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Number of items: 145.

2026

Wang, Meng, Buthut, Maria, Meinhardt, Jenny, Otto, Carolin, Gallaccio, Gerardina, Fernández-Zapata, Camila, Teves, Matteo, Samol, Claudia, Dettmer, Katja , Heckscher, Simon, Kamboj, Sakshi, Bahar, Yozlem, Conrad, Christian, Böttcher, Christian, Kunkel, Desiree, Ruprecht, Klemens, Paul, Friedemann, Oefner, Peter J. , Radbruch, Helena, Gronwald, Wolfram, Prüß, Harald and Böttcher, Chotima (2026) Immune-proteo-metabolomic changes link to Aβ and tau pathology in Alzheimer disease. Alzheimer's & dementia : the journal of the Alzheimer's Association 22 (4), e71359.

Linz, Charlotte, Tsenova, Kristiyana, Dettmer, Katja , Ellmann, Lisa, Oefner, Peter J. , Gronwald, Wolfram, Farowski, Fedja, Rüb, Alina M., Freedberg, Daniel E., Koehler, Philipp, Borrega, Jorge Garcia, Naendrup, Jan-Hendrik, Vehreschild, Maria J. G. T. and Böll, Boris (2026) Integrating intestinal microbiome and urinary metabolome data to predict secondary infection in critically ill patients. Critical Care. (In Press)

Reindl, Alexander, Samol, Claudia, Haerteis, Silke , Zacharias, Helena U., Dettmer, Katja , Oefner, Peter J. and Gronwald, Wolfram (2026) Simultaneous determination of free and total metabolite concentrations in proteinaceous specimens by 1D 1H CPMG NMR. Cell Reports Methods 6 (1), p. 101291.

2025

Babl, Nathalie , Voll, Florian, Martowicz, Agnieszka, Bruss, Christina, Maddaloni, Marianna, Schmidl, Christian , Rehli, Michael , Loipfinger, Stefan, Strieder, Nicholas , Gebhard, Claudia , Hoffmann, Petra, Singh, Sukh M., Sala-Hojman, Ada, Ferretti, Roberta, Matos, Carina , Simon, Malte , Brummer, Christina, Schnell, Annette , Hofbauer, Joshua, Decking, Sonja-Maria, Hau, Peter , Vollmann-Zwerenz, Arabel, Dettmer, Katja , Oefner, Peter J. , Althammer, Michael, Laufs, Johanna, Friedl, Sarah, Heinrich, Timo, Herhaus, Christian, Evert, Katja , Mayr, Roman , Afonso, Julieta, Baltazar, Fatima, Herr, Wolfgang, Siska, Peter J. , Renner, Kathrin and Kreutz, Marina (2025) Lactic acid promotes an MDSC-like phenotype via HIF1α stabilization with impact on prognosis in renal cell carcinoma. Cancer Letters 639, p. 218209.

Anders, Wibke, Yarritu, Alex, Thiele, Arne, Szijarto, Istvan Andras, Rauch, Ariana, McParland, Victoria, Kamboj, Sakshi, Dettmer, Katja , Gronwald, Wolfram, Oefner, Peter J. , Bartolomaeus, Hendrik and Wilck, Nicola (2025) #3531 The microbiome and its metabolites promote cardiac remodeling in chronic kidney disease via the AhR-IL17A Axis. Nephrology Dialysis Transplantation 40. Fulltext not available.

Simeth, Jakob , Engelmann, Simon, Mayr, Roman , Kaelble, Sebastian, Weber, Florian , Pichler, Renate, Dettmer, Katja , Oefner, Peter J. , Höring, Marcus , Symeou, Luisa, Freitag, Katharina, Wagner, Kilian, Burger, Maximilian, Herr, Wolfgang, Kreutz, Marina , Spang, Rainer , Liebisch, Gerhard and Siska, Peter J. (2025) Lipid metabolism of clear cell renal cell carcinoma predicts survival and affects intratumoral CD8 T cells. Translational Oncology 61, p. 102513.

Heckscher, Simon, Ihlo, Nicolas A., Schueler, Jan, Kellermeier, Fabian, Werner, Jens M. , Nuebel, Barbara, Gross, Verena, May, Matthias, Wullich, Bernd, Kammerl, Martin, Gnewuch, Carsten, Burkhardt, Ralph , Buchholz, Björn, Pion, Eric, Aung, Thiha, Banas, Miriam, Schlitt, Hans J. , Oefner, Peter J. , Dettmer, Katja , Gronwald, Wolfram , Behr, Merle , Haerteis, Silke and Schmidt, Katharina M. (2025) Metabolomic profiling of renal cyst fluid in advanced ADPKD: insights from dialysis and transplantation cohorts. Metabolomics 21 (4).

Träger, Constantin, Kaiser, Maria, Freudenstein, David, Heckscher, Simon, Dettmer, Katja , Oefner, Peter J. , Liebisch, Gerhard , Hiergeist, Andreas , Gessner, André , Lee, De-Hyung, Angstwurm, Klemens , Linker, Ralf A. and Haase, Stefanie (2025) A probiotic approach identifies a Treg-centred immunoregulation via modulation of gut microbiota metabolites in people with multiple sclerosis and healthy individuals. eBioMedicine 116, p. 105743.

2024

Schwab, Annemarie, Siddiqui, Mohammad Aarif, Ramesh, Vignesh, Gollavilli, Paradesi Naidu, Turtos, Adriana Martinez, Møller, Sarah Søgaard, Pinna, Luisa, Havelund, Jesper F, Rømer, Anne Mette A, Ersan, Pelin Gülizar, Parma, Beatrice, Marschall, Sabine, Dettmer, Katja , Alhusayan, Mohammed, Bertoglio, Pietro, Querzoli, Giulia, Mielenz, Dirk, Sahin, Ozgur, Færgeman, Nils J, Asangani, Irfan A and Ceppi, Paolo (2024) Polyol pathway-generated fructose is indispensable for growth and survival of non-small cell lung cancer. Cell death & differentiation 32, pp. 587-597.

Siddique, Md Nur A Alam, Kellermeier, Fabian, Ölke, Martha, Zhao, Mingming, Büssow, Konrad, Oefner, Peter J., Lührmann, Anja, Dettmer, Katja and Lang, Roland (2024) Divergent effects of itaconate isomers on Coxiella burnetii growth in macrophages and in axenic culture. Frontiers in Immunology 15.

Siddique, Md Nur A Alam, Kellermeier, Fabian, Ölke, Martha, Zhao, Mingming, Büssow, Konrad, Oefner, Peter J., Lührmann, Anja, Dettmer, Katja and Lang, Roland (2024) Divergent effects of itaconate isomers on Coxiella burnetii growth in macrophages and in axenic culture. Frontiers in Immunology 15, p. 1427457.

Wrage, Marius, Holland, Tim, Nüse, Björn, Kaltwasser, Johanna, Fröhlich, Jessica, Arnold, Harald, Gießler, Claudia, Flamann, Cindy, Bruns, Heiko, Berges, Johannes, Daniel, Christoph, Hoffmann, Markus H., Anish, Chakkumkal, Seeberger, Peter H., Bogdan, Christian, Dettmer, Katja , Rauh, Manfred and Mattner, Jochen (2024) Cell type-specific modulation of metabolic, immune-regulatory, and anti-microbial pathways by CD101. Mucosal immunology 17 (5), pp. 892-910.

Hammon, Kathrin, Renner, Kathrin, Althammer, Michael, Voll, Florian, Babl, Nathalie, Decking, Sonja-Maria, Siska, Peter J. , Matos, Carina, Conejo, Zugey Elizabeth Cárdenas, Mendes, Karina , Einwag, Friederike, Siegmund, Heiko, Iberl, Sabine, Berger, Raffaela S. , Dettmer, Katja, Schoenmehl, Rebecca, Brochhausen, Christoph , Herr, Wolfgang, Oefner, Peter J. , Rehli, Michael , Thomas, Simone and Kreutz, Marina (2024) D-2-hydroxyglutarate supports a tolerogenic phenotype with lowered major histocompatibility class II expression in non-malignant dendritic cells and acute myeloid leukemia cells. Haematologica.

2023

Babl, Nathalie, Decking, Sonja-Maria, Voll, Florian, Althammer, Michael, Sala-Hojman, Ada, Ferretti, Roberta, Korf, Clarissa, Schmidl, Christian, Schmidleithner, Lisa, Nerb, Benedikt, Matos, Carina , Koehl, Gudrun E., Siska, Peter J. , Bruss, Christina, Kellermeier, Fabian, Dettmer, Katja , Oefner, Peter J. , Wichland, Marvin, Ugele, Ines, Bohr, Christopher, Herr, Wolfgang, Ramaswamy, Shivapriya, Heinrich, Timo, Herhaus, Christian, Kreutz, Marina and Renner, Kathrin (2023) MCT4 blockade increases the efficacy of immune checkpoint blockade. Journal for ImmunoTherapy of Cancer 11 (10), e007349.

Buck, Lena, Schmidt, Tobias, Feist, Maren, Schwarzfischer, Philipp, Kube, Dieter, Oefner, Peter J. , Zacharias, Helena U., Altenbuchinger, Michael , Dettmer, Katja , Gronwald, Wolfram and Spang, Rainer (2023) Anomaly detection in mixed high dimensional molecular data. Bioinformatics 39 (8), btad501.

Fadil, Fadi , Samol, Claudia, Berger, Raffaela S. , Kellermeier, Fabian, Gronwald, Wolfram , Oefner, Peter J. and Dettmer, Katja (2023) Data archive of "Isotope Ratio Outlier Analysis (IROA) for HPLC–TOFMS-Based Metabolomics of Human Urine". [Dataset]

Nanadikar, Maithily S., Vergel Leon, Ana M., Guo, Jia, van Belle, Gijsbert J., Jatho, Aline, Philip, Elvina S., Brandner, Astrid F., Böckmann, Rainer A., Shi, Runzhu, Zieseniss, Anke, Siemssen, Carla M., Dettmer, Katja , Brodesser, Susanne, Schmidtendorf, Marlen, Lee, Jingyun, Wu, Hanzhi, Furdui, Cristina M., Brandenburg, Sören, Burgoyne, Joseph R., Bogeski, Ivan, Riemer, Jan, Chowdhury, Arpita, Rehling, Peter, Bruegmann, Tobias, Belousov, Vsevolod V. and Katschinski, Dörthe M. (2023) IDH3γ functions as a redox switch regulating mitochondrial energy metabolism and contractility in the heart. Nature Communications 14 (1). Fulltext not available.

Seliger, Corinna, Rauer, Lisa , Wüster, Anne-Louise, Moeckel, Sylvia, Leidgens, Verena, Jachnik, Birgit, Ammer, Laura-Marie, Heckscher, Simon, Dettmer, Katja, Riemenschneider, Markus J., Oefner, Peter J., Proescholdt, Martin A., Vollmann-Zwerenz, Arabel and Hau, Peter (2023) Heterogeneity of Amino Acid Profiles of Proneural and Mesenchymal Brain-Tumor Initiating Cells. International journal of molecular sciences 24 (4).

Mauermeir, Michael, Ölke, Martha, Hayek, Inaya, Schulze-Luehrmann, Jan, Dettmer, Katja , Oefner, Peter J. , Berens, Christian, Menge, Christian and Lührmann, Anja (2023) Bovine blood derived macrophages are unable to control replication under hypoxic conditions. Frontiers in immunology 14, p. 960927.

Schoeppe, Robert, Babl, Nathalie, Decking, Sonja-Maria, Schönhammer, Gabriele, Siegmund, Andreas, Bruss, Christina, Dettmer, Katja , Oefner, Peter J. , Frick, Linus, Weigert, Anna, Jantsch, Jonathan, Herr, Wolfgang, Rehli, Michael , Renner, Kathrin and Kreutz, Marina (2023) Glutamine synthetase expression rescues human dendritic cell survival in a glutamine-deprived environment. Frontiers in Oncology 13, pp. 1-12.

Ugele, Ines, Wehrstein, Monika, Dettmer, Katja, Symeou, Luisa, Michaelides, Ioannis , Künzel, Julian , Oefner, Peter J., Kreutz, Marina, Bohr, Christopher and Renner, Kathrin (2023) Zusammenspiel von Tumormetabolismus und Immuninfiltrat im Kopf-Hals-Plattenepithelkarzinom. In: 94. Jahresversammlung Deutsche Gesellschaft für Hals-NasenOhren-Heilkunde, Kopf- und Hals-Chirugie e.V., Bonn, 17.-20. Mai 2023, Leipzig. Fulltext not available.

2022

Kohl, Lisa, Siddique, Md Nur A. Alam , Bodendorfer, Barbara, Berger, Raffaela, Preikschat, Annica, Daniel, Christoph, Ölke, Martha, Liebler‐Tenorio, Elisabeth, Schulze‐Luehrmann, Jan, Mauermeir, Michael, Yang, Kai‐Ting , Hayek, Inaya, Szperlinski, Manuela, Andrack, Jennifer, Schleicher, Ulrike, Bozec, Aline, Krönke, Gerhard, Murray, Peter J. , Wirtz, Stefan, Yamamoto, Masahiro, Schatz, Valentin, Jantsch, Jonathan, Oefner, Peter J., Degrandi, Daniel, Pfeffer, Klaus, Mertens‐Scholz, Katja, Rauber, Simon , Bogdan, Christian, Dettmer, Katja, Lührmann, Anja and Lang, Roland (2022) Macrophages inhibit Coxiella burnetii by the ACOD1 ‐itaconate pathway for containment of Q fever. EMBO Molecular Medicine, e15931.

Seliger, Corinna, Meyer, Anne-Louise, Leidgens, Verena, Rauer, Lisa, Moeckel, Sylvia, Jachnik, Birgitt, Proske, Judith, Dettmer, Katja, Rothhammer-Hampl, Tanja, Kaulen, Leon D., Riemenschneider, Markus J., Oefner, Peter J., Kreutz, Marina , Schmidt, Nils-Ole, Merrill, Marsha, Uhl, Martin, Renner, Kathrin, Vollmann-Zwerenz, Arabel, Proescholdt, Martin A. and Hau, Peter (2022) Metabolic Heterogeneity of Brain Tumor Cells of Proneural and Mesenchymal Origin. International Journal of Molecular Sciences 23 (19), p. 11629. Fulltext not available.

Fadil, Fadi , Samol, Claudia, Berger, Raffaela S. , Kellermeier, Fabian, Gronwald, Wolfram , Oefner, Peter J. and Dettmer, Katja (2022) Isotope Ratio Outlier Analysis (IROA) for HPLC–TOFMS-Based Metabolomics of Human Urine. Metabolites 12 (8), p. 741.

Decking, Sonja-Maria, Bruss, Christina, Babl, Nathalie, Bittner, Sebastian, Klobuch, Sebastian, Thomas, Simone , Feuerer, Markus, Hoffmann, Petra, Dettmer, Katja , Oefner, Peter J. , Renner, Kathrin and Kreutz, Marina (2022) LDHB Overexpression Can Partially Overcome T Cell Inhibition by Lactic Acid. International journal of molecular sciences 23 (11), p. 5970.

Frick, Linus, Hinterland, Linda, Renner, Kathrin , Vogl, Marion, Babl, Nathalie, Heckscher, Simon, Weigert, Anna, Weiß, Susanne, Gläsner, Joachim, Berger, Raffaela , Oefner, Peter J. , Dettmer, Katja , Kreutz, Marina , Schatz, Valentin and Jantsch, Jonathan (2022) Acidic Microenvironments Found in Cutaneous Leishmania Lesions Curtail NO-Dependent Antiparasitic Macrophage Activity. Frontiers in Immunology 13, p. 789366.

2021

Tauber, Philipp, Sinha, Frederick, Berger, Raffaela S., Gronwald, Wolfram, Dettmer, Katja , Kuhn, Michaela, Trum, Maximilian, Maier, Lars S., Wagner, Stefan and Schweda, Frank (2021) Empagliflozin Reduces Renal Hyperfiltration in Response to Uninephrectomy, but Is Not Nephroprotective in UNx/DOCA/Salt Mouse Models. Frontiers in Pharmacology 12, p. 761855.

Siska, Peter J. , Jiao, Jing, Matos, Carina, Singer, Katrin, Berger, Raffaela S. , Dettmer, Katja , Oefner, Peter J. , Cully, Michelle D., Wang, Zhonglin, Quinn III, William J., Oliff, Kristen N., Wilkins, Benjamin J., Christensen, Lanette M., Wang, Liqing, Hancock, Wayne W., Baur, Joseph A., Levine, Matthew H., Ugele, Ines, Mayr, Roman, Renner, Kathrin , Zhou, Liang, Kreutz, Marina and Beier, Ulf H. (2021) Kynurenine induces T cell fat catabolism and has limited suppressive effects in vivo. EBioMedicine 74, p. 103734.

Schöller, Eva, Marks, James, Marchand, Virginie , Bruckmann, Astrid, Powell, Christopher A., Reichold, Markus, Mutti, Christian Daniel , Dettmer, Katja , Feederle, Regina , Hüttelmaier, Stefan, Helm, Mark, Oefner, Peter J., Minczuk, Michal , Motorin, Yuri , Hafner, Markus and Meister, Gunter (2021) Balancing of mitochondrial translation through METTL8-mediated m3C modification of mitochondrial tRNAs. Molecular Cell 81 (23), 4810-4825.e12. Fulltext not available.

Arndt, Stephanie, Fadil, Fadi , Dettmer, Katja , Unger, Petra, Boskovic, Marko, Samol, Claudia, Bosserhoff, Anja-Katrin , Zimmermann, Julia, Gruber, Michael , Gronwald, Wolfram and Karrer, Sigrid (2021) Cold Atmospheric Plasma Changes the Amino Acid Composition in Solutions and Influences the Anti-Tumor Effect on Melanoma Cells. International Journal of Molecular Sciences 2021 (22), pp. 1-22.

Arndt, Stephanie, Fadil, Fadi , Dettmer, Katja , Unger, Petra, Boskovic, Marko, Samol, Claudia, Bosserhoff, Anja-Katrin , Zimmermann, Julia L., Gruber, Michael , Gronwald, Wolfram and Karrer, Sigrid (2021) Cold Atmospheric Plasma Changes the Amino Acid Composition of Solutions and Influences the Anti-Tumor Effect on Melanoma Cells. International Journal of Molecular Sciences 22 (15), p. 7886.

Meedt, Elisabeth, Hiergeist, Andreas , Gessner, André, Dettmer, Katja , Liebisch, Gerhard , Ghimire, Sakhila, Poeck, Hendrik, Edinger, Matthias, Wolff, Daniel , Herr, Wolfgang, Holler, Ernst and Weber, Daniela (2021) Prolonged suppression of butyrate producing bacteria is associated with acute gastrointestinal graft-versus-host disease and transplant related mortality after allogeneic stem cell transplantation. Clinical Infectious Diseases. Fulltext not available.

Petersen, Anders Ø., Jokinen, Martta, Plichta, Damian R., Liebisch, Gerhard , Gronwald, Wolfram, Dettmer, Katja , Oefner, Peter J., Vlamakis, Hera, Chung, Daniel C., Ranki, Annamari and Xavier, Ramnik J. (2021) Cytokine-specific autoantibodies shape the gut microbiome in autoimmune polyendocrine syndrome type 1. Journal of Allergy and Clinical Immunology, (In Press). Fulltext not available.

Kuo, Selena Z., Dettmer, Katja , Annavajhala, Medini K., Chong, David H., Uhlemann, Anne-Catrin, Abrams, Julian A., Oefner, Peter J. and Freedberg, Daniel E. (2021) Associations between urinary 3-indoxyl sulfate, a gut microbiome-derived biomarker, and patient outcomes after intensive care unit admission. Journal of Critical Care. Fulltext not available.

Oefner, Peter J. , Dettmer, Katja , Berger, Raffaela Sarah, Wachsmuth, Christian J., Waldhier, Magdalena C., Renner-Sattler, Kathrin, Thomas, Simone, Chaturvedi, Anuhar , Niller, Hans Helmut, Bumes, Elisabeth, Hau, Peter , Proescholdt, Martin A., Gronwald, Wolfram , Heuser, Michael and Kreutz, Marina (2021) Lactonization of the Oncometabolite D-2-Hydroxyglutarate Produces a Novel Endogenous Metabolite. Cancers 2021 (13), p. 1756.

Dowling, Jennifer K. , Afzal, Remsha , Gearing, Linden J., Cervantes-Silva, Mariana P., Annett, Stephanie, Davis, Gavin M., De Santi, Chiara, Assmann, Nadine, Dettmer, Katja , Gough, Daniel J. , Bantug, Glenn R., Hamid, Fidinny I., Nally, Frances K., Duffy, Conor P., Gorman, Aoife L., Liddicoat, Alex M., Lavelle, Ed C., Hess, Christoph, Oefner, Peter J., Finlay, David K., Davey, Gavin P., Robson, Tracy, Curtis, Annie M., Hertzog, Paul J., Williams, Bryan R. G. and McCoy, Claire E. (2021) Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages. Nature Communications 12, p. 1460.

2020

O'Brien, K. L., Assmann, Nadine, O'Connor, E., Keane, C., Walls, J., Choi, C., Oefner, Peter J., Gardiner, C. M., Dettmer, Katja and Finlay, D. K. (2020) De novo polyamine synthesis supports metabolic and functional responses in activated murine Natural Killer cells. Eur J Immunol, Accept.Art.. Fulltext not available.

Luger, Anna-Luisa , Lorenz, Nadja I., Urban, Hans, Divé, Iris, Engel, Anna L., Strassheimer, Florian, Dettmer, Katja, Zeiner, Pia S., Shaid, Shabnam, Struve, Nina, Kriegs, Malte, Hofmann, Ute , Oefner, Peter J., Harter, Patrick N., Steinbach, Joachim P. and Ronellenfitsch, Michael W. (2020) Activation of Epidermal Growth Factor Receptor Sensitizes Glioblastoma Cells to Hypoxia-Induced Cell Death. Cancers 12 (8), p. 2144.

Baier, Julia, Gänsbauer, Maximilian, Giessler, Claudia, Arnold, Harald, Muske, Mercedes, Schleicher, Ulrike, Lukassen, Sören , Ekici, Arif, Rauh, Manfred, Daniel, Christoph , Hartmann, Arndt, Schmid, Benjamin , Tripal, Philipp , Dettmer, Katja, Oefner, Peter J., Atreya, Raja, Wirtz, Stefan, Bogdan, Christian and Mattner, Jochen (2020) Arginase impedes the resolution of colitis by altering the microbiome and metabolome. Journal of Clinical Investigation 130 (11), pp. 5703-5720. Fulltext not available.

Sun, Xueni, Berger, Raffaela, Heinrich, Paul, Marchiq, Ibtissam, Pouyssegur, Jacques , Renner, Kathrin, Oefner, Peter J. and Dettmer, Katja (2020) Optimized Protocol for the In Situ Derivatization of Glutathione with N-Ethylmaleimide in Cultured Cells and the Simultaneous Determination of Glutathione/Glutathione Disulfide Ratio by HPLC-UV-QTOF-MS. Metabolites 10 (7), p. 292.

Akpa, C. A., Kleo, K., Oker, E., Tomaszewski, N., Messerschmidt, C. , López, C. , Wagener, R., Oehl-Huber, K., Dettmer, Katja, Schoeler, A., Lenze, D., Oefner, Peter J., Beule, D., Siebert, R., Capper, D., Dimitrova, L. and Hummel, M. (2020) Acquired resistance to DZNep-mediated apoptosis is associated with copy number gains of AHCY in a B-cell lymphoma model. BMC Cancer 20 (1), p. 427.

2019

Arlt, A., von Bonin, F., Rehberg, Thorsten, Perez-Rubio, Paula, Engelmann, Julia C. , Limm, Katharina , Reinke, S., Dullin, C., Sun, Xueni, Specht, R., Maulhardt, M., Linke, F. , Bunt, G., Klapper, W., Vockerodt, M., Wilting, J., Pukrop, T., Dettmer, Katja, Gronwald, Wolfram, Oefner, Peter J., Spang, Rainer and Kube, D. (2019) High CD206 levels in Hodgkin lymphoma-educated macrophages are linked to matrix-remodeling and lymphoma dissemination. Mol Oncol. Fulltext not available.

Sun, Xueni, Heinrich, Paul, Berger, Raffaela, Oefner, Peter J. and Dettmer, Katja (2019) Quantification and 13C-Tracer analysis of total reduced glutathione by HPLC-QTOFMS/MS. Anal. Chim. Acta 1080, pp. 127-137. Fulltext not available.

Rohweder, Bettina, Lehmann, Gerhard, Eichner, Norbert, Polen, T., Rajendran, Chitra, Ruperti, Fabian , Linde, Mona, Treiber, Thomas, Jung, Oona, Dettmer, Katja, Meister, Gunter, Bott, M. , Gronwald, Wolfram and Sterner, Reinhard (2019) Library Selection with a Randomized Repertoire of (βα)8-Barrel Enzymes Results in Unexpected Induction of Gene Expression. Biochemistry 58 (41), pp. 4207-4217. Fulltext not available.

Renner, Kathrin , Bruss, Christina, Schnell, Annette, Koehl, Gudrun, Becker, Holger M., Fante, Matthias, Menevse, Ayse-Nur, Kauer, Nathalie, Blazquez, Raquel, Hacker, Lisa, Decking, Sonja-Maria, Bohn, Toszka, Faerber, Stephanie, Evert, Katja, Aigle, Lisa, Amslinger, Sabine, Landa, Maria, Krijgsman, Oscar, Rozeman, Elisa A., Brummer, Christina, Siska, Peter J., Singer, Katrin, Pektor, Stefanie, Miederer, Matthias, Peter, Katrin, Gottfried, Eva, Herr, Wolfgang, Marchiq, Ibtisam, Pouyssegur, Jacques, Roush, William R., Ong, SuFey, Warren, Sarah, Pukrop, Tobias , Beckhove, Philipp , Lang, Sven A., Bopp, Tobias, Blank, Christian U., Cleveland, John L., Oefner, Peter J., Dettmer, Katja , Selby, Mark and Kreutz, Marina (2019) Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy. Cell Reports 29 (1), 135-150.e9.

Blazquez, R., Rietkoetter, E., Wenske, B., Wlochowitz, D., Sparrer, D., Vollmer, E., Muller, G., Seegerer, J., Sun, Xueni, Dettmer, Katja , Barrantes-Freer, A., Stange, L., Utpatel, K., Bleckmann, A., Treiber, H., Bohnenberger, H., Lenz, C., Schulz, M., Reimelt, C., Hackl, C., Grade, M., Buyuktas, D., Siam, L., Balkenhol, M., Stadelmann, C., Kube, D., Krahn, M. P., Proescholdt, M. A., Riemenschneider, M. J., Evert, M., Oefner, Peter J. , Klein, C. A., Hanisch, U. K., Binder, C. and Pukrop, Tobias (2019) LEF1 supports metastatic brain colonization by regulating glutathione metabolism and increasing ROS resistance in breast cancer. Int. J. Cancer. Fulltext not available.

Singer, Katrin, Dettmer, Katja , Unger, Petra, Schönhammer, Gabriele, Renner, Kathrin , Peter, Katrin , Siska, Peter J. , Berneburg, Mark , Herr, Wolfgang, Oefner, Peter J. , Karrer, Sigrid, Kreutz, Marina and Datz, Elisabeth (2019) Topical Diclofenac Reprograms Metabolism and Immune Cell Infiltration in Actinic Keratosis. Frontiers in Oncology 2019 (9), p. 605.

Singer, Katrin, Dettmer, Katja , Unger, Petra, Schoenhammer, Gabriele, Renner, Kathrin, Peter, Katrin, Siska, Peter J., Berneburg, Mark , Herr, Wolfgang, Oefner, Peter J. , Karrer, Sigrid, Kreutz, Marina and Datz, Elisabeth (2019) Topical Diclofenac Reprograms Metabolism and Immune Cell Infiltration in Actinic Keratosis. Front Oncol 9, p. 605.

Berger, Raffaela S. , Ellmann, Lisa, Reinders, Joerg, Kreutz, Marina, Stempfl, Thomas, Oefner, Peter J. and Dettmer, Katja (2019) Degradation of D-2-hydroxyglutarate in the presence of isocitrate dehydrogenase mutations. Scientific Reports 9 (1), pp. 1-11.

Hayek, I., Fischer, F., Schulze-Luehrmann, J., Dettmer, Katja , Sobotta, K., Schatz, V., Kohl, L., Boden, K., Lang, R., Oefner, Peter J. , Wirtz, S., Jantsch, Jonathan and Luhrmann, A. (2019) Limitation of TCA Cycle Intermediates Represents an Oxygen-Independent Nutritional Antibacterial Effector Mechanism of Macrophages. Cell Rep 26 (13), pp. 3502-3510.

Ugele, Ines, Cardenas-Conejo, Zugey Elizabeth, Hammon, Kathrin, Wehrstein, Monika, Bruss, Christina, Peter, Katrin, Singer, Katrin, Gottfried, Eva, Boesch, Jakob, Oefner, Peter J., Dettmer, Katja, Renner, Kathrin and Kreutz, Marina (2019) D-2-Hydroxyglutarate and L-2-Hydroxyglutarate Inhibit IL-12 Secretion by Human Monocyte-Derived Dendritic Cells. International Journal of Molecular Sciences 20 (3), p. 742.

Kieninger, Martn , Gruber, M., Knott, I., Dettmer, Katja, Oefner, Peter J., Bele, S., Wendl, C., Tuemmler, S., Graf, B. and Eissnert, C. (2019) Incidence of Arterial Hypotension in Patients Receiving Peroral or Continuous Intra-arterial Nimodipine After Aneurysmal or Perimesencephalic Subarachnoid Hemorrhage. Neurocrit Care. Fulltext not available.

Farowski, F., Solbach, P., Tsakmaklis, A., Brodesser, S., Cruz Aguilar, M. R., Cornely, O. A. , Dettmer, Katja, Higgins, P. G. , Suerbaum, S., Jazmati, N., Oefner, Peter J. and Vehreschild, M. J. G. T. (2019) Potential biomarkers to predict outcome of faecal microbiota transfer for recurrent Clostridioides difficile infection. Digestive and Liver Disease. Fulltext not available.

Naskali, E., Dettmer, Katja, Oefner, Peter J., Pereira, P. A. B. , Krohn, K., Auvinen, P. , Ranki, A. and Kluger, N. (2019) Serotonin and tryptophan metabolites, autoantibodies and gut microbiome in APECED. Endocrine Connections 8 (1), pp. 69-77.

2018

Heinrich, Paul, Kohler, Christian , Ellmann, Lisa, Kuerner, Paul, Spang, Rainer, Oefner, Peter J. and Dettmer, Katja (2018) Correcting for natural isotope abundance and tracer impurity in MS-, MS/MS- and high-resolution-multiple-tracer-data from stable isotope labeling experiments with IsoCorrectoR. Scientific Reports 8 (17910), pp. 1-10.

Zdralevic, M. , Brand, A., Di Ianni, L., Dettmer, Katja, Reinders, Jörg, Singer, K., Peter, K., Schnell, A., Bruss, C., Decking, S. M., Koehl, G., Felipe-Abrio, B., Durivault, J., Bayer, P., Evangelista, M., O'Brien, T., Oefner, Peter J., Renner, K., Pouyssegur, J. and Kreutz, Marina (2018) Double genetic disruption of lactate dehydrogenases A and B is required to ablate the. J. Biol. Chem. 293 (41), pp. 15947-15961. Fulltext not available.

Gerthofer, V., Kreutz, Marina, Renner, Kathrin, Jachnik, Birgit, Dettmer, Katja, Oefner, Peter J., Riemenschneider, Markus J., Proescholdt, Martin A., Vollmann-Zwerenz, Arabel, Hau, Peter and Seliger, Corinna (2018) Combined Modulation of Tumor Metabolism by Metformin and Diclofenac in Glioma. Int J Mol Sci 19 (9).

Weber, Daniela, Hiergeist, Andreas , Weber, Markus, Dettmer, Katja, Wolff, Daniel, Hahn, Joachim, Herr, Wolfgang, Gessner, Andre and Holler, Ernst (2018) Detrimental effect of broad-spectrum antibiotics on intestinal microbiome diversity in patients after allogeneic stem cell transplantation: Lack of commensal sparing antibiotics. Clin. Infect. Dis..

Reichold, M., Klootwijk, E. D., Reinders, Jörg , Otto, E. A., Milani, M., Broeker, C., Laing, C., Wiesner, J., Devi, S., Zhou, W., Schmitt, R., Tegtmeier, I., Sterner, C., Doellerer, H., Renner, K., Oefner, Peter J. , Dettmer, Katja , Simbuerger, J., Witzgall, R., Stanescu, H. C., Dumitriu, S., Iancu, D., Patel, V., Mozere, M., Tekman, M., Jaureguiberry, G., Issler, N., Kesselheim, A., Walsh, S. B., Gale, D. P., Howie, A. J., Martins, J. R., Hall, A. M., Kasgharian, M., O'Brien, K., Ferreira, C. R., Atwal, P. S., Jain, M., Hammers, A., Charles-Edwards, G., Choe, C. U., Isbrandt, D., Cebrian-Serrano, A., Davies, B., Sandford, R. N., Pugh, C., Konecki, D. S., Povey, S., Bockenhauer, D., Lichter-Konecki, U., Gahl, W. A., Unwin, R. J., Warth, Richard and Kleta, R. (2018) Glycine Amidinotransferase (GATM), Renal Fanconi Syndrome, and Kidney Failure. J. Am. Soc. Nephrol. 29 (7), pp. 1849-1858. Fulltext not available.

Loftus, R. M. , Assmann, N., Kedia-Mehta, N., O'Brien, K. L., Garcia, A., Gillespie, C., Hukelmann, J. L. , Oefner, Peter J., Lamond, A. I., Gardiner, C. M. , Dettmer, Katja, Cantrell, D. A., Sinclair, L. V. and Finlay, D. K. (2018) Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice. Nat Commun 9 (1), p. 2341.

Feist, M., Schwarzfischer, Philipp, Heinrich, Paul, Sun, Xueni, Kemper, J., von Bonin, F., Perez-Rubio, Paula, Taruttis, Franziska, Rehberg, Thorsten, Dettmer, Katja, Gronwald, Wolfram, Reinders, Jörg, Engelmann, Julia C. , Dudek, J., Klapper, W., Trumper, L., Spang, Rainer, Oefner, Peter J. and Kube, D. (2018) Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression. Nat Commun 9 (1), p. 1514.

DeFilipp, Z., Peled, J. U., Li, S., Mahabamunuge, J., Dagher, Z., Slingerland, A. E., Del Rio, C., Valles, B., Kempner, M. E., Smith, M., Brown, J., Dey, B. R., El-Jawahri, A., McAfee, S. L., Spitzer, T. R., Ballen, K. K., Sung, A. D., Dalton, T. E., Messina, J. A., Dettmer, Katja, Liebisch, G., Oefner, Peter J., Taur, Y., Pamer, E. G., Holler, E., Mansour, M. K., van den Brink, M. R. M., Hohmann, E., Jenq, R. R. and Chen, Y. B. (2018) Third-party fecal microbiota transplantation following allo-HCT reconstitutes microbiome diversity. Blood Advances 2 (7), pp. 745-753.

Böttcher, Martin, Renner, Kathrin, Berger, Raffaela , Mentz, Kristin, Thomas, Simone , Cardenas-Conejo, Zugey Elizabeth, Dettmer, Katja, Oefner, Peter J., Mackensen, Andreas, Kreutz, Marina and Mougiakakos, Dimitrios (2018) D-2-hydroxyglutarate interferes with HIF-1α stability skewing T-cell metabolism towards oxidative phosphorylation and impairing Th17 polarization. OncoImmunology 7 (7), e1445454.

Reichold, Markus, Klootwijk, Enriko D., Reinders, Joerg, Otto, Edgar A., Milani, Mario , Broeker, Carsten, Laing, Chris, Wiesner, Julia, Devi, Sulochana, Zhou, Weibin, Schmitt, Roland, Tegtmeier, Ines, Sterner, Christina, Doellerer, Hannes, Renner, Kathrin, Oefner, Peter J., Dettmer, Katja, Simbuerger, Johann M., Witzgall, Ralph, Stanescu, Horia C., Dumitriu, Simona, Iancu, Daniela, Patel, Vaksha, Mozere, Monika, Tekman, Mehmet , Jaureguiberry, Graciana, Issler, Naomi, Kesselheim, Anne, Walsh, Stephen B., Gale, Daniel P. , Howie, Alexander J., Martins, Joana R. , Hall, Andrew M., Kasgharian, Michael, O’Brien, Kevin, Ferreira, Carlos R., Atwal, Paldeep S., Jain, Mahim, Hammers, Alexander , Charles-Edwards, Geoffrey, Choe, Chi-Un, Isbrandt, Dirk, Cebrian-Serrano, Alberto, Davies, Ben, Sandford, Richard N., Pugh, Christopher, Konecki, David S., Povey, Sue, Bockenhauer, Detlef, Lichter-Konecki, Uta, Gahl, William A., Unwin, Robert J., Warth, Richard and Kleta, Robert (2018) Glycine Amidinotransferase (GATM), Renal Fanconi Syndrome, and Kidney Failure. Journal of the American Society of Nephrology 29 (7), pp. 1849-1858. Fulltext not available.

2017

Sekula, P. , Dettmer, Katja , Vogl, Franziska C., Gronwald, Wolfram, Ellmann, Lisa, Mohney, R. P., Eckardt, K. U., Suhre, K. , Kastenmüller, Gabi , Oefner, Peter J. and Köttgen, A. (2017) From Discovery to Translation: Characterization of C-Mannosyltryptophan and Pseudouridine as Markers of Kidney Function. Scientific Reports 7 (1), p. 17400. Fulltext not available.

Assmann, N., O'Brien, K. L., Donnelly, R. P., Dyck, L., Zaiatz-Bittencourt, V., Loftus, R. M., Heinrich, Paul, Oefner, Peter J., Lynch, L., Gardiner, C. M., Dettmer, Katja and Finlay, D. K. (2017) Srebp-controlled glucose metabolism is essential for NK cell functional responses. Nat. Immunol. 18 (11), pp. 1197-1206. Fulltext not available.

Wallmeier, Jens, Samol, Claudia, Ellmann, Lisa, Zacharias, Helena, Vogl, Franziska C., Garcia, Muriel, Dettmer, Katja , Oefner, Peter J. and Gronwald, Wolfram (2017) Quantification of metabolites by NMR spectroscopy in the presence of protein. Journal of Proteome Research 1535-3893. Fulltext not available.

Maliniemi, P. , Laukkanen, K., Vakeva, L., Dettmer, Katja , Lipsanen, T., Jeskanen, L., Bessede, A., Oefner, Peter J., Kadin, M. E. and Ranki, A. (2017) Biological and clinical significance of tryptophan-catabolizing enzymes in cutaneous T-cell lymphomas. Oncoimmunology 6 (3), e1273310. Fulltext not available.

Schwarzfischer, Philipp, Reinders, Jörg, Dettmer, Katja , Kleo, K., Dimitrova, L., Hummel, M., Feist, M., Kube, D., Szczepanowski, M., Klapper, W., Taruttis, Franziska, Engelmann, Julia C. , Spang, Rainer, Gronwald, Wolfram and Oefner, Peter J. (2017) Comprehensive metaboproteomics of Burkitt's and diffuse large B-cell lymphoma cell lines and primary tumor tissues reveals distinct differences in pyruvate content and metabolism. Journal of Proteome Research 16, pp. 1105-1120. Fulltext not available.

Weber, Daniela, Jenq, Robert R., Peled, Jonathan U. , Taur, Ying, Hiergeist, Andreas , Koestler, Josef, Dettmer, Katja , Weber, Markus, Wolff, Daniel, Hahn, Joachim, Pamer, Eric G., Herr, Wolfgang, Gessner, André, Oefner, Peter J., van den Brink, Marcel R. M. and Holler, Ernst (2017) Microbiota Disruption Induced by Early Use of Broad-Spectrum Antibiotics Is an Independent Risk Factor of Outcome after Allogeneic Stem Cell Transplantation. Biology of Blood and Marrow Transplantation 23 (5), pp. 845-852. Fulltext not available.

2016

Brand, A., Singer, K., Koehl, G. E., Kolitzus, M., Schoenhammer, G., Thiel, A., Matos, C., Bruss, C., Klobuch, S., Peter, K., Kastenberger, M., Bogdan, C., Schleicher, U., Mackensen, Andreas, Ullrich, E. , Fichtner-Feigl, S., Kesselring, R., Mack, M., Ritter, U., Schmid, M., Blank, C., Dettmer, Katja , Oefner, Peter J., Hoffmann, P., Walenta, S., Geissler, E. K., Pouyssegur, J., Villunger, A., Steven, A. , Seliger, B., Schreml, S., Haferkamp, S., Kohl, E., Karrer, S., Berneburg, Mark, Herr, Wolfgang, Mueller-Klieser, W., Renner, K. and Kreutz, Marina (2016) LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells. Cell Metabolism (Cell Metab.) 24 (5), pp. 657-671. Fulltext not available.

Vogl, Franziska C., Mehrl, S., Heizinger, L., Schlecht, I., Zacharias, Helena, Ellmann, L., Nürnberger, N., Gronwald, Wolfram, Leitzmann, M. F., Rossert, J., Eckardt, K. U., Dettmer, Katja and Oefner, Peter J. (2016) Evaluation of dilution and normalization strategies to correct for urinary output in HPLC-HRTOFMS metabolomics. Analytical and Bioanalytical Chemistry (Anal Bioanal Chem). Fulltext not available.

Altenbuchinger, Michael, Rehberg, Thorsten, Zacharias, Helena, Stämmler, Frank, Dettmer, Katja , Weber, Daniela, Hiergeist, Andreas, Gessner, Andre, Holler, Ernst, Oefner, Peter J. and Spang, Rainer (2016) Reference point insensitive molecular data analysis. Bioinformatics.

Limm, K., Dettmer, Katja , Reinders, Jörg, Oefner, Peter J. and Bosserhoff, A. K. (2016) Characterization of the Methylthioadenosine Phosphorylase Polymorphism rs7023954 - Incidence and Effects on Enzymatic Function in Malignant Melanoma. PLoS ONE 11 (8), e0160348.

Seliger, Corinna, Meyer, A. L., Renner, K., Leidgens, V., Moeckel, S., Jachnik, B., Dettmer, Katja , Tischler, U., Gerthofer, V., Rauer, L., Uhl, M., Proescholdt, M., Bogdahn, U., Riemenschneider, M. J., Oefner, Peter J., Kreutz, M., Vollmann-Zwerenz, A. and Hau, Peter (2016) Metformin inhibits proliferation and migration of glioblastoma cells independently of TGF-β2. Cell Cycle 15 (13), pp. 1755-1766. Fulltext not available.

Assmann, Nadine, Dettmer, Katja , Simbürger, Johann, Broeker, Carsten, Nuernberger, Nadine, Renner, Kathrin, Courtneidge, H., Klootwijk, E. D., Duerkop, Axel , Hall, A., Kleta, R., Oefner, Peter J. , Reichold, Markus and Reinders, Jörg (2016) Renal Fanconi Syndrome Is Caused by a Mistargeting-Based Mitochondriopathy. Cell Reports (Cell Rep) 15 (7), pp. 1423-1429.

Simburger, J. M., Dettmer, Katja , Oefner, Peter J. and Reinders, Jörg (2016) Optimizing the SWATH-MS-workflow for label-free proteomics. J Proteomics. Fulltext not available.

Weber, Daniela, Oefner, Peter J., Dettmer, Katja , Hiergeist, Andreas, Koestler, Josef, Gessner, Andre, Weber, Markus, Stämmler, Frank, Hahn, Joachim, Wolff, Daniel, Herr, Wolfgang and Holler, Ernst (2016) Rifaximin preserves intestinal microbiota balance in patients undergoing allogeneic stem cell transplantation. Bone Marrow Transplant.. Fulltext not available.

Voelxen, N. F., Walenta, S., Proescholdt, Martin A., Dettmer, Katja , Pusch, S. and Mueller-Klieser, W. (2016) Quantitative Imaging of D-2-Hydroxyglutarate in Selected Histological Tissue Areas by a Novel Bioluminescence Technique. Frontiers in Oncology 6, p. 46.

Henrich, F., Singer, Katrin, Poller, K., Bernhardt, L., Strobl, C. , Ritter, Axel P., Gottfried, E., Peter, Katrin, Dettmer, Katja , Oefner, Peter J., Bosserhoff, Anja-Katrin and Kreutz, Marina (2016) Suppressive effects of tumor cell-derived 5′-deoxy-5′-methylthioadenosine on human T cells. OncoImmunology 5, e1184802. Fulltext not available.

2015

Sekula, Peggy , Goek, Oemer-Necmi, Quaye, Lydia, Barrios, Clara, Levey, Andrew S., Römisch-Margl, Werner, Menni, Cristina , Yet, Idil, Gieger, Christian, Inker, Lesley A., Adamski, Jerzy, Gronwald, Wolfram, Illig, Thomas, Dettmer, Katja , Krumsiek, Jan, Oefner, Peter J. , Valdes, Ana M. , Meisinger, Christa, Coresh, Josef, Spector, Tim D., Mohney, Robert P., Suhre, Karsten, Kastenmüller, Gabi and Köttgen, Anna (2015) A Metabolome-Wide Association Study of Kidney Function and Disease in the General Population. Journal of the American Society of Nephrology (JASN) 27 (4), pp. 1175-1188.

Leisz, Sandra, Schulz, Kristin, Erb, Susanne, Oefner, Peter J. , Dettmer, Katja , Mougiakakos, Dimitrios, Wang, Ena, Marincola, Francesco M., Stehle, Franziska and Seliger, Barbara (2015) Distinct von Hippel-Lindau gene and hypoxia-regulated alterations in gene and protein expression patterns of renal cell carcinoma and their effects on metabolism. Oncotarget 6 (13), pp. 11395-11406.

Wachsmuth, Christian J., Hahn, Thomas A., Oefner, Peter J. and Dettmer, Katja (2015) Enhanced metabolite profiling using a redesigned atmospheric pressure chemical ionization source for gas chromatography coupled to high-resolution time-of-flight mass spectrometry. Anal Bioanal Chem (Analytical and Bioanalytical Chemistry) 407 (22), pp. 6669-6680. Fulltext not available.

Jantsch, Jonathan, Schatz, Valentin, Dettmer, Katja , Dick, Christopher, Ehrenschwender, Martin , Hellerbrand, Claus and Oefner, Peter J. (2015) Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen. Cell Reports 2015 (13), pp. 2048-2055.

Weber, Daniela, Oefner, Peter J. , Hiergeist, Andreas, Koestler, Josef, Gessner, Andre, Weber, Markus, Hahn, Joachim, Wolff, Daniel, Stämmler, Frank, Spang, Rainer, Herr, Wolfgang, Dettmer, Katja and Holler, Ernst (2015) Low urinary indoxyl sulfate levels early after transplantation reflect a disrupted microbiome and are associated with poor outcome. Blood 126 (14), pp. 1723-1728.

2014

Jitschin, Regina, Braun, Martina, Büttner, Maike, Dettmer, Katja, Bricks, Juliane, Berger, Jana, Eckart, Michael J., Krause, Stefan W., Oefner, Peter, Le Blanc, Katarina, Mackensen, Andreas and Mougiakakos, Dimitrios (2014) CLL-cells induce IDOhi CD14+HLA-DRlo myeloid derived suppressor cells that inhibit T-cell responses and promote TRegs. Blood. Fulltext not available.

Klootwijk, Enriko D., Reichold, Markus, Helip-Wooley, Amanda, Tolaymat, Asad, Broeker, Carsten, Robinette, Steven, Reinders, Jörg, Peindl, Dominika Elisabeth, Renner, Kathrin, Eberhart, Karin, Aßmann, Nadine, Oefner, Peter J., Dettmer, Katja, Sterner, Christina, Schroeder, Josef, Zorger, Niels, Witzgall, Ralph, Reinhold, Stephan W., Stanescu, Horia C., Bockenhauer, Detlef, Jaureguiberry, Gracian, Courtneidge, Holly, Hall, Andrew M., Wijeyesekera, Anisha, Holmes, Elaine, Nicholson, Jeremy K., O'Brien, Kevin, Bernardini, Isa, Krasnewich, Donna M., Arcos-Burgos, Mauricio, Izumi, Yuichiro, Nonoguchi, Hiroshi, Jia, Yuzhi, Reddy, Janardan K., Ilya, Mohammad, Unwin, Robert J., Gahl, William A., Warth, Richard and Kleta, Robert (2014) Mistargeting of Peroxisomal EHHADH and Inherited Renal Fanconi's Syndrome. The New England Journal of Medicine 370, pp. 129-138. Fulltext not available.

Dettmer, Katja (2014) Assessment of ionic liquid stationary phases for the GC analysis of fatty acid methyl esters. Analytical and Bioanalytical Chemistry 406, pp. 4931-4939. Fulltext not available.

Wachsmuth, Christian J., Dettmer, Katja , Lang, S. A., Mycielska, M. E. and Oefner, Peter J. (2014) Continuous water infusion enhances atmospheric pressure chemical ionization of methyl chloroformate derivatives in gas chromatography coupled to time-of-flight mass spectrometry-based metabolomics. Anal. Chem. 86 (18), pp. 9186-9195. Fulltext not available.

Mycielska, Maria, Wachsmuth, Christian J., Dettmer, Katja, Wagner, Christine, Oefner, Peter J., Geissler, Edward K. and Lang, Sven A. (2014) Hsp90 Inhibition Affects Cell Metabolism by Disrupting Mitochondrial Protein Insertion. HSOA Journal of Cell Biology and Cell Metabolism 1, 002.

2013

Thomas, Anja, Klein, Matthias S. , Stevens, Axel Peter, Reinders, Yvonne, Hellerbrand, Claus, Dettmer, Katja , Gronwald, Wolfram, Oefner, Peter J. and Reinders, Jörg (2013) Changes in the hepatic mitochondrial and membrane proteome in mice fed a non-alcoholic steatohepatitis inducing diet. Journal of proteomics 80, pp. 107-122. Fulltext not available.

Klein, Matthias S. , Almstetter, Martin F., Nürnberger, Nadine, Sigl, Gregor, Gronwald, Wolfram, Wiedemann, Steffi, Dettmer, Katja and Oefner, Peter J. (2013) Correlations between milk and plasma levels of amino and carboxylic acids in dairy cows. Journal of Proteome Research 12 (11), pp. 5223-5232.

Dettmer, Katja , Vogl, Franziska C., Ritter, Axel P., Zhu, Wentao, Nürnberger, Nadine, Kreutz, Marina, Oefner, Peter J. , Gronwald, Wolfram and Gottfried, Eva (2013) Distinct metabolic differences between various human cancer and primary cells. ELECTROPHORESIS 34 (19), pp. 2836-2847. Fulltext not available.

Czech, Barbara, Dettmer, Katja , Valletta, Daniela, Saugspier, Michael Sebastian, Koch, Andreas, Stevens, Axel Peter, Thasler, Wolfgang E., Müller, Martina, Oefner, Peter J. , Bosserhoff, Anja-Katrin and Hellerbrand, Claus (2013) Expression and function of methylthioadenosine phosphorylase in chronic liver disease. PloS ONE 8 (12), e80703.

Riechers, A., Schmidt, J., Dettmer, Katja , Oefner, Peter J. , Jachimczak, P., Schneider, A. and Bosserhoff, Anja-Katrin (2013) Inducing anti-tumor cytokines and an immune response in melanoma by inhibition of MIA using the peptide AR71. Eur J Dermatol 23 (6), pp. 820-825. Fulltext not available.

Dettmer, Katja, Gronwald, Wolfram and Oefner, Peter J. (2013) Instrumentelle Bioanalytik zur Stoffwechselanalytik. Blick in die Wissenschaft. Fulltext not available.

Kreutz, Marina, Gottfried, Eva, Lang, Sven A., Renner, Kathrin, Bosserhoff, Anja-Katrin , Gronwald, Wolfram, Rehli, Michael , Einhell, Sabine, Gedig, Isabel, Singer, Katrin, Seilbeck, Anton, Mackensen, Andreas, Grauer, Oliver, Hau, Peter, Dettmer, Katja , Andreesen, Reinhard and Oefner, Peter (2013) New aspects of an old drug: Diclofenac targets MYC and glucose metabolism in tumor cells. PLoS ONE 8 (7), e66987.

2012

Almstetter, Martin F., Oefner, Peter J. and Dettmer, Katja (2012) Comprehensive two-dimensional gas chromatography in metabolomics. Analytical and bioanalytical chemistry 402 (6), pp. 1993-2013. Fulltext not available.

Dettmer, Katja, Stevens, Axel Peter, Fagerer, Stephan R., Kaspar, Hannelore and Oefner, Peter J. (2012) Amino acid analysis in physiological samples by GC-MS with propyl chloroformate derivatization and iTRAQ-LC-MS/MS. Methods in molecular biology 828, pp. 165-181. Fulltext not available.

Dettmer, Katja, Stevens, Axel Peter, Fagerer, Stephan R., Kaspar, Hannelore and Oefner, Peter J. (2012) Amino acid analysis in physiological samples by GC-MS with propyl chloroformate derivatization and iTRAQ-LC-MS/MS. Methods in molecular biology 828, pp. 165-181. Fulltext not available.

van der Goot, Annemieke, Zhu, Wentao, Vázquez-Manrique, Rafael , Seinstra, Renée I., Dettmer, Katja , Michels, Helen, Farina, Francesca, Krijnen, Jasper, Melki, Ronald, Buijsman, Rogier C., Ruiz Silva, Mariana, Thijssen, Karen L., Kema, Ido P., Neri, Christian , Oefner, Peter J. and Nollen, Ellen A. A. (2012) Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation. Proceedings of the National Academy of Sciences of the United States of America 109 (37), pp. 14912-7. Fulltext not available.

Thomas, Anja, Stevens, Axel Peter, Klein, Matthias S. , Hellerbrand, Claus, Dettmer, Katja , Gronwald, Wolfram, Oefner, Peter J. and Reinders, Jörg (2012) Early changes in the liver-soluble proteome from mice fed a nonalcoholic steatohepatitis inducing diet. Proteomics 12 (9), pp. 1437-1451. Fulltext not available.

Almstetter, Martin F., Oefner, Peter J. and Dettmer, Katja (2012) Metabolic fingerprinting using comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry. Methods in molecular biology 815, pp. 399-411. Fulltext not available.

2011

Almstetter, Martin F., Appel, Inka, Dettmer, Katja , Gruber, Michael and Oefner, Peter J. (2011) Comparison of two algorithmic data processing strategies for metabolic fingerprinting by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry. Journal of chromatography A 1218 (39), pp. 7031-7038. Fulltext not available.

Kirovski, Georgi, Stevens, Axel Peter, Czech, Barbara, Dettmer, Katja , Weiss, Thomas S. , Wild, Peter, Hartmann, Arndt, Bosserhoff, Anja-Katrin , Oefner, Peter J. and Hellerbrand, Claus (2011) Down-regulation of methylthioadenosine phosphorylase (MTAP) induces progression of hepatocellular carcinoma via accumulation of 5'-deoxy-5'-methylthioadenosine (MTA). The American journal of pathology 178 (3), pp. 1145-1152. Fulltext not available.

Waldhier, Magdalena Ch., Almstetter, Martin F., Nürnberger, Nadine, Gruber, Michael , Dettmer, Katja and Oefner, Peter J. (2011) Improved enantiomer resolution and quantification of free D-amino acids in serum and urine by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry. Journal of chromatography A 1218 (28), pp. 4537-4544. Fulltext not available.

Dettmer, Katja, Stevens, A., Gronwald, Wolfram, Hellerbrand, Claus and Oefner, Peter J. (2011) Mass spectrometry based metabolomics to study the development of Non-alcoholic steatohepatitis. Zeitschrift für Gastroenterologie 49. Fulltext not available.

Dettmer, Katja , Nürnberger, Nadine, Kaspar, Hannelore, Gruber, Michael , Almstetter, Martin F. and Oefner, Peter J. (2011) Metabolite extraction from adherently growing mammalian cells for metabolomics studies: optimization of harvesting and extraction protocols. Analytical and bioanalytical chemistry 399 (3), pp. 1127-1139. Fulltext not available.

Wachsmuth, Christian, Almstetter, Martin F., Waldhier, Magdalena Ch., Gruber, Michael , Nürnberger, Nadine, Oefner, Peter J. and Dettmer, Katja (2011) Performance evaluation of gas chromatography-atmospheric pressure chemical ionization-time-of-flight mass spectrometry for metabolic fingerprinting and profiling. Analytical chemistry 83 (19), pp. 7514-7322. Fulltext not available.

Zhu, Wentao, Stevens, Axel Peter, Dettmer, Katja , Gottfried, Eva, Hoves, Sabine , Kreutz, Marina, Holler, Ernst, Canelas, André B., Kema, Ido and Oefner, Peter J. (2011) Quantitative profiling of tryptophan metabolites in serum, urine, and cell culture supernatants by liquid chromatography-tandem mass spectrometry. Analytical and bioanalytical chemistry 401 (10), pp. 3249-3261. Fulltext not available.

2010

Stevens, Axel Peter, Dettmer, Katja, Kirovski, Georgi, Samejima, Keijiro, Hellerbrand, Claus, Bosserhoff, Anja-Katrin and Oefner, Peter J. (2010) Quantification of intermediates of the methionine and polyamine metabolism by liquid chromatography-tandem mass spectrometry in cultured tumor cells and liver biopsies. Journal of chromatography A 1217 (19), pp. 3282-3288. Fulltext not available.

Waldhier, Magdalena Ch., Dettmer, Katja , Gruber, Michael and Oefner, Peter J. (2010) Comparison of derivatization and chromatographic methods for GC-MS analysis of amino acid enantiomers in physiological samples. Journal of chromatography B 878 (15-16), pp. 1103-1112. Fulltext not available.

Dettmer, Katja , Almstetter, Martin F., Appel, Inka, Nürnberger, Nadine, Schlamberger, Gregor, Gronwald, Wolfram, Meyer, Heinrich H. D. and Oefner, Peter J. (2010) Comparison of serum versus plasma collection in gas chromatography--mass spectrometry-based metabolomics. Electrophoresis 31 (14), pp. 2365-2373. Fulltext not available.

Dietl, Katrin, Renner, Kathrin, Dettmer, Katja , Timischl, Birgit, Eberhart, Karin, Dorn, Christoph, Hellerbrand, Claus, Kastenberger, Michael, Kunz-Schughart, Leoni A., Oefner, Peter J. , Andreesen, Reinhard, Gottfried, Eva and Kreutz, Marina (2010) Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes. Journal of immunology 184 (3), pp. 1200-1209. Fulltext not available.

Klein, Matthias S. , Almstetter, Martin F., Schlamberger, G., Nürnberger, Nadine, Dettmer, Katja , Oefner, Peter J. , Meyer, H. H. D., Wiedemann, Steffi and Gronwald, Wolfram (2010) Nuclear magnetic resonance and mass spectrometry-based milk metabolomics in dairy cows during early and late lactation. Journal of dairy science 93 (4), pp. 1539-1550. Fulltext not available.

Amann, Thomas, Bataille, Frauke, Spruss, Thilo, Dettmer, Katja , Wild, Peter J., Liedtke, Christian , Mühlbauer, Marcus, Kiefer, Paul, Oefner, Peter J. , Trautwein, Christian, Bosserhoff, Anja-Katrin and Hellerbrand, Claus (2010) Reduced expression of fibroblast growth factor receptor 2IIIb in hepatocellular carcinoma induces a more aggressive growth. The American journal of pathology 176 (3), pp. 1433-1442. Fulltext not available.

2009

Kaspar, Hannelore, Dettmer, Katja, Gronwald, Wolfram and Oefner, Peter J. (2009) Advances in amino acid analysis. Analytical and bioanalytical chemistry 393 (2), pp. 445-452. Fulltext not available.

Waldhier, Magdalena Ch., Gruber, Michael , Dettmer, Katja and Oefner, Peter J. (2009) Capillary electrophoresis and column chromatography in biomedical chiral amino acid analysis. Analytical and bioanalytical chemistry 394 (3), pp. 695-706. Fulltext not available.

Stevens, Axel Peter, Spangler, Barbara, Wallner, Susanne, Kreutz, Marina, Dettmer, Katja , Oefner, Peter J. and Bosserhoff, Anja-Katrin (2009) Direct and tumor microenvironment mediated influences of 5'-deoxy-5'-(methylthio)adenosine on tumor progression of malignant melanoma. Journal of cellular biochemistry 106 (2), pp. 210-219. Fulltext not available.

Almstetter, Martin F., Appel, Inka, Gruber, Michael , Lottaz, Claudio, Timischl, Birgit, Spang, Rainer, Dettmer, Katja and Oefner, Peter J. (2009) Integrative normalization and comparative analysis for metabolic fingerprinting by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry. Analytical chemistry 81 (14), pp. 5731-5739. Fulltext not available.

Baumann, Fusun, Leukel, Petra, Doerfelt, Anett, Beier, Christoph P., Dettmer, Katja , Oefner, Peter J. , Kastenberger, Michael, Kreutz, Marina, Nickl-Jockschat, Thomas , Bogdahn, Ulrich, Bosserhoff, Anja-Katrin and Hau, Peter (2009) Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2. Neuro-oncology 11 (4), pp. 368-380. Fulltext not available.

Kaspar, Hannelore, Dettmer, Katja , Chan, Queenie , Daniels, Scott, Nimkar, Subodh, Daviglus, Martha L., Stamler, Jeremiah, Elliott, Paul and Oefner, Peter J. (2009) Urinary amino acid analysis: a comparison of iTRAQ-LC-MS/MS, GC-MS, and amino acid analyzer. Journal of chromatography B 877 (20-21), pp. 1838-1846. Fulltext not available.

2008

Timischl, Birgit, Dettmer, Katja and Oefner, Peter J. (2008) Hyphenated mass spectrometry in the analysis of the central carbon metabolism. Analytical and Bioanalytical Chemistry 391, pp. 895-898. Fulltext not available.

Kaspar, Hannelore, Dettmer, Katja , Gronwald, Wolfram and Oefner, Peter J. (2008) Automated GC-MS analysis of free amino acids in biological fluids. J. Chromatogr. B 870 (2), pp. 222-232. Fulltext not available.

Timischl, B., Dettmer, Katja , Kaspar, H., Thieme, M. and Oefner, Peter J. (2008) Development of a quantitative, validated capillary electrophoresis-time of flight-mass spectrometry method with integrated high-confidence analyte identification for metabolomics. Electrophoresis 29 (10), pp. 2203-2214. Fulltext not available.

Aronov, P. A., Hall, L. M., Dettmer, Katja , Stephensen, C. B. and Hammock, B. D. (2008) Metabolic profiling of major vitamin D metabolites using Diels-Alder derivatization and ultra-performance liquid chromatography-tandem mass spectrometry. Analytical and Bioanalytical Chemistry 391 (5), pp. 1917-1930. Fulltext not available.

Stevens, A. P., Dettmer, Katja , Wallner, S., Bosserhoff, Anja-Katrin and Oefner, Peter J. (2008) Quantitative analysis of 5'-deoxy-5'-methylthioadenosine in melanoma cells by liquid chromatography-stable isotope ratio tandem mass spectrometry. Journal of Chromatography B 876 (1), pp. 123-128. Fulltext not available.

Gronwald, Wolfram, Klein, M. S., Kaspar, Hannelore, Fagerer, S. R., Nürnberger, N., Dettmer, Katja , Bertsch, T. and Oefner, Peter J. (2008) Urinary metabolite quantification employing 2D NMR spectroscopy. Anal. Chem. 80 (23), pp. 9288-9297. Fulltext not available.

2007

Dettmer, Katja, Aronov, P. A. and Hammock, B. D. (2007) Mass spectrometry-based metabolomics. Mass Spectrometry Reviews (Mass Spectrom Rev) 26 (1), pp. 51-78. Fulltext not available.

Dettmer, Katja , Hanna, D., Whetstone, P., Hansen, R. and Hammock, B. D. (2007) Autism and urinary exogenous neuropeptides: development of an on-line SPE-HPLC-tandem mass spectrometry method to test the opioid excess theory. Analytical and Bioanalytical Chemistry 388 (8), pp. 1643-1651. Fulltext not available.

Dettmer, Katja (2007) On the occasion of Professor Werner Engewald’s 70th birthday. Analytical and Bioanalytical Chemistry 388 (8), pp. 1631-1632. Fulltext not available.

2006

Schmelzer, K. R., Wheelock, A. M., Dettmer, Katja, Morin, D. and Hammock, B. D. (2006) The role of inflammatory mediators in the synergistic toxicity of ozone and 1-nitronaphthalene in rat airways. Environmental Health Perspectives 114 (9), pp. 1354-1360.

Schmelzer, K. R., Wheelock, A. M., Dettmer, Katja, Morin, D. and Hammock, B. D. (2006) The role of inflammatory mediators in the synergistic toxicity of ozone and 1-nitronaphthalene in rat airways. Environmental Health Perspectives (EHP) 114 (9), pp. 1354-1360.

Koivunen, M. E., Dettmer, Katja, Vermeulen, R., Bakke, B., Gee, S. J. and Hammock, B. D. (2006) Improved methods for urinary atrazine mercapturate analysis--assessment of an enzyme-linked immunosorbent assay (ELISA) and a novel liquid chromatography-mass spectrometry (LC-MS) method utilizing online solid phase extraction (SPE). Analytica Chimica Acta 572 (2), pp. 180-189. Fulltext not available.

2005

Aronov, P. A., Dettmer, Katja, Christiansen, J. A., Cornel, A. J. and Hammock, B. D. (2005) Development of a HPLC/tandem-MS method for the analysis of the larvicides methoprene, hydroprene, and kinoprene at trace levels using Diels-Alder derivatization. Journal of Agricultural and Food Chemistry 53 (9), pp. 3306-3312. Fulltext not available.

Beyer, D., Eckerle, P., Cortes, H., Engewald, W. and Dettmer, Katja (2005) Development and applications of an automated in-column pyrolysis gas chromatography mass spectrometry system. Chromatographia 62, pp. 417-422. Fulltext not available.

2004

Dettmer, Katja and Hammock, B. D. (2004) Metabolomics--a new exciting field within the “omics” Sciences. Environmental Health Perspectives 112 (7), A396-397.

2003

Dettmer, Katja and Engewald, W. (2003) Ambient air analysis of volatile organic compounds using adsorptive enrichment. Chromatographia 57 suppl.1, S339-S347. Fulltext not available.

Bothe, F., Dettmer, Katja and Engewald, W. (2003) Determination of perfume oil in household products by geadspace solid-phase microextraction and fast capillary gas chromatography. Chromatographia 57 suppl.1, S190-S206. Fulltext not available.

Drechsel, D., Dettmer, Katja and Engewald, W. (2003) Studies of thermally assisted hydrolysis and methylation-GC-MS of fatty acids and triglycerides using different reagents and injection systems. Chromatographia 57 suppl.1, S283-S289. Fulltext not available.

2002

Dettmer, Katja and Engewald, W. (2002) Adsorbent materials commonly used in air analysis for adsorptive enrichment and thermal desorption of volatile organic compounds. Analytical and Bioanalytical Chemistry 373 (6), pp. 490-500. Fulltext not available.

2001

Dettmer, Katja, Bittner, T. and Engewald, W. (2001) Adsorptive enrichment and thermal desorption of low-boiling oxygenated compounds—possibilities and limitations. Chromatographia 53 suppl.1, S322-S326. Fulltext not available.

Drechsel, D., Dettmer, Katja, Engewald, W., Bittner, T. and Efner, J. (2001) GC analysis of trichloroacetic acid in water samples by large-volume injection and thermal decarboxylation in a programmed-temperature vaporizer. Chromatographia 54, pp. 151-154. Fulltext not available.

2000

Dettmer, Katja, Felix, U., Engewald, W. and Mohnke, M. (2000) Application of a unique selective PLOT capillary column for the analysis of oxygenated compounds in ambient air. Chromatographia 51 Suppl., S221-S227. Fulltext not available.

Dettmer, Katja, Knobloch, T. and Engewald, W. (2000) Stability of reactive low boiling hydrocarbons on carbon based adsorbents typically used for adsorptive enrichment and thermal desorption. Analytical and Bioanalytical Chemistry (Formerly: Fresenius' Journal of Analytical Chemistry 366, pp. 70-78. Fulltext not available.

This list was generated on Fri Apr 17 18:08:05 2026 CEST.
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