Startseite UR

Browsen nach Dewey-Dezimal-Klassifikation

Eine Stufe nach oben
Exportieren als
[feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
Anzahl der Einträge in dieser Kategorie: 314.

Lieb, Sebastian (2016) Investigations on histamine and neuropeptide Y receptors by label-free and label-dependent methods. Dissertation, Universität Regensburg.

Lieb, Sebastian, Littmann, Timo, Plank, Nicole, Felixberger, Johannes, Tanaka, Miho, Schäfer, Thorsten, Krief, Stéphane, Elz, Sigurd, Friedland, Kristina, Bernhardt, Günther, Wegener, Joachim, Ozawa, Takeaki und Buschauer, Armin (2016) Label-free versus conventional cellular assays: functional investigations on the human histamine H1 receptor. Pharmacological Research 114, S. 13-26. Volltext nicht vorhanden.

Naporra, Franziska, Gobleder, Susanne, Wittmann, Hans-Joachim, Spindler, Julia, Bodensteiner, Michael, Bernhardt, Günther, Hübner, Harald, Gmeiner, Peter, Elz, Sigurd und Strasser, Andrea (2016) Dibenzo[b,f][1,4]oxazepines and dibenzo[b,e]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H1R, H4R, 5-HT2AR and other selected GPCRs. Pharmacological Research 113, S. 610-625. (Im Druck) Volltext nicht vorhanden.

Kunath, Julia (2016) Designermoleküle hemmen die Semaphorin 3F Wirkung in vitro, haben aber keinen Einfluss auf den Verlauf der experimentellen Arthritis. Dissertation, Universität Regensburg.

Untergehrer, Monika (2016) Analytische Untersuchungen zu phenolischen Inhaltsstoffen aus Salicis Cortex unter besonderer Berücksichtigung ihrer Metabolisierung. Dissertation, Universität Regensburg.

Hennig, Robert (2016) Multivalent nanoparticles for the treatment of ocular diseases. Dissertation, Universität Regensburg.

Wurster, Eva-Christina (2016) Layer-by-Layer assembled thin films for drug delivery: Interactions at the nano-bio interface. Dissertation, Universität Regensburg.

Kuhn, Kilian K., Ertl, Thomas, Dukorn, Stefanie, Keller, Max, Bernhardt, Günther, Reiser, Oliver und Buschauer, Armin (2016) High affinity agonists of the neuropeptide Y (NPY) Y4 receptor derived from the C-terminal pentapeptide of human pancreatic polypeptide (hPP): synthesis, stereochemical discrimination and radiolabeling. Journal of Medicinal Chemistry 59 (13), S. 6045-6058. Volltext nicht vorhanden.

Gobleder, Susanne (2016) Synthesis and pharmacological characterization of new histamine H1-/H4-receptor ligands derived from the atypical antipsychotic drug Clozapine. Dissertation, Universität Regensburg.

Kratzer, Alexander Ludwig (2016) Entwicklung und Erprobung von HPLC-basierten Methoden für das Therapeutische Drug-Monitoring von Betalaktam-Antibiotika, Linezolid und Tigecyclin – Bestimmung von freien und totalen Konzentrationen im Plasma von Intensivpatienten. Dissertation, Universität Regensburg.

Geyer, Roland, Nordemann, Uwe, Strasser, Andrea, Wittmann, Hans-Joachim und Buschauer, Armin (2016) Conformational restriction and enantioseparation increase potency and selectivity of cyanoguanidine-type histamine H4 receptor agonists. Journal of Medicinal Chemistry 59 (7), S. 3452-3470. Volltext nicht vorhanden.

Huber, Stefan (2016) Investigations on bendamustine esters as new antitumor agents and the role of ABCG2 as a surrogate marker of breast cancer initiating cells. Dissertation, Universität Regensburg.

Limmer, Franziska (2016) Funktionelle Analyse der cGMP-abhängigen Proteinkinase I in der Niere, insbesondere im dicken aufsteigenden Ast der Henle-Schleife. Dissertation, Universität Regensburg.

Edalat, Lena, Stegen, Benjamin, Klumpp, Lukas, Haehl, Erik, Schilbach, Karin, Lukowski, Robert, Kühnle, Matthias, Bernhardt, Günther, Buschauer, Armin, Zips, Daniel, Ruth, Peter und Huber, Stephan M. (2016) BK K+ channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells. Oncotarget 7 (12), S. 14259-14278. Volltext nicht vorhanden.

Felixberger, Johannes (2016) Luciferase complementation for the determination of arrestin recruitment: Investigations at histamine and NPY receptors. Dissertation, Universität Regensburg.

Stangl, Hubert Werner (2016) Arthritis and cholinergic transition of sympathetic nerve fibers. Dissertation, Universität Regensburg.

Vögeler, Jessica (2016) Pharmakotherapie und Humanpharmakologische Untersuchungen bei Patienten mit DME (Diabetisches Makulaödem) und PDR (Proliferative Diabetische Retinopathie) anhand klinischer Parameter und inflammatorischer Biomarker. Dissertation, Universität Regensburg.

Hammer, Sebastian, Gobleder, Susanne, Naporra, Franziska, Wittmann, Hans-Joachim, Elz, Sigurd, Heinrich, Markus und Strasser, Andrea (2016) 2,4-Diaminopyrimidines as dual ligands at the histamine H1 and H4 receptor - H1/H4-receptor selectivity. Bioorganic & Medicinal Chemistry Letters 26, S. 292-300. Volltext nicht vorhanden.

Dolles, Dominik, Nimczick, Martin, Scheiner, Matthias, Ramler, Jacqueline, Stadtmüller, Patricia, Sawatzky, Edgar, Drakopoulos, Antonios, Sotriffer, Christoph, Wittmann, Hans-Joachim, Strasser, Andrea und Decker, Michael (2016) Aminobenzimidazoles and structural isomers as templates for dual-acting butyrylcholinesterase inhibitors and hCB2R ligands to combat neurodegenerative disorders. ChemMedChem 11 (12), S. 1270-1283. Volltext nicht vorhanden.

Gregoritza, Manuel, Messmann, Viktoria, Goepferich, Achim und Brandl, Ferdinand (2016) Design of hydrogels for delayed antibody release utilizing hydrophobic association and Diels-Alder chemistry in tandem. Journal of Materials Chemistry B 4 (19), S. 3398-3408. Volltext nicht vorhanden.

Oswald, Mira, Geissler, Simon und Goepferich, Achim (2016) Determination of the activity of maleimide-functionalized phospholipids during preparation of liposomes. International Journal of Pharmaceutics 514, S. 93-102. Volltext nicht vorhanden.

Obreque-Balboa, José-Esteban, Sun, Qiu, Bernhardt, Günther, König, Burkhard und Buschauer, Armin (2016) Flavonoid derivatives as selective ABCC1 modulators: Synthesis and functional characterization. European Journal of Medicinal Chemistry 109, S. 124-133. Volltext nicht vorhanden.

Oswald, Mira, Platscher, Michael, Gessler, Simon und Goepferich, Achim (2016) HPLC analysis as a tool for assessing targeted liposome composition. International Journal of Pharmaceutics 497 (1-2), S. 293-300. Volltext nicht vorhanden.

Tomasetti, Luise, Liebl, Renate, Wastl, Daniel S. und Breunig, Miriam (2016) Influence of PEGylation on nanoparticle mobility in different models of the extracellular matrix. European Journal of Pharmaceutics and Biopharmaceutics 108, S. 145-155. Volltext nicht vorhanden.

Lieb, Sebastian, Michaelis, Stefanie, Plank, Nicole, Bernhardt, Günther, Buschauer, Armin und Wegener, Joachim (2016) Label-free analysis of GPCR-stimulation: The critical impact of cell adhesion. Pharmacological Research 108 (June), S. 65-74. Volltext nicht vorhanden.

Keller, Max, Kuhn, Kilian K., Einsiedel, Jürgen, Hübner, Harald, Biselli, Sabrina, Mollereau, Catherine, Wifling, David, Svobodova, Jaroslava, Bernhardt, Günther, Cabrele, Chiara, Vanderheyden, Patrick, Gmeiner, Peter und Buschauer, Armin (2016) Mimicking of arginine by functionalized Nω-carbamoylated arginine as a new broadly applicable approach to labeled bioactive peptides: high affinity angiotensin, neuropeptide Y, neuropeptide FF and neurotensin receptor ligands as examples. Journal of Medicinal Chemistry 59 (5), S. 1925-1945. Volltext nicht vorhanden.

Gregoritza, Manuel, Goepferich, Achim und Brandl, Ferdinand (2016) Polyanions effectively prevent protein conjugation and activity loss during hydrogel cross-linking. Journal of Controlled Release 238, S. 92-102. Volltext nicht vorhanden.

Kirchhof, Susanne (2015) Diels Alder Hydrogels as Intraocular Drug Delivery Systems for Antibodies. Dissertation, Universität Regensburg.

Meinel, Thomas Raphael (2015) Neuronale alpha-adrenerge Stimulation von IFN-gamma, IL-6 und CXCL1 in murinen Milzen im Tiermodell der Arthritisspätphase. Dissertation, Universität Regensburg.

Nguyen, Tri Hieu (2015) Phytochemical and biological investigation of the bark of Garcinia fusca Pierre. Dissertation, Universität Regensburg.

Helm, Klaus (2015) Synthese und funktionelle In-vitro-Pharmakologie neuer Liganden des 5-HT2A-Rezeptors aus der Klasse der Tryptamine. Dissertation, Universität Regensburg.

Werner, Kristin, Kälble, Solveig, Wolter, Sabine, Schneider, Erich H., Buschauer, Armin, Neumann, Detlef und Seifert, Roland (2015) Flow cytometric analysis with a fluorescent formyl peptide receptor ligand as a new method to study the pharmacological profile of the histamine H2-receptor. Naunyn Schmiedebergs Archives of Pharmacology 388 (10), S. 1039-1052. Volltext nicht vorhanden.

Wolferstetter, Stefanie, Reinders, Jörg, Schwede, Frank, Ruth, Peter, Schinner, Elisabeth und Schlossmann, Jens (2015) Interaction of cCMP with the cGK, cAK and MAPK Kinases in Murine Tissues. PLoS ONE 10 (5), e0126057.

Keller, Max, Schindler, Lisa, Bernhardt, Günther und Buschauer, Armin (2015) Towards labeled argininamide-type NPY Y1 receptor antagonists: Identification of a favorable propionylation site in BIBO3304. Archiv der Pharmazie 348 (6), S. 390-398. Volltext nicht vorhanden.

Rothenhöfer, Martin, Grundmann, Marco, Bernhardt, Günther, Matysik, Frank-Michael und Buschauer, Armin (2015) High performance anion exchange chromatography with pulsed amperometric detection (HPAEC–PAD) for the sensitive determination of hyaluronan oligosaccharides. Journal of Chromatography B 988 (C), S. 106-115. Volltext nicht vorhanden.

Wifling, David (2015) Constitutive activity of the human histamine H4 receptor: Molecular modelling, binding and functional studies on wild-type and mutant H4R orthologs. Dissertation, Universität Regensburg.

Mahli, Abdo (2015) Novel in vitro model for combined effects of alcohol and free fatty acids on hepatocellular lipid accumulation and inflammation. Dissertation, Universität Regensburg.

Wifling, David, Bernhardt, Günther, Dove, Stefan und Buschauer, Armin (2015) The extracellular loop 2 (ECL2) of the human histamine H4 receptor substantially contributes to ligand binding and constitutive activity. PLoS One 10 (1), S. 1-14.

Baumeister, Paul, Erdmann, Daniela, Biselli, Sabrina, Kagermeier, Nicole, Elz, Sigurd, Bernhardt, Günther und Buschauer, Armin (2015) 3HUR-DE257: Development of a tritium-labeled squaramide-type selective histamine H2 receptor antagonist. ChemMedChem 10 (1), S. 83-93. Volltext nicht vorhanden.

Orlando, Zoya, Lengers, Isabelle, Melzig, Matthias F., Buschauer, Armin, Hensel, Andreas und Jose, Joachim (2015) Autodisplay of human hyaluronidase Hyal-1 on Escherichia coli and identification of plant-derived enzyme inhibitors. Molecules 20 (9), S. 15449-15468.

Wittmann, Hans-Joachim und Strasser, Andrea (2015) Binding pathway of histamine to the hH4R, observed by unconstrained molecular dynamics. Bioorganic & Medicinal Chemistry Letters 25, S. 1259-1268. Volltext nicht vorhanden.

Kirchhof, Susanne, Gregoritza, Manuel, Messmann, Viktoria, Hammer, Nadine, Göpferich, Achim und Brandl, Ferdinand (2015) Diels-​Alder hydrogels with enhanced stability: First step toward controlled release of bevacizumab. European Journal of Pharmaceutics and Biopharmaceutics 96, S. 217-225. Volltext nicht vorhanden.

Kirchhof, Susanne, Abrami, Michela, Messmann, Viktoria, Hammer, Nadine, Goepferich, Achim, Grassi, Mario und Brandl, Ferdinand (2015) Diels–Alder hydrogels for controlled antibody release: Correlation between mesh size and release rate. Molecular Pharmaceutics 12 (9), S. 3358-3368. Volltext nicht vorhanden.

Lübker, Carolin, Dove, Stefan, Tang, Wei-Jen, Urbauer, Ramona J Bieber, Moskovitz, Jackob, Urbauer, Jeffrey L und Seifert, Roland (2015) Different Roles of N-Terminal and C-Terminal Domains in Calmodulin for Activation of Bacillus anthracis Edema Factor. Toxins 7 (7), S. 2598-2614.

Kagermeier, Nicole, Werner, Kristin, Keller, Max, Baumeister, Paul, Bernhardt, Günther, Seifert, Roland und Buschauer, Armin (2015) Dimeric carbamoylguanidine-type histamine H2 receptor ligands: A new class of potent and selective agonists. Bioorganic & Medicinal Chemistry 23 (14), S. 3957-3969. Volltext nicht vorhanden.

Huber, Stefan, Huettner, Johannes Philip, Kristina, Hacker, Bernhardt, Günther, König, Jörg und Buschauer, Armin (2015) Esters of bendamustine are by far more potent cytotoxic agents than the parent compound against human sarcoma and carcinoma cells. PLoS One 10 (7), PLoSe0133743.

Beermann, Silke, Bernhardt, Guenther, Seifert, Roland, Buschauer, Armin und Neumann, Detlef (2015) Histamine H1- and H4-receptor signaling cooperatively regulate MAPK activation. Biochemical Pharmacology 98 (3), S. 432-439. Volltext nicht vorhanden.

Strasser, Andrea und Buschauer, Armin (2015) Histaminrezeptoren. Pharmakon 3 (2), S. 109-116. Volltext nicht vorhanden.

Kirchhof, Susanne, Goepferich, Achim und Brandl, Ferdinand (2015) Hydrogels in ophthalmic applications. European Journal of Pharmaceutics and Biopharmaceutics 95, part B, S. 227-238. Volltext nicht vorhanden.

Radons, Jürgen, Falk, Werner und Dove, Stefan (2015) Identification of critical regions within the TIR domain of IL-1 receptor type I. The international journal of biochemistry & cell biology 68, S. 15-20. Volltext nicht vorhanden.

Keller, Max, Tränkle, Christian, She, Xueke, Pegoli, Andrea, Bernhardt, Günther, Buschauer, Armin und Read, Roger W. (2015) M2 subtype preferring dibenzodiazepinone-type muscarinic receptor ligands: effect of chemical homo-dimerization on orthosteric (and allosteric?) binding. Bioorganic & Medicinal Chemistry 23 (14), S. 3970-3990. Volltext nicht vorhanden.

Lübker, Carolin, Bieber-Urbauer, Ramona J., Moskovitz, Jackob, Dove, Stefan, Weisemann, Jasmin, Fedorova, Maria, Urbauer, Jeffrey L. und Seifert, Roland (2015) Membranous adenylyl cyclase 1 activation is regulated by oxidation of N- and C-terminal methionine residues in calmodulin. Biochemical Pharmacology 93 (2), S. 196-209. Volltext nicht vorhanden.

Strasser, Andrea, Wittmann, Hans-Joachim, Schneider, Erich H. und Seifert, Roland (2015) Modulation of GPCRs by monovalent cations and anions. Naunyn-Schmiedeberg's Archives of Pharmacology 388, S. 363-380. Volltext nicht vorhanden.

Wifling, David, Löffel, Karolin, Nordemann, Uwe, Strasser, Andrea, Bernhardt, Günther, Dove, Stefan, Seifert, Roland und Buschauer, Armin (2015) Molecular determinants for the high constitutive activity of the human histamine H4 receptor: Functional studies on orthologs and mutants. British Journal of Pharmacology 172, S. 785-798. Volltext nicht vorhanden.

Kaczor, Agnieszka, Guixa-Gonzalez, Ramon, Carrio, Pau, Poso, Antti, Dove, Stefan, Pastor, Manuel und Selent, Jana (2015) Multi-Component Protein - Protein Docking Based Protocol with External Scoring for Modeling Dimers of G Protein-Coupled Receptors. Molecular Informatics 34 (4), S. 246-255. Volltext nicht vorhanden.

Hennig, Robert, Ohlmann, Andreas, Staffel, Janina, Pollinger, Klaus, Haunberger, Alexandra, Breunig, Miriam, Schweda, Frank, Tamm, Ernst R. und Goepferich, Achim (2015) Multivalent nanoparticles bind the retinal and choroidal vasculature. Journal of Controlled Release 220 (Part A), S. 265-274. Volltext nicht vorhanden.

Hennig, Robert, Pollinger, Klaus, Tessmar, Joerg und Göpferich, Achim (2015) Multivalent targeting of AT1 receptors with angiotensin II-​functionalized nanoparticles. Journal of Drug Targeting, S. 1-9. Volltext nicht vorhanden.

Keller, Max, Weiss, Stefan, Hutzler, Christoph, Kuhn, Kilian K., Mollereau, Catherine, Dukorn, Stefanie, Schindler, Lisa, Bernhardt, Günther, König, Burkhard und Buschauer, Armin (2015) N(omega)-carbamoylation of the argininamide moiety: an avenue to insurmountable NPY Y1 receptor antagonists and a radiolabeled selective high affinity molecular tool ([3H]UR-MK299) with extended residence time. Journal of Medicinal Chemistry 58 (22), S. 8834-8849. Volltext nicht vorhanden.

Hennig, Robert und Goepferich, Achim (2015) Nanoparticles for the treatment of ocular neovascularizations. European Journal of Pharmaceutics and Biopharmaceutics 95 (Part B), S. 294-306. Volltext nicht vorhanden.

Sun, Qiu, Heilmann, Jörg und König, Burkhard (2015) Natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view. Beilstein Journal of Organic Chemistry 11, S. 249-264.

Kirchhof, Susanne, Strasser, Andrea, Wittmann, Hans-Joachim, Messmann, Viktoria, Hammer, Nadine, Goepferich, Achim und Brandl, Ferdinand (2015) New insights into the cross-linking and degradation mechanism of Diels–Alder hydrogels. Journal of Materials Chemistry B 3, S. 449-457.

Wurster, Eva-Christina, Liebl, Renate, Michaelis, Stefanie, Robelek, Rudolf, Wastl, Daniel S., Giessibl, Franz J., Göpferich, Achim und Breunig, Miriam (2015) Oligolayer-coated nanoparticles: impact of surface topography at the nanobio interface. ACS Applied Materials & Interfaces 7 (15), S. 7891-7900. Volltext nicht vorhanden.

Hammer, Nadine, Brandl, Ferdinand, Kirchhof, Susanne, Messmann, Viktoria und Goepferich, Achim (2015) Protein compatibility of selected cross-linking reactions for hydrogels. Macromol. Biosci. 15 (3), S. 405-413. Volltext nicht vorhanden.

Huber, Stefan, Antoni, Frauke, Schickaneder, Christian, Schickaneder, Helmut, Bernhardt, Günther und Buschauer, Armin (2015) Stabilities of neutral and basic esters of bendamustine in plasma compared to the parent compound: Kinetic investigations by HPLC. Journal of Pharmaceutical and Biomedical Analysis 104, S. 137-143. Volltext nicht vorhanden.

Reinartz, Michael T, Kälble, Solveig, Littmann, Timo, Ozawa, Takeaki, Dove, Stefan, Kaever, Volkhard, Wainer, Irving W und Seifert, Roland (2015) Structure-bias relationships for fenoterol stereoisomers in six molecular and cellular assays at the β2-adrenoceptor. Naunyn-Schmiedeberg's archives of pharmacology 388 (1), S. 51-65. Volltext nicht vorhanden.

Untergehrer, Monika, Bücherl, Daniel, Wittmann, Hans-Joachim, Strasser, Andrea, Heilmann, Jörg und Jürgenliemk, Guido (2015) Structure-dependent deconjugation of flavonoid glucuronides by human beta-glucuronidase - in vitro and in silico analyses. Planta Med. 81 (12/13), S. 1182-1189. Volltext nicht vorhanden.

Huber, Stefan, Wege, Anja K., Bernhardt, Günther, Buschauer, Armin und Brockhoff, Gero (2015) Topotecan-induced ABCG2 expression in MCF-7 cells is associated with decreased CD24 and EpCAM expression and a loss of tumorigenicity. Cytometry A 87 (8), S. 707-716. Volltext nicht vorhanden.

Herrnberger, Leonie, Hennig, Robert, Kremer, Werner, Hellerbrand, Claus, Goepferich, Achim, Kalbitzer, Hans Robert und Tamm, Ernst R. (2014) Formation of Fenestrae in Murine Liver Sinusoids Depends on Plasmalemma Vesicle-Associated Protein and Is Required for Lipoprotein Passage. PLoS ONE 9 (12), e115005.

Cuboni, Serena, Devigny, Christian, Hoogeland, Bastiaan, Strasser, Andrea, Pomplun, Sebastian, Hauger, Barbara, Höfner, Georg, Wanner, Klaus, Eder, Matthias, Buschauer, Armin, Holsboer, Florian und Hausch, Felix (2014) Loratadine and analogs: Discovery and preliminary SAR of inhibitors of the amino acid transporter B0AT2. Journal of Medicinal Chemistry 57 (22), S. 9473-9479. Volltext nicht vorhanden.

Dulla, Balakrishna (2014) Synthesis and pharmacological characterization of novel N & O containing heterocyclic compounds as potential therapeutic agents. Dissertation, Universität Regensburg.

Baumeister, Paul (2014) Molecular tools for G-protein coupled receptors:
Synthesis, pharmacological characterization and [3H]-labeling of subtype-selective ligands for histamine H4 and NPY Y2 receptors.
Dissertation, Universität Regensburg.

Hennig, Robert, Pollinger, Klaus, Veser, Anika, Breunig, Miriam und Goepferich, Achim (2014) Nanoparticle multivalency counterbalances the ligand affinity loss upon PEGylation. Journal of Controlled Release 194, S. 20-27. Volltext nicht vorhanden.

Haunschild, Gundula (2014) Nachweis und molekulare Charakterisierung EpCAM-positiver Zellen im Knochenmark von Mammakarzinom-Patientinnen. Dissertation, Universität Regensburg.

Slenczka, Alkwin, Premke, Tobias, Wirths, Eva-Maria, Pentlehner, Dominik, Lehnig, Rudolf, Richers, Ricarda und Vdovin, Alexander (2014) Microsolvation of Molecules in Superfluid Helium Nanodroplets Revealed by Means of Electronic Spectroscopy. Frontiers in Chemistry.

Schramm, Andrea (2014) Analyse renaler Funktionen der cGMP-abhängigen Proteinkinase II. Dissertation, Universität Regensburg.

Wittmann, Hans-Joachim, Seifert, Roland und Strasser, Andrea (2014) Mathematical analysis of the sodium sensitivity of the human histamine H3 receptor. In silico pharmacology 2.

Tauber, Philipp (2014) Untersuchungen zur Pathogenese von primärem Hyperaldosteronismus in neugeborenen Task3-/- Mäusen und adrenokortikalen Zellen mit KCNJ5-Mutation. Dissertation, Universität Regensburg.

Dove, Stefan (2014) Multivariate analysis of hydrophobic descriptors. ADMET & DMPK 2 (1), S. 3-17.

Dove, Stefan, Danker, Kerstin Yvonne, Stasch, Johannes-Peter, Kaever, Volkhard und Seifert, Roland (2014) Structure/Activity Relationships of (M)ANT- and TNP-Nucleotides for Inhibition of Rat Soluble Guanylyl Cyclase alpha(1)beta(1). Molecular Pharmacology 85 (4), S. 598-607. Volltext nicht vorhanden.

Rothenhöfer, Martin (2014) Analytical approaches to the study of hyaluronan and hyaluronidases: Development and application of hyphenated chromatographic and electrophoretic methods. Dissertation, Universität Regensburg.

Bücherl, Daniel (2014) Isolation of kaempferol glycosides from Ginkgo biloba leaves and synthesis, identification and quantification of their major in vivo metabolites. Dissertation, Universität Regensburg.

Kremb, Stephan, Helfer, Markus und Kraus, Birgit (2014) Aqueous Extracts of the Marine Brown Alga Lobophora variegata Inhibit HIV-1 Infection at the Level of Virus Entry into Cells. PloS ONE 9, e103895.

Pollinger, Klaus, Hennig, Robert, Bauer, Stefanie, Breunig, Miriam, Tessmar, Joerg, Buschauer, Armin, Witzgall, Ralph und Göpferich, Achim (2014) Biodistribution of quantum dots in the kidney after intravenous injection. Journal of Nanoscience and Nanotechnology 14 (5), S. 3313-3319. Volltext nicht vorhanden.

Hammer, Nadine, Brandl, Ferdinand, Kirchhof, Susanne und Goepferich, Achim (2014) Cleavable carbamate linkers for controlled protein delivery from hydrogels. Journal of Controlled Release 183, S. 67-76. Volltext nicht vorhanden.

Schweizer, Daniel, Serno, Tim und Goepferich, Achim (2014) Controlled release of therapeutic antibody formats. European Journal of Pharmaceutics and Biopharmaceutics 88 (2), S. 291-309. Volltext nicht vorhanden.

Wolter, Sabine, Dove, Stefan, Golombek, Marina, Schwede, Frank und Seifert, Roland (2014) N4-monobutyryl-cCMP activates PKA RIα and PKA RIIα more potently and with higher efficacy than PKG Iα in vitro but not in vivo. Naunyn-Schmiedeberg's archives of pharmacology 387 (12), S. 1163-1175. Volltext nicht vorhanden.

Werner, Kristin, Neumann, Detlef, Buschauer, Armin und Seifert, Roland (2014) No evidence for histamine H4-receptor in human monocytes. Journal of Pharmacology and Experimental Therapeutics 351 (3), S. 519-526. Volltext nicht vorhanden.

Wager, Eva, Wittmann, Hans-Joachim, Elz, Sigurd und Strasser, Andrea (2014) Pharmacological profile of astemizole-derived compounds at the histamine H1 and H4 receptor - H1/H4 receptor selectivity. Naunyn-Schmiedeberg's Archives of Pharmacology 387, S. 235-250. Volltext nicht vorhanden.

Luschmann, Christoph, Tessmar, Joerg , Schoeberl, Simon, Strauss, O., Luschmann, Karl und Goepferich, Achim (2014) Self-​assembling colloidal system for the ocular administration of cyclosporine A. Cornea 33 (1), S. 77-81. Volltext nicht vorhanden.

Wittmann, Hans-Joachim, Seifert, Roland und Strasser, Andrea (2014) Sodium binding to hH3R and hH4R - a molecular modelling study. Journal of Molecular Modeling 20, S. 2394. Volltext nicht vorhanden.

Geyer, Roland, Kaske, Melanie, Baumeister, Paul und Buschauer, Armin (2014) Synthesis and functional characterization of imbutamine analogs as histamine H3 and H4 receptor ligands. Archiv der Pharmazie (Weinheim, Germany) 347 (2), S. 77-88. Volltext nicht vorhanden.

Geyer, Roland, Igel, Patrick, Kaske, Melanie, Elz, Sigurd und Buschauer, Armin (2014) Synthesis, SAR and selectivity of 2-acyl- and 2-cyano-1-hetarylalkyl-guanidines at the four histamine receptor subtypes: a bioisosteric approach. MedChemComm 5 (1), S. 72-81. Volltext nicht vorhanden.

Darras, Fouad, Pockes, Steffen, Huang, Guozheng, Wehle, Sarah, Strasser, Andrea, Wittmann, Hans-Joachim, Nimczick, Martin, Sotriffer, Christoph und Decker, Michael (2014) Synthesis, biological evaluation, and computational studies of tri- and tetracyclic nitrogen-bridgehead compounds as potent dual-acting AChE inhibitors and hH3 receptor antagonists. ACS Chemical Neuroscience 5, S. 225-242. Volltext nicht vorhanden.

Endlich, Nicole, Simon, Ole, Goepferich, Achim, Wegner, Henny, Moeller, Marcus J., Rumpel, Elisabeth, Kotb, Ahmed und Endlich, Karlhans (2014) Two-Photon Microscopy Reveals Stationary Podocytes in Living Zebrafish Larvae. Journal of the American Society of Nephrology 25 (4), S. 681-686. Volltext nicht vorhanden.

Schickaneder, Helmut, Buschauer, Armin, Bernhardt, Günther, Schickaneder, Christian, Limmert, Michael, Huber, Stefan, Lubbe, Mathias und Hofmeier, Harald (2013) Esters of bendamustine and related compounds, and medical use thereof. Volltext nicht vorhanden.

Brunner, Elisabeth (2013) Einsatz von Everolimus zur Prävention der chronischen Abstoßung nach orthotoper unilateraler Lungentransplantation in der Ratte. Dissertation, Universität Regensburg.

Schmidt, Sebastian (2013) Phytochemische und pharmakologische in vitro Untersuchungen zu Hypericum empetrifolium WILLD. Dissertation, Universität Regensburg.

Loth, Tina, Hennig, Robert, Kascholke, Christian, Hötzel, Rudi und Hacker, Michael (2013) Reactive and stimuli-responsive maleic anhydride containing macromers–multi-functional cross-linkers and building blocks for hydrogel fabrication. Reactive and Functional Polymers 73 (11), S. 1480-1492. Volltext nicht vorhanden.

Sadek, Bassem, Alisch, Rudi, Buschauer, Armin und Elz, Sigurd (2013) Synthesis and dual histamine H1 and H2 receptor antagonist activity of cyanoguanidine derivatives. Molecules 18 (11), S. 14186-14202.

Dove, Stefan und Buschauer, Armin (2013) G-Protein-gekoppelte Rezeptoren: „Sinnesorgane“ der Zellen. Blick in die Wissenschaft 22 (28), S. 3-9. Volltext nicht vorhanden.

Schreeb, Annemarie, Łażewska, Dorota, Dove, Stefan, Buschauer, Armin, Kieć-Kononiwcz, Katarzyna und Stark, Holger (2013) 2. Histamine H4 receptor ligands. In: Stark, Holger, (ed.) Histamine H4 receptor: a novel drug target for immunoregulation and inflammation. Versita, London, S. 21-62. ISBN 9788376560564. Volltext nicht vorhanden.

Stöckl, Sabine (2013) Der Einfluss von Sox9 auf Zellvitalität und Differenzierungspotential von adulten mesenchymalen Stammzellen. Dissertation, Universität Regensburg.

Keller, Max, Kaske, Melanie, Holzammer, Tobias, Bernhardt, Günther und Buschauer, Armin (2013) Dimeric argininamide-type neuropeptide Y receptor antagonists: chiral discrimination between Y1 and Y4 receptors. Bioorganic and Medicinal Chemistry 21 (21), S. 6303-6322. Volltext nicht vorhanden.

Weisser, Roland (2013) Planung einer Studie zur Etablierung des therapeutischen Referenzbereichs der Wirkstoffkonzentration eines Antidementivums. Dissertation, Universität Regensburg.

Berlicki, Lukasz, Kaske, Melanie, Gutierrez-Abad, Raquel , Bernhardt, Günther , Illa, Ona , Ortuño, Rosa , Cabrele, Chiara , Buschauer, Armin und Reiser, Oliver (2013) Replacement of Thr32 and Gln34 in the C-terminal neuropeptide Y fragment 25-36 by cis-cyclobutane- and cis-cyclopentane β-amino acids shifts selectivity toward the Y4 receptor. Journal of Medicinal Chemistry 56 (21), S. 8422-8431. Volltext nicht vorhanden.

Nordemann, Uwe, Wifling, David, Schnell, David, Bernhardt, Günther, Stark, Holger, Seifert, Roland und Buschauer, Armin (2013) Luciferase reporter gene assay on human, murine and rat histamine H4 receptor orthologs: correlations and discrepancies between distal and proximal readouts. PLoS One 8 (9), e73961.

Bauer, Stefanie, Ochoa Puentes, Cristian, Sun, Qiu, Bause, Manuel, Bernhardt, Günther, König, Burkhard und Buschauer, Armin (2013) Quinoline carboxamide-type ABCG2 modulators: Indole and quinoline moieties as anilide replacements. ChemMedChem 8 (11), S. 1773-1778. Volltext nicht vorhanden.

Holzammer, Tobias (2013) Homology modeling, molecular dynamics simulations and site-directed mutagenesis of histamine H2 receptors. Dissertation, Universität Regensburg.

Kirchhof, Susanne, Brandl, Ferdinand, Hammer, Nadine und Göpferich, Achim (2013) Investigation of the Diels–Alder reaction as a cross-linking mechanism for degradable poly(ethylene glycol) based hydrogels. Journal of Materials Chemistry B 1 (37), S. 4855-4864. Volltext nicht vorhanden.

Kaske, Melanie (2013) In search for potent and selective NPY Y4 receptor ligands: acylguanidines, argininamides and peptide analogs. Dissertation, Universität Regensburg.

Brunskole Hummel, Irena, Kälble, Solveig, Burhenne, Heike, Reinartz, Michael T., Schwede, Frank, Buschauer, Armin und Seifert, Roland (2013) Dissociations in the effects of beta2-adrenergic receptor agonists on cAMP formation and superoxide production in human neutrophils: Support for the concept of functional selectivity. PLoS One 8 (5), e64556.

Zölls, Sarah, Gregoritza, Manuel, Tantipolphan, Ruedeeporn, Wiggenhorn, Michael, Winter, Gerhard, Friess, Wolfgang und Hawe, Andrea (2013) How Subvisible Particles Become Invisible - Relevance of the Refractive Index for Protein Particle Analysis. Journal of Pharmaceutical Sciences 102 (5), S. 1434-1446. Volltext nicht vorhanden.

Kees, Martin Georg, Schaeftlein, André, Haeberle, Helene Anna, Kees, Frieder K., Kloft, Charlotte und Heininger, Alexandra (2013) Population pharmacokinetics and pharmacodynamic evaluation of intravenous and enteral moxifloxacin in surgical intensive care unit patients. The Journal of antimicrobial chemotherapy. Volltext nicht vorhanden.

Ochoa-Puentes, Cristian, Bauer, Stefanie, Kühnle, Matthias, Bernhardt, Günther, Buschauer, Armin und König, Burkhard (2013) Benzanilide – Biphenyl Replacement: A Bioisosteric Approach to Quinoline Carboxamide-type ABCG2 Modulators. ACS Medicinal Chemistry Letters 4 (4), S. 393-396. Volltext nicht vorhanden.

Pluym, Nikola, Baumeister, Paul, Keller, Max, Bernhardt, Günther und Buschauer, Armin (2013) [3H]UR-PLN196: A Selective Nonpeptide Radioligand and Insurmountable Antagonist for the Neuropeptide Y Y2 Receptor. ChemMedChem 8 (4), S. 587-593. Volltext nicht vorhanden.

Miller, Tobias (2013) Polymeric micelles for solubilization and targeting of hydrophobic drugs. Dissertation, Universität Regensburg.

Seifert, Roland, Strasser, Andrea, Schneider, Erich H. , Neumann, Detlef, Dove, Stefan und Buschauer, Armin (2013) Molecular and cellular analysis of human histamine receptor subtypes. Trends in Pharmacological Sciences 34 (1), S. 33-58. Volltext nicht vorhanden.

Strasser, Andrea, Wittmann, Hans-Joachim, Buschauer, Armin, Schneider, Erich H. und Seifert, Roland (2013) Species-dependent activities of GPCR ligands: Lessons from histamine receptor orthologs. Trends in Pharmacological Sciences 34 (1), S. 13-32. Volltext nicht vorhanden.

Luschmann, Christoph, Tessmar, Joerg , Schoeberl, Simon, Framme, Carsten, Luschmann, Karl und Goepferich, Achim (2013) Developing an in situ nanosuspension: A novel approach towards the efficient administration of poorly soluble drugs at the anterior eye. European Journal of Pharmaceutical Sciences 50 (3-4), S. 385-392. Volltext nicht vorhanden.

Miller, Tobias, van Colen, G., Sander, B., Golas, M., Uezguen, Senta, Weigandt, Markus und Goepferich, Achim (2013) Drug Loading of Polymerics Micelles. Pharmaceutical Research 30 (2), S. 484-595. Volltext nicht vorhanden.

Dietrich, P., Moleda, Lukas, Kees, Frieder K., Müller, M., Straub, R. H., Hellerbrand, C. und Wiest, R. (2013) Dysbalance in sympathetic neurotransmitter release and action in cirrhotic rats: impact of exogenous neuropeptide Y. Journal of hepatology 58 (2), S. 254-261. Volltext nicht vorhanden.

Ferstl, Matthias, Drechsler, Markus, Rachel, Reinhard, Rischer, M., Engel, J., Backofen, Michael und Goepferich, Achim (2013) Impact of Polyelectrolyte Structure on the Shape of Nanoassemblies with Cationic Peptides. European Journal of Pharmaceutical Sciences 102, S. 2599-2607. Volltext nicht vorhanden.

Seifert, Roland und Dove, Stefan (2013) Inhibitors of Bacillus anthracis edema factor. Pharmacology & Therapeutics 140 (2), S. 200-212. Volltext nicht vorhanden.

Mueller, M., Blunk, Torsten, Appel, Bernhard, Maschke, Angelika, Goepferich, Achim und Zellner, J. (2013) Insulin is essential for in vitro chondrogenesis of mesenchymal progenitor cells and influences chondrogenesis in a dose-dependent manner. International orthopaedics 37 (1), S. 153-158. Volltext nicht vorhanden.

Wurster, Eva-Christina, Elbakry, Asmaa, Goepferich, Achim und Breunig, Miriam (2013) Layer-by-layer assembled gold nanoparticles for the delivery of nucleic acids. In: Nanotechnology for Nucleic Acid Delivery : Methods and Protocols. Methods in Molecular Biology, 948. Humana Press; Springer, Totowa, NJ, S. 171-182. ISBN 978-1-62703-139-4 (print), 978-1-627-03140-0 (online). Volltext nicht vorhanden.

Pollinger, Klaus, Hennig, Robert, Ohlmann, Andreas, Fuchshofer, R., Wenzel, Rebecca und Breunig, Miriam (2013) Ligand-functionalized nanoparticles target endothelial cells in retinal capillaries after systemic application. Proceedings of the National Academy of Sciences of the United States of America (PNAS) 25, S. 6115-6120. Volltext nicht vorhanden.

Strasser, Andrea und Wittmann, Hans-Joachim (2013) Modelling of GPCRs - A Practical Handbook. Springer. Volltext nicht vorhanden.

Strasser, Andrea und Wittmann, Hans-Joachim (2013) Molecular modelling studies give hint for the existence of a symmetric hb2R-Gabg-homodimer. J Mol Model 19, S. 4443-4457. Volltext nicht vorhanden.

Hozsa, Constantin, Breunig, Miriam und Goepferich, Achim (2013) Monitoring the Degradation of Reduction-Sensitive Gene Carriers with Fluorescence Spectroscopy and Flow Cytometry. Methods in Molecular Biology 991, S. 171-184. Volltext nicht vorhanden.

Luschmann, Christoph, Herrmann, W., Strauss, Olaf, Luschmann, Karl und Goepferich, Achim (2013) Ocular delivery systems for poorly soluble drugs: An in-vivo evaluation. International Journal of Pharmaceutics 455 (1-2), S. 331-337. Volltext nicht vorhanden.

Schweizer, Daniel, Voitier, I., Heier, A., Serno, Tim, Goepferich, Achim und et , al. (2013) Pharmacokinetics, biocompatibility and bioavailability of a controlled release monoclonal antibody formulation. Journal of Controlled Release 172 (3), S. 975-982. Volltext nicht vorhanden.

Miller, Tobias, Breyer, S., van Colen, G., Mier, W., Haberkorn, U., Geissler, S., Voss, S., Weigandt, Markus und Goepferich, Achim (2013) Premature drug release of polymeric micelles and its effects on tumor targeting. International Journal of Pharmaceutics 445 (1-2), S. 117-124. Volltext nicht vorhanden.

Schweizer, Daniel, Schoenhammer, K., Jahn, M. und Goepferich, Achim (2013) Protein-​Polyanion Interactions for the Controlled Release of Monoclonal Antibodies. Biomacromolecules 14 (1), S. 75-83. Volltext nicht vorhanden.

Holzhauser, C., Liebl, Renate, Goepferich, Achim , Wagenknecht, Hans-Achim und Breunig, Miriam (2013) RNA “Traffic Lights”: An Analytical Tool to Monitor siRNA Integrity. ACS chemical biology 8, S. 890-894. Volltext nicht vorhanden.

Nordemann, Uwe (2013) Radioligand binding and reporter gene assays for histamine H3 and H4 receptor species orthologs. Dissertation, Universität Regensburg.

Bodensteiner, Julian, Baumeister, Paul, Geyer, Roland, Buschauer, Armin und Reiser, Oliver (2013) Synthesis and pharmacological characterization of new tetrahydrofuran based compounds as conformationally constrained histamine receptor ligands. Organic & biomolecular chemistry 11 (24), S. 4040-4055.

Göpferich, Achim (2013) To pause a moment. European Journal of Pharmaceutics and Biopharmaceutics 85 (3), S. 328. Volltext nicht vorhanden.

Wolfertstetter, Stefanie, Huettner, Johannes Philip und Schlossmann, Jens (2013) cGMP-dependent Protein Kinase Inhibitors in Health and Disease. Pharmaceuticals 6, S. 269-286.

Ertel, Miriam, Bernhardt, Günther, Nink, Jörg und Buschauer, Armin (2012) Novel prodrugs of (1S,9S)-9-[[(1S)-1-carboxy-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid and their use in transdermal therapeutic systems. Volltext nicht vorhanden.

Memminger, Martin, Keller, Max, Lopuch, Miroslaw, Pop, Nathalie, Bernhardt, Günther, von Angerer, Erwin und Buschauer, Armin (2012) The Neuropeptide Y Y1 receptor: a diagnostic marker? Expression in MCF-7 breast cancer cells is down-regulated by antiestrogens in vitro and in xenografts. PLoS ONE 7 (12), e51032.

Löber, Stefan, Hübner, Harald, Buschauer, Armin, Sanna, Fabrizio, Argiolas, Antonio, Melis, Maria Rosaria und Gmeiner, Peter (2012) Novel azulene derivatives for the treatment of erectile dysfunction. Bioorganic & medicinal chemistry letters 22 (23), S. 7151-7154. Volltext nicht vorhanden.

Saugspier, Michael Sebastian (2012) Analysis of the anti-fibrotic effects of hop bitter acids on hepatic stellate cells and their anti-tumorigenic effects on hepatocellular carcinoma cells. Dissertation, Universität Regensburg.

Rothenhöfer, Martin, Scherübl, Rosmarie, Bernhardt, Günther, Heilmann, Jörg und Buschauer, Armin (2012) Qualitative and quantitative analysis of hyaluronan oligosaccharides with high performance thin layer chromatography using reagent-free derivatization on amino-modified silica and electrospray ionization-quadrupole time-of-flight mass spectrometry coupling on normal phase. Journal of chromatography. A 1248, S. 169-77. Volltext nicht vorhanden.

Ertel, Miriam (2012) Ambivalence of drug metabolism: Exploration of cilazapril and candesartan prodrugs for transdermal delivery and search for toxic reactive intermediates of N(G)-acylated hetarylpropylguanidines. Dissertation, Universität Regensburg.

Hild, Wolfgang (2012) Cellular nanoparticle delivery by G-protein coupled receptors. Dissertation, Universität Regensburg.

Reher, Till M., Neumann, Detlef, Buschauer, Armin und Seifert, Roland (2012) Incomplete activation of human eosinophils via the histamine H(4)-receptor: Evidence for ligand-specific receptor conformations. Biochemical Pharmacology 84 (2), S. 192-203. Volltext nicht vorhanden.

Seifert, Roland und Dove, Stefan (2012) 3/14. Molecular analysis of agonist stereoisomers at β2-adrenoceptors. In: Jozwiak , Krzysztof und Lough, W. John und Wainer, Irving W., (eds.) Drug stereochemistry : Analytical methods and pharmacology. 3. ed. Informa Healthcare, New York, S. 274-293. ISBN 9781420092387. Volltext nicht vorhanden.

Deml, Karl-Friedrich (2012) Interaktionen von Histamin H1-Rezeptoragonisten und
–antagonisten mit dem humanen Histamin H4-Rezeptor.
Dissertation, Universität Regensburg.

Birnkammer, Tobias, Spickenreither, Anja, Brunskole, Irena, Lopuch, Miroslaw, Kagermeier, Nicole, Bernhardt, Günther, Dove, Stefan, Seifert, Roland, Elz, Sigurd und Buschauer, Armin (2012) The bivalent ligand approach leads to highly potent and selective acylguanidine-type histamine H2 receptor agonists. Journal of Medicinal Chemistry 55 (3), S. 1147-1160. Volltext nicht vorhanden.

Bauhuber, Sonja, Liebl, Renate, Tomasetti, Luise, Rachel, Reinhard, Goepferich, Achim und Breunig, Miriam (2012) A library of strictly linear poly(ethylene glycol)-poly(ethylene imine) diblock coploymers to perform structure-function relationship on non-viral gene carriers. Journal of Controlled Release 162, S. 446-455. Volltext nicht vorhanden.

Miller, Tobias, Hiller, Alexandra, Uezguen, Senta, Weigandt, Markus und Goepferich, Achim (2012) Analysis of Immediate Stress Mechanisms upon Injection of Polymeric Micelles and Related Colloidal Drug Carriers. Biomacromolecules 13 (6), S. 1707-1718. Volltext nicht vorhanden.

Miller, Tobias, Rachel, Reinhard, Besheer, Ahmed, Uezguen, Senta, Weigand, Markus und Göpferich, Achim (2012) Comparative Investigations on In Vitro Serum Stability of Polymeric Micelle Formulations. Pharmaceutical Research 29 (2), S. 448-459. Volltext nicht vorhanden.

Posavec, Damir, Zabel, Manfred, Bogner, Udo, Bernhardt, Günther und Knör, Günther (2012) Functionalized derivatives of 1,4-dimethylnaphthalene as precursors for biomedical applications: synthesis, structures, spectroscopy and photochemical activation in the presence of dioxygen. Organic & biomolecular chemistry 10 (35), S. 7062-7069.

Appl, Heidrun, Holzammer, Tobias, Dove, Stefan, Haen, Ekkehard, Strasser, Andrea und Seifert, Roland (2012) Interactions of recombinant human histamine H₁R, H₂R, H₃R, and H₄R receptors with 34 antidepressants and antipsychotics. Naunyn-Schmiedeberg's archives of pharmacology 385 (2), S. 145-170. Volltext nicht vorhanden.

Pollinger, Klaus, Hennig, Robert, Breunig, Miriam, Teßmar, Jörg, Ohlmann, Andreas, Tamm, Ernst R., Witzgall, Ralph und Goepferich, Achim (2012) Kidney Podocytes as Specific Targets for cyclo(RGDfC)-Modified Nanoparticles. Small 8, S. 3368-3375. Volltext nicht vorhanden.

Elbakry, Asmaa Mohamed, Wurster, Eva-Christina, Zaky, Alaa, Liebl, Renate, Schindler, Edith, Bauer-Kreisel, Petra, Blunk, Torsten, Rachel, Reinhard, Goepferich, Achim und Breunig, Miriam (2012) Layer-by-Layer Coated Gold Nanoparticles: Size-Dependent Delivery of DNA into Cells. Small 8 (24), S. 3847-3856. Volltext nicht vorhanden.

Heller, Anne, Fischer, Lorenz H., Wolfbeis, Otto S. und Göpferich, Achim (2012) Long time monitoring of the respiratory activity of isolated mitochondria. Experimental Cell Research 318 (14), S. 1667-1672. Volltext nicht vorhanden.

Kees, Martin G., Steinke, T., Moritz, S., Rupprecht, K., Paulus, E. M., Kees, Frieder K., Bucher, M. und Faerber, L. (2012) Omeprazole impairs the absorption of mycophenolate mofetil but not of enteric-coated mycophenolate sodium in healthy volunteers. Journal of clinical pharmacology 52 (8), S. 1265-1272. Volltext nicht vorhanden.

Justinger, Christoph, Schilling, Martin K., Kees, Martin G., Kauffels, Anne, Hirschmann, Katrin, Kopp, Berit, Kees, Frieder K. und Kollmar, Otto (2012) Penetration of moxifloxacin into liver tissue. International journal of antimicrobial agents 39 (6), S. 505-509. Volltext nicht vorhanden.

Bernat, Viachaslau, Heinrich, Markus, Baumeister, Paul, Buschauer, Armin und Tschammer, Nuska (2012) Synthesis and application of the first radioligand targeting the allosteric binding pocket of chemokine receptor CXCR3. ChemMedChem 7 (8), S. 1481-1489. Volltext nicht vorhanden.

Heller, Anne, Brockhoff, Gero und Goepferich, Achim (2012) Targeting drugs to mitochondria. European Journal of Pharmaceutics and Biopharmaceutics 82, S. 1-18. Volltext nicht vorhanden.

Seifert, Roland und Dove, Stefan (2012) Towards selective inhibitors of adenylyl cyclase toxin from Bordetella pertussis. Trends in microbiology 20 (7), S. 343-351. Volltext nicht vorhanden.

Kaftan, Holger, Goepferich, Achim , Kaftan, Silke und Hosemann, Werner (2012) Two different techniques to facilitate reconstruction of the long incus process with bone cement: a feasibility study in human cadaveric temporal bones. European Archives of Oto-Rhino-Laryngology 269, S. 1431-1435. Volltext nicht vorhanden.

Strasser, Andrea und Wittmann, Hans-Joachim (2012) hb2R-Gas-complex: Prediction versus crystal structure - How valuable are predictions based on molecular modelling studies? Journal of Molecular Modeling : J Mol Model 18, S. 3439-3444. Volltext nicht vorhanden.

Brunskole, Irena (2011) Molecular and cellular analysis of aminergic G protein-coupled receptors: histamine H2, H4 and β2-adrenergic receptors, a scientific paradigm. Dissertation, Universität Regensburg.

Geyer, Roland (2011) Hetarylalkyl(aryl)cyanoguanidines as histamine H4 receptor ligands: Synthesis, chiral separation, pharmacological characterization, structure-activity and -selectivity relationships. Dissertation, Universität Regensburg.

Lopuch, Miroslaw (2011) Investigations on neuropeptide Y and histamine receptors by fluorescence-based and radiochemical methods. Dissertation, Universität Regensburg.

Erdorf, Miriam und Seifert, Roland (2011) Pharmacological characterization of adenylyl cyclase isoforms in rabbit kidney membranes. Naunyn-Schmiedeberg's Archives of Pharmacology 383 (4), S. 357-372. Volltext nicht vorhanden.

Kellermann, K., Dertinger, N., Blobner, M., Kees, Frieder, Kochs, E. F. und Jungwirt, B. (2011) Perioperative moxifloxacin treatment in rats subjected to deep hypothermic circulatory arrest: reduction in cerebral inflammation but without improvement in cognitive performance. Journal of Thoracic and Cardiovascular Surgery 141 (3), S. 796-802. Volltext nicht vorhanden.

Schinner, Elisabeth, Salb, Katharina und Schlossmann, Jens (2011) Signaling via IRAG is essential for NO/cGMP-dependent inhibition of platelet activitation. Platelets. Volltext nicht vorhanden.

Osman, Shaaban, Brandl, Ferdinand, Zayed, Gamal, Teßmar, Jörg und Göpferich, Achim (2011) Cyclodextrin based hydrogels: Inclusion complex formation and micellization of adamantane and cholesterol grafted polymers. Polymer 52 (21), S. 4806-4812. Volltext nicht vorhanden.

Schaedlich, A., Rose, C., Kuntsche, J., Caysa , H., Mueller, T., Goepferich, Achim und Maeder, K. (2011) How Stealthy are PEG-PLA Nanoparticles? An NIR In Vivo Study Combined with Detailed Size Measurements. Pharmaceutical Research 28 (8), S. 1995-2007. Volltext nicht vorhanden.

Wittmann, Hans-Joachim, Seifert, Roland und Strasser, Andrea (2011) Influence of the N-terminus and the E2-loop onto the binding kinetics of the antagonist mepyramine and the partial agonist phenoprodifen to H1R. Biochemical Pharmacology 12, S. 1910-1918. Volltext nicht vorhanden.

Wagner, Eva, Wittmann, Hans-Joachim, Elz, Sigurd und Strasser, Andrea (2011) Mepyramine-JNJ7777120-hybrid compounds show high affinity to hH1R, but low affinity to hH4R. Bioorganic & Medicinal Chemistry Letters 21, S. 6274-9280. Volltext nicht vorhanden.

Wittmann, Hans-Joachim, Elz, Sigurd, Seifert, Roland und Strasser, Andrea (2011) Na-methylated phenylhistamines exhibit affinity to the hH4R - a pharmacological and molecular modelling study. Naunyn Schmiedeberg's Arch Pharmacol 384, S. 287-299. Volltext nicht vorhanden.

Ferstl, Matthias, Strasser, Andrea, Wittmann, Hans-Joachim, Drechsler, Markus, Rischer, M., Engl, J. und Goepferich, Achim (2011) Nanofibres Resulating from Cooperative Electrostatic and Hydrophobic Interactions between Peptides and Polyelectrolytes of Opposite Charge. Langmuir 27, S. 14450-14459. Volltext nicht vorhanden.

Kees, Martin G., Weber, Susanne, Kees, Frieder K. und Horbach, Thomas (2011) Pharmacokinetics of moxifloxacin in plasma and tissue of morbidly obese patients. The Journal of antimicrobial chemotherapy 66 (10), S. 2330-2335. Volltext nicht vorhanden.

Schaedlich, A., Caysa , H., Mueller, T., Tenambergen, F, Rose, Cornelia, Goepferich, Achim , Kuntsche, J. und Maeder, K. (2011) Tumor Accumulation of NIR Fluorescent PEG PLA Nanoparticles: Impact of Particle Size and Human Xenograft Tumor Model. ACS Nano 5, S. 8710-8720. Volltext nicht vorhanden.

Kees, MG, Hilpert, JW, Gnewuch, C, Kees, F. und Voegeler, S. (2010) Clearance of vancomycin during continuous infusion in intensive care unit patients: correlation with measured and estimated creatinine clearance and serum cystatin C. International Journal of Antimicrobial Agents 36 (6), S. 545-548. Volltext nicht vorhanden.

Schnell, David, Strasser, Andrea und Seifert, Roland (2010) Comparison of the pharmacological properties of human and rat histamine H(3)-receptors. Biochemical Pharmacology 80 (9), S. 1437-1449. Volltext nicht vorhanden.

Mathar, I., Vennekens, R., Meissner, M., Kees, Frieder K., Van der Mieren , G. und Camacho Londono, J. (2010) Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice. The Journal of Clinical Investigation 120 (9), S. 3267-3279. Volltext nicht vorhanden.

Desch, Matthias, Schinner, Elisabeth, Kees, Frieder K., Hofmann, F., Seifert, Roland und Schlossmann, Jens (2010) Cyclic cytidine 3´,5´-monophosphate (cCMP) signals via cGMP kinase I. FEBS Letters 584 (18), S. 3979-3984. Volltext nicht vorhanden.

Schneider, E. H., Strasser, Andrea, Thurmond, R. L. und Seifert, Roland (2010) Structural requirements for inverse agonism and neutral antagonism of indole-, benzimidazole-, and thienopyrrole-derived histamine H4 receptor ligands. Journal of Pharmacology and Experimental Therapeutics 334 (2), S. 513-521. Volltext nicht vorhanden.

Hild, Wolfgang, Pollinger, Klaus, Caporale, Andrea, Cabrele, Chiara, Keller, Max , Pluym, Nicola , Buschauer, Armin, Rachel, Reinhard, Tessmar, Joerg , Breunig, Miriam und Goepferich, Achim (2010) G protein-coupled receptors function as logic gates for nanoparticle binding and cell uptake. Proceedings of the National Academy of Sciences USA: PNAS 107 (23), S. 10667-10672. Volltext nicht vorhanden.

Desch, Matthias, Sigl, K., Hieke, Bernhard, Salb, Katharina, Kees, F. und Bernhard, D. (2010) IRAG determines nitric oxide- and atrial natriuretic peptide-mediated smooth muscle relaxation. Cardiovascular Research 86 (3), S. 496-505. Volltext nicht vorhanden.

Schnell, David und Seifert, Roland (2010) Modulation of Histamine H(3) receptor function by monovalent ions. Neuroscience Letters 472 (2), S. 114-118. Volltext nicht vorhanden.

Schnell, David, Burleigh, Katrina, Seifert, Roland und Trick, Jonathan (2010) No evidence for functional selectivity of proxyfan at the human histamine H3 receptor coupled to defined Gi/Go protein heterotrimers. Journal of Pharmacology and Experimental Therapeutics . JPET 332 (3), S. 996-1005. Volltext nicht vorhanden.

Strasser, Andrea und Wittmann , Hans-Joachim (2010) 3D-QSAR CoMFA study to predict orientation of suprahistaprodifens and phenoprodifens in the binding-pocket of four histamine H1-receptor species. Molecular Informatics 29, S. 333-341. Volltext nicht vorhanden.

Schoenhammer, K., Boisclair, J., Schuetz, H., Petersen, H. und Göpferich, Achim (2010) Biocompatibility of an injectable in situ forming depot for peptide delivery. European Journal of Pharmaceutical Sciences 99 (10), S. 4390-4399. Volltext nicht vorhanden.

Brandl, Ferdinand, Hammer, Nadine, Blunk, Torsten, Teßmar, Jörg und Göpferich, Achim (2010) Biodegradable hydrogels for time-controlled release of tethered peptides or proteins. Biomacromolecules 11 (2), S. 496-504. Volltext nicht vorhanden.

Bauer-Kreisel, Petra, Göpferich, Achim und Blunk, Torsten (2010) Cell-delivery therapeutics for adipose tissue regeneration. Advanced Drug Delivery Reviews 62 (7-8), S. 798-813. Volltext nicht vorhanden.

Strasser, Andrea und Wittmann, Hans-Joachim (2010) Distinct interactions between the human adrenergic b2 receptor and Gas - an in silico study. J Mol Model 16, S. 1307-1318. Volltext nicht vorhanden.

Brandl, Ferdinand, Seitz, Anna Katharina, Teßmar, Jörg, Blunk, Torsten und Göpferich, Achim (2010) Enzymatically degradable poly(ethylene glycol) based hydrogels for adipose tissue engineering. Biomaterials 31 (14), S. 3957-3966. Volltext nicht vorhanden.

Brandl, Ferdinand, Kastner, Fritz, Gschwind, R. M., Blunk, Torsten, Teßmar, Jörg und Göpferich, Achim (2010) Hydrogel-based drug delivery systems: Comparison of drug diffusivity and release kinetics. Journal of Controlled Release 142 (2), S. 221-228. Volltext nicht vorhanden.

Berndl, Sina, Breunig, Miriam, Göpferich, Achim und Wagenknecht, Hans-Achim (2010) Imaging of RNA delivery to cells by thiazole orange as a fluorescent RNA base substitution. Organic & Biomolecular Chemistry 8 (5), S. 997-999. Volltext nicht vorhanden.

Schneider, Erich, Schnell, David, Strasser, Andrea, Dove, Stefan und Seifert, Roland (2010) Impact of the DRY motif and the missing "ionic lock" on constitutive activity and G-protein coupling of the human histamine H4 receptor. J Pharmacol Exp Ther : The journal of pharmacology and experimental therapeutics 333 (2), S. 382-392. Volltext nicht vorhanden.

Strasser, Andrea und Wittmann, Hans-Joachim (2010) In silico analysis of the histaprodifen induced pathway of the guinea-pig histamine H1 receptor. Journal of computer- aided molecular design : J Comput Aided Mol Des 24, S. 759-769. Volltext nicht vorhanden.

Henke, Matthias, Brandl, Ferdinand, Göpferich, Achim und Teßmar, Jörg (2010) Size-dependent release of fluorescent macromolecules and nanoparticles from radically cross-linked hydrogels. European Journal of Pharmaceutics and Biopharmaceutics 74 (2), S. 184-192. Volltext nicht vorhanden.

Holzhauser, C., Berndl, Sina, Menacher, Florian, Breunig, Miriam, Göpferich, Achim und Wagenknecht, Hans-Achim (2010) Synthesis and Optical Properties of Cyanine Dyes as Fluorescent DNA Base Substitutions for Live Cell Imaging. European Journal of Organic Chemistry (7), S. 1239-1248. Volltext nicht vorhanden.

Zaky, A., Elbakry, Asmaa, Ehmer, Axel, Breunig, Miriam und Göpferich, Achim (2010) The mechanism of protein release from triglyceride microspheres. Journal of Controlled Release 147 (2), S. 202-210. Volltext nicht vorhanden.

Göpferich, Achim und Rothschenk, Stefan (2009) Cross-linked polymer matrix, in particular for administering protein drugs into the eye. DE102008016998. Volltext nicht vorhanden.

Schoenhammer, K., Petersen, H., Guethlein, F. und Göpferich, Achim (2009) Poly(ethylene-glycol) 500 Dimethylether as Novel Solvent for Injectable In Situ Forming Depots. Pharmaceutical Research 26 (12), S. 2568-2577. Volltext nicht vorhanden.

Weiser, Barbara, Sommer, Florian, Neubauer, M., Seitz, Anna Katharina, Teßmar, Jörg, Göpferich, Achim und Blunk, Torsten (2009) Ascorbic Acid Enhances Adipogenesis of Bone Marrow-Derived Mesenchymal Stromal Cells. Cells Tissues Organs 189 (6), S. 373-381. Volltext nicht vorhanden.

Wittmann, Hans-Joachim, Seifert, Roland und Strasser, Andrea (2009) Contribution of binding enthalpy and entropy to affinity of antagonist and agonist binding at human and guinea pig histamine H1-receptor. Molecular Pharmacology 76, S. 25-37. Volltext nicht vorhanden.

Bauhuber, Sonja, Hozsa, Constantin, Breunig, Miriam und Göpferich, Achim (2009) Delivery of Nucleic Acids via Disulfide-Based Carrier Systems. Advanced Materials (Weinheim, Germany) 21 (32-33), S. 3286-3306. Volltext nicht vorhanden.

Beule, A.G., Steinmeier, E., Kaftan, H, Biebler, K.-E., Göpferich, Achim, Wolf, Eva und Hosemann, W. (2009) Effects of a dexamethasone-releasing stent on osteoneogenesis in a rabbit model. American journal of rhinology & allergy 23 (4), S. 433-436. Volltext nicht vorhanden.

Schuessele, Andrea, Mayr, H., Teßmar, Jörg und Göpferich, Achim (2009) Enhanced BMP-2 performance on hydroxyapatite ceramic surfaces. Journal of Biomedical Materials Research Part A 90A (4), S. 959-971. Volltext nicht vorhanden.

Sommer, Florian, Brandl, Ferdinand, Weiser, Barbara, Teßmar, Jörg, Blunk, Torsten und Göpferich, Achim (2009) FACS as useful tool to study distinct hyalocyte populations. Experimental Eye Research 88 (5), S. 995-999. Volltext nicht vorhanden.

Schoenhammer, K., Petersen, H., Guethlein, F. und Göpferich, Achim (2009) Injectable in situ forming depot systems: PEG-DAE as novel solvent for improved PLGA storage stability. International Journal of Pharmaceutics 371 (1-2), S. 33-39. Volltext nicht vorhanden.

Deml, Karl-Friedrich, Beermann , S, Neumann, Detlef, Strasser, Andrea und Seifert, Roland (2009) Interactions of histamine H1-receptor agonists and antagonists with the human histamine H4-receptor. Mol Pharmacol : Molecular pharmacology 76 (5), S. 1019-1030. Volltext nicht vorhanden.

Elbakry, Asmaa, Zaky, A., Liebl, Renate, Rachel, Reinhard, Göpferich, Achim und Breunig, Miriam (2009) Layer-by-Layer Assembled Gold Nanoparticles for siRNA Delivery. Nano Letters 9 (5), S. 2059-2064. Volltext nicht vorhanden.

Strasser, Andrea (2009) Molecular Modelling and QSAR-based design of histamine receptor ligands. Expert Opinion on Drug Discovery (4), S. 1061-1075. Volltext nicht vorhanden.

Appel, Bernhard, Baumer, Julia, Eyrich, Daniela, Sarhan, Hatem, Taso, S., Englert, Carsten und Göpferich, Achim (2009) Synergistic effects of growth and differentiation factor-5 (GDF-5) and insulin on expanded chondrocytes in a 3-D environment. Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 17 (11), S. 1503-1512. Volltext nicht vorhanden.

Koelwel, C., Rothschenk, Stefan, Fuchs-Koelwel, B., Gabler, B., Lohmann, C. und Göpferich, Achim (2008) Alginate inserts loaded with epidermal growth factor for the treatment of keratoconjunctivitis sicca. Pharmaceutical Development and Technology 13 (3), S. 221-231. Volltext nicht vorhanden.

Beule, A.G., Scharf, C., Biebler, K.-E., Göpferich, Achim, Steinmeier, E., Wolf, E., Hosemann, W. und Kaftan, H. (2008) Effects of Topically Applied Dexamethasone on Mucosal Wound Healing Using a Drug-Releasing Stent. The Laryngoscope 118 (11), S. 2073-2077. Volltext nicht vorhanden.

Sommer, Florian, Pollinger, Klaus, Brandl, Ferdinand, Weiser, Barbara, Teßmar, Jörg, Blunk, Torsten und Göpferich, Achim (2008) Hyalocyte proliferation and ECM accumulation modulated by bFGF and TGF-β1. Graefe's Archive for Clinical and Experimental Ophthalmology 246 (9), S. 1275-1284. Volltext nicht vorhanden.

Weiser, Barbara, Prantl, Lukas, Schubert, Thomas E. O., Zellner, J., Fischbach-Teschl, Claudia, Spruss, Thilo, Seitz, Anna Katharina, Teßmar, Jörg, Göpferich, Achim und Blunk, Torsten (2008) In Vivo Development and Long-Term Survival of Engineered Adipose Tissue Depend on In Vitro Precultivation Strategy. Tissue Engineering Part A 14 (2), S. 275-284. Volltext nicht vorhanden.

Göpferich, Achim (2008) Interactive polymers for pharmaceutical and biomedical applications. European journal of pharmaceutics and biopharmaceutics 68 (1), S. 1. Volltext nicht vorhanden.

Breunig, Miriam, Hosza, C., Lungwitz, Uta, Watanabe, K., Umeda, I., Kato, H. und Göpferich, Achim (2008) Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: Disulfide bonds boost intracellular release of the cargo. Journal of Controlled Release 130 (1), S. 57-63. Volltext nicht vorhanden.

Lungwitz, Uta, Breunig, Miriam, Liebl, Renate, Blunk, Torsten und Göpferich, Achim (2008) Methoxy poly(ethylene glycol) – Low molecular weight linear polyethylenimine-derived copolymers enable polyplex shielding. European Journal of Pharmaceutics and Biopharmaceutics 69 (1), S. 134-148. Volltext nicht vorhanden.

Preuss, Hendrik, Ghorai, Prasanta, Kraus, Anja, Dove, Stefan, Buschauer, Armin und Seifert, Roland (2007) Point Mutations in the Second Extracellular Loop of the Histamine H2 Receptor do not affect the Species-Selective Activity of Guanidine-Type Agonists. Naunyn Schmiedebergs Arch. Pharmacol. 376 (4), S. 253-264. Zugang zum Volltext eingeschränkt.

Klinker, J. F., Schwaner, I., Offermanns, S., Hagelüken, A. und Seifert, Roland (1994) Differential activation of dibutyryl cAMP-differentiated HL-60 human leukemia cells by chemoattractants. Biochemical pharmacology 48 (10), S. 1857-1864.

Wenzel-Seifert, K., Schächtele, C., Hummel, R., Grünbaum, L. und Seifert, Roland (1994) Evidence that inhibition of phorbol ester-induced superoxide anion formation by cyclosporin A in phagocytes is not mediated by direct inhibition of protein kinase C. Biochemical pharmacology 48 (5), S. 859-864.

Seifert, Roland, Grünbaum, L. und Schultz, Günter (1994) Histamine H1-receptors in HL-60 monocytes are coupled to Gi-proteins and pertussis toxin-insensitive G-proteins and mediate activation of Ca2+ influx without concomitant Ca2+ mobilization from intracellular stores. Naunyn-Schmiedeberg's archives of pharmacology 349 (4), S. 355-361.

Musgrave, I. F. und Seifert, Roland (1994) Human neutrophils and HL-60 cells do not possess alpha 2-adrenoceptors. Biochemical pharmacology 47 (2), S. 233-239.

Hagelüken, A., Grünbaum, L., Nürnberg, B., Harhammer, R., Schunack, W. und Seifert, Roland (1994) Lipophilic beta-adrenoceptor antagonists and local anesthetics are effective direct activators of G-proteins. Biochemical pharmacology 47 (10), S. 1789-1795.

Musgrave, I. F., Seifert, Roland und Schultz, Günter (1994) Maitotoxin activates cation channels distinct from the receptor-activated non-selective cation channels of HL-60 cells. The Biochemical journal 301 ( Pt 2, S. 437-441.

Klinker, J. F., Hagelüken, A., Grünbaum, L., Heilmann, I., Nürnberg, B., Harhammer, R., Offermanns, S., Schwaner, I., Ervens, J, Wenzel-Seifert, K, Müller, T. und Seifert, Roland (1994) Mastoparan may activate GTP hydrolysis by Gi-proteins in HL-60 membranes indirectly through interaction with nucleoside diphosphate kinase. The Biochemical journal 304 ( Pt 2, S. 377-383.

Wenzel-Seifert, K., Schächtele, C. und Seifert, Roland (1994) N-protein kinase C isoenzymes may be involved in the regulation of various neutrophil functions. Biochemical and biophysical research communications 200 (3), S. 1536-1543.

Blunk, Torsten (1994) Plasmaproteinadsorption auf kolloidalen Arzneistoffträgern. Analytik, Korrelation mit Oberflächeneigenschaften, Implikationen für das Drug Targeting. Dissertation, Kiel, Univ..

Naim, M., Seifert, Roland, Nürnberg, B., Grünbaum, L. und Schultz, Günter (1994) Some taste substances are direct activators of G-proteins. The Biochemical journal 297 ( Pt 3, S. 451-454.

Berger, M., Offermanns, S., Seifert, Roland und Schultz, Günter (1994) Synthetic lipopeptide Pam3CysSer(Lys)4 is an effective activator of human platelets. The American journal of physiology 266 (6 Pt 1), C1684-C1691.

Seifert, Roland, Hagelüken, A., Höer, A., Höer, D., Grünbaum, L., Offermanns, S., Schwaner, I., Zingel, V., Schunack, W. und Schultz, Günter (1994) The H1 receptor agonist 2-(3-chlorophenyl)histamine activates Gi proteins in HL-60 cells through a mechanism that is independent of known histamine receptor subtypes. Molecular Pharmacology 45 (4), S. 578-586.

Tsang, K. W., Roberts, P., Read, R. C., Kees, Frieder, Wilson, R. und Cole, P. J. (1994) The concentrations of clarithromycin and its 14-hydroxy metabolite in sputum of patients with bronchiectasis following single dose oral administration. The Journal of antimicrobial chemotherapy 33 (2), S. 289-297.

Honeybourne, D., Kees, Frieder K., Andrews, J. M., Baldwin, D. und Wise, R. (1994) The levels of clarithromycin and its 14-hydroxy metabolite in the lung. The European respiratory journal 7 (7), S. 1275-1280.

Blunk, Torsten, Mak, E. und Müller, R. H. (1993) Characterization of Colloidal Drug Carriers. Die pharmazeutische Industrie : pharmind 55 (6), S. 612-615.

Sedlmayr, T., Petersen, F., Raasch, W. und Kees, Frieder K. (1993) Clarithromycin, ein neues Makrolid-Antibiotikum. Wirksamkeit bei puerperalen Infektionen und Übertritt in die Muttermilch [Clarithromycin, a new macrolide antibiotic. Effectiveness in puerperal infections and pharmacokinetics in breast milk]. Geburtshilfe und Frauenheilkunde 53 (7), S. 488-491.

Blunk, Torsten, Hochstrasser, D. F., Sanchez, J. C., Müller, B. W. und Müller, R. H. (1993) Colloidal carriers for intravenous drug targeting: plasma protein adsorption patterns on surface-modified latex particles evaluated by two-dimensional polyacrylamide gel electrophoresis. Electrophoresis 14 (12), S. 1382-1387.

Wenzel-Seifert, Katharina und Seifert, Roland (1993) Cyclosporin H is a potent and selective formyl peptide receptor antagonist. Comparison with N-t-butoxycarbonyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L- leucyl-L-phenylalanine and cyclosporins A, B, C, D, and E. The Journal of Immunology 150 (10), S. 4591-4599.

Bernhardt, Günther (1993) Entwicklung und Anwendung moderner Testverfahren zur Auffindung und Optimierung der Antitumorwirkung neuartiger Diphenylethylendiaminplatin(II)-Komplexe. Habilitation, Regensburg, Universität.

Klinker, J. F., Höer, A., Schwaner, I., Offermanns, S., Wenzel-Seifert, Katharina und Seifert, Roland (1993) Lipopeptides activate Gi-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells. The Biochemical journaL 296 ( Pt 1, S. 245-251.

Wenzel-Seifert, Katharina und Seifert, Roland (1993) Partial inhibition of human neutrophil activation by FK-506 at supratherapeutic concentrations. Naunyn-Schmiedeberg's archives of pharmacology 348 (1), S. 7-13.

Grobecker, H. F. und Kees, Frieder K. (1993) Pharmacokinetic parameters and haemodynamic actions of midodrine in young volunteers. International angiology : a journal of the International Union of Angiology 12 (2), S. 119-124.

Musgrave, I. F., Genieser, H. G., Maronde, E. und Seifert, Roland (1993) Preparations of Rp-cyclic adenosine 3',5'-phosphorothioate (Rp-cAMPS) can contain biologically active amounts of adenosine. FEBS letters 318 (3), S. 227-230.

Rudt, S., Blunk, Torsten und Müller, R. H. (1992) Quantification of Cell Subpopulations, Fractions of Dead
Cells and Debris in Cell Suspensions by Laser Diffractometry.
Die pharmazeutische Industrie 54 (11), S. 966-969.

Müller, R. H., Lherm, C., Herbort, J., Blunk, Torsten und Couvreur, P. (1992) Alkylcyanoacrylate drug carriers: I. Physicochemical characterization of nanoparticles with different alkyl chain length. International Journal of Pharmaceutics 84 (1), S. 1-11.

Dominiak, P., Kees, Frieder K., Welzel, D. und Grobecker, H. (1992) Cardiovascular parameters and catecholamines in volunteers during passive orthostasis. Influence of antihypotensive drugs. Arzneimittel-Forschung 42 (5), S. 637-642.

Krautwurst, D., Seifert, Roland, Hescheler, J. und Schultz, Günter (1992) Formyl peptides and ATP stimulate Ca2+ and Na+ inward currents through non-selective cation channels via G-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells. Involvement of Ca2+ and Na+ in the activation of beta-glucuronidase release and superoxide production. The Biochemical journal 288 ( Pt 3, S. 1025-1035.

Klinz, F. J., Seifert, Roland, Schwaner, I., Gausepohl, H., Frank, R. und Schultz, Günter (1992) Generation of specific antibodies against the rap1A, rap1B and rap2 small GTP-binding proteins. Analysis of rap and ras proteins in membranes from mammalian cells. European journal of biochemistry 207 (1), S. 207-213.

Seifert, Roland, Höer, Ariane, Offermann, Stefan, Buschauer, Armin und Schunack, Walter (1992) Histamine increases Ca^2+ in dibutyryl cyclic AMP-differentiated HL-60 cells via H_1-receptors and is an incomplete secretagogue. Mol. Pharmacol. 42, S. 227-234.

Seifert, Roland, Höer, Ariane, Schwaner, Ingo und Buschauer, Armin (1992) Histamine increases cytosolic Ca^2+ in HL-60 promyelocytes predominantly via H_2-receptors with an unique agonist/antagonist profile and induces functional differentiation. Molecular Pharmacology 42, S. 235-241.

Seifert, Roland, Serke, S., Huhn, D., Bessler, W. G., Hauschildt, S., Metzger, J., Wismüller, K. H. und Jung, G. (1992) Incomplete functional differentiation of HL-60 leukemic cells by synthetic lipopeptides. Partial inhibition by pertussis toxin of enhanced superoxide formation. European journal of biochemistry / FEBS 203 (1-2), S. 143-151.

Offermanns, S., Seifert, Roland, Metzger, J. W., Jung, G., Lieberknecht, A., Schmidt, U. und Schultz, Günter (1992) Lipopeptides are effective stimulators of tyrosine phosphorylation in human myeloid cells. Biochemical Journal 282 ( Pt 2, S. 551-7.

Ervens, J. und Seifert, Roland (1992) Molsidomine inhibits the chemoattractant-induced respiratory burst in human neutrophils via a no-independent mechanism. Biochemical pharmacology 44 (4), S. 637-644.

Kees, Frieder K. (1992) Orale Cephalosporine [Oral cephalosporins]. Medizinische Monatsschrift für Pharmazeuten 15 (1), S. 2-10.

Schwaner, I., Seifert, Roland und Schultz, Günter (1992) Receptor-mediated increases in cytosolic Ca2+ in the human erythroleukaemia cell line involve pertussis toxin-sensitive and -insensitive pathways. The Biochemical journal 281 ( Pt 2, S. 301-307.

Kees, Frieder K., Raasch, W. und Grobecker, H.F. (1992) Strukturelle Charakterisierung eines unbekannten Metaboliten von Ciprofloxacin [Structural characterization of an unknown metabolite of ciprofloxacin]. Arzneimittel-Forschung 42 (4), S. 570-575.

Schwaner, I., Seifert, Roland und Schultz, Günter (1992) The prostacyclin analogues, cicaprost and iloprost, increase cytosolic Ca2+ concentration in the human erythroleukemia cell line, HEL, via pertussis toxin-insensitive G-proteins. Eicosanoids 5 Suppl, S10-512. Volltext nicht vorhanden.

Kees, Frieder K., Lukassek, U., Naber, K. G. und Grobecker, H. (1991) Comparative investigations on the bioavailability of cefuroxime axetil. Arzneimittel-Forschung 41 (8), S. 843-846.

Bernhardt, Günther, Spruss, Thilo und Schönenberger, Helmut (1991) Einsatz menschlicher Tumorzellkulturen als Testmodelle bei der Entwicklung von Wirkstoffen für die Krebstherapie. Forum für interdisziplinäre Forschung : FIF 4, S. 24-28.

Seifert, Roland und Schultz, Günter (1991) The superoxide- forming NADPH oxidase of phagocytes: an enzyme system regulated by multiple mechanisms. Reviews of physiology, biochemistry, and pharmacology, 117. Springer, Berlin. ISBN 3-540-53663-9, 0-387-53663-9.

Kees, Frieder K., Dehner, R., Dittrich, W., Raasch, W. und Grobecker, H. J. (1990) Untersuchungen zur Bioverfügbarkeit von Doxycy [The bioavailability of doxycycline]. Arzneimittel-Forschung 40 (9), S. 1039-1043.

Seifert, Roland, Schultz, Günter, Richter-Freund, M., Metzger, J., Wiesmüller, K. H., Jung, G., Bessler, W. G. und Hauschildt, S. (1990) Activation of superoxide formation and lysozyme release in human neutrophils by the synthetic lipopeptide Pam3Cys-Ser-(Lys)4. Involvement of guanine-nucleotide-binding proteins and synergism with chemotactic peptides. The Biochemical journal 267 (3), S. 795-802.

Jungblut, P. R. und Seifert, Roland (1990) Analysis by high-resolution two-dimensional electrophoresis of differentiation-dependent alterations in cytosolic protein pattern of HL-60 leukemic cells. Journal of biochemical and biophysical methods 21 (1), S. 47-58.

Burde, Rahel, Buschauer, Armin und Seifert, Roland (1990) Characterization of histamine H_2-receptors in human neutrophils with a series of guanidine analogues of impromidine: Are cell type-specific H_2-receptors involved in the regulation of NADPH oxidase? Naunyn-Schmiedeberg's Archives of Pharmacology 341, S. 455-461.

Kees, Frieder K., Raasch, W., Steger, M. und Grobecker, H. (1990) High-performance liquid chromatographic assay for cefotiam and d3-cefotiam in human serum. Journal of Chromatography B 525 (2), S. 484-489.

Wenzel-Seifert, Katharina und Seifert, Roland (1990) Nucleotide-, chemotactic peptide- and phorbol ester-induced exocytosis in HL-60 leukemic cells. Immunobiology 181 (4-5), S. 298-316.

Kees, Frieder K. und Naber, K. G. (1990) Pharmakokinetik von Cefixim bei Probanden und ein Literaturvergleich mit neuen Ester Prodrug Cephalosporinen [Pharmacokinetics of cefixime in volunteers and a literature comparison with the new ester prodrug cephalosporins]. Infection 18 Suppl 3, S150-S154.

Kees, Frieder K., Naber, K. G., Sigl, G., Ungethüm, W. und Grobecker, H. J. (1990) Relative bioavailability of three cefixime formulations. Arzneimittel-Forschung 40 (3), S. 293-297.

Korting, H. C., Schäfer-Korting, M., Kees, Frieder K., Lukacs, A. und Grobecker, H. (1990) Skin tissue fluid levels of cefotiam in healthy man following oral cefotiam hexetil. European journal of clinical pharmacology 39 (1), S. 33-36.

Seifert, Roland, Burde, R. und Schultz, Günter (1989) Activation of NADPH oxidase by purine and pyrimidine nucleotides involves G proteins and is potentiated by chemotactic peptides. The Biochemical journal 259 (3), S. 813-819.

Engel, K. J., Schmidt, W., Sonntag, H. G. und Kees, Frieder K. (1989) Comparative clinical and pharmacokinetic aspects of cefotetan versus cefoxitin plus metronidazole in vaginal hysterectomy. Journal of chemotherapy 1 (4 Supl), S. 1053-1056. Volltext nicht vorhanden.

Seifert, Roland, Jungblut, P. und Schultz, Günter (1989) Differential expression of cytosolic activation factors for NADPH oxidase in HL-60 leukemic cells. Biochemical and biophysical research communications 161 (3), S. 1109-1117.

Naber, K. G., Sörgel, F., Kees, Frieder K., Schumacher, H., Sigl, G., Zürcher, J. und Berger, S. (1989) Enoxacin-Konzentrationen in der Samenflüssigkeit, im Prostatasekret und im Prostataadenomgewebe nach oraler Gabe oder intravenöser Infusion [Enoxacin concentration in seminal fluid, in prostate secretions and in prostatic adenoma tissue following oral administration or intravenous infusion]. Infection 17 Suppl 1, S30-S66.

Schmidt, H. H., Seifert, Roland und Böhme, E. (1989) Formation and release of nitric oxide from human neutrophils and HL-60 cells induced by a chemotactic peptide, platelet activating factor and leukotriene B4. FEBS letters 244 (2), S. 357-360.

Rudolph, U., Koesling, D., Hinsch, K. D., Seifert, Roland, Bigalke, M., Schultz, Günter und Rosenthal, W. (1989) G-protein alpha-subunits in cytosolic and membranous fractions of human neutrophils. Molecular and cellular endocrinology 63 (1-2), S. 143-153.

Burde, Rahel, Seifert, Roland, Buschauer, Armin und Schultz, Günther (1989) Histamine inhibits activation of human neutrophils and HL-60 leukemic cells via H_2-receptors. Naunyn-Schmiedeberg's archives of pharmacology 340, S. 671-678.

Seifert, Roland und Schultz, Günter (1989) Involvement of pyrimidinoceptors in the regulation of cell functions by uridine and by uracil nucleotides. Trends in pharmacological sciences 10 (9), S. 365-369.

Seifert, Roland, Burde, R. und Schultz, Günter (1989) Lack of effect of opioid peptides, morphine and naloxone on superoxide formation in human neutrophils and HL-60 leukemic cells. Naunyn-Schmiedeberg's archives of pharmacology 340 (1), S. 101-106.

Kees, Frieder K., Naber, K. G., Meyer, G. P. und Grobecker, H. (1989) Pharmacokinetics of ciprofloxacin in elderly patients. Arzneimittel-Forschung 39 (4), S. 523-527.

Naber, K. G., Sörgel, F., Kees, Frieder K., Jaehde, U. und Schumacher, H. (1989) Pharmacokinetics of ciprofloxacin in young (healthy volunteers) and elderly patients, and concentrations in prostatic fluid, seminal fluid, and prostatic adenoma tissue following intravenous administration. The American journal of medicine 87 (5supl1), S57-S59.

Seifert, Roland, Wenzel, Katharina, Eckstein, F. und Schultz, Günter (1989) Purine and pyrimidine nucleotides potentiate activation of NADPH oxidase and degranulation by chemotactic peptides and induce aggregation of human neutrophils via G proteins. European journal of biochemistry / FEBS 181 (1), S. 277-285.

Kujath, P., Düsel, W., Bruch, H. P. und Kees, Frieder K. (1989) The pharmacokinetic properties of cefotetan and its relevance for prophylaxis in elective colorectal surgery. Journal of chemotherapy 1 (4 Supl), S. 1002-1004. Volltext nicht vorhanden.

Seifert, Roland, Schächtele, C., Rosenthal, W. und Schultz, Günter (1988) Activation of protein kinase C by cis- and trans-fatty acids and its potentiation by diacylglycerol. Biochemical and biophysical research communications 154 (1), S. 20-26.

Engel, K. J., Schmidt, W., Sonntag, H. G. und Kees, Frieder K. (1988) Comparative clinical and pharmacokinetic aspects of cefotetan versus cefoxitin plus metronidazole in vaginal hysterectomy. Chemioterapia 7 (4), S. 256-260. Volltext nicht vorhanden.

Naber, K. G., Sörgel, F., Kees, Frieder K., Schumacher, H., Metz, R. und Grobecker, H. (1988) In-vitro activity of fleroxacin against isolates causing complicated urinary tract infections and concentrations in seminal and prostatic fluid and in prostatic adenoma tissue. The Journal of antimicrobial chemotherapy 22 Suppl D, S. 199-207.

Kees, Frieder K., Naber, K. G., Schumacher, H. und Grobecker, H. (1988) Penetration of fleroxacin into prostatic secretion and prostatic adenoma tissue. Chemotherapy 34 (6), S. 437-443. Volltext nicht vorhanden.

Schächtele, C., Seifert, Roland und Osswald, H. (1988) Stimulus-dependent inhibition of platelet aggregation by the protein kinase C inhibitors polymyxin B, H-7 and staurosporine. Biochemical and biophysical research communications 151 (1), S. 542-547.

Seifert, Roland und Schächtele, C. (1988) Studies with protein kinase C inhibitors presently available cannot elucidate the role of protein kinase C in the activation of NADPH oxidase. Biochemical and biophysical research communications 152 (2), S. 585-592.

Kujath, P., Düsel, W., Bruch, H. P. und Kees, Frieder K. (1988) The pharmacokinetic properties of cefotetan and its relevance for prophylaxis in elective colorectal surgery. Chemioterapia 7 (4), S. 229-232. Volltext nicht vorhanden.

Seifert, Roland, Rosenthal, W., Schultz, Günter, Wieland, T., Gierschick, P. und Jakobs, K. H. (1988) The role of nucleoside-diphosphate kinase reactions in G protein activation of NADPH oxidase by guanine and adenine nucleotides. European journal of biochemistry / FEBS 175 (1), S. 51-55.

Seifert, Roland, Schächtele, C. und Schultz, Günter (1987) Activation of protein kinase C by cis- and trans-octadecadienoic acids in intact human platelets and its potentiation by diacylglycerol. Biochemical and biophysical research communications 149 (2), S. 762-768.

Naber, K., Kees, Frieder K., Denk, K., Bauernfeind, A. und Grobecker, H. (1987) Carumonam versus ceftazidime: in vitro activity, pharmacokinetics in elderly patients, safety and therapeutic efficacy in the treatment of complicated urinary tract infections. Chemioterapia 6 (2 Supl), S. 517-518. Volltext nicht vorhanden.

Seifert, Roland und Schultz, Günter (1987) Fatty-acid-induced activation of NADPH oxidase in plasma membranes of human neutrophils depends on neutrophil cytosol and is potentiated by stable guanine nucleotides. European journal of biochemistry / FEBS 162 (3), S. 563-569.

Naber, K. G., Adam, D. und Kees, Frieder K. (1987) In vitro activity and concentrations in serum, urine, prostatic secretion and adenoma tissue of ofloxacin in urological patients. Drugs 34 Suppl 1, S44-S50. Volltext nicht vorhanden.

Seifert, Roland und Schultz, Günter (1987) Reversible activation of NADPH oxidase in membranes of HL-60 human leukemic cells. Biochemical and biophysical research communications 146 (3), S. 1296-1302.

Kees, Frieder K., Dominiak, P. und Grobecker, H. (1987) Untersuchungen zur Bioverfügbarkeit von Heptaminol bei Probanden [Bioavailability of heptaminol in healthy subjects]. Arzneimittel-Forschung 37 (10), S. 1182-1185.

Grobecker, H., Kees, Frieder K., Linden, M., Schrader, E. und Welte, S. (1987) Untersuchungen zur Bioverfügbarkeit von Midodrin und 2,5- Dimethoxyphenyl-ß-aminoethanol-hydrochlorid [The bioavailability of midodrin and alpha-2,5-dimethoxyphenyl-beta-aminoethanol hydrochloride]. Arzneimittel-Forschung 37 (4), S. 447-450.

Dominiak, P., Kees, Frieder K. und Grobecker, H. (1986) Circulating and tissue catecholamines in rats with chronic neurogenic hypertension. Basic research in cardiology 81 (1), S. 20-28.

Seifert, Roland, Rosenthal, W. und Schultz, Günter (1986) Guanine nucleotides stimulate NADPH oxidase in membranes of human neutrophils. FEBS letters 205 (1), S. 161-165.

Bernhardt, Günther (1986) Hochdruckuntersuchungen an thermophilen Bakterien. Dissertation, Regensburg, Universität.

Martinez, C., Dominiak, P., Kees, Frieder K. und Grobecker, H. (1986) Inhibition of monoamine oxidase by viloxazine in rats. Arzneimittel-Forschung 36 (5), S. 800-803.

Seifert, Roland (1986) Nikotinamidmethylierung in normalen Geweben und Tumorzellen von Ratte und Maus. Dissertation, Berlin, Freie Universität.

Naber, K. G., Dette, G. A., Kees, Frieder K., Knothe, H. und Grobecker, H. (1986) Pharmacokinetics, in-vitro activity, therapeutic efficacy and clinical safety of aztreonam vs. cefotaxime in the treatment of complicated urinary tract infections. The Journal of antimicrobial chemotherapy 17 (4), S. 517-527.

Grobecker, H., Gessler, I., Delius, W., Dominiak, P. und Kees, Frieder K. (1985) Effect of ketanserin on hemodynamics, plasma-catecholamine concentrations, and serotonin uptake by platelets in volunteers and patients with congestive heart failure. Journal of cardiovascular pharmacology 7, Suppl 7, S102-S104.

Kees, Frieder K., Naber, K. G., Bartoschik-Wich, B., Stockmann, P., Meyer, G. P. und Grobecker, H. (1985) High-performance liquid chromatography analysis of mezlocillin, piperacillin, their degradation products, and of ioxitalamic acid in plasma and urine of healthy volunteers. Arzneimittel-Forschung 35 (7), S. 1099-1104.

Dominiak, P., Kees, Frieder K. und Grobecker, H. (1985) Sympathoadrenal dysfunction in rats with chronic neurogenic hypertension. European journal of pharmacology 107 (2), S. 263-266.

Dominiak, P., Kees, Frieder K. und Grobecker, H. (1984) Changes in peripheral and central catecholaminergic and serotoninergic neurons of rats after acute and subacute administration of nicotine. Klinische Wochenschrift. Supplementum 62 Suppl 2, S. 76-80. Volltext nicht vorhanden.

Kees, Frieder K., Grobecker, H. und Naber, K. G. (1984) High-performance liquid chromatographic analysis of cefotetan epimers in human plasma and urine. Journal of Chromatography B 305 (2), S. 363-371.

Schleicher, E. D., Kees, Frieder K. und Wieland, O. H. (1983) Analysis of total urinary catecholamines by liquid chromatography: methodology, routine experience and clinical interpretations of results. Clinica chimica acta 129 (3), S. 295-302.

Kees, Frieder K., Strehl, E., Dominiak, P., Grobecker, H., Seeger, K., Seidel, G., Neuhaus, B. und Safrany, L. (1983) Cefotaxime and desacetyl cefotaxime in human bile. Infection 11 (2), S. 118-120.

Naber, K. G., Kees, Frieder K. und Grobecker, H. (1983) Ceftazidime: pharmacokinetics in young volunteers versus elderly patients and therapeutic efficacy with complicated urinary tract infections. The Journal of antimicrobial chemotherapy 12 Suppl A, S. 41-45.

Kees, Frieder K., Strehl, E., Seeger, K., Seidel, G., Dominiak, P. und Grobecker, H. (1981) Comparative determination of cefotaxime and desacetyl cefotaxime in serum and bile by bioassay and high-performance liquid chromatography. Arzneimittel-Forschung 31 (2), S. 362-365.

Kees, Frieder K. (1976) Thiaziridindioxide, Thiadiaziridindioxide und ein Beitrag zur Staudinger-Pfenninger-Reaktion. Dissertation, Univ. Würzburg. Volltext nicht vorhanden.

Diese Liste wurde erzeugt am Sun Dec 4 21:23:35 2016 CET.
  1. Universität

Universitätsbibliothek

Publikationsserver

Kontakt:

Publizieren: oa@ur.de

Dissertationen: dissertationen@ur.de

Forschungsdaten: daten@ur.de

Ansprechpartner