Volltext nicht vorhanden.
Ece, Selin,
Evran, Serap ,
Janda, Jan-Oliver,
Merkl, Rainer und
Sterner, Reinhard
(2015)
Improving thermal and detergent stability of Bacillus stearothermophilus neopullulanase by rational enzyme design.
Protein Engineering, Design and Selection 28 (6), S. 147-151.
Volltext nicht vorhanden.
Sommer, Bettina,
Waege, Ingrid,
Pöllmann, David,
Seitz, Tobias,
Thomm, Michael,
Sterner, Reinhard und
Hausner, Winfried
(2014)
Activation of a chimeric Rpb5/RpoH subunit using library selection.
Plos One 9.
Reisinger, Bernd,
Sperl, Josef,
Holinski, Alexandra ,
Schmid, Veronika,
Rajendran, Chitra,
Carstensen, Linn,
Schlee, Sandra,
Blanquart, Samuel,
Merkl, Rainer und
Sterner, Reinhard
(2014)
Evidence for the Existence of Elaborate Enzyme Complexes in the Paleoarchean Era.
Journal of the American Chemical Society 136 (1), S. 122-129.
Volltext nicht vorhanden.
Reisinger, Bernd,
Kuzmanovic, Natascha,
Löffler, Patrick,
Merkl, Rainer ,
König, Burkhard und
Sterner, Reinhard
(2014)
Exploiting Protein Symmetry To Design Light-Controllable Enzyme Inhibitors.
Angewandte Chemie International Edition 53, S. 595-598.
Volltext nicht vorhanden.
Busch, Florian,
Rajendran, Chitra,
Mayans, Olga ,
Löffler, Patrick,
Merkl, Rainer und
Sterner, Reinhard
(2014)
TrpB2 Enzymes are O-Phospho-l-serine Dependent Tryptophan Synthases.
Biochemistry 53 (38), S. 6078-6083.
Volltext nicht vorhanden.
Schlee, Sandra,
Dietrich, Susanne,
Kurćon, Tomasz,
Delaney, Pamela,
Goodey, Nina M. und
Sterner, Reinhard
(2013)
Kinetic Mechanism of Indole-3-glycerol Phosphate Synthase.
Biochemistry 52 (1), S. 132-142.
Volltext nicht vorhanden.
Meier, Monika M.,
Rajendran, Chitra,
Malisi, Christoph,
Fox, Nicholas G.,
Xu, Chengfu,
Schlee, Sandra,
Barondeau, David P. ,
Höcker, Birte,
Sterner, Reinhard und
Raushel, Frank M.
(2013)
Molecular Engineering of Organophosphate Hydrolysis Activity from a Weak Promiscuous Lactonase Template.
Journal of the American Chemical Society 135 (31), S. 11670-11677.
Volltext nicht vorhanden.
Dietrich, Susanne,
Borst, Nadine,
Schlee, Sandra,
Schneider, Daniel,
Janda, Jan-Oliver,
Sterner, Reinhard und
Merkl, Rainer
(2012)
Experimental assessment of the importance of amino acid positions identified by an entropy-based correlation analysis of multiple sequence alignments.
Biochemistry.
Volltext nicht vorhanden.
Reisinger, B.,
Bocola, M.,
List, F.,
Claren, J.,
Rajendran, C. und
Sterner, R.
(2012)
A sugar isomerization reaction established on various ( )8-barrel scaffolds is based on substrate-assisted catalysis.
Protein Engineering Design and Selection 25 (11), S. 751-760.
Volltext nicht vorhanden.
List, Felix,
Vega, M. Cristina ,
Razeto, Adelia,
Häger, Michaela C.,
Sterner, Reinhard und
Wilmanns, Matthias
(2012)
Catalysis Uncoupling in a Glutamine Amidotransferase Bienzyme by Unblocking the Glutaminase Active Site.
Chemistry & Biology 19 (12), S. 1589-1599.
Volltext nicht vorhanden.
Carstensen, Linn,
Sperl, Josef M.,
Bocola, Marco,
List, Felix,
Schmid, Franz X. und
Sterner, Reinhard
(2012)
Conservation of the Folding Mechanism between Designed Primordial (βα)8-Barrel Proteins and Their Modern Descendant.
Journal of the American Chemical Society 134 (30), S. 12786-12791.
Volltext nicht vorhanden.
Peterhoff, David,
Zellner, Hermann,
Guldan, Harald,
Merkl, Rainer ,
Sterner, Reinhard und
Babinger, Patrick
(2012)
Dimerization determines substrate specificity of a bacterial prenyltransferase.
Chembiochem : a European journal of chemical biology 13 (9), S. 1297-1303.
Volltext nicht vorhanden.
Fischer, André,
Seitz, Tobias,
Lochner, Adriane,
Sterner, Reinhard,
Merkl, Rainer und
Bocola, Marco
(2011)
A Fast and Precise Approach for Computational Saturation Mutagenesis and its Experimental Validation by Using an Artificial (βα)8-Barrel Protein.
ChemBioChem.
Volltext nicht vorhanden.
Richter, Markus,
Bosnali, Manal,
Carstensen, Linn,
Seitz, Tobias,
Durchschlag, Helmut,
Blanquart, Samuel,
Merkl, Rainer und
Sterner, Reinhard
(2010)
Computational and Experimental Evidence for the Evolution of a (βα)8-Barrel Protein from an Ancestral Quarter-Barrel Stabilised by Disulfide Bonds.
Journal of Molecular Biology 398 (5), S. 763-773.
Volltext nicht vorhanden.
Seitz, Tobias,
Thoma, Ralf,
Schoch, Guillaume A.,
Stihle, Martine,
Benz, Jörg,
D'Arcy, Brigitte,
Wiget, Andrea,
Ruf, Armin,
Hennig, Michael und
Sterner, Reinhard
(2010)
Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening.
Journal of molecular biology 403 (4), S. 562-577.
Volltext nicht vorhanden.
Drzewiecki, Katharina,
Angelov, Angel ,
Ballschmiter, Meike,
Tiefenbach, Klaus-Jürgen,
Sterner, Reinhard und
Liebl, Wolfgang
(2010)
Hyperthermostable acetyl xylan esterase.
Microbial biotechnology 3 (1), S. 84-92.
Volltext nicht vorhanden.
Ehrmann, Alexander,
Richter, Klaus ,
Busch, Florian,
Reimann, Julia,
Albers, Sonja-Verena und
Sterner, Reinhard
(2010)
Ligand-induced formation of a transient tryptophan synthase complex with aßß subunit stoichiometry.
Biochemistry (49), S. 10842-10853.
Volltext nicht vorhanden.
Schlee, Sandra,
Deuss, Miriam,
Bruning, Marc,
Ivens, Andreas,
Schwab, Thomas,
Hellmann, Nadja,
Mayans, Olga und
Sterner, Reinhard
(2009)
Activation of anthranilate phosphoribosyltransferase from Sulfolobus solfataricus by removal of magnesium inhibition and acceleration of product release.
Biochemistry 48 (23), S. 5199-209.
Volltext nicht vorhanden.
Xiang, Dao Feng,
Kolb, Peter ,
Fedorov, Alexander A.,
Meier, Monika M.,
Fedorov, Lena V.,
Nguyen, T. Tinh,
Sterner, Reinhard ,
Almo, Steven C.,
Shoichet, Brian K. und
Raushel, Frank M.
(2009)
Functional annotation and three-dimensional structure of Dr0930 from Deinococcus radiodurans, a close relative of phosphotriesterase in the amidohydrolase superfamily.
Biochemistry 48 (10), S. 2237-47.
Volltext nicht vorhanden.
Fischer, André,
Enkler, Nils,
Neudert, Gerd,
Bocola, Marco,
Sterner, Reinhard und
Merkl, Rainer
(2009)
TransCent: computational enzyme design by transferring active sites and considering constraints relevant for catalysis.
BMC Bioinformatics 10, S. 54.
Reetz, Manfred T.,
Rentzsch, Martin,
Pletsch, Andreas,
Taglieber, Andreas,
Hollmann, Frank ,
Mondière, Régis J. G.,
Dickmann, Norbert,
Höcker, Birte,
Cerrone, Simona,
Haeger, Michaela C. und
Sterner, Reinhard
(2008)
A robust protein host for anchoring chelating ligands and organocatalysts.
Chembiochem : a European journal of chemical biology 9 (4), S. 552-64.
Volltext nicht vorhanden.
Sterner, Reinhard,
Merkl, Rainer und
Raushel, Frank M.
(2008)
Computational design of enzymes.
Chemistry & Biology 15 (5), S. 421-423.
Volltext nicht vorhanden.
Marino, Marco,
Deuss, Miriam,
Svergun, Dmitri I. ,
Konarev, Petr V.,
Sterner, Reinhard und
Mayans, Olga
(2006)
Structural and Mutational Analysis of Substrate Complexation by Anthranilate Phosphoribosyltransferase from Sulfolobus solfataricus.
The Journal of Biological Chemistry 281 (30), S. 21410-21421.
Zugang zum Volltext eingeschränkt.
Vega, M. Cristina,
Zou, Peijian,
Fernandez, Francisco J.,
Murphy, Gavin E.,
Sterner, Reinhard,
Popov, Alexander und
Wilmanns, Matthias
(2005)
Regulation of the hetero-octameric ATP phosphoribosyl transferase complex from Thermotoga maritima by a tRNA synthetase-like subunit.
Molecular microbiology 55 (3), S. 675-86.
Volltext nicht vorhanden.
Schneider, Birgit,
Knöchel, Thorsten,
Darimont, Beatrice,
Hennig, Michael,
Dietrich, Susanne,
Babinger, Karin,
Kirschner, Kasper und
Sterner, Reinhard
(2005)
Role of the N-terminal extension of the (betaalpha)8-barrel enzyme indole-3-glycerol phosphate synthase for its fold, stability, and catalytic activity.
Biochemistry 44 (50), S. 16405-12.
Volltext nicht vorhanden.
Douangamath, Alice,
Walker, Martina,
Beismann-Driemeyer, Silke,
Vega-Fernandez, M. Cristina,
Sterner, Reinhard und
Wilmanns, Matthias
(2002)
Structural evidence for ammonia tunneling across the (beta alpha)(8) barrel of the imidazole glycerol phosphate synthase bienzyme complex.
Structure (London, England : 1993) 10 (2), S. 185-93.
Volltext nicht vorhanden.
Henn-Sax, Martina,
Thoma, Ralf,
Schmidt, Steffen,
Hennig, Michael,
Kirschner, Kasper und
Sterner, Reinhard
(2002)
Two (betaalpha)(8)-barrel enzymes of histidine and tryptophan biosynthesis have similar reaction mechanisms and common strategies for protecting their labile substrates.
Biochemistry 41 (40), S. 12032-42.
Volltext nicht vorhanden.
Jürgens, Catharina,
Strom, A.,
Wegener, D.,
Hettwer, Stefan,
Wilmanns, Matthias und
Sterner, Reinhard
(2000)
Directed evolution of a (beta alpha)8-barrel enzyme to catalyze related reactions in two different metabolic pathways.
Proceedings of the National Academy of Sciences of the United States of America 97 (18), S. 9925-30.
Volltext nicht vorhanden.
Lang, Detlef,
Thoma, Ralf,
Henn-Sax, Martina,
Sterner, Reinhard und
Wilmanns, Matthias
(2000)
Structural evidence for evolution of the beta/alpha barrel scaffold by gene duplication and fusion.
Science (New York, N.Y.) 289 (5484), S. 1546-50.
Volltext nicht vorhanden.
Thoma, Ralf,
Obmolova, G.,
Lang, D. A.,
Schwander, M.,
Jenö, P.,
Sterner, Reinhard und
Wilmanns, Matthias
(1999)
Efficient expression, purification and crystallisation of two hyperthermostable enzymes of histidine biosynthesis.
FEBS letters 454 (1-2), S. 1-6.
Volltext nicht vorhanden.
Sticht, H.,
Wildegger, G.,
Bentrop, D.,
Darimont, Beatrice,
Sterner, Reinhard und
Rösch, P.
(1996)
An NMR-derived model for the solution structure of oxidized Thermotoga maritima 1[Fe4-S4] ferredoxin.
European journal of biochemistry / FEBS 237 (3), S. 726-35.
Volltext nicht vorhanden.
Sterner, Reinhard,
Kleemann, G. R.,
Szadkowski, H.,
Lustig, A.,
Hennig, Michael und
Kirschner, Kasper
(1996)
Phosphoribosyl anthranilate isomerase from Thermotoga maritima is an extremely stable and active homodimer.
Protein science : a publication of the Protein Society 5 (10), S. 2000-8.
Volltext nicht vorhanden.
Sterner, Reinhard,
Dahm, A.,
Darimont, Beatrice,
Ivens, Andreas,
Liebl, W. und
Kirschner, Kasper
(1995)
(Beta alpha)8-barrel proteins of tryptophan biosynthesis in the hyperthermophile Thermotoga maritima.
The EMBO journal 14 (18), S. 4395-402.
Volltext nicht vorhanden.
Wildegger, G.,
Bentrop, D.,
Ejchart, A.,
Alber, M.,
Hage, A.,
Sterner, Reinhard und
Rösch, P.
(1995)
1H nuclear-magnetic-resonance investigation of oxidized Fe4S4 ferredoxin from Thermotoga maritima. Hyperfine-shifted resonances, sequence-specific assignments and secondary structure.
European journal of biochemistry / FEBS 229 (3), S. 658-68.
Volltext nicht vorhanden.
Hennig, Michael,
Darimont, Beatrice,
Sterner, Reinhard,
Kirschner, Kasper und
Jansonius, J. N.
(1995)
2.0 A structure of indole-3-glycerol phosphate synthase from the hyperthermophile Sulfolobus solfataricus: possible determinants of protein stability.
Structure (London, England : 1993) 3 (12), S. 1295-306.
Volltext nicht vorhanden.
Sterner, Reinhard,
Vogl, T.,
Hinz, H. J.,
Penz, F.,
Hoff, R.,
Föll, R. und
Decker, H.
(1995)
Extreme thermostability of tarantula hemocyanin.
FEBS letters 364 (1), S. 9-12.
Volltext nicht vorhanden.
Diese Liste wurde erzeugt am Fri Dec 20 06:37:27 2024 CET.