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Number of items at this level: 508.

2014

Baumeister, Paul (2014) Molecular tools for G-protein coupled receptors:
Synthesis, pharmacological characterization and [3H]-labeling of subtype-selective ligands for histamine H4 and NPY Y2 receptors.
PhD, Universität Regensburg

Thiele, Karinna Marie (2014) Charakterisierung Gαi3-gendefizienter Mauslinien. PhD, Universität Regensburg

Meyer, Carolin (2014) Synthesis and structure-activity relationships of inhibitors of bacterial hyaluronidase: An approach to obtain compounds with drug-like properties. PhD, Universität Regensburg

Dove, Stefan (2014) Multivariate analysis of hydrophobic descriptors. ADMET & DMPK 2 (1), pp. 3-17.

Dove, Stefan and Danker, Kerstin Yvonne and Stasch, Johannes-Peter and Kaever, Volkhard and Seifert, Roland (2014) Structure/Activity Relationships of (M)ANT- and TNP-Nucleotides for Inhibition of Rat Soluble Guanylyl Cyclase alpha(1)beta(1). Molecular Pharmacology 85 (4), pp. 598-607.

Bauer, Stefanie (2014) Quinoline carboxamides as modulators of Breast Cancer Resistance Protein (ABCG2): Investigations on potency, selectivity, mechanism of action, cytotoxicity, stability and drug-like properties. PhD, Universität Regensburg

Rothenhöfer, Martin (2014) Analytical approaches to the study of hyaluronan and hyaluronidases: Development and application of hyphenated chromatographic and electrophoretic methods. PhD, Universität Regensburg

Baumeister, Paul and Erdmann, Daniela and Biselli, Sabrina and Kagermeier, Nicole and Elz, Sigurd and Bernhardt, Günther and Buschauer, Armin (2014) 3HUR-DE257: Development of a tritium-labeled squaramide-type selective histamine H2 receptor antagonist. ChemMedChem. (In Press)

Pollinger, Klaus and Hennig, Robert and Bauer, Stefanie and Breunig, Miriam and Tessmar, Joerg and Buschauer, Armin and Witzgall, Ralph and Göpferich, Achim (2014) Biodistribution of quantum dots in the kidney after intravenous injection. Journal of Nanoscience and Nanotechnology 14 (5), pp. 3313-3319.

Cuboni, Serena and Devigny, Christian and Hoogeland, Bastiaan and Strasser, Andrea and Pomplun, Sebastian and Hauger, Barbara and Höfner, Georg and Wanner, Klaus and Eder, Matthias and Buschauer, Armin and Holsboer, Florian and Hausch, Felix (2014) Loratadine and analogs: Discovery and preliminary SAR of inhibitors of the amino acid transporter B0AT2. Journal of Medicinal Chemistry. (In Press)

Wittmann, Hans-Joachim and Seifert, Roland and Strasser, Andrea (2014) Mathematical analysis of the sodium sensitivity of the human histamine H3 receptor. In silico pharmacology 2.

Wifling, David and Löffel, Karolin and Nordemann, Uwe and Strasser, Andrea and Bernhardt, Günther and Dove, Stefan and Seifert, Roland and Buschauer, Armin (2014) Molecular determinants for the high constitutive activity of the human histamine H4 receptor: Functional studies on orthologs and mutants. British Journal of Pharmacology. (In Press)

Werner, Kristin and Neumann, Detlef and Buschauer, Armin and Seifert, Roland (2014) No evidence for histamine H4-receptor in human monocytes. Journal of Pharmacology and Experimental Therapeutics 351 (3), pp. 519-526.

Wager, Eva and Wittmann, Hans-Joachim and Elz, Sigurd and Strasser, Andrea (2014) Pharmacological profile of astemizole-derived compounds at the histamine H1 and H4 receptor - H1/H4 receptor selectivity. Naunyn-Schmiedeberg's Archives of Pharmacology 387, pp. 235-250.

Wittmann, Hans-Joachim and Seifert, Roland and Strasser, Andrea (2014) Sodium binding to hH3R and hH4R - a molecular modelling study. Journal of Molecular Modeling 20, p. 2394.

Geyer, Roland and Kaske, Melanie and Baumeister, Paul and Buschauer, Armin (2014) Synthesis and functional characterization of imbutamine analogs as histamine H3 and H4 receptor ligands. Archiv der Pharmazie (Weinheim, Germany) 347 (2), pp. 77-88.

Geyer, Roland and Igel, Patrick and Kaske, Melanie and Elz, Sigurd and Buschauer, Armin (2014) Synthesis, SAR and selectivity of 2-acyl- and 2-cyano-1-hetarylalkyl-guanidines at the four histamine receptor subtypes: a bioisosteric approach. MedChemComm 5 (1), pp. 72-81.

2013

Schickaneder, Helmut and Buschauer, Armin and Bernhardt, Günther and Schickaneder, Christian and Limmert, Michael and Huber, Stefan and Lubbe, Mathias and Hofmeier, Harald (2013) Esters of bendamustine and related compounds, and medical use thereof.

Sadek, Bassem and Alisch, Rudi and Buschauer, Armin and Elz, Sigurd (2013) Synthesis and dual histamine H1 and H2 receptor antagonist activity of cyanoguanidine derivatives. Molecules 18 (11), pp. 14186-14202.

Dove, Stefan and Buschauer, Armin (2013) G-Protein-gekoppelte Rezeptoren: „Sinnesorgane“ der Zellen. Blick in die Wissenschaft 22 (28), pp. 3-9.

Schreeb, Annemarie and Łażewska, Dorota and Dove, Stefan and Buschauer, Armin and Kieć-Kononiwcz, Katarzyna and Stark, Holger (2013) 2. Histamine H4 receptor ligands. In: Stark, Holger, (ed.) Histamine H4 receptor: a novel drug target for immunoregulation and inflammation. Versita, London, pp. 21-62. ISBN 9788376560564.

Keller, Max and Kaske, Melanie and Holzammer, Tobias and Bernhardt, Günther and Buschauer, Armin (2013) Dimeric argininamide-type neuropeptide Y receptor antagonists: chiral discrimination between Y1 and Y4 receptors. Bioorganic and Medicinal Chemistry 21 (21), pp. 6303-6322.

Berlicki, Lukasz and Kaske, Melanie and Gutierrez-Abad, Raquel and Bernhardt, Günther and Illa, Ona and Ortuño, Rosa and Cabrele, Chiara and Buschauer, Armin and Reiser, Oliver (2013) Replacement of Thr32 and Gln34 in the C-terminal neuropeptide Y fragment 25-36 by cis-cyclobutane- and cis-cyclopentane β-amino acids shifts selectivity toward the Y4 receptor. Journal of Medicinal Chemistry 56 (21), pp. 8422-8431.

Textor, Christian (2013) Small molecules as inhibitors of streptococcal hyaluronidase: a computer-assisted and multicomponent synthesis approach. PhD, Universität Regensburg

Nordemann, Uwe and Wifling, David and Schnell, David and Bernhardt, Günther and Stark, Holger and Seifert, Roland and Buschauer, Armin (2013) Luciferase reporter gene assay on human, murine and rat histamine H4 receptor orthologs: correlations and discrepancies between distal and proximal readouts. PLoS One 8 (9), e73961.

Bauer, Stefanie and Ochoa Puentes, Cristian and Sun, Qiu and Bause, Manuel and Bernhardt, Günther and König, Burkhard and Buschauer, Armin (2013) Quinoline carboxamide-type ABCG2 modulators: Indole and quinoline moieties as anilide replacements. ChemMedChem 8 (11), pp. 1773-1778.

Holzammer, Tobias (2013) Homology modeling, molecular dynamics simulations and site-directed mutagenesis of histamine H2 receptors. PhD, Universität Regensburg

Kaske, Melanie (2013) In search for potent and selective NPY Y4 receptor ligands: acylguanidines, argininamides and peptide analogs. PhD, Universität Regensburg

Brunskole Hummel, Irena and Kälble, Solveig and Burhenne, Heike and Reinartz, Michael T. and Schwede, Frank and Buschauer, Armin and Seifert, Roland (2013) Dissociations in the effects of beta2-adrenergic receptor agonists on cAMP formation and superoxide production in human neutrophils: Support for the concept of functional selectivity. PLoS One 8 (5), e64556.

Hamberger, Janina (2013) Characterization of mammalian hyaluronidase-2 activity and identification of inhibitors of Streptococcal hyaluronan lyase. PhD, Universität Regensburg

Ochoa-Puentes, Cristian and Bauer, Stefanie and Kühnle, Matthias and Bernhardt, Günther and Buschauer, Armin and König, Burkhard (2013) Benzanilide – Biphenyl Replacement: A Bioisosteric Approach to Quinoline Carboxamide-type ABCG2 Modulators. ACS Medicinal Chemistry Letters 4 (4), pp. 393-396.

Pluym, Nikola and Baumeister, Paul and Keller, Max and Bernhardt, Günther and Buschauer, Armin (2013) [3H]UR-PLN196: A Selective Nonpeptide Radioligand and Insurmountable Antagonist for the Neuropeptide Y Y2 Receptor. ChemMedChem 8 (4), pp. 587-593.

Seifert, Roland and Strasser, Andrea and Schneider, Erich H. and Neumann, Detlef and Dove, Stefan and Buschauer, Armin (2013) Molecular and cellular analysis of human histamine receptor subtypes. Trends in Pharmacological Sciences 34 (1), pp. 33-58.

Strasser, Andrea and Wittmann, Hans-Joachim and Buschauer, Armin and Schneider, Erich H. and Seifert, Roland (2013) Species-dependent activities of GPCR ligands: Lessons from histamine receptor orthologs. Trends in Pharmacological Sciences 34 (1), pp. 13-32.

Seifert, Roland and Dove, Stefan (2013) Inhibitors of Bacillus anthracis edema factor. Pharmacology & Therapeutics 140 (2), pp. 200-212.

Strasser, Andrea and Wittmann, Hans-Joachim (2013) Modelling of GPCRs - A Practical Handbook. Springer.

Strasser, Andrea and Wittmann, Hans-Joachim (2013) Molecular modelling studies give hint for the existence of a symmetric hb2R-Gabg-homodimer. J Mol Model 19, pp. 4443-4457.

Nordemann, Uwe (2013) Radioligand binding and reporter gene assays for histamine H3 and H4 receptor species orthologs. PhD, Universität Regensburg

Bodensteiner, Julian and Baumeister, Paul and Geyer, Roland and Buschauer, Armin and Reiser, Oliver (2013) Synthesis and pharmacological characterization of new tetrahydrofuran based compounds as conformationally constrained histamine receptor ligands. Organic & biomolecular chemistry 11 (24), pp. 4040-55.

2012

Ertel, Miriam and Bernhardt, Günther and Nink, Jörg and Buschauer, Armin (2012) Novel prodrugs of (1S,9S)-9-[[(1S)-1-carboxy-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid and their use in transdermal therapeutic systems.

Memminger, Martin and Keller, Max and Lopuch, Miroslaw and Pop, Nathalie and Bernhardt, Günther and von Angerer, Erwin and Buschauer, Armin (2012) The Neuropeptide Y Y1 receptor: a diagnostic marker? Expression in MCF-7 breast cancer cells is down-regulated by antiestrogens in vitro and in xenografts. PLoS ONE 7 (12), e51032.

Löber, Stefan and Hübner, Harald and Buschauer, Armin and Sanna, Fabrizio and Argiolas, Antonio and Melis, Maria Rosaria and Gmeiner, Peter (2012) Novel azulene derivatives for the treatment of erectile dysfunction. Bioorganic & medicinal chemistry letters 22 (23), pp. 7151-7154.

Rothenhöfer, Martin and Scherübl, Rosmarie and Bernhardt, Günther and Heilmann, Jörg and Buschauer, Armin (2012) Qualitative and quantitative analysis of hyaluronan oligosaccharides with high performance thin layer chromatography using reagent-free derivatization on amino-modified silica and electrospray ionization-quadrupole time-of-flight mass spectrometry coupling on normal phase. Journal of chromatography. A 1248, pp. 169-77.

Ertel, Miriam (2012) Ambivalence of drug metabolism: Exploration of cilazapril and candesartan prodrugs for transdermal delivery and search for toxic reactive intermediates of N(G)-acylated hetarylpropylguanidines. PhD, Universität Regensburg

Reher, Till M. and Neumann, Detlef and Buschauer, Armin and Seifert, Roland (2012) Incomplete activation of human eosinophils via the histamine H(4)-receptor: Evidence for ligand-specific receptor conformations. Biochemical Pharmacology 84 (2), pp. 192-203.

Seifert, Roland and Dove, Stefan (2012) 3/14. Molecular analysis of agonist stereoisomers at β2-adrenoceptors. In: Jozwiak , Krzysztof and Lough, W. John and Wainer, Irving W., (eds.) Drug stereochemistry : Analytical methods and pharmacology. 3. ed. Informa Healthcare, New York, pp. 274-293. ISBN 9781420092387.

Birnkammer, Tobias and Spickenreither, Anja and Brunskole, Irena and Lopuch, Miroslaw and Kagermeier, Nicole and Bernhardt, Günther and Dove, Stefan and Seifert, Roland and Elz, Sigurd and Buschauer, Armin (2012) The bivalent ligand approach leads to highly potent and selective acylguanidine-type histamine H2 receptor agonists. Journal of Medicinal Chemistry 55 (3), pp. 1147-1160.

Göttle, Martin and Dove, Stefan and Seifert, Roland (2012) Bacillus anthracis edema factor substrate specificity: evidence for new modes of action. Toxins 4 (7), pp. 505-535.

Grundmann, Marco and Rothenhöfer, M. and Bernhardt, Günther and Buschauer, Armin and Matysik, Frank-Michael (2012) Fast counter-electroosmotic capillary electrophoresis-time-of-flight mass spectrometry of hyaluronan oligosaccharides. Analytical and Bioanalytical Chemistry : Anal. Bioanal. Chem. 402, pp. 2617-2623.

Posavec, Damir and Zabel, Manfred and Bogner, Udo and Bernhardt, Günther and Knör, Günther (2012) Functionalized derivatives of 1,4-dimethylnaphthalene as precursors for biomedical applications: synthesis, structures, spectroscopy and photochemical activation in the presence of dioxygen. Organic & biomolecular chemistry 10 (35), pp. 7062-7069.

Taha, Hesham and Dove, Stefan and Geduhn, Jens and König, Burkhard and Shen, Yuequan and Tang, Wei-Jen and Seifert, Roland (2012) Inhibition of the adenylyl cyclase toxin, edema factor, from Bacillus anthracis by a series of 18 monoand bis-(M)ANT-substituted nucleoside 5′-triphosphates. Naunyn-Schmiedeberg's Archives of Pharmacology (385), pp. 57-68.

Appl, Heidrun and Holzammer, Tobias and Dove, Stefan and Haen, Ekkehard and Strasser, Andrea and Seifert, Roland (2012) Interactions of recombinant human histamine H₁R, H₂R, H₃R, and H₄R receptors with 34 antidepressants and antipsychotics. Naunyn-Schmiedeberg's archives of pharmacology 385 (2), pp. 145-170.

Bernat, Viachaslau and Heinrich, Markus and Baumeister, Paul and Buschauer, Armin and Tschammer, Nuska (2012) Synthesis and application of the first radioligand targeting the allosteric binding pocket of chemokine receptor CXCR3. ChemMedChem 7 (8), pp. 1481-1489.

Seifert, Roland and Dove, Stefan (2012) Towards selective inhibitors of adenylyl cyclase toxin from Bordetella pertussis. Trends in microbiology 20 (7), pp. 343-351.

Strasser, Andrea and Wittmann, Hans-Joachim (2012) hb2R-Gas-complex: Prediction versus crystal structure - How valuable are predictions based on molecular modelling studies? Journal of Molecular Modeling : J Mol Model 18, pp. 3439-3444.

2011

Brunskole, Irena (2011) Molecular and cellular analysis of aminergic G protein-coupled receptors: histamine H2, H4 and β2-adrenergic receptors, a scientific paradigm. PhD, Universität Regensburg

Geyer, Roland (2011) Hetarylalkyl(aryl)cyanoguanidines as histamine H4 receptor ligands: Synthesis, chiral separation, pharmacological characterization, structure-activity and -selectivity relationships. PhD, Universität Regensburg

Pluym, Nikola (2011) Application of the guanidine–acylguanidine bioisosteric approach to NPY Y2 receptor antagonists: bivalent, radiolabeled and fluorescent pharmacological tools. PhD, Universität Regensburg

Birnkammer, Tobias (2011) Highly potent and selective acylguanidine-type histamine H2 receptor agonists: synthesis and structure-activity relationships of mono- and bivalent ligands. PhD, Universität Regensburg

Lopuch, Miroslaw (2011) Investigations on neuropeptide Y and histamine receptors by fluorescence-based and radiochemical methods. PhD, Universität Regensburg

Brunskole, Irena and Strasser, Andrea and Seifert, Roland and Buschauer, Armin (2011) Role of the second and third extracellular loops of the histamine H4 receptor in receptor activation. Naunyn-Schmiedeberg's Archives of Pharmacology 384 (3), pp. 301-317.

Braun, Stephan and Botzki, Alexander and Salmen, Sunnhild and Textor, Christian and Bernhardt, Günther and Dove, Stefan and Buschauer, Armin (2011) Design of benzimidazole- and benzoxazole-2-thione derivatives as inhibitors of bacterial hyaluronan lyase. European Journal of Medicinal Chemistry 46 (9), pp. 4419-4429.

Pluym, Nikola and Brennauer, Albert and Keller, Max and Ziemek, Ralf and Pop, Nathalie and Bernhardt, Günther and Buschauer, Armin (2011) Application of the guanidine – acylguanidine bioisosteric approach to argininamide-type NPY Y2 receptor antagonists. ChemMedChem 6 (9), pp. 1727-1738.

Posavec, Damir (2011) Adjustment of the decay kinetics of photogenerated endoperoxides embedded in various carrier materials aiming at medical applications. PhD, Universität Regensburg

Geyer, Roland and Buschauer, Armin (2011) Synthesis and histamine H3 and H4 receptor activity of conformationally restricted cyanoguanidines related to UR-PI376. Archiv der Pharmazie 344 (12), pp. 775-785.

Keller, Max and Bernhardt, Günther and Buschauer, Armin (2011) [3H]UR-MK136 - a highly potent and selective radioligand for neuropeptide Y Y1 receptors. ChemMedChem 6 (9), pp. 1566-1571.

Pop, Nathalie and Igel, Patrick and Brennauer, Albert and Cabrele, Chiara and Bernhardt, Günther and Seifert, Roland and Buschauer, Armin (2011) Functional reconstitution of human neuropeptide Y (NPY) Y2 and Y4 receptors in Sf9 insect cells. Journal of Receptors and Signal Transduction 31 (4), pp. 271-285.

Keller, Max and Erdmann, Daniela and Teng, Shangjun and Pop, Nathalie and Pluym, Nikola and Bernhardt, Günther and Buschauer, Armin (2011) Red-fluorescent argininamide-type NPY Y(1) receptor antagonists as pharmacological tools. Bioorganic & Medicinal Chemistry 19 (9), pp. 2859-2878.

Schnell, David and Brunskole, Irena and Ladova, Katerina and Schneider, Erich H. and Igel, Patrick and Dove, Stefan and Buschauer, Armin and Seifert, Roland (2011) Expression and functional properties of canine, rat and murine histamine H4-receptors in Sf9 insect cells. Naunyn-Schmiedeberg's Archives of Pharmacology 383 (5), pp. 457-470.

Seifert, Roland and Schneider, Erich H. and Dove, Stefan and Brunskole, Irena and Neumann, Detlef and Strasser, Andrea and Buschauer, Armin (2011) Paradoxical stimulatory effects of the “standard” histamine H4-receptor antagonist JNJ7777120: The H4-receptor joins the club of 7TM receptors exhibiting functional selectivity. Molecular Pharmacology 79 (4), pp. 631-638.

Geduhn, Jens and Dove, Stefan and Shen, Yuequan and Tang, Wei-Jen and König, Burkhard and Seifert, Roland (2011) Bis-Halogen-Anthraniloyl-Substituted Nucleoside 5'-triphosphates as Potent and Selective Inhibitors of Bordetella pertussis CyaA. The Journal of pharmacology and experimental therapeutics 336 (1), pp. 104-115.

Silva, Maria Elena and Heim, Ralf and Strasser, Andrea and Elz, Sigurd and Dove, Stefan (2011) Theoretical studies on the interaction of partial agonists with the 5-HT(2A) receptor. Journal of computer-aided molecular design 25 (1), pp. 51-66.

Erdmann, Daniela (2011) Histamine H2- and H3-receptor antagonists: Synthesis and characterization of radiolabelled and fluorescent pharmacological tools. PhD, Universität Regensburg

Wittmann, Hans-Joachim and Seifert, Roland and Strasser, Andrea (2011) Influence of the N-terminus and the E2-loop onto the binding kinetics of the antagonist mepyramine and the partial agonist phenoprodifen to H1R. Biochemical Pharmacology 12, pp. 1910-1918.

Wittmann, Hans-Joachim and Elz, Sigurd and Seifert, Roland and Strasser, Andrea (2011) Na-methylated phenylhistamines exhibit affinity to the hH4R - a pharmacological and molecular modelling study. Naunyn Schmiedeberg's Arch Pharmacol 384, pp. 287-299.

Posavec, Damir and Dorsch, Andre and Bogner, Udo and Bernhardt, Guenther and Nagl, Stefan (2011) Polyvinyl butyral nanobeads: preparation, characterization, biocompatibility and cancer cell uptake. Microchimica acta 173 (3-4), pp. 391-399.

Ochoa Puentes, Cristian and Höcherl, Peter and Kühnle, Matthias and Bauer, Stefanie and Kürger, Kira and Bernhardt, Günther and Buschauer, Armin and König, Burkhard (2011) Solid phase synthesis of tariquidar-related modulators of ABC transporters preferring breast cancer resistance protein (ABCG2). Bioorganic & Medicinal Chemistry Letters 21 (12), pp. 3654-3657.

Weiss, Stefan and Bernhardt, Günther and Buschauer, Armin and König, Burkhard (2011) Synthesis and characterization of DMAP-Modified NPY Y1 receptor antagonists as acyl-transfer catalysts. Collection of Czechoslovak chemical communications 76 (6), 763 -780.

2010

Igel, Patrick and Dove, Stefan and Buschauer, Armin (2010) Histamine H4 receptor agonists. Bioorganic & Medicinal Chemistry Letters 20 (24), pp. 7191-7199.

Pop, Nathalie (2010) Development of functional assays for human neuropeptide Y (Y1,2,4,5) receptors exploiting GTPase activity and (bio)luminescence as readout. PhD, Universität Regensburg

Höcherl, Peter (2010) New tariquidar-like ABCB1 modulators in cancer chemotherapy:
Preclinical pharmacokinetic, pharmacodynamic investigations and computational studies.
PhD, Universität Regensburg

Hild, Wolfgang and Pollinger, Klaus and Caporale, Andrea and Cabrele, Chiara and Keller, Max and Pluym, Nicola and Buschauer, Armin and Rachel, Reinhard and Tessmar, Joerg and Breunig, Miriam and Goepferich, Achim (2010) G protein-coupled receptors function as logic gates for nanoparticle binding and cell uptake. Proceedings of the National Academy of Sciences USA: PNAS 107 (23), pp. 10667-10672.

Ghorai, Prasanta and Kraus, Anja and Birnkammer, Tobias and Geyer, Roland and Bernhardt, Günther and Dove, Stefan and Seifert, Roland and Elz, Sigurd and Buschauer, Armin (2010) Chiral N(G)-acylated hetarylpropylguanidine-type histamine H2 receptor agonists do not show significant stereoselectivity. Bioorganic & Medicinal Chemistry Letters 20 (10), pp. 3173-3176.

Kühnle, Matthias (2010) Experimental therapy and detection of glioblastoma: investigation of nanoparticles, ABCG2 modulators and optical imaging of intracerebral xenografts. PhD, Universität Regensburg

Dayoub, Rania (2010) Expression and regulation of liver regeneration associated protein ALR under patho-physiological conditions. PhD, Universität Regensburg

Strasser, Andrea and Wittmann , Hans-Joachim (2010) 3D-QSAR CoMFA study to predict orientation of suprahistaprodifens and phenoprodifens in the binding-pocket of four histamine H1-receptor species. Molecular Informatics 29, pp. 333-341.

Kleinmaier, R. and Igel, P. and Keller, M. and Buschauer, Armin and Gschwind, R. M. (2010) Conformations, Conformational Preferences, and Conformational Exchange of N'-Substituted N-Acylguanidines: Intermolecular Interactions Hold the Key. J. Am. Chem. Soc. 132 (32), pp. 11223-11233.

Strasser, Andrea and Wittmann, Hans-Joachim (2010) Distinct interactions between the human adrenergic b2 receptor and Gas - an in silico study. J Mol Model 16, pp. 1307-1318.

Schneider, Erich H. and Schnell, David and Strasser, Andrea and Dove, Stefan and Seifert, Roland (2010) Impact of the DRY Motif and the Missing "Ionic Lock" on Constitutive Activity and G-Protein Coupling of the Human Histamine H-4 Receptor. Journal of Pharmacology and Experimental Therapeutics 333 (2), pp. 382-392.

Strasser, Andrea and Wittmann, Hans-Joachim (2010) In silico analysis of the histaprodifen induced pathway of the guinea-pig histamine H1 receptor. Journal of computer- aided molecular design : J Comput Aided Mol Des 24, pp. 759-769.

Weiss, Stefan and Keller, Max and Bernhardt, G. and Buschauer, Armin and König, Burkhard (2010) N(G)-Acyl-argininamides as NPY Y (1) receptor antagonists: Influence of structurally diverse acyl substituents on stability and affinity. Bioorganic & Medicinal Chemistry (18), pp. 6292-6304.

2009

Mosandl, Johannes (2009) Radiochemical and luminescence-based binding and functional assays for human histamine receptors using genetically engineered cells. PhD, Universität Regensburg

Igel, Patrick and Geyer, Roland and Straßer, Andrea and Dove, Stefan and Seifert, Roland and Buschauer, Armin (2009) Synthesis and structure-activity relationships of cyanoguanidine-type and structurally related histamine H(4) receptor agonists. Journal of Medicinal Chemistry 52 (20), pp. 6297-6313.

Keller, Max and Teng, Shangjun and Bernhardt, Günther and Buschauer, Armin (2009) Bivalent argininamide-type neuropeptide Y Y1 antagonists do not support the hypothesis of receptor dimerisation. ChemMedChem 4 (10), pp. 1733-1745.

Memminger, Martin (2009) Synthesis and characterization of subtype-selective estrogen receptor ligands and their application as pharmacological tools - Cross-talk between estrogen and NPY Y1 receptors in human breast cancer cells. PhD, Universität Regensburg

Igel, Patrick and Schneider, Erich and Schnell, David and Elz, Sigurd and Seifert, Roland and Buschauer, Armin (2009) N(G)-Acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent. Journal of Medicinal Chemistry 52 (8), pp. 2623-2627.

Kraus, Anja and Ghorai, Prasanta and Birnkammer, Tobias and Schnell, David and Elz, Sigurd and Seifert, Roland and Dove, Stefan and Bernhardt, Günther and Buschauer, Armin (2009) N(G)-Acylated aminothiazolylpropylguanidines as potent and selective histamine H2 receptor agonists. ChemMedChem 4 (2), pp. 232-240.

Igel, Patrick and Schnell, David and Bernhardt, Günther and Seifert, Roland and Buschauer, Armin (2009) Tritium-labeled N1-[3-(1H-imidazol-4-yl)propyl]-N2-propionylguanidine ([3H]UR-PI294), a high affinity histamine H3 and H4 receptor radioligand. ChemMedChem 4 (2), pp. 225-231.

Kühnle, Matthias and Egger, Michael and Müller, Christine and Mahringer, Anne and Bernhardt, Günther and Fricker, Gert and König, Burkhard and Buschauer, Armin (2009) Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar. Journal of Medicinal Chemistry 52 (4), pp. 1190-1197.

Keller, Max (2009) Guanidine-acylguanidine bioisosteric approach to address peptidergic receptors: pharmacological and diagnostic tools for the NPY Y1 receptor and versatile building blocks based on arginine substitutes. PhD, Universität Regensburg

Igel, Patrick (2009) Synthesis and structure-activity relationships of NG-acylated arylalkylguanidines and related compounds as histamine receptor ligands: searching for selective H4R agonists. PhD, Universität Regensburg

Wittmann, Hans-Joachim and Seifert, Roland and Strasser, Andrea (2009) Contribution of binding enthalpy and entropy to affinity of antagonist and agonist binding at human and guinea pig histamine H1-receptor. Molecular Pharmacology 76, pp. 25-37.

Mahboobi, Siavosh and Dove, Stefan and Sellmer, Andreas and Winkler, Matthias and Eichhorn, Emerich and Pongratz, Herwig and Ciossek, Thomas and Baer, Thomas and Maier, Thomas and Beckers, Thomas (2009) Design of chimeric histone deacetylase- and tyrosine kinase-inhibitors: a series of imatinib hybrides as potent inhibitors of wild-type and mutant BCR-ABL, PDGF-Rbeta, and histone deacetylases. Journal of medicinal chemistry 52 (8), pp. 2265-79.

Seifert, Roland and Dove, Stefan (2009) Functional Selectivity of GPCR Ligand Stereoisomers: New Pharmacological Opportunities. Mol. Pharmacol. 75 (1), pp. 13-18.

Taha, H. M. and Schmidt, J. and Göttle, M. and Suryanarayana, S. and Shen, Y. and Tang, W.-J. and Gille, A. and Geduhn, Jens and König, Burkhard and Dove, Stefan and Seifert, Roland (2009) Molecular Analysis of the Interaction of Anthrax Adenylyl Cyclase Toxin, Edema Factor, with 2'(3')-O-(N-(methyl)anthraniloyl)-Substituted Purine and Pyrimidine Nucleotides. Mol. Pharmacol. 75 (3), pp. 693-703.

Strasser, Andrea (2009) Molecular Modelling and QSAR-based design of histamine receptor ligands. Expert Opinion on Drug Discovery (4), pp. 1061-1075.

2008

Keller, Max and Pop, Nathalie and Hutzler, Christoph and Beck-Sickinger, Annette G. and Bernhardt, Günther and Buschauer, Armin (2008) Guanidine - acylguanidine bioisosteric approach in the design of radioligands: Synthesis of a tritium-labeled N(G)-propionylargininamide ([3H]UR-MK114) as a highly potent and selective neuropeptide Y Y1 receptor antagonist. Journal of Medicinal Chemistry 51 (24), pp. 8168-8172.

Ghorai, Prasanta and Kraus, Anja and Keller, Max and Götte, Carsten and Igel, Patrick and Schneider, Erich and Schnell, David and Bernhardt, Günther and Dove, Stefan and Zabel, Manfred and Elz, Sigurd and Seifert, Roland and Buschauer, Armin (2008) Acylguanidines as bioisosteres of guanidines: N(G)-acylated imidazolylpropylguanidines, a new class of histamine H2 receptor agonists. Journal of Medicinal Chemistry 51 (22), pp. 7193-7204.

Weiss, Stefan and Keller, Max and Bernhardt, Günther and Buschauer, Armin and König, Burkhard (2008) Modular synthesis of non-peptidic bivalent NPY Y(1) receptor antagonists. Bioorganic & Medicinal Chemistry 16 (22), pp. 9858-9866.

Kraus, Anja (2008) Highly potent, selective acylguanidine-type histamine H2 receptor agonists: synthesis and structure-activity relationships. PhD, Universität Regensburg

Spickenreither, Martin (2008) Inhibitors of bacterial and mammalian hyaluronidases: design, synthesis and structure-activity relationships with focus on human enzymes. PhD, Universität Regensburg

Vogel, Susanne and Kaufmann, Doris and Pojarová, Michaela and Müller, Christine and Pfaller, Tobias and Kühne, Sybille and Bednarski, Patrick J and Angerer, Erwin von (2008) Aroyl hydrazones of 2-phenylindole-3-carbaldehydes as novel antimitotic agents. Bioorganic & Medicinal Chemistry 16 (12), pp. 6436-6447.

Kutta, Roger J. and Hofinger, Edith S. A. and Preuss, Hendrik and Bernhardt, Günther and Dick, Bernhard (2008) Blue-light induced interaction of LOV domains from Chlamydomonas reinhardtii. Chembiochem : a European journal of chemical biology 9 (12), pp. 1931-1938.

Hubensack, Martina and Müller, Christine and Höcherl, Höcherl and Fellner, Stephan and Spruss, Thilo and Bernhardt, Günther and Buschauer, Armin (2008) Effect of the ABCB1 modulators elacridar and tariquidar on the distribution of paclitaxel in nude mice. Journal of Cancer Research and Clinical Oncology 134 (5), pp. 597-607.

Dove, Stefan and Seifert, Roland and Elz, Sigurd and Buschauer, Armin (2008) Frontiers in medicinal chemistry in Regensburg. ChemMedChem 3 (8), pp. 1181-1184.

Hofinger, Edith S. A. and Hoechstetter, Julia and Oettl, Martin and Bernhardt, Günther and Buschauer, Armin (2008) Isoenzyme-specific differences in the degradation of hyaluronic acid by mammalian-type hyaluronidases. Glycoconjugate Journal 25 (2), pp. 101-109.

Strasser, Andrea and Wittmann, Hans-Joachim and Seifert, Roland (2008) Ligand-specific contribution of the N-terminus and E2-loop to pharmacological properties of the histamine H1-receptor. J Pharmacol Exp Ther : The journal of pharmacology and experimental therapeutics 326 (3), pp. 783-791.

Dai, Jisen and Jian, Jinlong and Bosland, Maarten and Frenkel, Krystyna and Bernhardt, Günther and Huang, Xi (2008) Roles of hormone replacement therapy and iron in proliferation of breast epithelial cells with different estrogen and progesterone receptor status. Breast (Edinburgh, Scotland) 17 (2), pp. 172-179.

Bernhardt, Günther and Biersack, Bernhard and Bollwein, Susanne and Schobert, Rainer and Zoldakova, Miroslava (2008) Terpene conjugates of diaminedichloridoplatinum(II) complexes: antiproliferative effects in HL-60 leukemia, 518A2 melanoma, and HT-29 colon cancer cells. Chemistry & biodiversity 5 (8), pp. 1645-1659.

2007

Kiewitz, Sebastian Donatus (2007) Structural investigations of the Id helix-loop-helix dimerization domain. PhD, Universität Regensburg

Göttle, Martin and Dove, Stefan and Steindel, Phillip and Shen, Yuequan and Tang, Wei-Jen and Geduhn, Jens and König, Burkhard and Seifert, Roland (2007) Molecular Analysis of the Interaction of Bordetella pertussis Adenylyl Cyclase with Fluorescent Nucleotides. Molecular Pharmacology 72 (3), pp. 526-535.

Preuß, Hendrik (2007) Species-selective interactions of histamine H2 receptors with guanidine-type agonists: molecular modelling, site-directed mutagenesis and pharmacological analysis. PhD, Universität Regensburg

Müller, Christine (2007) New approaches to the therapy of glioblastoma: investigations on RNA interference, kinesin Eg5 and ABCB1/ABCG2 inhibition. PhD, Universität Regensburg

Colombo, Noemi (2007) Synthesis and conformational analysis of polypeptides related to the inhibitor of the DNA binding and cell differentiation Id2. PhD, Universität Regensburg

Svobodová, Jaroslava (2007) Id3, inhibitor of DNA binding and cell differentiation: synthesis and conformational analysis of the full-length protein and its truncated analogues. PhD, Universität Regensburg

Hofinger, Edith (2007) Recombinant expression, purification and characterization of human hyaluronidases. PhD, Universität Regensburg

Preuss, Hendrik and Ghorai, Prasanta and Kraus, Anja and Dove, Stefan and Buschauer, Armin and Seifert, Roland (2007) Constitutive Activity and Ligand Selectivity of Human,
Guinea Pig, Rat, and Canine Histamine H₂ Receptors.
Journal of Pharmacology and Experimental Therapeutics 321 (3), pp. 983-995.

Preuss, Hendrik and Ghorai, Prasanta and Kraus, Anja and Dove, Stefan and Buschauer, Armin and Seifert, Roland (2007) Mutations of Cys-17 and Ala-271 in the Human Histamine H₂
Receptor Determine the Species Selectivity of Guanidine-Type Agonists and Increase Constitutive Activity.
Journal of Pharmacology and Experimental Therapeutics 321 (3), pp. 975-982.

Strasser, Andrea and Wittmann, Hans-Joachim (2007) Analysis of the activation mechanism of the guinea-pig histamine H1-receptor. J Comput Aided Mol Des : Journal of computer aided molecular design 21, pp. 499-509.

Kaufmann, Doris and Pojarová, Michaela and Vogel, Susanne and Liebl, Renate and Gastpar, Robert and Gross, Dietmar and Nishino, Tsuyuki and Pfaller, Tobias and Angerer, Erwin von (2007) Antimitotic activities of 2-phenylindole-3-carbaldehydes in human breast cancer cells. Bioorganic & medicinal chemistry 15 (15), pp. 5122-36.

Brennauer, Albert and Keller, Max and Freund, Matthias and Bernhardt, Günther and Buschauer, Armin (2007) Decomposition of 1-(w-aminoalkanoyl)guanidines under alkaline conditions. Tetrahedron Letters 48 (39), pp. 6996-6999.

Ziemek, Ralf and Schneider, Erich and Kraus, Anja and Cabrele, Chiara and Beck-Sickinger, Annette G. and Bernhardt, Günther and Buschauer, Armin (2007) Determination of affinity and activity of ligands at the human neuropeptide Y Y4 receptor by flow cytometry and aequorin luminescence. Journal of Receptors and Signal Transduction 27 (4), pp. 217-233.

Xie, Sheng-Xue and Schalkhausser, Fabian and Ye, Qi-Zhuang and Seifert, Roland and Buschauer, Armin (2007) Effects of Impromidine- and Arpromidine-Derived Guanidines on Recombinant Human and Guinea Pig Histamine H₁ and H₂ Receptors. Archiv der Pharmazie 340 (1), pp. 9-16.

Zimmermann, Jochen and Angerer, Erwin von (2007) Estrogenic and antiestrogenic activities of 2,4-diphenylfuran-based ligands of estrogen receptors α and β. The Journal of Steroid Biochemistry and Molecular Biology 104 (3-5), pp. 259-268.

Mahboobi, Siavosh and Uecker, A. and Cénac, C. and Sellmer, A. and Eichhorn, E. and Elz, Sigurd and Böhmer, F.-D. and Dove, Stefan (2007) Inhibition of FLT3 and PDGFR tyrosine kinase activity by bis(benzo[b]furan-2-yl)methanones. Bioorganic & medicinal chemistry 15 (5), pp. 2187-2197.

Müller, Christine and Gross, Dietmar and Sarli, Vasiliki and Gartner, Michael and Giannis, Athanassios and Bernhardt, Günther and Buschauer, Armin (2007) Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells. Cancer Chemotherapy and Pharmacology 59 (2), pp. 157-164.

Hofinger, Edith S. A. and Bernhardt, Günther and Buschauer, Armin (2007) Kinetics of Hyal1 and PH-20 hyaluronidases: comparison of minimal substrates and analysis of the transglycosylation reaction. Glycobiology 17 (9), pp. 963-971.

Strasser, Andrea and Wittmann, Hans-Joachim (2007) LigPath: A module for predictive calculation of a ligands pathway into a receptor - application to the gpH1-receptor. J Mol Model : Journal of molecular modeling 13, pp. 209-218.

Schertl, Sabine and Hartmann, Rolf W. and Batzl-Hartmann, Christine and Spruss, Thilo and Maucher, Anton and Angerer, Erwin von and Schiller, Claus D. and Schneider, Martin R. and Gust, Ronald and Schönenberger, Helmut (2007) Platinum(II) complexes interfering with testicular steroid biosynthesis: drugs for the therapy of advanced or recurrent prostate cancers? Preclinical studies. Journal of Cancer Research and Clinical Oncology 133 (3), pp. 153-167.

Preuss, Hendrik and Ghorai, Prasanta and Kraus, Anja and Dove, Stefan and Buschauer, Armin and Seifert, Roland (2007) Point Mutations in the Second Extracellular Loop of the Histamine H2 Receptor do not affect the Species-Selective Activity of Guanidine-Type Agonists. Naunyn Schmiedebergs Arch. Pharmacol. 376 (4), pp. 253-264.

Hofinger, Edith S. A. and Spickenreither, Martin and Oschmann, Jan and Bernhardt, Günther and Rudolph, Rainer and Buschauer, Armin (2007) Recombinant human hyaluronidase Hyal-1: insect cells versus E. coli as expression system and identification of low molecular weight inhibitors. Glycobiology 17 (4), pp. 444-453.

Schobert, Rainer and Bernhardt, Günther and Biersack, Bernhard and Bollwein, Susanne and Fallahi, Magid and Grotemeier, Antje and Hammond, Geoffrey L. (2007) Steroid conjugates of dichloro(6-aminomethylnicotinate)platinum(II): effects on DNA, sex hormone binding globulin, the estrogen receptor, and various breast cancer cell lines. ChemMedChem 2 (3), pp. 333-342.

Schneider, Erich and Keller, Max and Brennauer, Albert and Hoefelschweiger, Bianca K. and Gross, Dietmar and Wolfbeis, Otto S. and Bernhardt, Günther and Buschauer, Armin (2007) Synthesis and Characterization of the First Fluorescent Nonpeptide NPY Y1 Receptor Antagonist. ChemBioChem 8 (16), pp. 1981-1988.

Egger, Michael and Li, Xuqin and Müller, Christine and Bernhardt, Günther and Buschauer, Armin and König, Burkhard (2007) Tariquidar analogues: synthesis by Cu(I)-catalysed N/O–aryl coupling and inhibitory activity against the ABCB1 transporter. European Journal of Organic Chemistry 2007 (16), pp. 2643-2649.

Pojarová, Michaela and Kaufmann, Doris and Gastpar, Robert and Nishino, Tsuyuki and Reszka, Przemyslaw and Bednarski, Patrick J. and Angerer, Erwin von (2007) [(2-Phenylindol-3-yl)methylene]propanedinitriles inhibit the growth of breast cancer cells by cell cycle arrest in G(2)/M phase and apoptosis. Bioorganic & medicinal chemistry 15 (23), pp. 7368-7379.

2006

Brennauer, Albert (2006) Acylguanidines as bioisosteric groups in argininamide-type neuropeptide Y Y1 and Y2 receptor antagonists: synthesis, stability and pharmacological activity. PhD, Universität Regensburg

Schulz, Berta (2006) Untersuchungen zur Opsonin-Aktivität von CRP, SAP, A-beta42 und SAA und deren Rolle bei der Schaumzellbildung. PhD, Universität Regensburg

Ghorai, Prasanta (2006) Arpromidine-related acylguanidines: synthesis and structure-activity relationships of a new class of guanidine-type histamine H2 receptor agonists with reduced basicity. PhD, Universität Regensburg

Gross, Dietmar (2006) New approaches to the chemotherapy of glioblastoma: investigations on doxorubicin nanoparticles, inhibition of PDGF receptors and kinesin Eg5, with emphasis on confocal laser-scanning microscopy. PhD, Universität Regensburg

Ziemek, Ralf (2006) Development of binding and functional assays for the neuropeptide Y Y 2 and Y 4 receptors. PhD, Universität Regensburg

Grandl, Margot (2006) Influence of E-LDL and Ox-LDL on the metabolism of ApoE, cholesterol, sphingolipids and glycosphingolipids as well as on the raft-composition in human macrophages. PhD, Universität Regensburg

Zimmermann, Jochen (2006) Furan- and pyran-based heterocycles as subtype-selective ligands of the estrogen receptor. Synthesis and biological characterisation. PhD, Universität Regensburg

Xie, Sheng-Xue and Kraus, Anja and Ghorai, Prasanta and Ye, Qi-Zhuang and Elz, Sigurd and Buschauer, Armin and Seifert, Roland (2006) N1-(3-Cyclohexylbutanoyl)-N2-[3-(1H-imidazol-4-
yl)propyl]guanidine (UR-AK57), a Potent Partial Agonist for the Human Histamine H1- and H2- Receptors.
Journal of Pharmacology and Experimental Therapeutics 317 (3), pp. 1262-1268.

Wabnitz, Tobias C. and Rizzo, Simona and Götte, Carsten and Buschauer, Armin and Benincori, Tiziana and Reiser, Oliver (2006) Enantioselective hydrogenation of diaryl-substituted a,b-unsaturated nitriles. Tetrahedron Letters 47 (22), pp. 3733-3736.

Schifferer, Rainer (2006) Charakterisierung des zellulären Lipideffluxes von primären, humanen Fibroblasten und Monozyten/Makrophagen. PhD, Universität Regensburg

Braun, Stephan (2006) New inhibitors of bacterial hyaluronidase - synthesis and structure-activity relationships. PhD, Universität Regensburg

Xie, Sheng-Xue and Ghorai, Prasanta and Ye, Qi-Zhuang and Buschauer, Armin and Seifert, Roland (2006) Probing Ligand-Specific Histamine H1- and H2-Receptor
Conformations with NG-Acylated Imidazolylpropylguanidines.
The Journal of Pharmacology and Experimental Therapeutics 317 (1), pp. 139-146.

Schneider, Erich and Mayer, Matthias and Ziemek, Ralf and Li, Liantao and Hutzler, Christoph and Bernhardt, Günther and Buschauer, Armin (2006) A Simple and Powerful Flow Cytometric Method for the Simultaneous Determination of Multiple Parameters at G-Protein-coupled Receptor Subtypes. ChemBioChem 7 (9), pp. 1400-1409.

Rigden, Daniel J. and Botzki, Alexander and Nukui, Masatoshi and Mewbourne, R. Brandon and Lamani, Ejvis and Braun, Stephan and von Angerer, Erwin and Bernhardt, Günther and Dove, Stefan and Buschauer, Armin and Jedrzejas, Mark J. (2006) Design of new benzoxazole-2-thione derived inhibitors of Streptococcus pneumoniae hyaluronan lyase: structure of a complex with a 2-phenylindole. Glycobiology 16 (8), pp. 757-765.

Ziemek, Ralf and Brennauer, Albert and Schneider, Erich and Cabrele, Chiara and Beck-Sickinger, Annette G. and Bernhardt, Günther and Buschauer, Armin (2006) Fluorescence- and luminescence-based methods for the determination of affinity and activity of neuropeptide Y(2) receptor ligands. European Journal of Pharmacology 551 (1-3), pp. 10-8.

Spickenreither, Martin and Braun, Stephan and Bernhardt, Günther and Dove, Stefan and Buschauer, Armin (2006) Novel 6-O-acylated vitamin C derivatives as hyaluronidase inhibitors with selectivity for bacterial lyases. Bioorganic & Medicinal Chemistry Letters 16 (20), pp. 5313-5316.

Mahboobi, Siavosh and Uecker, A. and Sellmer, A. and Cénac, C. and Höcher, H. and Pongratz, H. and Hufsky, H. and Trümpler, A. and Sicker, M. and Heidel, F. and Fischer, T. and Stocking, C. and Elz, Sigurd and Böhmer, F.-D. and Dove, Stefan (2006) Novel bis-(1H-indol-2-yl)-methanones as potent inhibitors of FLT3 and platelet-derived growth factor receptor tyrosine kinase. Journal of Medicinal Chemistry 49 (11), pp. 3101-3115.

Gross, Dietmar and Bernhardt, Günther and Buschauer, Armin (2006) Platelet-derived growth factor receptor independent proliferation of human glioblastoma cells: selective tyrosine kinase inhibitors lack antiproliferative activity. Journal of Cancer Research and Clinical Oncology 132 (9), pp. 589-599.

Xie, Sheng-Xue and Petrache, Georgiana and Schneider, Erich and Ye, Qi-Zhuang and Bernhardt, Günther and Seifert, Roland and Buschauer, Armin (2006) Synthesis and pharmacological characterization of novel fluorescent histamine H2-receptor ligands derived from aminopotentidine. Bioorganic & Medicinal Chemistry Letters 16 (15), pp. 3886-3890.

2005

Maa Bared, Salim (2005) Identification and characterization of ABCA1-interactive proteins and their relevance to atherosclerosis. PhD, Universität Regensburg

Hoechstetter, Julia (2005) Characterisation of bovine testicular hyaluronidase and a hyaluronate lyase from Streptococcus agalactiae. Investigations on the effect of pH on hyaluronan degradation and preclinical studies on the adjuvant administration of the enzymes in cancer chemotherapy. PhD, Universität Regensburg

Pollak, Nils (2005) Die Rolle von MIF (macrophage migration inhibitory factor) in der Sepsis-induzierten Immunparalyse. PhD, Universität Regensburg

Hubensack, Martina (2005) Approaches to overcome the blood-brain barrier in the chemotherapy of primary and secondary brain tumors: Modulation of P-glycoprotein 170 and targeting of the transferrin receptor. PhD, Universität Regensburg

Hantschel, Markus (2005) Durchflusszytometrische Analysen zur Expression des Hitzeschockproteins Hsp70 auf der Zelloberfläche von kolorektalen Primärtumoren und hepatischen Metastasen, Magenkarzinomen, Bronchialkarzinomen, Kopf-Hals-Tumoren und akuten myeloischen Leukämien. PhD, Universität Regensburg

Zimmermann, Jochen and Liebl, Renate and Angerer, Erwin von (2005) 2,5-Diphenylfuran-based pure antiestrogens with selectivity for the estrogen receptor alpha. The Journal of Steroid Biochemistry and Molecular Biology 94 (1-3), pp. 57-66.

Bouchal, Jan and Baumforth, Karl R N and Sváchová, Michaela and Murray, Paul G and Angerer, Erwin von and Kolár, Zdenek (2005) Microarray analysis of bicalutamide action on telomerase activity, p53 pathway and viability of prostate carcinoma cell lines. The Journal of pharmacy and pharmacology 57 (1), pp. 83-92.

Botzki, Alexander and Salmen, Sunnhild and Bernhardt, Günther and Buschauer, Armin and Dove, Stefan (2005) Structure-Based Design Of Bacterial Hyaluronan Lyase Inhibitors,. QSAR & Combinatorial Science 24 (4), pp. 458-469.

Salmen, Sunnhild and Hoechstetter, Julia and Käsbauer, Christian and Paper, Dieter H. and Bernhardt, Günther and Buschauer, Armin (2005) Sulphated Oligosaccharides as Inhibitors of Hyaluronidases from Bovine Testis, Bee Venom and Streptococcus agalactiae. Planta Med. 71, pp. 727-732.

Gust, Ronald and Niebler, Karlheinz and Schönenberger, Helmut (2005) [N-Ethyl- and [N,N'-Diethyl-1,2-bis(2,6-difluoro-3-hydroxyphenyl)ethylenediamine]dichloroplatinum(II): Structure and Cytotoxic/Estrogenic Activity in Breast Cancer Cells. Journal of Medicinal Chemistry 48 (23), pp. 7132-7144.

2004

Wieser, Carsten (2004) Herpesvirus saimiri basierte Vektoren für die somatische Gentherapie der Rheumatoiden Arthritis. PhD, Universität Regensburg

Botzki, Alexander (2004) Structure-based design of hyaluronidase inhibitors. PhD, Universität Regensburg

Kießling, Stephan and Müller-Newen, Gerhard and Leeb, Sandra N. and Hausmann, Martin and Rath, Heiko C. and Strater, Jörn and Spottl, Tanja and Schlottmann, Klaus and Grossmann, Johannes and Montero-Julian, F. A. and Schölmerich, Jürgen and Andus, Tilo and Buschauer, Armin and Heinrich, Peter C. and Rogler, Gerhard (2004) Functional Expression of the Interleukin-11 Receptor α-Chain and Evidence of Antiapoptotic Effects in Human Colonic Epithelial Cells. The Journal of Biological Chemistry 279 (11), pp. 10304-10315.

Salmen, Sunnhild (2004) Inhibitors of bacterial and mammalian hyaluronidase - Synthesis and structure-activity relationships. PhD, Universität Regensburg

Walter, Georg and Liebl, Renate and Angerer, Erwin von (2004) 2-phenylindole sulfamates: inhibitors of steroid sulfatase with antiproliferative activity in MCF-7 breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology 88 (4-5), pp. 409-420.

Bernhardt, Günther and Brunner, Henri and Gruber, Nick and Lottner, Christian and Pushpan, Simi K. and Tsuno, Takashi and Zabel, Manfred (2004) Carboplatin derivatives with superior antitumor activity compared to the parent compound. Inorganica Chimica Acta 357 (15), pp. 4452-4466.

Dittmar, Michael and Kiourkenidis, Georgios and Horn, Markus and Bollwein, Susanne and Bernhardt, Günther (2004) Cerebral ischemia, matrix metalloproteinases, and TNF-alpha: MMP inhibitors may act not exclusively by reducing MMP activity. Stroke 35 (7), e338-e340.

Lottner, Christian and Knuechel, Ruth and Bernhardt, Günther and Brunner, Henri (2004) Combined chemotherapeutic and photodynamic treatment on human bladder cells by hematoporphyrin-platinum(II) conjugates. Cancer letters 203 (2), pp. 171-180.

Gürtler, Ulrich and Fuchs, Peter and Stangelmayer, Achim and Bernhardt, Günther and Buschauer, Armin and Spruss, Thilo (2004) Construction and validation of a microprocessor controlled extracorporal circuit in rats for the optimization of isolated limb perfusion. Archiv der Pharmazie 33 (12), pp. 672-681.

Lottner, Christian and Knuechel, Ruth and Bernhardt, Günther and Brunner, Henri (2004) Distribution and subcellular localization of a water-soluble hematoporphyrin-platinum(II) complex in human bladder cancer cells. Cancer letters 215 (2), pp. 167-177.

Botzki, Alexander and Rigden, Daniel J. and Braun, Stephan and Nukui, Masatoshi and Salmen, Sunnhild and Hoechstetter, Julia and Bernhardt, Günther and Dove, Stefan and Buschauer, Armin and Jedrzejas, Mark J. (2004) L-ascorbic acid-6-hexadecanoate, a potent hyaluronidase inhibitor: X-ray structure and molecular modeling of enzyme-inhibitor complexes. The Journal of Biological Chemistry 279 (44), pp. 45990-45997.

Dove, Stefan (2004) Picolinic Acids as Inhibitors of Dopamine b-Monooxygenase: QSAR and Putative Binding Site. Archiv der Pharmazie 337 (12), pp. 645-653.

Walter, Georg and Liebl, Renate and Angerer, Erwin von (2004) Stilbene-based inhibitors of estrone sulfatase with a dual mode of action in human breast cancer cells. Archiv der Pharmazie 337 (12), pp. 634-644.

Dove, Stefan and Elz, Sigurd and Seifert, Roland and Buschauer, Armin (2004) Structure-Activity Relationships of Histamine H_2 Receptor Ligands,. Mini-Rev. Med. Chem. 4 (9), pp. 941-954.

Brennauer, Albert and Dove, Stefan and Buschauer, Armin (2004) 18. Structure-Activity Relationships of Nonpeptide Neuropeptide Y Receptor Antagonists. In: Michel, M. C., (ed.) Neuropeptide Y and Related Peptides. Handbook of Experimental Pharmacology, 162 (18). Springer, Heidelberg, pp. 505-546. ISBN 978-3-540-40581-8.

Walter, Georg and Liebl, Renate and Angerer, Erwin von (2004) Synthesis and biological evaluation of stilbene-based pure estrogen antagonists. Bioorganic & Medicinal Chemistry Letters 14 (18), pp. 4659-4663.

Schertl, Sabine and Hartmann, Rolf W. and Batzl-Hartmann, Christine and Bernhardt, Günther and Spruß, Thilo and Beckenlehner, Karin and Koch, Marion and Krauser, Rudolf and Schlemmer, Richard and Gust, Ronald and Schönenberger, Helmut (2004) [1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action I: antitumor activity due to the reduction of the endogenous estrogen level. Archiv der Pharmazie 337 (6), pp. 335-348.

Schertl, Sabine and Hartmann, Rolf W. and Batzl-Hartmann, Christine and Bernhardt, Günther and Spruss, Thilo and Beckenlehner, Karin and Koch, Marion and Krauser, Rudolf and Schlemmer, Richard and Gust, Ronald and Schönenberger, Helmut (2004) [1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action II: contribution of drug inactivation, cellular drug uptake and sterical factors in the drug-target interaction to the antitumor activity. Archiv der Pharmazie 337 (6), pp. 349-359.

2003

Hähnel, Viola (2003) Die transkriptionelle Regulation der Toll-like Rezeptoren (TLR2, TLR3 und TLR4) in mononukleären Phagozyten. PhD, Universität Regensburg

Graichen, Florian (2003) Neuropeptid Y Y1-Rezeptorantagonisten der Argininamid-Reihe: Entwicklung von Synthesemethoden an polymeren Trägern und Strategien zur Herstellung von Radioliganden. PhD, Universität Regensburg

Stopfer, Peter (2003) Biologische Wirkungen der Aktivierung des Lymphotoxin-beta-Rezeptors. PhD, Universität Regensburg

Heinz, Sven (2003) Identification and characterization of genes with specific expression in dendritic cells. PhD, Universität Regensburg

Parker, Steven L. and Parker, Michael S. and Buschauer, Armin and Balasubramaniam, Ambikaipakan (2003) Ligand internalization by cloned neuropeptide Y Y5 receptors excludes Y2 and Y4 receptor-selective peptides. European Journal of Pharmacology 474 (1), pp. 31-42.

Li, Liantao and Mayer, Matthias and Schneider, Erich and Schreiber, Elvira and Bernhardt, Günther and Peng, Shiqi and Buschauer, Armin (2003) Preparation of fluorescent nonpeptidic neuropeptide Y receptor ligands: analogues of the quinazoline-type anti-obesity Y5 antagonist CGP 71683A. Arch Pharm (Weinheim) 336 (12), pp. 585-590.

Li, Liantao and Kracht, Julia and Peng, Shiqi and Bernhardt, Günther and Elz, Sigurd and Buschauer, Armin (2003) Synthesis and pharmacological activity of fluorescent histamine H2 receptor antagonists related to potentidine,. Bioorganic & Medicinal Chemistry Letters 13 (10), 0960-894.

Böhmer, F.D. and Karagyozov, L. and Uecker, A. and Serve, H. and Botzki, A. and Mahboobi, Siavosh and Dove, Stefan (2003) A single amino acid exchange inverts susceptibility of related receptor tyrosine kinases for the ATP-site inhibitor STI-571. The Journal of Biological Chemistry 278 (7), pp. 5148-5155.

Oettl, Martin and Hoechstetter, Julia and Asen, Iris and Bernhardt, Günther and Buschauer, Armin (2003) Comparative characterization of bovine testicular hyaluronidase and a hyaluronate lyase from Streptococcus agalactiae in pharmaceutical preparations. European Journal of Pharmaceutical Sciences 18 (3-4), pp. 267-277.

Seifert, Roland and Wenzel-Seifert, Katharina and Bürckstümmer, Tilmann and Pertz, Heinz H. and Schunack, Walter and Dove, Stefan and Buschauer, Armin and Elz, Sigurd (2003) Multiple differences in agonist and antagonist pharmacology between human and guinea pig histamine H1-receptor,. Journal of Pharmacology and Experimental Therapeutics 305, pp. 1104-1115.

Bart, Karl-Christian and Bernhardt, Günther and Brunner, Henri and Lottner, Christian (2003) Preparation of novel, water-soluble porphyrin platinum amine compounds with high tumor selectivity and their use for the treatment of benign and malignant tumor diseases.

Li, Liantao and Kracht, Julia and Peng, Shiqi and Bernhardt, Günther and Buschauer, Armin (2003) Synthesis and pharmacological activity of fluorescent histamine H1 receptor antagonists related to mepyramine,. Bioorganic & Medicinal Chemistry Letters 13 (7), pp. 1245-1248.

Klein, Michael and Zabel, Manfred and Bernhardt, Günther and König, Burkhard (2003) Tetrahydroxy 10-membered cyclic enediynes. The Journal of organic chemistry 68 (24), pp. 9379-9383.

Radons, Jürgen and Dove, Stefan and Neumann, D. and Altmann, R. and Botzki, Alexander and Martin, M.U. and Falk, Werner (2003) The IL-1 receptor accessory protein TIR domain: analysis of putative interaction sites by in-vitro mutagenesis and molecular modeling. The Journal of Biological Chemistry 278 (49), pp. 49145-49153.

2002

Mayer, Matthias (2002) Entwicklung fluorimetrischer Methoden zur Bestimmung der Affinität und Aktivität von Liganden G-Protein-gekoppelter Rezeptoren an intakten Zellen. PhD, Universität Regensburg

Kießling, Stephan (2002) Funktionelle Untersuchungen zur Expression des Interleukin-11 Rezeptors alpha in humanen Kolonepithelzellen. PhD, Universität Regensburg

Parker, S.L. and Parker, M. S. and Lundell, I. and Balasubramaniam, A. and Buschauer, Armin and Kane, J. K. and Yalcin, A. and Berglund, M. M. (2002) Agonist internalization by cloned Y1 neuropeptide Y (NPY) receptor in Chinese hamster ovary cells shows strong preference for NPY, endosome-linked entry and fast receptor recycling. Regulatory Peptides 107 (1-3), pp. 49-62.

Mahboobi, Siavosh and Teller, S. and Pongratz, H. and Hufsky, H. and Sellmer, A. and Botzki, Alexander and Uecker, A. and Beckers, T. and Baasner, S. and Schächtele, C. and Überall, F. and Kassack, M. U. and Dove, Stefan and Böhmer, F.-D. (2002) Bis(1H-2-indolyl)methanones as a novel class of inhibitors of the platelet-derived growth factor receptor kinase. Journal of Medicinal Chemistry 45 (5), pp. 1002-1018.

Vogelhuber, Werner and Spruß, Thilo and Bernhardt, Günther and Buschauer, Armin and Göpferich, Achim (2002) Efficacy of BCNU and paclitaxel loaded subcutaneous implants in the interstitial chemotherapy of U-87 MG human glioblastoma xenografts,. International Journal of Pharmaceutics 238 (1-2), pp. 111-121.

Bernhardt, Günther and Beckenlehner, Karin and Spruss, Thilo and Schlemmer, Richard and Reile, Herta and Schönenberger, Helmut (2002) Establishment and Characterization of New Murine Breast Cancer Cell Lines. Archiv der Pharmazie 335 (2), pp. 55-68.

Bernhardt, Günther and Beckenlehner, Karin and Spruss, Thilo and Schlemmer, Richard and Reile, Herta and Schönenberger, Helmut (2002) Establishment and characterization of new murine breast cancer cell lines. Archiv der Pharmazie 335 (2-3), pp. 55-68.

Lottner, Christian and Bart, Karl-Christian and Bernhardt, Günther and Brunner, Henri (2002) Hematoporphyrin-derived soluble porphyrin-platinum conjugates with combined cytotoxic and phototoxic antitumor activity. Journal of medicinal chemistry 45 (10), pp. 2064-2078.

Weiss, Thomas S. and Bernhardt, Günther and Buschauer, Armin and Thasler, Wolfgang E. and Dolgner, Doris and Zirngibl, Hubert and Jauch, Karl-Walter (2002) Polyamine levels of human colorectal adenocarcinomas are correlate with tumor stage and grade,. International Journal of Colorectal Disease 17 (6), pp. 381-387.

Lottner, Christian and Bart, Karl-Christian and Bernhardt, Günther and Brunner, Henri (2002) Soluble tetraarylporphyrin-platinum conjugates as cytotoxic and phototoxic antitumor agents. Journal of medicinal chemistry 45 (10), pp. 2079-2089.

Golob, Thomas and Liebl, Renate and Angerer, Erwin von (2002) Sulfamoyloxy-substituted 2-phenylindoles: antiestrogen-based inhibitors of the steroid sulfatase in human breast cancer cells. Bioorganic & Medicinal Chemistry 10 (12), pp. 3941-3953.

Bouchal, Jan and Kolár, Zdenek and Mad'arová, Jana and Hlobilková, Alice and Angerer, Erwin von (2002) The effects of natural ligands of hormone receptors and their antagonists on telomerase activity in the androgen sensitive prostatic cancer cell line LNCaP. Biochemical Pharmacology 63 (6), pp. 1177-81.

Fellner, Stephan and Bauer, Björn and Miller, David S. and Schaffrick, Martina and Fankhänel, Martina and Spruß, Thilo and Bernhardt, Günther and Graeff, Claudia and Färber, Lothar and Gschaidmeier, Harald and Buschauer, Armin and Fricker, Gert (2002) Transport of paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivo. The Journal of Clinical Investigation 110 (9), pp. 1309-1318.

2001

Schertl, Sabine and Hartmann, Rolf W. and Batzl-Hartmann, Christine and Schlemmer, Richard and Spruß, Thilo and Bernhardt, Günther and Gust, Ronald and Schönenberger, Helmut (2001) 1-(2,6-dichloro-4-hydroxyphenyl)-2-phenylethanes--new biological response modifiers for the therapy of breast cancer. Synthesis and evaluation of estrogenic/antiestrogenic properties. Archiv der Pharmazie 334 (4), pp. 125-137.

Dove, Stefan (2001) Alignment of molecules by weighted field fit considering active shape. In: Höltje, H.-D. and Sippl, W., (eds.) Rational Approaches to Drug Design - 13th European Symposium on QSAR. J. R. Prous Science, S. A., Barcelona, Philadelphia, 316 - 322.

Dove, Stefan (2001) Arzneistoffe aus dem Computer – Modellierung molekularer Schlüssel für biologische Schlösser. Blick in die Wissenschaft (Forschungsmagazin Univ. Regensburg) 13, pp. 22-26.

Schuster, Andreas and Götte, Carsten and Bernhardt, Günther and Buschauer, Armin (2001) Chiral separation of pheniramine-like 3-phenyl-3-heteroarylpropylamines by CE and HPLC methods,. Chirality 13 (6), pp. 285-293.

Kelley, Melissa T. and Bürckstümmer, Tilmann and Wenzel-Seifert, Katharina and Dove, Stefan and Buschauer, Armin and Seifert, Roland (2001) Distinct interaction of human and guinea pig histamine H_2-Receptor with guanidine-type agonists,. Molecular Pharmacology 60 (6), pp. 1210-1225.

Schlemmer, Richard and Spruß, Thilo and Bernhardt, Günther and Schönenberger, Helmut (2001) Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] dichloroplatinum(II) act as an immune response modifier? IV. Inhibition of the proliferation-increasing effect of progressively growing MXT-M-3,2 breast cancer on phagocytes by the title compound. Archiv der Pharmazie 334 (10), pp. 309-317.

Bischoff, Andrea and Püttmann, Kristina and Kötting, Annette and Moser, Christiane and Buschauer, Armin and Michel, Martin C. (2001) Limited signal transduction repertoire of human Y_5 neuropeptide Y receptors expressed in HEC-B cells. Peptides 22 (3), pp. 387-394.

Vogelhuber, W. and Rutunno, P. and Magni, E. and Gazzaniga, A. and Spruss, Thilo and Bernhardt, Günther and Buschauer, Armin and Goepferich, Achim (2001) Programmable biodegradable implants. Journal of Controlled Release 73 (1), pp. 75-88.

Wenzel-Seifert, Katharina and Kelley, Melissa T. and Buschauer, Armin and Seifert, Roland (2001) Similar apparent constitutive activity of human histamine H_2-receptor fused to long and short splice variants of Gsa,. Journal of Pharmacology and Experimental Therapeutics 299 (3), pp. 1013-1020.

Meiers, S. and Kemény, M. and Weyand, U. and Gastpar, R. and Angerer, E. von and Marko, D. (2001) The anthocyanidins cyanidin and delphinidin are potent inhibitors of the epidermal growth-factor receptor. Journal of Agricultural and Food Chemistry 49 (2), pp. 958-962.

2000

Zabel, Manfred and Breu, Josef and Rau, Franz and Range, Klaus-Jürgen and Krey, Volker and Uffrecht, Anka and Buschauer, Armin (2000) Absolute configuration of (-)-4-(3,4-dichlorophenyl)-4-(2-pyridyl)butanoic acid: essential information to determine crucial steric feature of arpromidine-type histamine H_2 receptor agonists. Acta Crystallographica Section C 56, pp. 250-251.

Golob, T. and Biberger, C. and Walter, G. and Angerer, E. von (2000) Antiestrogenic activities of 3,8-dihydroxy-6,11-dihydrobenzo[a]carbazoles with sulfur-containing side chains. Archiv der Pharmazie 333 (9), pp. 305-311.

Moser, Christiane and Bernhardt, Günther and Michel, J. and Schwarz, H. and Buschauer, Armin (2000) Cloning and functional expression of the hNPY Y_5 receptor in human endometrial cancer (HEC-1B) cells. Can J. Physiol. Pharmacol 78, pp. 134-142.

Schlemmer, Richard and Spruß, Thilo and Bernhardt, Günther and Schönenberger, Helmut (2000) Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloro-platinum(II) act as an immune response modifier? Part III: Progressively growing MXT-M-3,2 breast cancer stimulates the proliferation of phagocytes in B6D2F1 mice. Archiv der Pharmazie 333 (12), pp. 404-414.

Schlemmer, Richard and Spruß, Thilo and Bernhardt, Günther and Schönenberger, Helmut (2000) Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloroplatinum(II) act on the hormone-sensitive, murine breast cancer as a biological response modifier? Part 1: The MXT-M-3.2 breast cancer stimulates the growth of an identical second graft; [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]dichloroplat inum (II) inhibits this process. Archiv der Pharmazie 333 (2-3), pp. 69-71.

Schlemmer, Richard and Spruß, Thilo and Bernhardt, Günther and Schönenberger, Helmut (2000) Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloroplatinum(II) act on the hormone-sensitive, murine breast cancer as a biological response modifier? Part II. Studies on the influence of [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] dichloroplatinum(II) on the specific immune defense in MXT-M-3,2 breast cancer bearing mice. Archiv der Pharmazie 333 (12), pp. 397-403.

Buschauer, Armin and Bernhardt, Günther and Dove, Stefan (2000) NPY-Rezeptoren als Zielstrukturen für neue Arzneistoffe. Pharmazeutische Zeitung 24, pp. 11-18.

Dove, Stefan and Michel, Martin C. and Knieps, Sebastian and Buschauer, Armin (2000) Pharmacology and quantitative structure-activity relationships of imidazolylpropylguanidines with mepyramine-like substructures as non-peptide neuropeptide Y Y_1 receptor antagonists,. Can. J. Physiol. Pharmacol 78, pp. 108-115.

Aiglstorfer, Iris and Hendrich, Ingo and Moser, Christiane and Bernhardt, Günther and Dove, Stefan and Buschauer, Armin (2000) Structure-Activity Relationships of Neuropeptide Y Y_1 Receptor Antagonists Related to BIBP 3226,. Bioorganic & Medicinal Chemistry Letters 10 (14), pp. 1597-1600.

Gust, Ronald and Faderl, Michael and Schönenberger, Helmut (2000) [Aqua-1-(2,6-dichloro-4-hydroxyphenyl)-2-phenylethylenediamine] sulfatoplatinum(II) complexes with variable substituents in the 2-phenyl ring 3. Investigation of breast cancer inhibiting properties. Journal of cancer research and clinical oncology 126 (11), pp. 647-654.

1999

Meister, A. and Bernhardt, Günther and Christoffel, V. and Buschauer, Armin (1999) Antispasmodic Activity of Thymus vulgaris, Extract on the Isolated Guinea-Pig Trachea: Discrimination Between Drug and Ethanol Effects. Planta Med 1999, pp. 512-516.

Moser, Christiane and Bernhardt, Günther and Buschauer, Armin (1999) Efficient Transfection of Human Endometrial Cancer (HEC-1B) Cells with FuGENE^TM 6 Transfection Reagent. biochemica 1/1999, pp. 26-27.

Mahboobi, Siavosh and Dove, Stefan and Kuhr, S. and Popp, A. (1999) Homo-arcyriaflavin: The synthesis of ring-expanded arcyriaflavin analogs. The Journal of Organic Chemistry 64 (22), pp. 8130-8137.

Dove, Stefan and Buschauer, Armin (1999) Improved Alignment by Weighted Field Fit in CoMFA of Histamine H_2 Receptor Agonistic Imidazolylpropylguanidines. Quant. Struct.-Act. Relat. 18 (4), pp. 329-341.

Mahboobi, Siavosh and Dove, Stefan and Kuhr, S. and Pongratz, Hewig (1999) Synthesis of arcyriarubine regioisomers by Pd(0)-catalysis or via lithiated indole derivatives - conformational analysis by semiempirical and X-ray methods. Pharmazie 54 (11), pp. 820-827.

Gust, Ronald and Heinrich, Heike and Krauser, Rudolf and Schönenberger, Helmut (1999) [Meso- and rac-1,2-bis(4-fluorophenyl)ethylenediamine]chloro[sulfinylbis(methane)-S]platinum(II) chloride new water soluble platinum complexes with high anti-breast cancer activities. Inorganica chimica acta 285 (2), pp. 184-189.

Schlemmer, Richard and Spruß, Thilo and Bernhardt, Günther and Schönenberger, Helmut (1999) [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl) ethylenediamine]dichloroplatinum(II), a compound with a specific activity on hormone-sensitive breast cancers--evidence for a diethylstilbestrol-like mode of action. Archiv der Pharmazie 332 (2), pp. 59-69.

Bernhardt, Günther and Koch, Marion and Spruss, Thilo and Gust, Ronald and Krauser, Rudolf and Schlemmer, Richard and Hollstein, Michael and Lux, Franz and Schönenberger, Helmut (1999) [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] sulfatoplatinum(II)--pharmacokinetic studies. Archiv der Pharmazie 332 (6), pp. 195-200.

1998

Biberger, C. and Angerer, E. von (1998) 1-Benzyl-2-phenylindole- and 1,2-diphenylindole-based antiestrogens. Estimation of agonist and antagonist activities in transfection assays. The Journal of Steroid Biochemistry and Molecular Biology 64 (5-6), pp. 277-285.

Leichtl, S. and Angerer, E. von (1998) 2-Phenylbenzo[b]thiophene-based antiestrogens with mammary tumor inhibiting activity. Archiv der Pharmazie 331 (9), pp. 283-289.

Schuster, Andreas and Bernhardt, Günther and Eibler, Ernst and Buschauer, Armin and Hesselink, Willy (1998) Chiral separation of 3-phenyl-3-(2-pyridyl)propylamines, and analogous guanidines and guanidine-N-carboxylic acid esters with HPLC and CZE. Journal of Chromatography A 793 (1), pp. 77-90.

Schulze, Frank R. and Buschauer, Armin and Schunack, Walter (1998) Combined histamine H_1/H_2 receptor antagonists: Part I. Pharmacological hybrids with pheniramine- and roxatidine-like substructures ,. European Journal of Pharmaceutical Sciences 6, pp. 177-186.

Wolf, Cornelia and Schulze, Frank R. and Buschauer, Armin and Schunack, Walter (1998) Combined histamine H_1/H_2 receptor antagonists: Part II. Pharmacological hybrids with pheniramine- and tiotidine-like substructures,. European Journal of Pharmaceutical Sciences 6 (3), pp. 187-196.

Dove, Stefan (1998) Computermethoden im Arzneimitteldesign. In: Lehner, L. and Braungart, G. and Hitzenberger, L., (eds.) Multimedia in Lehre und Forschung. Gabler Edition Wissenschaft. Gabler Verlag, Deutscher Universitäts-Verlag, Wiesbaden, 75 - 88. ISBN 3-8244-6602-3.

Mayer, Klaus K. and Dove, Stefan and Pongratz, Herwig and Ertan, M. and Wiegrebe, Wolfgang (1998) Electron impact induced fragmentation of 4-aryl-4,6,7,8-tetrahydro-1H,3H-quinazolinone-2,5-diones. Heterocycles 48 (6), pp. 1169-1183.

Pillwein, Konrad and Fuiko, R. and Slavc, I. and Czech, T. and Hawliczek, G. and Bernhardt, Günther and Nirnberger, Gunther and Koller, U. (1998) Hyaluronidase additional to standard chemotherapy improves outcome for children with malignant brain tumors. Cancer Letters (Shannon, Ireland) 131 (1), pp. 101-108.

Dove, Stefan and Buschauer, Armin (1998) Imidazolylpropylguanidines as histamine H_2 receptor agonists: 3D-QSAR of a large series. Pharm. Acta Helv. 73 (3), pp. 145-155.

Gastpar, R. and Goldbrunner, M. and Marko, D. and Angerer, E. von (1998) Methoxy-substituted 3-formyl-2-phenylindoles inhibit tubulin polymerization. Journal of Medicinal Chemistry 41 (25), pp. 4965-4972.

Aiglstorfer, Iris and Uffrecht, Anka and Geßele, K. and Moser, Christiane and Schuster, Andreas and Merz, S. and Malawska, B. and Bernhardt, Günther and Dove, Stefan and Buschauer, Armin (1998) NPY Y_1 antagonists: structure-activity relationships of arginine derivatives and hybrid compounds with arpromidine-like partial structures. Regul. Pept. 75, pp. 75-76.

Muckenschnabel, I. and Bernhardt, Günther and Spruß, Thilo and Buschauer, Armin (1998) Pharmacokinetics and tissue distribution of bovine testicular hyaluronidase and vinblastine in mice: an attempt to optimize the mode of adjuvant hyaluronidase administration in cancer chemotherapy. Cancer Letters 131 (1), pp. 71-84.

Muckenschnabel, Ingo and Bernhardt, Günther and Spruß, Thilo and Dietl, Barbara and Buschauer, Armin (1998) Quantitation of hyaluronidases by the Morgan-Elson reaction: comparison of the enzyme activities in the plasma of tumor patients and healthy volunteers. Cancer Letters 131, pp. 13-20.

Gust, Ronald and Schnurr, Beate and Krauser, Rudolf and Bernhardt, Günther and Koch, Marion and Schmid, Beate and Hummel, Evelyn and Schönenberger, Helmut (1998) Stability and cellular studies of [rac-1,2-bis(4-fluorophenyl)ethylenediamine][cyclobutane-1,1-dicarboxylato]platinum(II), a novel, highly active carboplatin derivative. Journal of Cancer Research and Clinical Oncology 124 (11), pp. 585-597.

Schuster, Andreas and Bollwein, Susanne and Uffrecht, Anka and Krey, Volker and Götte, Carsten and Bernhardt, Günther and Buschauer, Armin (1998) Stereochemical Investigations on Intermediates for the Synthesis of Histamine H_2 Receptor Agonists and Neuropeptide Y Y_1 Antagonists: Chiral Separation of Phenyl(pyridyl)alkanoic Acids by HPLC and CE. Sci. Pharm 66, pp. 263-278.

Gust, Ronald and Krauser, Rudolf and Schmid, Beate and Schönenberger, Helmut (1998) Synthesis and antitumor activity of [1,2-bis(4-fluorophenyl)ethylenediamine][dicarboxylato]platinum(II) complexes. Archiv der Pharmazie 331 (1), pp. 27-35.

1997

Muckenschnabel, I. and Bernhardt, Günther and Spruß, Thilo and Buschauer, Armin (1997) A versatile HPLC method for the measurement of melphalan tailored to the optimization of hyperthermic isolated limb perfusion,. Eur. J. Pharm. Sci. 5, pp. 129-137.

Märkl, Gottfried and Stiegler, J. and Kreitmeier, Peter and Burgemeister, Thomas and Kastner, F. and Dove, Stefan (1997) Configurational and conformational isomeric antiaromatic [28]tetraoxaporphyrinoids(4.2.4.2) and aromatic [26]tetraoxaporphyrin(4.2.4.2) dications. A new type of molecular dynamics in macrocyclic systems. Helvetica Chimica Acta 80 (1), pp. 14-42.

Schuster, Andreas and Bernhardt, Günther and Buschauer, Armin (1997) Determination of the arpromidine-type histamine H2-receptor agonist N1-[3-(3,4-difluoro­phe­nyl)-3-(2-pyridyl)propyl]-N2-[3-(1H-imidazol-4-yl)propyl]guanidine and corresponding N3-alkoxycarbonylguanidines by HPLC and CE. Eur. J. Pharm. Sci. 5, pp. 79-88.

Weiss, Thomas and Bernhardt, Günther and Buschauer, Armin and Jauch, Karl-Walter and Zirngibl, Hubert (1997) High-resolution RP HPLC analysis of polyamines and their monoacetyl conjugates by fluorescence detection after derivatization with N-hydroxy-succinimidyl 6-quinolinyl carbamate. Anal. Biochem 247, pp. 294-304.

Goldbrunner, M. and Loidl, G. and Polossek, T. and Mannschreck, A. and Angerer, E. von (1997) Inhibition of tubulin polymerization by 5,6-dihydroindolo[2,1-alpha]isoquinoline derivatives. Journal of Medicinal Chemistry 40 (22), pp. 3524-3533.

Buschauer, Armin (1997) Pharmakotherapie der Tuberkulose: Wirkmechanismen und Resistenzen,. Pharm. Ztg. 142, pp. 209-223.

Dove, Stefan and Buschauer, Armin (1997) Stepwise leave-one-isomer-out Free-Wilson approaches as preprocessing tools in QSAR analysis of racemates. Quant. Struct.-Act. Relat. 16, pp. 11-19.

Müller, Manfred and Knieps, Sebastian and Geßele, Karin and Dove, Stefan and Bernhardt, Günther and Buschauer, Armin (1997) Synthesis and neuropeptide Y Y1 receptor antagonistic activity of N,N-disubstituted w -guanidino- and w -aminoalkanoic acid amides. Arch. Pharm. - Pharm. Med. Chem. (Weinheim) 330, pp. 333-342.

Gust, Ronald and Gelbcke, Michael and Angermaier, Bernhard and Bachmann, Helmut and Krauser, Rudolf and Schönenberger, Helmut (1997) The stereoselectivity of antitumor active [1,2-diamino-1-phenylpropane]dichloroplatinum(II) complexes. Inorganica chimica acta 264 (1-2), pp. 145-160.

Mahboobi, Siavosh and Dove, Stefan and Bednarski, P. J. and Kuhr, S. and Burgemeister, Thomas and Schollmeyer, D. (1997) X-Ray Crystal Structure of Woodinine and Conformational Analysis by Means of Semiempirical and 1H-NMR Methods. Journal of Natural Products-Copublished with the Am. Soc. of Pharmacognosy 60 (6), pp. 587-591.

1996

Biberger, C. and Angerer, E. von (1996) 2-Phenylindoles with sulfur containing side chains. Estrogen receptor affinity, antiestrogenic potency, and antitumor activity. The Journal of Steroid Biochemistry and Molecular Biology 58 (1), pp. 31-43.

Gust, Ronald and Krauser, Rudolf and Schmid, Beate and Schönenberger, Helmut (1996) Breast cancer inhibiting diastereomeric diacetato[1,2-bis(4-fluorophenyl)ethylenediamine]platinum(II) derivatives: synthesis and studies on the relationship between reactivity and antitumor activity. Inorganica chimica acta 250 (1-2), pp. 203-218.

Spruss, Thilo and Bernhardt, Günther (1996) Chemosensitivity of malignant melanoma models: long-term complete remission after regional hyaluronidase/vinblastine therapy. In: Arnold, Wolfgang, (ed.) Immunodeficient Animals: Models for Cancer Research. Contributions to Oncology, 51. UNSPECIFIED, pp. 145-150.

Lux, Franz and Hollstein, Michael and Reile, Herta and Bernhardt, Günther and Schönenberger, Helmut (1996) Discrepancy between cytotoxicity, platinum accumulation, and DNA platination in MCF-7 breast cancer cells treated with diaqua(1,2-diphenylethylenediamine) platinum(II) sulfates and cisplatin. Biological Trace Element Research 53 (1-3), pp. 113-128.

Hafner, F. and Holler, E. and Angerer, E. von (1996) Effect of growth factors on estrogen receptor mediated gene expression. The Journal of Steroid Biochemistry and Molecular Biology 58 (4), pp. 385-393.

Angerer, Erwin von (1996) Entwicklungsstrategien fur Arzneistoffe zur Therapie hormonabhangiger Tumoren. Pharmazie in unserer Zeit 25 (2), pp. 74-84.

Muckenschnabel, Ingo and Bernhardt, Günther and Spruß, Thilo and Buschauer, Armin (1996) Hyaluronidase pretreatment produces selective melphalan enrichment in malignant melanoma implanted in nude mice. Cancer Chemother. Pharmacol 38, pp. 88-94.

Knieps, Sebastian and Dove, Stefan and Michel, Martin C. and Rottmeier, Karin and Wernet, W. and Bernhardt, Günther and Buschauer, Armin (1996) w -Phenyl-w -(2-pyridyl)alkyl-substituted bisguanidines are moderate neuropeptide Y antagonists. Pharm. Pharmacol. Lett. 6, pp. 27-30.

1995

Mokrosz, M.J. and Strekowski, L. and Kosak, W.X. and Duszynska, B. and Bojarski, A.J. and Klodzinska, A. and Czarny, A. and Cegla, M.T. and Deren-Wesolek, A. and Chojnacka-Wojcik, E. and Dove, Stefan and Mokrosz, J.L. (1995) 4,6-Di(heteroaryl)-2-(N-methylpiperazino)pyrimidines as New, Potent 5-HT2A Receptor Ligands: A Verification of the Topographic Model. Archiv der Pharmazie 328 (9), pp. 659-666.

Glaß, D. and Buschauer, Armin and Tenor, H. and Bartel, S. and Will-Shahab, L. and Krause, E.-G. (1995) 4-(4-Guanidinobenzoyl)-2-imidazolones and related compounds: Phosphodiesterase inhibitors and novel cardiotonics with combined histamine H2 receptor agonist and PDE III inhibitor activity. Arch. Pharm. (Weinheim) 328, pp. 709-719.

Hagelüken, Astrid and Burde, Rahel and Nürnberg, Bern and Harhammer, R. and Buschauer, Armin and Seifert, Roland (1995) Cationic-amphiphilic arpromidine-derived guanidines and a histamine trifluoromethyl-toluidide derivative may activate pertussis toxin-sensitive G-proteins by a receptor-independent mechanism. Naunyn Schmiedeberg's Arch. Pharmacol. 351, pp. 305-308.

Gust, Ronald and Bernhardt, Günther and Spruss, Thilo and Krauser, Rudolf and Koch, Marion and Schönenberger, Helmut and Bauer, Kurt H. and Schertl, Sabine and Lu, Zhi (1995) Development of a parenterally administrable hydrosol preparation of the "third generation platinum complex" [(+/-)-1,2-bis(4-fluorophenyl)ethylenediamine]dichloroplatinum(II). Part 1. Preparation and studies on the stability and antitumor activity. Archiv der Pharmazie 328 (9), pp. 645-653.

Gust, Ronald and Bernhardt, Günther and Spruss, Thilo and Krauser, Rudolf and Koch, Marion and Schönenberger, Helmut and Bauer, Kurt-Heinz and Schertl, Sabine and Lu, Zhi (1995) Development of a parenterally administrable hydrosol preparation of the \"third generation platinum complex\" [(+-)-1,2-bis(4-fluorophenyl)ethylenediamine]dichloroplatinum(II). Part 1. Preparation and studies on the stability and antitumor activity. Archiv der Pharmazie (Weinheim, Germany) 328 (9), pp. 645-653.

Coruzzi, Gabriela and Adami, Maristella and Pozzoli, Cristina and Buschauer, Armin and Bertaccini, Giulio (1995) Different activities of impromidine and related phenyl-(pyridylalkyl)guanidines at cardiac and gastric H_2 receptors. Inflamm. Res. 44 (Supl. 1), pp. 108-109.

Dove, Stefan and Kühne, R. and Schunack, W. (1995) H1 agonistic 2-heteroaryl and 2-phenylhistamines: CoMFA and possible receptor binding sites. In: Sanz, F. and Giraldo, J. and Manaut, F., (eds.) QSAR and Molecular Modelling: Concepts, Computational Tools and Biological Applications. J. R. Prous Science Publ., Barcelona, 427 - 432.

Felix, Stefan B. and Buschauer, Armin and Baumann, Gert (1995) Haemodynamic profile of new H_2-receptor agonists in congestive heart failure. European Journal Of Clinical Investigation 25 (Suppl. 1), pp. 42-46.

Spruß, Thilo and Bernhardt, Günther and Schönenberger, Helmut and Schiess, Wilfried (1995) Hyaluronidase significantly enhances the efficacy of regional vinblastine chemotherapy of malignant melanoma. Journal of cancer research and clinical oncology 121 (4), pp. 193-202.

Knieps, Sebastian and Michel, Martin C. and Dove, Stefan and Buschauer, Armin (1995) Non-peptide neuropeptide Y antagonists derived from the histamine H_2 agonist arpromidine: Role of the guanidine group. Bioorg. Med. Chem. Lett. 5, pp. 2065-2070.

Angerer, E. von and Biberger, C. and Leichtl, S. (1995) Studies on heterocycle-based pure estrogen antagonists. Annals of the New York Academy of Sciences 761, pp. 176-191.

Buschauer, Armin and Mohr, Rainer and Schunack, Walter (1995) Synthesis and histamine H_2-receptor antagonist activity of 4-(1-pyrazolyl)butanamides, guanidinopyrazoles, and related compounds. Arch. Pharm. (Weinheim) 328, pp. 349-358.

Gust, Ronald and Schönenberger, Helmut (1995) Third generation antitumor platinum(II) complexes of the [1-(fluoro/difluorophenyl)-2-phenylethylenediamine]platinum(II) type. Archiv der Pharmazie 328 (7-8), pp. 595-603.

1994

Angerer, E. von and Biberger, C. and Holler, E. and Koop, R. and Leichtl, S. (1994) 1-Carbamoylalkyl-2-phenylindoles: relationship between side chain structure and estrogen antagonism. The Journal of Steroid Biochemistry and Molecular Biology 49 (1), pp. 51-62.

Mahboobi, Siavosh and Grothus, Götz and von Angerer, Erwin (1994) 3-Substituierte 2-Phenylindole: Synthese und biologische Eigenschaften. Archiv der Pharmazie 327 (8), pp. 481-492.

Meyer, T. and Koop, R. and Angerer, E. von and Schönenberger, H. and Holler, E. (1994) A rapid luciferase transfection assay for transcription activation effects and stability control of estrogenic drugs in cell cultures. Journal of Cancer Research and Clinical Oncology 120 (6), pp. 359-364.

Maucher, A. and Angerer, E. von (1994) Antitumour activity of coumarin and 7-hydroxycoumarin against 7,12-dimethylbenz[a]anthracene-induced rat mammary carcinomas. Journal of cancer research and clinical oncology 120 (8), pp. 502-504.

Angerer, E. von and Kager, M. and Maucher, A. (1994) Antitumour activity of coumarin in prostate and mammary cancer models. Journal of Cancer Research and Clinical Oncology 120 Suppl, S14-S16.

Rixen, D. and Neugebauer, E. and Lechleuthner, A. and Buschauer, Armin and Nagelschmidt, M. and Thoma, S. and Rink, A. (1994) Beneficial effect of H_2-agonism and H_1-antagonism in rat endotoxic shock ? Shock 2, pp. 47-52.

Angerer, S. von and Seidl, E. and Mannschreck, A. and Angerer, E. von and Wiegrebe, Wolfgang (1994) Dibenzo[a,f]quinolizines: syntheses and cytostatic activity in estrogen-sensitive tumor cells. Anti-cancer drug design 9 (1), pp. 25-40.

Horn, D. W. and Vollmer, G. and Angerer, E. von and Schneider, M. R. (1994) Effect of the nonsteroidal antiestrogen ZK 119.010 on growth and metastasis of the EnDA endometrial carcinoma. International journal of cancer. Journal international du cancer 58 (3), pp. 426-429.

Beck, E. and Hofmann, M. and Bernhardt, Günther and Jäger, W. and Wildt, L. and Lang, N. (1994) In vitro activity of immunoconjugates between cisplatin and an anti-CA125 monoclonal antibody on ovarian cancer cell lines. Cell biophysics 24-25, pp. 163-173.

Kleine-Tebbe, Jörg and Josties, C. and Frank, G. and Stalleicken, D. and Buschauer, Armin and Schunack, Walter (1994) Inhibition of IgE- and non-IgE-mediated histamine release from human basophil leukocytes in vitro by a histamine H_1-antagonist, desethoxycarbonyl-loratadine. J. Allergy Clin. Immunol. 93, pp. 494-500.

Baumann, Gert and Buschauer, Armin and Felix, Stefan B. (1994) Mögliche therapeutische Bedeutung sarkolemmaler Histamin-H_2-Rezeptoren bei Herzinsuffizienz: Hämodynamische Effekte neuer H_2-Agonisten. In: Greiling, H., (ed.) Pathobiochemie, Molekularbiologie und moderne Diagnostik kardiovaskulärer Erkrankungen. Springer, Berlin Heidelberg, pp. 104-115.

Franke, R. and Dove, Stefan and Gruska, A. (1994) Physicochemical properties and drug action: alternative QSAR methods. In: Kouronnakis, P. N. and Rekka, E., (eds.) Advanced Drug Design and Development, a Medicinal Chemistry Approach. Ellis Horwood Series in Pharmaceutical Technology. Ellis Horwood, London, 43 - 97. ISBN 0-13-336793-2.

Schulze, Frank R. and Alisch, Rudi A. and Buschauer, Armin and Schunack, Walter (1994) Synthese und kombinierte H_1-/H_2-antagonistische Aktivität von Mepyramin- Pheniramin- und Cyclizin-Derivaten mit Cyanoguanidin-, Harnstoff- und Nitroethendiamin-Partialstrukturen. Arch. Pharm. (Weinheim) 327, pp. 455-462.

Maucher, A. and Angerer, E. von and Hampl, R. and Stárka, L. (1994) The activity of epitestosterone in hormone dependent prostate tumour models. Endocrine regulations 28 (1), pp. 23-29.

1993

Maucher, A. and Angerer, E. von (1993) Antiproliferative activity of casodex (ICI 176.334) in hormone-dependent tumours. Journal of cancer research and clinical oncology 119 (11), pp. 669-674.

Spruß, Thilo and Bernhardt, Günther and Schönenberger, Helmut and Engel, Jürgen (1993) Antitumour activity of miltefosine alone and after combination with platinum complexes on MXT mouse mammary carcinoma models. Journal of cancer research and clinical oncology 119 (3), pp. 142-149.

Dove, Stefan and Schönenberger, Helmut (1993) Computer modelling of estrogenic transcriptional activation can account for different types of dose-response curves of estrogens. The Journal of Steroid Biochemistry and Molecular Biology 46 (2), pp. 163-176.

Kritzenberger, J and Bernhardt, Günther and Gust, Ronald and Pistor, Petra and Schönenberger, Helmut and Yersin, Hartmut. (1993) Dichlorobis(cycloalkylamine)platinum(II) complexes. Structure activity relationship on the human MDA-MB-231 breast cancer cell line. Monatshefte fuer Chemie 124 (5), pp. 587-604.

Buschauer, Armin (1993) Diuretika - eine chemisch-pharmakologische Betrachtung. Pharm. Ztg. 138, pp. 177-188.

Stinner, B. and Hasse, C. and Lorenz, Wilfried and Alisch, Rudi and Schulze, Frank and Sitter, H. and Lüdke, U. and Buschauer, Armin and Schunack, Walter (1993) Effects of drugs combining H_1 and H_2 receptor antagonist activity on histamine release and life threatening anaphylactoid reactions in pigs. Agents Actions 38, Special Conference Issue, C286-C288.

Bernhardt, Günther (1993) Entwicklung und Anwendung moderner Testverfahren zur Auffindung und Optimierung der Antitumorwirkung neuartiger Diphenylethylendiaminplatin(II)-Komplexe. Habilitation, Regensburg, Universität.

Dove, Stefan and Schönenberger, Helmut (1993) Estrogenic activity: An example of considering effectuation models in biological data interpretation and QSAR. In: Wermuth, C. G., (ed.) Trends in QSAR and Molecular Modelling. ESCOM, Leiden, 554 - 555. ISBN 978-90-72199-13-3.

Maucher, A. and Kager, M. and Angerer, E. von (1993) Evaluation of the antitumour activity of coumarin in prostate cancer models. Journal of cancer research and clinical oncology 119 (3), pp. 150-154.

Franke, Rainer and Buschauer, Armin (1993) Interaction terms in Free-Wilson analysis: A QSAR of histamine H_2-agonists. In: Wermuth, C. G., (ed.) Trends in QSAR and Molecular Modelling 92. Escom, Leiden, pp. 160-162.

Hollstein, Michael and Lux, Franz and Reile, Herta and Bernhardt, Günther and Schönenberger, Helmut (1993) NAA of platinated DNA after treatment of cancer cells with new platinum complexes. .

Angerer, Erwin von (1993) Platinum complexes with specific activity against hormone-dependent tumors. In: Keppler, Bernhard K., (ed.) Metal complexes in cancer chemotherapy. VHC, Weinheim, pp. 73-83. ISBN 1-560-81216-8; 3-527-28425-7.

Meyer, Thomas and Goehl, Jonas and Hohenberger, Werner and Christl, Claudia and Bernhardt, Günther and Spruss, Thilo and Schönenberger, Helmut (1993) The choice of cytostatic in hyperthermic isolated limb perfusion. Chemosensitivity testing on five human melanoma cell lines. Chirurgisches Forum fuer Experimentelle und Klinische Forschung, pp. 89-94.

1992

Angerer, Erwin von and Erber, Sebastian (1992) 3-Alkyl-2-phenylbenzo[b]thiophenes: nonsteroidal estrogen antagonists with mammary tumor inhibiting activity. The Journal of steroid biochemistry and molecular biology 41 (3-8), pp. 557-562.

Polossek, T. and Ambros, R. and Angerer, S. von and Brandl, G. and Mannschreck, A. and Angerer, E. von (1992) 6-Alkyl-12-formylindolo[2,1-a]isoquinolines. Syntheses, estrogen receptor binding affinities, and stereospecific cytostatic activity. Journal of Medicinal Chemistry 35 (19), pp. 3537-3547.

Reile, Herta and Bernhardt, Günther and Koch, Marion and Schönenberger, Helmut and Hollstein, Michael and Lux, Franz (1992) Chemosensitivity of human MCF-7 breast cancer cells to diastereoisomeric diaqua(1,2-diphenylethylenediamine) platinum(II) sulfates and specific platinum accumulation. Cancer chemotherapy and pharmacology 30 (2), pp. 113-122.

Bernhardt, Günther and Müller, Richard and Gust, Ronald and Reile, Herta and Keller, Christoph and Spruss, Thilo and Schönenberger, Helmut (1992) Dichloro-[1-(hydroxyphenyl)-2-phenylethylenediamine]platinum(II) complexes: testing on the human ovarian cancer cell lines NIH: OVCAR3 and SK OV 3. Archiv der Pharmazie 325 (2), pp. 93-99.

Kager, M. and Spruss, T. and Schneider, M. R. and Angerer, E. von (1992) Dunning R3327-G prostate carcinoma of the rat: an appropriate model for drug evaluation. Journal of cancer research and clinical oncology 118 (5), pp. 334-338.

Grimm, Daniela and Hofstädter, Ferdinand and Bauer, Johann and Spruss, Thilo and Steinbach, Pia and Bernhardt, Günther and Menze, Rita (1992) Establishment and characterization of a human papillary thyroid carcinoma cell line with oxyphilic differentiation (ONCO-DG 1). Virchows Archiv. B, Cell pathology including molecular pathology 62 (2), pp. 97-104.

DiZio, J. P. and Carlson, K. E. and Bannochie, C. J. and Welch, M. J. and Angerer, E. von and Katzenellenbogen, J. A. (1992) Estrogen platinum-diamine complexes: preparation of a non-steroidal estrogen platinum-diamine complex labeled with platinum-191 and a study of its binding to the estrogen receptor in vitro and its tissue distribution in vivo. The Journal of steroid biochemistry and molecular biology 42 (3-4), pp. 363-373.

Buschauer, Armin and Baumann, Gert (1992) H_2-Agonisten des Arpromidin-Typs: Neue potentielle Arzneistoffe zur Behandlung der Herzinsuffizienz. In: Hirschelmann, R., (ed.) Entzündung und verwandte Reaktionen - Neue Erkenntnisse, neue Wirkstoffe. Jenapharm, Jena, pp. 192-203.

Baumann, Gert and Buschauer, Armin and Felix, Stefan B. (1992) Hemodynamic profile of arpromidine and its F_2-substituted derivatives in comparison to impromidine in congestive heart failure. Agents Actions Special Conference Issue,, C329-C332.

Bungardt, Edwin and Buschauer, Armin and Moser, Ulrich and Schunack, Walter and Lambrecht, Günter and Mutschler, Ernst (1992) Histamine H_1-receptors mediate vasodilation in guinea-pig ileum resistance vessels: Characterization by the use of computer-assisted videomicroscopy and new selective agonists. Eur. J. Pharmacol. 221, pp. 91-98.

Sellier, Christian and Elz, Sigurd and Buschauer, Armin and Schunack, Walter (1992) Histamine analogues: imidazolylalkylguanidines, synthesis and in vitro pharmacology. European Journal of Medicinal Chemistry 27, pp. 27-32.

Seifert, Roland and Höer, Ariane and Offermann, Stefan and Buschauer, Armin and Schunack, Walter (1992) Histamine increases Ca^2+ in dibutyryl cyclic AMP-differentiated HL-60 cells via H_1-receptors and is an incomplete secretagogue. Mol. Pharmacol. 42, pp. 227-234.

Seifert, Roland and Höer, Ariane and Schwaner, Ingo and Buschauer, Armin (1992) Histamine increases cytosolic Ca^2+ in HL-60 promyelocytes predominantly via H_2-receptors with an unique agonist/antagonist profile and induces functional differentiation. Molecular Pharmacology 42, pp. 235-241.

Beckenlehner, Karin and Bannke, Silke and Spruss, Thilo and Bernhardt, Günther and Schönenberger, Helmut and Schiess, Wilfried (1992) Hyaluronidase enhances the activity of adriamycin in breast cancer models in vitro and in vivo. Journal of cancer research and clinical oncology 118 (8), pp. 591-596.

Hirschfeld, Jürgen and Buschauer, Armin and Elz, Sigurd and Schunack, Walter and Ruat, Martial and Traiffort, Elisabeth and Schwartz, Jean-Charles (1992) Iodoaminopotentidine and related compounds: a new class of ligands with high affinity and selectivity for the histamine H_2-receptor. Journal of Medicinal Chemistry 35, pp. 2231-2238.

Klein-Tebbe, Jörg and Buschauer, Armin and Friese, Andrea and Schunack, Walter and Kunkel, G. (1992) Modulation of IgE-mediated histamine release from human leukocytes by a new class of histamine H_2-agonists. Agents Actions 35, pp. 185-191.

Michel, Martin C. and Buschauer, Armin (1992) Neuropeptide Y and its antagonists. Drugs Fut. 17, pp. 39-45.

Franke, Rainer and Buschauer, Armin (1992) Quantitative structure-activity relationships in histamine H_2-agonists related to impromidine and arpromidine. European Journal of Medicinal Chemistry 27, pp. 443-448.

Bernhardt, Günther and Reile, Herta and Birnböck, Herbert and Spruss, Thilo and Schönenberger, Helmut (1992) Standardized kinetic microassay to quantify differential chemosensitivity on the basis of proliferative activity. Journal of cancer research and clinical oncology 118 (1), pp. 35-43.

Buschauer, Armin and Friese-Kimmel, Andrea and Baumann, Gert and Schunack, Walter (1992) Synthesis and histamine H_2 agonistic activity of arpromidine analogues: replacement of the pheniramine-like moiety by non-heterocyclic groups. European Journal of Medicinal Chemistry 27, pp. 321-330.

Buschauer, Armin and Lachenmayr, Friedhelm and Schunack, Walter (1992) Synthesis and histamine H_2-receptor activity of heterocyclic impromidine analogues. Pharmazie 47, pp. 86-91.

Angerer, E. von and Birnböck, H. and Kager, M. and Maucher, A. (1992) The effect of a combination of zindoxifene and cisplatin on Dunning R3327-G prostatic carcinomas of the rat. Journal of cancer research and clinical oncology 118 (5), pp. 339-343.

Sellier, Christian and Elz, Sigurd and Buschauer, Armin and Schunack, Walter (1992) The effect of lipophilic substituents on the H_2-histaminergic activity of some close analogues of impromidine. Arch. Pharm. (Weinheim) 325, pp. 471-476.

Sellier, Christian and Elz, Sigurd and Buschauer, Armin and Schunack, Walter (1992) Zur Synthese von (Z)- und (E)-3-(1H-imidazol-4-yl)-2-propenamin und einigen 3-(1H-Imidazol-4-yl)propanaminen. Liebigs Ann. Chem. 1992, pp. 317-322.

Bernhardt, Günther and Gust, Ronald and Reile, Herta and vom Orde, Hans Dieter and Müller, Richard and Keller, Christoph and Spruß, Thilo and Schönenberger, Helmut and Burgemeister, Thomas and Mannschreck, Albrecht and Range, Klaus-Jürgen and Klement, Ulrich (1992) [1,2-Bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer. II. Synthesis and preliminary testing of the enantiomeric complexes. Journal of cancer research and clinical oncology 118 (3), pp. 201-208.

Bernhardt, Günther and Gust, Ronald and Reile, Herta and vom Orde, Hans Dieter and Müller, Richard and Keller, Christoph and Spruß, Thilo and Schönenberger, Helmut and Burgemeister, Thomas and Mannschreck, Albrecht and Range, Klaus Jürgen and Klement, Ulrich (1992) [1,2-Bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer. III. Detailed evaluation of the antitumor activity of the enantiomeric complexes on the human NIH:OVCAR-3 ovarian cancer cell line. Journal of cancer research and clinical oncology 118 (3), pp. 209-215.

1991

Bernhardt, Günther and Reile, Herta and Spruss, Thilo and Koch, Marion and Gust, Ronald and Schönenberger, Helmut and Hollstein, Michael and Lux, Franz and Engel, Jürgen (1991) D-17446. Drugs of the Future 16 (10), pp. 899-903.

Erber, S. and Ringshandl, R. and Angerer, E. von (1991) 2-Phenylbenzo[b]furans: relationship between structure, estrogen receptor affinity and cytostatic activity against mammary tumor cells. Anti-cancer drug design 6 (5), pp. 417-426.

Knebel, N. G. and Angerer, E. von (1991) 2-Phenylindole-linked [2-(aminoalkyl)pyridine]dichloroplatinum(II): complexes with a selective action on estrogen receptor positive mammary tumors. Journal of Medicinal Chemistry 34 (7), pp. 2145-2152.

Schiller, C. D. and Angerer, E. von and Schneider, M. R. (1991) 6,7-Dihydro-4H-indolones: synthesis and biological properties. Archiv der Pharmazie 324 (10), pp. 767-771.

Dove, Stefan and Franke, R. (1991) Activity data decomposition - levels, methods and principles. In: Silipo, C., (ed.) QSAR: Rational approaches in the design of bioactive compounds. Pharmacochemistry library, 16. Elsevier, Amsterdam, 37 - 40. ISBN 0-444-88839-X.

Brunner, Henri and Nerl, Georg and Angerer, Erwin von and Knebel, Norbert (1991) Antitumoraktive Platin(II)-Komplexe mit substituierten 2-Aminomethylpyridin-Liganden. Archiv der Pharmazie 324 (10), pp. 779-784.

Alisch, Rudi and Schulze, Frank and Buschauer, Armin and Schunack, Walter (1991) Arylalkylaminderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel. Schweizer Patentanmeldung 02193/91-6 (22.07.1991).

Spruß, Thilo and Bernhardt, Günther and Schickaneder, Edith and Schönenberger, Helmut (1991) Different response of murine and human mammary tumour models to a series of diastereoisomeric [1,2-bis(difluorophenyl) ethylenediamine]dichloroplatinum(II) complexes. Journal of cancer research and clinical oncology 117 (5), pp. 435-443.

Schneider, M. R. and Schiller, C. D. and Humm, A. and Angerer, E. von (1991) Effect of zindoxifene on experimental prostatic tumours of the rat. Journal of cancer research and clinical oncology 117 (1), pp. 33-36.

Bernhardt, Günther and Spruss, Thilo and Schönenberger, Helmut (1991) Einsatz menschlicher Tumorzellkulturen als Testmodelle bei der Entwicklung von Wirkstoffen für die Krebstherapie. Forum für interdisziplinäre Forschung : FIF 4, pp. 24-28.

Klein-Tebbe, Jörg and Schramm, J. and Bolz, M. and Gagné, H. and Josties, C. and Lipp, Ralph and Friese, Andrea and Stark, Holger and Zingel, Volkmar and Buschauer, Armin and Fricker, Gert (1991) Influence of histamine H_1, H_2, and H_3 agonists and antagonists on IgE mediated histamine release from human basophils. In: Ring, J. and Przbilla, B., (eds.) New Trends in Allergy III. Springer, Berlin Heidelberg, pp. 152-157.

Altman, Janina and Castrillo, Thais and Beck, Wolfgang and Bernhardt, Günther and Schönenberger, Helmut (1991) Metal complexes with biologically important ligands. 62. Platinum(II) complexes of 3-(2-aminoethoxy)estrone and -estradiol. Inorganic Chemistry 30 (21), pp. 4085-4088.

Dove, Stefan and Franke, R. (1991) Model-based LFER parameters and QSAR of ligand-ß-adrenoceptor interactions. I. Equilibrium models and parameters of ß-adrenergic effectuation. Quantitative structure activity relationships 10 (1), pp. 16-22.

Dove, Stefan and Franke, R. (1991) Model-based LFER parameters and QSAR of ligand-ß-adrenoceptor interactions. II. Estimation and QSAR of agonistic potency and receptor affinity in a series of ß-adrenergic phenethanolamines. Quantitative structure activity relationships 10 (1), pp. 23-31.

Nishino, Y. and Schneider, M. R. and Michna, H. and Angerer, E. von (1991) Pharmacological characterization of a novel oestrogen antagonist, ZK 119010, in rats and mice. The Journal of endocrinology 130 (3), pp. 409-414.

Ruat, Martial and Traiffort, E. and Bouthenet, M. L. and Pollard, H. and Moreau, J. and Schwartz, Jean-Charles and Martinez-Mir, I. and Palacios, J. M. and Hirschfeld, Jürgen and Buschauer, Armin and Schunack, Walter and Tertiuk, W. and Ganellin, C. Robin (1991) Reversible and irreversible labelling of H_1- and H_2-receptors using novel [^125I]probes. Agents Actions Suppl. 33, pp. 123-144.

Buschauer, Armin and Baumann, Gert (1991) Structure-activity relationships of histamine H_2-agonists, a new class of positive inotropic drugs. Agents Actions Suppl. 33, pp. 231-256.

Büyüktimkin, Servet and Buschauer, Armin and Schunack, Walter (1991) Synthese und H_1/H_2-antihistaminische Wirkung w-[2-Aryl-2,3-dihydro-4(1H)-chinazolinon-1-yl]alkyl-substituierter Harnstoffe und Cyanoguanidine. Arch. Pharm. (Weinheim) 324, pp. 291-295.

Buschauer, Armin and Lachenmayr, Friedhelm and Schunack, Walter (1991) Synthesis and histamine H_2-agonistic activity of ring-substituted phenyl analogues of impromidine. Pharmazie 46, pp. 841-845.

Dove, Stefan (1991) Theoretische Methoden in der Wirkstofforschung - Möglichkeiten und Grenzen. Medicamentum 32, pp. 196-205.

Felix, Stefan B. and Buschauer, Armin and Baumann, Gert (1991) Therapeutic value of H_2-receptor stimulation in congestive heart failure. Hemodynamic effects of BU-E-76, BU-E-75 and arpromidine (BU-E-50) in comparison to impromidine. Agents Actions Suppl. 33, pp. 257-269.

Reile, Herta and Spruß, Thilo and Bernhardt, Günther and Müller, Richard and Gust, Ronald and Schönenberger, Helmut (1991) Tumor inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes. Part IV: Biological evaluation--in vivo studies on the P 388 leukemia. Archiv der Pharmazie 324 (7), pp. 405-409.

Neugebauer, Edmund and Buschauer, Armin (1991) Verwendung von Guanidinderivaten zur Herstellung eines Arzneimittels zur Behandlung des Sepsis-Syndroms, des Sepsis-like Syndroms und des septischen Schocks. Deutsche Patentanmeldung P 41 19 696.1 (14.6.1991); Offen­legungsschrift DE 41 19 696 A 1 (17.12.1992); PCT Internat. Veröffentlichung WO 92/22295 (23.12.1992).

1990

Angerer, E. von and Knebel, N. and Kager, M. and Ganss, B. (1990) 1-(aminoalkyl)-2-phenylindoles as novel pure estrogen antagonists. Journal of medicinal chemistry 33 (9), pp. 2635-2640.

Erber, Sebastian and Angerer, Erwin von (1990) 2-phenylindole-linked nitroimidazoles as potential radiosensitizers for estrogen receptor positive tumors. Archiv der Pharmazie 323 (9), pp. 591-594.

Schiller, Claus D. and Schneider, Martin R. and Angerer, Erwin von (1990) 3-(Cyclohexenonyl)-4-(4-hydroxyphenyl)-hexanes: antiandrogenes derived from the estrogen hexestrol. Archiv der Pharmazie 323 (7), pp. 417-420.

Mörsdorf, Peter and Engler, Heidrun and Schickaneder, Helmut and Buschauer, Armin and Schunack, Walter and Baumann, Gert (1990) Cardiohistaminergics - new developments in histamine H_2-agonists. Drugs of the Future 15, pp. 919-933.

Burde, Rahel and Buschauer, Armin and Seifert, Roland (1990) Characterization of histamine H_2-receptors in human neutrophils with a series of guanidine analogues of impromidine: Are cell type-specific H_2-receptors involved in the regulation of NADPH oxidase? Naunyn-Schmiedeberg's Archives of Pharmacology 341, pp. 455-461.

Reile, Herta and Birnböck, Herbert and Bernhardt, Günther and Spruß, Thilo and Schönenberger, Helmut (1990) Computerized determination of growth kinetic curves and doubling times from cells in microculture. Analytical biochemistry 187 (2), pp. 262-267.

Meindl, Wolfgang and Friese-Kimmel, Andrea and Lachenmayr, Friedhelm and Buschauer, Armin and Schunack, Walter (1990) Der Einfluß von Agonisten und Antagonisten des Histamin-H_1- und H_2-Rezeptors auf das Wachstum von Mycobacterium tuberculosis H 37 Ra. Arch. Pharm. (Weinheim) 323, pp. 267-272.

Stein, R. C. and Dowsett, M. and Cunningham, D. C. and Davenport, J. and Ford, H. T. and Gazet, J. C. and Angerer, E. von and Coombes, R. C. (1990) Phase I/II study of the anti-oestrogen zindoxifene (D16726) in the treatment of advanced breast cancer. A Cancer Research Campaign Phase I/II Clinical Trials Committee study. British journal of cancer 61 (3), pp. 451-453.

Bednarski, P. J. and Gust, R. and Spruss, T. and Knebel, N. and Otto, A. and Farbel, M. and Koop, R. and Holler, E. and Angerer, E. von and Schönenberger, H. (1990) Platinum compounds with estrogen receptor affinity. Cancer treatment reviews 17 (2-3), pp. 221-231.

Ruat, Martial and Traiffort, Elisabeth and Bouthenet, M. L. and Schwartz, Jean-Charles and Hirschfeld, Jürgen and Buschauer, Armin and Schunack, Walter (1990) Reversible and irreversible labeling and autoradiographic localization of the cerebral histamine H_2-receptor. Proc. Natl. Acad. Sci. USA 87, pp. 1658-1662.

Birnböck, H. and Angerer, E. von (1990) Sulfate derivatives of 2-phenylindoles as novel steroid sulfatase inhibitors. An in vitro study on structure-activity-relationship. Biochemical pharmacology 39 (11), pp. 1709-1713.

Erber, S. and Birnböck, H. and Angerer, E. von (1990) Synthesis and biological properties of a 1-(6-aziridinylhexyl)-2-phenylindole, a potential fluorescence label for estrogen receptors. Archiv der Pharmazie 323 (8), pp. 459-463.

Reile, Herta and Spruß, Thilo and Müller, Richard and Gust, Ronald and Bernhardt, Günther and Schönenberger, Helmut and Engel, Jürgen (1990) Tumor inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes, III: Evaluation of the mammary tumor inhibiting properties. Archiv der Pharmazie 323 (5), pp. 301-306.

Reile, Herta and Müller, Richard and Gust, Ronald and Laske, Reiner and Krischke, Walter and Bernhardt, Günther and Spruss, Thilo and Jennerwein, Margaretha and Engel, Jürgen and Seeber, Siegfried (1990) Tumor inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes. Part II: Biological evaluation-in vitro studies on the P 388 D1 leukemia cell line. Archiv der Pharmazie 323 (3), pp. 133-140.

vom Orde, Hans Dieter and Reile, Herta and Müller, Richard and Gust, Ronald and Bernhardt, Günther and Spruß, Thilo and Schönenberger, Helmut and Burgemeister, Thomas and Mannschreck, Albrecht (1990) Tumor-inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes. V. Synthesis and evaluation of enantiomeric [1,2-bis-(4-fluorophenyl)ethylenediamine]dichloroplatinum(II) complexes. Journal of cancer research and clinical oncology 116 (5), pp. 434-438.

Müller, Richard and Gust, Ronald and Bernhardt, Günther and Keller, Christoph and Schönenberger, Helmut and Seeber, Siegfried and Osieka, Reinhardt and Eastman, Alan and Jennerwein, Margaretha (1990) [DL-1,2-bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer. Journal of cancer research and clinical oncology 116 (3), pp. 237-244.

1989

Dove, Stefan (1989) Beiträge zu quantitativen Struktur-Wirkungs-Beziehungen und zur Entwicklung von Modellen der Ligand-Rezeptor-Wechselwirkung von ß-Agonisten und -Antagonisten. Habilitation, Akademie der Wissenachften der DDR.

Knebel, N. and Schiller, C. D. and Schneider, M. R. and Schönenberger, H. and Angerer, E. von (1989) Carrier mediated action of platinum complexes on estrogen receptor positive tumors. European journal of cancer & clinical oncology 25 (2), pp. 293-299.

Buschauer, Armin (1989) Entwicklung neuer positiv inotroper Arzneistoffe: Suche nach einem Digitalisersatz. Pharm. Ztg. Wiss. 2/134, pp. 3-16.

Buschauer, Armin and Schunack, Walter and Arrang, Jean-Michel and Garbarg, Monique (1989) Histamine Receptors. In: Williams, M. and Glennon, R. A. and Timmermans, P. B. M. W. M., (eds.) Receptor Pharmacology and Function. Series Clinical Pharmacology (series Ed. M. Weiner), 13. Marcel Dekker Inc., New York, pp. 293-347.

Burde, Rahel and Seifert, Roland and Buschauer, Armin and Schultz, Günther (1989) Histamine inhibits activation of human neutrophils and HL-60 leukemic cells via H_2-receptors. Naunyn-Schmiedeberg's archives of pharmacology 340, pp. 671-678.

Angerer, E. von and Birnböck, H. and Knebel, N. (1989) Platinum complexes with a selective action on estrogen receptor-positive mammary tumors. Anti-cancer drug design 4 (1), pp. 21-35.

Dove, Stefan and Franke, R. (1989) Some Problems of the Interpretation of Receptorologic Data in QSAR Work. In: Fauchere, J. L., (ed.) QSAR: Quantitative Structure-Activity Relationships in Drug Design. Progress in clinical and biological research, 291. A. R. Liss Inc., New York, 31 - 35. ISBN 0-8451-5141-X.

Büyüktimkin, Servet and Buschauer, Armin and Schunack, Walter (1989) Synthese und pharmakologische Aktivität von 2-Aryl-1-((3-(imidazol-4-yl)propyl)guanidinoalkyl)-2,3-dihydro-4(1H)-chinazolinonen. Arch. Pharm. 322, pp. 115-118.

Buschauer, Armin (1989) Synthesis and in vitro pharmacology of arpromidine and related Phenylpyridyl­alkyl­guanidines, a potential new class of positive inotropic drugs. J. Med. Chem. 32, pp. 1963-1970.

Pawlowski, Maciej and Buschauer, Armin and Schunack, Walter (1989) Synthesis of Some 9-(Aminoalkyl)-6,7-dihydropyrimido[2,1-f]purine-2,4,8-(1H,3H,9H)-triones. Arch. Pharm. (Weinheim) 322, pp. 447-449.

Mueller, Richard and Gust, Ronald and Jennerwein, Margaretha and Reile, Herta and Laske, Reiner and Krischke, Walter and Bernhardt, Günther and Spruss, Thilo and Engel, Juergen and Schönenberger, Helmut (1989) Tumor inhibiting [1,2-bis(fluorophenylethylenediamine]platinum(II) complexes. Part I. Synthesis. European Journal of Medicinal Chemistry 24 (4), pp. 341-348.

Baumann, Gert and Buschauer, Armin and Permanetter, Bernhard and Schunack, Walter (1989) Wiederherstellung der b_1-adrenergen Ansprechbarkeit bei Patienten mit Myokardinsuffizienz. In: Löllgen, H. and Just, H. and Meinertz, T., (eds.) Katecholamine in der Notfall- und Intensivmedizin. Perimed Verlag, Erlangen, pp. 28-42.

Buschauer, Armin (1989) Zur Synthese primärer w-Phenyl-w-pyridylalkylamine. Arch. Pharm. (Weinheim) 322, pp. 165-171.

1988

Bernhardt, Günther and Disteche, A. and Jaenicke, Rainer and Koch, B. and Luedemann, Hans-Dietrich and Stetter, Karl Otto (1988) EFFECT OF CARBON-DIOXIDE AND HYDROSTATIC-PRESSURE ON THE PH OF CULTURE MEDIA AND THE GROWTH OF METHANOGENS AT ELEVATED-TEMPERATURE. Applied Microbiology and Biotechnology 28 (2), pp. 176-181.

Mohr, R. and Buschauer, Armin and Schunack, Walter (1988) Basisch substituierte Aryloxyalkylguanidine und Analoge mit H_2-antagonistischer Wirkung. Arch. Pharm. (Weinheim) 321, pp. 221-227.

Elz, Sigurd and Kimmel, Ursula and Buschauer, Armin and Schunack, Walter (1988) Halogenderivate von N-[3-(Imidazol-4-yl)propyl]-N'-(2-phenylthioalkyl)guanidinen. Sci. Pharm. 56, pp. 229-234.

Bernhardt, Günther and Jaenicke, Rainer and Lüdemann, Hans-Dietrich and König, Helmut and Stetter, Karl Otto (1988) High Pressure Enhances the Growth Rate of the Thermophilic Archaebacterium Methanococcus thermolithotrophicus without Extending Its Temperature Range. Applied and environmental microbiology 54 (5), pp. 1258-1261.

Buschauer, Armin (1988) Imidazolylalkylguanidine mit Diaryl-Partialstrukturen. Sci. Pharm. 56, pp. 81-88.

Baumann, Gert and Buschauer, Armin and Permanetter, Bernhard and Schunack, Walter (1988) Neue Aspekte zur Therapie der Myokardinsuffizienz. Inn. Med. 15 (Sonderausg.), pp. 30-38.

Buschauer, Armin (1988) Phenoxy- and Phenylthioalkylguanidines - Synthesis and in vitro Pharmacology. Eur. J. Med. Chem. 23, pp. 1-6.

Knebel, N. and Angerer, E. von (1988) Platinum complexes with binding affinity for the estrogen receptor. Journal of medicinal chemistry 31 (9), pp. 1675-1679.

Jaenicke, Rainer and Bernhardt, Günther and Lüdemann, Hans-Dietrich and Stetter, Karl Otto (1988) Pressure-Induced Alterations in the Protein Pattern of the Thermophilic Archaebacterium Methanococcus thermolithotrophicus. Applied and environmental microbiology 54 (10), pp. 2375-2380.

Bercher, H. and Dove, Stefan and Ramanauskas, J. J. and Repcyte, M. A. and Gruendling, J. and Gruska, A. and Grisk, A. (1988) Quantitative structure-activity studies on 2-alkylaminoethoxy-1,4-benzodioxanes with local anesthetic activity. Wissenschaftliche Zeitschrift der Ernst-Moritz-Arndt-Universität Greifswald, Medizinische Reihe 37 (2-3), pp. 35-37.

Büyüktimkim, Nadir and Buschauer, Armin (1988) Separation and Determination of some Amino Acid Ester Enantiomers on TLC after Derivatization with Activated (S)-(+)-Naproxen. J. Chromatogr. 450, pp. 281-283.

Buschauer, Armin (1988) Synthese positiv inotroper Substanzen: Aryloxyalkylguanidine. Arch. Pharm. (Weinheim) 321, pp. 281-285.

Buschauer, Armin (1988) Synthese positiv inotroper Substanzen: Imidazolylpropylguanidine mit Pyridin-Partialstruktur,. Arch. Pharm. (Weinheim) 321, pp. 415-418.

Büyüktimkin, Servet and Buschauer, Armin and Schunack, Walter (1988) Synthese von 1-(Aminoalkyl)-2-aryl-2,3-dihydro-4(1H)-chinazolinonen. Arch. Pharm. (Weinheim) 321, pp. 833-834.

Keller, Frank and Buschauer, Armin and Schunack, Walter (1988) Synthese, Racemattrennung und pharmakologische Wirkung chiraler H_2-Antagonisten vom Aminomethylphenoxypropylamin-Typ. Pharm. Ztg. Wiss. 1/113, pp. 48-55.

1987

Angerer, E. von and Strohmeier, J. (1987) 2-Phenylindoles. Effect of N-benzylation on estrogen receptor affinity, estrogenic properties, and mammary tumor inhibiting activity. Journal of medicinal chemistry 30 (1), pp. 131-136.

Schneider, M. R. and Angerer, E. von and Höhn, W. and Sinowatz, F. (1987) Antitumor activity of antiestrogenic phenylindoles on experimental prostate tumors. European journal of cancer & clinical oncology 23 (7), pp. 1005-1015.

Buschauer, Armin (1987) Arylmethylthioalkylguanidin-Derivate, Synthese und pharmakologische Wirkung. Arzneim.-Forsch. 37, pp. 1008-1012.

Birnböck, H. and Ringshandl, R. and Angerer, E. von (1987) Chromatographic analysis of the new antiestrogen zindoxifene and its metabolites in biological material. Journal of chromatography 414 (1), pp. 235-241.

Mörsdorf, Peter and Schickaneder, Helmut and Pfahlert, Volker and Engler, Heidrun and Buschauer, Armin and Schunack, Walter (1987) Guanidin-Carbonsäureester, Verfahren zu ihrer Herstellung und diese Verbin­dun­gen enthaltende Arzneimittel. Patentanmeldung 37 26 381.1 (7.8.1987). , Deutsche Offenlegungsschrift DE 37 26 381 (8.2.1989); EP 0 302 164 (8.2.1989).

Bernhardt, Günther and Jaenicke, Rainer and Lüdemann, Hans-Dietrich (1987) High-Pressure Equipment for Growing Methanogenic Microorganisms on Gaseous Substrates at High Temperature. Applied and environmental microbiology 53 (8), pp. 1876-1879.

Baumann, Gert and Permanetter, Bernhard and Buschauer, Armin and Wirtzfeld, Alexander and Schunack, Walter (1987) Mögliche Bedeutung einer kardialen H_2-Rezeptor Stimulation bei Katecholamin-refraktärem Myokardversagen unterschiedlicher Ätiologie. In: Brisse, B. and Bender, F., (eds.) Autonome Innervation des Herzens - Myokardiale Hypoxie. Steinkopff-Verlag, Darmstadt, pp. 183-194.

Buschauer, Armin (1987) Synthese und pharmakologische Wirkung substituierter Imidazolylalkyl- und Thiazolylalkylguanidine. Arzneim.-Forsch. 37, pp. 1003-1007.

Buschauer, Armin (1987) Synthese von N-Benzoyl- und N-Methansulfonyl-diphenylimidocarbonat. Arch. Pharm. (Weinheim) 320, pp. 377-378.

Strohmeier, J. and Angerer, E. von (1987) Synthesis and estrogen receptor affinity of 2,3-diarylindoles. Archiv der Pharmazie 320 (5), pp. 407-417.

1986

Buschauer, Armin and Schickaneder, Helmut and Elz, Sigurd and Schunack, Walter and Szelenyi, Istvan and Baumann, Gert and Ahrens, K.-H. (1986) Guanidinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthal­tende Arzneimittel. Patentanmeldung P 35 12 084.3 (2.4.1985), Offenlegungsschrift DE 35 12 084 A.

Mohr, Rainer and Buschauer, Armin and Schunack, Walter (1986) 1,3,5-Triazin-2,4-diamine und -2,4,6-triamine mit H2-antagonistischer Wirkung. Arch. Pharm. (Weinheim) 319, pp. 878-885.

Schickaneder, Helmut and Mörsdorf, Peter and Buschauer, Armin and Schunack, Walter and Engler, Heidrun and Vergin, Hartmut and Ahrens, K.-H. (1986) 1,4-Dihydropyridinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthal­tende Arzneimittel. Patentanmeldung P 36 21 104.4 (24.6.1986), Offenlegungsschrift DE 36 21 104 A 1 (7.1.1988)..

Angerer, Erwin von and Prekajac, Jelica (1986) Benzo[a]carbazole derivatives. Synthesis, estrogen receptor binding affinities, and mammary tumor inhibiting activity. Journal of medicinal chemistry 29 (3), pp. 380-386.

Dove, Stefan and Koch, A. and Franke, R. (1986) Comparative QSAR Studies in a Series of 4-(Imidazol-2'-yl)phenoxypropanolamines and Pyrid-2-yloxypropanolamines with Antihypertensive, Vasodilating and ß-Blocking Properties. Acta Pharmaceutica Jugoslavica 36 (2), pp. 119-128.

Bernhardt, Günther (1986) Hochdruckuntersuchungen an thermophilen Bakterien. PhD, Regensburg, Universität.

Buschauer, Armin and Schunack, Walter and Baumann, Gert and Ahrens, K.-H. (1986) Neue Imidazolylguanidinderivate, Verfahren zu ihrer Herstellung und diese Verbin­dungen enthaltende Arzneimittel. Patentanmeldung P 36 31 334.3 (15.9.1986), Offenlegungsschrift DE 36 31 334 A1 (17.3.1988)..

Schneider, M. R. and Angerer, E. von and Prekajac, J. and Brade, W. P. (1986) Studies on the mammary tumor-inhibiting effects of diethylstilbestrol and its mono- and diphosphate. Journal of cancer research and clinical oncology 111 (2), pp. 110-114.

Buschauer, Armin and Krämer, Irene and Schunack, Walter (1986) Synthese und H_2-antagonistische Wirkung 3-(3-piperidinomethyl-phenoxy)propyl-substituierter Kohlensäurederivate und Analoge. Arch. Pharm. (Weinheim) 319, pp. 434-443.

1985

Angerer, Erwin von and Prekajac, Jelica and Schneider, Martin R. (1985) D-15413. Drugs of the future 12 (4), pp. 1023-1026.

Angerer, Erwin von and Engel, Jürgen and Schneider, Martin R. and Sherdrick, W. (1985) D-16726. Drugs of the future 10 (4), pp. 281-285.

Buschauer, Armin (1985) 4-Aminopyrimidine mit H2-antihistaminischer Aktivität. Pharm. Ztg. Sci. Ed. 130, pp. 2067-2070.

Dove, Stefan and Coats, E. and Scharfenberg, P. and Franke, R. (1985) 7-Substituted 4-Hydroxychinoline-3-carboxylic Acids as Inhibitors of Dehydrogenase Enzymes and of the Respiration of Ehrlich Ascites Tumor Cells: Multivariate Analysis and Quantitative Structure-Activity Relationships for Polar Substitutens. Journal of Medicinal Chemistry 28 (4), pp. 447-451.

Buschauer, Armin and Schickaneder, Helmut and Schunack, Walter and Szelenyi, Istvan and Ahrens, K.-H. (1985) Arylalkylguanidinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel. Patentanmeldung P 35 28 214.2 (6.8.1985), Offenlegungsschrift DE 35 28 214 (12.2.1987).

Barth, A. and Neubert, K. and Schwarz, G. and Fischer, G. and Dove, Stefan and Franke, R. (1985) Enzymatic Hydrolyses of Alanyl-alanine-anilides by Dipeptidyl Peptidase IV. In: Seydel, J. K., (ed.) QSAR and Strategies in the Design of Bioactive Compounds - Proceedings of the 5th European Symposium on QSAR. Verlag Chemie, Weinheim, 318 - 321. ISBN 3-527-26306-3; 0-89573-433-8.

Buschauer, Armin and Schickaneder, Helmut and Schunack, Walter and Szelenyi, Istvan and Ahrens, Kurt-Henning (1985) Heteroarylalkylguanidinderivate, Verfahren zu ihrer Herstellung und diese Verbin­dungen enthaltende Arzneimittel. Patentanmeldung P 35 28 215.0 (6.8.1985), Offenlegungsschrift DE 35 28 215 (12.2.1987).

Schunack, Walter and Buschauer, Armin and Büyüktimkim, Servet and Dziuron, Peter and Elz, Sigurd and Gerhardt, Günter and Lebenstedt, Ernst and Lennartz, Hans-Gerd and Schwarz, Siegfried and Spitzhoff, Margrit and Steffens, Robert (1985) 2. Histamine agonists - chemistry and structure-activity relationships. In: Dahlbom, R. and Nilsson, J. L. G., (eds.) VIIIth International Symposium on Medicinal Chemistry. Swedish Pharmaceutical Press, Stockholm, pp. 169-182.

Strohmeier, J. and Angerer, E. von (1985) Hydroxy-3-(hydroxyphenyl)indoles. Relationship between structure and estrogen receptor affinity. Archiv der Pharmazie 318 (5), pp. 421-431.

Buschauer, Armin and Schickaneder, Helmut and Schunack, Walter and Elz, Sigurd and Szelenyi, Istvan and Baumann, Gert and Ahrens, K.-H. (1985) Imidazolylalkylguanidine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel. Patentanmeldung 85 114 205.9 (12.11.1985), Eur. Pat. Appl. EP 0 199 845 (5.11.1986).

Buschauer, Armin and Schunack, Walter (1985) Isocimetidin und Analoge. Arzneim.-Forsch. 35, pp. 1223-1224.

Buschauer, Armin and Postius, S. and Szelenyi, Istvan and Schunack, Walter (1985) Isohistamine und Homologe als Bausteine von H_2-Antagonisten. Arzneim.-Forsch. 35, pp. 1025-1029.

Dove, Stefan and Kühne, R. and Franke, R. (1985) On the Application of Principal Component and Factor Analysis in QSAR Work. In: Tichy, M., (ed.) QSAR in Toxicology and Xenobiochemistry - Proceedings of a Symposium. Pharmacochem. Library, 8. Elsevier, Amsterdam, pp. 277-286.

Schwarz, G. and Michel, H.-J. and Dove, Stefan (1985) Quantitative Struktur-Wirkungs-Analyse von Phosphorsäurephenylesterdiamid-Derivaten mittels Hauptkomponentenanalyse. Speziell Agrochemie : Forschung 85 (3), pp. 1-8.

Hartmann, R. W. (1985) TETRAMETHYLHES. Drugs of the Future 10, pp. 48-49.

Angerer, E. von and Prekajac, J. and Schneider, M. R. and Berger, M. R. (1985) The inhibitory effect of 4-chloro-2-(2,6-dichloro-4-hydroxyphenyl)-1-ethyl-6-hydroxyindole (D 15413) on estrogen-dependent mammary tumors. Journal of cancer research and clinical oncology 110 (3), pp. 216-220.

Angerer, E. von and Prekajac, J. and Berger, M. (1985) The inhibitory effect of 5-acetoxy-2-(4-acetoxyphenyl)-1-ethyl-3-methylindole (D 16726) on estrogen-dependent mammary tumors. European journal of cancer & clinical oncology 21 (4), pp. 531-537.

1984

Buschauer, Armin and Schunack, Walter (1984) (8,9-Dihydro-7H-imidazo[1,2-c][1,3]diazepin-H)-one, -5(6H)-thione und -5(6H)-yliden­cyanamide. J. Heterocycl. Chem. 21, pp. 753-757.

Angerer, E. von and Prekajac, J. and Strohmeier, J. (1984) 2-Phenylindoles. Relationship between structure, estrogen receptor affinity, and mammary tumor inhibiting activity in the rat. Journal of medicinal chemistry 27 (11), pp. 1439-47.

Buschauer, Armin and Sattler, Hans-Joachim and Schunack, Walter (1984) 7,8-Dihydroimidazo[1,2-c]pyrimidin-5(6H)-one, -5(6H)-thione und -5(6H)-yliden­cyanamide. Chem. Ber. 117, pp. 2597-2614.

Angerer, Erwin von and Holler, Eggehard and Schönenberger, Helmut and Schönenberger, Reinhard (1984) Antineoplastic drugs. In: Smith, Donald F., (ed.) Handbook of stereoisomers: Therapeutic drugs. CRC Press, Boca Raton, pp. 247-284. ISBN 0-8493-3421-7.

Meindl, Wolfgang R. and Angerer, Erwin von and Schönenberger, Helmut and Ruckdeschel, Gotthard (1984) Benzylamines: synthesis and evaluation of antimycobacterial properties. Journal of medicinal chemistry 27 (9), pp. 1111-1118.

Luedemann, Hans-Dietrich and Bernhardt, Günther and Jaenicke, Rainer and Koenig, Helmut and Stetter, Karl Otto (1984) Biomolecules are unstable under "black smoker" conditions. Naturwissenschaften 71 (11), pp. 583-586.

Angerer, Erwin von (1984) Development of new drugs for endocrine tumour chemotherapy. Cancer treatment reviews 11 Suppl A, pp. 147-153.

Wappes, B. and Jennerwein, M. and Angerer, E. von and Schönenberger, H. and Engel, J. and Berger, M. and Wrobel, K. H. (1984) Dichloro[1,2-bis(4-hydroxyphenyl)ethylenediamine]platinum(II) complexes: an approach to develop compounds with a specific effect on the hormone-dependent mammary carcinoma. Journal of medicinal chemistry 27 (10), pp. 1280-1286.

Angerer, Erwin von (1984) Entwicklung neuer endokrin wirksamer Tumorchemotherapeutika. In: Seeber, Siegfried and Osieka, Reinhardt and Sack, H. and Schönenberger, Helmut, (eds.) Das Resistenzproblem bei der Chemo- und Radiotherapie maligner Tumoren: Grundlagen und Klinik. Beiträge zur Onkologie, 18. Karger, Basel, pp. 83-92. ISBN 3-8055-3801-4.

Buschauer, Armin and Wegner, Kurt and Schunack, Walter (1984) Isohistamine. Arch. Pharm. (Weinheim) 317, pp. 9-14.

Franke, R. and Streich, W.-J. and Dove, Stefan (1984) On the Evaluation of Structural Activity Patterns. In: Seydel, J. K., (ed.) QSAR and Strategies in the Design of Bioactive Compounds - Proceedings of the 5th European Symposium on QSAR. VCH, Weinheim, 30 - 38. ISBN 3-527-26306-3; 0-89573-433-8.

Dove, Stefan and Franke, R. and Oehme, P. (1984) QSAR in DBH-Blocking and Hypotensive Fusaric Acid Derivatives. In: Kuchar, M., (ed.) QSAR in Design of Bioactive Compounds - Proceedings of the First International Telesymposium on Medicinal Chemistry. J. R. Prous Int. Publ., Barcelona, 117 - 134.

Weidhase, R. and Welker, P. and Neubert, K. and Dove, Stefan and Yoshimoto, T. and Tsuru, D. and Barth, A. (1984) Similarities of the substrate cleavage catalyzed by proline specific endopeptidase and dipeptidyl peptidase IV. Pharmazie 39 (12), pp. 835-837.

Wappes, B. and Jennerwein, M. and Angerer, E. von and Engel, J. and Schönenberger, H. and Brunner, H. and Schmidt, M. and Berger, M. and Schmähl, D. and Seeber, S. (1984) The tumor-inhibiting effect of isomeric dichloro(diphenylethylenediamine)platinum(II) complexes. Journal of cancer research and clinical oncology 107 (1), pp. 15-20.

1983

Angerer, Erwin von and Prekajac, Jelica (1983) 2-(Hydroxyphenyl)indoles: a new class of mammary tumor-inhibiting compounds. Journal of Medicinal Chemistry 26 (1), pp. 113-116.

Buschauer, Armin and Wegner, Kurt and Schunack, Walter (1983) 1,n-Bis(2-imidazolyl)alkane. Arch. Pharm. (Weinheim) 316, pp. 515-520.

Angerer, Erwin von and Prekajac, Jelica (1983) 2-(Hydroxyphenyl)indoles: a new class of mammary tumor inhibiting compounds. Journal of medicinal chemistry 26 (1), pp. 113-116.

Oehlke, J. and Schrötter, E. and Dove, Stefan and Schick, H. and Niedrich, H. (1983) Darstellung einiger 4- und 5-substituierter Pyridin-2-Carbonsäuren als Fusarsäureanaloga. Pharmazie 38 (9), pp. 591-594.

Elz, Sigurd and Buschauer, Armin and Dräger, M. and Schunack, Walter (1983) Darstellung, Eigenschaften und Kristallstruktur der N-[2-(4,5,6,7-Tetrahydro-2-benzimidazolyl)ethyl]phthalamidsäure. Z. Naturforsch. 38b, pp. 1203-1207.

Buschauer, Armin and Schunack, Walter (1983) Die Struktur des N(pi)-Methylisohistamins - Eine Richtigstellung. Arch. Pharm. (Weinheim) 316, pp. 891-894.

Franke, R. and Kühne, R. and Dove, Stefan (1983) Drug Design. Dependence of hydrophobicity on solvent and structure. In: Dearden, John C., (ed.) Quantitative Approaches to Drug Design. Pharmacochemistry library, 6. Elsevier, Amsterdam, 15 - 32. ISBN 0-444-42200-5.

Oehlke, J. and Schrötter, E. and Piesche, L. and Dove, Stefan and Niedrich, H. (1983) Kupfer-Komplexbildungskonstanten einiger Fusarsäureanaloga. Pharmazie 38 (9), pp. 624-628.

Franke, R. and Schwarz, G. and Dove, Stefan and Dietrich, A. and Klinger, W. (1983) Multivariate Struktur-Wirkungs-Analyse (QSWA) für Enzyminduktoren: Polychlorierte Biphenyle. Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriumsdiagnostik 122 (5), pp. 459-464.

1982

Angerer, Erwin von (1982) Effect of N,N'-diethyl-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamines on the DMBA-induced mammary carcinoma of the rat. Journal of Medicinal Chemistry 25 (11), pp. 1374-1377.

Angerer, Erwin von and Egginger, Guenter and Kranzfelder, Gerhard and Bernhauer, Horst and Schönenberger, Helmut (1982) N,N'-Dialkyl-1,2-bis(hydroxyphenyl)ethylenediamines and N,N'-dialkyl-4,5-bis(4-hydroxyphenyl)imidazolidines. Syntheses and evaluation of their mammary tumor inhibiting activity. Journal of Medicinal Chemistry 25 (7), pp. 832-837.

Schneider, M. R. and Angerer, E. von and Schönenberger, H. and Michel, R. T. and Fortmeyer, H. P. (1982) 1,1,2-triphenylbut-1-enes: relationship between structure, estradiol receptor affinity, and mammary tumor inhibiting properties. Journal of medicinal chemistry 25 (9), pp. 1070-7.

Kranzfelder, G. and Hartmann, R. W. and Angerer, E. von and Schönenberger, H. and Bogden, A. E. (1982) 3,4-bis(3'-hydroxyphenyl)hexane--a new mammary tumor-inhibiting compound. Journal of cancer research and clinical oncology 103 (2), pp. 165-180.

Schneider, Martin R. and von Angerer, Erwin and Schönenberger, Helmut (1982) 5-Acetoxy-2-(3-acetoxyphenyl)-3-ethyl-1-methyl-1H-indene: a new mammary tumor inhibiting compound. European journal of medicinal chemistry 17 (3), pp. 245-248.

Meindl, Wolfgang and von Angerer, Erwin and Ruckdeschel, Gotthard and Schönenberger, Helmut (1982) Antimykobakterielle N-Alkylbenzylamine: Synthese und Testung von 4-Aminomethyl-2-hydroxy-benzoesaure und Homologen

Antimycobacterial N-alkylbenzylamines: synthesis and testing of 4-aminomethyl-2-hydroxybenzoic acid and its homologs.
Archiv der Pharmazie 315 (11), pp. 941-946.

Buschauer, Armin and Wegner, Kurt and Schunack, Walter (1982) Basisch substituierte Cimetidin-Analoge. Eur. J. Med. Chem. - Chim. Ther. 17, pp. 505-508.

Dove, Stefan and Franke, Rainer and Kern, Eedgar and Schuster, Ggottfried and Kochmann, Werner and Steinke, Walter (1982) Diskriminanzanalytische Untersuchungen zur antiphytoviralen Aktivität einer Serie substituierter 1,3,5-Triazine. Wissenschaftliche Zeitschrift der Karl-Marx-Universität Leipzig, Math.-Naturwiss. Reihe 31 (4), pp. 313-320.

Angerer, Erwin von (1982) Effect of N,N'-diethyl-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamines on the 7,12-dimethylbenz[a]anthracene-induced mammary carcinoma of the rat. Journal of medicinal chemistry 25 (11), pp. 1374-1377.

Angerer, Erwin von and Egginger, Guenter and Kranzfelder, Gerhard and Bernhauer, Horst and Schönenberger, Helmut (1982) N,N'-Dialkyl-1,2-bis(hydroxyphenyl)ethylenediamines and N,N-dialkyl-4,5-bis(4-hydroxyphenyl)imidazolidines: syntheses and evaluation of their mammary tumor inhibiting activity. Journal of medicinal chemistry 25 (7), pp. 832-837.

Buschauer, Armin and Sattler, Hans-Joachim and Schunack, Walter (1982) Synthese von 2-(2-Aminoethyl)-4-hydroxymethyl-imidazol. Arch. Pharm. (Weinheim) 315, pp. 563-566.

1981

Dove, Stefan and Kühne, R. and Franke, R. (1981) Hauptkomponentenanalyse von Verteilungskoeffizienten. Aus dem wissenschaftlichen Leben der Pädagogischen Hochschule "N. K. Krupskaja" Halle, S. 1/2, pp. 1-8.

Bernhardt, Günther and Rudolph, Rainer and Jaenicke, Rainer (1981) Reassociation of lactic dehydrogenase from pig heart studied by cross-linking with glutaraldehyde. Zeitschrift fuer Naturforschung, C Journal of Biosciences 36C (9-10), pp. 772-777.

Schneider, M. R. and Kranzfelder, G. and Angerer, E. von and Schönenberger, H. and Metzler, M. and Michel, R. T. and Fortmeyer, H. P. and Ruckdeschel, G. (1981) The tumor-inhibiting effect of diethylstilbestrol-3,4-oxide. Journal of cancer research and clinical oncology 100 (3), pp. 247-254.

1980

Hartmann, Rolf W. and Kranzfelder, Gerhard and Angerer, Erwin von and Schönenberger, Helmut (1980) Antiestrogens. Synthesis and evaluation of mammary tumor inhibiting activity of 1,1,2,2-tetraalkyl-1,2 -diphenylethanes. Journal of medicinal chemistry 23 (8), pp. 841-8.

Kranzfelder, G. and Schneider, M. and von Angerer, E. and Schönenberger, H. (1980) Entwicklung neuer Antiostrogene vom Typ des 3,3'-Dihydroxy-alpha, beta-diathylstilbens und ihre Prufung am DMBA-induzierten, hormonabhangigen Mammacarcinom der SD-Ratte. Journal of cancer research and clinical oncology 97 (2), pp. 167-186.

Schneider, Martin and Angerer, Erwin von and Kranzfelder, Gerhard and Schönenberger, Helmut (1980) Mammatumorhemmende Antiöstrogene vom Typ des 3,3'-Dihydroxy-alpha, beta-dialkylstilbens. Archiv der Pharmazie 313 (11), pp. 919-925.

Angerer, E. von and Kranzfelder, G. and Taneja, A. K. and Schönenberger, H. (1980) N,N'-Dialkylbis(dichlorophenyl)ethylenediamines and -imidazolidines: relationship between structure and estradiol receptor affinity. Journal of medicinal chemistry 23 (12), pp. 1347-1350.

Streich, W.-J. and Dove, Stefan and Franke, R. (1980) On the Rational Selection of Test Series. I. Principal Component Analysis Combined with Multidimensional Mapping (PCMM Method). Journal of Medicinal Chemistry 23 (12), pp. 1452-1456.

Dove, Stefan and Streich, J. and Franke, R. (1980) On the Rational Selection of Test Series. II. Two-Dimensional Mapping of Intraclass Correlation Matrices (TMIC Method). Journal of Medicinal Chemistry 23 (12), pp. 1456-1459.

Dove, Stefan and Franke, R. and Kühne, R. (1980) Principal Component Analysis of Partition Coefficients in Different Solvent Systems. In: Knoll, J. and Darvas, F., (eds.) Chemical Structure - Biological Activity Relationships: Quantitative Approaches. Advance in pharmacological research and practice. 3. congress of the Hungarian Pharmacological Soc., 3. Pergamon, Oxford, 247 - 255. ISBN 0080263887; 978-0080263885.

Franke, R. and Barth, A. and Dove, Stefan and Laass, W. (1980) Quantitative Structure-Activity Relationships (QSAR) in Piperidinoacetanilides for Different Biological Effects - Some General Aspects. Pharmazie 35 (3), pp. 181-184.

Franke, R. and Streich, W.-J. and Dove, Stefan (1980) Sample Selection Methods. In: Knoll, J. and Darvas, F., (eds.) Chemical Structure - Biological Actvity Relationships: Quantitative Approaches. ADVANCES IN PHARMACOLOGICAL RESEARCH AND PRACTICE : PROCEEDINGS OF THE 3RD CONGRESS OF THE HUNGARIAN PHARMACOLOGICAL SOCIETY, BUDAPEST, 1979, 3. Akademiai Kiado, Budapest, 153 - 157. ISBN 963-05-2368-X.

Angerer, Erwin von and Taneja, Ashok K. and Ringshandl, Richard and Schönenberger, Helmut (1980) Thermolyse ortho-chlorsubstituierter 1,2-Diarylethylendiamine. Liebigs Annalen der Chemie 1980 (3), pp. 409-415.

1979

Dove, Stefan and Franke, R. and Mndshojan, O. L. and Shkuljev, W. A. and Chashakjan, L. W. (1979) Discriminant-Analytical Investigation on the Structural Dependence of Hyperglycemic and Hypoglycemic Activity in a Series of Substituted ortho-Toluolsulphonylthioureas and ortho-Toluolsulphonylureas. Journal of Medicinal Chemistry 22 (1), pp. 90-95.

Franke, R. and Dove, Stefan and Kühne, R. (1979) Hydrophobicity and Hydrophobic Interactions I. On the Physical Nature of Aromatic Hydrophobic Substituent Constants. European journal of medicinal chemistry 14 (4), pp. 363-372.

Franke, R. and Vasilev, G. N. and Dove, Stefan (1979) Relationships between Structure and Cytotoxicity of Thiourea Derivatives. Doklady Bolgarskoj Akademii Nauk (Sofia) 32 (3), pp. 369-375.

1978

Dove, Stefan (1978) Zur Anwendung einiger multivariater Verfahren auf spezielle Probleme der quantitativen Struktur-Wirkungs-Analyse. PhD, Martin-Luther-Universität Halle.

Dove, Stefan and Franke, R. (1978) Discriminant Analysis and QSAR Work. In: Franke, R. and Oehme, P., (eds.) Quantitative Structure-Activity Analysis / Proceedings of the 2th Symposium on Chemical Structure - Biological Activity Relationships: Quantitative Approaches. Abhandlungen der Akademie der Wisenschaften der DDR, 2N. Akademie-Verlag, Berlin, 257 - 262.

Dove, Stefan and Franke, R. (1978) Einige Probleme beim Einsatz der Hauptkomponentenanalyse in der QSWA. In: Franke, R. and Oehme, P., (eds.) Quantitative Structure-Activity Analysis / Proceedings of the 2th Symposium on Chemical Structure - Biological Activity Relationships: Quantitative Approaches. Abhandlungen der Akademie der Wissenschaften der DDR, 2N. Akademie-Verlag, Berlin, 321 - 326.

Laass, W. and Eichler, G. and Dove, Stefan and Vogt, W. E. and Franke, R. and Vahle, H. (1978) First experience in the use of factor analysis on the choice of variables for regression analysis in QSAR. In: Franke, R. and Oehme, P., (eds.) Quantitative Structure-Activity Analysis / Proceedings of the 2th Symposium on Chemical Structure - Biological Activity Relationships: Quantitative Approaches. Abhandl. der AdW der DDR, 2N. Akademie-Verlag, Berlin, 267 - 271.

Rösner, T. and Dove, Stefan and Schönfelder, D. and Franke, R. and Unger, S. and Jentsch, W. (1978) Use of a complex classification system in pattern recognition problems for the determination of structure-activity relations. In: Franke, R. and Oehme, P., (eds.) Quantitative Structure-Activity Analysis / Proceedings of the 2th Symposium on Chemical Structure - Biological Activity Relationships: Quantitative Approaches. Abhandl. der AdW der DDR, 2N. Akademie-Verlag, Berlin, 273 - 282.

1977

Dove, Stefan and Franke, R. (1977) Möglichkeiten des Einsatzes der Hauptkomponentenanalyse bei der Untersuchung von Struktur-Wirkungs-Beziehungen. Kongreß- und Tagungsberichte der MLU Halle-Wittenberg 18 (N5), pp. 24-30.

Dove, Stefan and Franke, R. (1977) Principal Component Analysis of Time-Dependent Antiinflammatory Activity of a Series of Salicylic Acid Derivatives. Kongreß- und Tagungsberichte der MLU Halle-Wittenberg 42 (R34), pp. 216-224.

Angerer, Erwin von (1977) Synthese und acetolyse des 4-brombenzolsulfonsäure-(7-norbornadienyl)methyl-esters. Tetrahedron Letters 18 (37), pp. 3245-3248.

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