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Dulla, Balakrishna (2014) Synthesis and pharmacological characterization of novel N & O containing heterocyclic compounds as potential therapeutic agents. PhD, Universität Regensburg

Baumeister, Paul (2014) Molecular tools for G-protein coupled receptors:
Synthesis, pharmacological characterization and [3H]-labeling of subtype-selective ligands for histamine H4 and NPY Y2 receptors.
PhD, Universität Regensburg

Hennig, Robert and Pollinger, Klaus and Veser, Anika and Breunig, Miriam and Goepferich, Achim (2014) Nanoparticle multivalency counterbalances the ligand affinity loss upon PEGylation. Journal of Controlled Release 194, pp. 20-27.

Haunschild, Gundula (2014) Nachweis und molekulare Charakterisierung EpCAM-positiver Zellen im Knochenmark von Mammakarzinom-Patientinnen. PhD, Universität Regensburg

Slenczka, Alkwin and Premke, Tobias and Wirths, Eva-Maria and Pentlehner, Dominik and Lehnig, Rudolf and Richers, Ricarda and Vdovin, Alexander (2014) Microsolvation of Molecules in Superfluid Helium Nanodroplets Revealed by Means of Electronic Spectroscopy. Frontiers in Chemistry.

Schramm, Andrea (2014) Analyse renaler Funktionen der cGMP-abhängigen Proteinkinase II. PhD, Universität Regensburg

Tauber, Philipp (2014) Untersuchungen zur Pathogenese von primärem Hyperaldosteronismus in neugeborenen Task3-/- Mäusen und adrenokortikalen Zellen mit KCNJ5-Mutation. PhD, Universität Regensburg

Dove, Stefan (2014) Multivariate analysis of hydrophobic descriptors. ADMET & DMPK 2 (1), pp. 3-17.

Dove, Stefan and Danker, Kerstin Yvonne and Stasch, Johannes-Peter and Kaever, Volkhard and Seifert, Roland (2014) Structure/Activity Relationships of (M)ANT- and TNP-Nucleotides for Inhibition of Rat Soluble Guanylyl Cyclase alpha(1)beta(1). Molecular Pharmacology 85 (4), pp. 598-607.

Rothenhöfer, Martin (2014) Analytical approaches to the study of hyaluronan and hyaluronidases: Development and application of hyphenated chromatographic and electrophoretic methods. PhD, Universität Regensburg

Bücherl, Daniel (2014) Isolation of kaempferol glycosides from Ginkgo biloba leaves and synthesis, identification and quantification of their major in vivo metabolites. PhD, Universität Regensburg

Baumeister, Paul and Erdmann, Daniela and Biselli, Sabrina and Kagermeier, Nicole and Elz, Sigurd and Bernhardt, Günther and Buschauer, Armin (2014) 3HUR-DE257: Development of a tritium-labeled squaramide-type selective histamine H2 receptor antagonist. ChemMedChem. (In Press)

Pollinger, Klaus and Hennig, Robert and Bauer, Stefanie and Breunig, Miriam and Tessmar, Joerg and Buschauer, Armin and Witzgall, Ralph and Göpferich, Achim (2014) Biodistribution of quantum dots in the kidney after intravenous injection. Journal of Nanoscience and Nanotechnology 14 (5), pp. 3313-3319.

Hammer, Nadine and Brandl, Ferdinand and Kirchhof, Susanne and Goepferich, Achim (2014) Cleavable carbamate linkers for controlled protein delivery from hydrogels. Journal of Controlled Release 183, pp. 67-76.

Cuboni, Serena and Devigny, Christian and Hoogeland, Bastiaan and Strasser, Andrea and Pomplun, Sebastian and Hauger, Barbara and Höfner, Georg and Wanner, Klaus and Eder, Matthias and Buschauer, Armin and Holsboer, Florian and Hausch, Felix (2014) Loratadine and analogs: Discovery and preliminary SAR of inhibitors of the amino acid transporter B0AT2. Journal of Medicinal Chemistry. (In Press)

Wittmann, Hans-Joachim and Seifert, Roland and Strasser, Andrea (2014) Mathematical analysis of the sodium sensitivity of the human histamine H3 receptor. In silico pharmacology 2.

Wifling, David and Löffel, Karolin and Nordemann, Uwe and Strasser, Andrea and Bernhardt, Günther and Dove, Stefan and Seifert, Roland and Buschauer, Armin (2014) Molecular determinants for the high constitutive activity of the human histamine H4 receptor: Functional studies on orthologs and mutants. British Journal of Pharmacology. (In Press)

Werner, Kristin and Neumann, Detlef and Buschauer, Armin and Seifert, Roland (2014) No evidence for histamine H4-receptor in human monocytes. Journal of Pharmacology and Experimental Therapeutics. (In Press)

Wager, Eva and Wittmann, Hans-Joachim and Elz, Sigurd and Strasser, Andrea (2014) Pharmacological profile of astemizole-derived compounds at the histamine H1 and H4 receptor - H1/H4 receptor selectivity. Naunyn-Schmiedeberg's Archives of Pharmacology 387, pp. 235-250.

Luschmann, Christoph and Tessmar, Joerg and Schoeberl, Simon and Strauss, O. and Luschmann, Karl and Goepferich, Achim (2014) Self-​assembling colloidal system for the ocular administration of cyclosporine A. Cornea 33 (1), pp. 77-81.

Wittmann, Hans-Joachim and Seifert, Roland and Strasser, Andrea (2014) Sodium binding to hH3R and hH4R - a molecular modelling study. Journal of Molecular Modeling 20, p. 2394.

Geyer, Roland and Kaske, Melanie and Baumeister, Paul and Buschauer, Armin (2014) Synthesis and functional characterization of imbutamine analogs as histamine H3 and H4 receptor ligands. Archiv der Pharmazie (Weinheim, Germany) 347 (2), pp. 77-88.

Geyer, Roland and Igel, Patrick and Kaske, Melanie and Elz, Sigurd and Buschauer, Armin (2014) Synthesis, SAR and selectivity of 2-acyl- and 2-cyano-1-hetarylalkyl-guanidines at the four histamine receptor subtypes: a bioisosteric approach. MedChemComm 5 (1), pp. 72-81.

Darras, Fouad and Pockes, Steffen and Huang, Guozheng and Wehle, Sarah and Strasser, Andrea and Wittmann, Hans-Joachim and Nimczick, Martin and Sotriffer, Christoph and Decker, Michael (2014) Synthesis, biological evaluation, and computational studies of tri- and tetracyclic nitrogen-bridgehead compounds as potent dual-acting AChE inhibitors and hH3 receptor antagonists. ACS Chemical Neuroscience 5, pp. 225-242.

Endlich, Nicole and Simon, Ole and Goepferich, Achim and Wegner, Henny and Moeller, Marcus J. and Rumpel, Elisabeth and Kotb, Ahmed and Endlich, Karlhans (2014) Two-Photon Microscopy Reveals Stationary Podocytes in Living Zebrafish Larvae. Journal of the American Society of Nephrology 25 (4), pp. 681-686.

Schickaneder, Helmut and Buschauer, Armin and Bernhardt, Günther and Schickaneder, Christian and Limmert, Michael and Huber, Stefan and Lubbe, Mathias and Hofmeier, Harald (2013) Esters of bendamustine and related compounds, and medical use thereof.

Brunner, Elisabeth (2013) Einsatz von Everolimus zur Prävention der chronischen Abstoßung nach orthotoper unilateraler Lungentransplantation in der Ratte. PhD, Universität Regensburg

Schmidt, Sebastian (2013) Phytochemische und pharmakologische in vitro Untersuchungen zu Hypericum empetrifolium WILLD. PhD, Universität Regensburg

Loth, Tina and Hennig, Robert and Kascholke, Christian and Hötzel, Rudi and Hacker, Michael (2013) Reactive and stimuli-responsive maleic anhydride containing macromers–multi-functional cross-linkers and building blocks for hydrogel fabrication. Reactive and Functional Polymers 73 (11), pp. 1480-1492.

Sadek, Bassem and Alisch, Rudi and Buschauer, Armin and Elz, Sigurd (2013) Synthesis and dual histamine H1 and H2 receptor antagonist activity of cyanoguanidine derivatives. Molecules 18 (11), pp. 14186-14202.

Dove, Stefan and Buschauer, Armin (2013) G-Protein-gekoppelte Rezeptoren: „Sinnesorgane“ der Zellen. Blick in die Wissenschaft 22 (28), pp. 3-9.

Schreeb, Annemarie and Łażewska, Dorota and Dove, Stefan and Buschauer, Armin and Kieć-Kononiwcz, Katarzyna and Stark, Holger (2013) 2. Histamine H4 receptor ligands. In: Stark, Holger, (ed.) Histamine H4 receptor: a novel drug target for immunoregulation and inflammation. Versita, London, pp. 21-62. ISBN 9788376560564.

Stöckl, Sabine (2013) Der Einfluss von Sox9 auf Zellvitalität und Differenzierungspotential von adulten mesenchymalen Stammzellen. PhD, Universität Regensburg

Keller, Max and Kaske, Melanie and Holzammer, Tobias and Bernhardt, Günther and Buschauer, Armin (2013) Dimeric argininamide-type neuropeptide Y receptor antagonists: chiral discrimination between Y1 and Y4 receptors. Bioorganic and Medicinal Chemistry 21 (21), pp. 6303-6322.

Weisser, Roland (2013) Planung einer Studie zur Etablierung des therapeutischen Referenzbereichs der Wirkstoffkonzentration eines Antidementivums. PhD, Universität Regensburg

Berlicki, Lukasz and Kaske, Melanie and Gutierrez-Abad, Raquel and Bernhardt, Günther and Illa, Ona and Ortuño, Rosa and Cabrele, Chiara and Buschauer, Armin and Reiser, Oliver (2013) Replacement of Thr32 and Gln34 in the C-terminal neuropeptide Y fragment 25-36 by cis-cyclobutane- and cis-cyclopentane β-amino acids shifts selectivity toward the Y4 receptor. Journal of Medicinal Chemistry 56 (21), pp. 8422-8431.

Nordemann, Uwe and Wifling, David and Schnell, David and Bernhardt, Günther and Stark, Holger and Seifert, Roland and Buschauer, Armin (2013) Luciferase reporter gene assay on human, murine and rat histamine H4 receptor orthologs: correlations and discrepancies between distal and proximal readouts. PLoS One 8 (9), e73961.

Bauer, Stefanie and Ochoa Puentes, Cristian and Sun, Qiu and Bause, Manuel and Bernhardt, Günther and König, Burkhard and Buschauer, Armin (2013) Quinoline carboxamide-type ABCG2 modulators: Indole and quinoline moieties as anilide replacements. ChemMedChem 8 (11), pp. 1773-1778.

Holzammer, Tobias (2013) Homology modeling, molecular dynamics simulations and site-directed mutagenesis of histamine H2 receptors. PhD, Universität Regensburg

Kirchhof, Susanne and Brandl, Ferdinand and Hammer, Nadine and Göpferich, Achim (2013) Investigation of the Diels–Alder reaction as a cross-linking mechanism for degradable poly(ethylene glycol) based hydrogels. Journal of Materials Chemistry B 1 (37), pp. 4855-4864.

Kaske, Melanie (2013) In search for potent and selective NPY Y4 receptor ligands: acylguanidines, argininamides and peptide analogs. PhD, Universität Regensburg

Brunskole Hummel, Irena and Kälble, Solveig and Burhenne, Heike and Reinartz, Michael T. and Schwede, Frank and Buschauer, Armin and Seifert, Roland (2013) Dissociations in the effects of beta2-adrenergic receptor agonists on cAMP formation and superoxide production in human neutrophils: Support for the concept of functional selectivity. PLoS One 8 (5), e64556.

Zölls, Sarah and Gregoritza, Manuel and Tantipolphan, Ruedeeporn and Wiggenhorn, Michael and Winter, Gerhard and Friess, Wolfgang and Hawe, Andrea (2013) How Subvisible Particles Become Invisible - Relevance of the Refractive Index for Protein Particle Analysis. Journal of Pharmaceutical Sciences 102 (5), pp. 1434-1446.

Kees, Martin Georg and Schaeftlein, André and Haeberle, Helene Anna and Kees, Frieder K. and Kloft, Charlotte and Heininger, Alexandra (2013) Population pharmacokinetics and pharmacodynamic evaluation of intravenous and enteral moxifloxacin in surgical intensive care unit patients. The Journal of antimicrobial chemotherapy.

Ochoa-Puentes, Cristian and Bauer, Stefanie and Kühnle, Matthias and Bernhardt, Günther and Buschauer, Armin and König, Burkhard (2013) Benzanilide – Biphenyl Replacement: A Bioisosteric Approach to Quinoline Carboxamide-type ABCG2 Modulators. ACS Medicinal Chemistry Letters 4 (4), pp. 393-396.

Pluym, Nikola and Baumeister, Paul and Keller, Max and Bernhardt, Günther and Buschauer, Armin (2013) [3H]UR-PLN196: A Selective Nonpeptide Radioligand and Insurmountable Antagonist for the Neuropeptide Y Y2 Receptor. ChemMedChem 8 (4), pp. 587-593.

Miller, Tobias (2013) Polymeric micelles for solubilization and targeting of hydrophobic drugs. PhD, Universität Regensburg

Seifert, Roland and Strasser, Andrea and Schneider, Erich H. and Neumann, Detlef and Dove, Stefan and Buschauer, Armin (2013) Molecular and cellular analysis of human histamine receptor subtypes. Trends in Pharmacological Sciences 34 (1), pp. 33-58.

Strasser, Andrea and Wittmann, Hans-Joachim and Buschauer, Armin and Schneider, Erich H. and Seifert, Roland (2013) Species-dependent activities of GPCR ligands: Lessons from histamine receptor orthologs. Trends in Pharmacological Sciences 34 (1), pp. 13-32.

Luschmann, Christoph and Tessmar, Joerg and Schoeberl, Simon and Framme, Carsten and Luschmann, Karl and Goepferich, Achim (2013) Developing an in situ nanosuspension: A novel approach towards the efficient administration of poorly soluble drugs at the anterior eye. European Journal of Pharmaceutical Sciences 50 (3-4), pp. 385-392.

Miller, Tobias and van Colen, G. and Sander, B. and Golas, M. and Uezguen, Senta and Weigandt, Markus and Goepferich, Achim (2013) Drug Loading of Polymerics Micelles. Pharmaceutical Research 30 (2), pp. 484-595.

Dietrich, P. and Moleda, Lukas and Kees, Frieder K. and Müller, M. and Straub, R. H. and Hellerbrand, C. and Wiest, R. (2013) Dysbalance in sympathetic neurotransmitter release and action in cirrhotic rats: impact of exogenous neuropeptide Y. Journal of hepatology 58 (2), pp. 254-261.

Ferstl, Matthias and Drechsler, Markus and Rachel, Reinhard and Rischer, M. and Engel, J. and Backofen, Michael and Goepferich, Achim (2013) Impact of Polyelectrolyte Structure on the Shape of Nanoassemblies with Cationic Peptides. European Journal of Pharmaceutical Sciences 102, pp. 2599-2607.

Seifert, Roland and Dove, Stefan (2013) Inhibitors of Bacillus anthracis edema factor. Pharmacology & Therapeutics 140 (2), pp. 200-212.

Mueller, M. and Blunk, Torsten and Appel, Bernhard and Maschke, Angelika and Goepferich, Achim and Zellner, J. (2013) Insulin is essential for in vitro chondrogenesis of mesenchymal progenitor cells and influences chondrogenesis in a dose-dependent manner. International orthopaedics 37 (1), pp. 153-158.

Wurster, Eva-Christina and Elbakry, Asmaa and Goepferich, Achim and Breunig, Miriam (2013) Layer-by-layer assembled gold nanoparticles for the delivery of nucleic acids. In: Nanotechnology for Nucleic Acid Delivery : Methods and Protocols. Methods in Molecular Biology, 948. Humana Press; Springer, Totowa, NJ, pp. 171-182. ISBN 978-1-62703-139-4 (print), 978-1-627-03140-0 (online).

Pollinger, Klaus and Hennig, Robert and Ohlmann, Andreas and Fuchshofer, R. and Wenzel, Rebecca and Breunig, Miriam (2013) Ligand-functionalized nanoparticles target endothelial cells in retinal capillaries after systemic application. Proceedings of the National Academy of Sciences of the United States of America (PNAS) 25, pp. 6115-6120.

Strasser, Andrea and Wittmann, Hans-Joachim (2013) Modelling of GPCRs - A Practical Handbook. Springer.

Strasser, Andrea and Wittmann, Hans-Joachim (2013) Molecular modelling studies give hint for the existence of a symmetric hb2R-Gabg-homodimer. J Mol Model 19, pp. 4443-4457.

Hozsa, Constantin and Breunig, Miriam and Goepferich, Achim (2013) Monitoring the Degradation of Reduction-Sensitive Gene Carriers with Fluorescence Spectroscopy and Flow Cytometry. Methods in Molecular Biology 991, pp. 171-184.

Luschmann, Christoph and Herrmann, W. and Strauss, Olaf and Luschmann, Karl and Goepferich, Achim (2013) Ocular delivery systems for poorly soluble drugs: An in-vivo evaluation. International Journal of Pharmaceutics 455 (1-2), pp. 331-337.

Schweizer, Daniel and Voitier, I. and Heier, A. and Serno, Tim and Goepferich, Achim and et , al. (2013) Pharmacokinetics, biocompatibility and bioavailability of a controlled release monoclonal antibody formulation. Journal of Controlled Release 172 (3), pp. 975-982.

Miller, Tobias and Breyer, S. and van Colen, G. and Mier, W. and Haberkorn, U. and Geissler, S. and Voss, S. and Weigandt, Markus and Goepferich, Achim (2013) Premature drug release of polymeric micelles and its effects on tumor targeting. International Journal of Pharmaceutics 445 (1-2), pp. 117-124.

Holzhauser, C. and Liebl, Renate and Goepferich, Achim and Wagenknecht, Hans-Achim and Breunig, Miriam (2013) RNA “Traffic Lights”: An Analytical Tool to Monitor siRNA Integrity. ACS chemical biology 8, pp. 890-894.

Nordemann, Uwe (2013) Radioligand binding and reporter gene assays for histamine H3 and H4 receptor species orthologs. PhD, Universität Regensburg

Bodensteiner, Julian and Baumeister, Paul and Geyer, Roland and Buschauer, Armin and Reiser, Oliver (2013) Synthesis and pharmacological characterization of new tetrahydrofuran based compounds as conformationally constrained histamine receptor ligands. Organic & biomolecular chemistry 11 (24), pp. 4040-55.

Göpferich, Achim (2013) To pause a moment. European Journal of Pharmaceutics and Biopharmaceutics 85 (3), p. 328.

Wolfertstetter, Stefanie and Huettner, Johannes Philip and Schlossmann, Jens (2013) cGMP-dependent Protein Kinase Inhibitors in Health and Disease. Pharmaceuticals 6, pp. 269-286.

Ertel, Miriam and Bernhardt, Günther and Nink, Jörg and Buschauer, Armin (2012) Novel prodrugs of (1S,9S)-9-[[(1S)-1-carboxy-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid and their use in transdermal therapeutic systems.

Memminger, Martin and Keller, Max and Lopuch, Miroslaw and Pop, Nathalie and Bernhardt, Günther and von Angerer, Erwin and Buschauer, Armin (2012) The Neuropeptide Y Y1 receptor: a diagnostic marker? Expression in MCF-7 breast cancer cells is down-regulated by antiestrogens in vitro and in xenografts. PLoS ONE 7 (12), e51032.

Löber, Stefan and Hübner, Harald and Buschauer, Armin and Sanna, Fabrizio and Argiolas, Antonio and Melis, Maria Rosaria and Gmeiner, Peter (2012) Novel azulene derivatives for the treatment of erectile dysfunction. Bioorganic & medicinal chemistry letters 22 (23), pp. 7151-7154.

Saugspier, Michael Sebastian (2012) Analysis of the anti-fibrotic effects of hop bitter acids on hepatic stellate cells and their anti-tumorigenic effects on hepatocellular carcinoma cells. PhD, Universität Regensburg

Rothenhöfer, Martin and Scherübl, Rosmarie and Bernhardt, Günther and Heilmann, Jörg and Buschauer, Armin (2012) Qualitative and quantitative analysis of hyaluronan oligosaccharides with high performance thin layer chromatography using reagent-free derivatization on amino-modified silica and electrospray ionization-quadrupole time-of-flight mass spectrometry coupling on normal phase. Journal of chromatography. A 1248, pp. 169-77.

Ertel, Miriam (2012) Ambivalence of drug metabolism: Exploration of cilazapril and candesartan prodrugs for transdermal delivery and search for toxic reactive intermediates of N(G)-acylated hetarylpropylguanidines. PhD, Universität Regensburg

Hild, Wolfgang (2012) Cellular nanoparticle delivery by G-protein coupled receptors. PhD, Universität Regensburg

Reher, Till M. and Neumann, Detlef and Buschauer, Armin and Seifert, Roland (2012) Incomplete activation of human eosinophils via the histamine H(4)-receptor: Evidence for ligand-specific receptor conformations. Biochemical Pharmacology 84 (2), pp. 192-203.

Seifert, Roland and Dove, Stefan (2012) 3/14. Molecular analysis of agonist stereoisomers at β2-adrenoceptors. In: Jozwiak , Krzysztof and Lough, W. John and Wainer, Irving W., (eds.) Drug stereochemistry : Analytical methods and pharmacology. 3. ed. Informa Healthcare, New York, pp. 274-293. ISBN 9781420092387.

Deml, Karl-Friedrich (2012) Interaktionen von Histamin H1-Rezeptoragonisten und
–antagonisten mit dem humanen Histamin H4-Rezeptor.
PhD, Universität Regensburg

Birnkammer, Tobias and Spickenreither, Anja and Brunskole, Irena and Lopuch, Miroslaw and Kagermeier, Nicole and Bernhardt, Günther and Dove, Stefan and Seifert, Roland and Elz, Sigurd and Buschauer, Armin (2012) The bivalent ligand approach leads to highly potent and selective acylguanidine-type histamine H2 receptor agonists. Journal of Medicinal Chemistry 55 (3), pp. 1147-1160.

Bauhuber, Sonja and Liebl, Renate and Tomasetti, Luise and Rachel, Reinhard and Goepferich, Achim and Breunig, Miriam (2012) A library of strictly linear poly(ethylene glycol)-poly(ethylene imine) diblock coploymers to perform structure-function relationship on non-viral gene carriers. Journal of Controlled Release 162, pp. 446-455.

Miller, Tobias and Hiller, Alexandra and Uezguen, Senta and Weigandt, Markus and Goepferich, Achim (2012) Analysis of Immediate Stress Mechanisms upon Injection of Polymeric Micelles and Related Colloidal Drug Carriers. Biomacromolecules 13 (6), pp. 1707-1718.

Miller, Tobias and Rachel, Reinhard and Besheer, Ahmed and Uezguen, Senta and Weigand, Markus and Göpferich, Achim (2012) Comparative Investigations on In Vitro Serum Stability of Polymeric Micelle Formulations. Pharmaceutical Research 29 (2), pp. 448-459.

Posavec, Damir and Zabel, Manfred and Bogner, Udo and Bernhardt, Günther and Knör, Günther (2012) Functionalized derivatives of 1,4-dimethylnaphthalene as precursors for biomedical applications: synthesis, structures, spectroscopy and photochemical activation in the presence of dioxygen. Organic & biomolecular chemistry 10 (35), pp. 7062-7069.

Appl, Heidrun and Holzammer, Tobias and Dove, Stefan and Haen, Ekkehard and Strasser, Andrea and Seifert, Roland (2012) Interactions of recombinant human histamine H₁R, H₂R, H₃R, and H₄R receptors with 34 antidepressants and antipsychotics. Naunyn-Schmiedeberg's archives of pharmacology 385 (2), pp. 145-170.

Pollinger, Klaus and Hennig, Robert and Breunig, Miriam and Teßmar, Jörg and Ohlmann, Andreas and Tamm, Ernst R. and Witzgall, Ralph and Goepferich, Achim (2012) Kidney Podocytes as Specific Targets for cyclo(RGDfC)-Modified Nanoparticles. Small 8, pp. 3368-3375.

Elbakry, Asmaa Mohamed and Wurster, Eva-Christina and Zaky, Alaa and Liebl, Renate and Schindler, Edith and Bauer-Kreisel, Petra and Blunk, Torsten and Rachel, Reinhard and Goepferich, Achim and Breunig, Miriam (2012) Layer-by-Layer Coated Gold Nanoparticles: Size-Dependent Delivery of DNA into Cells. Small 8 (24), pp. 3847-3856.

Heller, Anne and Fischer, Lorenz H. and Wolfbeis, Otto S. and Göpferich, Achim (2012) Long time monitoring of the respiratory activity of isolated mitochondria. Experimental Cell Research 318 (14), pp. 1667-1672.

Kees, Martin G. and Steinke, T. and Moritz, S. and Rupprecht, K. and Paulus, E. M. and Kees, Frieder K. and Bucher, M. and Faerber, L. (2012) Omeprazole impairs the absorption of mycophenolate mofetil but not of enteric-coated mycophenolate sodium in healthy volunteers. Journal of clinical pharmacology 52 (8), pp. 1265-1272.

Justinger, Christoph and Schilling, Martin K. and Kees, Martin G. and Kauffels, Anne and Hirschmann, Katrin and Kopp, Berit and Kees, Frieder K. and Kollmar, Otto (2012) Penetration of moxifloxacin into liver tissue. International journal of antimicrobial agents 39 (6), pp. 505-509.

Bernat, Viachaslau and Heinrich, Markus and Baumeister, Paul and Buschauer, Armin and Tschammer, Nuska (2012) Synthesis and application of the first radioligand targeting the allosteric binding pocket of chemokine receptor CXCR3. ChemMedChem 7 (8), pp. 1481-1489.

Heller, Anne and Brockhoff, Gero and Goepferich, Achim (2012) Targeting drugs to mitochondria. European Journal of Pharmaceutics and Biopharmaceutics 82, pp. 1-18.

Seifert, Roland and Dove, Stefan (2012) Towards selective inhibitors of adenylyl cyclase toxin from Bordetella pertussis. Trends in microbiology 20 (7), pp. 343-351.

Kaftan, Holger and Goepferich, Achim and Kaftan, Silke and Hosemann, Werner (2012) Two different techniques to facilitate reconstruction of the long incus process with bone cement: a feasibility study in human cadaveric temporal bones. European Archives of Oto-Rhino-Laryngology 269, pp. 1431-1435.

Strasser, Andrea and Wittmann, Hans-Joachim (2012) hb2R-Gas-complex: Prediction versus crystal structure - How valuable are predictions based on molecular modelling studies? Journal of Molecular Modeling : J Mol Model 18, pp. 3439-3444.

Brunskole, Irena (2011) Molecular and cellular analysis of aminergic G protein-coupled receptors: histamine H2, H4 and β2-adrenergic receptors, a scientific paradigm. PhD, Universität Regensburg

Geyer, Roland (2011) Hetarylalkyl(aryl)cyanoguanidines as histamine H4 receptor ligands: Synthesis, chiral separation, pharmacological characterization, structure-activity and -selectivity relationships. PhD, Universität Regensburg

Lopuch, Miroslaw (2011) Investigations on neuropeptide Y and histamine receptors by fluorescence-based and radiochemical methods. PhD, Universität Regensburg

Erdorf, Miriam and Seifert, Roland (2011) Pharmacological characterization of adenylyl cyclase isoforms in rabbit kidney membranes. Naunyn-Schmiedeberg's Archives of Pharmacology 383 (4), pp. 357-372.

Kellermann, K. and Dertinger, N. and Blobner, M. and Kees, Frieder and Kochs, E. F. and Jungwirt, B. (2011) Perioperative moxifloxacin treatment in rats subjected to deep hypothermic circulatory arrest: reduction in cerebral inflammation but without improvement in cognitive performance. Journal of Thoracic and Cardiovascular Surgery 141 (3), pp. 796-802.

Schinner, Elisabeth and Salb, Katharina and Schlossmann, Jens (2011) Signaling via IRAG is essential for NO/cGMP-dependent inhibition of platelet activitation. Platelets.

Osman, Shaaban and Brandl, Ferdinand and Zayed, Gamal and Teßmar, Jörg and Göpferich, Achim (2011) Cyclodextrin based hydrogels: Inclusion complex formation and micellization of adamantane and cholesterol grafted polymers. Polymer 52 (21), pp. 4806-4812.

Schaedlich, A. and Rose, C. and Kuntsche, J. and Caysa , H. and Mueller, T. and Goepferich, Achim and Maeder, K. (2011) How Stealthy are PEG-PLA Nanoparticles? An NIR In Vivo Study Combined with Detailed Size Measurements. Pharmaceutical Research 28 (8), pp. 1995-2007.

Wittmann, Hans-Joachim and Seifert, Roland and Strasser, Andrea (2011) Influence of the N-terminus and the E2-loop onto the binding kinetics of the antagonist mepyramine and the partial agonist phenoprodifen to H1R. Biochemical Pharmacology 12, pp. 1910-1918.

Wagner, Eva and Wittmann, Hans-Joachim and Elz, Sigurd and Strasser, Andrea (2011) Mepyramine-JNJ7777120-hybrid compounds show high affinity to hH1R, but low affinity to hH4R. Bioorganic & Medicinal Chemistry Letters 21, pp. 6274-9280.

Wittmann, Hans-Joachim and Elz, Sigurd and Seifert, Roland and Strasser, Andrea (2011) Na-methylated phenylhistamines exhibit affinity to the hH4R - a pharmacological and molecular modelling study. Naunyn Schmiedeberg's Arch Pharmacol 384, pp. 287-299.

Ferstl, Matthias and Strasser, Andrea and Wittmann, Hans-Joachim and Drechsler, Markus and Rischer, M. and Engl, J. and Goepferich, Achim (2011) Nanofibres Resulating from Cooperative Electrostatic and Hydrophobic Interactions between Peptides and Polyelectrolytes of Opposite Charge. Langmuir 27, pp. 14450-14459.

Kees, Martin G. and Weber, Susanne and Kees, Frieder K. and Horbach, Thomas (2011) Pharmacokinetics of moxifloxacin in plasma and tissue of morbidly obese patients. The Journal of antimicrobial chemotherapy 66 (10), pp. 2330-2335.

Schaedlich, A. and Caysa , H. and Mueller, T. and Tenambergen, F and Rose, Cornelia and Goepferich, Achim and Kuntsche, J. and Maeder, K. (2011) Tumor Accumulation of NIR Fluorescent PEG PLA Nanoparticles: Impact of Particle Size and Human Xenograft Tumor Model. ACS Nano 5, pp. 8710-8720.

Kees, MG and Hilpert, JW and Gnewuch, C and Kees, F. and Voegeler, S. (2010) Clearance of vancomycin during continuous infusion in intensive care unit patients: correlation with measured and estimated creatinine clearance and serum cystatin C. International Journal of Antimicrobial Agents 36 (6), pp. 545-548.

Schnell, David and Strasser, Andrea and Seifert, Roland (2010) Comparison of the pharmacological properties of human and rat histamine H(3)-receptors. Biochemical Pharmacology 80 (9), pp. 1437-1449.

Mathar, I. and Vennekens, R. and Meissner, M. and Kees, Frieder K. and Van der Mieren , G. and Camacho Londono, J. (2010) Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice. The Journal of Clinical Investigation 120 (9), pp. 3267-3279.

Desch, Matthias and Schinner, Elisabeth and Kees, Frieder K. and Hofmann, F. and Seifert, Roland and Schlossmann, Jens (2010) Cyclic cytidine 3´,5´-monophosphate (cCMP) signals via cGMP kinase I. FEBS Letters 584 (18), pp. 3979-3984.

Schneider, E. H. and Strasser, Andrea and Thurmond, R. L. and Seifert, Roland (2010) Structural requirements for inverse agonism and neutral antagonism of indole-, benzimidazole-, and thienopyrrole-derived histamine H4 receptor ligands. Journal of Pharmacology and Experimental Therapeutics 334 (2), pp. 513-521.

Hild, Wolfgang and Pollinger, Klaus and Caporale, Andrea and Cabrele, Chiara and Keller, Max and Pluym, Nicola and Buschauer, Armin and Rachel, Reinhard and Tessmar, Joerg and Breunig, Miriam and Goepferich, Achim (2010) G protein-coupled receptors function as logic gates for nanoparticle binding and cell uptake. Proceedings of the National Academy of Sciences USA: PNAS 107 (23), pp. 10667-10672.

Desch, Matthias and Sigl, K. and Hieke, Bernhard and Salb, Katharina and Kees, F. and Bernhard, D. (2010) IRAG determines nitric oxide- and atrial natriuretic peptide-mediated smooth muscle relaxation. Cardiovascular Research 86 (3), pp. 496-505.

Schnell, David and Seifert, Roland (2010) Modulation of Histamine H(3) receptor function by monovalent ions. Neuroscience Letters 472 (2), pp. 114-118.

Schnell, David and Burleigh, Katrina and Seifert, Roland and Trick, Jonathan (2010) No evidence for functional selectivity of proxyfan at the human histamine H3 receptor coupled to defined Gi/Go protein heterotrimers. Journal of Pharmacology and Experimental Therapeutics . JPET 332 (3), pp. 996-1005.

Strasser, Andrea and Wittmann , Hans-Joachim (2010) 3D-QSAR CoMFA study to predict orientation of suprahistaprodifens and phenoprodifens in the binding-pocket of four histamine H1-receptor species. Molecular Informatics 29, pp. 333-341.

Schoenhammer, K. and Boisclair, J. and Schuetz, H. and Petersen, H. and Göpferich, Achim (2010) Biocompatibility of an injectable in situ forming depot for peptide delivery. European Journal of Pharmaceutical Sciences 99 (10), pp. 4390-4399.

Brandl, Ferdinand and Hammer, Nadine and Blunk, Torsten and Teßmar, Jörg and Göpferich, Achim (2010) Biodegradable hydrogels for time-controlled release of tethered peptides or proteins. Biomacromolecules 11 (2), pp. 496-504.

Bauer-Kreisel, Petra and Göpferich, Achim and Blunk, Torsten (2010) Cell-delivery therapeutics for adipose tissue regeneration. Advanced Drug Delivery Reviews 62 (7-8), pp. 798-813.

Strasser, Andrea and Wittmann, Hans-Joachim (2010) Distinct interactions between the human adrenergic b2 receptor and Gas - an in silico study. J Mol Model 16, pp. 1307-1318.

Brandl, Ferdinand and Seitz, Anna Katharina and Teßmar, Jörg and Blunk, Torsten and Göpferich, Achim (2010) Enzymatically degradable poly(ethylene glycol) based hydrogels for adipose tissue engineering. Biomaterials 31 (14), pp. 3957-3966.

Brandl, Ferdinand and Kastner, Fritz and Gschwind, R. M. and Blunk, Torsten and Teßmar, Jörg and Göpferich, Achim (2010) Hydrogel-based drug delivery systems: Comparison of drug diffusivity and release kinetics. Journal of Controlled Release 142 (2), pp. 221-228.

Berndl, Sina and Breunig, Miriam and Göpferich, Achim and Wagenknecht, Hans-Achim (2010) Imaging of RNA delivery to cells by thiazole orange as a fluorescent RNA base substitution. Organic & Biomolecular Chemistry 8 (5), pp. 997-999.

Schneider, Erich and Schnell, David and Strasser, Andrea and Dove, Stefan and Seifert, Roland (2010) Impact of the DRY motif and the missing "ionic lock" on constitutive activity and G-protein coupling of the human histamine H4 receptor. J Pharmacol Exp Ther : The journal of pharmacology and experimental therapeutics 333 (2), pp. 382-392.

Strasser, Andrea and Wittmann, Hans-Joachim (2010) In silico analysis of the histaprodifen induced pathway of the guinea-pig histamine H1 receptor. Journal of computer- aided molecular design : J Comput Aided Mol Des 24, pp. 759-769.

Henke, Matthias and Brandl, Ferdinand and Göpferich, Achim and Teßmar, Jörg (2010) Size-dependent release of fluorescent macromolecules and nanoparticles from radically cross-linked hydrogels. European Journal of Pharmaceutics and Biopharmaceutics 74 (2), pp. 184-192.

Holzhauser, C. and Berndl, Sina and Menacher, Florian and Breunig, Miriam and Göpferich, Achim and Wagenknecht, Hans-Achim (2010) Synthesis and Optical Properties of Cyanine Dyes as Fluorescent DNA Base Substitutions for Live Cell Imaging. European Journal of Organic Chemistry (7), pp. 1239-1248.

Zaky, A. and Elbakry, Asmaa and Ehmer, Axel and Breunig, Miriam and Göpferich, Achim (2010) The mechanism of protein release from triglyceride microspheres. Journal of Controlled Release 147 (2), pp. 202-210.

Göpferich, Achim and Rothschenk, Stefan (2009) Cross-linked polymer matrix, in particular for administering protein drugs into the eye. DE102008016998.

Schoenhammer, K. and Petersen, H. and Guethlein, F. and Göpferich, Achim (2009) Poly(ethylene-glycol) 500 Dimethylether as Novel Solvent for Injectable In Situ Forming Depots. Pharmaceutical Research 26 (12), pp. 2568-2577.

Weiser, Barbara and Sommer, Florian and Neubauer, M. and Seitz, Anna Katharina and Teßmar, Jörg and Göpferich, Achim and Blunk, Torsten (2009) Ascorbic Acid Enhances Adipogenesis of Bone Marrow-Derived Mesenchymal Stromal Cells. Cells Tissues Organs 189 (6), pp. 373-381.

Wittmann, Hans-Joachim and Seifert, Roland and Strasser, Andrea (2009) Contribution of binding enthalpy and entropy to affinity of antagonist and agonist binding at human and guinea pig histamine H1-receptor. Molecular Pharmacology 76, pp. 25-37.

Bauhuber, Sonja and Hozsa, Constantin and Breunig, Miriam and Göpferich, Achim (2009) Delivery of Nucleic Acids via Disulfide-Based Carrier Systems. Advanced Materials (Weinheim, Germany) 21 (32-33), pp. 3286-3306.

Beule, A.G. and Steinmeier, E. and Kaftan, H and Biebler, K.-E. and Göpferich, Achim and Wolf, Eva and Hosemann, W. (2009) Effects of a dexamethasone-releasing stent on osteoneogenesis in a rabbit model. American journal of rhinology & allergy 23 (4), pp. 433-436.

Schuessele, Andrea and Mayr, H. and Teßmar, Jörg and Göpferich, Achim (2009) Enhanced BMP-2 performance on hydroxyapatite ceramic surfaces. Journal of Biomedical Materials Research Part A 90A (4), pp. 959-971.

Sommer, Florian and Brandl, Ferdinand and Weiser, Barbara and Teßmar, Jörg and Blunk, Torsten and Göpferich, Achim (2009) FACS as useful tool to study distinct hyalocyte populations. Experimental Eye Research 88 (5), pp. 995-999.

Schoenhammer, K. and Petersen, H. and Guethlein, F. and Göpferich, Achim (2009) Injectable in situ forming depot systems: PEG-DAE as novel solvent for improved PLGA storage stability. International Journal of Pharmaceutics 371 (1-2), pp. 33-39.

Deml, Karl-Friedrich and Beermann , S and Neumann, Detlef and Strasser, Andrea and Seifert, Roland (2009) Interactions of histamine H1-receptor agonists and antagonists with the human histamine H4-receptor. Mol Pharmacol : Molecular pharmacology 76 (5), pp. 1019-1030.

Elbakry, Asmaa and Zaky, A. and Liebl, Renate and Rachel, Reinhard and Göpferich, Achim and Breunig, Miriam (2009) Layer-by-Layer Assembled Gold Nanoparticles for siRNA Delivery. Nano Letters 9 (5), pp. 2059-2064.

Strasser, Andrea (2009) Molecular Modelling and QSAR-based design of histamine receptor ligands. Expert Opinion on Drug Discovery (4), pp. 1061-1075.

Appel, Bernhard and Baumer, Julia and Eyrich, Daniela and Sarhan, Hatem and Taso, S. and Englert, Carsten and Göpferich, Achim (2009) Synergistic effects of growth and differentiation factor-5 (GDF-5) and insulin on expanded chondrocytes in a 3-D environment. Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 17 (11), pp. 1503-1512.

Koelwel, C. and Rothschenk, Stefan and Fuchs-Koelwel, B. and Gabler, B. and Lohmann, C. and Göpferich, Achim (2008) Alginate inserts loaded with epidermal growth factor for the treatment of keratoconjunctivitis sicca. Pharmaceutical Development and Technology 13 (3), pp. 221-231.

Beule, A.G. and Scharf, C. and Biebler, K.-E. and Göpferich, Achim and Steinmeier, E. and Wolf, E. and Hosemann, W. and Kaftan, H. (2008) Effects of Topically Applied Dexamethasone on Mucosal Wound Healing Using a Drug-Releasing Stent. The Laryngoscope 118 (11), pp. 2073-2077.

Sommer, Florian and Pollinger, Klaus and Brandl, Ferdinand and Weiser, Barbara and Teßmar, Jörg and Blunk, Torsten and Göpferich, Achim (2008) Hyalocyte proliferation and ECM accumulation modulated by bFGF and TGF-β1. Graefe's Archive for Clinical and Experimental Ophthalmology 246 (9), pp. 1275-1284.

Weiser, Barbara and Prantl, Lukas and Schubert, Thomas E. O. and Zellner, J. and Fischbach-Teschl, Claudia and Spruss, Thilo and Seitz, Anna Katharina and Teßmar, Jörg and Göpferich, Achim and Blunk, Torsten (2008) In Vivo Development and Long-Term Survival of Engineered Adipose Tissue Depend on In Vitro Precultivation Strategy. Tissue Engineering Part A 14 (2), pp. 275-284.

Göpferich, Achim (2008) Interactive polymers for pharmaceutical and biomedical applications. European journal of pharmaceutics and biopharmaceutics 68 (1), p. 1.

Breunig, Miriam and Hosza, C. and Lungwitz, Uta and Watanabe, K. and Umeda, I. and Kato, H. and Göpferich, Achim (2008) Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: Disulfide bonds boost intracellular release of the cargo. Journal of Controlled Release 130 (1), pp. 57-63.

Lungwitz, Uta and Breunig, Miriam and Liebl, Renate and Blunk, Torsten and Göpferich, Achim (2008) Methoxy poly(ethylene glycol) – Low molecular weight linear polyethylenimine-derived copolymers enable polyplex shielding. European Journal of Pharmaceutics and Biopharmaceutics 69 (1), pp. 134-148.

Preuss, Hendrik and Ghorai, Prasanta and Kraus, Anja and Dove, Stefan and Buschauer, Armin and Seifert, Roland (2007) Point Mutations in the Second Extracellular Loop of the Histamine H2 Receptor do not affect the Species-Selective Activity of Guanidine-Type Agonists. Naunyn Schmiedebergs Arch. Pharmacol. 376 (4), pp. 253-264.

Klinker, J. F. and Schwaner, I. and Offermanns, S. and Hagelüken, A. and Seifert, Roland (1994) Differential activation of dibutyryl cAMP-differentiated HL-60 human leukemia cells by chemoattractants. Biochemical pharmacology 48 (10), pp. 1857-1864.

Wenzel-Seifert, K. and Schächtele, C. and Hummel, R. and Grünbaum, L. and Seifert, Roland (1994) Evidence that inhibition of phorbol ester-induced superoxide anion formation by cyclosporin A in phagocytes is not mediated by direct inhibition of protein kinase C. Biochemical pharmacology 48 (5), pp. 859-864.

Seifert, Roland and Grünbaum, L. and Schultz, Günter (1994) Histamine H1-receptors in HL-60 monocytes are coupled to Gi-proteins and pertussis toxin-insensitive G-proteins and mediate activation of Ca2+ influx without concomitant Ca2+ mobilization from intracellular stores. Naunyn-Schmiedeberg's archives of pharmacology 349 (4), pp. 355-361.

Musgrave, I. F. and Seifert, Roland (1994) Human neutrophils and HL-60 cells do not possess alpha 2-adrenoceptors. Biochemical pharmacology 47 (2), pp. 233-239.

Hagelüken, A. and Grünbaum, L. and Nürnberg, B. and Harhammer, R. and Schunack, W. and Seifert, Roland (1994) Lipophilic beta-adrenoceptor antagonists and local anesthetics are effective direct activators of G-proteins. Biochemical pharmacology 47 (10), pp. 1789-1795.

Musgrave, I. F. and Seifert, Roland and Schultz, Günter (1994) Maitotoxin activates cation channels distinct from the receptor-activated non-selective cation channels of HL-60 cells. The Biochemical journal 301 ( Pt 2, pp. 437-441.

Klinker, J. F. and Hagelüken, A. and Grünbaum, L. and Heilmann, I. and Nürnberg, B. and Harhammer, R. and Offermanns, S. and Schwaner, I. and Ervens, J and Wenzel-Seifert, K and Müller, T. and Seifert, Roland (1994) Mastoparan may activate GTP hydrolysis by Gi-proteins in HL-60 membranes indirectly through interaction with nucleoside diphosphate kinase. The Biochemical journal 304 ( Pt 2, pp. 377-383.

Wenzel-Seifert, K. and Schächtele, C. and Seifert, Roland (1994) N-protein kinase C isoenzymes may be involved in the regulation of various neutrophil functions. Biochemical and biophysical research communications 200 (3), pp. 1536-1543.

Blunk, Torsten (1994) Plasmaproteinadsorption auf kolloidalen Arzneistoffträgern. Analytik, Korrelation mit Oberflächeneigenschaften, Implikationen für das Drug Targeting. PhD, Kiel, Univ..

Naim, M. and Seifert, Roland and Nürnberg, B. and Grünbaum, L. and Schultz, Günter (1994) Some taste substances are direct activators of G-proteins. The Biochemical journal 297 ( Pt 3, pp. 451-454.

Berger, M. and Offermanns, S. and Seifert, Roland and Schultz, Günter (1994) Synthetic lipopeptide Pam3CysSer(Lys)4 is an effective activator of human platelets. The American journal of physiology 266 (6 Pt 1), C1684-C1691.

Seifert, Roland and Hagelüken, A. and Höer, A. and Höer, D. and Grünbaum, L. and Offermanns, S. and Schwaner, I. and Zingel, V. and Schunack, W. and Schultz, Günter (1994) The H1 receptor agonist 2-(3-chlorophenyl)histamine activates Gi proteins in HL-60 cells through a mechanism that is independent of known histamine receptor subtypes. Molecular Pharmacology 45 (4), pp. 578-586.

Tsang, K. W. and Roberts, P. and Read, R. C. and Kees, Frieder and Wilson, R. and Cole, P. J. (1994) The concentrations of clarithromycin and its 14-hydroxy metabolite in sputum of patients with bronchiectasis following single dose oral administration. The Journal of antimicrobial chemotherapy 33 (2), pp. 289-297.

Honeybourne, D. and Kees, Frieder K. and Andrews, J. M. and Baldwin, D. and Wise, R. (1994) The levels of clarithromycin and its 14-hydroxy metabolite in the lung. The European respiratory journal 7 (7), pp. 1275-1280.

Blunk, Torsten and Mak, E. and Müller, R. H. (1993) Characterization of Colloidal Drug Carriers. Die pharmazeutische Industrie : pharmind 55 (6), pp. 612-615.

Sedlmayr, T. and Petersen, F. and Raasch, W. and Kees, Frieder K. (1993) Clarithromycin, ein neues Makrolid-Antibiotikum. Wirksamkeit bei puerperalen Infektionen und Übertritt in die Muttermilch [Clarithromycin, a new macrolide antibiotic. Effectiveness in puerperal infections and pharmacokinetics in breast milk]. Geburtshilfe und Frauenheilkunde 53 (7), pp. 488-491.

Blunk, Torsten and Hochstrasser, D. F. and Sanchez, J. C. and Müller, B. W. and Müller, R. H. (1993) Colloidal carriers for intravenous drug targeting: plasma protein adsorption patterns on surface-modified latex particles evaluated by two-dimensional polyacrylamide gel electrophoresis. Electrophoresis 14 (12), pp. 1382-1387.

Wenzel-Seifert, Katharina and Seifert, Roland (1993) Cyclosporin H is a potent and selective formyl peptide receptor antagonist. Comparison with N-t-butoxycarbonyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L- leucyl-L-phenylalanine and cyclosporins A, B, C, D, and E. The Journal of Immunology 150 (10), pp. 4591-4599.

Bernhardt, Günther (1993) Entwicklung und Anwendung moderner Testverfahren zur Auffindung und Optimierung der Antitumorwirkung neuartiger Diphenylethylendiaminplatin(II)-Komplexe. Habilitation, Regensburg, Universität.

Klinker, J. F. and Höer, A. and Schwaner, I. and Offermanns, S. and Wenzel-Seifert, Katharina and Seifert, Roland (1993) Lipopeptides activate Gi-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells. The Biochemical journaL 296 ( Pt 1, pp. 245-251.

Wenzel-Seifert, Katharina and Seifert, Roland (1993) Partial inhibition of human neutrophil activation by FK-506 at supratherapeutic concentrations. Naunyn-Schmiedeberg's archives of pharmacology 348 (1), pp. 7-13.

Grobecker, H. F. and Kees, Frieder K. (1993) Pharmacokinetic parameters and haemodynamic actions of midodrine in young volunteers. International angiology : a journal of the International Union of Angiology 12 (2), pp. 119-124.

Musgrave, I. F. and Genieser, H. G. and Maronde, E. and Seifert, Roland (1993) Preparations of Rp-cyclic adenosine 3',5'-phosphorothioate (Rp-cAMPS) can contain biologically active amounts of adenosine. FEBS letters 318 (3), pp. 227-230.

Rudt, S. and Blunk, Torsten and Müller, R. H. (1992) Quantification of Cell Subpopulations, Fractions of Dead
Cells and Debris in Cell Suspensions by Laser Diffractometry.
Die pharmazeutische Industrie 54 (11), pp. 966-969.

Müller, R. H. and Lherm, C. and Herbort, J. and Blunk, Torsten and Couvreur, P. (1992) Alkylcyanoacrylate drug carriers: I. Physicochemical characterization of nanoparticles with different alkyl chain length. International Journal of Pharmaceutics 84 (1), pp. 1-11.

Dominiak, P. and Kees, Frieder K. and Welzel, D. and Grobecker, H. (1992) Cardiovascular parameters and catecholamines in volunteers during passive orthostasis. Influence of antihypotensive drugs. Arzneimittel-Forschung 42 (5), pp. 637-642.

Krautwurst, D. and Seifert, Roland and Hescheler, J. and Schultz, Günter (1992) Formyl peptides and ATP stimulate Ca2+ and Na+ inward currents through non-selective cation channels via G-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells. Involvement of Ca2+ and Na+ in the activation of beta-glucuronidase release and superoxide production. The Biochemical journal 288 ( Pt 3, pp. 1025-1035.

Klinz, F. J. and Seifert, Roland and Schwaner, I. and Gausepohl, H. and Frank, R. and Schultz, Günter (1992) Generation of specific antibodies against the rap1A, rap1B and rap2 small GTP-binding proteins. Analysis of rap and ras proteins in membranes from mammalian cells. European journal of biochemistry 207 (1), pp. 207-213.

Seifert, Roland and Höer, Ariane and Offermann, Stefan and Buschauer, Armin and Schunack, Walter (1992) Histamine increases Ca^2+ in dibutyryl cyclic AMP-differentiated HL-60 cells via H_1-receptors and is an incomplete secretagogue. Mol. Pharmacol. 42, pp. 227-234.

Seifert, Roland and Höer, Ariane and Schwaner, Ingo and Buschauer, Armin (1992) Histamine increases cytosolic Ca^2+ in HL-60 promyelocytes predominantly via H_2-receptors with an unique agonist/antagonist profile and induces functional differentiation. Molecular Pharmacology 42, pp. 235-241.

Seifert, Roland and Serke, S. and Huhn, D. and Bessler, W. G. and Hauschildt, S. and Metzger, J. and Wismüller, K. H. and Jung, G. (1992) Incomplete functional differentiation of HL-60 leukemic cells by synthetic lipopeptides. Partial inhibition by pertussis toxin of enhanced superoxide formation. European journal of biochemistry / FEBS 203 (1-2), pp. 143-151.

Offermanns, S. and Seifert, Roland and Metzger, J. W. and Jung, G. and Lieberknecht, A. and Schmidt, U. and Schultz, Günter (1992) Lipopeptides are effective stimulators of tyrosine phosphorylation in human myeloid cells. Biochemical Journal 282 ( Pt 2, pp. 551-7.

Ervens, J. and Seifert, Roland (1992) Molsidomine inhibits the chemoattractant-induced respiratory burst in human neutrophils via a no-independent mechanism. Biochemical pharmacology 44 (4), pp. 637-644.

Kees, Frieder K. (1992) Orale Cephalosporine [Oral cephalosporins]. Medizinische Monatsschrift für Pharmazeuten 15 (1), pp. 2-10.

Schwaner, I. and Seifert, Roland and Schultz, Günter (1992) Receptor-mediated increases in cytosolic Ca2+ in the human erythroleukaemia cell line involve pertussis toxin-sensitive and -insensitive pathways. The Biochemical journal 281 ( Pt 2, pp. 301-307.

Kees, Frieder K. and Raasch, W. and Grobecker, H.F. (1992) Strukturelle Charakterisierung eines unbekannten Metaboliten von Ciprofloxacin [Structural characterization of an unknown metabolite of ciprofloxacin]. Arzneimittel-Forschung 42 (4), pp. 570-575.

Schwaner, I. and Seifert, Roland and Schultz, Günter (1992) The prostacyclin analogues, cicaprost and iloprost, increase cytosolic Ca2+ concentration in the human erythroleukemia cell line, HEL, via pertussis toxin-insensitive G-proteins. Eicosanoids 5 Suppl, S10-512.

Kees, Frieder K. and Lukassek, U. and Naber, K. G. and Grobecker, H. (1991) Comparative investigations on the bioavailability of cefuroxime axetil. Arzneimittel-Forschung 41 (8), pp. 843-846.

Bernhardt, Günther and Spruss, Thilo and Schönenberger, Helmut (1991) Einsatz menschlicher Tumorzellkulturen als Testmodelle bei der Entwicklung von Wirkstoffen für die Krebstherapie. Forum für interdisziplinäre Forschung : FIF 4, pp. 24-28.

Seifert, Roland and Schultz, Günter (1991) The superoxide- forming NADPH oxidase of phagocytes: an enzyme system regulated by multiple mechanisms. Reviews of physiology, biochemistry, and pharmacology, 117. Springer, Berlin. ISBN 3-540-53663-9, 0-387-53663-9.

Kees, Frieder K. and Dehner, R. and Dittrich, W. and Raasch, W. and Grobecker, H. J. (1990) Untersuchungen zur Bioverfügbarkeit von Doxycy [The bioavailability of doxycycline]. Arzneimittel-Forschung 40 (9), pp. 1039-1043.

Seifert, Roland and Schultz, Günter and Richter-Freund, M. and Metzger, J. and Wiesmüller, K. H. and Jung, G. and Bessler, W. G. and Hauschildt, S. (1990) Activation of superoxide formation and lysozyme release in human neutrophils by the synthetic lipopeptide Pam3Cys-Ser-(Lys)4. Involvement of guanine-nucleotide-binding proteins and synergism with chemotactic peptides. The Biochemical journal 267 (3), pp. 795-802.

Jungblut, P. R. and Seifert, Roland (1990) Analysis by high-resolution two-dimensional electrophoresis of differentiation-dependent alterations in cytosolic protein pattern of HL-60 leukemic cells. Journal of biochemical and biophysical methods 21 (1), pp. 47-58.

Burde, Rahel and Buschauer, Armin and Seifert, Roland (1990) Characterization of histamine H_2-receptors in human neutrophils with a series of guanidine analogues of impromidine: Are cell type-specific H_2-receptors involved in the regulation of NADPH oxidase? Naunyn-Schmiedeberg's Archives of Pharmacology 341, pp. 455-461.

Kees, Frieder K. and Raasch, W. and Steger, M. and Grobecker, H. (1990) High-performance liquid chromatographic assay for cefotiam and d3-cefotiam in human serum. Journal of Chromatography B 525 (2), pp. 484-489.

Wenzel-Seifert, Katharina and Seifert, Roland (1990) Nucleotide-, chemotactic peptide- and phorbol ester-induced exocytosis in HL-60 leukemic cells. Immunobiology 181 (4-5), pp. 298-316.

Kees, Frieder K. and Naber, K. G. (1990) Pharmakokinetik von Cefixim bei Probanden und ein Literaturvergleich mit neuen Ester Prodrug Cephalosporinen [Pharmacokinetics of cefixime in volunteers and a literature comparison with the new ester prodrug cephalosporins]. Infection 18 Suppl 3, S150-S154.

Kees, Frieder K. and Naber, K. G. and Sigl, G. and Ungethüm, W. and Grobecker, H. J. (1990) Relative bioavailability of three cefixime formulations. Arzneimittel-Forschung 40 (3), pp. 293-297.

Korting, H. C. and Schäfer-Korting, M. and Kees, Frieder K. and Lukacs, A. and Grobecker, H. (1990) Skin tissue fluid levels of cefotiam in healthy man following oral cefotiam hexetil. European journal of clinical pharmacology 39 (1), pp. 33-36.

Seifert, Roland and Burde, R. and Schultz, Günter (1989) Activation of NADPH oxidase by purine and pyrimidine nucleotides involves G proteins and is potentiated by chemotactic peptides. The Biochemical journal 259 (3), pp. 813-819.

Engel, K. J. and Schmidt, W. and Sonntag, H. G. and Kees, Frieder K. (1989) Comparative clinical and pharmacokinetic aspects of cefotetan versus cefoxitin plus metronidazole in vaginal hysterectomy. Journal of chemotherapy 1 (4 Supl), pp. 1053-1056.

Seifert, Roland and Jungblut, P. and Schultz, Günter (1989) Differential expression of cytosolic activation factors for NADPH oxidase in HL-60 leukemic cells. Biochemical and biophysical research communications 161 (3), pp. 1109-1117.

Naber, K. G. and Sörgel, F. and Kees, Frieder K. and Schumacher, H. and Sigl, G. and Zürcher, J. and Berger, S. (1989) Enoxacin-Konzentrationen in der Samenflüssigkeit, im Prostatasekret und im Prostataadenomgewebe nach oraler Gabe oder intravenöser Infusion [Enoxacin concentration in seminal fluid, in prostate secretions and in prostatic adenoma tissue following oral administration or intravenous infusion]. Infection 17 Suppl 1, S30-S66.

Schmidt, H. H. and Seifert, Roland and Böhme, E. (1989) Formation and release of nitric oxide from human neutrophils and HL-60 cells induced by a chemotactic peptide, platelet activating factor and leukotriene B4. FEBS letters 244 (2), pp. 357-360.

Rudolph, U. and Koesling, D. and Hinsch, K. D. and Seifert, Roland and Bigalke, M. and Schultz, Günter and Rosenthal, W. (1989) G-protein alpha-subunits in cytosolic and membranous fractions of human neutrophils. Molecular and cellular endocrinology 63 (1-2), pp. 143-153.

Burde, Rahel and Seifert, Roland and Buschauer, Armin and Schultz, Günther (1989) Histamine inhibits activation of human neutrophils and HL-60 leukemic cells via H_2-receptors. Naunyn-Schmiedeberg's archives of pharmacology 340, pp. 671-678.

Seifert, Roland and Schultz, Günter (1989) Involvement of pyrimidinoceptors in the regulation of cell functions by uridine and by uracil nucleotides. Trends in pharmacological sciences 10 (9), pp. 365-369.

Seifert, Roland and Burde, R. and Schultz, Günter (1989) Lack of effect of opioid peptides, morphine and naloxone on superoxide formation in human neutrophils and HL-60 leukemic cells. Naunyn-Schmiedeberg's archives of pharmacology 340 (1), pp. 101-106.

Kees, Frieder K. and Naber, K. G. and Meyer, G. P. and Grobecker, H. (1989) Pharmacokinetics of ciprofloxacin in elderly patients. Arzneimittel-Forschung 39 (4), pp. 523-527.

Naber, K. G. and Sörgel, F. and Kees, Frieder K. and Jaehde, U. and Schumacher, H. (1989) Pharmacokinetics of ciprofloxacin in young (healthy volunteers) and elderly patients, and concentrations in prostatic fluid, seminal fluid, and prostatic adenoma tissue following intravenous administration. The American journal of medicine 87 (5supl1), S57-S59.

Seifert, Roland and Wenzel, Katharina and Eckstein, F. and Schultz, Günter (1989) Purine and pyrimidine nucleotides potentiate activation of NADPH oxidase and degranulation by chemotactic peptides and induce aggregation of human neutrophils via G proteins. European journal of biochemistry / FEBS 181 (1), pp. 277-285.

Kujath, P. and Düsel, W. and Bruch, H. P. and Kees, Frieder K. (1989) The pharmacokinetic properties of cefotetan and its relevance for prophylaxis in elective colorectal surgery. Journal of chemotherapy 1 (4 Supl), pp. 1002-1004.

Seifert, Roland and Schächtele, C. and Rosenthal, W. and Schultz, Günter (1988) Activation of protein kinase C by cis- and trans-fatty acids and its potentiation by diacylglycerol. Biochemical and biophysical research communications 154 (1), pp. 20-26.

Engel, K. J. and Schmidt, W. and Sonntag, H. G. and Kees, Frieder K. (1988) Comparative clinical and pharmacokinetic aspects of cefotetan versus cefoxitin plus metronidazole in vaginal hysterectomy. Chemioterapia 7 (4), pp. 256-260.

Naber, K. G. and Sörgel, F. and Kees, Frieder K. and Schumacher, H. and Metz, R. and Grobecker, H. (1988) In-vitro activity of fleroxacin against isolates causing complicated urinary tract infections and concentrations in seminal and prostatic fluid and in prostatic adenoma tissue. The Journal of antimicrobial chemotherapy 22 Suppl D, pp. 199-207.

Kees, Frieder K. and Naber, K. G. and Schumacher, H. and Grobecker, H. (1988) Penetration of fleroxacin into prostatic secretion and prostatic adenoma tissue. Chemotherapy 34 (6), pp. 437-443.

Schächtele, C. and Seifert, Roland and Osswald, H. (1988) Stimulus-dependent inhibition of platelet aggregation by the protein kinase C inhibitors polymyxin B, H-7 and staurosporine. Biochemical and biophysical research communications 151 (1), pp. 542-547.

Seifert, Roland and Schächtele, C. (1988) Studies with protein kinase C inhibitors presently available cannot elucidate the role of protein kinase C in the activation of NADPH oxidase. Biochemical and biophysical research communications 152 (2), pp. 585-592.

Kujath, P. and Düsel, W. and Bruch, H. P. and Kees, Frieder K. (1988) The pharmacokinetic properties of cefotetan and its relevance for prophylaxis in elective colorectal surgery. Chemioterapia 7 (4), pp. 229-232.

Seifert, Roland and Rosenthal, W. and Schultz, Günter and Wieland, T. and Gierschick, P. and Jakobs, K. H. (1988) The role of nucleoside-diphosphate kinase reactions in G protein activation of NADPH oxidase by guanine and adenine nucleotides. European journal of biochemistry / FEBS 175 (1), pp. 51-55.

Seifert, Roland and Schächtele, C. and Schultz, Günter (1987) Activation of protein kinase C by cis- and trans-octadecadienoic acids in intact human platelets and its potentiation by diacylglycerol. Biochemical and biophysical research communications 149 (2), pp. 762-768.

Naber, K. and Kees, Frieder K. and Denk, K. and Bauernfeind, A. and Grobecker, H. (1987) Carumonam versus ceftazidime: in vitro activity, pharmacokinetics in elderly patients, safety and therapeutic efficacy in the treatment of complicated urinary tract infections. Chemioterapia 6 (2 Supl), pp. 517-518.

Seifert, Roland and Schultz, Günter (1987) Fatty-acid-induced activation of NADPH oxidase in plasma membranes of human neutrophils depends on neutrophil cytosol and is potentiated by stable guanine nucleotides. European journal of biochemistry / FEBS 162 (3), pp. 563-569.

Naber, K. G. and Adam, D. and Kees, Frieder K. (1987) In vitro activity and concentrations in serum, urine, prostatic secretion and adenoma tissue of ofloxacin in urological patients. Drugs 34 Suppl 1, S44-S50.

Seifert, Roland and Schultz, Günter (1987) Reversible activation of NADPH oxidase in membranes of HL-60 human leukemic cells. Biochemical and biophysical research communications 146 (3), pp. 1296-1302.

Kees, Frieder K. and Dominiak, P. and Grobecker, H. (1987) Untersuchungen zur Bioverfügbarkeit von Heptaminol bei Probanden [Bioavailability of heptaminol in healthy subjects]. Arzneimittel-Forschung 37 (10), pp. 1182-1185.

Grobecker, H. and Kees, Frieder K. and Linden, M. and Schrader, E. and Welte, S. (1987) Untersuchungen zur Bioverfügbarkeit von Midodrin und 2,5- Dimethoxyphenyl-ß-aminoethanol-hydrochlorid [The bioavailability of midodrin and alpha-2,5-dimethoxyphenyl-beta-aminoethanol hydrochloride]. Arzneimittel-Forschung 37 (4), pp. 447-450.

Dominiak, P. and Kees, Frieder K. and Grobecker, H. (1986) Circulating and tissue catecholamines in rats with chronic neurogenic hypertension. Basic research in cardiology 81 (1), pp. 20-28.

Seifert, Roland and Rosenthal, W. and Schultz, Günter (1986) Guanine nucleotides stimulate NADPH oxidase in membranes of human neutrophils. FEBS letters 205 (1), pp. 161-165.

Bernhardt, Günther (1986) Hochdruckuntersuchungen an thermophilen Bakterien. PhD, Regensburg, Universität.

Martinez, C. and Dominiak, P. and Kees, Frieder K. and Grobecker, H. (1986) Inhibition of monoamine oxidase by viloxazine in rats. Arzneimittel-Forschung 36 (5), pp. 800-803.

Seifert, Roland (1986) Nikotinamidmethylierung in normalen Geweben und Tumorzellen von Ratte und Maus. PhD, Berlin, Freie Universität.

Naber, K. G. and Dette, G. A. and Kees, Frieder K. and Knothe, H. and Grobecker, H. (1986) Pharmacokinetics, in-vitro activity, therapeutic efficacy and clinical safety of aztreonam vs. cefotaxime in the treatment of complicated urinary tract infections. The Journal of antimicrobial chemotherapy 17 (4), pp. 517-527.

Grobecker, H. and Gessler, I. and Delius, W. and Dominiak, P. and Kees, Frieder K. (1985) Effect of ketanserin on hemodynamics, plasma-catecholamine concentrations, and serotonin uptake by platelets in volunteers and patients with congestive heart failure. Journal of cardiovascular pharmacology 7, Suppl 7, S102-S104.

Kees, Frieder K. and Naber, K. G. and Bartoschik-Wich, B. and Stockmann, P. and Meyer, G. P. and Grobecker, H. (1985) High-performance liquid chromatography analysis of mezlocillin, piperacillin, their degradation products, and of ioxitalamic acid in plasma and urine of healthy volunteers. Arzneimittel-Forschung 35 (7), pp. 1099-1104.

Dominiak, P. and Kees, Frieder K. and Grobecker, H. (1985) Sympathoadrenal dysfunction in rats with chronic neurogenic hypertension. European journal of pharmacology 107 (2), pp. 263-266.

Dominiak, P. and Kees, Frieder K. and Grobecker, H. (1984) Changes in peripheral and central catecholaminergic and serotoninergic neurons of rats after acute and subacute administration of nicotine. Klinische Wochenschrift. Supplementum 62 Suppl 2, pp. 76-80.

Kees, Frieder K. and Grobecker, H. and Naber, K. G. (1984) High-performance liquid chromatographic analysis of cefotetan epimers in human plasma and urine. Journal of Chromatography B 305 (2), pp. 363-371.

Schleicher, E. D. and Kees, Frieder K. and Wieland, O. H. (1983) Analysis of total urinary catecholamines by liquid chromatography: methodology, routine experience and clinical interpretations of results. Clinica chimica acta 129 (3), pp. 295-302.

Kees, Frieder K. and Strehl, E. and Dominiak, P. and Grobecker, H. and Seeger, K. and Seidel, G. and Neuhaus, B. and Safrany, L. (1983) Cefotaxime and desacetyl cefotaxime in human bile. Infection 11 (2), pp. 118-120.

Naber, K. G. and Kees, Frieder K. and Grobecker, H. (1983) Ceftazidime: pharmacokinetics in young volunteers versus elderly patients and therapeutic efficacy with complicated urinary tract infections. The Journal of antimicrobial chemotherapy 12 Suppl A, pp. 41-45.

Kees, Frieder K. and Strehl, E. and Seeger, K. and Seidel, G. and Dominiak, P. and Grobecker, H. (1981) Comparative determination of cefotaxime and desacetyl cefotaxime in serum and bile by bioassay and high-performance liquid chromatography. Arzneimittel-Forschung 31 (2), pp. 362-365.

Kees, Frieder K. (1976) Thiaziridindioxide, Thiadiaziridindioxide und ein Beitrag zur Staudinger-Pfenninger-Reaktion. PhD, Univ. Würzburg.

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